Details of the Target

General Information of Target

Target ID LDTP11082
Target Name Allograft inflammatory factor 1-like (AIF1L)
Gene Name AIF1L
Gene ID 83543
Synonyms
C9orf58; IBA2; Allograft inflammatory factor 1-like; Ionized calcium-binding adapter molecule 2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSSVKRSLKQEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPE
IVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATAKGGKKPWFLTNEVEECENY
FSKTLLDRKSEKRNNSDWLLAKESHPATVFILFSDLNPLVTLGGNKESFQQPEVRLCQLN
YTDIKDYLAQPEKITLIFLGVELEIKDKLLNYAGEVPREEEDGLVAWFALGIDPIAAEEF
KQRHENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWHSRYKFCPTCGNATKIEEGGYKR
LCLKEDCPSLNGVHNTSYPRVDPVVIMQVIHPDGTKCLLGRQKRFPPGMFTCLAGFIEPG
ETIEDAVRREVEEESGVKVGHVQYVACQPWPMPSSLMIGCLALAVSTEIKVDKNEIEDAR
WFTREQVLDVLTKGKQQAFFVPPSRAIAHQLIKHWIRINPNL
Target Bioclass
Other
Subcellular location
Cytoplasm, cytoskeleton
Function Actin-binding protein that promotes actin bundling. May neither bind calcium nor depend on calcium for function.
Uniprot ID
Q9BQI0
Ensemble ID
ENST00000247291.8
HGNC ID
HGNC:28904

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CAL72 SNV: p.K90N .
Ishikawa (Heraklio) 02 ER Deletion: p.K136SfsTer38 .
NCIH358 SNV: p.E87Q DBIA    Probe Info 
OPM2 SNV: p.K121M .
SKN SNV: p.E23Q .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
AHL-Pu-1
 Probe Info  		C35(2.40)  LDD0169  [1]
DBIA
 Probe Info  		C35(1.18)  LDD0531  [2]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [3]
NAIA_5
 Probe Info  		N.A.  LDD2223  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0026  4SU-RNA+native RNA HEK-293T C35(2.40)  LDD0169  [1]
 LDCM0214  AC1 HCT 116 C35(1.18)  LDD0531  [2]
 LDCM0215  AC10 HEK-293T C35(0.89)  LDD1508  [5]
 LDCM0216  AC100 HCT 116 C35(1.02)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C35(1.11)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C35(1.15)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C35(1.30)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C35(1.04)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C35(1.17)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C35(1.35)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C35(1.27)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C35(1.09)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C35(0.89)  LDD0542  [2]
 LDCM0226  AC11 HEK-293T C35(0.95)  LDD1509  [5]
 LDCM0227  AC110 HCT 116 C35(1.01)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C35(0.93)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C35(1.27)  LDD0546  [2]
 LDCM0237  AC12 HEK-293T C35(0.96)  LDD1510  [5]
 LDCM0246  AC128 HEK-293T C35(0.95)  LDD0844  [2]
 LDCM0247  AC129 HEK-293T C35(1.15)  LDD0845  [2]
 LDCM0249  AC130 HEK-293T C35(1.24)  LDD0847  [2]
 LDCM0250  AC131 HEK-293T C35(1.46)  LDD0848  [2]
 LDCM0251  AC132 HEK-293T C35(1.47)  LDD0849  [2]
 LDCM0252  AC133 HEK-293T C35(1.37)  LDD0850  [2]
 LDCM0253  AC134 HEK-293T C35(1.55)  LDD0851  [2]
 LDCM0254  AC135 HEK-293T C35(1.64)  LDD0852  [2]
 LDCM0255  AC136 HEK-293T C35(1.63)  LDD0853  [2]
 LDCM0256  AC137 HEK-293T C35(1.80)  LDD0854  [2]
 LDCM0257  AC138 HEK-293T C35(2.17)  LDD0855  [2]
 LDCM0258  AC139 HEK-293T C35(2.02)  LDD0856  [2]
 LDCM0259  AC14 HEK-293T C35(0.94)  LDD1512  [5]
 LDCM0260  AC140 HEK-293T C35(1.82)  LDD0858  [2]
 LDCM0261  AC141 HEK-293T C35(2.23)  LDD0859  [2]
 LDCM0262  AC142 HEK-293T C35(1.60)  LDD0860  [2]
 LDCM0263  AC143 HCT 116 C35(1.13)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C35(1.30)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C35(1.51)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C35(1.46)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C35(1.63)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C35(2.00)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C35(1.59)  LDD0586  [2]
 LDCM0270  AC15 HEK-293T C35(0.99)  LDD1513  [5]
 LDCM0271  AC150 HCT 116 C35(1.16)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C35(1.41)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C35(1.78)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C35(1.63)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C35(1.65)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C35(1.29)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C35(1.19)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C35(0.85)  LDD2161  [2]
 LDCM0276  AC17 HCT 116 C35(1.09)  LDD0593  [2]
 LDCM0277  AC18 HCT 116 C35(1.18)  LDD0594  [2]
 LDCM0278  AC19 HCT 116 C35(1.06)  LDD0595  [2]
 LDCM0279  AC2 HCT 116 C35(1.02)  LDD0596  [2]
 LDCM0280  AC20 HCT 116 C35(0.91)  LDD0597  [2]
 LDCM0281  AC21 HCT 116 C35(0.90)  LDD0598  [2]
 LDCM0282  AC22 HCT 116 C35(1.10)  LDD0599  [2]
 LDCM0283  AC23 HCT 116 C35(0.99)  LDD0600  [2]
 LDCM0284  AC24 HCT 116 C35(1.01)  LDD0601  [2]
 LDCM0285  AC25 HEK-293T C35(1.16)  LDD0883  [2]
 LDCM0286  AC26 HEK-293T C35(1.32)  LDD0884  [2]
 LDCM0287  AC27 HEK-293T C35(1.55)  LDD0885  [2]
 LDCM0288  AC28 HEK-293T C35(1.15)  LDD0886  [2]
 LDCM0289  AC29 HEK-293T C35(1.23)  LDD0887  [2]
 LDCM0290  AC3 HCT 116 C35(1.11)  LDD0607  [2]
 LDCM0291  AC30 HEK-293T C35(1.47)  LDD0889  [2]
 LDCM0292  AC31 HEK-293T C35(1.15)  LDD0890  [2]
 LDCM0293  AC32 HEK-293T C35(1.28)  LDD0891  [2]
 LDCM0294  AC33 HEK-293T C35(1.35)  LDD0892  [2]
 LDCM0295  AC34 HEK-293T C35(1.32)  LDD0893  [2]
 LDCM0296  AC35 HCT 116 C35(0.95)  LDD0613  [2]
 LDCM0297  AC36 HCT 116 C35(0.87)  LDD0614  [2]
 LDCM0298  AC37 HCT 116 C35(1.08)  LDD0615  [2]
 LDCM0299  AC38 HCT 116 C35(1.18)  LDD0616  [2]
 LDCM0300  AC39 HCT 116 C35(0.89)  LDD0617  [2]
 LDCM0301  AC4 HCT 116 C35(1.04)  LDD0618  [2]
 LDCM0302  AC40 HCT 116 C35(0.88)  LDD0619  [2]
 LDCM0303  AC41 HCT 116 C35(1.01)  LDD0620  [2]
 LDCM0304  AC42 HCT 116 C35(0.88)  LDD0621  [2]
 LDCM0305  AC43 HCT 116 C35(1.07)  LDD0622  [2]
 LDCM0306  AC44 HCT 116 C35(0.92)  LDD0623  [2]
 LDCM0307  AC45 HCT 116 C35(0.74)  LDD0624  [2]
 LDCM0308  AC46 HCT 116 C35(1.51)  LDD0625  [2]
 LDCM0309  AC47 HCT 116 C35(1.24)  LDD0626  [2]
 LDCM0310  AC48 HCT 116 C35(0.94)  LDD0627  [2]
 LDCM0311  AC49 HCT 116 C35(1.49)  LDD0628  [2]
 LDCM0312  AC5 HCT 116 C35(1.16)  LDD0629  [2]
 LDCM0313  AC50 HCT 116 C35(1.80)  LDD0630  [2]
 LDCM0314  AC51 HCT 116 C35(1.13)  LDD0631  [2]
 LDCM0315  AC52 HCT 116 C35(1.07)  LDD0632  [2]
 LDCM0316  AC53 HCT 116 C35(1.21)  LDD0633  [2]
 LDCM0317  AC54 HCT 116 C35(1.36)  LDD0634  [2]
 LDCM0318  AC55 HCT 116 C35(0.96)  LDD0635  [2]
 LDCM0319  AC56 HCT 116 C35(1.10)  LDD0636  [2]
 LDCM0320  AC57 HCT 116 C35(1.28)  LDD0637  [2]
 LDCM0321  AC58 HCT 116 C35(1.20)  LDD0638  [2]
 LDCM0322  AC59 HCT 116 C35(1.82)  LDD0639  [2]
 LDCM0323  AC6 HEK-293T C35(0.82)  LDD1562  [5]
 LDCM0324  AC60 HCT 116 C35(1.46)  LDD0641  [2]
 LDCM0325  AC61 HCT 116 C35(1.26)  LDD0642  [2]
 LDCM0326  AC62 HCT 116 C35(1.44)  LDD0643  [2]
 LDCM0327  AC63 HCT 116 C35(1.37)  LDD0644  [2]
 LDCM0328  AC64 HCT 116 C35(1.48)  LDD0645  [2]
 LDCM0329  AC65 HCT 116 C35(1.83)  LDD0646  [2]
 LDCM0330  AC66 HCT 116 C35(1.83)  LDD0647  [2]
 LDCM0331  AC67 HCT 116 C35(2.03)  LDD0648  [2]
 LDCM0332  AC68 HCT 116 C35(0.94)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C35(0.79)  LDD0650  [2]
 LDCM0334  AC7 HEK-293T C35(0.95)  LDD1568  [5]
 LDCM0335  AC70 HCT 116 C35(0.79)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C35(0.88)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C35(0.91)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C35(0.94)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C35(0.97)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C35(0.82)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C35(0.88)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C35(0.79)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C35(0.83)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C35(0.79)  LDD0661  [2]
 LDCM0345  AC8 HEK-293T C35(0.92)  LDD1569  [5]
 LDCM0346  AC80 HCT 116 C35(0.83)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C35(0.81)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C35(0.87)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C35(1.22)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C35(0.97)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C35(1.12)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C35(1.25)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C35(1.07)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C35(1.01)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C35(0.88)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C35(1.01)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C35(0.90)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C35(0.99)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C35(0.88)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C35(1.48)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C35(0.83)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C35(1.32)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C35(1.02)  LDD0681  [2]
 LDCM0365  AC98 HCT 116 C35(1.29)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C35(0.89)  LDD0683  [2]
 LDCM0248  AKOS034007472 HEK-293T C35(0.98)  LDD1511  [5]
 LDCM0356  AKOS034007680 HEK-293T C35(0.92)  LDD1570  [5]
 LDCM0275  AKOS034007705 HEK-293T C35(0.88)  LDD1514  [5]
 LDCM0367  CL1 HCT 116 C35(0.72)  LDD0684  [2]
 LDCM0368  CL10 HCT 116 C35(1.19)  LDD0685  [2]
 LDCM0369  CL100 HCT 116 C35(1.14)  LDD0686  [2]
 LDCM0370  CL101 HEK-293T C35(0.94)  LDD1574  [5]
 LDCM0371  CL102 HEK-293T C35(0.86)  LDD1575  [5]
 LDCM0372  CL103 HEK-293T C35(0.89)  LDD1576  [5]
 LDCM0373  CL104 HEK-293T C35(0.89)  LDD1577  [5]
 LDCM0374  CL105 HCT 116 C35(1.27)  LDD0691  [2]
 LDCM0375  CL106 HCT 116 C35(1.40)  LDD0692  [2]
 LDCM0376  CL107 HCT 116 C35(1.06)  LDD0693  [2]
 LDCM0377  CL108 HCT 116 C35(1.43)  LDD0694  [2]
 LDCM0378  CL109 HCT 116 C35(1.22)  LDD0695  [2]
 LDCM0379  CL11 HCT 116 C35(1.40)  LDD0696  [2]
 LDCM0380  CL110 HCT 116 C35(1.17)  LDD0697  [2]
 LDCM0381  CL111 HCT 116 C35(1.16)  LDD0698  [2]
 LDCM0382  CL112 HEK-293T C35(1.28)  LDD0980  [2]
 LDCM0383  CL113 HEK-293T C35(1.36)  LDD0981  [2]
 LDCM0384  CL114 HEK-293T C35(1.43)  LDD0982  [2]
 LDCM0385  CL115 HEK-293T C35(1.53)  LDD0983  [2]
 LDCM0386  CL116 HEK-293T C35(1.51)  LDD0984  [2]
 LDCM0387  CL117 HCT 116 C35(0.76)  LDD0704  [2]
 LDCM0388  CL118 HCT 116 C35(0.96)  LDD0705  [2]
 LDCM0389  CL119 HCT 116 C35(0.91)  LDD0706  [2]
 LDCM0390  CL12 HCT 116 C35(1.50)  LDD0707  [2]
 LDCM0391  CL120 HCT 116 C35(0.83)  LDD0708  [2]
 LDCM0392  CL121 HCT 116 C35(1.21)  LDD0709  [2]
 LDCM0393  CL122 HCT 116 C35(1.13)  LDD0710  [2]
 LDCM0394  CL123 HCT 116 C35(0.92)  LDD0711  [2]
 LDCM0395  CL124 HCT 116 C35(1.19)  LDD0712  [2]
 LDCM0396  CL125 HCT 116 C35(1.14)  LDD0713  [2]
 LDCM0397  CL126 HCT 116 C35(1.06)  LDD0714  [2]
 LDCM0398  CL127 HCT 116 C35(1.13)  LDD0715  [2]
 LDCM0399  CL128 HCT 116 C35(1.45)  LDD0716  [2]
 LDCM0400  CL13 HCT 116 C35(1.26)  LDD0717  [2]
 LDCM0401  CL14 HCT 116 C35(0.91)  LDD0718  [2]
 LDCM0402  CL15 HCT 116 C35(1.08)  LDD0719  [2]
 LDCM0403  CL16 HEK-293T C35(0.77)  LDD1001  [2]
 LDCM0404  CL17 HEK-293T C35(0.88)  LDD1002  [2]
 LDCM0405  CL18 HEK-293T C35(1.38)  LDD1003  [2]
 LDCM0406  CL19 HEK-293T C35(1.06)  LDD1004  [2]
 LDCM0407  CL2 HCT 116 C35(0.89)  LDD0724  [2]
 LDCM0408  CL20 HEK-293T C35(1.29)  LDD1006  [2]
 LDCM0409  CL21 HEK-293T C35(1.08)  LDD1007  [2]
 LDCM0410  CL22 HEK-293T C35(1.30)  LDD1008  [2]
 LDCM0411  CL23 HEK-293T C35(1.09)  LDD1009  [2]
 LDCM0412  CL24 HEK-293T C35(0.97)  LDD1010  [2]
 LDCM0413  CL25 HEK-293T C35(1.24)  LDD1011  [2]
 LDCM0414  CL26 HEK-293T C35(1.09)  LDD1012  [2]
 LDCM0415  CL27 HEK-293T C35(1.23)  LDD1013  [2]
 LDCM0416  CL28 HEK-293T C35(1.04)  LDD1014  [2]
 LDCM0417  CL29 HEK-293T C35(1.04)  LDD1015  [2]
 LDCM0418  CL3 HCT 116 C35(0.88)  LDD0735  [2]
 LDCM0419  CL30 HEK-293T C35(1.45)  LDD1017  [2]
 LDCM0420  CL31 HEK-293T C35(0.94)  LDD1624  [5]
 LDCM0421  CL32 HEK-293T C35(1.04)  LDD1625  [5]
 LDCM0422  CL33 HEK-293T C35(0.78)  LDD1626  [5]
 LDCM0423  CL34 HEK-293T C35(0.92)  LDD1627  [5]
 LDCM0424  CL35 HEK-293T C35(1.05)  LDD1628  [5]
 LDCM0425  CL36 HEK-293T C35(0.98)  LDD1629  [5]
 LDCM0426  CL37 HEK-293T C35(1.00)  LDD1630  [5]
 LDCM0428  CL39 HEK-293T C35(0.92)  LDD1632  [5]
 LDCM0429  CL4 HCT 116 C35(0.85)  LDD0746  [2]
 LDCM0430  CL40 HEK-293T C35(1.10)  LDD1634  [5]
 LDCM0431  CL41 HEK-293T C35(0.88)  LDD1635  [5]
 LDCM0432  CL42 HEK-293T C35(0.95)  LDD1636  [5]
 LDCM0433  CL43 HEK-293T C35(1.05)  LDD1637  [5]
 LDCM0434  CL44 HEK-293T C35(1.02)  LDD1638  [5]
 LDCM0435  CL45 HEK-293T C35(0.93)  LDD1639  [5]
 LDCM0436  CL46 HCT 116 C35(1.01)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C35(1.04)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C35(1.32)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C35(0.92)  LDD0756  [2]
 LDCM0440  CL5 HCT 116 C35(1.01)  LDD0757  [2]
 LDCM0441  CL50 HCT 116 C35(0.95)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C35(1.26)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C35(1.07)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C35(1.03)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C35(0.93)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C35(0.93)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C35(1.05)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C35(0.94)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C35(0.99)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C35(0.88)  LDD0767  [2]
 LDCM0451  CL6 HCT 116 C35(1.16)  LDD0768  [2]
 LDCM0452  CL60 HCT 116 C35(0.95)  LDD0769  [2]
 LDCM0453  CL61 HEK-293T C35(0.83)  LDD1656  [5]
 LDCM0454  CL62 HEK-293T C35(0.99)  LDD1657  [5]
 LDCM0455  CL63 HEK-293T C35(0.97)  LDD1658  [5]
 LDCM0456  CL64 HEK-293T C35(0.80)  LDD1659  [5]
 LDCM0457  CL65 HEK-293T C35(0.88)  LDD1660  [5]
 LDCM0458  CL66 HEK-293T C35(0.88)  LDD1661  [5]
 LDCM0459  CL67 HEK-293T C35(0.94)  LDD1662  [5]
 LDCM0460  CL68 HEK-293T C35(0.98)  LDD1663  [5]
 LDCM0461  CL69 HEK-293T C35(0.86)  LDD1664  [5]
 LDCM0462  CL7 HCT 116 C35(1.41)  LDD0779  [2]
 LDCM0463  CL70 HEK-293T C35(0.92)  LDD1666  [5]
 LDCM0464  CL71 HEK-293T C35(1.00)  LDD1667  [5]
 LDCM0465  CL72 HEK-293T C35(0.95)  LDD1668  [5]
 LDCM0466  CL73 HEK-293T C35(0.90)  LDD1669  [5]
 LDCM0467  CL74 HEK-293T C35(0.96)  LDD1670  [5]
 LDCM0469  CL76 HEK-293T C35(0.91)  LDD1067  [2]
 LDCM0470  CL77 HEK-293T C35(1.32)  LDD1068  [2]
 LDCM0471  CL78 HEK-293T C35(1.44)  LDD1069  [2]
 LDCM0472  CL79 HEK-293T C35(1.25)  LDD1070  [2]
 LDCM0473  CL8 HCT 116 C35(1.32)  LDD0790  [2]
 LDCM0474  CL80 HEK-293T C35(1.02)  LDD1072  [2]
 LDCM0475  CL81 HEK-293T C35(1.27)  LDD1073  [2]
 LDCM0476  CL82 HEK-293T C35(1.05)  LDD1074  [2]
 LDCM0477  CL83 HEK-293T C35(1.14)  LDD1075  [2]
 LDCM0478  CL84 HEK-293T C35(1.31)  LDD1076  [2]
 LDCM0479  CL85 HEK-293T C35(1.44)  LDD1077  [2]
 LDCM0480  CL86 HEK-293T C35(1.87)  LDD1078  [2]
 LDCM0481  CL87 HEK-293T C35(0.99)  LDD1079  [2]
 LDCM0482  CL88 HEK-293T C35(1.11)  LDD1080  [2]
 LDCM0483  CL89 HEK-293T C35(1.41)  LDD1081  [2]
 LDCM0484  CL9 HCT 116 C35(0.95)  LDD0801  [2]
 LDCM0485  CL90 HEK-293T C35(0.89)  LDD1083  [2]
 LDCM0486  CL91 HCT 116 C35(1.24)  LDD0803  [2]
 LDCM0487  CL92 HCT 116 C35(1.04)  LDD0804  [2]
 LDCM0488  CL93 HCT 116 C35(0.97)  LDD0805  [2]
 LDCM0489  CL94 HCT 116 C35(0.97)  LDD0806  [2]
 LDCM0490  CL95 HCT 116 C35(0.98)  LDD0807  [2]
 LDCM0491  CL96 HCT 116 C35(1.17)  LDD0808  [2]
 LDCM0492  CL97 HCT 116 C35(1.13)  LDD0809  [2]
 LDCM0493  CL98 HCT 116 C35(1.16)  LDD0810  [2]
 LDCM0494  CL99 HCT 116 C35(1.12)  LDD0811  [2]
 LDCM0495  E2913 HEK-293T C35(0.89)  LDD1698  [5]
 LDCM0468  Fragment33 HEK-293T C35(0.92)  LDD1671  [5]
 LDCM0427  Fragment51 HEK-293T C35(0.96)  LDD1631  [5]
 LDCM0022  KB02 HEK-293T C35(0.95)  LDD1492  [5]
 LDCM0023  KB03 HEK-293T C35(0.91)  LDD1497  [5]
 LDCM0024  KB05 MKN-1 C61(1.03)  LDD3331  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
tRNA-splicing endonuclease subunit Sen15 (TSEN15) SEN15 family Q8WW01

References

1 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
4 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
5 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
6 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840