Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | Dasatinib-CA-3PAP | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 1 uM | |||||
| Criteria | Quantification: Probe vs (Probe+Competitor) | |||||
| Quantitative Method |
LFQ
|
|||||
| Competitor Name | Dasatinib | Competitor Info | ||||
| Competitor Concentration | 20 uM | |||||
| In Vivo Experiment Model | Model Type |
|
Cell lysate | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Chronic myeloid leukemia [ICD-11:2A20] | |||||
| Model Name | Human chronic myeloid leukemia cell lysate (K562) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03198 | Ferrochelatase, mitochondrial (FECH) | 4.9 | ||||
| LDTP03703 | Trypsin-3 (PRSS3) | 4.5 | ||||
| LDTP04689 | Adenosine kinase (ADK) | 4.4 | ||||
| LDTP12681 | ATPase family AAA domain-containing protein 3A (ATAD3A) | 4.3 | ||||
| LDTP02560 | Breakpoint cluster region protein (BCR) | . | ||||
| LDTP04631 | Ephrin type-B receptor 4 (EPHB4) | . | ||||
| LDTP10930 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) | . | ||||
| LDTP06547 | Mitogen-activated protein kinase 14 (MAPK14) | . | ||||
| LDTP02638 | Proto-oncogene tyrosine-protein kinase Src (SRC) | . | ||||
| LDTP00751 | Receptor-interacting serine/threonine-protein kinase 2 (RIPK2) | . | ||||
| LDTP01784 | Tyrosine-protein kinase ABL1 (ABL1) | . | ||||
| LDTP03991 | Tyrosine-protein kinase ABL2 (ABL2) | . | ||||
| LDTP05478 | Tyrosine-protein kinase BTK (BTK) | . | ||||
| LDTP02139 | Tyrosine-protein kinase Fyn (FYN) | . | ||||
| LDTP02232 | Tyrosine-protein kinase Lyn (LYN) | . | ||||
| LDTP02231 | Tyrosine-protein kinase Yes (YES1) | . | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP04107 | Large ribosomal subunit protein eL21 (RPL21) | 6.5 | ||||
| LDTP05378 | Large ribosomal subunit protein eL6 (RPL6) | 5.0 | ||||
| LDTP06055 | Eukaryotic translation initiation factor 3 subunit A (EIF3A) | 4.5 | ||||
| LDTP02292 | U1 small nuclear ribonucleoprotein 70 kDa (SNRNP70) | 4.0 | ||||
