Details of the Target

General Information of Target

Target ID LDTP09078
Target Name Zinc finger protein 114 (ZNF114)
Gene Name ZNF114
Gene ID 163071
Synonyms
Zinc finger protein 114
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSQDSVTFADVAVNFTKEEWTLLDPAQRNLYRDVMLENSRNLAFIDWATPCKTKDATPQP
DILPKRTFPEANRVCLTSISSQHSTLREDWRCPKTEEPHRQGVNNVKPPAVAPEKDESPV
SICEDHEMRNHSKPTCRLVPSQGDSIRQCILTRDSSIFKYNPVLNDSQKTHENNEDDGVL
GWNIQWVPCGRKTELKSSTWTGSQNTVHHIRDEIDTGANRHQRNPFGKAFREDGSLRAHN
THGREKMYDFTQCENTSRNNSIHAMQMQLYTAETNKKDCQTGATSANAPNSGSHKSHCTG
EKTHKCPECGRAFFYQSFLMRHMKIHTGEKPYECGKCGKAFRYSLHLNKHLRKHVVQKKP
YECEECGKVIRESSKYTHIRSHTGEKPYKCKTCGKDFAKSSGLKKHLKTHKDEKPCE
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q8NC26
Ensemble ID
ENST00000315849.5
HGNC ID
HGNC:12894

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HCT116 SNV: p.K305R .
HCT15 SNV: p.H304Y .
MOLT4 SNV: p.H322Y .
NCIH82 SNV: p.V356A .
SUPT1 Insertion: p.V103GfsTer3 .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		C136(0.00); C279(0.00); C298(0.00)  LDD0241  [1]
AHL-Pu-1
 Probe Info  		C75(5.01); C298(3.34)  LDD0170  [2]
DBIA
 Probe Info  		C51(1.11)  LDD0531  [3]
NAIA_5
 Probe Info  		C279(0.00); C75(0.00)  LDD2224  [4]
W1
 Probe Info  		C51(0.00); C298(0.00); C253(0.00); C416(0.00)  LDD0236  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA DM93 C75(5.01); C298(3.34)  LDD0170  [2]
 LDCM0026  4SU-RNA+native RNA DM93 C75(5.60); C298(6.85)  LDD0171  [2]
 LDCM0214  AC1 HCT 116 C51(1.11)  LDD0531  [3]
 LDCM0230  AC113 HCT 116 C363(0.77); C366(0.77); C51(1.08)  LDD0547  [3]
 LDCM0231  AC114 HCT 116 C363(0.64); C366(0.64); C51(0.91)  LDD0548  [3]
 LDCM0232  AC115 HCT 116 C363(0.63); C366(0.63); C51(1.15)  LDD0549  [3]
 LDCM0233  AC116 HCT 116 C363(0.85); C366(0.85); C51(1.04)  LDD0550  [3]
 LDCM0234  AC117 HCT 116 C363(0.90); C366(0.90); C51(0.98)  LDD0551  [3]
 LDCM0235  AC118 HCT 116 C363(0.51); C366(0.51); C51(1.05)  LDD0552  [3]
 LDCM0236  AC119 HCT 116 C363(0.63); C366(0.63); C51(1.03)  LDD0553  [3]
 LDCM0238  AC120 HCT 116 C363(0.71); C366(0.71); C51(1.06)  LDD0555  [3]
 LDCM0239  AC121 HCT 116 C363(0.64); C366(0.64); C51(0.88)  LDD0556  [3]
 LDCM0240  AC122 HCT 116 C363(0.62); C366(0.62); C51(0.96)  LDD0557  [3]
 LDCM0241  AC123 HCT 116 C363(0.46); C366(0.46); C51(0.65)  LDD0558  [3]
 LDCM0242  AC124 HCT 116 C363(0.93); C366(0.93); C51(0.95)  LDD0559  [3]
 LDCM0243  AC125 HCT 116 C363(0.72); C366(0.72); C51(1.23)  LDD0560  [3]
 LDCM0244  AC126 HCT 116 C363(0.53); C366(0.53); C51(1.18)  LDD0561  [3]
 LDCM0245  AC127 HCT 116 C363(0.60); C366(0.60); C51(0.99)  LDD0562  [3]
 LDCM0276  AC17 PaTu 8988t C51(0.93)  LDD1155  [3]
 LDCM0277  AC18 PaTu 8988t C51(1.13)  LDD1156  [3]
 LDCM0278  AC19 PaTu 8988t C51(0.87)  LDD1157  [3]
 LDCM0279  AC2 HCT 116 C51(1.16)  LDD0596  [3]
 LDCM0280  AC20 PaTu 8988t C51(1.11)  LDD1159  [3]
 LDCM0281  AC21 PaTu 8988t C51(1.24)  LDD1160  [3]
 LDCM0282  AC22 PaTu 8988t C51(1.31)  LDD1161  [3]
 LDCM0283  AC23 PaTu 8988t C51(1.72)  LDD1162  [3]
 LDCM0284  AC24 PaTu 8988t C51(1.58)  LDD1163  [3]
 LDCM0285  AC25 PaTu 8988t C189(0.97); C51(0.90)  LDD1164  [3]
 LDCM0286  AC26 PaTu 8988t C189(1.12); C51(1.00)  LDD1165  [3]
 LDCM0287  AC27 PaTu 8988t C189(1.03); C51(0.99)  LDD1166  [3]
 LDCM0288  AC28 PaTu 8988t C189(1.49); C51(1.08)  LDD1167  [3]
 LDCM0289  AC29 PaTu 8988t C189(0.92); C51(1.01)  LDD1168  [3]
 LDCM0290  AC3 HCT 116 C51(1.05)  LDD0607  [3]
 LDCM0291  AC30 PaTu 8988t C189(0.89); C51(0.94)  LDD1170  [3]
 LDCM0292  AC31 PaTu 8988t C189(0.92); C51(0.94)  LDD1171  [3]
 LDCM0293  AC32 PaTu 8988t C189(0.96); C51(1.21)  LDD1172  [3]
 LDCM0294  AC33 PaTu 8988t C189(1.44); C51(1.22)  LDD1173  [3]
 LDCM0295  AC34 PaTu 8988t C189(0.97); C51(1.29)  LDD1174  [3]
 LDCM0296  AC35 PaTu 8988t C51(1.30)  LDD1175  [3]
 LDCM0297  AC36 PaTu 8988t C51(1.26)  LDD1176  [3]
 LDCM0298  AC37 PaTu 8988t C51(1.25)  LDD1177  [3]
 LDCM0299  AC38 PaTu 8988t C51(1.28)  LDD1178  [3]
 LDCM0300  AC39 PaTu 8988t C51(1.47)  LDD1179  [3]
 LDCM0301  AC4 HCT 116 C51(1.01)  LDD0618  [3]
 LDCM0302  AC40 PaTu 8988t C51(1.58)  LDD1181  [3]
 LDCM0303  AC41 PaTu 8988t C51(1.33)  LDD1182  [3]
 LDCM0304  AC42 PaTu 8988t C51(1.65)  LDD1183  [3]
 LDCM0305  AC43 PaTu 8988t C51(1.18)  LDD1184  [3]
 LDCM0306  AC44 PaTu 8988t C51(1.70)  LDD1185  [3]
 LDCM0307  AC45 PaTu 8988t C51(1.49)  LDD1186  [3]
 LDCM0312  AC5 HCT 116 C51(0.94)  LDD0629  [3]
 LDCM0320  AC57 HCT 116 C363(1.11); C366(1.11)  LDD0637  [3]
 LDCM0321  AC58 HCT 116 C363(1.12); C366(1.12)  LDD0638  [3]
 LDCM0322  AC59 HCT 116 C363(1.46); C366(1.46)  LDD0639  [3]
 LDCM0324  AC60 HCT 116 C363(1.77); C366(1.77)  LDD0641  [3]
 LDCM0325  AC61 HCT 116 C363(1.18); C366(1.18)  LDD0642  [3]
 LDCM0326  AC62 HCT 116 C363(1.23); C366(1.23)  LDD0643  [3]
 LDCM0327  AC63 HCT 116 C363(1.07); C366(1.07)  LDD0644  [3]
 LDCM0328  AC64 HCT 116 C363(1.67); C366(1.67)  LDD0645  [3]
 LDCM0329  AC65 HCT 116 C363(1.48); C366(1.48)  LDD0646  [3]
 LDCM0330  AC66 HCT 116 C363(1.28); C366(1.28)  LDD0647  [3]
 LDCM0331  AC67 HCT 116 C363(1.27); C366(1.27)  LDD0648  [3]
 LDCM0332  AC68 HCT 116 C363(1.14); C366(1.14)  LDD0649  [3]
 LDCM0333  AC69 HCT 116 C363(1.33); C366(1.33)  LDD0650  [3]
 LDCM0335  AC70 HCT 116 C363(0.87); C366(0.87)  LDD0652  [3]
 LDCM0336  AC71 HCT 116 C363(0.92); C366(0.92)  LDD0653  [3]
 LDCM0337  AC72 HCT 116 C363(1.15); C366(1.15)  LDD0654  [3]
 LDCM0338  AC73 HCT 116 C363(1.76); C366(1.76)  LDD0655  [3]
 LDCM0339  AC74 HCT 116 C363(1.47); C366(1.47)  LDD0656  [3]
 LDCM0340  AC75 HCT 116 C363(1.56); C366(1.56)  LDD0657  [3]
 LDCM0341  AC76 HCT 116 C363(0.97); C366(0.97)  LDD0658  [3]
 LDCM0342  AC77 HCT 116 C363(2.05); C366(2.05)  LDD0659  [3]
 LDCM0343  AC78 HCT 116 C363(1.06); C366(1.06)  LDD0660  [3]
 LDCM0344  AC79 HCT 116 C363(1.01); C366(1.01)  LDD0661  [3]
 LDCM0346  AC80 HCT 116 C363(1.01); C366(1.01)  LDD0663  [3]
 LDCM0347  AC81 HCT 116 C363(0.93); C366(0.93)  LDD0664  [3]
 LDCM0348  AC82 HCT 116 C363(1.40); C366(1.40)  LDD0665  [3]
 LDCM0349  AC83 HCT 116 C51(0.68)  LDD0666  [3]
 LDCM0350  AC84 HCT 116 C51(0.82)  LDD0667  [3]
 LDCM0351  AC85 HCT 116 C51(0.68)  LDD0668  [3]
 LDCM0352  AC86 HCT 116 C51(0.70)  LDD0669  [3]
 LDCM0353  AC87 HCT 116 C51(0.69)  LDD0670  [3]
 LDCM0354  AC88 HCT 116 C51(0.78)  LDD0671  [3]
 LDCM0355  AC89 HCT 116 C51(0.72)  LDD0672  [3]
 LDCM0357  AC90 HCT 116 C51(0.85)  LDD0674  [3]
 LDCM0358  AC91 HCT 116 C51(0.73)  LDD0675  [3]
 LDCM0359  AC92 HCT 116 C51(0.66)  LDD0676  [3]
 LDCM0360  AC93 HCT 116 C51(0.67)  LDD0677  [3]
 LDCM0361  AC94 HCT 116 C51(0.65)  LDD0678  [3]
 LDCM0362  AC95 HCT 116 C51(0.75)  LDD0679  [3]
 LDCM0363  AC96 HCT 116 C51(0.68)  LDD0680  [3]
 LDCM0364  AC97 HCT 116 C51(0.67)  LDD0681  [3]
 LDCM0632  CL-Sc Hep-G2 C51(3.18); C279(0.83)  LDD2227  [4]
 LDCM0367  CL1 HCT 116 C363(0.48); C366(0.48)  LDD0684  [3]
 LDCM0368  CL10 HCT 116 C363(0.60); C366(0.60)  LDD0685  [3]
 LDCM0369  CL100 HCT 116 C51(1.13)  LDD0686  [3]
 LDCM0374  CL105 PaTu 8988t C51(1.15)  LDD1253  [3]
 LDCM0375  CL106 PaTu 8988t C51(1.07)  LDD1254  [3]
 LDCM0376  CL107 PaTu 8988t C51(1.06)  LDD1255  [3]
 LDCM0377  CL108 PaTu 8988t C51(1.09)  LDD1256  [3]
 LDCM0378  CL109 PaTu 8988t C51(1.38)  LDD1257  [3]
 LDCM0379  CL11 HCT 116 C363(0.94); C366(0.94)  LDD0696  [3]
 LDCM0380  CL110 PaTu 8988t C51(1.63)  LDD1259  [3]
 LDCM0381  CL111 PaTu 8988t C51(1.35)  LDD1260  [3]
 LDCM0382  CL112 PaTu 8988t C189(0.69); C51(1.00)  LDD1261  [3]
 LDCM0383  CL113 PaTu 8988t C189(0.79); C51(1.04)  LDD1262  [3]
 LDCM0384  CL114 PaTu 8988t C189(0.85); C51(0.95)  LDD1263  [3]
 LDCM0385  CL115 PaTu 8988t C189(1.00); C51(1.03)  LDD1264  [3]
 LDCM0386  CL116 PaTu 8988t C189(0.76); C51(1.18)  LDD1265  [3]
 LDCM0387  CL117 PaTu 8988t C51(1.24)  LDD1266  [3]
 LDCM0388  CL118 PaTu 8988t C51(1.68)  LDD1267  [3]
 LDCM0389  CL119 PaTu 8988t C51(1.51)  LDD1268  [3]
 LDCM0390  CL12 HCT 116 C363(0.84); C366(0.84)  LDD0707  [3]
 LDCM0391  CL120 PaTu 8988t C51(1.20)  LDD1270  [3]
 LDCM0396  CL125 HCT 116 C363(0.79); C366(0.79)  LDD0713  [3]
 LDCM0397  CL126 HCT 116 C363(1.20); C366(1.20)  LDD0714  [3]
 LDCM0398  CL127 HCT 116 C363(1.15); C366(1.15)  LDD0715  [3]
 LDCM0399  CL128 HCT 116 C363(1.38); C366(1.38)  LDD0716  [3]
 LDCM0400  CL13 HCT 116 C363(0.85); C366(0.85)  LDD0717  [3]
 LDCM0401  CL14 HCT 116 C363(0.72); C366(0.72)  LDD0718  [3]
 LDCM0402  CL15 HCT 116 C363(0.81); C366(0.81)  LDD0719  [3]
 LDCM0403  CL16 HCT 116 C363(1.09); C366(1.09); C51(1.14)  LDD0720  [3]
 LDCM0404  CL17 HCT 116 C363(0.82); C366(0.82); C51(0.95)  LDD0721  [3]
 LDCM0405  CL18 HCT 116 C363(1.08); C366(1.08); C51(1.22)  LDD0722  [3]
 LDCM0406  CL19 HCT 116 C363(1.11); C366(1.11); C51(1.17)  LDD0723  [3]
 LDCM0407  CL2 HCT 116 C363(0.60); C366(0.60)  LDD0724  [3]
 LDCM0408  CL20 HCT 116 C51(1.17); C363(1.33); C366(1.33)  LDD0725  [3]
 LDCM0409  CL21 HCT 116 C51(1.05); C363(1.16); C366(1.16)  LDD0726  [3]
 LDCM0410  CL22 HCT 116 C51(1.33); C363(1.43); C366(1.43)  LDD0727  [3]
 LDCM0411  CL23 HCT 116 C363(1.18); C366(1.18); C51(1.29)  LDD0728  [3]
 LDCM0412  CL24 HCT 116 C363(1.41); C366(1.41); C51(1.34)  LDD0729  [3]
 LDCM0413  CL25 HCT 116 C363(1.20); C366(1.20); C51(1.16)  LDD0730  [3]
 LDCM0414  CL26 HCT 116 C363(1.18); C366(1.18); C51(1.20)  LDD0731  [3]
 LDCM0415  CL27 HCT 116 C363(1.11); C366(1.11); C51(1.23)  LDD0732  [3]
 LDCM0416  CL28 HCT 116 C363(1.34); C366(1.34); C51(1.08)  LDD0733  [3]
 LDCM0417  CL29 HCT 116 C363(1.36); C366(1.36); C51(1.17)  LDD0734  [3]
 LDCM0418  CL3 HCT 116 C363(0.57); C366(0.57)  LDD0735  [3]
 LDCM0419  CL30 HCT 116 C363(1.16); C366(1.16); C51(1.24)  LDD0736  [3]
 LDCM0420  CL31 HCT 116 C51(0.69)  LDD0737  [3]
 LDCM0421  CL32 HCT 116 C51(1.02)  LDD0738  [3]
 LDCM0422  CL33 HCT 116 C51(0.92)  LDD0739  [3]
 LDCM0423  CL34 HCT 116 C51(0.94)  LDD0740  [3]
 LDCM0424  CL35 HCT 116 C51(1.01)  LDD0741  [3]
 LDCM0425  CL36 HCT 116 C51(0.83)  LDD0742  [3]
 LDCM0426  CL37 HCT 116 C51(1.11)  LDD0743  [3]
 LDCM0428  CL39 HCT 116 C51(0.96)  LDD0745  [3]
 LDCM0429  CL4 HCT 116 C363(0.75); C366(0.75)  LDD0746  [3]
 LDCM0430  CL40 HCT 116 C51(0.86)  LDD0747  [3]
 LDCM0431  CL41 HCT 116 C51(0.96)  LDD0748  [3]
 LDCM0432  CL42 HCT 116 C51(1.01)  LDD0749  [3]
 LDCM0433  CL43 HCT 116 C51(0.94)  LDD0750  [3]
 LDCM0434  CL44 HCT 116 C51(0.96)  LDD0751  [3]
 LDCM0435  CL45 HCT 116 C51(0.81)  LDD0752  [3]
 LDCM0440  CL5 HCT 116 C363(0.75); C366(0.75)  LDD0757  [3]
 LDCM0451  CL6 HCT 116 C363(0.91); C366(0.91)  LDD0768  [3]
 LDCM0453  CL61 HCT 116 C51(0.93)  LDD0770  [3]
 LDCM0454  CL62 HCT 116 C51(0.97)  LDD0771  [3]
 LDCM0455  CL63 HCT 116 C51(1.02)  LDD0772  [3]
 LDCM0456  CL64 HCT 116 C51(1.01)  LDD0773  [3]
 LDCM0457  CL65 HCT 116 C51(0.98)  LDD0774  [3]
 LDCM0458  CL66 HCT 116 C51(1.10)  LDD0775  [3]
 LDCM0459  CL67 HCT 116 C51(1.01)  LDD0776  [3]
 LDCM0460  CL68 HCT 116 C51(1.01)  LDD0777  [3]
 LDCM0461  CL69 HCT 116 C51(1.07)  LDD0778  [3]
 LDCM0462  CL7 HCT 116 C363(0.79); C366(0.79)  LDD0779  [3]
 LDCM0463  CL70 HCT 116 C51(0.94)  LDD0780  [3]
 LDCM0464  CL71 HCT 116 C51(1.08)  LDD0781  [3]
 LDCM0465  CL72 HCT 116 C51(0.89)  LDD0782  [3]
 LDCM0466  CL73 HCT 116 C51(0.93)  LDD0783  [3]
 LDCM0467  CL74 HCT 116 C51(1.19)  LDD0784  [3]
 LDCM0469  CL76 HCT 116 C363(0.70); C366(0.70)  LDD0786  [3]
 LDCM0470  CL77 HCT 116 C363(0.62); C366(0.62)  LDD0787  [3]
 LDCM0471  CL78 HCT 116 C363(0.66); C366(0.66)  LDD0788  [3]
 LDCM0472  CL79 HCT 116 C363(0.90); C366(0.90)  LDD0789  [3]
 LDCM0473  CL8 HCT 116 C363(0.78); C366(0.78)  LDD0790  [3]
 LDCM0474  CL80 HCT 116 C363(0.67); C366(0.67)  LDD0791  [3]
 LDCM0475  CL81 HCT 116 C363(0.74); C366(0.74)  LDD0792  [3]
 LDCM0476  CL82 HCT 116 C363(0.80); C366(0.80)  LDD0793  [3]
 LDCM0477  CL83 HCT 116 C363(0.75); C366(0.75)  LDD0794  [3]
 LDCM0478  CL84 HCT 116 C363(0.66); C366(0.66)  LDD0795  [3]
 LDCM0479  CL85 HCT 116 C363(0.79); C366(0.79)  LDD0796  [3]
 LDCM0480  CL86 HCT 116 C363(0.72); C366(0.72)  LDD0797  [3]
 LDCM0481  CL87 HCT 116 C363(0.70); C366(0.70)  LDD0798  [3]
 LDCM0482  CL88 HCT 116 C363(0.66); C366(0.66)  LDD0799  [3]
 LDCM0483  CL89 HCT 116 C363(0.74); C366(0.74)  LDD0800  [3]
 LDCM0484  CL9 HCT 116 C363(0.73); C366(0.73)  LDD0801  [3]
 LDCM0485  CL90 HCT 116 C363(0.52); C366(0.52)  LDD0802  [3]
 LDCM0486  CL91 HCT 116 C51(1.06)  LDD0803  [3]
 LDCM0487  CL92 HCT 116 C51(1.05)  LDD0804  [3]
 LDCM0488  CL93 HCT 116 C51(0.94)  LDD0805  [3]
 LDCM0489  CL94 HCT 116 C51(1.07)  LDD0806  [3]
 LDCM0490  CL95 HCT 116 C51(0.97)  LDD0807  [3]
 LDCM0491  CL96 HCT 116 C51(1.04)  LDD0808  [3]
 LDCM0492  CL97 HCT 116 C51(0.97)  LDD0809  [3]
 LDCM0493  CL98 HCT 116 C51(1.16)  LDD0810  [3]
 LDCM0494  CL99 HCT 116 C51(1.04)  LDD0811  [3]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C279(1.49)  LDD1702  [5]
 LDCM0468  Fragment33 HCT 116 C51(0.96)  LDD0785  [3]
 LDCM0427  Fragment51 HCT 116 C51(0.83)  LDD0744  [3]
 LDCM0022  KB02 G-361 C51(3.63)  LDD2329  [6]
 LDCM0023  KB03 MDA-MB-231 C279(2.21)  LDD1701  [5]
 LDCM0024  KB05 NCI-H1975 C54(4.99)  LDD3352  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Tubulin polymerization-promoting protein (TPPP) TPPP family O94811
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Kelch-like protein 2 (KLHL2) . O95198
Transcription factor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Zinc finger protein 114 (ZNF114) Krueppel C2H2-type zinc-finger protein family Q8NC26
Zinc finger protein 8 (ZNF8) Krueppel C2H2-type zinc-finger protein family P17098
Other
Click To Hide/Show 6 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Keratin-associated protein 10-6 (KRTAP10-6) KRTAP type 10 family P60371
Ensconsin (MAP7) MAP7 family Q14244
Suppressor of fused homolog (SUFU) SUFU family Q9UMX1
CAP-Gly domain-containing linker protein 4 (CLIP4) . Q8N3C7
Centrosomal AT-AC splicing factor (CENATAC) . Q86UT8
Protein moonraker (KIAA0753) . Q2KHM9

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
2 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
5 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
6 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840