Details of the Target

General Information of Target

Target ID LDTP14647
Target Name Zinc finger protein 7 (ZNF7)
Gene Name ZNF7
Gene ID 7553
Synonyms
KOX4; Zinc finger protein 7; Zinc finger protein HF.16; Zinc finger protein KOX4
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAHKYVGLQYHGSVTFEDVAIAFSQQEWESLDSSQRGLYRDVMLENYRNLVSMGHSRSKP
HVIALLEQWKEPEVTVRKDGRRWCTDLQLEDDTIGCKEMPTSENCPSFALHQKISRQKPR
ECQEYGKTLCQDSKPVQHERIHSSEKPNRCKECGKNFSNGHQLTIHQRLHVGEKPYKYEK
CGKAFISGSAFVKHGRIHTGEKPLKCKQCGKTISGSYQLTVHKSIHTGKKPYECGECGKA
FLVYGKLTRHQSTHTGEKPFGCEECGKAFSTFSYLVQHQRIHTSEKPYECKECGKAFSTS
SPLAKHQRIHTGEKPYECKECGKSFTVYGQLTRHQSIHTGEKPFECKECGKAFRLSSFLH
AHQRIHAEIKPYGCKECGRTFSRASYLVQHGRLHTGEKPYECKECGKAFSTGSYLVQHQR
IHTGEKPYECKECGKAFISRHQLTVHQRVHTGEKPYECKECGKAFRVHVHLTQHRKIHTD
VKPYECKECGKTFSRASYLVQHSRIHTGKKPYECKECGKAFSSGSYLVQHQRIHTGEKPY
ECNKCGKAFTVYGQLIGHQSVHTGEKPFECKECGKAFRLNSFLTEHQRVHTGEKPFKCKK
CGKTFRYSSALKVHLRKHMSVIP
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
P17097
Ensemble ID
ENST00000446747.7
HGNC ID
HGNC:13139

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
769P SNV: p.G613W .
DU145 Insertion: p.E359GfsTer56 DBIA    Probe Info 
HCT116 Deletion: p.K231SfsTer59 DBIA    Probe Info 
TE4 Deletion: p.C152Ter DBIA    Probe Info 
TOV21G Insertion: p.L232VfsTer3 DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C452(40.16)  LDD0209  [1]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [2]
IPM
 Probe Info  		N.A.  LDD0147  [3]
HHS-465
 Probe Info  		K439(0.00); K442(0.00); Y441(0.00)  LDD2240  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C171(1.07); C452(1.20)  LDD0531  [5]
 LDCM0215  AC10 HCT 116 C452(1.46)  LDD0532  [5]
 LDCM0216  AC100 HCT 116 C452(0.86)  LDD0533  [5]
 LDCM0217  AC101 HCT 116 C452(0.92)  LDD0534  [5]
 LDCM0218  AC102 HCT 116 C452(0.90)  LDD0535  [5]
 LDCM0219  AC103 HCT 116 C452(0.99)  LDD0536  [5]
 LDCM0220  AC104 HCT 116 C452(0.88)  LDD0537  [5]
 LDCM0221  AC105 HCT 116 C452(0.67)  LDD0538  [5]
 LDCM0222  AC106 HCT 116 C452(1.02)  LDD0539  [5]
 LDCM0223  AC107 HCT 116 C452(1.10)  LDD0540  [5]
 LDCM0224  AC108 HCT 116 C452(0.81)  LDD0541  [5]
 LDCM0225  AC109 HCT 116 C452(0.68)  LDD0542  [5]
 LDCM0226  AC11 HCT 116 C452(1.69)  LDD0543  [5]
 LDCM0227  AC110 HCT 116 C452(0.91)  LDD0544  [5]
 LDCM0228  AC111 HCT 116 C452(1.11)  LDD0545  [5]
 LDCM0229  AC112 HCT 116 C452(0.92)  LDD0546  [5]
 LDCM0230  AC113 HCT 116 C171(0.98); C452(0.79); C636(0.83); C639(0.83)  LDD0547  [5]
 LDCM0231  AC114 HCT 116 C171(1.11); C452(0.89); C636(0.92); C639(0.86)  LDD0548  [5]
 LDCM0232  AC115 HCT 116 C171(1.16); C452(0.96); C636(0.78); C639(0.91)  LDD0549  [5]
 LDCM0233  AC116 HCT 116 C171(1.31); C452(0.86); C636(1.04); C639(0.90)  LDD0550  [5]
 LDCM0234  AC117 HCT 116 C171(1.05); C452(1.09); C636(1.00); C639(1.07)  LDD0551  [5]
 LDCM0235  AC118 HCT 116 C171(1.00); C452(0.79); C636(0.91); C639(0.94)  LDD0552  [5]
 LDCM0236  AC119 HCT 116 C171(1.27); C452(0.89); C636(0.99); C639(1.03)  LDD0553  [5]
 LDCM0237  AC12 HCT 116 C452(1.29)  LDD0554  [5]
 LDCM0238  AC120 HCT 116 C171(1.12); C452(0.83); C636(1.03); C639(0.89)  LDD0555  [5]
 LDCM0239  AC121 HCT 116 C171(0.95); C452(0.94); C636(0.68); C639(0.99)  LDD0556  [5]
 LDCM0240  AC122 HCT 116 C171(1.02); C452(1.14); C636(0.90); C639(0.93)  LDD0557  [5]
 LDCM0241  AC123 HCT 116 C171(0.94); C452(0.92); C636(0.68); C639(0.80)  LDD0558  [5]
 LDCM0242  AC124 HCT 116 C171(1.17); C452(0.80); C636(0.93); C639(1.06)  LDD0559  [5]
 LDCM0243  AC125 HCT 116 C171(1.05); C452(0.77); C636(1.09); C639(0.75)  LDD0560  [5]
 LDCM0244  AC126 HCT 116 C171(1.14); C452(1.13); C636(1.12); C639(0.85)  LDD0561  [5]
 LDCM0245  AC127 HCT 116 C171(1.25); C452(1.05); C636(0.82); C639(0.82)  LDD0562  [5]
 LDCM0246  AC128 HCT 116 C452(0.80)  LDD0563  [5]
 LDCM0247  AC129 HCT 116 C452(0.83)  LDD0564  [5]
 LDCM0249  AC130 HCT 116 C452(0.84)  LDD0566  [5]
 LDCM0250  AC131 HCT 116 C452(1.41)  LDD0567  [5]
 LDCM0251  AC132 HCT 116 C452(0.74)  LDD0568  [5]
 LDCM0252  AC133 HCT 116 C452(0.84)  LDD0569  [5]
 LDCM0253  AC134 HCT 116 C452(0.83)  LDD0570  [5]
 LDCM0254  AC135 HCT 116 C452(0.75)  LDD0571  [5]
 LDCM0255  AC136 HCT 116 C452(1.10)  LDD0572  [5]
 LDCM0256  AC137 HCT 116 C452(0.95)  LDD0573  [5]
 LDCM0257  AC138 HCT 116 C452(1.14)  LDD0574  [5]
 LDCM0258  AC139 HCT 116 C452(1.26)  LDD0575  [5]
 LDCM0259  AC14 HCT 116 C452(1.35)  LDD0576  [5]
 LDCM0260  AC140 HCT 116 C452(1.10)  LDD0577  [5]
 LDCM0261  AC141 HCT 116 C452(1.40)  LDD0578  [5]
 LDCM0262  AC142 HCT 116 C452(0.69)  LDD0579  [5]
 LDCM0263  AC143 HCT 116 C452(0.94); C171(1.48)  LDD0580  [5]
 LDCM0264  AC144 HCT 116 C452(1.09); C171(1.59)  LDD0581  [5]
 LDCM0265  AC145 HCT 116 C452(0.94); C171(1.62)  LDD0582  [5]
 LDCM0266  AC146 HCT 116 C171(1.07); C452(1.24)  LDD0583  [5]
 LDCM0267  AC147 HCT 116 C452(1.26); C171(1.26)  LDD0584  [5]
 LDCM0268  AC148 HCT 116 C452(1.11); C171(1.91)  LDD0585  [5]
 LDCM0269  AC149 HCT 116 C452(1.10); C171(2.36)  LDD0586  [5]
 LDCM0270  AC15 HCT 116 C452(1.89)  LDD0587  [5]
 LDCM0271  AC150 HCT 116 C452(1.47); C171(1.61)  LDD0588  [5]
 LDCM0272  AC151 HCT 116 C171(0.90); C452(1.28)  LDD0589  [5]
 LDCM0273  AC152 HCT 116 C171(1.13); C452(1.21)  LDD0590  [5]
 LDCM0274  AC153 HCT 116 C452(1.31); C171(3.75)  LDD0591  [5]
 LDCM0621  AC154 HCT 116 C171(1.04); C452(1.39)  LDD2158  [5]
 LDCM0622  AC155 HCT 116 C171(1.58); C452(1.52)  LDD2159  [5]
 LDCM0623  AC156 HCT 116 C171(1.45); C452(1.15)  LDD2160  [5]
 LDCM0624  AC157 HCT 116 C171(1.29); C452(1.79)  LDD2161  [5]
 LDCM0276  AC17 HCT 116 C452(0.76)  LDD0593  [5]
 LDCM0277  AC18 HCT 116 C452(0.94)  LDD0594  [5]
 LDCM0278  AC19 HCT 116 C452(0.92)  LDD0595  [5]
 LDCM0279  AC2 HCT 116 C171(0.95); C452(1.19)  LDD0596  [5]
 LDCM0280  AC20 HCT 116 C452(0.62)  LDD0597  [5]
 LDCM0281  AC21 HCT 116 C452(0.65)  LDD0598  [5]
 LDCM0282  AC22 HCT 116 C452(0.27)  LDD0599  [5]
 LDCM0283  AC23 HCT 116 C452(0.63)  LDD0600  [5]
 LDCM0284  AC24 HCT 116 C452(0.52)  LDD0601  [5]
 LDCM0285  AC25 HEK-293T C452(0.97)  LDD0883  [5]
 LDCM0286  AC26 HEK-293T C452(1.12)  LDD0884  [5]
 LDCM0287  AC27 HEK-293T C452(1.04)  LDD0885  [5]
 LDCM0288  AC28 HEK-293T C452(0.87)  LDD0886  [5]
 LDCM0289  AC29 HEK-293T C452(0.98)  LDD0887  [5]
 LDCM0290  AC3 HCT 116 C171(0.91); C452(1.10)  LDD0607  [5]
 LDCM0291  AC30 HEK-293T C452(1.08)  LDD0889  [5]
 LDCM0292  AC31 HEK-293T C452(0.92)  LDD0890  [5]
 LDCM0293  AC32 HEK-293T C452(1.08)  LDD0891  [5]
 LDCM0294  AC33 HEK-293T C452(0.92)  LDD0892  [5]
 LDCM0295  AC34 HEK-293T C452(1.02)  LDD0893  [5]
 LDCM0296  AC35 HCT 116 C171(1.19)  LDD0613  [5]
 LDCM0297  AC36 HCT 116 C171(1.23)  LDD0614  [5]
 LDCM0298  AC37 HCT 116 C171(1.47)  LDD0615  [5]
 LDCM0299  AC38 HCT 116 C171(1.70)  LDD0616  [5]
 LDCM0300  AC39 HCT 116 C171(2.25)  LDD0617  [5]
 LDCM0301  AC4 HCT 116 C171(0.86); C452(1.07)  LDD0618  [5]
 LDCM0302  AC40 HCT 116 C171(1.82)  LDD0619  [5]
 LDCM0303  AC41 HCT 116 C171(2.07)  LDD0620  [5]
 LDCM0304  AC42 HCT 116 C171(1.40)  LDD0621  [5]
 LDCM0305  AC43 HCT 116 C171(1.44)  LDD0622  [5]
 LDCM0306  AC44 HCT 116 C171(2.18)  LDD0623  [5]
 LDCM0307  AC45 HCT 116 C171(1.97)  LDD0624  [5]
 LDCM0308  AC46 HCT 116 C636(1.06); C639(1.06)  LDD0625  [5]
 LDCM0309  AC47 HCT 116 C636(0.82); C639(0.82)  LDD0626  [5]
 LDCM0310  AC48 HCT 116 C636(1.74); C639(1.74)  LDD0627  [5]
 LDCM0311  AC49 HCT 116 C636(0.81); C639(0.81)  LDD0628  [5]
 LDCM0312  AC5 HCT 116 C171(0.92); C452(1.21)  LDD0629  [5]
 LDCM0313  AC50 HCT 116 C636(0.81); C639(0.81)  LDD0630  [5]
 LDCM0314  AC51 HCT 116 C636(1.83); C639(1.83)  LDD0631  [5]
 LDCM0315  AC52 HCT 116 C636(0.97); C639(0.97)  LDD0632  [5]
 LDCM0316  AC53 HCT 116 C636(0.95); C639(0.95)  LDD0633  [5]
 LDCM0317  AC54 HCT 116 C636(0.80); C639(0.80)  LDD0634  [5]
 LDCM0318  AC55 HCT 116 C636(0.81); C639(0.81)  LDD0635  [5]
 LDCM0319  AC56 HCT 116 C636(0.83); C639(0.83)  LDD0636  [5]
 LDCM0320  AC57 HEK-293T C244(1.00)  LDD0918  [5]
 LDCM0321  AC58 HEK-293T C244(1.20)  LDD0919  [5]
 LDCM0322  AC59 HEK-293T C244(1.17)  LDD0920  [5]
 LDCM0323  AC6 HCT 116 C452(1.82)  LDD0640  [5]
 LDCM0324  AC60 HEK-293T C244(0.84)  LDD0922  [5]
 LDCM0325  AC61 HEK-293T C244(1.07)  LDD0923  [5]
 LDCM0326  AC62 HEK-293T C244(0.95)  LDD0924  [5]
 LDCM0327  AC63 HEK-293T C244(1.16)  LDD0925  [5]
 LDCM0328  AC64 HEK-293T C244(1.08)  LDD0926  [5]
 LDCM0329  AC65 HEK-293T C244(1.02)  LDD0927  [5]
 LDCM0330  AC66 HEK-293T C244(1.01)  LDD0928  [5]
 LDCM0331  AC67 HEK-293T C244(1.14)  LDD0929  [5]
 LDCM0332  AC68 HCT 116 C636(0.82); C639(0.82); C452(0.89); C171(0.99)  LDD0649  [5]
 LDCM0333  AC69 HCT 116 C452(0.71); C636(0.83); C639(0.83); C171(1.05)  LDD0650  [5]
 LDCM0334  AC7 HCT 116 C452(1.69)  LDD0651  [5]
 LDCM0335  AC70 HCT 116 C636(0.71); C639(0.71); C452(0.86); C171(1.07)  LDD0652  [5]
 LDCM0336  AC71 HCT 116 C452(0.86); C171(0.88); C636(1.02); C639(1.02)  LDD0653  [5]
 LDCM0337  AC72 HCT 116 C636(0.77); C639(0.77); C452(1.01); C171(1.10)  LDD0654  [5]
 LDCM0338  AC73 HCT 116 C636(0.67); C639(0.67); C452(1.13); C171(1.59)  LDD0655  [5]
 LDCM0339  AC74 HCT 116 C636(0.65); C639(0.65); C452(1.19); C171(1.27)  LDD0656  [5]
 LDCM0340  AC75 HCT 116 C636(0.72); C639(0.72); C452(1.03); C171(1.54)  LDD0657  [5]
 LDCM0341  AC76 HCT 116 C636(0.77); C639(0.77); C452(0.87); C171(1.23)  LDD0658  [5]
 LDCM0342  AC77 HCT 116 C636(0.94); C639(0.94); C452(1.02); C171(1.46)  LDD0659  [5]
 LDCM0343  AC78 HCT 116 C452(0.90); C636(1.04); C639(1.04); C171(1.12)  LDD0660  [5]
 LDCM0344  AC79 HCT 116 C636(0.85); C639(0.85); C452(0.89); C171(0.94)  LDD0661  [5]
 LDCM0345  AC8 HCT 116 C452(1.57)  LDD0662  [5]
 LDCM0346  AC80 HCT 116 C636(0.70); C639(0.70); C452(0.93); C171(1.11)  LDD0663  [5]
 LDCM0347  AC81 HCT 116 C171(0.90); C636(0.95); C639(0.95); C452(0.99)  LDD0664  [5]
 LDCM0348  AC82 HCT 116 C636(0.72); C639(0.72); C452(0.91); C171(1.53)  LDD0665  [5]
 LDCM0349  AC83 HCT 116 C452(1.30); C171(1.63)  LDD0666  [5]
 LDCM0350  AC84 HCT 116 C452(1.41); C171(1.50)  LDD0667  [5]
 LDCM0351  AC85 HCT 116 C452(0.96); C171(1.27)  LDD0668  [5]
 LDCM0352  AC86 HCT 116 C452(1.09); C171(1.34)  LDD0669  [5]
 LDCM0353  AC87 HCT 116 C171(1.07); C452(1.15)  LDD0670  [5]
 LDCM0354  AC88 HCT 116 C452(0.90); C171(1.23)  LDD0671  [5]
 LDCM0355  AC89 HCT 116 C452(0.84); C171(1.38)  LDD0672  [5]
 LDCM0357  AC90 HCT 116 C452(0.66); C171(1.24)  LDD0674  [5]
 LDCM0358  AC91 HCT 116 C452(1.22); C171(1.70)  LDD0675  [5]
 LDCM0359  AC92 HCT 116 C452(1.09); C171(1.64)  LDD0676  [5]
 LDCM0360  AC93 HCT 116 C171(1.39); C452(1.53)  LDD0677  [5]
 LDCM0361  AC94 HCT 116 C452(1.02); C171(1.39)  LDD0678  [5]
 LDCM0362  AC95 HCT 116 C452(0.94); C171(1.31)  LDD0679  [5]
 LDCM0363  AC96 HCT 116 C452(0.90); C171(1.38)  LDD0680  [5]
 LDCM0364  AC97 HCT 116 C452(0.89); C171(1.55)  LDD0681  [5]
 LDCM0365  AC98 HCT 116 C452(1.26)  LDD0682  [5]
 LDCM0366  AC99 HCT 116 C452(1.15)  LDD0683  [5]
 LDCM0248  AKOS034007472 HCT 116 C452(1.27)  LDD0565  [5]
 LDCM0356  AKOS034007680 HCT 116 C452(1.79)  LDD0673  [5]
 LDCM0275  AKOS034007705 HCT 116 C452(3.21)  LDD0592  [5]
 LDCM0020  ARS-1620 HCC44 C171(1.30)  LDD2171  [5]
 LDCM0367  CL1 HCT 116 C171(1.05); C452(1.12)  LDD0684  [5]
 LDCM0368  CL10 HCT 116 C452(0.66); C171(0.98)  LDD0685  [5]
 LDCM0369  CL100 HCT 116 C171(0.97); C452(1.20)  LDD0686  [5]
 LDCM0370  CL101 HCT 116 C452(1.62)  LDD0687  [5]
 LDCM0371  CL102 HCT 116 C452(1.29)  LDD0688  [5]
 LDCM0372  CL103 HCT 116 C452(1.38)  LDD0689  [5]
 LDCM0373  CL104 HCT 116 C452(2.62)  LDD0690  [5]
 LDCM0374  CL105 HCT 116 C452(0.80)  LDD0691  [5]
 LDCM0375  CL106 HCT 116 C452(0.92)  LDD0692  [5]
 LDCM0376  CL107 HCT 116 C452(1.07)  LDD0693  [5]
 LDCM0377  CL108 HCT 116 C452(0.81)  LDD0694  [5]
 LDCM0378  CL109 HCT 116 C452(1.04)  LDD0695  [5]
 LDCM0379  CL11 HCT 116 C452(1.01); C171(1.24)  LDD0696  [5]
 LDCM0380  CL110 HCT 116 C452(0.90)  LDD0697  [5]
 LDCM0381  CL111 HCT 116 C452(0.90)  LDD0698  [5]
 LDCM0382  CL112 HEK-293T C452(1.07)  LDD0980  [5]
 LDCM0383  CL113 HEK-293T C452(1.20)  LDD0981  [5]
 LDCM0384  CL114 HEK-293T C452(1.48)  LDD0982  [5]
 LDCM0385  CL115 HEK-293T C452(1.09)  LDD0983  [5]
 LDCM0386  CL116 HEK-293T C452(1.17)  LDD0984  [5]
 LDCM0387  CL117 HCT 116 C171(1.50)  LDD0704  [5]
 LDCM0388  CL118 HCT 116 C171(1.35)  LDD0705  [5]
 LDCM0389  CL119 HCT 116 C171(1.33)  LDD0706  [5]
 LDCM0390  CL12 HCT 116 C452(0.95); C171(1.12)  LDD0707  [5]
 LDCM0391  CL120 HCT 116 C171(1.21)  LDD0708  [5]
 LDCM0392  CL121 HCT 116 C636(2.16); C639(2.16)  LDD0709  [5]
 LDCM0393  CL122 HCT 116 C636(1.09); C639(1.09)  LDD0710  [5]
 LDCM0394  CL123 HCT 116 C636(0.77); C639(0.77)  LDD0711  [5]
 LDCM0395  CL124 HCT 116 C636(0.72); C639(0.72)  LDD0712  [5]
 LDCM0396  CL125 HEK-293T C244(0.88)  LDD0994  [5]
 LDCM0397  CL126 HEK-293T C244(1.04)  LDD0995  [5]
 LDCM0398  CL127 HEK-293T C244(0.88)  LDD0996  [5]
 LDCM0399  CL128 HEK-293T C244(1.00)  LDD0997  [5]
 LDCM0400  CL13 HCT 116 C452(1.06); C171(1.06)  LDD0717  [5]
 LDCM0401  CL14 HCT 116 C452(1.00); C171(1.21)  LDD0718  [5]
 LDCM0402  CL15 HCT 116 C452(0.95); C171(1.05)  LDD0719  [5]
 LDCM0403  CL16 HCT 116 C171(0.91); C636(1.09); C639(1.09)  LDD0720  [5]
 LDCM0404  CL17 HCT 116 C636(0.82); C639(0.82); C452(0.84); C171(1.01)  LDD0721  [5]
 LDCM0405  CL18 HCT 116 C452(0.83); C171(1.04); C636(1.22); C639(1.22)  LDD0722  [5]
 LDCM0406  CL19 HCT 116 C171(1.09); C452(1.18); C636(1.23); C639(1.23)  LDD0723  [5]
 LDCM0407  CL2 HCT 116 C452(0.68); C171(1.18)  LDD0724  [5]
 LDCM0408  CL20 HCT 116 C171(1.02); C636(1.13); C639(1.13); C452(1.20)  LDD0725  [5]
 LDCM0409  CL21 HCT 116 C636(0.74); C639(0.74); C452(0.82); C171(0.84)  LDD0726  [5]
 LDCM0410  CL22 HCT 116 C452(0.61); C636(0.86); C639(0.86); C171(0.94)  LDD0727  [5]
 LDCM0411  CL23 HCT 116 C452(0.75); C636(0.82); C639(0.82); C171(1.14)  LDD0728  [5]
 LDCM0412  CL24 HCT 116 C171(1.02); C452(0.85); C636(1.14); C639(1.14)  LDD0729  [5]
 LDCM0413  CL25 HCT 116 C171(1.02); C452(0.82); C636(0.89); C639(0.89)  LDD0730  [5]
 LDCM0414  CL26 HCT 116 C171(1.12); C452(0.74); C636(0.80); C639(0.80)  LDD0731  [5]
 LDCM0415  CL27 HCT 116 C171(1.21); C452(0.80); C636(1.19); C639(1.19)  LDD0732  [5]
 LDCM0416  CL28 HCT 116 C171(1.20); C452(0.82); C636(0.94); C639(0.94)  LDD0733  [5]
 LDCM0417  CL29 HCT 116 C171(1.09); C452(0.84); C636(1.28); C639(1.28)  LDD0734  [5]
 LDCM0418  CL3 HCT 116 C171(1.06); C452(0.83)  LDD0735  [5]
 LDCM0419  CL30 HCT 116 C171(1.03); C452(0.89); C636(1.29); C639(1.29)  LDD0736  [5]
 LDCM0420  CL31 HCT 116 C171(0.92); C452(0.82)  LDD0737  [5]
 LDCM0421  CL32 HEK-293T C452(0.87)  LDD1019  [5]
 LDCM0422  CL33 HEK-293T C452(2.57)  LDD1020  [5]
 LDCM0423  CL34 HEK-293T C452(1.50)  LDD1021  [5]
 LDCM0424  CL35 HEK-293T C452(1.14)  LDD1022  [5]
 LDCM0425  CL36 HEK-293T C452(1.14)  LDD1023  [5]
 LDCM0426  CL37 HEK-293T C452(1.99)  LDD1024  [5]
 LDCM0428  CL39 HEK-293T C452(2.57)  LDD1026  [5]
 LDCM0429  CL4 HCT 116 C171(1.10); C452(1.00)  LDD0746  [5]
 LDCM0430  CL40 HEK-293T C452(0.91)  LDD1028  [5]
 LDCM0431  CL41 HEK-293T C452(1.59)  LDD1029  [5]
 LDCM0432  CL42 HEK-293T C452(1.48)  LDD1030  [5]
 LDCM0433  CL43 HEK-293T C452(1.59)  LDD1031  [5]
 LDCM0434  CL44 HEK-293T C452(1.27)  LDD1032  [5]
 LDCM0435  CL45 HEK-293T C452(2.78)  LDD1033  [5]
 LDCM0436  CL46 HEK-293T C452(0.99); C262(0.80)  LDD1640  [6]
 LDCM0437  CL47 HEK-293T C452(1.08); C639(1.16)  LDD1641  [6]
 LDCM0438  CL48 HEK-293T C452(1.07); C262(1.18)  LDD1642  [6]
 LDCM0439  CL49 HEK-293T C452(0.91)  LDD1643  [6]
 LDCM0440  CL5 HCT 116 C171(1.04); C452(0.87)  LDD0757  [5]
 LDCM0441  CL50 HEK-293T C452(1.05)  LDD1645  [6]
 LDCM0443  CL52 HEK-293T C452(1.05)  LDD1646  [6]
 LDCM0444  CL53 HEK-293T C262(0.83)  LDD1647  [6]
 LDCM0445  CL54 HEK-293T C452(1.07)  LDD1648  [6]
 LDCM0446  CL55 HEK-293T C452(1.08); C152(0.73); C262(1.16)  LDD1649  [6]
 LDCM0447  CL56 HEK-293T C452(1.32)  LDD1650  [6]
 LDCM0448  CL57 HEK-293T C452(1.16); C262(1.15)  LDD1651  [6]
 LDCM0449  CL58 HEK-293T C452(1.09); C262(0.81)  LDD1652  [6]
 LDCM0450  CL59 HEK-293T C452(1.00); C639(1.09)  LDD1653  [6]
 LDCM0451  CL6 HCT 116 C171(1.15); C452(0.99)  LDD0768  [5]
 LDCM0452  CL60 HEK-293T C452(1.08); C262(0.94)  LDD1655  [6]
 LDCM0453  CL61 HCT 116 C171(1.16)  LDD0770  [5]
 LDCM0454  CL62 HCT 116 C171(1.05)  LDD0771  [5]
 LDCM0455  CL63 HCT 116 C171(1.17)  LDD0772  [5]
 LDCM0456  CL64 HCT 116 C171(1.29)  LDD0773  [5]
 LDCM0457  CL65 HCT 116 C171(1.07)  LDD0774  [5]
 LDCM0458  CL66 HCT 116 C171(1.61)  LDD0775  [5]
 LDCM0459  CL67 HCT 116 C171(0.97)  LDD0776  [5]
 LDCM0460  CL68 HCT 116 C171(1.24)  LDD0777  [5]
 LDCM0461  CL69 HCT 116 C171(0.80)  LDD0778  [5]
 LDCM0462  CL7 HCT 116 C171(1.19); C452(1.26)  LDD0779  [5]
 LDCM0463  CL70 HCT 116 C171(1.11)  LDD0780  [5]
 LDCM0464  CL71 HCT 116 C171(1.33)  LDD0781  [5]
 LDCM0465  CL72 HCT 116 C171(1.10)  LDD0782  [5]
 LDCM0466  CL73 HCT 116 C171(1.07)  LDD0783  [5]
 LDCM0467  CL74 HCT 116 C171(1.24)  LDD0784  [5]
 LDCM0469  CL76 HEK-293T C244(1.04)  LDD1067  [5]
 LDCM0470  CL77 HEK-293T C244(1.21)  LDD1068  [5]
 LDCM0471  CL78 HEK-293T C244(1.02)  LDD1069  [5]
 LDCM0472  CL79 HEK-293T C244(1.06)  LDD1070  [5]
 LDCM0473  CL8 HCT 116 C171(1.44); C452(0.82)  LDD0790  [5]
 LDCM0474  CL80 HEK-293T C244(1.18)  LDD1072  [5]
 LDCM0475  CL81 HEK-293T C244(0.95)  LDD1073  [5]
 LDCM0476  CL82 HEK-293T C244(1.20)  LDD1074  [5]
 LDCM0477  CL83 HEK-293T C244(1.32)  LDD1075  [5]
 LDCM0478  CL84 HEK-293T C244(1.20)  LDD1076  [5]
 LDCM0479  CL85 HEK-293T C244(1.09)  LDD1077  [5]
 LDCM0480  CL86 HEK-293T C244(0.92)  LDD1078  [5]
 LDCM0481  CL87 HEK-293T C244(1.32)  LDD1079  [5]
 LDCM0482  CL88 HEK-293T C244(1.04)  LDD1080  [5]
 LDCM0483  CL89 HEK-293T C244(1.45)  LDD1081  [5]
 LDCM0484  CL9 HCT 116 C171(1.14); C452(0.91)  LDD0801  [5]
 LDCM0485  CL90 HEK-293T C244(3.41)  LDD1083  [5]
 LDCM0486  CL91 HCT 116 C171(1.10); C452(1.42)  LDD0803  [5]
 LDCM0487  CL92 HCT 116 C171(0.81); C452(1.41)  LDD0804  [5]
 LDCM0488  CL93 HCT 116 C171(0.85); C452(0.94)  LDD0805  [5]
 LDCM0489  CL94 HCT 116 C171(0.86); C452(1.24)  LDD0806  [5]
 LDCM0490  CL95 HCT 116 C171(0.93); C452(1.39)  LDD0807  [5]
 LDCM0491  CL96 HCT 116 C171(0.86); C452(1.32)  LDD0808  [5]
 LDCM0492  CL97 HCT 116 C171(0.91); C452(1.01)  LDD0809  [5]
 LDCM0493  CL98 HCT 116 C171(0.91); C452(1.14)  LDD0810  [5]
 LDCM0494  CL99 HCT 116 C171(0.94); C452(0.96)  LDD0811  [5]
 LDCM0495  E2913 HEK-293T C452(0.99); C262(0.78)  LDD1698  [6]
 LDCM0468  Fragment33 HCT 116 C171(1.12)  LDD0785  [5]
 LDCM0427  Fragment51 HEK-293T C452(1.38)  LDD1025  [5]
 LDCM0022  KB02 HEK-293T C152(0.94); C262(0.92)  LDD1492  [6]
 LDCM0023  KB03 Jurkat C452(40.16)  LDD0209  [1]
 LDCM0024  KB05 COLO792 C182(3.16); C273(1.76)  LDD3310  [7]
 LDCM0021  THZ1 HCT 116 C171(1.30)  LDD2173  [5]

References

1 Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.
2 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
3 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
4 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010
5 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
6 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
7 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840