Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | IA-alkyne | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 100 uM | |||||
| Criteria | Quantification: Probe vs (Probe+Competitor) | |||||
| Quantitative Method |
Isotope tag
|
|||||
| Competitor Name | Fragment14 | Competitor Info | ||||
| Competitor Concentration | 200 uM | |||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Lymph node | ||||
| Disease Model | Burkitt lymphoma [ICD-11:2A85] | |||||
| Model Name | Human burkitt lymphoma cells (Ramos) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP00701 | D-3-phosphoglycerate dehydrogenase (PHGDH) | C369 | 20.0 | |||
| LDTP00414 | Dual specificity mitogen-activated protein kinase kinase 7 (MAP2K7) | C131 | 20.0 | |||
| LDTP01055 | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (PFKFB2) | C158 | 14.2 | |||
| LDTP12405 | Fructose-2,6-bisphosphatase TIGAR (TIGAR) | C114 | 5.1 | |||
| LDTP05075 | Tubulin alpha-4A chain (TUBA4A) | C54 | 5.1 | |||
| LDTP03401 | Multifunctional protein CAD (CAD) | C73 | 3.7 | |||
| LDTP00601 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (OGT) | C758 | 2.9 | |||
| LDTP00479 | Histone acetyltransferase type B catalytic subunit (HAT1) | C101 | 1.9 | |||
| LDTP05943 | Myotubularin-related protein 1 (MTMR1) | C117 | 1.7 | |||
| LDTP12539 | DNA dC->dU-editing enzyme APOBEC-3C (APOBEC3C) | C130 | 1.4 | |||
| LDTP18330 | Haloacid dehalogenase-like hydrolase domain-containing 5 (HDHD5) | C392 | 1.1 | |||
| LDTP05912 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) | C113 | 1.0 | |||
| LDTP03291 | Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) | C413 | 0.8 | |||
| LDTP03998 | 3-ketoacyl-CoA thiolase, mitochondrial (ACAA2) | C92 | 0.8 | |||
| LDTP02677 | Protein disulfide-isomerase A4 (PDIA4) | C206 | 0.7 | |||
| LDTP02038 | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) | C152 | 0.6 | |||
Transporter and channel
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP08769 | Nuclear pore complex protein Nup93 (NUP93) | C522 | 20.0 | |||
Other
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP10843 | MMS19 nucleotide excision repair protein homolog (MMS19) | C848 | 20.0 | |||
| LDTP06250 | Proteasome activator complex subunit 4 (PSME4) | C1840 | 20.0 | |||
| LDTP01532 | ZW10 interactor (ZWINT) | C54 | 20.0 | |||
| LDTP15861 | Acyl-CoA-binding domain-containing protein 6 (ACBD6) | C267 | 6.9 | |||
| LDTP14250 | Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1) | C51 | 4.3 | |||
| LDTP12571 | LanC-like protein 2 (LANCL2) | C187 | 3.3 | |||
| LDTP10781 | NudC domain-containing protein 1 (NUDCD1) | C376 | 1.8 | |||
| LDTP12669 | Mediator of RNA polymerase II transcription subunit 17 (MED17) | C649 | 1.4 | |||
| LDTP04952 | Heterogeneous nuclear ribonucleoprotein K (HNRNPK) | C132 | 0.9 | |||
| LDTP12651 | TBC1 domain family member 23 (TBC1D23) | C283 | 0.6 | |||