Details of the Target

General Information of Target

Target ID LDTP14165
Target Name Melanoma-associated antigen D1 (MAGED1)
Gene Name MAGED1
Gene ID 9500
Synonyms
NRAGE; Melanoma-associated antigen D1; MAGE tumor antigen CCF; MAGE-D1 antigen; Neurotrophin receptor-interacting MAGE homolog
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MAFTLYSLLQAALLCVNAIAVLHEERFLKNIGWGTDQGIGGFGEEPGIKSQLMNLIRSVR
TVMRVPLIIVNSIAIVLLLLFG
Target Bioclass
Other
Subcellular location
Cytoplasm
Function
Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rhythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as BMAL1 and NFIL3, induced, or NR1D1, repressed.
Uniprot ID
Q9Y5V3
Ensemble ID
ENST00000326587.12
HGNC ID
HGNC:6813

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AN3CA SNV: p.V280I DBIA    Probe Info 
CCK81 Deletion: p.S451LfsTer32 DBIA    Probe Info 
HKGZCC SNV: p.I501V .
IGR1 SNV: p.A16S DBIA    Probe Info 
JM1 SNV: p.T316A .
JVM3 SNV: p.R737G .
NCIH1048 SNV: p.W275R .
NCIH1993 SNV: p.W302L .
SW403 SNV: p.S643I .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 12 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
TH216
 Probe Info  		Y738(20.00)  LDD0259  [2]
IPM
 Probe Info  		N.A.  LDD0241  [3]
HPAP
 Probe Info  		3.47  LDD0062  [4]
DBIA
 Probe Info  		C517(4.67)  LDD0209  [5]
HHS-475
 Probe Info  		Y509(1.50)  LDD0264  [6]
HHS-465
 Probe Info  		Y509(10.00)  LDD2237  [7]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [8]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [8]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [8]
SF
 Probe Info  		N.A.  LDD0028  [9]
AOyne
 Probe Info  		11.10  LDD0443  [10]
PAL-AfBPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe11
 Probe Info  		20.00  LDD0471  [11]
FFF probe13
 Probe Info  		20.00  LDD0475  [11]
FFF probe14
 Probe Info  		20.00  LDD0477  [11]
FFF probe2
 Probe Info  		20.00  LDD0463  [11]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C517(0.96)  LDD1507  [12]
 LDCM0215  AC10 HEK-293T C517(0.93)  LDD1508  [12]
 LDCM0226  AC11 HEK-293T C517(0.99)  LDD1509  [12]
 LDCM0237  AC12 HEK-293T C517(0.99)  LDD1510  [12]
 LDCM0259  AC14 HEK-293T C517(1.08)  LDD1512  [12]
 LDCM0270  AC15 HEK-293T C517(1.03)  LDD1513  [12]
 LDCM0276  AC17 HEK-293T C517(0.91)  LDD1515  [12]
 LDCM0277  AC18 HEK-293T C517(0.99)  LDD1516  [12]
 LDCM0278  AC19 HEK-293T C517(1.00)  LDD1517  [12]
 LDCM0279  AC2 HEK-293T C517(0.97)  LDD1518  [12]
 LDCM0280  AC20 HEK-293T C517(1.02)  LDD1519  [12]
 LDCM0281  AC21 HEK-293T C517(1.00)  LDD1520  [12]
 LDCM0282  AC22 HEK-293T C517(0.98)  LDD1521  [12]
 LDCM0283  AC23 HEK-293T C517(1.04)  LDD1522  [12]
 LDCM0284  AC24 HEK-293T C517(0.95)  LDD1523  [12]
 LDCM0285  AC25 HEK-293T C517(0.95)  LDD1524  [12]
 LDCM0286  AC26 HEK-293T C517(0.99)  LDD1525  [12]
 LDCM0287  AC27 HEK-293T C517(1.02)  LDD1526  [12]
 LDCM0288  AC28 HEK-293T C517(0.98)  LDD1527  [12]
 LDCM0289  AC29 HEK-293T C517(0.96)  LDD1528  [12]
 LDCM0290  AC3 HEK-293T C517(1.04)  LDD1529  [12]
 LDCM0291  AC30 HEK-293T C517(1.09)  LDD1530  [12]
 LDCM0292  AC31 HEK-293T C517(1.01)  LDD1531  [12]
 LDCM0293  AC32 HEK-293T C517(1.00)  LDD1532  [12]
 LDCM0294  AC33 HEK-293T C517(0.90)  LDD1533  [12]
 LDCM0295  AC34 HEK-293T C517(0.96)  LDD1534  [12]
 LDCM0296  AC35 HEK-293T C517(1.07)  LDD1535  [12]
 LDCM0297  AC36 HEK-293T C517(1.03)  LDD1536  [12]
 LDCM0298  AC37 HEK-293T C517(1.15)  LDD1537  [12]
 LDCM0299  AC38 HEK-293T C517(1.06)  LDD1538  [12]
 LDCM0300  AC39 HEK-293T C517(1.00)  LDD1539  [12]
 LDCM0301  AC4 HEK-293T C517(1.01)  LDD1540  [12]
 LDCM0302  AC40 HEK-293T C517(1.02)  LDD1541  [12]
 LDCM0303  AC41 HEK-293T C517(1.01)  LDD1542  [12]
 LDCM0304  AC42 HEK-293T C517(0.97)  LDD1543  [12]
 LDCM0305  AC43 HEK-293T C517(1.05)  LDD1544  [12]
 LDCM0306  AC44 HEK-293T C517(1.05)  LDD1545  [12]
 LDCM0307  AC45 HEK-293T C517(1.08)  LDD1546  [12]
 LDCM0308  AC46 HEK-293T C517(0.97)  LDD1547  [12]
 LDCM0309  AC47 HEK-293T C517(1.01)  LDD1548  [12]
 LDCM0310  AC48 HEK-293T C517(1.06)  LDD1549  [12]
 LDCM0311  AC49 HEK-293T C517(0.94)  LDD1550  [12]
 LDCM0312  AC5 HEK-293T C517(1.18)  LDD1551  [12]
 LDCM0313  AC50 HEK-293T C517(1.01)  LDD1552  [12]
 LDCM0314  AC51 HEK-293T C517(1.01)  LDD1553  [12]
 LDCM0315  AC52 HEK-293T C517(1.04)  LDD1554  [12]
 LDCM0316  AC53 HEK-293T C517(1.05)  LDD1555  [12]
 LDCM0317  AC54 HEK-293T C517(1.02)  LDD1556  [12]
 LDCM0318  AC55 HEK-293T C517(1.01)  LDD1557  [12]
 LDCM0319  AC56 HEK-293T C517(1.01)  LDD1558  [12]
 LDCM0320  AC57 HEK-293T C517(0.91)  LDD1559  [12]
 LDCM0321  AC58 HEK-293T C517(0.98)  LDD1560  [12]
 LDCM0322  AC59 HEK-293T C517(1.06)  LDD1561  [12]
 LDCM0323  AC6 HEK-293T C517(1.07)  LDD1562  [12]
 LDCM0324  AC60 HEK-293T C517(1.01)  LDD1563  [12]
 LDCM0325  AC61 HEK-293T C517(1.08)  LDD1564  [12]
 LDCM0326  AC62 HEK-293T C517(0.99)  LDD1565  [12]
 LDCM0327  AC63 HEK-293T C517(1.02)  LDD1566  [12]
 LDCM0328  AC64 HEK-293T C517(1.02)  LDD1567  [12]
 LDCM0334  AC7 HEK-293T C517(0.98)  LDD1568  [12]
 LDCM0345  AC8 HEK-293T C517(1.04)  LDD1569  [12]
 LDCM0248  AKOS034007472 HEK-293T C517(1.17)  LDD1511  [12]
 LDCM0356  AKOS034007680 HEK-293T C517(1.03)  LDD1570  [12]
 LDCM0275  AKOS034007705 HEK-293T C517(1.01)  LDD1514  [12]
 LDCM0156  Aniline NCI-H1299 11.34  LDD0403  [1]
 LDCM0367  CL1 HEK-293T C517(1.10)  LDD1571  [12]
 LDCM0368  CL10 HEK-293T C517(0.94)  LDD1572  [12]
 LDCM0369  CL100 HEK-293T C517(0.99)  LDD1573  [12]
 LDCM0370  CL101 HEK-293T C517(0.98)  LDD1574  [12]
 LDCM0371  CL102 HEK-293T C517(0.96)  LDD1575  [12]
 LDCM0372  CL103 HEK-293T C517(0.98)  LDD1576  [12]
 LDCM0373  CL104 HEK-293T C517(1.06)  LDD1577  [12]
 LDCM0374  CL105 HEK-293T C517(0.96)  LDD1578  [12]
 LDCM0375  CL106 HEK-293T C517(0.96)  LDD1579  [12]
 LDCM0376  CL107 HEK-293T C517(0.99)  LDD1580  [12]
 LDCM0377  CL108 HEK-293T C517(1.08)  LDD1581  [12]
 LDCM0378  CL109 HEK-293T C517(0.99)  LDD1582  [12]
 LDCM0379  CL11 HEK-293T C517(0.99)  LDD1583  [12]
 LDCM0380  CL110 HEK-293T C517(1.05)  LDD1584  [12]
 LDCM0381  CL111 HEK-293T C517(0.98)  LDD1585  [12]
 LDCM0382  CL112 HEK-293T C517(1.01)  LDD1586  [12]
 LDCM0383  CL113 HEK-293T C517(1.10)  LDD1587  [12]
 LDCM0384  CL114 HEK-293T C517(0.92)  LDD1588  [12]
 LDCM0385  CL115 HEK-293T C517(0.99)  LDD1589  [12]
 LDCM0386  CL116 HEK-293T C517(1.03)  LDD1590  [12]
 LDCM0387  CL117 HEK-293T C517(0.99)  LDD1591  [12]
 LDCM0388  CL118 HEK-293T C517(0.98)  LDD1592  [12]
 LDCM0389  CL119 HEK-293T C517(1.00)  LDD1593  [12]
 LDCM0390  CL12 HEK-293T C517(1.08)  LDD1594  [12]
 LDCM0391  CL120 HEK-293T C517(0.96)  LDD1595  [12]
 LDCM0392  CL121 HEK-293T C517(1.05)  LDD1596  [12]
 LDCM0393  CL122 HEK-293T C517(1.00)  LDD1597  [12]
 LDCM0394  CL123 HEK-293T C517(0.90)  LDD1598  [12]
 LDCM0395  CL124 HEK-293T C517(0.96)  LDD1599  [12]
 LDCM0396  CL125 HEK-293T C517(0.98)  LDD1600  [12]
 LDCM0397  CL126 HEK-293T C517(0.99)  LDD1601  [12]
 LDCM0398  CL127 HEK-293T C517(0.96)  LDD1602  [12]
 LDCM0399  CL128 HEK-293T C517(1.06)  LDD1603  [12]
 LDCM0400  CL13 HEK-293T C517(1.10)  LDD1604  [12]
 LDCM0401  CL14 HEK-293T C517(1.06)  LDD1605  [12]
 LDCM0402  CL15 HEK-293T C517(0.93)  LDD1606  [12]
 LDCM0403  CL16 HEK-293T C517(1.00)  LDD1607  [12]
 LDCM0404  CL17 HEK-293T C517(0.98)  LDD1608  [12]
 LDCM0405  CL18 HEK-293T C517(0.98)  LDD1609  [12]
 LDCM0406  CL19 HEK-293T C517(0.98)  LDD1610  [12]
 LDCM0407  CL2 HEK-293T C517(1.07)  LDD1611  [12]
 LDCM0408  CL20 HEK-293T C517(1.04)  LDD1612  [12]
 LDCM0409  CL21 HEK-293T C517(1.16)  LDD1613  [12]
 LDCM0410  CL22 HEK-293T C517(1.07)  LDD1614  [12]
 LDCM0411  CL23 HEK-293T C517(1.12)  LDD1615  [12]
 LDCM0412  CL24 HEK-293T C517(1.08)  LDD1616  [12]
 LDCM0413  CL25 HEK-293T C517(0.94)  LDD1617  [12]
 LDCM0414  CL26 HEK-293T C517(1.02)  LDD1618  [12]
 LDCM0415  CL27 HEK-293T C517(1.03)  LDD1619  [12]
 LDCM0416  CL28 HEK-293T C517(1.04)  LDD1620  [12]
 LDCM0417  CL29 HEK-293T C517(0.94)  LDD1621  [12]
 LDCM0418  CL3 HEK-293T C517(0.96)  LDD1622  [12]
 LDCM0419  CL30 HEK-293T C517(1.05)  LDD1623  [12]
 LDCM0420  CL31 HEK-293T C517(1.06)  LDD1624  [12]
 LDCM0421  CL32 HEK-293T C517(1.03)  LDD1625  [12]
 LDCM0422  CL33 HEK-293T C517(1.17)  LDD1626  [12]
 LDCM0423  CL34 HEK-293T C517(1.14)  LDD1627  [12]
 LDCM0424  CL35 HEK-293T C517(1.08)  LDD1628  [12]
 LDCM0425  CL36 HEK-293T C517(0.97)  LDD1629  [12]
 LDCM0426  CL37 HEK-293T C517(1.00)  LDD1630  [12]
 LDCM0428  CL39 HEK-293T C517(1.01)  LDD1632  [12]
 LDCM0429  CL4 HEK-293T C517(1.05)  LDD1633  [12]
 LDCM0430  CL40 HEK-293T C517(1.04)  LDD1634  [12]
 LDCM0431  CL41 HEK-293T C517(0.89)  LDD1635  [12]
 LDCM0432  CL42 HEK-293T C517(0.92)  LDD1636  [12]
 LDCM0433  CL43 HEK-293T C517(1.02)  LDD1637  [12]
 LDCM0434  CL44 HEK-293T C517(1.02)  LDD1638  [12]
 LDCM0435  CL45 HEK-293T C517(1.02)  LDD1639  [12]
 LDCM0436  CL46 HEK-293T C517(1.10)  LDD1640  [12]
 LDCM0437  CL47 HEK-293T C517(1.09)  LDD1641  [12]
 LDCM0438  CL48 HEK-293T C517(1.08)  LDD1642  [12]
 LDCM0439  CL49 HEK-293T C517(1.20)  LDD1643  [12]
 LDCM0440  CL5 HEK-293T C517(1.05)  LDD1644  [12]
 LDCM0441  CL50 HEK-293T C517(1.02)  LDD1645  [12]
 LDCM0443  CL52 HEK-293T C517(1.12)  LDD1646  [12]
 LDCM0444  CL53 HEK-293T C517(0.96)  LDD1647  [12]
 LDCM0445  CL54 HEK-293T C517(1.02)  LDD1648  [12]
 LDCM0446  CL55 HEK-293T C517(1.16)  LDD1649  [12]
 LDCM0447  CL56 HEK-293T C517(1.07)  LDD1650  [12]
 LDCM0448  CL57 HEK-293T C517(0.99)  LDD1651  [12]
 LDCM0449  CL58 HEK-293T C517(1.01)  LDD1652  [12]
 LDCM0450  CL59 HEK-293T C517(1.03)  LDD1653  [12]
 LDCM0451  CL6 HEK-293T C517(0.97)  LDD1654  [12]
 LDCM0452  CL60 HEK-293T C517(1.15)  LDD1655  [12]
 LDCM0453  CL61 HEK-293T C517(0.98)  LDD1656  [12]
 LDCM0454  CL62 HEK-293T C517(1.06)  LDD1657  [12]
 LDCM0455  CL63 HEK-293T C517(0.92)  LDD1658  [12]
 LDCM0456  CL64 HEK-293T C517(0.94)  LDD1659  [12]
 LDCM0457  CL65 HEK-293T C517(0.92)  LDD1660  [12]
 LDCM0458  CL66 HEK-293T C517(1.08)  LDD1661  [12]
 LDCM0459  CL67 HEK-293T C517(1.08)  LDD1662  [12]
 LDCM0460  CL68 HEK-293T C517(0.92)  LDD1663  [12]
 LDCM0461  CL69 HEK-293T C517(1.18)  LDD1664  [12]
 LDCM0462  CL7 HEK-293T C517(1.07)  LDD1665  [12]
 LDCM0463  CL70 HEK-293T C517(1.13)  LDD1666  [12]
 LDCM0464  CL71 HEK-293T C517(1.07)  LDD1667  [12]
 LDCM0465  CL72 HEK-293T C517(1.11)  LDD1668  [12]
 LDCM0466  CL73 HEK-293T C517(1.06)  LDD1669  [12]
 LDCM0467  CL74 HEK-293T C517(1.07)  LDD1670  [12]
 LDCM0469  CL76 HEK-293T C517(1.04)  LDD1672  [12]
 LDCM0470  CL77 HEK-293T C517(0.96)  LDD1673  [12]
 LDCM0471  CL78 HEK-293T C517(1.01)  LDD1674  [12]
 LDCM0472  CL79 HEK-293T C517(1.05)  LDD1675  [12]
 LDCM0473  CL8 HEK-293T C517(1.01)  LDD1676  [12]
 LDCM0474  CL80 HEK-293T C517(1.07)  LDD1677  [12]
 LDCM0475  CL81 HEK-293T C517(1.08)  LDD1678  [12]
 LDCM0476  CL82 HEK-293T C517(1.11)  LDD1679  [12]
 LDCM0477  CL83 HEK-293T C517(1.12)  LDD1680  [12]
 LDCM0478  CL84 HEK-293T C517(1.08)  LDD1681  [12]
 LDCM0479  CL85 HEK-293T C517(1.06)  LDD1682  [12]
 LDCM0480  CL86 HEK-293T C517(1.06)  LDD1683  [12]
 LDCM0481  CL87 HEK-293T C517(1.04)  LDD1684  [12]
 LDCM0482  CL88 HEK-293T C517(1.06)  LDD1685  [12]
 LDCM0483  CL89 HEK-293T C517(1.09)  LDD1686  [12]
 LDCM0484  CL9 HEK-293T C517(1.30)  LDD1687  [12]
 LDCM0485  CL90 HEK-293T C517(0.99)  LDD1688  [12]
 LDCM0486  CL91 HEK-293T C517(1.07)  LDD1689  [12]
 LDCM0487  CL92 HEK-293T C517(1.06)  LDD1690  [12]
 LDCM0488  CL93 HEK-293T C517(0.99)  LDD1691  [12]
 LDCM0489  CL94 HEK-293T C517(0.98)  LDD1692  [12]
 LDCM0490  CL95 HEK-293T C517(0.94)  LDD1693  [12]
 LDCM0491  CL96 HEK-293T C517(1.07)  LDD1694  [12]
 LDCM0492  CL97 HEK-293T C517(1.01)  LDD1695  [12]
 LDCM0493  CL98 HEK-293T C517(1.03)  LDD1696  [12]
 LDCM0494  CL99 HEK-293T C517(0.92)  LDD1697  [12]
 LDCM0495  E2913 HEK-293T C517(1.04)  LDD1698  [12]
 LDCM0468  Fragment33 HEK-293T C517(0.94)  LDD1671  [12]
 LDCM0427  Fragment51 HEK-293T C517(1.01)  LDD1631  [12]
 LDCM0116  HHS-0101 DM93 Y509(1.50)  LDD0264  [6]
 LDCM0117  HHS-0201 DM93 Y509(0.74)  LDD0265  [6]
 LDCM0118  HHS-0301 DM93 Y509(0.97)  LDD0266  [6]
 LDCM0119  HHS-0401 DM93 Y509(0.77)  LDD0267  [6]
 LDCM0120  HHS-0701 DM93 Y509(1.39)  LDD0268  [6]
 LDCM0022  KB02 HEK-293T C517(1.03)  LDD1492  [12]
 LDCM0023  KB03 Jurkat C517(4.67)  LDD0209  [5]
 LDCM0024  KB05 G361 C573(2.16)  LDD3311  [13]
 LDCM0014  Panhematin HEK-293T 3.47  LDD0062  [4]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 12 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2) 5'-AMP-activated protein kinase beta subunit family O43741
Carbonic anhydrase-related protein (CA8) Alpha-carbonic anhydrase family P35219
Cell division cycle protein 23 homolog (CDC23) APC8/CDC23 family Q9UJX2
Probable ATP-dependent RNA helicase DDX6 (DDX6) DEAD box helicase family P26196
Glycerate kinase (GLYCTK) Glycerate kinase type-2 family Q8IVS8
Inactive glycosyltransferase 25 family member 3 (CERCAM) Glycosyltransferase 25 family Q5T4B2
General transcription and DNA repair factor IIH helicase subunit XPB (ERCC3) Helicase family P19447
Calpain-7 (CAPN7) Peptidase C2 family Q9Y6W3
MTRF1L release factor glutamine methyltransferase (HEMK1) Protein N5-glutamine methyltransferase family Q9Y5R4
E3 ubiquitin-protein ligase Praja-1 (PJA1) . Q8NG27
LON peptidase N-terminal domain and RING finger protein 1 (LONRF1) . Q17RB8
Probable E3 ubiquitin-protein ligase makorin-3 (MKRN3) . Q13064
Transporter and channel
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Importin subunit alpha-1 (KPNA2) Importin alpha family P52292
Importin subunit alpha-7 (KPNA6) Importin alpha family O60684
Glycine receptor subunit alpha-1 (GLRA1) Ligand-gated ion channel family P23415
MyoD family inhibitor (MDFI) MDFI family Q99750
Transcription factor
Click To Hide/Show 18 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein Hox-C9 (HOXC9) Abd-B homeobox family P31274
Doublesex- and mab-3-related transcription factor 2 (DMRT2) DMRT family Q9Y5R5
Zinc finger protein ZIC 1 (ZIC1) GLI C2H2-type zinc-finger protein family Q15915
Homeobox protein prophet of Pit-1 (PROP1) Paired homeobox family O75360
Pituitary homeobox 1 (PITX1) Paired homeobox family P78337
Rhox homeobox family member 2 (RHOXF2) Paired-like homeobox family Q9BQY4
PHD finger protein 1 (PHF1) Polycomblike family O43189
AT-rich interactive domain-containing protein 5A (ARID5A) . Q03989
Class E basic helix-loop-helix protein 40 (BHLHE40) . O14503
Forkhead box protein D2 (FOXD2) . O60548
Forkhead box protein H1 (FOXH1) . O75593
Homeobox protein MOX-2 (MEOX2) . P50222
Homeobox protein notochord (NOTO) . A8MTQ0
Homeobox protein VENTX (VENTX) . O95231
T-box transcription factor TBX6 (TBX6) . O95947
T-cell leukemia homeobox protein 3 (TLX3) . O43711
Transcription factor GATA-5 (GATA5) . Q9BWX5
Transcription factor SOX-10 (SOX10) . P56693
Other
Click To Hide/Show 42 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cilia- and flagella-associated protein 206 (CFAP206) CFAP206 family Q8IYR0
Eukaryotic translation initiation factor 4E type 2 (EIF4E2) Eukaryotic initiation factor 4E family O60573
Protein FAM83A (FAM83A) FAM83 family Q86UY5
Keratin-associated protein 19-5 (KRTAP19-5) KRTAP type 19 family Q3LI72
Keratin-associated protein 6-1 (KRTAP6-1) KRTAP type 6 family Q3LI64
Zinc finger protein 488 (ZNF488) Krueppel C2H2-type zinc-finger protein family Q96MN9
MAPK-interacting and spindle-stabilizing protein-like (MAPK1IP1L) MISS family Q8NDC0
H/ACA ribonucleoprotein complex non-core subunit NAF1 (NAF1) NAF1 family Q96HR8
Paraneoplastic antigen-like protein 5 (PNMA5) PNMA family Q96PV4
Proline-rich protein 20D (PRR20D) PRR20 family P86480
RNA guanine-N7 methyltransferase activating subunit (RAMAC) RAM family Q9BTL3
Survival motor neuron protein (SMN1; SMN2) SMN family Q16637
Probable RNA-binding protein 23 (RBM23) Splicing factor SR family Q86U06
U1 small nuclear ribonucleoprotein C (SNRPC) U1 small nuclear ribonucleoprotein C family P09234
YTH domain-containing family protein 1 (YTHDF1) YTHDF family Q9BYJ9
AP-4 complex accessory subunit RUSC1 (RUSC1) . Q9BVN2
BAG family molecular chaperone regulator 3 (BAG3) . O95817
BAG family molecular chaperone regulator 4 (BAG4) . O95429
Calcium homeostasis endoplasmic reticulum protein (CHERP) . Q8IWX8
CD2 antigen cytoplasmic tail-binding protein 2 (CD2BP2) . O95400
Coiled-coil domain-containing protein 120 (CCDC120) . Q96HB5
DAZ-associated protein 2 (DAZAP2) . Q15038
Disabled homolog 1 (DAB1) . O75553
G patch domain and ankyrin repeat-containing protein 1 (GPANK1) . O95872
Heat shock factor 2-binding protein (HSF2BP) . O75031
Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) . O14964
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) . P31943
La-related protein 4B (LARP4B) . Q92615
Leukocyte receptor cluster member 8 (LENG8) . Q96PV6
Melanoma-associated antigen D1 (MAGED1) . Q9Y5V3
Proline-rich protein 35 (PRR35) . P0CG20
Protein TFG (TFG) . Q92734
Rho guanine nucleotide exchange factor 16 (ARHGEF16) . Q5VV41
RNA binding protein fox-1 homolog 2 (RBFOX2) . O43251
RNA-binding protein with multiple splicing (RBPMS) . Q93062
RNA-binding protein with multiple splicing 2 (RBPMS2) . Q6ZRY4
Stromal membrane-associated protein 2 (SMAP2) . Q8WU79
Testis-specific protein 10-interacting protein (TSGA10IP) . Q3SY00
Tetratricopeptide repeat protein 23 (TTC23) . Q5W5X9
Tetratricopeptide repeat protein 32 (TTC32) . Q5I0X7
Ubiquilin-2 (UBQLN2) . Q9UHD9
Uncharacterized protein C1orf94 (C1orf94) . Q6P1W5

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
3 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
4 A Chemical Proteomic Map of Heme-Protein Interactions. J Am Chem Soc. 2022 Aug 24;144(33):15013-15019. doi: 10.1021/jacs.2c06104. Epub 2022 Aug 12.
Mass spectrometry data entry: PXD034651
5 Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.
6 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
7 Global targeting of functional tyrosines using sulfur-triazole exchange chemistry. Nat Chem Biol. 2020 Feb;16(2):150-159. doi: 10.1038/s41589-019-0404-5. Epub 2019 Nov 25.
8 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
9 Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows. bioRxiv [Preprint]. 2023 Feb 18:2023.02.17.529022. doi: 10.1101/2023.02.17.529022.
Mass spectrometry data entry: PXD039931
10 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
11 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
12 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
13 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840