Details of the Target

General Information of Target

Target ID LDTP15162
Target Name Leucine-rich repeats and immunoglobulin-like domains protein 3 (LRIG3)
Gene Name LRIG3
Gene ID 121227
Synonyms
LIG3; Leucine-rich repeats and immunoglobulin-like domains protein 3; LIG-3
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MARMSFVIAACQLVLGLLMTSLTESSIQNSECPQLCVCEIRPWFTPQSTYREATTVDCND
LRLTRIPSNLSSDTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQ
LTTLHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLK
VIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDS
LESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGEL
VSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESL
PNLREISIHSNPLRCDCVIHWINSNKTNIRFMEPLSMFCAMPPEYKGHQVKEVLIQDSSE
QCLPMISHDSFPNRLNVDIGTTVFLDCRAMAEPEPEIYWVTPIGNKITVETLSDKYKLSS
EGTLEISNIQIEDSGRYTCVAQNVQGADTRVATIKVNGTLLDGTQVLKIYVKQTESHSIL
VSWKVNSNVMTSNLKWSSATMKIDNPHITYTARVPVDVHEYNLTHLQPSTDYEVCLTVSN
IHQQTQKSCVNVTTKNAAFAVDISDQETSTALAAVMGSMFAVISLASIAVYFAKRFKRKN
YHHSLKKYMQKTSSIPLNELYPPLINLWEGDSEKDKDGSADTKPTQVDTSRSYYMW
Target Bioclass
Immunoglobulin
Subcellular location
Cell membrane
Function
May play a role in craniofacial and inner ear morphogenesis during embryonic development. May act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1.
Uniprot ID
Q6UXM1
Ensemble ID
ENST00000320743.8
HGNC ID
HGNC:30991

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
ABC1 Substitution: p.Q218Ter .
EFO27 SNV: p.E741D .
HEC1 SNV: p.W730Ter .
HEC1B SNV: p.W730Ter .
HUH28 SNV: p.H975Y .
KNS42 SNV: p.R390L .
KP4 SNV: p.A24S .
MDST8 SNV: p.V755M .
MSTO211H SNV: p.A1029V .
NCIH1792 SNV: p.S1030Ter .
REH SNV: p.A298T .
RL952 SNV: p.Q247K .
SW480 SNV: p.I565F .
U937 SNV: p.G640W .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C53(0.78); C60(0.78)  LDD0533  [1]
IPM
 Probe Info  		C1098(0.00); C973(0.00); C1062(0.00)  LDD2156  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C60(1.23); C53(2.78)  LDD0812  [1]
 LDCM0215  AC10 HEK-293T C1098(1.19); C353(1.02); C493(1.04)  LDD1508  [3]
 LDCM0216  AC100 HCT 116 C53(0.78); C60(0.78)  LDD0533  [1]
 LDCM0217  AC101 HCT 116 C53(0.90); C60(0.90)  LDD0534  [1]
 LDCM0218  AC102 HCT 116 C53(0.56); C60(0.56)  LDD0535  [1]
 LDCM0219  AC103 HCT 116 C53(0.68); C60(0.68)  LDD0536  [1]
 LDCM0220  AC104 HCT 116 C53(0.73); C60(0.73)  LDD0537  [1]
 LDCM0221  AC105 HCT 116 C53(0.67); C60(0.67)  LDD0538  [1]
 LDCM0222  AC106 HCT 116 C53(0.72); C60(0.72)  LDD0539  [1]
 LDCM0223  AC107 HCT 116 C53(0.49); C60(0.80)  LDD0540  [1]
 LDCM0224  AC108 HCT 116 C53(0.95); C60(0.49)  LDD0541  [1]
 LDCM0225  AC109 HCT 116 C53(1.03); C60(0.53)  LDD0542  [1]
 LDCM0226  AC11 HEK-293T C1098(1.03); C493(0.98); C53(1.13)  LDD1509  [3]
 LDCM0227  AC110 HCT 116 C53(0.99); C60(0.76)  LDD0544  [1]
 LDCM0228  AC111 HCT 116 C53(1.03); C60(0.61)  LDD0545  [1]
 LDCM0229  AC112 HCT 116 C53(0.61); C60(0.78)  LDD0546  [1]
 LDCM0230  AC113 HEK-293T C53(0.72)  LDD0828  [1]
 LDCM0231  AC114 HEK-293T C53(1.12)  LDD0829  [1]
 LDCM0232  AC115 HEK-293T C53(1.07)  LDD0830  [1]
 LDCM0233  AC116 HEK-293T C53(1.19)  LDD0831  [1]
 LDCM0234  AC117 HEK-293T C53(1.19)  LDD0832  [1]
 LDCM0235  AC118 HEK-293T C53(1.15)  LDD0833  [1]
 LDCM0236  AC119 HEK-293T C53(1.83)  LDD0834  [1]
 LDCM0237  AC12 HEK-293T C1098(1.13); C47(1.08)  LDD1510  [3]
 LDCM0238  AC120 HEK-293T C53(1.09)  LDD0836  [1]
 LDCM0239  AC121 HEK-293T C53(0.95)  LDD0837  [1]
 LDCM0240  AC122 HEK-293T C53(1.12)  LDD0838  [1]
 LDCM0241  AC123 HEK-293T C53(1.18)  LDD0839  [1]
 LDCM0242  AC124 HEK-293T C53(1.51)  LDD0840  [1]
 LDCM0243  AC125 HEK-293T C53(1.52)  LDD0841  [1]
 LDCM0244  AC126 HEK-293T C53(1.30)  LDD0842  [1]
 LDCM0245  AC127 HEK-293T C53(2.04)  LDD0843  [1]
 LDCM0246  AC128 HEK-293T C60(0.88); C53(0.73)  LDD0844  [1]
 LDCM0247  AC129 HEK-293T C60(1.32); C53(1.19)  LDD0845  [1]
 LDCM0249  AC130 HEK-293T C60(1.35); C53(1.08)  LDD0847  [1]
 LDCM0250  AC131 HEK-293T C60(0.96); C53(0.89)  LDD0848  [1]
 LDCM0251  AC132 HEK-293T C60(1.22); C53(1.10)  LDD0849  [1]
 LDCM0252  AC133 HEK-293T C60(1.43); C53(1.24)  LDD0850  [1]
 LDCM0253  AC134 HEK-293T C60(1.33); C53(1.74)  LDD0851  [1]
 LDCM0254  AC135 HEK-293T C60(1.42); C53(0.94)  LDD0852  [1]
 LDCM0255  AC136 HEK-293T C60(1.38); C53(1.21)  LDD0853  [1]
 LDCM0256  AC137 HEK-293T C60(2.02); C53(1.27)  LDD0854  [1]
 LDCM0257  AC138 HEK-293T C60(2.31); C53(1.29)  LDD0855  [1]
 LDCM0258  AC139 HEK-293T C60(1.86); C53(1.32)  LDD0856  [1]
 LDCM0259  AC14 HEK-293T C1098(1.06); C493(1.18); C47(1.05)  LDD1512  [3]
 LDCM0260  AC140 HEK-293T C60(1.55); C53(1.37)  LDD0858  [1]
 LDCM0261  AC141 HEK-293T C60(1.92); C53(1.73)  LDD0859  [1]
 LDCM0262  AC142 HEK-293T C60(1.70); C53(1.59)  LDD0860  [1]
 LDCM0263  AC143 HCT 116 C53(1.38); C60(1.38)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C53(1.38); C60(1.38)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C53(1.15); C60(1.15)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C53(1.69); C60(1.69)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C53(1.55); C60(1.55)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C53(1.44); C60(1.44)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C53(1.08); C60(1.08)  LDD0586  [1]
 LDCM0270  AC15 HEK-293T C1098(1.16); C493(0.93)  LDD1513  [3]
 LDCM0271  AC150 HCT 116 C53(2.07); C60(2.07)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C53(1.03); C60(1.03)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C53(1.12); C60(1.12)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C53(1.48); C60(1.48)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C53(1.69); C60(1.69)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C53(1.12); C60(1.12)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C53(1.30); C60(1.30)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C53(1.62); C60(1.62)  LDD2161  [1]
 LDCM0276  AC17 HEK-293T C53(1.63)  LDD0874  [1]
 LDCM0277  AC18 HEK-293T C53(1.20)  LDD0875  [1]
 LDCM0278  AC19 HEK-293T C53(1.60)  LDD0876  [1]
 LDCM0279  AC2 HEK-293T C60(1.57); C53(1.67)  LDD0877  [1]
 LDCM0280  AC20 HEK-293T C53(1.54)  LDD0878  [1]
 LDCM0281  AC21 HEK-293T C53(1.47)  LDD0879  [1]
 LDCM0282  AC22 HEK-293T C53(2.02)  LDD0880  [1]
 LDCM0283  AC23 HEK-293T C53(2.02)  LDD0881  [1]
 LDCM0284  AC24 HEK-293T C53(1.93)  LDD0882  [1]
 LDCM0285  AC25 HEK-293T C53(1.65)  LDD0883  [1]
 LDCM0286  AC26 HEK-293T C53(1.61)  LDD0884  [1]
 LDCM0287  AC27 HEK-293T C53(1.46)  LDD0885  [1]
 LDCM0288  AC28 HEK-293T C53(1.90)  LDD0886  [1]
 LDCM0289  AC29 HEK-293T C53(1.56)  LDD0887  [1]
 LDCM0290  AC3 HEK-293T C60(1.25); C53(1.08)  LDD0888  [1]
 LDCM0291  AC30 HEK-293T C53(1.72)  LDD0889  [1]
 LDCM0292  AC31 HEK-293T C53(1.65)  LDD0890  [1]
 LDCM0293  AC32 HEK-293T C53(1.49)  LDD0891  [1]
 LDCM0294  AC33 HEK-293T C53(1.67)  LDD0892  [1]
 LDCM0295  AC34 HEK-293T C53(1.81)  LDD0893  [1]
 LDCM0296  AC35 HEK-293T C1098(0.93); C493(0.95); C53(1.22)  LDD1535  [3]
 LDCM0297  AC36 HEK-293T C1098(1.01); C47(0.96)  LDD1536  [3]
 LDCM0298  AC37 HEK-293T C1098(1.04); C493(0.95); C767(0.94); C47(0.96)  LDD1537  [3]
 LDCM0299  AC38 HEK-293T C1098(0.95); C493(1.09); C47(0.98)  LDD1538  [3]
 LDCM0300  AC39 HEK-293T C1098(1.20); C493(0.98)  LDD1539  [3]
 LDCM0301  AC4 HEK-293T C60(1.17); C53(1.28)  LDD0899  [1]
 LDCM0302  AC40 HEK-293T C1098(0.92); C948(1.78); C493(1.18)  LDD1541  [3]
 LDCM0303  AC41 HEK-293T C1098(1.08); C353(1.08); C493(1.16)  LDD1542  [3]
 LDCM0304  AC42 HEK-293T C1098(1.10); C353(1.06); C493(1.09)  LDD1543  [3]
 LDCM0305  AC43 HEK-293T C1098(0.96); C493(0.91); C53(1.22)  LDD1544  [3]
 LDCM0306  AC44 HEK-293T C1098(1.08); C47(1.01)  LDD1545  [3]
 LDCM0307  AC45 HEK-293T C1098(1.06); C493(1.13); C767(1.37); C47(1.10)  LDD1546  [3]
 LDCM0308  AC46 HEK-293T C53(1.01)  LDD0906  [1]
 LDCM0309  AC47 HEK-293T C53(1.33)  LDD0907  [1]
 LDCM0310  AC48 HEK-293T C53(1.04)  LDD0908  [1]
 LDCM0311  AC49 HEK-293T C53(1.18)  LDD0909  [1]
 LDCM0312  AC5 HEK-293T C60(1.16); C53(2.05)  LDD0910  [1]
 LDCM0313  AC50 HEK-293T C53(1.04)  LDD0911  [1]
 LDCM0314  AC51 HEK-293T C53(1.06)  LDD0912  [1]
 LDCM0315  AC52 HEK-293T C53(1.33)  LDD0913  [1]
 LDCM0316  AC53 HEK-293T C53(1.18)  LDD0914  [1]
 LDCM0317  AC54 HEK-293T C53(1.11)  LDD0915  [1]
 LDCM0318  AC55 HEK-293T C53(1.54)  LDD0916  [1]
 LDCM0319  AC56 HEK-293T C53(1.74)  LDD0917  [1]
 LDCM0320  AC57 HEK-293T C60(1.16)  LDD0918  [1]
 LDCM0321  AC58 HEK-293T C60(1.08)  LDD0919  [1]
 LDCM0322  AC59 HEK-293T C60(1.03)  LDD0920  [1]
 LDCM0323  AC6 HEK-293T C1098(0.99); C493(1.29); C47(0.97)  LDD1562  [3]
 LDCM0324  AC60 HEK-293T C60(0.92)  LDD0922  [1]
 LDCM0325  AC61 HEK-293T C60(1.61)  LDD0923  [1]
 LDCM0326  AC62 HEK-293T C60(1.18)  LDD0924  [1]
 LDCM0327  AC63 HEK-293T C60(1.36)  LDD0925  [1]
 LDCM0328  AC64 HEK-293T C60(1.09)  LDD0926  [1]
 LDCM0329  AC65 HEK-293T C60(1.51)  LDD0927  [1]
 LDCM0330  AC66 HEK-293T C60(1.24)  LDD0928  [1]
 LDCM0331  AC67 HEK-293T C60(1.41)  LDD0929  [1]
 LDCM0332  AC68 HCT 116 C53(1.19); C60(1.19)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C53(0.98); C60(0.98)  LDD0650  [1]
 LDCM0334  AC7 HEK-293T C1098(1.07); C493(0.99)  LDD1568  [3]
 LDCM0335  AC70 HCT 116 C53(1.19); C60(1.19)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C53(0.81); C60(0.81)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C53(0.94); C60(0.94)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C53(0.77); C60(0.77)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C53(0.81); C60(0.81)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C53(0.75); C60(0.75)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C53(0.88); C60(0.88)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C53(0.98); C60(0.98)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C53(0.84); C60(0.84)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C53(1.12); C60(1.12)  LDD0661  [1]
 LDCM0345  AC8 HEK-293T C1098(0.89); C948(1.35); C493(1.13)  LDD1569  [3]
 LDCM0346  AC80 HCT 116 C53(0.83); C60(0.83)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C53(0.76); C60(0.76)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C53(0.88); C60(0.88)  LDD0665  [1]
 LDCM0349  AC83 HCT 116 C53(0.95); C60(0.95)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C53(0.96); C60(0.96)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C53(1.10); C60(1.10)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C53(1.16); C60(1.16)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C53(1.08); C60(1.08)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C53(1.42); C60(1.42)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C53(1.06); C60(1.06)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C53(1.10); C60(1.10)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C53(1.00); C60(1.00)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C53(1.23); C60(1.23)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C53(1.17); C60(1.17)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C53(1.19); C60(1.19)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C53(1.16); C60(1.16)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C53(1.07); C60(1.07)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C53(0.90); C60(0.90)  LDD0681  [1]
 LDCM0365  AC98 HCT 116 C53(0.46); C60(0.46)  LDD0682  [1]
 LDCM0366  AC99 HCT 116 C53(0.66); C60(0.66)  LDD0683  [1]
 LDCM0248  AKOS034007472 HEK-293T C1098(1.07); C493(1.12); C767(0.94); C47(1.04)  LDD1511  [3]
 LDCM0356  AKOS034007680 HEK-293T C1098(1.03); C353(1.01); C493(1.23)  LDD1570  [3]
 LDCM0275  AKOS034007705 HEK-293T C1098(1.01); C948(0.93); C493(1.16)  LDD1514  [3]
 LDCM0367  CL1 HEK-293T C60(0.76); C53(1.62)  LDD0965  [1]
 LDCM0368  CL10 HEK-293T C60(20.00); C53(2.28)  LDD0966  [1]
 LDCM0369  CL100 HEK-293T C60(1.52); C53(1.59)  LDD0967  [1]
 LDCM0370  CL101 HEK-293T C1098(0.99); C353(1.09); C47(1.14)  LDD1574  [3]
 LDCM0371  CL102 HEK-293T C1098(1.25); C353(0.99)  LDD1575  [3]
 LDCM0372  CL103 HEK-293T C493(1.10)  LDD1576  [3]
 LDCM0373  CL104 HEK-293T C1098(1.05); C493(1.03); C51(1.12)  LDD1577  [3]
 LDCM0374  CL105 HEK-293T C53(1.12)  LDD0972  [1]
 LDCM0375  CL106 HEK-293T C53(1.19)  LDD0973  [1]
 LDCM0376  CL107 HEK-293T C53(1.51)  LDD0974  [1]
 LDCM0377  CL108 HEK-293T C53(0.94)  LDD0975  [1]
 LDCM0378  CL109 HEK-293T C53(1.29)  LDD0976  [1]
 LDCM0379  CL11 HEK-293T C60(2.43); C53(1.81)  LDD0977  [1]
 LDCM0380  CL110 HEK-293T C53(1.38)  LDD0978  [1]
 LDCM0381  CL111 HEK-293T C53(2.15)  LDD0979  [1]
 LDCM0382  CL112 HEK-293T C53(1.49)  LDD0980  [1]
 LDCM0383  CL113 HEK-293T C53(1.53)  LDD0981  [1]
 LDCM0384  CL114 HEK-293T C53(2.04)  LDD0982  [1]
 LDCM0385  CL115 HEK-293T C53(2.09)  LDD0983  [1]
 LDCM0386  CL116 HEK-293T C53(2.33)  LDD0984  [1]
 LDCM0387  CL117 HEK-293T C1098(0.99); C353(1.11); C47(0.96)  LDD1591  [3]
 LDCM0388  CL118 HEK-293T C1098(1.21); C353(1.19)  LDD1592  [3]
 LDCM0389  CL119 HEK-293T C493(1.22)  LDD1593  [3]
 LDCM0390  CL12 HEK-293T C60(1.20); C53(1.25)  LDD0988  [1]
 LDCM0391  CL120 HEK-293T C1098(1.02); C493(1.27); C51(1.09)  LDD1595  [3]
 LDCM0392  CL121 HEK-293T C53(1.44)  LDD0990  [1]
 LDCM0393  CL122 HEK-293T C53(1.44)  LDD0991  [1]
 LDCM0394  CL123 HEK-293T C53(1.04)  LDD0992  [1]
 LDCM0395  CL124 HEK-293T C53(1.77)  LDD0993  [1]
 LDCM0396  CL125 HEK-293T C60(1.14)  LDD0994  [1]
 LDCM0397  CL126 HEK-293T C60(1.41)  LDD0995  [1]
 LDCM0398  CL127 HEK-293T C60(1.04)  LDD0996  [1]
 LDCM0399  CL128 HEK-293T C60(1.10)  LDD0997  [1]
 LDCM0400  CL13 HEK-293T C60(0.74); C53(1.17)  LDD0998  [1]
 LDCM0401  CL14 HEK-293T C60(2.20); C53(1.68)  LDD0999  [1]
 LDCM0402  CL15 HEK-293T C60(1.51); C53(1.43)  LDD1000  [1]
 LDCM0403  CL16 HEK-293T C53(1.58)  LDD1001  [1]
 LDCM0404  CL17 HEK-293T C53(0.85)  LDD1002  [1]
 LDCM0405  CL18 HEK-293T C53(1.34)  LDD1003  [1]
 LDCM0406  CL19 HEK-293T C53(1.18)  LDD1004  [1]
 LDCM0407  CL2 HEK-293T C60(1.16); C53(1.30)  LDD1005  [1]
 LDCM0408  CL20 HEK-293T C53(1.19)  LDD1006  [1]
 LDCM0409  CL21 HEK-293T C53(1.07)  LDD1007  [1]
 LDCM0410  CL22 HEK-293T C53(0.71)  LDD1008  [1]
 LDCM0411  CL23 HEK-293T C53(0.72)  LDD1009  [1]
 LDCM0412  CL24 HEK-293T C53(1.15)  LDD1010  [1]
 LDCM0413  CL25 HEK-293T C53(1.01)  LDD1011  [1]
 LDCM0414  CL26 HEK-293T C53(0.78)  LDD1012  [1]
 LDCM0415  CL27 HEK-293T C53(0.94)  LDD1013  [1]
 LDCM0416  CL28 HEK-293T C53(0.87)  LDD1014  [1]
 LDCM0417  CL29 HEK-293T C53(0.97)  LDD1015  [1]
 LDCM0418  CL3 HEK-293T C60(0.87); C53(1.31)  LDD1016  [1]
 LDCM0419  CL30 HEK-293T C53(0.89)  LDD1017  [1]
 LDCM0420  CL31 HEK-293T C53(1.45)  LDD1018  [1]
 LDCM0421  CL32 HEK-293T C53(1.52)  LDD1019  [1]
 LDCM0422  CL33 HEK-293T C53(1.23)  LDD1020  [1]
 LDCM0423  CL34 HEK-293T C53(1.50)  LDD1021  [1]
 LDCM0424  CL35 HEK-293T C53(2.15)  LDD1022  [1]
 LDCM0425  CL36 HEK-293T C53(1.01)  LDD1023  [1]
 LDCM0426  CL37 HEK-293T C53(1.39)  LDD1024  [1]
 LDCM0428  CL39 HEK-293T C53(2.15)  LDD1026  [1]
 LDCM0429  CL4 HEK-293T C60(0.94); C53(1.22)  LDD1027  [1]
 LDCM0430  CL40 HEK-293T C53(1.29)  LDD1028  [1]
 LDCM0431  CL41 HEK-293T C53(2.35)  LDD1029  [1]
 LDCM0432  CL42 HEK-293T C53(1.94)  LDD1030  [1]
 LDCM0433  CL43 HEK-293T C53(1.36)  LDD1031  [1]
 LDCM0434  CL44 HEK-293T C53(1.97)  LDD1032  [1]
 LDCM0435  CL45 HEK-293T C53(1.70)  LDD1033  [1]
 LDCM0436  CL46 HEK-293T C53(1.80)  LDD1034  [1]
 LDCM0437  CL47 HEK-293T C53(1.29)  LDD1035  [1]
 LDCM0438  CL48 HEK-293T C53(1.30)  LDD1036  [1]
 LDCM0439  CL49 HEK-293T C53(1.13)  LDD1037  [1]
 LDCM0440  CL5 HEK-293T C60(1.60); C53(1.85)  LDD1038  [1]
 LDCM0441  CL50 HEK-293T C53(1.14)  LDD1039  [1]
 LDCM0442  CL51 HEK-293T C53(0.77)  LDD1040  [1]
 LDCM0443  CL52 HEK-293T C53(0.99)  LDD1041  [1]
 LDCM0444  CL53 HEK-293T C53(0.95)  LDD1042  [1]
 LDCM0445  CL54 HEK-293T C53(0.95)  LDD1043  [1]
 LDCM0446  CL55 HEK-293T C53(1.20)  LDD1044  [1]
 LDCM0447  CL56 HEK-293T C53(0.93)  LDD1045  [1]
 LDCM0448  CL57 HEK-293T C53(0.89)  LDD1046  [1]
 LDCM0449  CL58 HEK-293T C53(0.81)  LDD1047  [1]
 LDCM0450  CL59 HEK-293T C53(1.37)  LDD1048  [1]
 LDCM0451  CL6 HEK-293T C60(0.74); C53(1.08)  LDD1049  [1]
 LDCM0452  CL60 HEK-293T C53(1.50)  LDD1050  [1]
 LDCM0453  CL61 HEK-293T C53(2.05)  LDD1051  [1]
 LDCM0454  CL62 HEK-293T C53(1.94)  LDD1052  [1]
 LDCM0455  CL63 HEK-293T C53(1.23)  LDD1053  [1]
 LDCM0456  CL64 HEK-293T C53(1.38)  LDD1054  [1]
 LDCM0457  CL65 HEK-293T C53(1.36)  LDD1055  [1]
 LDCM0458  CL66 HEK-293T C53(1.15)  LDD1056  [1]
 LDCM0459  CL67 HEK-293T C53(1.36)  LDD1057  [1]
 LDCM0460  CL68 HEK-293T C53(1.42)  LDD1058  [1]
 LDCM0461  CL69 HEK-293T C53(1.19)  LDD1059  [1]
 LDCM0462  CL7 HEK-293T C60(1.55); C53(1.56)  LDD1060  [1]
 LDCM0463  CL70 HEK-293T C53(1.04)  LDD1061  [1]
 LDCM0464  CL71 HEK-293T C53(1.34)  LDD1062  [1]
 LDCM0465  CL72 HEK-293T C53(2.46)  LDD1063  [1]
 LDCM0466  CL73 HEK-293T C53(1.40)  LDD1064  [1]
 LDCM0467  CL74 HEK-293T C53(2.61)  LDD1065  [1]
 LDCM0469  CL76 HEK-293T C1098(1.00); C493(1.08); C51(1.20)  LDD1672  [3]
 LDCM0470  CL77 HEK-293T C1098(1.06); C353(1.08); C493(1.04)  LDD1673  [3]
 LDCM0471  CL78 HEK-293T C1098(1.15); C353(1.19); C493(1.06)  LDD1674  [3]
 LDCM0472  CL79 HEK-293T C1098(1.11); C493(0.82); C53(1.12)  LDD1675  [3]
 LDCM0473  CL8 HEK-293T C60(0.98); C53(0.89)  LDD1071  [1]
 LDCM0474  CL80 HEK-293T C1098(1.05); C47(1.30)  LDD1677  [3]
 LDCM0475  CL81 HEK-293T C1098(1.15); C493(1.08); C767(1.14); C47(1.49)  LDD1678  [3]
 LDCM0476  CL82 HEK-293T C1098(1.14); C493(1.00); C47(1.46)  LDD1679  [3]
 LDCM0477  CL83 HEK-293T C1098(1.28); C493(1.14)  LDD1680  [3]
 LDCM0478  CL84 HEK-293T C1098(0.92); C948(1.14); C493(0.88)  LDD1681  [3]
 LDCM0479  CL85 HEK-293T C1098(1.00); C353(1.15); C47(1.02)  LDD1682  [3]
 LDCM0480  CL86 HEK-293T C1098(1.08); C353(1.05)  LDD1683  [3]
 LDCM0481  CL87 HEK-293T C493(0.98)  LDD1684  [3]
 LDCM0482  CL88 HEK-293T C1098(0.94); C493(1.28); C51(1.06)  LDD1685  [3]
 LDCM0483  CL89 HEK-293T C1098(1.05); C353(1.12); C493(1.13)  LDD1686  [3]
 LDCM0484  CL9 HEK-293T C60(1.11); C53(0.90)  LDD1082  [1]
 LDCM0485  CL90 HEK-293T C1098(1.54); C353(1.21); C493(1.22)  LDD1688  [3]
 LDCM0486  CL91 HEK-293T C60(0.85); C53(1.99)  LDD1084  [1]
 LDCM0487  CL92 HEK-293T C60(1.04); C53(1.32)  LDD1085  [1]
 LDCM0488  CL93 HEK-293T C60(1.31); C53(1.31)  LDD1086  [1]
 LDCM0489  CL94 HEK-293T C60(1.80); C53(2.02)  LDD1087  [1]
 LDCM0490  CL95 HEK-293T C60(1.64); C53(1.75)  LDD1088  [1]
 LDCM0491  CL96 HEK-293T C60(1.18); C53(1.91)  LDD1089  [1]
 LDCM0492  CL97 HEK-293T C60(1.16); C53(2.08)  LDD1090  [1]
 LDCM0493  CL98 HEK-293T C60(1.50); C53(1.50)  LDD1091  [1]
 LDCM0494  CL99 HEK-293T C60(1.36); C53(1.07)  LDD1092  [1]
 LDCM0495  E2913 HEK-293T C493(1.00)  LDD1698  [3]
 LDCM0468  Fragment33 HEK-293T C53(1.57)  LDD1066  [1]
 LDCM0427  Fragment51 HEK-293T C53(1.40)  LDD1025  [1]
 LDCM0022  KB02 HEK-293T C1062(0.87); C948(0.95); C493(0.89)  LDD1492  [3]
 LDCM0023  KB03 HEK-293T C1062(0.95); C948(1.01); C493(1.00)  LDD1497  [3]
 LDCM0024  KB05 HEK-293T C1062(0.86); C948(0.91); C493(0.90)  LDD1502  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1) . Q96JA1

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
3 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402