Details of the Target

General Information of Target

Target ID LDTP08772
Target Name RNA exonuclease 1 homolog (REXO1)
Gene Name REXO1
Gene ID 57455
Synonyms
ELOABP1; KIAA1138; TCEB3BP1; RNA exonuclease 1 homolog; EC 3.1.-.-; Elongin-A-binding protein 1; EloA-BP1; Transcription elongation factor B polypeptide 3-binding protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLRSTGFFRAIDCPYWSGAPGGPCRRPYCHFRHRGARGSGAPGDGGEAPPAAGLGYDPYN
PELPKPPAQRENGTLGLGEEPRPDVLELELVNQAIEAVRSEVELEQRRYRELLETTREHR
SAEAPALAPRGPNASPTVGPDEDAFPLAFDYSPGSHGLLSPDAGYQPTPLAAPAEPGSKY
SLASLDRGQGRGGGGGGALEYVPKAVSQPRRHSRPVPSGKYVVDNSRPPTDLEYDPLSNY
SARHLSRASSRDERAAKRPRGSRGSEPYTPAPKKLCDPFGSCDARFSDSEDEAATVPGNE
PTTASTPKARADPEIKATGQPPSKEGLEAEGGGLRETKETAVQCDVGDLQPPPAKPASPA
QVQSSQDGGCPKEGKPKKKKTGAPPAPSCKDGAQGKDKTKDKGRGRPVEKPRADKKGPQA
SSPRRKAERPEGTKKKPSSATPVATSGKGRPDRPARRPSPTSGDSRPAAGRGPPRPLQLP
DRKSTKAPSGKLVERKARSLDEGASQDAPKLKKRALSHADLFGDESEDEAAGPGVPSVWP
SALPSLSSDSDSDSDSSLGFPEAQGPPKRLKASPPPSPAPSSSSSSSSSTSSAGADVDYS
ALEKEVDFDSDPMEECLRIFNESTSVKTEDRGRLARQPPKEEKSEEKGLSGLTTLFPGQK
RRISHLSKQGQEVEPPRRGPAVPPARPPTAQEVCYLRAQQAQRASASLLQAPARLAEKSP
SVHISAPGEKRRIAHIPNPRLAAAPTGAKRTLAASGSQSSNGPEPGGQQLKTRTLSGMAS
KTTTTIIPKRIAHSPSLQSLKKPIIPKEFGGKVPTVIRQRYLNLFIEECLKFCTSNQEAI
EKALNEEKVAYDRSPSKNIYLNVAVNTLKKLRGLAPSAVPGLSKTSGRRVVSHEVVLGGR
LAAKTSFSLSRPSSPRVEDLKGAALYSRLREYLLTQDQLKENGYPFPHPERPGGAIIFTA
EEKRPKDSSCRTCCRCGTEYLVSSSGRCIRDEECYYHWGRLRRNRVAGGWETQYMCCSAA
AGSVGCQVAKQHVQDGRKERLEGFVKTFEKELSGDTHPGIYALDCEMSYTTYGLELTRVT
VVDTDVHVVYDTFVKPDNEIVDYNTRFSGVTEADLADTSVTLRDVQAVLLSMFSADTILI
GHSLESDLLALKVIHSTVVDTSVLFPHRLGLPYKRSLRNLMADYLRQIIQDNVDGHSSSE
DAGACMHLVIWKVREDAKTKR
Target Bioclass
Enzyme
Family
REXO1/REXO3 family
Subcellular location
Nucleus
Function Seems to have no detectable effect on transcription elongation in vitro.
Uniprot ID
Q8N1G1
Ensemble ID
ENST00000170168.9
HGNC ID
HGNC:24616

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
ONAyne
 Probe Info  		K410(2.20)  LDD0274  [1]
DBIA
 Probe Info  		C276(0.95); C282(0.95); C13(0.87); C24(0.87)  LDD0078  [2]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [3]
IPM
 Probe Info  		N.A.  LDD0005  [4]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C389(1.31); C976(1.31)  LDD0812  [2]
 LDCM0215  AC10 HCT 116 C13(1.04); C24(1.04); C389(1.07)  LDD0532  [2]
 LDCM0216  AC100 HEK-293T C389(0.82); C976(0.82)  LDD0814  [2]
 LDCM0217  AC101 HEK-293T C389(1.15); C976(1.15)  LDD0815  [2]
 LDCM0218  AC102 HEK-293T C389(0.60); C976(0.60)  LDD0816  [2]
 LDCM0219  AC103 HEK-293T C389(1.20); C976(1.20)  LDD0817  [2]
 LDCM0220  AC104 HEK-293T C389(0.63); C976(0.63)  LDD0818  [2]
 LDCM0221  AC105 HEK-293T C389(1.03); C976(1.03)  LDD0819  [2]
 LDCM0222  AC106 HEK-293T C389(1.15); C976(1.15)  LDD0820  [2]
 LDCM0223  AC107 HEK-293T C389(0.74); C976(0.74)  LDD0821  [2]
 LDCM0224  AC108 HEK-293T C389(0.86); C976(0.86)  LDD0822  [2]
 LDCM0225  AC109 HEK-293T C389(0.66); C976(0.66)  LDD0823  [2]
 LDCM0226  AC11 HCT 116 C13(1.40); C24(1.40); C389(1.23)  LDD0543  [2]
 LDCM0227  AC110 HEK-293T C389(0.68); C976(0.68)  LDD0825  [2]
 LDCM0228  AC111 HEK-293T C389(1.11); C976(1.11)  LDD0826  [2]
 LDCM0229  AC112 HEK-293T C389(1.00); C976(1.00)  LDD0827  [2]
 LDCM0237  AC12 HCT 116 C13(1.20); C24(1.20); C389(0.97)  LDD0554  [2]
 LDCM0259  AC14 HCT 116 C13(1.23); C24(1.23); C389(0.98)  LDD0576  [2]
 LDCM0263  AC143 HCT 116 C13(1.51); C24(1.51)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C24(0.81); C13(1.28)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C24(0.81); C13(1.14)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C24(1.15); C13(1.36)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C24(0.77); C13(1.98)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C24(0.95); C13(1.30)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C24(0.79); C13(1.01)  LDD0586  [2]
 LDCM0270  AC15 HCT 116 C389(1.04); C13(1.20); C24(1.20)  LDD0587  [2]
 LDCM0271  AC150 HCT 116 C24(1.14); C13(1.31)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C24(1.12); C13(1.61)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C24(0.90); C13(1.38)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C24(1.00); C13(1.53)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C13(1.43); C24(0.93)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C13(1.57); C24(1.23)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C13(1.27); C24(1.18)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C13(1.89); C24(0.84)  LDD2161  [2]
 LDCM0276  AC17 HCT 116 C389(0.88)  LDD0593  [2]
 LDCM0277  AC18 HCT 116 C389(0.81)  LDD0594  [2]
 LDCM0278  AC19 HCT 116 C389(0.78)  LDD0595  [2]
 LDCM0279  AC2 HEK-293T C389(0.88); C976(0.88)  LDD0877  [2]
 LDCM0280  AC20 HCT 116 C389(1.17)  LDD0597  [2]
 LDCM0281  AC21 HCT 116 C389(0.79)  LDD0598  [2]
 LDCM0282  AC22 HCT 116 C389(0.87)  LDD0599  [2]
 LDCM0283  AC23 HCT 116 C389(0.85)  LDD0600  [2]
 LDCM0284  AC24 HCT 116 C389(0.76)  LDD0601  [2]
 LDCM0287  AC27 HEK-293T C389(0.97)  LDD1526  [6]
 LDCM0290  AC3 HEK-293T C389(1.25); C976(1.25)  LDD0888  [2]
 LDCM0296  AC35 HEK-293T C389(0.99)  LDD1535  [6]
 LDCM0301  AC4 HEK-293T C389(0.96); C976(0.96)  LDD0899  [2]
 LDCM0305  AC43 HEK-293T C389(0.95)  LDD1544  [6]
 LDCM0312  AC5 HEK-293T C389(0.65); C976(0.65)  LDD0910  [2]
 LDCM0314  AC51 HEK-293T C389(1.00)  LDD1553  [6]
 LDCM0320  AC57 HCT 116 C389(1.16)  LDD0637  [2]
 LDCM0321  AC58 HCT 116 C389(1.20)  LDD0638  [2]
 LDCM0322  AC59 HCT 116 C389(1.29)  LDD0639  [2]
 LDCM0323  AC6 HCT 116 C389(1.02); C13(1.08); C24(1.08)  LDD0640  [2]
 LDCM0324  AC60 HCT 116 C389(1.81)  LDD0641  [2]
 LDCM0325  AC61 HCT 116 C389(1.32)  LDD0642  [2]
 LDCM0326  AC62 HCT 116 C389(1.26)  LDD0643  [2]
 LDCM0327  AC63 HCT 116 C389(2.09)  LDD0644  [2]
 LDCM0328  AC64 HCT 116 C389(1.64)  LDD0645  [2]
 LDCM0329  AC65 HCT 116 C389(1.39)  LDD0646  [2]
 LDCM0330  AC66 HCT 116 C389(1.58)  LDD0647  [2]
 LDCM0331  AC67 HCT 116 C389(1.97)  LDD0648  [2]
 LDCM0332  AC68 HCT 116 C13(0.77); C24(0.77); C389(0.89)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C13(0.77); C24(0.77); C389(1.13)  LDD0650  [2]
 LDCM0334  AC7 HCT 116 C389(0.93); C13(1.49); C24(1.49)  LDD0651  [2]
 LDCM0335  AC70 HCT 116 C13(0.73); C24(0.73); C389(1.15)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C13(0.54); C24(0.54); C389(0.95)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C13(1.07); C24(1.07); C389(1.08)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C13(1.01); C24(1.01); C389(1.57)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C13(0.84); C24(0.84); C389(1.48)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C13(1.15); C24(1.15); C389(2.03)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C13(0.81); C24(0.81); C389(1.23)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C13(0.99); C24(0.99); C389(1.23)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C389(1.05); C13(1.11); C24(1.11)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C13(0.98); C24(0.98); C389(1.03)  LDD0661  [2]
 LDCM0345  AC8 HCT 116 C389(1.07); C13(1.29); C24(1.29)  LDD0662  [2]
 LDCM0346  AC80 HCT 116 C13(0.93); C24(0.93); C389(1.18)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C389(0.76); C13(1.06); C24(1.06)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C13(0.84); C24(0.84); C389(2.15)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C13(1.00); C24(1.00)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C13(0.99); C24(0.99)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C13(0.83); C24(0.83)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C13(0.83); C24(0.83)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C13(0.85); C24(0.85)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C13(1.11); C24(1.11)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C13(0.92); C24(0.92)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C13(1.01); C24(1.01)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C13(1.20); C24(1.20)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C13(0.93); C24(0.93)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C13(0.96); C24(0.96)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C13(0.89); C24(0.89)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C13(0.96); C24(0.96)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C13(1.03); C24(1.03)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C13(1.09); C24(1.09)  LDD0681  [2]
 LDCM0365  AC98 HEK-293T C389(1.15); C976(1.15)  LDD0963  [2]
 LDCM0366  AC99 HEK-293T C389(0.46); C976(0.46)  LDD0964  [2]
 LDCM0248  AKOS034007472 HCT 116 C13(1.23); C24(1.23); C389(0.91)  LDD0565  [2]
 LDCM0356  AKOS034007680 HCT 116 C389(0.99); C13(1.55); C24(1.55)  LDD0673  [2]
 LDCM0275  AKOS034007705 HCT 116 C13(1.14); C24(1.14); C389(1.63)  LDD0592  [2]
 LDCM0020  ARS-1620 HCC44 C276(0.95); C282(0.95); C13(0.87); C24(0.87)  LDD0078  [2]
 LDCM0369  CL100 HEK-293T C389(1.11); C976(1.11)  LDD0967  [2]
 LDCM0370  CL101 HCT 116 C389(1.16); C13(1.62); C24(1.62)  LDD0687  [2]
 LDCM0371  CL102 HCT 116 C389(0.88); C13(1.06); C24(1.06)  LDD0688  [2]
 LDCM0372  CL103 HCT 116 C389(0.99); C13(1.26); C24(1.26)  LDD0689  [2]
 LDCM0373  CL104 HCT 116 C389(0.95); C13(1.31); C24(1.31)  LDD0690  [2]
 LDCM0374  CL105 HCT 116 C389(0.81)  LDD0691  [2]
 LDCM0375  CL106 HCT 116 C389(0.81)  LDD0692  [2]
 LDCM0376  CL107 HCT 116 C389(0.82)  LDD0693  [2]
 LDCM0377  CL108 HCT 116 C389(0.81)  LDD0694  [2]
 LDCM0378  CL109 HCT 116 C389(0.85)  LDD0695  [2]
 LDCM0380  CL110 HCT 116 C389(0.69)  LDD0697  [2]
 LDCM0381  CL111 HCT 116 C389(0.73)  LDD0698  [2]
 LDCM0382  CL112 HEK-293T C389(0.95)  LDD1586  [6]
 LDCM0386  CL116 HEK-293T C389(0.87)  LDD1590  [6]
 LDCM0391  CL120 HEK-293T C389(1.03)  LDD1595  [6]
 LDCM0395  CL124 HEK-293T C389(1.06)  LDD1599  [6]
 LDCM0396  CL125 HCT 116 C389(1.14)  LDD0713  [2]
 LDCM0397  CL126 HCT 116 C389(1.04)  LDD0714  [2]
 LDCM0398  CL127 HCT 116 C389(1.22)  LDD0715  [2]
 LDCM0399  CL128 HCT 116 C389(1.12)  LDD0716  [2]
 LDCM0403  CL16 HEK-293T C389(1.03)  LDD1607  [6]
 LDCM0406  CL19 HEK-293T C389(0.97)  LDD1610  [6]
 LDCM0416  CL28 HEK-293T C389(1.06)  LDD1620  [6]
 LDCM0420  CL31 HEK-293T C389(0.69); C976(0.69)  LDD1018  [2]
 LDCM0421  CL32 HEK-293T C389(0.89); C976(0.89)  LDD1019  [2]
 LDCM0422  CL33 HEK-293T C389(0.93); C976(0.93)  LDD1020  [2]
 LDCM0423  CL34 HEK-293T C389(0.68); C976(0.68)  LDD1021  [2]
 LDCM0424  CL35 HEK-293T C389(0.80); C976(0.80)  LDD1022  [2]
 LDCM0425  CL36 HEK-293T C389(0.76); C976(0.76)  LDD1023  [2]
 LDCM0426  CL37 HEK-293T C389(0.87); C976(0.87)  LDD1024  [2]
 LDCM0428  CL39 HEK-293T C389(0.99); C976(0.99)  LDD1026  [2]
 LDCM0429  CL4 HEK-293T C389(0.92)  LDD1633  [6]
 LDCM0430  CL40 HEK-293T C389(0.99); C976(0.99)  LDD1028  [2]
 LDCM0431  CL41 HEK-293T C389(0.88); C976(0.88)  LDD1029  [2]
 LDCM0432  CL42 HEK-293T C389(0.90); C976(0.90)  LDD1030  [2]
 LDCM0433  CL43 HEK-293T C389(0.85); C976(0.85)  LDD1031  [2]
 LDCM0434  CL44 HEK-293T C389(0.77); C976(0.77)  LDD1032  [2]
 LDCM0435  CL45 HEK-293T C389(1.15); C976(1.15)  LDD1033  [2]
 LDCM0436  CL46 HCT 116 C389(1.01)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C389(0.91)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C389(0.85)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C389(0.85)  LDD0756  [2]
 LDCM0441  CL50 HCT 116 C389(0.96)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C389(0.92)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C389(1.06)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C389(1.14)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C389(0.92)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C389(0.93)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C389(0.87)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C389(0.86)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C389(1.06)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C389(0.88)  LDD0767  [2]
 LDCM0452  CL60 HCT 116 C389(0.81)  LDD0769  [2]
 LDCM0453  CL61 HEK-293T C389(0.89); C976(0.89)  LDD1051  [2]
 LDCM0454  CL62 HEK-293T C389(0.85); C976(0.85)  LDD1052  [2]
 LDCM0455  CL63 HEK-293T C389(0.56); C976(0.56)  LDD1053  [2]
 LDCM0456  CL64 HEK-293T C389(0.59); C976(0.59)  LDD1054  [2]
 LDCM0457  CL65 HEK-293T C389(0.67); C976(0.67)  LDD1055  [2]
 LDCM0458  CL66 HEK-293T C389(0.58); C976(0.58)  LDD1056  [2]
 LDCM0459  CL67 HEK-293T C389(0.86); C976(0.86)  LDD1057  [2]
 LDCM0460  CL68 HEK-293T C389(1.01); C976(1.01)  LDD1058  [2]
 LDCM0461  CL69 HEK-293T C389(0.76); C976(0.76)  LDD1059  [2]
 LDCM0462  CL7 HEK-293T C389(0.91)  LDD1665  [6]
 LDCM0463  CL70 HEK-293T C389(1.04); C976(1.04)  LDD1061  [2]
 LDCM0464  CL71 HEK-293T C389(0.86); C976(0.86)  LDD1062  [2]
 LDCM0465  CL72 HEK-293T C389(0.93); C976(0.93)  LDD1063  [2]
 LDCM0466  CL73 HEK-293T C389(1.15); C976(1.15)  LDD1064  [2]
 LDCM0467  CL74 HEK-293T C389(0.89); C976(0.89)  LDD1065  [2]
 LDCM0469  CL76 HCT 116 C389(0.92)  LDD0786  [2]
 LDCM0470  CL77 HCT 116 C389(0.89)  LDD0787  [2]
 LDCM0471  CL78 HCT 116 C389(0.94)  LDD0788  [2]
 LDCM0472  CL79 HCT 116 C389(0.90)  LDD0789  [2]
 LDCM0474  CL80 HCT 116 C389(0.78)  LDD0791  [2]
 LDCM0475  CL81 HCT 116 C389(0.79)  LDD0792  [2]
 LDCM0476  CL82 HCT 116 C389(0.73)  LDD0793  [2]
 LDCM0477  CL83 HCT 116 C389(0.95)  LDD0794  [2]
 LDCM0478  CL84 HCT 116 C389(1.15)  LDD0795  [2]
 LDCM0479  CL85 HCT 116 C389(0.91)  LDD0796  [2]
 LDCM0480  CL86 HCT 116 C389(0.94)  LDD0797  [2]
 LDCM0481  CL87 HCT 116 C389(0.78)  LDD0798  [2]
 LDCM0482  CL88 HCT 116 C389(0.95)  LDD0799  [2]
 LDCM0483  CL89 HCT 116 C389(0.93)  LDD0800  [2]
 LDCM0485  CL90 HCT 116 C389(0.86)  LDD0802  [2]
 LDCM0486  CL91 HEK-293T C389(0.70); C976(0.70)  LDD1084  [2]
 LDCM0487  CL92 HEK-293T C389(0.80); C976(0.80)  LDD1085  [2]
 LDCM0488  CL93 HEK-293T C389(0.74); C976(0.74)  LDD1086  [2]
 LDCM0489  CL94 HEK-293T C389(0.67); C976(0.67)  LDD1087  [2]
 LDCM0490  CL95 HEK-293T C389(0.63); C976(0.63)  LDD1088  [2]
 LDCM0491  CL96 HEK-293T C389(0.79); C976(0.79)  LDD1089  [2]
 LDCM0492  CL97 HEK-293T C389(0.72); C976(0.72)  LDD1090  [2]
 LDCM0493  CL98 HEK-293T C389(0.81); C976(0.81)  LDD1091  [2]
 LDCM0494  CL99 HEK-293T C389(0.91); C976(0.91)  LDD1092  [2]
 LDCM0468  Fragment33 HEK-293T C389(0.63); C976(0.63)  LDD1066  [2]
 LDCM0427  Fragment51 HEK-293T C389(0.91); C976(0.91)  LDD1025  [2]
 LDCM0022  KB02 769-P C389(1.83)  LDD2246  [7]
 LDCM0023  KB03 769-P C389(1.50)  LDD2663  [7]
 LDCM0024  KB05 MKN45 C389(2.41)  LDD3332  [7]
 LDCM0021  THZ1 HCT 116 C13(1.19); C24(1.19)  LDD2173  [2]

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
4 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
5 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
6 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
7 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840