Details of the Target

General Information of Target

Target ID LDTP18118
Target Name Putative deoxyribonuclease TATDN2 (TATDN2)
Gene Name TATDN2
Gene ID 9797
Synonyms
KIAA0218; Putative deoxyribonuclease TATDN2; EC 3.1.21.-
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MIMRELKADACLNSHMGAMWETNRSVKENSSQSKKYSTQIECLSPGSACRHFRSFHYHEA
TEPLEAINQLQKLCHQWLRPEIHSKKHILEMLVLEHFLTILPKGTQNWVQKHHPQLAKQA
LVLVERLQREPGGTKNEVTAHELGEEAVLLRGTTVAPGFKWKPAELEPMERILEHIQILA
LSEHKSTKDWKMAPKLIWPESQSLLTFEDMAVYFSEEEWQLLGPLEKTLYNDVMQDIYET
AISLGKQRTGKIMGIEMASSFSKEEKKLTTCKQELPKLMDLHGKGHTGEKPFKCQDCGKI
FRVSSDLIKHQRIHTEEKLYKCQQCDRRFRWSSGLNKHFMTHQGINPYRCSWYGKSISYD
TNLQTHQRIHTGEKPFKCHECGKIFIHKSNLIKYQRTHTGEQPYTCSICRRNFSRQLSLL
RHQKLH
Target Bioclass
Enzyme
Family
Metallo-dependent hydrolases superfamily, TatD-type hydrolase family
Subcellular location
Nucleus
Function Putative deoxyribonuclease.
Uniprot ID
Q93075
Ensemble ID
ENST00000287652.8
HGNC ID
HGNC:28988

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 7 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		12.01  LDD0403  [1]
DBIA
 Probe Info  		C546(1.95)  LDD3337  [2]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [3]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [4]
IPM
 Probe Info  		N.A.  LDD2156  [5]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [6]
AOyne
 Probe Info  		15.00  LDD0443  [7]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C631(0.99)  LDD0812  [8]
 LDCM0215  AC10 HEK-293T C631(1.12)  LDD0813  [8]
 LDCM0216  AC100 HEK-293T C602(1.25); C631(1.28)  LDD0814  [8]
 LDCM0217  AC101 HEK-293T C602(1.20); C631(1.26)  LDD0815  [8]
 LDCM0218  AC102 HEK-293T C602(1.28); C631(1.46)  LDD0816  [8]
 LDCM0219  AC103 HEK-293T C602(1.48); C631(1.10)  LDD0817  [8]
 LDCM0220  AC104 HEK-293T C602(1.30); C631(1.20)  LDD0818  [8]
 LDCM0221  AC105 HEK-293T C602(1.77); C631(1.26)  LDD0819  [8]
 LDCM0222  AC106 HEK-293T C602(1.37); C631(1.06)  LDD0820  [8]
 LDCM0223  AC107 HEK-293T C602(1.13); C631(1.00)  LDD0821  [8]
 LDCM0224  AC108 HEK-293T C602(1.19); C631(1.10)  LDD0822  [8]
 LDCM0225  AC109 HEK-293T C602(1.41); C631(0.89)  LDD0823  [8]
 LDCM0226  AC11 HEK-293T C631(1.17)  LDD0824  [8]
 LDCM0227  AC110 HEK-293T C602(1.57); C631(1.76)  LDD0825  [8]
 LDCM0228  AC111 HEK-293T C602(2.12); C631(2.41)  LDD0826  [8]
 LDCM0229  AC112 HEK-293T C602(1.95); C631(2.75)  LDD0827  [8]
 LDCM0230  AC113 HEK-293T C602(1.13); C631(1.04)  LDD0828  [8]
 LDCM0231  AC114 HEK-293T C602(1.25); C631(1.08)  LDD0829  [8]
 LDCM0232  AC115 HEK-293T C602(0.92); C631(1.02)  LDD0830  [8]
 LDCM0233  AC116 HEK-293T C602(1.43); C631(1.37)  LDD0831  [8]
 LDCM0234  AC117 HEK-293T C602(1.29); C631(1.25)  LDD0832  [8]
 LDCM0235  AC118 HEK-293T C602(1.26); C631(1.30)  LDD0833  [8]
 LDCM0236  AC119 HEK-293T C602(1.14); C631(1.56)  LDD0834  [8]
 LDCM0237  AC12 HEK-293T C631(1.33)  LDD0835  [8]
 LDCM0238  AC120 HEK-293T C602(1.02); C631(1.24)  LDD0836  [8]
 LDCM0239  AC121 HEK-293T C602(1.43); C631(1.34)  LDD0837  [8]
 LDCM0240  AC122 HEK-293T C602(1.49); C631(1.52)  LDD0838  [8]
 LDCM0241  AC123 HEK-293T C602(1.34); C631(1.51)  LDD0839  [8]
 LDCM0242  AC124 HEK-293T C602(1.22); C631(1.45)  LDD0840  [8]
 LDCM0243  AC125 HEK-293T C602(1.56); C631(1.61)  LDD0841  [8]
 LDCM0244  AC126 HEK-293T C602(1.72); C631(2.08)  LDD0842  [8]
 LDCM0245  AC127 HEK-293T C602(2.22); C631(2.28)  LDD0843  [8]
 LDCM0246  AC128 PaTu 8988t C631(0.80)  LDD1125  [8]
 LDCM0247  AC129 PaTu 8988t C631(0.77)  LDD1126  [8]
 LDCM0249  AC130 PaTu 8988t C631(0.74)  LDD1128  [8]
 LDCM0250  AC131 PaTu 8988t C631(0.85)  LDD1129  [8]
 LDCM0251  AC132 PaTu 8988t C631(0.99)  LDD1130  [8]
 LDCM0252  AC133 PaTu 8988t C631(0.94)  LDD1131  [8]
 LDCM0253  AC134 PaTu 8988t C631(0.98)  LDD1132  [8]
 LDCM0254  AC135 PaTu 8988t C631(0.84)  LDD1133  [8]
 LDCM0255  AC136 PaTu 8988t C631(0.82)  LDD1134  [8]
 LDCM0256  AC137 PaTu 8988t C631(0.79)  LDD1135  [8]
 LDCM0257  AC138 PaTu 8988t C631(0.94)  LDD1136  [8]
 LDCM0258  AC139 PaTu 8988t C631(0.86)  LDD1137  [8]
 LDCM0259  AC14 HEK-293T C631(1.10)  LDD0857  [8]
 LDCM0260  AC140 PaTu 8988t C631(0.86)  LDD1139  [8]
 LDCM0261  AC141 PaTu 8988t C631(0.95)  LDD1140  [8]
 LDCM0262  AC142 PaTu 8988t C631(0.78)  LDD1141  [8]
 LDCM0263  AC143 HEK-293T C602(1.13); C631(1.53)  LDD0861  [8]
 LDCM0264  AC144 HEK-293T C602(1.26); C631(1.68)  LDD0862  [8]
 LDCM0265  AC145 HEK-293T C602(1.17); C631(1.42)  LDD0863  [8]
 LDCM0266  AC146 HEK-293T C602(1.21); C631(1.32)  LDD0864  [8]
 LDCM0267  AC147 HEK-293T C602(1.49); C631(1.30)  LDD0865  [8]
 LDCM0268  AC148 HEK-293T C602(1.45); C631(0.89)  LDD0866  [8]
 LDCM0269  AC149 HEK-293T C602(0.95); C631(1.04)  LDD0867  [8]
 LDCM0270  AC15 HEK-293T C631(1.42)  LDD0868  [8]
 LDCM0271  AC150 HEK-293T C602(1.09); C631(1.22)  LDD0869  [8]
 LDCM0272  AC151 HEK-293T C602(1.18); C631(1.04)  LDD0870  [8]
 LDCM0273  AC152 HEK-293T C602(1.11); C631(1.29)  LDD0871  [8]
 LDCM0274  AC153 HEK-293T C602(1.13); C631(0.95)  LDD0872  [8]
 LDCM0621  AC154 HEK-293T C602(1.11); C631(1.18)  LDD2162  [8]
 LDCM0622  AC155 HEK-293T C602(1.05); C631(1.42)  LDD2163  [8]
 LDCM0623  AC156 HEK-293T C602(1.44); C631(2.20)  LDD2164  [8]
 LDCM0624  AC157 HEK-293T C602(1.59); C631(1.87)  LDD2165  [8]
 LDCM0276  AC17 HEK-293T C631(1.52)  LDD0874  [8]
 LDCM0277  AC18 HEK-293T C631(1.27)  LDD0875  [8]
 LDCM0278  AC19 HEK-293T C631(1.27)  LDD0876  [8]
 LDCM0279  AC2 HEK-293T C631(1.13)  LDD0877  [8]
 LDCM0280  AC20 HEK-293T C631(1.51)  LDD0878  [8]
 LDCM0281  AC21 HEK-293T C631(1.43)  LDD0879  [8]
 LDCM0282  AC22 HEK-293T C631(1.50)  LDD0880  [8]
 LDCM0283  AC23 HEK-293T C631(1.71)  LDD0881  [8]
 LDCM0284  AC24 HEK-293T C631(1.28)  LDD0882  [8]
 LDCM0285  AC25 HEK-293T C602(1.03); C631(1.65)  LDD0883  [8]
 LDCM0286  AC26 HEK-293T C602(0.98); C631(1.47)  LDD0884  [8]
 LDCM0287  AC27 HEK-293T C602(1.00); C631(1.46)  LDD0885  [8]
 LDCM0288  AC28 HEK-293T C602(1.13); C631(1.13)  LDD0886  [8]
 LDCM0289  AC29 HEK-293T C602(1.21); C631(1.51)  LDD0887  [8]
 LDCM0290  AC3 HEK-293T C631(0.99)  LDD0888  [8]
 LDCM0291  AC30 HEK-293T C602(1.27); C631(1.24)  LDD0889  [8]
 LDCM0292  AC31 HEK-293T C602(0.86); C631(1.24)  LDD0890  [8]
 LDCM0293  AC32 HEK-293T C602(1.11); C631(1.06)  LDD0891  [8]
 LDCM0294  AC33 HEK-293T C602(1.22); C631(1.67)  LDD0892  [8]
 LDCM0295  AC34 HEK-293T C602(1.12); C631(1.45)  LDD0893  [8]
 LDCM0296  AC35 HEK-293T C602(1.22)  LDD0894  [8]
 LDCM0297  AC36 HEK-293T C602(1.69)  LDD0895  [8]
 LDCM0298  AC37 HEK-293T C602(2.13)  LDD0896  [8]
 LDCM0299  AC38 HEK-293T C602(1.29)  LDD0897  [8]
 LDCM0300  AC39 HEK-293T C602(1.58)  LDD0898  [8]
 LDCM0301  AC4 HEK-293T C631(0.99)  LDD0899  [8]
 LDCM0302  AC40 HEK-293T C602(2.06)  LDD0900  [8]
 LDCM0303  AC41 HEK-293T C602(1.61)  LDD0901  [8]
 LDCM0304  AC42 HEK-293T C602(1.74)  LDD0902  [8]
 LDCM0305  AC43 HEK-293T C602(1.41)  LDD0903  [8]
 LDCM0306  AC44 HEK-293T C602(1.62)  LDD0904  [8]
 LDCM0307  AC45 HEK-293T C602(1.42)  LDD0905  [8]
 LDCM0308  AC46 HEK-293T C602(1.23); C631(1.11)  LDD0906  [8]
 LDCM0309  AC47 HEK-293T C602(1.44); C631(1.26)  LDD0907  [8]
 LDCM0310  AC48 HEK-293T C602(1.17); C631(1.85)  LDD0908  [8]
 LDCM0311  AC49 HEK-293T C602(1.09); C631(1.50)  LDD0909  [8]
 LDCM0312  AC5 HEK-293T C631(1.21)  LDD0910  [8]
 LDCM0313  AC50 HEK-293T C602(1.00); C631(1.24)  LDD0911  [8]
 LDCM0314  AC51 HEK-293T C602(1.43); C631(1.41)  LDD0912  [8]
 LDCM0315  AC52 HEK-293T C602(1.54); C631(1.86)  LDD0913  [8]
 LDCM0316  AC53 HEK-293T C602(1.25); C631(1.41)  LDD0914  [8]
 LDCM0317  AC54 HEK-293T C602(1.32); C631(1.46)  LDD0915  [8]
 LDCM0318  AC55 HEK-293T C602(1.39); C631(1.38)  LDD0916  [8]
 LDCM0319  AC56 HEK-293T C602(1.25); C631(1.39)  LDD0917  [8]
 LDCM0320  AC57 HEK-293T C602(1.12)  LDD0918  [8]
 LDCM0321  AC58 HEK-293T C602(1.35)  LDD0919  [8]
 LDCM0322  AC59 HEK-293T C602(1.22)  LDD0920  [8]
 LDCM0323  AC6 HEK-293T C631(1.08)  LDD0921  [8]
 LDCM0324  AC60 HEK-293T C602(3.08)  LDD0922  [8]
 LDCM0325  AC61 HEK-293T C602(1.69)  LDD0923  [8]
 LDCM0326  AC62 HEK-293T C602(1.49)  LDD0924  [8]
 LDCM0327  AC63 HEK-293T C602(1.45)  LDD0925  [8]
 LDCM0328  AC64 HEK-293T C602(1.13)  LDD0926  [8]
 LDCM0329  AC65 HEK-293T C602(1.69)  LDD0927  [8]
 LDCM0330  AC66 HEK-293T C602(1.22)  LDD0928  [8]
 LDCM0331  AC67 HEK-293T C602(1.39)  LDD0929  [8]
 LDCM0334  AC7 HEK-293T C631(1.20)  LDD0932  [8]
 LDCM0345  AC8 HEK-293T C631(1.51)  LDD0943  [8]
 LDCM0349  AC83 HEK-293T C631(0.93)  LDD0947  [8]
 LDCM0350  AC84 HEK-293T C631(1.32)  LDD0948  [8]
 LDCM0351  AC85 HEK-293T C631(1.72)  LDD0949  [8]
 LDCM0352  AC86 HEK-293T C631(1.06)  LDD0950  [8]
 LDCM0353  AC87 HEK-293T C631(1.53)  LDD0951  [8]
 LDCM0354  AC88 HEK-293T C631(1.36)  LDD0952  [8]
 LDCM0355  AC89 HEK-293T C631(1.06)  LDD0953  [8]
 LDCM0357  AC90 HEK-293T C631(1.59)  LDD0955  [8]
 LDCM0358  AC91 HEK-293T C631(1.41)  LDD0956  [8]
 LDCM0359  AC92 HEK-293T C631(1.09)  LDD0957  [8]
 LDCM0360  AC93 HEK-293T C631(1.46)  LDD0958  [8]
 LDCM0361  AC94 HEK-293T C631(1.32)  LDD0959  [8]
 LDCM0362  AC95 HEK-293T C631(1.39)  LDD0960  [8]
 LDCM0363  AC96 HEK-293T C631(1.23)  LDD0961  [8]
 LDCM0364  AC97 HEK-293T C631(2.48)  LDD0962  [8]
 LDCM0365  AC98 HEK-293T C602(1.13); C631(1.01)  LDD0963  [8]
 LDCM0366  AC99 HEK-293T C602(0.99); C631(1.11)  LDD0964  [8]
 LDCM0248  AKOS034007472 HEK-293T C631(1.13)  LDD0846  [8]
 LDCM0356  AKOS034007680 HEK-293T C631(1.52)  LDD0954  [8]
 LDCM0275  AKOS034007705 HEK-293T C631(1.35)  LDD0873  [8]
 LDCM0156  Aniline NCI-H1299 12.01  LDD0403  [1]
 LDCM0367  CL1 HEK-293T C602(1.11); C631(1.07)  LDD0965  [8]
 LDCM0368  CL10 HEK-293T C602(1.82); C631(2.28)  LDD0966  [8]
 LDCM0369  CL100 HEK-293T C631(1.23)  LDD0967  [8]
 LDCM0370  CL101 HEK-293T C631(1.33)  LDD0968  [8]
 LDCM0371  CL102 HEK-293T C631(1.59)  LDD0969  [8]
 LDCM0372  CL103 HEK-293T C631(1.27)  LDD0970  [8]
 LDCM0373  CL104 HEK-293T C631(1.43)  LDD0971  [8]
 LDCM0374  CL105 HEK-293T C631(1.25)  LDD0972  [8]
 LDCM0375  CL106 HEK-293T C631(1.23)  LDD0973  [8]
 LDCM0376  CL107 HEK-293T C631(1.28)  LDD0974  [8]
 LDCM0377  CL108 HEK-293T C631(1.19)  LDD0975  [8]
 LDCM0378  CL109 HEK-293T C631(1.19)  LDD0976  [8]
 LDCM0379  CL11 HEK-293T C602(1.75); C631(2.23)  LDD0977  [8]
 LDCM0380  CL110 HEK-293T C631(1.33)  LDD0978  [8]
 LDCM0381  CL111 HEK-293T C631(1.26)  LDD0979  [8]
 LDCM0382  CL112 HEK-293T C602(0.99); C631(1.42)  LDD0980  [8]
 LDCM0383  CL113 HEK-293T C602(0.88); C631(1.21)  LDD0981  [8]
 LDCM0384  CL114 HEK-293T C602(1.50); C631(2.23)  LDD0982  [8]
 LDCM0385  CL115 HEK-293T C602(1.11); C631(1.82)  LDD0983  [8]
 LDCM0386  CL116 HEK-293T C602(1.11); C631(1.51)  LDD0984  [8]
 LDCM0387  CL117 HEK-293T C602(1.57)  LDD0985  [8]
 LDCM0388  CL118 HEK-293T C602(1.22)  LDD0986  [8]
 LDCM0389  CL119 HEK-293T C602(1.44)  LDD0987  [8]
 LDCM0390  CL12 HEK-293T C602(1.25); C631(1.29)  LDD0988  [8]
 LDCM0391  CL120 HEK-293T C602(2.05)  LDD0989  [8]
 LDCM0392  CL121 HEK-293T C602(1.23); C631(1.29)  LDD0990  [8]
 LDCM0393  CL122 HEK-293T C602(1.22); C631(1.34)  LDD0991  [8]
 LDCM0394  CL123 HEK-293T C602(1.09); C631(1.12)  LDD0992  [8]
 LDCM0395  CL124 HEK-293T C602(1.26); C631(1.48)  LDD0993  [8]
 LDCM0396  CL125 HEK-293T C602(1.13)  LDD0994  [8]
 LDCM0397  CL126 HEK-293T C602(1.21)  LDD0995  [8]
 LDCM0398  CL127 HEK-293T C602(1.02)  LDD0996  [8]
 LDCM0399  CL128 HEK-293T C602(1.28)  LDD0997  [8]
 LDCM0400  CL13 HEK-293T C602(1.32); C631(1.25)  LDD0998  [8]
 LDCM0401  CL14 HEK-293T C602(1.35); C631(1.39)  LDD0999  [8]
 LDCM0402  CL15 HEK-293T C602(1.88); C631(1.64)  LDD1000  [8]
 LDCM0403  CL16 HEK-293T C602(0.78); C631(1.12)  LDD1001  [8]
 LDCM0404  CL17 HEK-293T C602(0.85); C631(1.12)  LDD1002  [8]
 LDCM0405  CL18 HEK-293T C602(0.86); C631(1.22)  LDD1003  [8]
 LDCM0406  CL19 HEK-293T C602(1.05); C631(1.11)  LDD1004  [8]
 LDCM0407  CL2 HEK-293T C602(1.23); C631(1.00)  LDD1005  [8]
 LDCM0408  CL20 HEK-293T C602(0.85); C631(1.11)  LDD1006  [8]
 LDCM0409  CL21 HEK-293T C602(0.70); C631(1.19)  LDD1007  [8]
 LDCM0410  CL22 HEK-293T C602(1.10); C631(1.12)  LDD1008  [8]
 LDCM0411  CL23 HEK-293T C602(0.66); C631(0.89)  LDD1009  [8]
 LDCM0412  CL24 HEK-293T C602(0.71); C631(1.03)  LDD1010  [8]
 LDCM0413  CL25 HEK-293T C602(0.83); C631(1.18)  LDD1011  [8]
 LDCM0414  CL26 HEK-293T C602(0.78); C631(1.12)  LDD1012  [8]
 LDCM0415  CL27 HEK-293T C602(0.75); C631(1.02)  LDD1013  [8]
 LDCM0416  CL28 HEK-293T C602(0.67); C631(0.94)  LDD1014  [8]
 LDCM0417  CL29 HEK-293T C602(0.80); C631(0.98)  LDD1015  [8]
 LDCM0418  CL3 HEK-293T C602(1.14); C631(1.24)  LDD1016  [8]
 LDCM0419  CL30 HEK-293T C602(0.92); C631(1.36)  LDD1017  [8]
 LDCM0420  CL31 HEK-293T C631(1.42)  LDD1018  [8]
 LDCM0421  CL32 HEK-293T C631(1.27)  LDD1019  [8]
 LDCM0422  CL33 HEK-293T C631(1.49)  LDD1020  [8]
 LDCM0423  CL34 HEK-293T C631(1.07)  LDD1021  [8]
 LDCM0424  CL35 HEK-293T C631(1.39)  LDD1022  [8]
 LDCM0425  CL36 HEK-293T C631(1.12)  LDD1023  [8]
 LDCM0426  CL37 HEK-293T C631(1.23)  LDD1024  [8]
 LDCM0428  CL39 HEK-293T C631(2.21)  LDD1026  [8]
 LDCM0429  CL4 HEK-293T C602(1.80); C631(1.19)  LDD1027  [8]
 LDCM0430  CL40 HEK-293T C631(1.45)  LDD1028  [8]
 LDCM0431  CL41 HEK-293T C631(1.93)  LDD1029  [8]
 LDCM0432  CL42 HEK-293T C631(1.66)  LDD1030  [8]
 LDCM0433  CL43 HEK-293T C631(1.84)  LDD1031  [8]
 LDCM0434  CL44 HEK-293T C631(1.29)  LDD1032  [8]
 LDCM0435  CL45 HEK-293T C631(1.81)  LDD1033  [8]
 LDCM0436  CL46 PaTu 8988t C631(0.96)  LDD1315  [8]
 LDCM0437  CL47 PaTu 8988t C631(1.00)  LDD1316  [8]
 LDCM0438  CL48 PaTu 8988t C631(1.11)  LDD1317  [8]
 LDCM0439  CL49 PaTu 8988t C631(0.92)  LDD1318  [8]
 LDCM0440  CL5 HEK-293T C602(1.24); C631(1.35)  LDD1038  [8]
 LDCM0441  CL50 PaTu 8988t C631(1.05)  LDD1320  [8]
 LDCM0442  CL51 PaTu 8988t C631(0.90)  LDD1321  [8]
 LDCM0443  CL52 PaTu 8988t C631(0.93)  LDD1322  [8]
 LDCM0444  CL53 PaTu 8988t C631(0.78)  LDD1323  [8]
 LDCM0445  CL54 PaTu 8988t C631(0.83)  LDD1324  [8]
 LDCM0446  CL55 PaTu 8988t C631(0.92)  LDD1325  [8]
 LDCM0447  CL56 PaTu 8988t C631(0.92)  LDD1326  [8]
 LDCM0448  CL57 PaTu 8988t C631(1.07)  LDD1327  [8]
 LDCM0449  CL58 PaTu 8988t C631(1.06)  LDD1328  [8]
 LDCM0450  CL59 PaTu 8988t C631(1.00)  LDD1329  [8]
 LDCM0451  CL6 HEK-293T C602(1.11); C631(1.07)  LDD1049  [8]
 LDCM0452  CL60 PaTu 8988t C631(0.95)  LDD1331  [8]
 LDCM0453  CL61 HEK-293T C631(1.38)  LDD1051  [8]
 LDCM0454  CL62 HEK-293T C631(1.69)  LDD1052  [8]
 LDCM0455  CL63 HEK-293T C631(1.55)  LDD1053  [8]
 LDCM0456  CL64 HEK-293T C631(1.15)  LDD1054  [8]
 LDCM0457  CL65 HEK-293T C631(1.54)  LDD1055  [8]
 LDCM0458  CL66 HEK-293T C631(1.24)  LDD1056  [8]
 LDCM0459  CL67 HEK-293T C631(1.19)  LDD1057  [8]
 LDCM0460  CL68 HEK-293T C631(1.17)  LDD1058  [8]
 LDCM0461  CL69 HEK-293T C631(1.32)  LDD1059  [8]
 LDCM0462  CL7 HEK-293T C602(1.62); C631(1.57)  LDD1060  [8]
 LDCM0463  CL70 HEK-293T C631(1.28)  LDD1061  [8]
 LDCM0464  CL71 HEK-293T C631(1.57)  LDD1062  [8]
 LDCM0465  CL72 HEK-293T C631(1.44)  LDD1063  [8]
 LDCM0466  CL73 HEK-293T C631(1.33)  LDD1064  [8]
 LDCM0467  CL74 HEK-293T C631(1.94)  LDD1065  [8]
 LDCM0469  CL76 HEK-293T C546(0.92); C631(1.10)  LDD1672  [9]
 LDCM0470  CL77 HEK-293T C546(0.94); C656(0.81); C631(0.96)  LDD1673  [9]
 LDCM0471  CL78 HEK-293T C546(1.20); C631(1.01); C602(1.08)  LDD1674  [9]
 LDCM0472  CL79 HEK-293T C546(1.04); C656(1.19); C721(1.19); C631(1.19)  LDD1675  [9]
 LDCM0473  CL8 HEK-293T C602(0.69)  LDD1071  [8]
 LDCM0474  CL80 HEK-293T C546(0.97); C30(1.04)  LDD1677  [9]
 LDCM0475  CL81 HEK-293T C656(1.49); C721(1.08); C631(1.06); C30(1.16)  LDD1678  [9]
 LDCM0476  CL82 HEK-293T C546(0.84); C30(1.06)  LDD1679  [9]
 LDCM0477  CL83 HEK-293T C546(1.02); C30(0.92); C602(0.92)  LDD1680  [9]
 LDCM0478  CL84 HEK-293T C656(1.14); C65(0.96)  LDD1681  [9]
 LDCM0479  CL85 HEK-293T C546(0.96); C656(1.19)  LDD1682  [9]
 LDCM0480  CL86 HEK-293T C546(1.02); C656(0.71); C721(0.99); C19(0.90)  LDD1683  [9]
 LDCM0481  CL87 HEK-293T C546(1.14); C656(0.88); C135(0.79)  LDD1684  [9]
 LDCM0482  CL88 HEK-293T C546(0.93); C631(1.16)  LDD1685  [9]
 LDCM0483  CL89 HEK-293T C546(0.97); C656(1.01); C631(0.95)  LDD1686  [9]
 LDCM0484  CL9 HEK-293T C602(0.66)  LDD1082  [8]
 LDCM0485  CL90 HEK-293T C546(0.89); C631(0.98); C602(0.98)  LDD1688  [9]
 LDCM0486  CL91 HEK-293T C631(1.12)  LDD1084  [8]
 LDCM0487  CL92 HEK-293T C631(1.11)  LDD1085  [8]
 LDCM0488  CL93 HEK-293T C631(1.09)  LDD1086  [8]
 LDCM0489  CL94 HEK-293T C631(1.60)  LDD1087  [8]
 LDCM0490  CL95 HEK-293T C631(1.78)  LDD1088  [8]
 LDCM0491  CL96 HEK-293T C631(1.32)  LDD1089  [8]
 LDCM0492  CL97 HEK-293T C631(1.17)  LDD1090  [8]
 LDCM0493  CL98 HEK-293T C631(1.16)  LDD1091  [8]
 LDCM0494  CL99 HEK-293T C631(1.16)  LDD1092  [8]
 LDCM0495  E2913 HEK-293T C546(0.99); C656(0.94); C135(0.86)  LDD1698  [9]
 LDCM0468  Fragment33 HEK-293T C631(1.81)  LDD1066  [8]
 LDCM0427  Fragment51 HEK-293T C631(1.28)  LDD1025  [8]
 LDCM0022  KB02 HEK-293T C656(0.90)  LDD1492  [9]
 LDCM0023  KB03 HEK-293T C656(1.13)  LDD1497  [9]
 LDCM0024  KB05 MSTO-211H C546(1.95)  LDD3337  [2]

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
4 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
5 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
6 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
7 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
8 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
9 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402