Details of the Target

General Information of Target

Target ID LDTP16976
Target Name RWD domain-containing protein 2B (RWDD2B)
Gene Name RWDD2B
Gene ID 10069
Synonyms
C21orf6; RWD domain-containing protein 2B
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGCRDVHAATVLSFLCGIASVAGLFAGTLLPNWRKLRLITFNRNEKNLTVYTGLWVKCAR
YDGSSDCLMYDTTWYSSVDQLDLRVLQFALPLSMLIAMGALLLCLIGMCNTAFRSSVPNI
KLAKCLVNSAGCHLVAGLLFFLAGTVSLSPSIWVIFYNIHLNKKFEPVFSFDYAVYVTIA
SAGGLFMTSLILFIWYCTCKSLPSPFWQPLYSHPPSMHTYSQPYSARSRLSAIEIDIPVV
SHTT
Target Bioclass
Enzyme
Uniprot ID
P57060
Ensemble ID
ENST00000493196.2
HGNC ID
HGNC:1302

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C228(0.80); C236(0.80)  LDD0532  [1]
IA-alkyne
 Probe Info  		C181(0.00); C2940, C2404, C4539, C3471, C4005(0.00)  LDD0161  [2]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [3]
NAIA_5
 Probe Info  		N.A.  LDD2223  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C236(0.97)  LDD0812  [1]
 LDCM0215  AC10 HCT 116 C228(0.80); C236(0.80)  LDD0532  [1]
 LDCM0216  AC100 HCT 116 C145(1.21); C150(1.21)  LDD0533  [1]
 LDCM0217  AC101 HCT 116 C145(1.03); C150(1.03)  LDD0534  [1]
 LDCM0218  AC102 HCT 116 C145(1.05); C150(1.05)  LDD0535  [1]
 LDCM0219  AC103 HCT 116 C145(1.07); C150(1.07)  LDD0536  [1]
 LDCM0220  AC104 HCT 116 C145(1.13); C150(1.13)  LDD0537  [1]
 LDCM0221  AC105 HCT 116 C145(1.10); C150(1.10)  LDD0538  [1]
 LDCM0222  AC106 HCT 116 C145(1.15); C150(1.15)  LDD0539  [1]
 LDCM0223  AC107 HCT 116 C145(0.94); C150(0.94)  LDD0540  [1]
 LDCM0224  AC108 HCT 116 C145(1.21); C150(1.21)  LDD0541  [1]
 LDCM0225  AC109 HCT 116 C145(0.99); C150(0.99)  LDD0542  [1]
 LDCM0226  AC11 HCT 116 C228(0.98); C236(0.98)  LDD0543  [1]
 LDCM0227  AC110 HCT 116 C145(0.92); C150(0.92)  LDD0544  [1]
 LDCM0228  AC111 HCT 116 C145(1.11); C150(1.11)  LDD0545  [1]
 LDCM0229  AC112 HCT 116 C145(0.98); C150(0.98)  LDD0546  [1]
 LDCM0230  AC113 HCT 116 C145(1.17); C150(1.17)  LDD0547  [1]
 LDCM0231  AC114 HCT 116 C145(1.08); C150(0.87)  LDD0548  [1]
 LDCM0232  AC115 HCT 116 C145(0.98); C150(1.13)  LDD0549  [1]
 LDCM0233  AC116 HCT 116 C145(1.16); C150(1.14)  LDD0550  [1]
 LDCM0234  AC117 HCT 116 C145(1.03); C150(1.42)  LDD0551  [1]
 LDCM0235  AC118 HCT 116 C145(1.01); C150(1.12)  LDD0552  [1]
 LDCM0236  AC119 HCT 116 C145(1.01); C150(1.11)  LDD0553  [1]
 LDCM0237  AC12 HCT 116 C228(1.32); C236(1.32)  LDD0554  [1]
 LDCM0238  AC120 HCT 116 C145(1.19); C150(0.92)  LDD0555  [1]
 LDCM0239  AC121 HCT 116 C145(1.21); C150(1.54)  LDD0556  [1]
 LDCM0240  AC122 HCT 116 C145(1.09); C150(1.06)  LDD0557  [1]
 LDCM0241  AC123 HCT 116 C145(1.06); C150(1.86)  LDD0558  [1]
 LDCM0242  AC124 HCT 116 C145(1.25); C150(1.18)  LDD0559  [1]
 LDCM0243  AC125 HCT 116 C145(1.21); C150(0.95)  LDD0560  [1]
 LDCM0244  AC126 HCT 116 C145(1.18); C150(1.01)  LDD0561  [1]
 LDCM0245  AC127 HCT 116 C145(1.23); C150(1.03)  LDD0562  [1]
 LDCM0259  AC14 HCT 116 C228(0.87); C236(0.87)  LDD0576  [1]
 LDCM0263  AC143 HEK-293T C145(1.10); C228(0.62); C236(0.62)  LDD0861  [1]
 LDCM0264  AC144 HEK-293T C145(0.96); C228(0.96); C236(0.96)  LDD0862  [1]
 LDCM0265  AC145 HEK-293T C145(0.82); C228(0.60); C236(0.60)  LDD0863  [1]
 LDCM0266  AC146 HEK-293T C145(0.91); C228(0.61); C236(0.61)  LDD0864  [1]
 LDCM0267  AC147 HEK-293T C145(0.98); C228(0.63); C236(0.63)  LDD0865  [1]
 LDCM0268  AC148 HEK-293T C145(0.88); C228(0.49); C236(0.49)  LDD0866  [1]
 LDCM0269  AC149 HEK-293T C145(0.94); C228(1.08); C236(1.08)  LDD0867  [1]
 LDCM0270  AC15 HCT 116 C228(0.82); C236(0.82)  LDD0587  [1]
 LDCM0271  AC150 HEK-293T C145(1.00); C228(0.65); C236(0.65)  LDD0869  [1]
 LDCM0272  AC151 HEK-293T C145(0.81); C228(0.74); C236(0.74)  LDD0870  [1]
 LDCM0273  AC152 HEK-293T C145(0.97); C228(0.88); C236(0.88)  LDD0871  [1]
 LDCM0274  AC153 HEK-293T C145(1.06); C228(1.01); C236(1.01)  LDD0872  [1]
 LDCM0621  AC154 HEK-293T C145(1.06); C228(0.85); C236(0.85)  LDD2162  [1]
 LDCM0622  AC155 HEK-293T C145(0.92); C228(0.81); C236(0.81)  LDD2163  [1]
 LDCM0623  AC156 HEK-293T C145(0.87); C228(0.85); C236(0.85)  LDD2164  [1]
 LDCM0624  AC157 HEK-293T C145(1.07); C228(0.99); C236(0.99)  LDD2165  [1]
 LDCM0276  AC17 HEK-293T C228(0.77); C236(0.90)  LDD0874  [1]
 LDCM0277  AC18 HEK-293T C228(0.86); C236(0.92)  LDD0875  [1]
 LDCM0278  AC19 HEK-293T C228(0.92); C236(0.90)  LDD0876  [1]
 LDCM0279  AC2 HEK-293T C236(1.29)  LDD0877  [1]
 LDCM0280  AC20 HEK-293T C228(0.99); C236(1.13)  LDD0878  [1]
 LDCM0281  AC21 HEK-293T C228(1.45); C236(1.50)  LDD0879  [1]
 LDCM0282  AC22 HEK-293T C228(1.01); C236(1.18)  LDD0880  [1]
 LDCM0283  AC23 HEK-293T C228(1.16); C236(1.25)  LDD0881  [1]
 LDCM0284  AC24 HEK-293T C228(1.24); C236(1.34)  LDD0882  [1]
 LDCM0285  AC25 HCT 116 C228(0.42); C236(0.42)  LDD0602  [1]
 LDCM0286  AC26 HCT 116 C228(0.47); C236(0.47)  LDD0603  [1]
 LDCM0287  AC27 HCT 116 C228(0.54); C236(0.54)  LDD0604  [1]
 LDCM0288  AC28 HCT 116 C228(0.43); C236(0.43)  LDD0605  [1]
 LDCM0289  AC29 HCT 116 C228(0.58); C236(0.58)  LDD0606  [1]
 LDCM0290  AC3 HEK-293T C236(1.38)  LDD0888  [1]
 LDCM0291  AC30 HCT 116 C228(0.39); C236(0.39)  LDD0608  [1]
 LDCM0292  AC31 HCT 116 C228(0.53); C236(0.53)  LDD0609  [1]
 LDCM0293  AC32 HCT 116 C228(0.54); C236(0.54)  LDD0610  [1]
 LDCM0294  AC33 HCT 116 C228(0.52); C236(0.52)  LDD0611  [1]
 LDCM0295  AC34 HCT 116 C228(0.47); C236(0.47)  LDD0612  [1]
 LDCM0296  AC35 HCT 116 C228(0.82); C236(0.82)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C228(0.72); C236(0.72)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C228(0.56); C236(0.56)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C228(0.57); C236(0.57)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C228(0.98); C236(0.98)  LDD0617  [1]
 LDCM0301  AC4 HEK-293T C236(1.40)  LDD0899  [1]
 LDCM0302  AC40 HCT 116 C228(0.53); C236(0.53)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C228(0.54); C236(0.54)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C228(0.43); C236(0.43)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C228(0.50); C236(0.50)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C228(0.54); C236(0.54)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C228(0.47); C236(0.47)  LDD0624  [1]
 LDCM0308  AC46 HCT 116 C145(1.04); C150(1.04)  LDD0625  [1]
 LDCM0309  AC47 HCT 116 C145(1.05); C150(1.05)  LDD0626  [1]
 LDCM0310  AC48 HCT 116 C145(0.71); C150(0.71)  LDD0627  [1]
 LDCM0311  AC49 HCT 116 C145(2.88); C150(2.88)  LDD0628  [1]
 LDCM0312  AC5 HEK-293T C236(1.21)  LDD0910  [1]
 LDCM0313  AC50 HCT 116 C145(0.86); C150(0.86)  LDD0630  [1]
 LDCM0314  AC51 HCT 116 C145(1.24); C150(1.24)  LDD0631  [1]
 LDCM0315  AC52 HCT 116 C145(1.35); C150(1.35)  LDD0632  [1]
 LDCM0316  AC53 HCT 116 C145(0.98); C150(0.98)  LDD0633  [1]
 LDCM0317  AC54 HCT 116 C145(1.00); C150(1.00)  LDD0634  [1]
 LDCM0318  AC55 HCT 116 C145(0.81); C150(0.81)  LDD0635  [1]
 LDCM0319  AC56 HCT 116 C145(0.89); C150(0.89)  LDD0636  [1]
 LDCM0320  AC57 HEK-293T C145(1.21); C228(1.04); C236(0.87)  LDD0918  [1]
 LDCM0321  AC58 HEK-293T C145(0.98); C228(1.04); C236(0.80)  LDD0919  [1]
 LDCM0322  AC59 HEK-293T C145(0.93); C228(1.31); C236(0.93)  LDD0920  [1]
 LDCM0323  AC6 HCT 116 C228(0.81); C236(0.81)  LDD0640  [1]
 LDCM0324  AC60 HEK-293T C145(0.69); C228(0.77); C236(0.84)  LDD0922  [1]
 LDCM0325  AC61 HEK-293T C145(0.96); C228(0.78); C236(0.90)  LDD0923  [1]
 LDCM0326  AC62 HEK-293T C145(0.70); C228(1.24); C236(0.92)  LDD0924  [1]
 LDCM0327  AC63 HEK-293T C145(0.86); C228(1.19); C236(0.96)  LDD0925  [1]
 LDCM0328  AC64 HEK-293T C145(0.87); C228(1.28); C236(0.73)  LDD0926  [1]
 LDCM0329  AC65 HEK-293T C145(0.81); C228(1.11); C236(0.93)  LDD0927  [1]
 LDCM0330  AC66 HEK-293T C145(0.78); C228(1.21); C236(1.06)  LDD0928  [1]
 LDCM0331  AC67 HEK-293T C145(0.98); C228(1.05); C236(0.89)  LDD0929  [1]
 LDCM0332  AC68 HCT 116 C145(0.83); C150(0.83)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C145(0.77); C150(0.77)  LDD0650  [1]
 LDCM0334  AC7 HCT 116 C228(1.07); C236(1.07)  LDD0651  [1]
 LDCM0335  AC70 HCT 116 C145(1.69); C150(1.69)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C145(1.12); C150(1.12)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C145(0.83); C150(0.83)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C145(0.98); C150(0.98)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C145(0.94); C150(0.94)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C145(1.04); C150(1.04)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C145(1.02); C150(1.02)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C145(0.72); C150(0.72)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C145(0.73); C150(0.73)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C145(1.10); C150(1.10)  LDD0661  [1]
 LDCM0345  AC8 HCT 116 C228(1.02); C236(1.02)  LDD0662  [1]
 LDCM0346  AC80 HCT 116 C145(0.94); C150(0.94)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C145(0.82); C150(0.82)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C145(1.15); C150(1.15)  LDD0665  [1]
 LDCM0349  AC83 HEK-293T C145(1.46); C228(1.51); C236(1.31)  LDD0947  [1]
 LDCM0350  AC84 HEK-293T C145(1.26); C228(1.49); C236(1.26)  LDD0948  [1]
 LDCM0351  AC85 HEK-293T C145(1.15); C228(0.93); C236(1.11)  LDD0949  [1]
 LDCM0352  AC86 HEK-293T C145(1.23); C228(0.98); C236(1.12)  LDD0950  [1]
 LDCM0353  AC87 HEK-293T C145(0.98); C228(1.33); C236(1.20)  LDD0951  [1]
 LDCM0354  AC88 HEK-293T C145(0.83); C228(0.67); C236(0.80)  LDD0952  [1]
 LDCM0355  AC89 HEK-293T C145(1.04); C228(1.44); C236(1.25)  LDD0953  [1]
 LDCM0357  AC90 HEK-293T C145(1.58); C228(1.02); C236(1.02)  LDD0955  [1]
 LDCM0358  AC91 HEK-293T C145(0.97); C228(1.68); C236(1.34)  LDD0956  [1]
 LDCM0359  AC92 HEK-293T C145(1.14); C228(1.49); C236(1.26)  LDD0957  [1]
 LDCM0360  AC93 HEK-293T C145(0.89); C228(2.02); C236(1.57)  LDD0958  [1]
 LDCM0361  AC94 HEK-293T C145(0.87); C228(2.32); C236(1.79)  LDD0959  [1]
 LDCM0362  AC95 HEK-293T C145(1.63); C228(2.02); C236(1.68)  LDD0960  [1]
 LDCM0363  AC96 HEK-293T C145(1.70); C228(1.88); C236(1.51)  LDD0961  [1]
 LDCM0364  AC97 HEK-293T C145(0.18); C228(2.02); C236(1.79)  LDD0962  [1]
 LDCM0365  AC98 HCT 116 C145(1.03); C150(1.03)  LDD0682  [1]
 LDCM0366  AC99 HCT 116 C145(1.12); C150(1.12)  LDD0683  [1]
 LDCM0248  AKOS034007472 HCT 116 C228(1.04); C236(1.04)  LDD0565  [1]
 LDCM0356  AKOS034007680 HCT 116 C228(0.85); C236(0.85)  LDD0673  [1]
 LDCM0275  AKOS034007705 HCT 116 C228(0.66); C236(0.66)  LDD0592  [1]
 LDCM0367  CL1 HCT 116 C228(1.15); C236(1.15)  LDD0684  [1]
 LDCM0368  CL10 HCT 116 C228(1.78); C236(1.78)  LDD0685  [1]
 LDCM0369  CL100 HEK-293T C236(1.39)  LDD0967  [1]
 LDCM0370  CL101 HCT 116 C228(0.76); C236(0.76)  LDD0687  [1]
 LDCM0371  CL102 HCT 116 C228(0.90); C236(0.90)  LDD0688  [1]
 LDCM0372  CL103 HCT 116 C228(0.90); C236(0.90)  LDD0689  [1]
 LDCM0373  CL104 HCT 116 C228(1.09); C236(1.09)  LDD0690  [1]
 LDCM0374  CL105 HEK-293T C228(0.88); C236(1.02)  LDD0972  [1]
 LDCM0375  CL106 HEK-293T C228(0.88); C236(0.99)  LDD0973  [1]
 LDCM0376  CL107 HEK-293T C228(1.02); C236(0.97)  LDD0974  [1]
 LDCM0377  CL108 HEK-293T C228(0.86); C236(0.92)  LDD0975  [1]
 LDCM0378  CL109 HEK-293T C228(1.00); C236(1.08)  LDD0976  [1]
 LDCM0379  CL11 HCT 116 C228(2.33); C236(2.33)  LDD0696  [1]
 LDCM0380  CL110 HEK-293T C228(1.01); C236(1.02)  LDD0978  [1]
 LDCM0381  CL111 HEK-293T C228(1.11); C236(1.10)  LDD0979  [1]
 LDCM0382  CL112 HCT 116 C228(0.43); C236(0.43)  LDD0699  [1]
 LDCM0383  CL113 HCT 116 C228(0.57); C236(0.57)  LDD0700  [1]
 LDCM0384  CL114 HCT 116 C228(0.42); C236(0.42)  LDD0701  [1]
 LDCM0385  CL115 HCT 116 C228(0.35); C236(0.35)  LDD0702  [1]
 LDCM0386  CL116 HCT 116 C228(0.51); C236(0.51)  LDD0703  [1]
 LDCM0387  CL117 HCT 116 C228(0.37); C236(0.37)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C228(0.81); C236(0.81)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C228(0.98); C236(0.98)  LDD0706  [1]
 LDCM0390  CL12 HCT 116 C228(2.52); C236(2.52)  LDD0707  [1]
 LDCM0391  CL120 HCT 116 C228(0.76); C236(0.76)  LDD0708  [1]
 LDCM0392  CL121 HCT 116 C145(4.35); C150(4.35)  LDD0709  [1]
 LDCM0393  CL122 HCT 116 C145(0.91); C150(0.91)  LDD0710  [1]
 LDCM0394  CL123 HCT 116 C145(0.85); C150(0.85)  LDD0711  [1]
 LDCM0395  CL124 HCT 116 C145(0.90); C150(0.90)  LDD0712  [1]
 LDCM0396  CL125 HEK-293T C145(0.82); C228(0.95); C236(1.03)  LDD0994  [1]
 LDCM0397  CL126 HEK-293T C145(0.77); C228(0.97); C236(0.94)  LDD0995  [1]
 LDCM0398  CL127 HEK-293T C145(0.74); C228(1.10); C236(1.18)  LDD0996  [1]
 LDCM0399  CL128 HEK-293T C145(0.96); C228(1.06); C236(1.00)  LDD0997  [1]
 LDCM0400  CL13 HCT 116 C228(1.54); C236(1.54)  LDD0717  [1]
 LDCM0401  CL14 HCT 116 C228(1.70); C236(1.70)  LDD0718  [1]
 LDCM0402  CL15 HCT 116 C228(1.54); C236(1.54)  LDD0719  [1]
 LDCM0403  CL16 HEK-293T C145(0.87)  LDD1001  [1]
 LDCM0404  CL17 HEK-293T C145(0.73)  LDD1002  [1]
 LDCM0405  CL18 HEK-293T C145(2.22)  LDD1003  [1]
 LDCM0406  CL19 HEK-293T C145(1.07)  LDD1004  [1]
 LDCM0407  CL2 HCT 116 C228(1.55); C236(1.55)  LDD0724  [1]
 LDCM0408  CL20 HEK-293T C145(0.91)  LDD1006  [1]
 LDCM0409  CL21 HEK-293T C145(0.66)  LDD1007  [1]
 LDCM0410  CL22 HEK-293T C145(0.84)  LDD1008  [1]
 LDCM0411  CL23 HEK-293T C145(0.76)  LDD1009  [1]
 LDCM0412  CL24 HEK-293T C145(1.36)  LDD1010  [1]
 LDCM0413  CL25 HEK-293T C145(0.56)  LDD1011  [1]
 LDCM0414  CL26 HEK-293T C145(0.88)  LDD1012  [1]
 LDCM0415  CL27 HEK-293T C145(0.94)  LDD1013  [1]
 LDCM0416  CL28 HEK-293T C145(0.68)  LDD1014  [1]
 LDCM0417  CL29 HEK-293T C145(1.16)  LDD1015  [1]
 LDCM0418  CL3 HCT 116 C228(1.43); C236(1.43)  LDD0735  [1]
 LDCM0419  CL30 HEK-293T C145(0.73)  LDD1017  [1]
 LDCM0420  CL31 HEK-293T C145(1.12)  LDD1018  [1]
 LDCM0421  CL32 HEK-293T C145(3.19)  LDD1019  [1]
 LDCM0422  CL33 HEK-293T C145(0.88)  LDD1020  [1]
 LDCM0423  CL34 HEK-293T C145(1.18)  LDD1021  [1]
 LDCM0424  CL35 HEK-293T C145(1.13)  LDD1022  [1]
 LDCM0425  CL36 HEK-293T C145(1.13)  LDD1023  [1]
 LDCM0426  CL37 HEK-293T C145(1.15)  LDD1024  [1]
 LDCM0428  CL39 HEK-293T C145(0.90)  LDD1026  [1]
 LDCM0429  CL4 HCT 116 C228(1.33); C236(1.33)  LDD0746  [1]
 LDCM0430  CL40 HEK-293T C145(0.97)  LDD1028  [1]
 LDCM0431  CL41 HEK-293T C145(1.02)  LDD1029  [1]
 LDCM0432  CL42 HEK-293T C145(0.94)  LDD1030  [1]
 LDCM0433  CL43 HEK-293T C145(1.10)  LDD1031  [1]
 LDCM0434  CL44 HEK-293T C145(1.61)  LDD1032  [1]
 LDCM0435  CL45 HEK-293T C145(1.13)  LDD1033  [1]
 LDCM0436  CL46 HEK-293T C145(0.91)  LDD1034  [1]
 LDCM0437  CL47 HEK-293T C145(1.24)  LDD1035  [1]
 LDCM0438  CL48 HEK-293T C145(1.59)  LDD1036  [1]
 LDCM0439  CL49 HEK-293T C145(0.63)  LDD1037  [1]
 LDCM0440  CL5 HCT 116 C228(1.59); C236(1.59)  LDD0757  [1]
 LDCM0441  CL50 HEK-293T C145(0.49)  LDD1039  [1]
 LDCM0442  CL51 HEK-293T C145(0.84)  LDD1040  [1]
 LDCM0443  CL52 HEK-293T C145(0.69)  LDD1041  [1]
 LDCM0444  CL53 HEK-293T C145(0.49)  LDD1042  [1]
 LDCM0445  CL54 HEK-293T C145(0.66)  LDD1043  [1]
 LDCM0446  CL55 HEK-293T C145(0.91)  LDD1044  [1]
 LDCM0447  CL56 HEK-293T C145(0.43)  LDD1045  [1]
 LDCM0448  CL57 HEK-293T C145(0.75)  LDD1046  [1]
 LDCM0449  CL58 HEK-293T C145(1.20)  LDD1047  [1]
 LDCM0450  CL59 HEK-293T C145(0.68)  LDD1048  [1]
 LDCM0451  CL6 HCT 116 C228(1.62); C236(1.62)  LDD0768  [1]
 LDCM0452  CL60 HEK-293T C145(0.66)  LDD1050  [1]
 LDCM0462  CL7 HCT 116 C228(1.64); C236(1.64)  LDD0779  [1]
 LDCM0473  CL8 HCT 116 C228(1.62); C236(1.62)  LDD0790  [1]
 LDCM0484  CL9 HCT 116 C228(1.25); C236(1.25)  LDD0801  [1]
 LDCM0486  CL91 HEK-293T C236(1.15)  LDD1084  [1]
 LDCM0487  CL92 HEK-293T C236(1.29)  LDD1085  [1]
 LDCM0488  CL93 HEK-293T C236(1.05)  LDD1086  [1]
 LDCM0489  CL94 HEK-293T C236(1.27)  LDD1087  [1]
 LDCM0490  CL95 HEK-293T C236(1.24)  LDD1088  [1]
 LDCM0491  CL96 HEK-293T C236(1.25)  LDD1089  [1]
 LDCM0492  CL97 HEK-293T C236(1.37)  LDD1090  [1]
 LDCM0493  CL98 HEK-293T C236(1.32)  LDD1091  [1]
 LDCM0494  CL99 HEK-293T C236(1.22)  LDD1092  [1]
 LDCM0427  Fragment51 HEK-293T C145(1.59)  LDD1025  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
E3 ubiquitin-protein ligase TRIM7 (TRIM7) TRIM/RBCC family Q9C029
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
DNA-binding protein Ikaros (IKZF1) Ikaros C2H2-type zinc-finger protein family Q13422
Other
Click To Hide/Show 7 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Segment polarity protein dishevelled homolog DVL-3 (DVL3) DSH family Q92997
Protein FAM163A (FAM163A) FAM163 family Q96GL9
Growth arrest and DNA damage-inducible protein GADD45 gamma (GADD45G) GADD45 family O95257
Keratin, type I cytoskeletal 40 (KRT40) Intermediate filament family Q6A162
Keratin-associated protein 10-7 (KRTAP10-7) KRTAP type 10 family P60409
Polyhomeotic-like protein 2 (PHC2) . Q8IXK0
Uncharacterized protein KIAA1958 (KIAA1958) . Q8N8K9

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
3 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
4 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264