General Information of Target

Target ID LDTP15512
Target Name Zinc finger protein 555 (ZNF555)
Gene Name ZNF555
Gene ID 148254
Synonyms
Zinc finger protein 555
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLSPNDKMLGKLDPFYQPSVSKQKTSAEIISEARNALRTVRTQRPFTPQEAQRKLFGPAS
SRTSENRPPSSFSLHASSFESSDSRPISGTRLSPLELKPKVPASPTREEDSCFSFPKPPV
DPAKIRRVSNARARLFRAASQRALLPDRSLPPSDSKKTVESKETVMMGDSMVKINGIYLT
KSNAICHLKSHPLQLTDDGGFSEIKEQEMFKGTTSLPSHLKNGGDQGKRHARASSCPSSS
DLSRLQTKAVPKADLQEEDAEIEVDEVFWNTRIVPILRELEKEENIETVCAACTQLHHAL
EEGNMLGNKFKGRSILLKTLCKLVDVGSDSLSLKLAKIILALKVSRKNLLNVCKLIFKIS
RNEKNDSLIQNDSILESLLEVLRSEDLQTNMEAFLYCMGSIKFISGNLGFLNEMISKGAV
EILINLIKQINENIKKCGTFLPNSGHLLVQVTATLRNLVDSSLVRSKFLNISALPQLCTA
MEQYKGDKDVCTNIARIFSKLTSYRDCCTALASYSRCYALFLNLINKYQKKQDLVVRVVF
ILGNLTAKNNQAREQFSKEKGSIQTLLSLFQTFHQLDLHSQKPVGQRGEQHRAQRPPSEA
EDVLIKLTRVLANIAIHPGVGPVLAANPGIVGLLLTTLEYKSLDDCEELVINATATINNL
SYYQVKNSIIQDKKLYIAELLLKLLVSNNMDGILEAVRVFGNLSQDHDVCDFIVQNNVHR
FMMALLDAQHQDICFSACGVLLNLTVDKDKRVILKEGGGIKKLVDCLRDLGPTDWQLACL
VCKTLWNFSENITNASSCFGNEDTNTLLLLLSSFLDEELALDGSFDPDLKNYHKLHWETE
FKPVAQQLLNRIQRHHTFLEPLPIPSF
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q8NEP9
Ensemble ID
ENST00000334241.9
HGNC ID
HGNC:28382

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
DU145 SNV: p.T559I .
IPC298 SNV: p.P627S .
JURKAT SNV: p.E540K .
MCC13 SNV: p.S410F .
NCIH446 SNV: p.S125I .
RPMI8226 SNV: p.L20F .
SW756 SNV: p.Q57Ter .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C575(75.95)  LDD0209  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C606(0.89)  LDD0812  [2]
 LDCM0215  AC10 HCT 116 C594(1.40); C606(1.40)  LDD0532  [2]
 LDCM0216  AC100 HCT 116 C594(0.54); C606(0.54)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C594(0.81); C606(0.81)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C594(0.67); C606(0.67)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C594(0.61); C606(0.61)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C594(0.61); C606(0.61)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C594(1.10); C606(1.10)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C594(0.60); C606(0.60)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C594(0.80); C606(0.80)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C594(0.48); C606(0.48)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C594(0.51); C606(0.51)  LDD0542  [2]
 LDCM0226  AC11 HCT 116 C594(1.27); C606(1.27)  LDD0543  [2]
 LDCM0227  AC110 HCT 116 C594(0.35); C606(0.35)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C594(0.53); C606(0.53)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C594(0.51); C606(0.51)  LDD0546  [2]
 LDCM0230  AC113 HEK-293T C594(2.07); C606(1.53)  LDD0828  [2]
 LDCM0231  AC114 HEK-293T C594(1.29); C606(1.11)  LDD0829  [2]
 LDCM0232  AC115 HEK-293T C594(1.47); C606(1.23)  LDD0830  [2]
 LDCM0233  AC116 HEK-293T C594(1.28); C606(1.09)  LDD0831  [2]
 LDCM0234  AC117 HEK-293T C594(1.66); C606(1.17)  LDD0832  [2]
 LDCM0235  AC118 HEK-293T C594(0.90); C606(0.74)  LDD0833  [2]
 LDCM0236  AC119 HEK-293T C594(1.29); C606(0.92)  LDD0834  [2]
 LDCM0237  AC12 HCT 116 C594(0.96); C606(0.96)  LDD0554  [2]
 LDCM0238  AC120 HEK-293T C594(1.09); C606(0.84)  LDD0836  [2]
 LDCM0239  AC121 HEK-293T C594(1.50); C606(1.03)  LDD0837  [2]
 LDCM0240  AC122 HEK-293T C594(2.08); C606(1.33)  LDD0838  [2]
 LDCM0241  AC123 HEK-293T C594(1.24); C606(0.92)  LDD0839  [2]
 LDCM0242  AC124 HEK-293T C594(1.80); C606(1.18)  LDD0840  [2]
 LDCM0243  AC125 HEK-293T C594(1.38); C606(0.95)  LDD0841  [2]
 LDCM0244  AC126 HEK-293T C594(1.78); C606(1.20)  LDD0842  [2]
 LDCM0245  AC127 HEK-293T C594(2.10); C606(1.40)  LDD0843  [2]
 LDCM0246  AC128 HEK-293T C606(0.92)  LDD0844  [2]
 LDCM0247  AC129 HEK-293T C606(0.52)  LDD0845  [2]
 LDCM0249  AC130 HEK-293T C606(0.69)  LDD0847  [2]
 LDCM0250  AC131 HEK-293T C606(0.99)  LDD0848  [2]
 LDCM0251  AC132 HEK-293T C606(0.70)  LDD0849  [2]
 LDCM0252  AC133 HEK-293T C606(0.47)  LDD0850  [2]
 LDCM0253  AC134 HEK-293T C606(0.54)  LDD0851  [2]
 LDCM0254  AC135 HEK-293T C606(0.60)  LDD0852  [2]
 LDCM0255  AC136 HEK-293T C606(0.52)  LDD0853  [2]
 LDCM0256  AC137 HEK-293T C606(0.54)  LDD0854  [2]
 LDCM0257  AC138 HEK-293T C606(0.63)  LDD0855  [2]
 LDCM0258  AC139 HEK-293T C606(0.50)  LDD0856  [2]
 LDCM0259  AC14 HCT 116 C594(1.24); C606(1.24)  LDD0576  [2]
 LDCM0260  AC140 HEK-293T C606(0.51)  LDD0858  [2]
 LDCM0261  AC141 HEK-293T C606(0.50)  LDD0859  [2]
 LDCM0262  AC142 HEK-293T C606(0.49)  LDD0860  [2]
 LDCM0263  AC143 HCT 116 C594(1.35); C606(1.35)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C606(0.86); C594(1.07)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C606(0.78); C594(0.96)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C606(0.85); C594(1.05)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C594(0.91); C606(0.94)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C606(0.84); C594(0.92)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C606(0.74); C594(1.14)  LDD0586  [2]
 LDCM0270  AC15 HCT 116 C594(1.10); C606(1.10)  LDD0587  [2]
 LDCM0271  AC150 HCT 116 C594(1.34); C606(1.42)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C606(1.19); C594(1.22)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C606(1.28); C594(1.44)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C606(0.87); C594(1.21)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C594(1.28); C606(0.95)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C594(1.33); C606(1.14)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C594(1.37); C606(1.07)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C594(1.33); C606(1.01)  LDD2161  [2]
 LDCM0276  AC17 HCT 116 C594(0.72); C606(0.72)  LDD0593  [2]
 LDCM0277  AC18 HCT 116 C594(1.03); C606(1.03)  LDD0594  [2]
 LDCM0278  AC19 HCT 116 C594(1.10); C606(1.10)  LDD0595  [2]
 LDCM0279  AC2 HEK-293T C606(0.91)  LDD0877  [2]
 LDCM0280  AC20 HCT 116 C594(0.80); C606(0.80)  LDD0597  [2]
 LDCM0281  AC21 HCT 116 C594(0.75); C606(0.75)  LDD0598  [2]
 LDCM0282  AC22 HCT 116 C594(0.74); C606(0.74)  LDD0599  [2]
 LDCM0283  AC23 HCT 116 C594(0.83); C606(0.83)  LDD0600  [2]
 LDCM0284  AC24 HCT 116 C594(0.93); C606(0.93)  LDD0601  [2]
 LDCM0285  AC25 HCT 116 C594(1.07); C606(1.07)  LDD0602  [2]
 LDCM0286  AC26 HCT 116 C594(1.15); C606(1.15)  LDD0603  [2]
 LDCM0287  AC27 HCT 116 C594(2.46); C606(2.46)  LDD0604  [2]
 LDCM0288  AC28 HCT 116 C594(1.50); C606(1.50)  LDD0605  [2]
 LDCM0289  AC29 HCT 116 C594(0.98); C606(0.98)  LDD0606  [2]
 LDCM0290  AC3 HEK-293T C606(1.13)  LDD0888  [2]
 LDCM0291  AC30 HCT 116 C594(1.14); C606(1.14)  LDD0608  [2]
 LDCM0292  AC31 HCT 116 C594(1.29); C606(1.29)  LDD0609  [2]
 LDCM0293  AC32 HCT 116 C594(1.88); C606(1.88)  LDD0610  [2]
 LDCM0294  AC33 HCT 116 C594(1.51); C606(1.51)  LDD0611  [2]
 LDCM0295  AC34 HCT 116 C594(1.36); C606(1.36)  LDD0612  [2]
 LDCM0296  AC35 HCT 116 C594(0.44); C606(0.44)  LDD0613  [2]
 LDCM0297  AC36 HCT 116 C594(0.53); C606(0.53)  LDD0614  [2]
 LDCM0298  AC37 HCT 116 C594(0.35); C606(0.35)  LDD0615  [2]
 LDCM0299  AC38 HCT 116 C594(0.67); C606(0.67)  LDD0616  [2]
 LDCM0300  AC39 HCT 116 C594(0.49); C606(0.49)  LDD0617  [2]
 LDCM0301  AC4 HEK-293T C606(1.27)  LDD0899  [2]
 LDCM0302  AC40 HCT 116 C594(0.49); C606(0.49)  LDD0619  [2]
 LDCM0303  AC41 HCT 116 C594(0.42); C606(0.42)  LDD0620  [2]
 LDCM0304  AC42 HCT 116 C594(0.49); C606(0.49)  LDD0621  [2]
 LDCM0305  AC43 HCT 116 C594(0.49); C606(0.49)  LDD0622  [2]
 LDCM0306  AC44 HCT 116 C594(0.58); C606(0.58)  LDD0623  [2]
 LDCM0307  AC45 HCT 116 C594(0.50); C606(0.50)  LDD0624  [2]
 LDCM0308  AC46 HCT 116 C594(1.38); C606(1.38)  LDD0625  [2]
 LDCM0309  AC47 HCT 116 C594(1.17); C606(1.17)  LDD0626  [2]
 LDCM0310  AC48 HCT 116 C594(1.11); C606(1.11)  LDD0627  [2]
 LDCM0311  AC49 HCT 116 C594(1.27); C606(1.27)  LDD0628  [2]
 LDCM0312  AC5 HEK-293T C606(1.03)  LDD0910  [2]
 LDCM0313  AC50 HCT 116 C594(1.47); C606(1.47)  LDD0630  [2]
 LDCM0314  AC51 HCT 116 C594(1.12); C606(1.12)  LDD0631  [2]
 LDCM0315  AC52 HCT 116 C594(1.23); C606(1.23)  LDD0632  [2]
 LDCM0316  AC53 HCT 116 C594(1.71); C606(1.71)  LDD0633  [2]
 LDCM0317  AC54 HCT 116 C594(1.22); C606(1.22)  LDD0634  [2]
 LDCM0318  AC55 HCT 116 C594(1.52); C606(1.52)  LDD0635  [2]
 LDCM0319  AC56 HCT 116 C594(1.92); C606(1.92)  LDD0636  [2]
 LDCM0321  AC58 HEK-293T C575(1.10)  LDD1560  [3]
 LDCM0322  AC59 HEK-293T C575(1.01)  LDD1561  [3]
 LDCM0323  AC6 HCT 116 C594(0.99); C606(0.99)  LDD0640  [2]
 LDCM0324  AC60 HEK-293T C575(0.97)  LDD1563  [3]
 LDCM0327  AC63 HEK-293T C575(0.84)  LDD1566  [3]
 LDCM0332  AC68 HCT 116 C594(0.96); C606(0.96)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C594(0.93); C606(0.93)  LDD0650  [2]
 LDCM0334  AC7 HCT 116 C594(1.01); C606(1.01)  LDD0651  [2]
 LDCM0335  AC70 HCT 116 C594(1.01); C606(1.01)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C594(0.80); C606(0.80)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C594(0.86); C606(0.86)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C594(1.27); C606(1.27)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C594(1.16); C606(1.16)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C594(1.52); C606(1.52)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C594(1.16); C606(1.16)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C594(0.94); C606(0.94)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C594(0.87); C606(0.87)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C594(1.13); C606(1.13)  LDD0661  [2]
 LDCM0345  AC8 HCT 116 C594(1.03); C606(1.03)  LDD0662  [2]
 LDCM0346  AC80 HCT 116 C594(0.94); C606(0.94)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C594(1.09); C606(1.09)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C594(1.73); C606(1.73)  LDD0665  [2]
 LDCM0349  AC83 HEK-293T C594(1.04); C606(1.09)  LDD0947  [2]
 LDCM0350  AC84 HEK-293T C594(1.03); C606(0.76)  LDD0948  [2]
 LDCM0351  AC85 HEK-293T C594(1.00); C606(0.79)  LDD0949  [2]
 LDCM0352  AC86 HEK-293T C594(1.11); C606(0.86)  LDD0950  [2]
 LDCM0353  AC87 HEK-293T C594(1.16); C606(0.90)  LDD0951  [2]
 LDCM0354  AC88 HEK-293T C594(0.97); C606(0.71)  LDD0952  [2]
 LDCM0355  AC89 HEK-293T C594(1.08); C606(0.74)  LDD0953  [2]
 LDCM0357  AC90 HEK-293T C594(0.99); C606(0.71)  LDD0955  [2]
 LDCM0358  AC91 HEK-293T C594(1.16); C606(0.83)  LDD0956  [2]
 LDCM0359  AC92 HEK-293T C594(1.10); C606(0.87)  LDD0957  [2]
 LDCM0360  AC93 HEK-293T C594(0.88); C606(0.76)  LDD0958  [2]
 LDCM0361  AC94 HEK-293T C594(1.09); C606(0.74)  LDD0959  [2]
 LDCM0362  AC95 HEK-293T C594(1.06); C606(0.77)  LDD0960  [2]
 LDCM0363  AC96 HEK-293T C594(0.87); C606(0.79)  LDD0961  [2]
 LDCM0364  AC97 HEK-293T C594(0.81); C606(0.63)  LDD0962  [2]
 LDCM0365  AC98 HCT 116 C594(0.69); C606(0.69)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C594(0.48); C606(0.48)  LDD0683  [2]
 LDCM0248  AKOS034007472 HCT 116 C594(1.23); C606(1.23)  LDD0565  [2]
 LDCM0356  AKOS034007680 HCT 116 C594(1.28); C606(1.28)  LDD0673  [2]
 LDCM0275  AKOS034007705 HCT 116 C594(1.87); C606(1.87)  LDD0592  [2]
 LDCM0367  CL1 HCT 116 C594(1.09); C606(1.09)  LDD0684  [2]
 LDCM0368  CL10 HCT 116 C594(1.51); C606(1.51)  LDD0685  [2]
 LDCM0369  CL100 HEK-293T C606(0.86)  LDD0967  [2]
 LDCM0370  CL101 HCT 116 C594(1.42); C606(1.42)  LDD0687  [2]
 LDCM0371  CL102 HCT 116 C594(1.10); C606(1.10)  LDD0688  [2]
 LDCM0372  CL103 HCT 116 C594(1.07); C606(1.07)  LDD0689  [2]
 LDCM0373  CL104 HCT 116 C594(1.26); C606(1.26)  LDD0690  [2]
 LDCM0374  CL105 HCT 116 C594(1.18); C606(1.18)  LDD0691  [2]
 LDCM0375  CL106 HCT 116 C594(1.21); C606(1.21)  LDD0692  [2]
 LDCM0376  CL107 HCT 116 C594(0.82); C606(0.82)  LDD0693  [2]
 LDCM0377  CL108 HCT 116 C594(0.85); C606(0.85)  LDD0694  [2]
 LDCM0378  CL109 HCT 116 C594(1.24); C606(1.24)  LDD0695  [2]
 LDCM0379  CL11 HCT 116 C594(1.40); C606(1.40)  LDD0696  [2]
 LDCM0380  CL110 HCT 116 C594(1.03); C606(1.03)  LDD0697  [2]
 LDCM0381  CL111 HCT 116 C594(1.47); C606(1.47)  LDD0698  [2]
 LDCM0382  CL112 HCT 116 C594(1.15); C606(1.15)  LDD0699  [2]
 LDCM0383  CL113 HCT 116 C594(1.79); C606(1.79)  LDD0700  [2]
 LDCM0384  CL114 HCT 116 C594(3.79); C606(3.79)  LDD0701  [2]
 LDCM0385  CL115 HCT 116 C594(1.16); C606(1.16)  LDD0702  [2]
 LDCM0386  CL116 HCT 116 C594(1.55); C606(1.55)  LDD0703  [2]
 LDCM0387  CL117 HCT 116 C594(0.52); C606(0.52)  LDD0704  [2]
 LDCM0388  CL118 HCT 116 C594(0.77); C606(0.77)  LDD0705  [2]
 LDCM0389  CL119 HCT 116 C594(0.49); C606(0.49)  LDD0706  [2]
 LDCM0390  CL12 HCT 116 C594(1.62); C606(1.62)  LDD0707  [2]
 LDCM0391  CL120 HCT 116 C594(0.48); C606(0.48)  LDD0708  [2]
 LDCM0392  CL121 HCT 116 C594(2.72); C606(2.72)  LDD0709  [2]
 LDCM0393  CL122 HCT 116 C594(1.44); C606(1.44)  LDD0710  [2]
 LDCM0394  CL123 HCT 116 C594(1.32); C606(1.32)  LDD0711  [2]
 LDCM0395  CL124 HCT 116 C594(1.54); C606(1.54)  LDD0712  [2]
 LDCM0400  CL13 HCT 116 C594(1.38); C606(1.38)  LDD0717  [2]
 LDCM0401  CL14 HCT 116 C594(1.09); C606(1.09)  LDD0718  [2]
 LDCM0402  CL15 HCT 116 C594(1.56); C606(1.56)  LDD0719  [2]
 LDCM0403  CL16 HEK-293T C594(0.97)  LDD1001  [2]
 LDCM0404  CL17 HEK-293T C594(0.83)  LDD1002  [2]
 LDCM0405  CL18 HEK-293T C594(0.56)  LDD1003  [2]
 LDCM0406  CL19 HEK-293T C594(0.72)  LDD1004  [2]
 LDCM0407  CL2 HCT 116 C594(0.62); C606(0.62)  LDD0724  [2]
 LDCM0408  CL20 HEK-293T C594(0.74)  LDD1006  [2]
 LDCM0409  CL21 HEK-293T C594(0.51)  LDD1007  [2]
 LDCM0410  CL22 HEK-293T C594(0.50)  LDD1008  [2]
 LDCM0411  CL23 HEK-293T C594(1.04)  LDD1009  [2]
 LDCM0412  CL24 HEK-293T C594(0.90)  LDD1010  [2]
 LDCM0413  CL25 HEK-293T C594(0.78)  LDD1011  [2]
 LDCM0414  CL26 HEK-293T C594(0.73)  LDD1012  [2]
 LDCM0415  CL27 HEK-293T C594(0.73)  LDD1013  [2]
 LDCM0416  CL28 HEK-293T C594(0.88)  LDD1014  [2]
 LDCM0417  CL29 HEK-293T C594(0.80)  LDD1015  [2]
 LDCM0418  CL3 HCT 116 C594(0.87); C606(0.87)  LDD0735  [2]
 LDCM0419  CL30 HEK-293T C594(0.42)  LDD1017  [2]
 LDCM0420  CL31 HEK-293T C594(0.98)  LDD1018  [2]
 LDCM0421  CL32 HEK-293T C594(0.91)  LDD1019  [2]
 LDCM0422  CL33 HEK-293T C594(0.52)  LDD1020  [2]
 LDCM0423  CL34 HEK-293T C594(0.88)  LDD1021  [2]
 LDCM0424  CL35 HEK-293T C594(0.80)  LDD1022  [2]
 LDCM0425  CL36 HEK-293T C594(0.65)  LDD1023  [2]
 LDCM0426  CL37 HEK-293T C594(1.13)  LDD1024  [2]
 LDCM0428  CL39 HEK-293T C594(0.36)  LDD1026  [2]
 LDCM0429  CL4 HCT 116 C594(1.24); C606(1.24)  LDD0746  [2]
 LDCM0430  CL40 HEK-293T C594(0.60)  LDD1028  [2]
 LDCM0431  CL41 HEK-293T C594(0.46)  LDD1029  [2]
 LDCM0432  CL42 HEK-293T C594(0.38)  LDD1030  [2]
 LDCM0433  CL43 HEK-293T C594(0.46)  LDD1031  [2]
 LDCM0434  CL44 HEK-293T C594(0.72)  LDD1032  [2]
 LDCM0435  CL45 HEK-293T C594(0.41)  LDD1033  [2]
 LDCM0436  CL46 HCT 116 C594(1.12); C606(1.12)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C594(1.03); C606(1.03)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C594(1.23); C606(1.23)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C594(1.04); C606(1.04)  LDD0756  [2]
 LDCM0440  CL5 HCT 116 C594(1.06); C606(1.06)  LDD0757  [2]
 LDCM0441  CL50 HCT 116 C594(1.12); C606(1.12)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C594(1.20); C606(1.20)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C594(1.02); C606(1.02)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C594(1.12); C606(1.12)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C594(0.96); C606(0.96)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C594(0.80); C606(0.80)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C594(0.86); C606(0.86)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C594(1.02); C606(1.02)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C594(1.06); C606(1.06)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C594(1.15); C606(1.15)  LDD0767  [2]
 LDCM0451  CL6 HCT 116 C594(1.49); C606(1.49)  LDD0768  [2]
 LDCM0452  CL60 HCT 116 C594(0.95); C606(0.95)  LDD0769  [2]
 LDCM0458  CL66 HEK-293T C575(1.01)  LDD1661  [3]
 LDCM0459  CL67 HEK-293T C575(1.06)  LDD1662  [3]
 LDCM0460  CL68 HEK-293T C575(1.12)  LDD1663  [3]
 LDCM0462  CL7 HCT 116 C594(1.45); C606(1.45)  LDD0779  [2]
 LDCM0464  CL71 HEK-293T C575(1.02)  LDD1667  [3]
 LDCM0469  CL76 HEK-293T C594(0.78)  LDD1067  [2]
 LDCM0470  CL77 HEK-293T C594(0.71)  LDD1068  [2]
 LDCM0471  CL78 HEK-293T C594(0.62)  LDD1069  [2]
 LDCM0472  CL79 HEK-293T C594(0.63)  LDD1070  [2]
 LDCM0473  CL8 HCT 116 C594(1.28); C606(1.28)  LDD0790  [2]
 LDCM0474  CL80 HEK-293T C594(0.74)  LDD1072  [2]
 LDCM0475  CL81 HEK-293T C594(0.66)  LDD1073  [2]
 LDCM0476  CL82 HEK-293T C594(0.96)  LDD1074  [2]
 LDCM0477  CL83 HEK-293T C594(0.98)  LDD1075  [2]
 LDCM0478  CL84 HEK-293T C594(0.70)  LDD1076  [2]
 LDCM0479  CL85 HEK-293T C594(0.82)  LDD1077  [2]
 LDCM0480  CL86 HEK-293T C594(0.55)  LDD1078  [2]
 LDCM0481  CL87 HEK-293T C594(0.70)  LDD1079  [2]
 LDCM0482  CL88 HEK-293T C594(0.83)  LDD1080  [2]
 LDCM0483  CL89 HEK-293T C594(0.62)  LDD1081  [2]
 LDCM0484  CL9 HCT 116 C594(1.09); C606(1.09)  LDD0801  [2]
 LDCM0485  CL90 HEK-293T C594(0.72)  LDD1083  [2]
 LDCM0486  CL91 HEK-293T C606(1.32)  LDD1084  [2]
 LDCM0487  CL92 HEK-293T C606(1.25)  LDD1085  [2]
 LDCM0488  CL93 HEK-293T C606(0.88)  LDD1086  [2]
 LDCM0489  CL94 HEK-293T C606(0.67)  LDD1087  [2]
 LDCM0490  CL95 HEK-293T C606(0.58)  LDD1088  [2]
 LDCM0491  CL96 HEK-293T C606(1.01)  LDD1089  [2]
 LDCM0492  CL97 HEK-293T C606(1.25)  LDD1090  [2]
 LDCM0493  CL98 HEK-293T C606(1.22)  LDD1091  [2]
 LDCM0494  CL99 HEK-293T C606(1.21)  LDD1092  [2]
 LDCM0427  Fragment51 HEK-293T C594(0.79)  LDD1025  [2]
 LDCM0022  KB02 HEK-293T C575(0.97)  LDD1492  [3]
 LDCM0023  KB03 Jurkat C575(75.95)  LDD0209  [1]
 LDCM0024  KB05 SKMEL24 C575(1.84)  LDD3323  [4]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cyclin-D1-binding protein 1 (CCNDBP1) CCNDBP1 family O95273
Keratin-associated protein 10-7 (KRTAP10-7) KRTAP type 10 family P60409
Centrosomal protein of 70 kDa (CEP70) . Q8NHQ1

References

1 Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
4 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840