Details of the Target

General Information of Target

Target ID LDTP07889
Target Name Chondroitin sulfate synthase 3 (CHSY3)
Gene Name CHSY3
Gene ID 337876
Synonyms
CHSY2; CSS3; Chondroitin sulfate synthase 3; EC 2.4.1.175; EC 2.4.1.226; Carbohydrate synthase 2; Chondroitin glucuronyltransferase 3; Chondroitin synthase 2; ChSy-2; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3; N-acetylgalactosaminyltransferase 3
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAVRSRRPWMSVALGLVLGFTAASWLIAPRVAELSERKRRGSSLCSYYGRSAAGPRAGAQ
QPLPQPQSRPRQEQSPPPARQDLQGPPLPEAAPGITSFRSSPWQQPPPLQQRRRGREPEG
ATGLPGAPAAEGEPEEEDGGAAGQRRDGRPGSSHNGSGDGGAAAPSARPRDFLYVGVMTA
QKYLGSRALAAQRTWARFIPGRVEFFSSQQPPNAGQPPPPLPVIALPGVDDSYPPQKKSF
MMIKYMHDHYLDKYEWFMRADDDVYIKGDKLEEFLRSLNSSKPLYLGQTGLGNIEELGKL
GLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWS
YEMQQLFHENYEHNRKGYIQDLHNSKIHAAITLHPNKRPAYQYRLHNYMLSRKISELRYR
TIQLHRESALMSKLSNTEVSKEDQQLGVIPSFNHFQPRERNEVIEWEFLTGKLLYSAAEN
QPPRQSLSSILRTALDDTVLQVMEMINENAKSRGRLIDFKEIQYGYRRVNPMHGVEYILD
LLLLYKRHKGRKLTVPVRRHAYLQQLFSKPFFRETEELDVNSLVESINSETQSFSFISNS
LKILSSFQGAKEMGGHNEKKVHILVPLIGRYDIFLRFMENFENMCLIPKQNVKLVIILFS
RDSGQDSSKHIELIKGYQNKYPKAEMTLIPMKGEFSRGLGLEMASAQFDNDTLLLFCDVD
LIFREDFLQRCRDNTIQGQQVYYPIIFSQYDPKVTNGGNPPTDDYFIFSKKTGFWRDYGY
GITCIYKSDLLGAGGFDTSIQGWGLEDVDLYNKVILSGLRPFRSQEVGVVHIFHPVHCDP
NLDPKQYKMCLGSKASTFASTMQLAELWLEKHLGVRYNRTLS
Target Bioclass
Enzyme
Family
Chondroitin N-acetylgalactosaminyltransferase family
Subcellular location
Golgi apparatus, Golgi stack membrane
Function
Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity is much reduced compared to CHSY1.
Uniprot ID
Q70JA7
Ensemble ID
ENST00000305031.5
HGNC ID
HGNC:24293

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C45(0.97)  LDD0547  [1]
IPM
 Probe Info  		N.A.  LDD0025  [2]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [2]
TFBX
 Probe Info  		N.A.  LDD0027  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C45(0.55)  LDD0812  [1]
 LDCM0215  AC10 HEK-293T C45(1.08)  LDD0813  [1]
 LDCM0216  AC100 HEK-293T C45(1.12)  LDD0814  [1]
 LDCM0217  AC101 HEK-293T C45(0.71)  LDD0815  [1]
 LDCM0218  AC102 HEK-293T C45(0.89)  LDD0816  [1]
 LDCM0219  AC103 HEK-293T C45(1.10)  LDD0817  [1]
 LDCM0220  AC104 HEK-293T C45(1.00)  LDD0818  [1]
 LDCM0221  AC105 HEK-293T C45(0.86)  LDD0819  [1]
 LDCM0222  AC106 HEK-293T C45(1.20)  LDD0820  [1]
 LDCM0223  AC107 HEK-293T C45(1.22)  LDD0821  [1]
 LDCM0224  AC108 HEK-293T C45(1.09)  LDD0822  [1]
 LDCM0225  AC109 HEK-293T C45(1.40)  LDD0823  [1]
 LDCM0226  AC11 HEK-293T C45(1.05)  LDD0824  [1]
 LDCM0227  AC110 HEK-293T C45(0.87)  LDD0825  [1]
 LDCM0228  AC111 HEK-293T C45(1.47)  LDD0826  [1]
 LDCM0229  AC112 HEK-293T C45(1.08)  LDD0827  [1]
 LDCM0230  AC113 HCT 116 C45(0.97)  LDD0547  [1]
 LDCM0231  AC114 HCT 116 C45(0.75)  LDD0548  [1]
 LDCM0232  AC115 HCT 116 C45(0.93)  LDD0549  [1]
 LDCM0233  AC116 HCT 116 C45(1.13)  LDD0550  [1]
 LDCM0234  AC117 HCT 116 C45(0.87)  LDD0551  [1]
 LDCM0235  AC118 HCT 116 C45(0.86)  LDD0552  [1]
 LDCM0236  AC119 HCT 116 C45(1.08)  LDD0553  [1]
 LDCM0237  AC12 HEK-293T C45(1.39)  LDD0835  [1]
 LDCM0238  AC120 HCT 116 C45(0.88)  LDD0555  [1]
 LDCM0239  AC121 HCT 116 C45(0.96)  LDD0556  [1]
 LDCM0240  AC122 HCT 116 C45(0.81)  LDD0557  [1]
 LDCM0241  AC123 HCT 116 C45(0.74)  LDD0558  [1]
 LDCM0242  AC124 HCT 116 C45(0.85)  LDD0559  [1]
 LDCM0243  AC125 HCT 116 C45(0.87)  LDD0560  [1]
 LDCM0244  AC126 HCT 116 C45(0.86)  LDD0561  [1]
 LDCM0245  AC127 HCT 116 C45(0.85)  LDD0562  [1]
 LDCM0259  AC14 HEK-293T C45(0.91)  LDD0857  [1]
 LDCM0263  AC143 HEK-293T C45(0.68)  LDD0861  [1]
 LDCM0264  AC144 HEK-293T C45(1.18)  LDD0862  [1]
 LDCM0265  AC145 HEK-293T C45(0.58)  LDD0863  [1]
 LDCM0266  AC146 HEK-293T C45(0.70)  LDD0864  [1]
 LDCM0267  AC147 HEK-293T C45(0.50)  LDD0865  [1]
 LDCM0268  AC148 HEK-293T C45(0.42)  LDD0866  [1]
 LDCM0269  AC149 HEK-293T C45(0.59)  LDD0867  [1]
 LDCM0270  AC15 HEK-293T C45(0.99)  LDD0868  [1]
 LDCM0271  AC150 HEK-293T C45(0.48)  LDD0869  [1]
 LDCM0272  AC151 HEK-293T C45(0.32)  LDD0870  [1]
 LDCM0273  AC152 HEK-293T C45(0.62)  LDD0871  [1]
 LDCM0274  AC153 HEK-293T C45(0.90)  LDD0872  [1]
 LDCM0621  AC154 HEK-293T C45(0.71)  LDD2162  [1]
 LDCM0622  AC155 HEK-293T C45(0.64)  LDD2163  [1]
 LDCM0623  AC156 HEK-293T C45(0.66)  LDD2164  [1]
 LDCM0624  AC157 HEK-293T C45(0.69)  LDD2165  [1]
 LDCM0276  AC17 HCT 116 C45(0.90)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C45(0.77)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C45(0.62)  LDD0595  [1]
 LDCM0279  AC2 HEK-293T C45(0.82)  LDD0877  [1]
 LDCM0280  AC20 HCT 116 C45(0.83)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C45(0.67)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C45(0.68)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C45(0.77)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C45(0.67)  LDD0601  [1]
 LDCM0285  AC25 HCT 116 C45(1.94)  LDD0602  [1]
 LDCM0286  AC26 HCT 116 C45(1.43)  LDD0603  [1]
 LDCM0287  AC27 HCT 116 C45(1.20)  LDD0604  [1]
 LDCM0288  AC28 HCT 116 C45(3.26)  LDD0605  [1]
 LDCM0289  AC29 HCT 116 C45(1.78)  LDD0606  [1]
 LDCM0290  AC3 HEK-293T C45(0.70)  LDD0888  [1]
 LDCM0291  AC30 HCT 116 C45(1.73)  LDD0608  [1]
 LDCM0292  AC31 HCT 116 C45(1.29)  LDD0609  [1]
 LDCM0293  AC32 HCT 116 C45(1.91)  LDD0610  [1]
 LDCM0294  AC33 HCT 116 C45(1.12)  LDD0611  [1]
 LDCM0295  AC34 HCT 116 C45(0.63)  LDD0612  [1]
 LDCM0296  AC35 HEK-293T C309(1.33)  LDD1535  [3]
 LDCM0297  AC36 HEK-293T C645(0.99); C309(0.81)  LDD1536  [3]
 LDCM0299  AC38 HEK-293T C645(0.90)  LDD1538  [3]
 LDCM0300  AC39 HEK-293T C645(1.10); C309(1.05)  LDD1539  [3]
 LDCM0301  AC4 HEK-293T C45(0.68)  LDD0899  [1]
 LDCM0304  AC42 HEK-293T C309(0.79)  LDD1543  [3]
 LDCM0305  AC43 HEK-293T C309(1.02)  LDD1544  [3]
 LDCM0306  AC44 HEK-293T C645(0.72); C309(0.84)  LDD1545  [3]
 LDCM0308  AC46 HEK-293T C645(1.01)  LDD1547  [3]
 LDCM0309  AC47 HEK-293T C645(0.88); C309(1.25)  LDD1548  [3]
 LDCM0312  AC5 HEK-293T C45(0.74)  LDD0910  [1]
 LDCM0313  AC50 HEK-293T C309(0.83)  LDD1552  [3]
 LDCM0314  AC51 HEK-293T C309(1.23)  LDD1553  [3]
 LDCM0315  AC52 HEK-293T C645(0.86); C309(0.87)  LDD1554  [3]
 LDCM0317  AC54 HEK-293T C645(1.16)  LDD1556  [3]
 LDCM0318  AC55 HEK-293T C645(1.05); C309(1.01)  LDD1557  [3]
 LDCM0320  AC57 HEK-293T C45(0.66)  LDD0918  [1]
 LDCM0321  AC58 HEK-293T C45(0.75)  LDD0919  [1]
 LDCM0322  AC59 HEK-293T C45(0.93)  LDD0920  [1]
 LDCM0323  AC6 HEK-293T C45(1.29)  LDD0921  [1]
 LDCM0324  AC60 HEK-293T C45(0.86)  LDD0922  [1]
 LDCM0325  AC61 HEK-293T C45(0.80)  LDD0923  [1]
 LDCM0326  AC62 HEK-293T C45(0.90)  LDD0924  [1]
 LDCM0327  AC63 HEK-293T C45(0.72)  LDD0925  [1]
 LDCM0328  AC64 HEK-293T C45(0.68)  LDD0926  [1]
 LDCM0329  AC65 HEK-293T C45(0.73)  LDD0927  [1]
 LDCM0330  AC66 HEK-293T C45(0.90)  LDD0928  [1]
 LDCM0331  AC67 HEK-293T C45(0.86)  LDD0929  [1]
 LDCM0332  AC68 HCT 116 C45(1.05)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C45(0.88)  LDD0650  [1]
 LDCM0334  AC7 HEK-293T C45(0.87)  LDD0932  [1]
 LDCM0335  AC70 HCT 116 C45(1.14)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C45(0.67)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C45(0.72)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C45(1.00)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C45(1.21)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C45(0.91)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C45(0.55)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C45(1.12)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C45(1.27)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C45(0.98)  LDD0661  [1]
 LDCM0345  AC8 HEK-293T C45(0.83)  LDD0943  [1]
 LDCM0346  AC80 HCT 116 C45(0.57)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C45(1.10)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C45(0.68)  LDD0665  [1]
 LDCM0349  AC83 HEK-293T C45(1.32)  LDD0947  [1]
 LDCM0350  AC84 HEK-293T C45(1.19)  LDD0948  [1]
 LDCM0351  AC85 HEK-293T C45(1.19)  LDD0949  [1]
 LDCM0352  AC86 HEK-293T C45(1.11)  LDD0950  [1]
 LDCM0353  AC87 HEK-293T C45(0.98)  LDD0951  [1]
 LDCM0354  AC88 HEK-293T C45(0.85)  LDD0952  [1]
 LDCM0355  AC89 HEK-293T C45(1.11)  LDD0953  [1]
 LDCM0357  AC90 HEK-293T C45(1.10)  LDD0955  [1]
 LDCM0358  AC91 HEK-293T C45(1.09)  LDD0956  [1]
 LDCM0359  AC92 HEK-293T C45(1.39)  LDD0957  [1]
 LDCM0360  AC93 HEK-293T C45(1.19)  LDD0958  [1]
 LDCM0361  AC94 HEK-293T C45(1.21)  LDD0959  [1]
 LDCM0362  AC95 HEK-293T C45(1.19)  LDD0960  [1]
 LDCM0363  AC96 HEK-293T C45(1.07)  LDD0961  [1]
 LDCM0364  AC97 HEK-293T C45(0.95)  LDD0962  [1]
 LDCM0365  AC98 HEK-293T C45(1.00)  LDD0963  [1]
 LDCM0366  AC99 HEK-293T C45(1.17)  LDD0964  [1]
 LDCM0248  AKOS034007472 HEK-293T C45(0.96)  LDD0846  [1]
 LDCM0356  AKOS034007680 HEK-293T C45(0.99)  LDD0954  [1]
 LDCM0275  AKOS034007705 HEK-293T C45(1.19)  LDD0873  [1]
 LDCM0368  CL10 HEK-293T C645(1.32)  LDD1572  [3]
 LDCM0369  CL100 HEK-293T C45(0.51)  LDD0967  [1]
 LDCM0370  CL101 HEK-293T C45(1.13)  LDD0968  [1]
 LDCM0371  CL102 HEK-293T C45(1.70)  LDD0969  [1]
 LDCM0372  CL103 HEK-293T C45(0.76)  LDD0970  [1]
 LDCM0373  CL104 HEK-293T C45(0.79)  LDD0971  [1]
 LDCM0374  CL105 HCT 116 C45(0.95)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C45(0.56)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C45(0.75)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C45(0.69)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C45(0.85)  LDD0695  [1]
 LDCM0379  CL11 HEK-293T C645(1.10); C309(1.23)  LDD1583  [3]
 LDCM0380  CL110 HCT 116 C45(0.78)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C45(0.51)  LDD0698  [1]
 LDCM0382  CL112 HCT 116 C45(1.12)  LDD0699  [1]
 LDCM0383  CL113 HCT 116 C45(0.90)  LDD0700  [1]
 LDCM0384  CL114 HCT 116 C45(0.76)  LDD0701  [1]
 LDCM0385  CL115 HCT 116 C45(1.03)  LDD0702  [1]
 LDCM0386  CL116 HCT 116 C45(0.88)  LDD0703  [1]
 LDCM0388  CL118 HEK-293T C309(1.36)  LDD1592  [3]
 LDCM0391  CL120 HEK-293T C645(0.82); C309(0.93)  LDD1595  [3]
 LDCM0393  CL122 HEK-293T C309(1.27)  LDD1597  [3]
 LDCM0395  CL124 HEK-293T C645(0.80); C309(0.83)  LDD1599  [3]
 LDCM0396  CL125 HEK-293T C45(0.74)  LDD0994  [1]
 LDCM0397  CL126 HEK-293T C45(0.57)  LDD0995  [1]
 LDCM0398  CL127 HEK-293T C45(0.70)  LDD0996  [1]
 LDCM0399  CL128 HEK-293T C45(0.72)  LDD0997  [1]
 LDCM0401  CL14 HEK-293T C309(1.18)  LDD1605  [3]
 LDCM0403  CL16 HEK-293T C645(0.73); C309(1.14)  LDD1607  [3]
 LDCM0405  CL18 HEK-293T C309(0.84)  LDD1609  [3]
 LDCM0406  CL19 HEK-293T C309(1.01)  LDD1610  [3]
 LDCM0407  CL2 HEK-293T C309(1.02)  LDD1611  [3]
 LDCM0408  CL20 HEK-293T C645(1.00); C309(0.91)  LDD1612  [3]
 LDCM0410  CL22 HEK-293T C645(1.11)  LDD1614  [3]
 LDCM0411  CL23 HEK-293T C645(0.99); C309(0.92)  LDD1615  [3]
 LDCM0414  CL26 HEK-293T C309(1.33)  LDD1618  [3]
 LDCM0416  CL28 HEK-293T C645(0.53); C309(1.26)  LDD1620  [3]
 LDCM0419  CL30 HEK-293T C309(0.78)  LDD1623  [3]
 LDCM0420  CL31 HEK-293T C309(0.98)  LDD1624  [3]
 LDCM0421  CL32 HEK-293T C645(0.85); C309(0.78)  LDD1625  [3]
 LDCM0423  CL34 HEK-293T C645(1.12)  LDD1627  [3]
 LDCM0424  CL35 HEK-293T C645(1.12); C309(1.00)  LDD1628  [3]
 LDCM0429  CL4 HEK-293T C645(0.90); C309(0.81)  LDD1633  [3]
 LDCM0430  CL40 HEK-293T C645(0.97); C309(0.89)  LDD1634  [3]
 LDCM0432  CL42 HEK-293T C309(0.70)  LDD1636  [3]
 LDCM0433  CL43 HEK-293T C309(1.03)  LDD1637  [3]
 LDCM0434  CL44 HEK-293T C645(0.81); C309(0.86)  LDD1638  [3]
 LDCM0436  CL46 HCT 116 C45(1.18)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C45(1.54)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C45(2.05)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C45(1.46)  LDD0756  [1]
 LDCM0441  CL50 HCT 116 C45(1.55)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C45(1.26)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C45(1.38)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C45(1.29)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C45(1.25)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C45(1.22)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C45(1.37)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C45(1.54)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C45(1.03)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C45(1.22)  LDD0767  [1]
 LDCM0451  CL6 HEK-293T C309(0.93)  LDD1654  [3]
 LDCM0452  CL60 HCT 116 C45(2.06)  LDD0769  [1]
 LDCM0453  CL61 HEK-293T C45(0.60)  LDD1051  [1]
 LDCM0454  CL62 HEK-293T C45(0.87)  LDD1052  [1]
 LDCM0455  CL63 HEK-293T C45(0.61)  LDD1053  [1]
 LDCM0456  CL64 HEK-293T C45(0.67)  LDD1054  [1]
 LDCM0457  CL65 HEK-293T C45(0.67)  LDD1055  [1]
 LDCM0458  CL66 HEK-293T C45(0.52)  LDD1056  [1]
 LDCM0459  CL67 HEK-293T C45(0.49)  LDD1057  [1]
 LDCM0460  CL68 HEK-293T C45(0.65)  LDD1058  [1]
 LDCM0461  CL69 HEK-293T C45(0.56)  LDD1059  [1]
 LDCM0462  CL7 HEK-293T C309(1.11)  LDD1665  [3]
 LDCM0463  CL70 HEK-293T C45(0.59)  LDD1061  [1]
 LDCM0464  CL71 HEK-293T C45(0.75)  LDD1062  [1]
 LDCM0465  CL72 HEK-293T C45(0.90)  LDD1063  [1]
 LDCM0466  CL73 HEK-293T C45(0.81)  LDD1064  [1]
 LDCM0467  CL74 HEK-293T C45(1.00)  LDD1065  [1]
 LDCM0469  CL76 HEK-293T C45(0.67)  LDD1067  [1]
 LDCM0470  CL77 HEK-293T C45(0.46)  LDD1068  [1]
 LDCM0471  CL78 HEK-293T C45(0.84)  LDD1069  [1]
 LDCM0472  CL79 HEK-293T C45(0.65)  LDD1070  [1]
 LDCM0473  CL8 HEK-293T C645(0.94); C309(0.82)  LDD1676  [3]
 LDCM0474  CL80 HEK-293T C45(0.65)  LDD1072  [1]
 LDCM0475  CL81 HEK-293T C45(0.64)  LDD1073  [1]
 LDCM0476  CL82 HEK-293T C45(0.56)  LDD1074  [1]
 LDCM0477  CL83 HEK-293T C45(0.57)  LDD1075  [1]
 LDCM0478  CL84 HEK-293T C45(0.80)  LDD1076  [1]
 LDCM0479  CL85 HEK-293T C45(0.72)  LDD1077  [1]
 LDCM0480  CL86 HEK-293T C45(0.65)  LDD1078  [1]
 LDCM0481  CL87 HEK-293T C45(0.99)  LDD1079  [1]
 LDCM0482  CL88 HEK-293T C45(1.25)  LDD1080  [1]
 LDCM0483  CL89 HEK-293T C45(0.70)  LDD1081  [1]
 LDCM0485  CL90 HEK-293T C45(0.46)  LDD1083  [1]
 LDCM0486  CL91 HEK-293T C45(0.62)  LDD1084  [1]
 LDCM0487  CL92 HEK-293T C45(0.50)  LDD1085  [1]
 LDCM0488  CL93 HEK-293T C45(0.68)  LDD1086  [1]
 LDCM0489  CL94 HEK-293T C45(0.61)  LDD1087  [1]
 LDCM0490  CL95 HEK-293T C45(1.12)  LDD1088  [1]
 LDCM0491  CL96 HEK-293T C45(0.43)  LDD1089  [1]
 LDCM0492  CL97 HEK-293T C45(0.51)  LDD1090  [1]
 LDCM0493  CL98 HEK-293T C45(0.40)  LDD1091  [1]
 LDCM0494  CL99 HEK-293T C45(0.72)  LDD1092  [1]
 LDCM0468  Fragment33 HEK-293T C45(0.76)  LDD1066  [1]
 LDCM0427  Fragment51 HEK-293T C309(1.28)  LDD1631  [3]
 LDCM0022  KB02 COLO-679 C309(3.02)  LDD2305  [4]
 LDCM0023  KB03 A2058 C309(1.34)  LDD2670  [4]
 LDCM0024  KB05 A2058 C309(1.17)  LDD3087  [4]

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
3 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
4 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840