Details of the Target

General Information of Target

Target ID LDTP18592
Target Name Soluble lamin-associated protein of 75 kDa (FAM169A)
Gene Name FAM169A
Gene ID 26049
Synonyms
KIAA0888; Soluble lamin-associated protein of 75 kDa; SLAP75; Protein FAM169A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGPAARPALRSPPPPPPPPPSPLLLLLPLLPLWLGLAGPGAAADGSEPAAGAGRGGARAV
RVDVRLPRQDALVLEGVRIGSEADPAPLLGGRLLLMDIVDAEQEAPVEGWIAVAYVGKEQ
AAQFHQENKGSGPQAYPKALVQQMRRALFLGASALLLLILNHNVVRELDISQLLLRPVIV
LHYSSNVTKLLDALLQRTQATAEITSGESLSANIEWKLTLWTTCGLSKDGYGGWQDLVCL
GGSRAQEQKPLQQLWNAILLVAMLLCTGLVVQAQRQASRQSQRELGGQVDLFKRRVVRRL
ASLKTRRCRLSRAAQGLPDPGAETCAVCLDYFCNKQWLRVLPCKHEFHRDCVDPWLMLQQ
TCPLCKFNVLGNRYSDD
Target Bioclass
Other
Family
FAM169 family
Subcellular location
Nucleus envelope
Uniprot ID
Q9Y6X4
Ensemble ID
ENST00000389156.9
HGNC ID
HGNC:29138

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HCT15 SNV: p.A210V .
JURLMK1 SNV: p.D310H .
KARPAS422 SNV: p.L238F .
MEWO SNV: p.E388Ter DBIA    Probe Info 
NCIH1299 SNV: p.D193Y .
WM115 SNV: p.D193N .
WM2664 SNV: p.D193N DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 7 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
DBIA
 Probe Info  		C225(1.29)  LDD0531  [2]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [3]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [3]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [3]
W1
 Probe Info  		N.A.  LDD0236  [4]
AOyne
 Probe Info  		11.20  LDD0443  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C225(1.29)  LDD0531  [2]
 LDCM0215  AC10 PaTu 8988t C225(1.20)  LDD1094  [2]
 LDCM0216  AC100 HCT 116 C225(0.66)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C225(0.85)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C225(0.82)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C225(0.83)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C225(0.79)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C225(0.76)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C225(0.75)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C225(0.73)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C225(0.66)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C225(0.88)  LDD0542  [2]
 LDCM0226  AC11 PaTu 8988t C225(1.23)  LDD1105  [2]
 LDCM0227  AC110 HCT 116 C225(0.76)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C225(0.90)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C225(0.79)  LDD0546  [2]
 LDCM0237  AC12 PaTu 8988t C225(1.22)  LDD1116  [2]
 LDCM0246  AC128 HEK-293T C225(0.88)  LDD0844  [2]
 LDCM0247  AC129 HEK-293T C225(0.99)  LDD0845  [2]
 LDCM0249  AC130 HEK-293T C225(1.05)  LDD0847  [2]
 LDCM0250  AC131 HEK-293T C225(1.07)  LDD0848  [2]
 LDCM0251  AC132 HEK-293T C225(1.00)  LDD0849  [2]
 LDCM0252  AC133 HEK-293T C225(1.25)  LDD0850  [2]
 LDCM0253  AC134 HEK-293T C225(1.11)  LDD0851  [2]
 LDCM0254  AC135 HEK-293T C225(1.14)  LDD0852  [2]
 LDCM0255  AC136 HEK-293T C225(1.15)  LDD0853  [2]
 LDCM0256  AC137 HEK-293T C225(1.09)  LDD0854  [2]
 LDCM0257  AC138 HEK-293T C225(1.48)  LDD0855  [2]
 LDCM0258  AC139 HEK-293T C225(1.15)  LDD0856  [2]
 LDCM0259  AC14 PaTu 8988t C225(1.17)  LDD1138  [2]
 LDCM0260  AC140 HEK-293T C225(0.96)  LDD0858  [2]
 LDCM0261  AC141 HEK-293T C225(1.22)  LDD0859  [2]
 LDCM0262  AC142 HEK-293T C225(1.10)  LDD0860  [2]
 LDCM0263  AC143 HEK-293T C225(1.02)  LDD0861  [2]
 LDCM0264  AC144 HEK-293T C225(0.96)  LDD0862  [2]
 LDCM0265  AC145 HEK-293T C225(1.15)  LDD0863  [2]
 LDCM0266  AC146 HEK-293T C225(1.10)  LDD0864  [2]
 LDCM0267  AC147 HEK-293T C225(1.14)  LDD0865  [2]
 LDCM0268  AC148 HEK-293T C225(1.09)  LDD0866  [2]
 LDCM0269  AC149 HEK-293T C225(1.27)  LDD0867  [2]
 LDCM0270  AC15 PaTu 8988t C225(1.00)  LDD1149  [2]
 LDCM0271  AC150 HEK-293T C225(1.10)  LDD0869  [2]
 LDCM0272  AC151 HEK-293T C225(1.40)  LDD0870  [2]
 LDCM0273  AC152 HEK-293T C225(1.18)  LDD0871  [2]
 LDCM0274  AC153 HEK-293T C225(1.04)  LDD0872  [2]
 LDCM0621  AC154 HEK-293T C225(0.97)  LDD2162  [2]
 LDCM0622  AC155 HEK-293T C225(0.93)  LDD2163  [2]
 LDCM0623  AC156 HEK-293T C225(1.00)  LDD2164  [2]
 LDCM0624  AC157 HEK-293T C225(1.00)  LDD2165  [2]
 LDCM0276  AC17 HEK-293T C225(1.09)  LDD0874  [2]
 LDCM0277  AC18 HEK-293T C225(0.96)  LDD0875  [2]
 LDCM0278  AC19 HEK-293T C225(0.87)  LDD0876  [2]
 LDCM0279  AC2 HCT 116 C225(1.05)  LDD0596  [2]
 LDCM0280  AC20 HEK-293T C225(0.78)  LDD0878  [2]
 LDCM0281  AC21 HEK-293T C225(1.15)  LDD0879  [2]
 LDCM0282  AC22 HEK-293T C225(0.98)  LDD0880  [2]
 LDCM0283  AC23 HEK-293T C225(0.98)  LDD0881  [2]
 LDCM0284  AC24 HEK-293T C225(0.89)  LDD0882  [2]
 LDCM0285  AC25 HCT 116 C225(0.87)  LDD0602  [2]
 LDCM0286  AC26 HCT 116 C225(0.68)  LDD0603  [2]
 LDCM0287  AC27 HCT 116 C225(0.77)  LDD0604  [2]
 LDCM0288  AC28 HCT 116 C225(0.78)  LDD0605  [2]
 LDCM0289  AC29 HCT 116 C225(0.74)  LDD0606  [2]
 LDCM0290  AC3 HCT 116 C225(1.35)  LDD0607  [2]
 LDCM0291  AC30 HCT 116 C225(0.71)  LDD0608  [2]
 LDCM0292  AC31 HCT 116 C225(0.73)  LDD0609  [2]
 LDCM0293  AC32 HCT 116 C225(0.61)  LDD0610  [2]
 LDCM0294  AC33 HCT 116 C225(0.78)  LDD0611  [2]
 LDCM0295  AC34 HCT 116 C225(1.13)  LDD0612  [2]
 LDCM0296  AC35 HEK-293T C138(1.13); C225(0.96); C167(0.98)  LDD1535  [6]
 LDCM0297  AC36 HEK-293T C225(1.06); C167(1.12); C11(1.19)  LDD1536  [6]
 LDCM0298  AC37 HEK-293T C138(1.04); C225(1.18); C167(0.94)  LDD1537  [6]
 LDCM0299  AC38 HEK-293T C225(0.91); C167(1.06)  LDD1538  [6]
 LDCM0300  AC39 HEK-293T C225(0.96); C167(1.09)  LDD1539  [6]
 LDCM0301  AC4 HCT 116 C225(1.20)  LDD0618  [2]
 LDCM0302  AC40 HEK-293T C138(0.98); C225(0.99); C167(1.12)  LDD1541  [6]
 LDCM0303  AC41 HEK-293T C225(1.05); C167(1.08); C11(1.02)  LDD1542  [6]
 LDCM0304  AC42 HEK-293T C138(1.14); C225(0.99); C167(1.03); C11(1.50)  LDD1543  [6]
 LDCM0305  AC43 HEK-293T C138(1.11); C225(0.93); C167(0.95)  LDD1544  [6]
 LDCM0306  AC44 HEK-293T C225(1.05); C167(1.03); C11(0.95)  LDD1545  [6]
 LDCM0307  AC45 HEK-293T C138(1.01); C225(1.13); C167(1.00)  LDD1546  [6]
 LDCM0308  AC46 HEK-293T C225(0.91); C167(0.98)  LDD1547  [6]
 LDCM0309  AC47 HEK-293T C225(1.04); C167(1.11)  LDD1548  [6]
 LDCM0310  AC48 HEK-293T C138(1.09); C225(1.11); C167(1.10)  LDD1549  [6]
 LDCM0311  AC49 HEK-293T C225(0.97); C167(1.10); C11(1.23)  LDD1550  [6]
 LDCM0312  AC5 HCT 116 C225(1.37)  LDD0629  [2]
 LDCM0313  AC50 HEK-293T C138(1.01); C225(1.04); C167(1.04); C11(1.39)  LDD1552  [6]
 LDCM0314  AC51 HEK-293T C138(1.12); C225(1.02); C167(1.04)  LDD1553  [6]
 LDCM0315  AC52 HEK-293T C225(0.98); C167(0.93); C11(1.12)  LDD1554  [6]
 LDCM0316  AC53 HEK-293T C138(1.03); C225(1.10); C167(1.02)  LDD1555  [6]
 LDCM0317  AC54 HEK-293T C225(1.02); C167(1.05)  LDD1556  [6]
 LDCM0318  AC55 HEK-293T C225(0.98); C167(1.01)  LDD1557  [6]
 LDCM0319  AC56 HEK-293T C138(1.04); C225(1.03); C167(1.06)  LDD1558  [6]
 LDCM0320  AC57 HEK-293T C225(0.96); C167(1.10); C11(1.21)  LDD1559  [6]
 LDCM0321  AC58 HEK-293T C138(1.01); C225(1.00); C167(1.04); C11(1.06)  LDD1560  [6]
 LDCM0322  AC59 HEK-293T C138(1.07); C225(0.95); C167(1.08)  LDD1561  [6]
 LDCM0323  AC6 PaTu 8988t C225(1.05)  LDD1202  [2]
 LDCM0324  AC60 HEK-293T C225(1.02); C167(1.04); C11(1.29)  LDD1563  [6]
 LDCM0325  AC61 HEK-293T C138(0.97); C225(1.12); C167(1.05)  LDD1564  [6]
 LDCM0326  AC62 HEK-293T C225(1.00); C167(1.00)  LDD1565  [6]
 LDCM0327  AC63 HEK-293T C225(0.97); C167(1.08)  LDD1566  [6]
 LDCM0328  AC64 HEK-293T C138(1.02); C225(1.04); C167(1.08)  LDD1567  [6]
 LDCM0332  AC68 HCT 116 C225(1.41)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C225(1.46)  LDD0650  [2]
 LDCM0334  AC7 PaTu 8988t C225(1.03)  LDD1213  [2]
 LDCM0335  AC70 HCT 116 C225(1.05)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C225(1.40)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C225(1.03)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C225(0.89)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C225(1.48)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C225(1.15)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C225(1.21)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C225(1.56)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C225(1.16)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C225(1.13)  LDD0661  [2]
 LDCM0345  AC8 PaTu 8988t C225(1.01)  LDD1224  [2]
 LDCM0346  AC80 HCT 116 C225(0.92)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C225(1.16)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C225(1.03)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C225(0.89)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C225(0.86)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C225(0.83)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C225(0.88)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C225(1.00)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C225(0.89)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C225(1.08)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C225(1.21)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C225(1.07)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C225(1.03)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C225(1.03)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C225(1.01)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C225(0.93)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C225(0.95)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C225(1.08)  LDD0681  [2]
 LDCM0365  AC98 HCT 116 C225(0.76)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C225(0.70)  LDD0683  [2]
 LDCM0248  AKOS034007472 PaTu 8988t C225(1.20)  LDD1127  [2]
 LDCM0356  AKOS034007680 PaTu 8988t C225(1.11)  LDD1235  [2]
 LDCM0275  AKOS034007705 PaTu 8988t C225(1.01)  LDD1154  [2]
 LDCM0156  Aniline NCI-H1299 15.00  LDD0403  [1]
 LDCM0367  CL1 HCT 116 C225(1.05)  LDD0684  [2]
 LDCM0368  CL10 HCT 116 C225(1.08)  LDD0685  [2]
 LDCM0369  CL100 HCT 116 C225(1.05)  LDD0686  [2]
 LDCM0370  CL101 PaTu 8988t C225(1.00)  LDD1249  [2]
 LDCM0371  CL102 PaTu 8988t C225(1.11)  LDD1250  [2]
 LDCM0372  CL103 PaTu 8988t C225(1.30)  LDD1251  [2]
 LDCM0373  CL104 PaTu 8988t C225(1.17)  LDD1252  [2]
 LDCM0374  CL105 HEK-293T C225(1.14)  LDD0972  [2]
 LDCM0375  CL106 HEK-293T C225(0.90)  LDD0973  [2]
 LDCM0376  CL107 HEK-293T C225(1.00)  LDD0974  [2]
 LDCM0377  CL108 HEK-293T C225(0.92)  LDD0975  [2]
 LDCM0378  CL109 HEK-293T C225(0.80)  LDD0976  [2]
 LDCM0379  CL11 HCT 116 C225(1.17)  LDD0696  [2]
 LDCM0380  CL110 HEK-293T C225(0.92)  LDD0978  [2]
 LDCM0381  CL111 HEK-293T C225(0.84)  LDD0979  [2]
 LDCM0382  CL112 HCT 116 C225(0.83)  LDD0699  [2]
 LDCM0383  CL113 HCT 116 C225(0.83)  LDD0700  [2]
 LDCM0384  CL114 HCT 116 C225(1.00)  LDD0701  [2]
 LDCM0385  CL115 HCT 116 C225(1.00)  LDD0702  [2]
 LDCM0386  CL116 HCT 116 C225(0.93)  LDD0703  [2]
 LDCM0387  CL117 HEK-293T C138(1.06); C225(1.10); C167(0.95)  LDD1591  [6]
 LDCM0388  CL118 HEK-293T C138(1.06); C225(0.98); C167(1.00)  LDD1592  [6]
 LDCM0389  CL119 HEK-293T C138(1.16); C225(1.03); C167(1.06)  LDD1593  [6]
 LDCM0390  CL12 HCT 116 C225(1.20)  LDD0707  [2]
 LDCM0391  CL120 HEK-293T C225(1.03); C167(1.13); C11(0.99)  LDD1595  [6]
 LDCM0392  CL121 HEK-293T C138(0.99); C225(1.05); C167(0.99)  LDD1596  [6]
 LDCM0393  CL122 HEK-293T C138(1.02); C225(0.96); C167(0.90)  LDD1597  [6]
 LDCM0394  CL123 HEK-293T C138(1.08); C225(1.02); C167(0.98)  LDD1598  [6]
 LDCM0395  CL124 HEK-293T C225(1.23); C167(1.08); C11(1.15)  LDD1599  [6]
 LDCM0396  CL125 HEK-293T C138(0.86); C225(1.02); C167(1.19)  LDD1600  [6]
 LDCM0397  CL126 HEK-293T C138(0.87); C225(1.10); C167(0.93)  LDD1601  [6]
 LDCM0398  CL127 HEK-293T C138(0.94); C225(1.15); C167(1.07)  LDD1602  [6]
 LDCM0399  CL128 HEK-293T C225(1.09); C167(1.05); C11(0.92)  LDD1603  [6]
 LDCM0400  CL13 HCT 116 C225(1.06)  LDD0717  [2]
 LDCM0401  CL14 HCT 116 C225(1.11)  LDD0718  [2]
 LDCM0402  CL15 HCT 116 C225(0.98)  LDD0719  [2]
 LDCM0403  CL16 HCT 116 C225(0.97)  LDD0720  [2]
 LDCM0404  CL17 HCT 116 C225(0.67)  LDD0721  [2]
 LDCM0405  CL18 HCT 116 C225(0.78)  LDD0722  [2]
 LDCM0406  CL19 HCT 116 C225(0.71)  LDD0723  [2]
 LDCM0407  CL2 HCT 116 C225(0.98)  LDD0724  [2]
 LDCM0408  CL20 HCT 116 C225(0.72)  LDD0725  [2]
 LDCM0409  CL21 HCT 116 C225(0.69)  LDD0726  [2]
 LDCM0410  CL22 HCT 116 C225(1.17)  LDD0727  [2]
 LDCM0411  CL23 HCT 116 C225(1.01)  LDD0728  [2]
 LDCM0412  CL24 HCT 116 C225(0.81)  LDD0729  [2]
 LDCM0413  CL25 HCT 116 C225(0.79)  LDD0730  [2]
 LDCM0414  CL26 HCT 116 C225(0.81)  LDD0731  [2]
 LDCM0415  CL27 HCT 116 C225(0.75)  LDD0732  [2]
 LDCM0416  CL28 HCT 116 C225(0.75)  LDD0733  [2]
 LDCM0417  CL29 HCT 116 C225(0.94)  LDD0734  [2]
 LDCM0418  CL3 HCT 116 C225(1.21)  LDD0735  [2]
 LDCM0419  CL30 HCT 116 C225(1.15)  LDD0736  [2]
 LDCM0420  CL31 HCT 116 C225(0.79)  LDD0737  [2]
 LDCM0421  CL32 HEK-293T C225(0.96)  LDD1019  [2]
 LDCM0422  CL33 HEK-293T C225(0.89)  LDD1020  [2]
 LDCM0423  CL34 HEK-293T C225(1.02)  LDD1021  [2]
 LDCM0424  CL35 HEK-293T C225(0.98)  LDD1022  [2]
 LDCM0425  CL36 HEK-293T C225(0.92)  LDD1023  [2]
 LDCM0426  CL37 HEK-293T C225(1.00)  LDD1024  [2]
 LDCM0428  CL39 HEK-293T C225(1.17)  LDD1026  [2]
 LDCM0429  CL4 HCT 116 C225(0.97)  LDD0746  [2]
 LDCM0430  CL40 HEK-293T C225(1.07)  LDD1028  [2]
 LDCM0431  CL41 HEK-293T C225(1.06)  LDD1029  [2]
 LDCM0432  CL42 HEK-293T C225(1.22)  LDD1030  [2]
 LDCM0433  CL43 HEK-293T C225(1.27)  LDD1031  [2]
 LDCM0434  CL44 HEK-293T C225(1.17)  LDD1032  [2]
 LDCM0435  CL45 HEK-293T C225(1.06)  LDD1033  [2]
 LDCM0436  CL46 HEK-293T C225(0.96)  LDD1034  [2]
 LDCM0437  CL47 HEK-293T C225(1.00)  LDD1035  [2]
 LDCM0438  CL48 HEK-293T C225(0.93)  LDD1036  [2]
 LDCM0439  CL49 HEK-293T C225(1.03)  LDD1037  [2]
 LDCM0440  CL5 HCT 116 C225(0.97)  LDD0757  [2]
 LDCM0441  CL50 HEK-293T C225(0.92)  LDD1039  [2]
 LDCM0442  CL51 HEK-293T C225(0.94)  LDD1040  [2]
 LDCM0443  CL52 HEK-293T C225(1.15)  LDD1041  [2]
 LDCM0444  CL53 HEK-293T C225(1.07)  LDD1042  [2]
 LDCM0445  CL54 HEK-293T C225(1.12)  LDD1043  [2]
 LDCM0446  CL55 HEK-293T C225(1.43)  LDD1044  [2]
 LDCM0447  CL56 HEK-293T C225(0.97)  LDD1045  [2]
 LDCM0448  CL57 HEK-293T C225(0.73)  LDD1046  [2]
 LDCM0449  CL58 HEK-293T C225(0.84)  LDD1047  [2]
 LDCM0450  CL59 HEK-293T C225(0.96)  LDD1048  [2]
 LDCM0451  CL6 HCT 116 C225(0.89)  LDD0768  [2]
 LDCM0452  CL60 HEK-293T C225(1.04)  LDD1050  [2]
 LDCM0453  CL61 HCT 116 C225(0.91)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C225(0.95)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C225(0.81)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C225(0.86)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C225(0.97)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C225(0.86)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C225(1.04)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C225(1.18)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C225(0.86)  LDD0778  [2]
 LDCM0462  CL7 HCT 116 C225(1.01)  LDD0779  [2]
 LDCM0463  CL70 HCT 116 C225(0.87)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C225(1.00)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C225(0.92)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C225(2.19)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C225(1.37)  LDD0784  [2]
 LDCM0469  CL76 HEK-293T C225(1.11); C167(1.19); C11(1.11)  LDD1672  [6]
 LDCM0470  CL77 HEK-293T C225(1.05); C167(1.02); C11(1.45)  LDD1673  [6]
 LDCM0471  CL78 HEK-293T C138(1.04); C225(1.05); C167(1.02); C11(1.15)  LDD1674  [6]
 LDCM0472  CL79 HEK-293T C138(1.05); C225(0.94); C167(1.07)  LDD1675  [6]
 LDCM0473  CL8 HCT 116 C225(1.08)  LDD0790  [2]
 LDCM0474  CL80 HEK-293T C225(0.95); C167(0.96); C11(1.15)  LDD1677  [6]
 LDCM0475  CL81 HEK-293T C138(1.18); C225(1.06); C167(0.95)  LDD1678  [6]
 LDCM0476  CL82 HEK-293T C225(0.96); C167(0.93)  LDD1679  [6]
 LDCM0477  CL83 HEK-293T C225(0.97); C167(0.91)  LDD1680  [6]
 LDCM0478  CL84 HEK-293T C138(1.00); C225(1.01); C167(0.91)  LDD1681  [6]
 LDCM0479  CL85 HEK-293T C138(0.81); C225(1.15); C167(0.98)  LDD1682  [6]
 LDCM0480  CL86 HEK-293T C138(0.82); C225(1.08); C167(1.01)  LDD1683  [6]
 LDCM0481  CL87 HEK-293T C138(0.88); C225(1.01); C167(1.26)  LDD1684  [6]
 LDCM0482  CL88 HEK-293T C225(1.18); C167(1.17); C11(1.55)  LDD1685  [6]
 LDCM0483  CL89 HEK-293T C225(0.95); C167(1.11); C11(0.99)  LDD1686  [6]
 LDCM0484  CL9 HCT 116 C225(0.90)  LDD0801  [2]
 LDCM0485  CL90 HEK-293T C138(0.87); C225(1.11); C167(0.96); C11(1.03)  LDD1688  [6]
 LDCM0486  CL91 HCT 116 C225(1.25)  LDD0803  [2]
 LDCM0487  CL92 HCT 116 C225(1.14)  LDD0804  [2]
 LDCM0488  CL93 HCT 116 C225(1.26)  LDD0805  [2]
 LDCM0489  CL94 HCT 116 C225(1.09)  LDD0806  [2]
 LDCM0490  CL95 HCT 116 C225(1.14)  LDD0807  [2]
 LDCM0491  CL96 HCT 116 C225(1.33)  LDD0808  [2]
 LDCM0492  CL97 HCT 116 C225(1.15)  LDD0809  [2]
 LDCM0493  CL98 HCT 116 C225(1.04)  LDD0810  [2]
 LDCM0494  CL99 HCT 116 C225(1.08)  LDD0811  [2]
 LDCM0495  E2913 HEK-293T C138(1.58); C225(1.00); C167(1.19)  LDD1698  [6]
 LDCM0468  Fragment33 HCT 116 C225(0.95)  LDD0785  [2]
 LDCM0427  Fragment51 HEK-293T C225(1.01)  LDD1025  [2]
 LDCM0022  KB02 HEK-293T C138(1.12); C225(1.02); C167(1.01)  LDD1492  [6]
 LDCM0023  KB03 HEK-293T C138(1.03); C225(1.04); C167(0.97)  LDD1497  [6]
 LDCM0024  KB05 Hs 936.T C225(3.46)  LDD3313  [7]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Myotubularin-related protein 9 (MTMR9) Protein-tyrosine phosphatase family Q96QG7
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Lamin-B1 (LMNB1) Intermediate filament family P20700

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
4 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
5 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
6 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
7 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840