Details of the Target

General Information of Target

Target ID LDTP08992
Target Name Centrosomal protein of 120 kDa (CEP120)
Gene Name CEP120
Gene ID 153241
Synonyms
CCDC100; Centrosomal protein of 120 kDa; Cep120; Coiled-coil domain-containing protein 100
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MVSKSDQLLIVVSILEGRHFPKRPKHMLVVEAKFDGEQLATDPVDHTDQPEFATELAWEI
DRKALHQHRLQRTPIKLQCFALDPVTSAKETIGYIVLDLRTAQETKQAPKWYQLLSNKYT
KFKSEIQISIALETDTKPPVDSFKAKGAPPRDGKVPAILAGLDPRDIVAVLNEEGGYHQI
GPAEYCTDSFIMSVTIAFATQLEQLIPCTMKLPERQPEFFFYYSLLGNDVTNEPFNDLIN
PNFEPERASVRIRSSVEILRVYLALQSKLQIHLCCGDQSLGSTEIPLTGLLKKGSTEINQ
HPVTVEGAFTLDPPNRAKQKLAPIPVELAPTVGVSVALQREGIDSQSLIELKTQNEHEPE
HSKKKVLTPIKEKTLTGPKSPTVSPVPSHNQSPPTKDDATESEVESLQYDKDTKPNPKAS
SSVPASLAQLVTTSNASEVASGQKIAVPATSHHFCFSIDLRSIHALEIGFPINCILRYSY
PFFGSAAPIMTNPPVEVRKNMEVFLPQSYCAFDFATMPHQLQDTFLRIPLLVELWHKDKM
SKDLLLGIARIQLSNILSSEKTRFLGSNGEQCWRQTYSESVPVIAAQGSNNRIADLSYTV
TLEDYGLVKMREIFISDSSQGVSAVQQKPSSLPPAPCPSEIQTEPRETLEYKAALELEMW
KEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLE
KREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDK
HRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKS
KLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQEL
LDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLMRTGV
YNHEDRIISELDRQIREILAKSNASN
Target Bioclass
Other
Family
CEP120 family
Subcellular location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Function
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. Required for centriole duplication and maturation during mitosis and subsequent ciliogenesis. Required for the recruitment of CEP295 to the proximal end of new-born centrioles at the centriolar microtubule wall during early S phase in a PLK4-dependent manner.
Uniprot ID
Q8N960
Ensemble ID
ENST00000306467.10
HGNC ID
HGNC:26690

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
22RV1 Deletion: p.T562LfsTer4
SNV: p.Y509S		 .
AU565 SNV: p.T209I .
DU145 SNV: p.M1? .
HEC1 SNV: p.L15I .
IM95 SNV: p.Q847Ter .
KYSE410 SNV: p.M680I .
NCIH2286 SNV: p.G442Ter .
NCIH2291 SNV: p.Y605C .
OVK18 SNV: p.T296I .
RPMI7951 SNV: p.S420R .
SW1271 SNV: p.R909M .
YSCCC SNV: p.A131V .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C572(1.22)  LDD0531  [1]
YN-1
 Probe Info  		N.A.  LDD0447  [2]
PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STS-1
 Probe Info  		N.A.  LDD0137  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C572(1.22)  LDD0531  [1]
 LDCM0215  AC10 HCT 116 C572(1.04)  LDD0532  [1]
 LDCM0216  AC100 HCT 116 C572(0.72)  LDD0533  [1]
 LDCM0217  AC101 HCT 116 C572(0.77)  LDD0534  [1]
 LDCM0218  AC102 HCT 116 C572(0.47)  LDD0535  [1]
 LDCM0219  AC103 HCT 116 C572(1.24)  LDD0536  [1]
 LDCM0220  AC104 HCT 116 C572(0.66)  LDD0537  [1]
 LDCM0221  AC105 HCT 116 C572(0.76)  LDD0538  [1]
 LDCM0222  AC106 HCT 116 C572(1.24)  LDD0539  [1]
 LDCM0223  AC107 HCT 116 C572(0.77)  LDD0540  [1]
 LDCM0224  AC108 HCT 116 C572(0.83)  LDD0541  [1]
 LDCM0225  AC109 HCT 116 C572(0.68)  LDD0542  [1]
 LDCM0226  AC11 HCT 116 C572(0.78)  LDD0543  [1]
 LDCM0227  AC110 HCT 116 C572(0.59)  LDD0544  [1]
 LDCM0228  AC111 HCT 116 C572(1.23)  LDD0545  [1]
 LDCM0229  AC112 HCT 116 C572(0.92)  LDD0546  [1]
 LDCM0237  AC12 HCT 116 C572(0.71)  LDD0554  [1]
 LDCM0259  AC14 HCT 116 C572(1.04)  LDD0576  [1]
 LDCM0270  AC15 HCT 116 C572(0.88)  LDD0587  [1]
 LDCM0276  AC17 HCT 116 C572(0.89)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C572(0.80)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C572(0.73)  LDD0595  [1]
 LDCM0279  AC2 HCT 116 C572(1.05)  LDD0596  [1]
 LDCM0280  AC20 HCT 116 C572(0.61)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C572(0.84)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C572(1.17)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C572(0.78)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C572(0.80)  LDD0601  [1]
 LDCM0285  AC25 HEK-293T C637(0.96)  LDD1524  [4]
 LDCM0286  AC26 HEK-293T C637(0.93)  LDD1525  [4]
 LDCM0287  AC27 HEK-293T C637(1.14)  LDD1526  [4]
 LDCM0288  AC28 HEK-293T C637(1.21)  LDD1527  [4]
 LDCM0289  AC29 HEK-293T C637(1.04)  LDD1528  [4]
 LDCM0290  AC3 HCT 116 C572(1.10)  LDD0607  [1]
 LDCM0291  AC30 HEK-293T C637(0.97)  LDD1530  [4]
 LDCM0292  AC31 HEK-293T C637(1.09)  LDD1531  [4]
 LDCM0293  AC32 HEK-293T C637(0.91)  LDD1532  [4]
 LDCM0294  AC33 HEK-293T C637(0.99)  LDD1533  [4]
 LDCM0295  AC34 HEK-293T C637(0.90)  LDD1534  [4]
 LDCM0296  AC35 HCT 116 C572(0.67)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C572(0.69)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C572(0.67)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C572(0.85)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C572(0.83)  LDD0617  [1]
 LDCM0301  AC4 HCT 116 C572(1.09)  LDD0618  [1]
 LDCM0302  AC40 HCT 116 C572(0.84)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C572(0.76)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C572(0.94)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C572(0.96)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C572(0.84)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C572(0.91)  LDD0624  [1]
 LDCM0308  AC46 HCT 116 C572(0.84)  LDD0625  [1]
 LDCM0309  AC47 HCT 116 C572(0.96)  LDD0626  [1]
 LDCM0310  AC48 HCT 116 C572(1.33)  LDD0627  [1]
 LDCM0311  AC49 HCT 116 C572(1.96)  LDD0628  [1]
 LDCM0312  AC5 HCT 116 C572(1.33)  LDD0629  [1]
 LDCM0313  AC50 HCT 116 C572(1.21)  LDD0630  [1]
 LDCM0314  AC51 HCT 116 C572(1.10)  LDD0631  [1]
 LDCM0315  AC52 HCT 116 C572(1.29)  LDD0632  [1]
 LDCM0316  AC53 HCT 116 C572(1.43)  LDD0633  [1]
 LDCM0317  AC54 HCT 116 C572(1.07)  LDD0634  [1]
 LDCM0318  AC55 HCT 116 C572(1.09)  LDD0635  [1]
 LDCM0319  AC56 HCT 116 C572(1.36)  LDD0636  [1]
 LDCM0320  AC57 PaTu 8988t C572(1.21)  LDD1199  [1]
 LDCM0321  AC58 PaTu 8988t C572(1.30)  LDD1200  [1]
 LDCM0322  AC59 PaTu 8988t C572(1.19)  LDD1201  [1]
 LDCM0323  AC6 HCT 116 C572(0.86)  LDD0640  [1]
 LDCM0324  AC60 PaTu 8988t C572(1.18)  LDD1203  [1]
 LDCM0325  AC61 PaTu 8988t C572(1.21)  LDD1204  [1]
 LDCM0326  AC62 PaTu 8988t C572(1.39)  LDD1205  [1]
 LDCM0327  AC63 PaTu 8988t C572(1.23)  LDD1206  [1]
 LDCM0328  AC64 PaTu 8988t C572(1.32)  LDD1207  [1]
 LDCM0329  AC65 PaTu 8988t C572(1.24)  LDD1208  [1]
 LDCM0330  AC66 PaTu 8988t C572(1.32)  LDD1209  [1]
 LDCM0331  AC67 PaTu 8988t C572(1.26)  LDD1210  [1]
 LDCM0332  AC68 HCT 116 C572(1.04)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C572(0.94)  LDD0650  [1]
 LDCM0334  AC7 HCT 116 C572(1.12)  LDD0651  [1]
 LDCM0335  AC70 HCT 116 C572(1.04)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C572(1.44)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C572(1.14)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C572(1.30)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C572(1.23)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C572(1.63)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C572(1.18)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C572(1.25)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C572(1.20)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C572(1.48)  LDD0661  [1]
 LDCM0345  AC8 HCT 116 C572(1.32)  LDD0662  [1]
 LDCM0346  AC80 HCT 116 C572(1.19)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C572(1.20)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C572(1.22)  LDD0665  [1]
 LDCM0349  AC83 PaTu 8988t C572(0.92)  LDD1228  [1]
 LDCM0350  AC84 PaTu 8988t C572(0.82)  LDD1229  [1]
 LDCM0351  AC85 PaTu 8988t C572(0.92)  LDD1230  [1]
 LDCM0352  AC86 PaTu 8988t C572(0.80)  LDD1231  [1]
 LDCM0353  AC87 PaTu 8988t C572(0.98)  LDD1232  [1]
 LDCM0354  AC88 PaTu 8988t C572(0.98)  LDD1233  [1]
 LDCM0355  AC89 PaTu 8988t C572(0.88)  LDD1234  [1]
 LDCM0357  AC90 PaTu 8988t C572(0.85)  LDD1236  [1]
 LDCM0358  AC91 PaTu 8988t C572(0.83)  LDD1237  [1]
 LDCM0359  AC92 PaTu 8988t C572(0.79)  LDD1238  [1]
 LDCM0360  AC93 PaTu 8988t C572(1.04)  LDD1239  [1]
 LDCM0361  AC94 PaTu 8988t C572(0.86)  LDD1240  [1]
 LDCM0362  AC95 PaTu 8988t C572(0.75)  LDD1241  [1]
 LDCM0363  AC96 PaTu 8988t C572(1.09)  LDD1242  [1]
 LDCM0364  AC97 PaTu 8988t C572(0.85)  LDD1243  [1]
 LDCM0365  AC98 HCT 116 C572(0.83)  LDD0682  [1]
 LDCM0366  AC99 HCT 116 C572(1.03)  LDD0683  [1]
 LDCM0248  AKOS034007472 HCT 116 C572(1.07)  LDD0565  [1]
 LDCM0356  AKOS034007680 HCT 116 C572(0.88)  LDD0673  [1]
 LDCM0275  AKOS034007705 HCT 116 C572(0.98)  LDD0592  [1]
 LDCM0367  CL1 HCT 116 C572(1.14)  LDD0684  [1]
 LDCM0368  CL10 HCT 116 C572(0.89)  LDD0685  [1]
 LDCM0369  CL100 HCT 116 C572(1.14)  LDD0686  [1]
 LDCM0370  CL101 HCT 116 C572(1.05)  LDD0687  [1]
 LDCM0371  CL102 HCT 116 C572(0.88)  LDD0688  [1]
 LDCM0372  CL103 HCT 116 C572(0.94)  LDD0689  [1]
 LDCM0373  CL104 HCT 116 C572(0.96)  LDD0690  [1]
 LDCM0374  CL105 HCT 116 C572(0.66)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C572(0.69)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C572(0.82)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C572(1.12)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C572(0.68)  LDD0695  [1]
 LDCM0379  CL11 HCT 116 C572(1.35)  LDD0696  [1]
 LDCM0380  CL110 HCT 116 C572(0.76)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C572(0.67)  LDD0698  [1]
 LDCM0382  CL112 HEK-293T C637(1.16)  LDD1586  [4]
 LDCM0383  CL113 HEK-293T C637(1.05)  LDD1587  [4]
 LDCM0384  CL114 HEK-293T C637(0.79); C762(1.01)  LDD1588  [4]
 LDCM0385  CL115 HEK-293T C637(1.02)  LDD1589  [4]
 LDCM0386  CL116 HEK-293T C637(0.92)  LDD1590  [4]
 LDCM0387  CL117 HCT 116 C572(1.06)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C572(0.93)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C572(0.68)  LDD0706  [1]
 LDCM0390  CL12 HCT 116 C572(1.40)  LDD0707  [1]
 LDCM0391  CL120 HCT 116 C572(0.95)  LDD0708  [1]
 LDCM0392  CL121 HCT 116 C572(0.55)  LDD0709  [1]
 LDCM0393  CL122 HCT 116 C572(1.09)  LDD0710  [1]
 LDCM0394  CL123 HCT 116 C572(0.97)  LDD0711  [1]
 LDCM0395  CL124 HCT 116 C572(1.26)  LDD0712  [1]
 LDCM0396  CL125 PaTu 8988t C572(1.21)  LDD1275  [1]
 LDCM0397  CL126 PaTu 8988t C572(1.17)  LDD1276  [1]
 LDCM0398  CL127 PaTu 8988t C572(0.93)  LDD1277  [1]
 LDCM0399  CL128 PaTu 8988t C572(1.23)  LDD1278  [1]
 LDCM0400  CL13 HCT 116 C572(1.45)  LDD0717  [1]
 LDCM0401  CL14 HCT 116 C572(1.77)  LDD0718  [1]
 LDCM0402  CL15 HCT 116 C572(1.31)  LDD0719  [1]
 LDCM0403  CL16 HCT 116 C572(0.81)  LDD0720  [1]
 LDCM0404  CL17 HCT 116 C572(0.89)  LDD0721  [1]
 LDCM0405  CL18 HCT 116 C572(1.31)  LDD0722  [1]
 LDCM0406  CL19 HCT 116 C572(0.95)  LDD0723  [1]
 LDCM0407  CL2 HCT 116 C572(1.19)  LDD0724  [1]
 LDCM0408  CL20 HCT 116 C572(0.93)  LDD0725  [1]
 LDCM0409  CL21 HCT 116 C572(1.06)  LDD0726  [1]
 LDCM0410  CL22 HCT 116 C572(1.14)  LDD0727  [1]
 LDCM0411  CL23 HCT 116 C572(0.81)  LDD0728  [1]
 LDCM0412  CL24 HCT 116 C572(0.93)  LDD0729  [1]
 LDCM0413  CL25 HCT 116 C572(0.94)  LDD0730  [1]
 LDCM0414  CL26 HCT 116 C572(0.95)  LDD0731  [1]
 LDCM0415  CL27 HCT 116 C572(1.26)  LDD0732  [1]
 LDCM0416  CL28 HCT 116 C572(0.84)  LDD0733  [1]
 LDCM0417  CL29 HCT 116 C572(1.10)  LDD0734  [1]
 LDCM0418  CL3 HCT 116 C572(1.67)  LDD0735  [1]
 LDCM0419  CL30 HCT 116 C572(1.00)  LDD0736  [1]
 LDCM0420  CL31 HCT 116 C572(1.21)  LDD0737  [1]
 LDCM0421  CL32 HCT 116 C572(0.87)  LDD0738  [1]
 LDCM0422  CL33 HCT 116 C572(1.44)  LDD0739  [1]
 LDCM0423  CL34 HCT 116 C572(1.44)  LDD0740  [1]
 LDCM0424  CL35 HCT 116 C572(0.95)  LDD0741  [1]
 LDCM0425  CL36 HCT 116 C572(1.08)  LDD0742  [1]
 LDCM0426  CL37 HCT 116 C572(2.23)  LDD0743  [1]
 LDCM0428  CL39 HCT 116 C572(0.78)  LDD0745  [1]
 LDCM0429  CL4 HCT 116 C572(1.56)  LDD0746  [1]
 LDCM0430  CL40 HCT 116 C572(1.22)  LDD0747  [1]
 LDCM0431  CL41 HCT 116 C572(1.88)  LDD0748  [1]
 LDCM0432  CL42 HCT 116 C572(1.05)  LDD0749  [1]
 LDCM0433  CL43 HCT 116 C572(1.38)  LDD0750  [1]
 LDCM0434  CL44 HCT 116 C572(0.77)  LDD0751  [1]
 LDCM0435  CL45 HCT 116 C572(0.92)  LDD0752  [1]
 LDCM0436  CL46 PaTu 8988t C572(0.81)  LDD1315  [1]
 LDCM0437  CL47 PaTu 8988t C572(0.81)  LDD1316  [1]
 LDCM0438  CL48 PaTu 8988t C572(0.75)  LDD1317  [1]
 LDCM0439  CL49 PaTu 8988t C572(0.85)  LDD1318  [1]
 LDCM0440  CL5 HCT 116 C572(1.31)  LDD0757  [1]
 LDCM0441  CL50 PaTu 8988t C572(0.90)  LDD1320  [1]
 LDCM0442  CL51 PaTu 8988t C572(0.85)  LDD1321  [1]
 LDCM0443  CL52 PaTu 8988t C572(0.89)  LDD1322  [1]
 LDCM0444  CL53 PaTu 8988t C572(0.81)  LDD1323  [1]
 LDCM0445  CL54 PaTu 8988t C572(0.80)  LDD1324  [1]
 LDCM0446  CL55 PaTu 8988t C572(0.81)  LDD1325  [1]
 LDCM0447  CL56 PaTu 8988t C572(0.80)  LDD1326  [1]
 LDCM0448  CL57 PaTu 8988t C572(0.89)  LDD1327  [1]
 LDCM0449  CL58 PaTu 8988t C572(0.86)  LDD1328  [1]
 LDCM0450  CL59 PaTu 8988t C572(0.91)  LDD1329  [1]
 LDCM0451  CL6 HCT 116 C572(1.38)  LDD0768  [1]
 LDCM0452  CL60 PaTu 8988t C572(0.86)  LDD1331  [1]
 LDCM0453  CL61 HCT 116 C572(1.55)  LDD0770  [1]
 LDCM0454  CL62 HCT 116 C572(1.08)  LDD0771  [1]
 LDCM0455  CL63 HCT 116 C572(0.86)  LDD0772  [1]
 LDCM0456  CL64 HCT 116 C572(0.96)  LDD0773  [1]
 LDCM0457  CL65 HCT 116 C572(1.17)  LDD0774  [1]
 LDCM0458  CL66 HCT 116 C572(1.11)  LDD0775  [1]
 LDCM0459  CL67 HCT 116 C572(0.88)  LDD0776  [1]
 LDCM0460  CL68 HCT 116 C572(1.11)  LDD0777  [1]
 LDCM0461  CL69 HCT 116 C572(1.49)  LDD0778  [1]
 LDCM0462  CL7 HCT 116 C572(1.18)  LDD0779  [1]
 LDCM0463  CL70 HCT 116 C572(1.07)  LDD0780  [1]
 LDCM0464  CL71 HCT 116 C572(0.94)  LDD0781  [1]
 LDCM0465  CL72 HCT 116 C572(0.96)  LDD0782  [1]
 LDCM0466  CL73 HCT 116 C572(1.33)  LDD0783  [1]
 LDCM0467  CL74 HCT 116 C572(0.96)  LDD0784  [1]
 LDCM0469  CL76 PaTu 8988t C572(0.99)  LDD1348  [1]
 LDCM0470  CL77 PaTu 8988t C572(1.04)  LDD1349  [1]
 LDCM0471  CL78 PaTu 8988t C572(1.06)  LDD1350  [1]
 LDCM0472  CL79 PaTu 8988t C572(0.85)  LDD1351  [1]
 LDCM0473  CL8 HCT 116 C572(1.90)  LDD0790  [1]
 LDCM0474  CL80 PaTu 8988t C572(1.21)  LDD1353  [1]
 LDCM0475  CL81 PaTu 8988t C572(1.21)  LDD1354  [1]
 LDCM0476  CL82 PaTu 8988t C572(0.87)  LDD1355  [1]
 LDCM0477  CL83 PaTu 8988t C572(0.95)  LDD1356  [1]
 LDCM0478  CL84 PaTu 8988t C572(1.26)  LDD1357  [1]
 LDCM0479  CL85 PaTu 8988t C572(1.18)  LDD1358  [1]
 LDCM0480  CL86 PaTu 8988t C572(1.10)  LDD1359  [1]
 LDCM0481  CL87 PaTu 8988t C572(1.14)  LDD1360  [1]
 LDCM0482  CL88 PaTu 8988t C572(1.21)  LDD1361  [1]
 LDCM0483  CL89 PaTu 8988t C572(0.87)  LDD1362  [1]
 LDCM0484  CL9 HCT 116 C572(1.48)  LDD0801  [1]
 LDCM0485  CL90 PaTu 8988t C572(0.78)  LDD1364  [1]
 LDCM0486  CL91 HCT 116 C572(1.09)  LDD0803  [1]
 LDCM0487  CL92 HCT 116 C572(1.03)  LDD0804  [1]
 LDCM0488  CL93 HCT 116 C572(0.97)  LDD0805  [1]
 LDCM0489  CL94 HCT 116 C572(1.45)  LDD0806  [1]
 LDCM0490  CL95 HCT 116 C572(1.30)  LDD0807  [1]
 LDCM0491  CL96 HCT 116 C572(1.14)  LDD0808  [1]
 LDCM0492  CL97 HCT 116 C572(1.07)  LDD0809  [1]
 LDCM0493  CL98 HCT 116 C572(1.03)  LDD0810  [1]
 LDCM0494  CL99 HCT 116 C572(1.38)  LDD0811  [1]
 LDCM0495  E2913 HEK-293T C637(0.93)  LDD1698  [4]
 LDCM0468  Fragment33 HCT 116 C572(0.86)  LDD0785  [1]
 LDCM0427  Fragment51 HCT 116 C572(1.14)  LDD0744  [1]
 LDCM0022  KB02 HEK-293T C762(0.97); C637(1.11)  LDD1492  [4]
 LDCM0023  KB03 HEK-293T C762(0.97); C637(1.24)  LDD1497  [4]
 LDCM0024  KB05 HEK-293T C762(0.99); C637(0.81)  LDD1502  [4]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Centrosomal protein of 162 kDa (CEP162) CEP162 family Q5TB80

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
3 Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8551-6. doi: 10.1002/anie.201300683. Epub 2013 Jun 10.
4 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402