General Information of Experiment

Probe Name C395  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 8 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01769  Dihydrofolate reductase (DHFR) 16.8
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 11.2
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 9.7
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 8.2
 LDTP10699  E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) 7.2
 LDTP09088  Phospholipase A2 group XV (PLA2G15) 7.0
 LDTP10032  7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) 6.0
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 4.9
Transporter and channel
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 7.6
Other
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01075  Protein CutA (CUTA) 10.9
 LDTP15067  Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) 7.3
 LDTP05160  Nucleobindin-2 (NUCB2) 6.1

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587