Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C335  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 9 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP05128  Glutathione S-transferase omega-1 (GSTO1) 14.2
 LDTP06227  Prostaglandin reductase 1 (PTGR1) 13.4
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 10.3
 LDTP00624  Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT2) 9.0
 LDTP10032  7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) 8.5
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 8.1
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 7.8
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 7.7
 LDTP00988  Protein O-GlcNAcase (OGA) 6.1
Transporter and channel
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP16069  Peroxisomal membrane protein 2 (PXMP2) 17.3
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 6.7
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 5.0
Other
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 14.5
 LDTP15623  Neuferricin (CYB5D2) 6.1

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587