Details of the Target

General Information of Target

Target ID LDTP11325
Target Name Sodium channel modifier 1 (SCNM1)
Gene Name SCNM1
Gene ID 100534012
Synonyms
Sodium channel modifier 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL
HGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHMER
AEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPIDRS
GRVADLTEQYNEQYGAVRTPYTMSYGDSLYYNNAYGALDAYYKRCRAARSYEAVAAAAAS
VYNYAEQTLSQLPQVQNTAMASHLTSTSLDPYDRHLLPTSGAAATAAAAAAAAAAVTAAS
TSYYGRDRSPLRRATAPVPTVGEGYGYGHESELSQASAAARNSLYDMARYEREQYADRAR
YSAF
Target Bioclass
Transporter and channel
Subcellular location
Nucleus, nucleoplasm
Function As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. Plays a role in the regulation of primary cilia length and Hedgehog signaling.
Uniprot ID
Q9BWG6
Ensemble ID
ENST00000368902.1
HGNC ID
HGNC:23136

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
HPAP
 Probe Info  		4.11  LDD0062  [1]
IA-alkyne
 Probe Info  		C127(2.70)  LDD0372  [2]
DBIA
 Probe Info  		C127(1.11); C128(1.11)  LDD0078  [3]
Phosphinate-6
 Probe Info  		C127(0.00); C128(0.00)  LDD0018  [4]
AOyne
 Probe Info  		15.00  LDD0443  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0026  4SU-RNA+native RNA HEK-293T C127(2.70)  LDD0372  [2]
 LDCM0215  AC10 HEK-293T C127(0.82); C128(0.82)  LDD0813  [3]
 LDCM0216  AC100 HEK-293T C127(0.93); C128(0.93)  LDD0814  [3]
 LDCM0217  AC101 HEK-293T C127(0.78); C128(0.78)  LDD0815  [3]
 LDCM0218  AC102 HEK-293T C127(0.89); C128(0.89)  LDD0816  [3]
 LDCM0219  AC103 HEK-293T C127(0.83); C128(0.83)  LDD0817  [3]
 LDCM0220  AC104 HEK-293T C127(0.76); C128(0.76)  LDD0818  [3]
 LDCM0221  AC105 HEK-293T C127(0.99); C128(0.99)  LDD0819  [3]
 LDCM0222  AC106 HEK-293T C127(0.94); C128(0.94)  LDD0820  [3]
 LDCM0223  AC107 HEK-293T C127(0.97); C128(0.97)  LDD0821  [3]
 LDCM0224  AC108 HEK-293T C127(0.83); C128(0.83)  LDD0822  [3]
 LDCM0225  AC109 HEK-293T C127(0.87); C128(0.87)  LDD0823  [3]
 LDCM0226  AC11 HEK-293T C127(1.05); C128(1.05)  LDD0824  [3]
 LDCM0227  AC110 HEK-293T C127(0.96); C128(0.96)  LDD0825  [3]
 LDCM0228  AC111 HEK-293T C127(0.82); C128(0.82)  LDD0826  [3]
 LDCM0229  AC112 HEK-293T C127(0.94); C128(0.94)  LDD0827  [3]
 LDCM0237  AC12 HEK-293T C127(0.82); C128(0.82)  LDD0835  [3]
 LDCM0259  AC14 HEK-293T C127(0.95); C128(0.95)  LDD0857  [3]
 LDCM0270  AC15 HEK-293T C127(1.03); C128(1.03)  LDD0868  [3]
 LDCM0277  AC18 HEK-293T C127(1.24)  LDD1516  [6]
 LDCM0279  AC2 HEK-293T C127(0.80)  LDD1518  [6]
 LDCM0285  AC25 HEK-293T C127(0.93); C128(0.93)  LDD0883  [3]
 LDCM0286  AC26 HEK-293T C127(0.87); C128(0.87)  LDD0884  [3]
 LDCM0287  AC27 HEK-293T C127(1.08); C128(1.08)  LDD0885  [3]
 LDCM0288  AC28 HEK-293T C127(0.93); C128(0.93)  LDD0886  [3]
 LDCM0289  AC29 HEK-293T C127(0.98); C128(0.98)  LDD0887  [3]
 LDCM0291  AC30 HEK-293T C127(1.02); C128(1.02)  LDD0889  [3]
 LDCM0292  AC31 HEK-293T C127(1.05); C128(1.05)  LDD0890  [3]
 LDCM0293  AC32 HEK-293T C127(1.14); C128(1.14)  LDD0891  [3]
 LDCM0294  AC33 HEK-293T C127(0.99); C128(0.99)  LDD0892  [3]
 LDCM0295  AC34 HEK-293T C127(1.10); C128(1.10)  LDD0893  [3]
 LDCM0296  AC35 HEK-293T C127(0.88); C128(0.88)  LDD0894  [3]
 LDCM0297  AC36 HEK-293T C127(0.84); C128(0.84)  LDD0895  [3]
 LDCM0298  AC37 HEK-293T C127(0.81); C128(0.81)  LDD0896  [3]
 LDCM0299  AC38 HEK-293T C127(1.07); C128(1.07)  LDD0897  [3]
 LDCM0300  AC39 HEK-293T C127(1.17); C128(1.17)  LDD0898  [3]
 LDCM0302  AC40 HEK-293T C127(0.90); C128(0.90)  LDD0900  [3]
 LDCM0303  AC41 HEK-293T C127(0.96); C128(0.96)  LDD0901  [3]
 LDCM0304  AC42 HEK-293T C127(0.82); C128(0.82)  LDD0902  [3]
 LDCM0305  AC43 HEK-293T C127(0.87); C128(0.87)  LDD0903  [3]
 LDCM0306  AC44 HEK-293T C127(0.96); C128(0.96)  LDD0904  [3]
 LDCM0307  AC45 HEK-293T C127(0.85); C128(0.85)  LDD0905  [3]
 LDCM0308  AC46 HEK-293T C127(0.97); C128(0.97)  LDD0906  [3]
 LDCM0309  AC47 HEK-293T C127(0.93); C128(0.93)  LDD0907  [3]
 LDCM0310  AC48 HEK-293T C127(0.92); C128(0.92)  LDD0908  [3]
 LDCM0311  AC49 HEK-293T C127(1.02); C128(1.02)  LDD0909  [3]
 LDCM0313  AC50 HEK-293T C127(0.99); C128(0.99)  LDD0911  [3]
 LDCM0314  AC51 HEK-293T C127(1.20); C128(1.20)  LDD0912  [3]
 LDCM0315  AC52 HEK-293T C127(1.20); C128(1.20)  LDD0913  [3]
 LDCM0316  AC53 HEK-293T C127(0.97); C128(0.97)  LDD0914  [3]
 LDCM0317  AC54 HEK-293T C127(1.26); C128(1.26)  LDD0915  [3]
 LDCM0318  AC55 HEK-293T C127(1.18); C128(1.18)  LDD0916  [3]
 LDCM0319  AC56 HEK-293T C127(0.92); C128(0.92)  LDD0917  [3]
 LDCM0321  AC58 HEK-293T C127(0.87)  LDD1560  [6]
 LDCM0323  AC6 HEK-293T C127(0.87); C128(0.87)  LDD0921  [3]
 LDCM0334  AC7 HEK-293T C127(0.87); C128(0.87)  LDD0932  [3]
 LDCM0345  AC8 HEK-293T C127(0.98); C128(0.98)  LDD0943  [3]
 LDCM0365  AC98 HEK-293T C127(0.90); C128(0.90)  LDD0963  [3]
 LDCM0366  AC99 HEK-293T C127(0.82); C128(0.82)  LDD0964  [3]
 LDCM0248  AKOS034007472 HEK-293T C127(1.26); C128(1.26)  LDD0846  [3]
 LDCM0356  AKOS034007680 HEK-293T C127(0.88); C128(0.88)  LDD0954  [3]
 LDCM0275  AKOS034007705 HEK-293T C127(1.30); C128(1.30)  LDD0873  [3]
 LDCM0020  ARS-1620 HCC44 C127(1.11); C128(1.11)  LDD0078  [3]
 LDCM0370  CL101 HEK-293T C127(1.13); C128(1.13)  LDD0968  [3]
 LDCM0371  CL102 HEK-293T C127(1.44); C128(1.44)  LDD0969  [3]
 LDCM0372  CL103 HEK-293T C127(0.97); C128(0.97)  LDD0970  [3]
 LDCM0373  CL104 HEK-293T C127(0.90); C128(0.90)  LDD0971  [3]
 LDCM0382  CL112 HEK-293T C127(1.14); C128(1.14)  LDD0980  [3]
 LDCM0383  CL113 HEK-293T C127(1.00); C128(1.00)  LDD0981  [3]
 LDCM0384  CL114 HEK-293T C127(1.16); C128(1.16)  LDD0982  [3]
 LDCM0385  CL115 HEK-293T C127(1.14); C128(1.14)  LDD0983  [3]
 LDCM0386  CL116 HEK-293T C127(1.13); C128(1.13)  LDD0984  [3]
 LDCM0387  CL117 HEK-293T C127(1.05); C128(1.05)  LDD0985  [3]
 LDCM0388  CL118 HEK-293T C127(1.04); C128(1.04)  LDD0986  [3]
 LDCM0389  CL119 HEK-293T C127(0.80); C128(0.80)  LDD0987  [3]
 LDCM0391  CL120 HEK-293T C127(0.96); C128(0.96)  LDD0989  [3]
 LDCM0392  CL121 HEK-293T C127(0.92); C128(0.92)  LDD0990  [3]
 LDCM0393  CL122 HEK-293T C127(1.18); C128(1.18)  LDD0991  [3]
 LDCM0394  CL123 HEK-293T C127(0.98); C128(0.98)  LDD0992  [3]
 LDCM0395  CL124 HEK-293T C127(1.28); C128(1.28)  LDD0993  [3]
 LDCM0405  CL18 HEK-293T C127(1.16)  LDD1609  [6]
 LDCM0419  CL30 HEK-293T C127(0.73)  LDD1623  [6]
 LDCM0432  CL42 HEK-293T C127(0.86)  LDD1636  [6]
 LDCM0436  CL46 HEK-293T C127(0.93); C128(0.93)  LDD1034  [3]
 LDCM0437  CL47 HEK-293T C127(1.11); C128(1.11)  LDD1035  [3]
 LDCM0438  CL48 HEK-293T C127(1.53); C128(1.53)  LDD1036  [3]
 LDCM0439  CL49 HEK-293T C127(0.98); C128(0.98)  LDD1037  [3]
 LDCM0441  CL50 HEK-293T C127(1.12); C128(1.12)  LDD1039  [3]
 LDCM0442  CL51 HEK-293T C127(1.37); C128(1.37)  LDD1040  [3]
 LDCM0443  CL52 HEK-293T C127(1.05); C128(1.05)  LDD1041  [3]
 LDCM0444  CL53 HEK-293T C127(1.36); C128(1.36)  LDD1042  [3]
 LDCM0445  CL54 HEK-293T C127(1.00); C128(1.00)  LDD1043  [3]
 LDCM0446  CL55 HEK-293T C127(0.77); C128(0.77)  LDD1044  [3]
 LDCM0447  CL56 HEK-293T C127(1.25); C128(1.25)  LDD1045  [3]
 LDCM0448  CL57 HEK-293T C127(1.63); C128(1.63)  LDD1046  [3]
 LDCM0449  CL58 HEK-293T C127(1.14); C128(1.14)  LDD1047  [3]
 LDCM0450  CL59 HEK-293T C127(1.09); C128(1.09)  LDD1048  [3]
 LDCM0451  CL6 HEK-293T C127(0.75)  LDD1654  [6]
 LDCM0452  CL60 HEK-293T C127(1.60); C128(1.60)  LDD1050  [3]
 LDCM0458  CL66 HEK-293T C127(0.97)  LDD1661  [6]
 LDCM0469  CL76 HEK-293T C127(0.95); C128(0.95)  LDD1067  [3]
 LDCM0470  CL77 HEK-293T C127(0.98); C128(0.98)  LDD1068  [3]
 LDCM0471  CL78 HEK-293T C127(0.84); C128(0.84)  LDD1069  [3]
 LDCM0472  CL79 HEK-293T C127(1.01); C128(1.01)  LDD1070  [3]
 LDCM0474  CL80 HEK-293T C127(0.97); C128(0.97)  LDD1072  [3]
 LDCM0475  CL81 HEK-293T C127(1.01); C128(1.01)  LDD1073  [3]
 LDCM0476  CL82 HEK-293T C127(0.77); C128(0.77)  LDD1074  [3]
 LDCM0477  CL83 HEK-293T C127(0.79); C128(0.79)  LDD1075  [3]
 LDCM0478  CL84 HEK-293T C127(0.88); C128(0.88)  LDD1076  [3]
 LDCM0479  CL85 HEK-293T C127(0.88); C128(0.88)  LDD1077  [3]
 LDCM0480  CL86 HEK-293T C127(0.82); C128(0.82)  LDD1078  [3]
 LDCM0481  CL87 HEK-293T C127(1.20); C128(1.20)  LDD1079  [3]
 LDCM0482  CL88 HEK-293T C127(1.31); C128(1.31)  LDD1080  [3]
 LDCM0483  CL89 HEK-293T C127(1.02); C128(1.02)  LDD1081  [3]
 LDCM0485  CL90 HEK-293T C127(0.93); C128(0.93)  LDD1083  [3]
 LDCM0573  Fragment11 Ramos 20.00  LDD2190  [7]
 LDCM0574  Fragment12 Ramos 0.81  LDD2191  [7]
 LDCM0575  Fragment13 Ramos 0.91  LDD2192  [7]
 LDCM0576  Fragment14 Ramos 0.57  LDD2193  [7]
 LDCM0579  Fragment20 Ramos 1.04  LDD2194  [7]
 LDCM0580  Fragment21 Ramos 1.00  LDD2195  [7]
 LDCM0578  Fragment27 Ramos 0.92  LDD2197  [7]
 LDCM0588  Fragment30 Ramos 1.26  LDD2199  [7]
 LDCM0589  Fragment31 Ramos 1.43  LDD2200  [7]
 LDCM0468  Fragment33 Ramos 2.61  LDD2202  [7]
 LDCM0596  Fragment38 Ramos 1.84  LDD2203  [7]
 LDCM0014  Panhematin HEK-293T 4.11  LDD0062  [1]
 LDCM0021  THZ1 HCT 116 C127(1.24); C128(1.24)  LDD2173  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 19 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
PR domain zinc finger protein 14 (PRDM14) Class V-like SAM-binding methyltransferase superfamily Q9GZV8
NADH dehydrogenase 1 beta subcomplex subunit 7 (NDUFB7) Complex I NDUFB7 subunit family P17568
Phospholipid scramblase 1 (PLSCR1) Phospholipid scramblase family O15162
Tribbles homolog 3 (TRIB3) CAMK Ser/Thr protein kinase family Q96RU7
E3 ubiquitin-protein ligase TRIM23 (TRIM23) Arf family P36406
Rho-related GTP-binding protein RhoH (RHOH) Rho family Q15669
TNF receptor-associated factor 2 (TRAF2) TNF receptor-associated factor family Q12933
Unconventional myosin-If (MYO1F) Myosin family O00160
E3 ubiquitin-protein ligase TRIM37 (TRIM37) TRIM/RBCC family O94972
Tripartite motif-containing protein 42 (TRIM42) TRIM/RBCC family Q8IWZ5
Zinc finger protein RFP (TRIM27) TRIM/RBCC family P14373
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1) . Q9GZU7
E3 ubiquitin-protein ligase FANCL (FANCL) . Q9NW38
E3 ubiquitin-protein ligase LNX (LNX1) . Q8TBB1
E3 ubiquitin-protein ligase MYLIP (MYLIP) . Q8WY64
Fibronectin type III and SPRY domain-containing protein 2 (FSD2) . A1L4K1
pre-mRNA splicing regulator USH1G (USH1G) . Q495M9
Probable E3 ubiquitin-protein ligase makorin-3 (MKRN3) . Q13064
Tripartite motif-containing protein 54 (TRIM54) . Q9BYV2
Transporter and channel
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Leucine zipper putative tumor suppressor 1 (LZTS1) LZTS family Q9Y250
MyoD family inhibitor (MDFI) MDFI family Q99750
Syntaxin-19 (STX19) Syntaxin family Q8N4C7
Transcription factor
Click To Hide/Show 28 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Transcription regulator protein BACH2 (BACH2) BZIP family Q9BYV9
G protein-coupled receptor associated sorting protein 3 (GPRASP3) GPRASP family Q6PI77
DNA-binding protein Ikaros (IKZF1) Ikaros C2H2-type zinc-finger protein family Q13422
Zinc finger protein Aiolos (IKZF3) Ikaros C2H2-type zinc-finger protein family Q9UKT9
RB-associated KRAB zinc finger protein (RBAK) Krueppel C2H2-type zinc-finger protein family Q9NYW8
Zinc finger and BTB domain-containing protein 14 (ZBTB14) Krueppel C2H2-type zinc-finger protein family O43829
Zinc finger imprinted 2 (ZIM2) Krueppel C2H2-type zinc-finger protein family Q9NZV7
Zinc finger protein 135 (ZNF135) Krueppel C2H2-type zinc-finger protein family P52742
Zinc finger protein 19 (ZNF19) Krueppel C2H2-type zinc-finger protein family P17023
Zinc finger protein 20 (ZNF20) Krueppel C2H2-type zinc-finger protein family P17024
Zinc finger protein 438 (ZNF438) Krueppel C2H2-type zinc-finger protein family Q7Z4V0
Zinc finger protein 511 (ZNF511) Krueppel C2H2-type zinc-finger protein family Q8NB15
Zinc finger protein 526 (ZNF526) Krueppel C2H2-type zinc-finger protein family Q8TF50
Zinc finger protein 547 (ZNF547) Krueppel C2H2-type zinc-finger protein family Q8IVP9
Zinc finger protein 552 (ZNF552) Krueppel C2H2-type zinc-finger protein family Q9H707
Zinc finger protein 688 (ZNF688) Krueppel C2H2-type zinc-finger protein family P0C7X2
Zinc finger protein 76 (ZNF76) Krueppel C2H2-type zinc-finger protein family P36508
Zinc finger protein 774 (ZNF774) Krueppel C2H2-type zinc-finger protein family Q6NX45
NF-kappa-B inhibitor delta (NFKBID) NF-kappa-B inhibitor family Q8NI38
Krueppel-like factor 15 (KLF15) Sp1 C2H2-type zinc-finger protein family Q9UIH9
Pre-B-cell leukemia transcription factor 4 (PBX4) TALE/PBX homeobox family Q9BYU1
Golgin-45 (BLZF1) . Q9H2G9
High mobility group protein 20A (HMG20A) . Q9NP66
Homeobox protein MOX-2 (MEOX2) . P50222
Homeobox-containing protein 1 (HMBOX1) . Q6NT76
LIM/homeobox protein Lhx1 (LHX1) . P48742
Zinc finger and BTB domain-containing protein 1 (ZBTB1) . Q9Y2K1
Zinc finger protein 202 (ZNF202) . O95125
Other
Click To Hide/Show 96 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Afadin- and alpha-actinin-binding protein (SSX2IP) ADIP family Q9Y2D8
Large ribosomal subunit protein bL28m (MRPL28) Bacterial ribosomal protein bL28 family Q13084
Calcium-binding and coiled-coil domain-containing protein 2 (CALCOCO2) CALCOCO family Q13137
Neutrophil gelatinase-associated lipocalin (LCN2) Lipocalin family P80188
Cerebellar degeneration-related protein 2 (CDR2) CDR2 family Q01850
Cerebellar degeneration-related protein 2-like (CDR2L) CDR2 family Q86X02
Centrosomal protein of 76 kDa (CEP76) CEP76 family Q8TAP6
Protein chibby homolog 2 (CBY2) Chibby family Q8NA61
Cysteine-rich hydrophobic domain-containing protein 2 (CHIC2) CHIC family Q9UKJ5
Conserved oligomeric Golgi complex subunit 6 (COG6) COG6 family Q9Y2V7
Cysteine-rich tail protein 1 (CYSRT1) CYSRT1 family A8MQ03
Dynein regulatory complex subunit 4 (GAS8) DRC4 family O95995
Protein FAM161A (FAM161A) FAM161 family Q3B820
Protein FAM228A (FAM228A) FAM228 family Q86W67
GRB10-interacting GYF protein 1 (GIGYF1) GIGYF family O75420
Golgin subfamily A member 2 (GOLGA2) GOLGA2 family Q08379
Golgin subfamily A member 6-like protein 9 (GOLGA6L9) GOLGA6 family A6NEM1
Homer protein homolog 3 (HOMER3) Homer family Q9NSC5
Protein INCA1 (INCA1) INCA family Q0VD86
Keratin, type I cuticular Ha1 (KRT31) Intermediate filament family Q15323
Keratin, type I cuticular Ha3-II (KRT33B) Intermediate filament family Q14525
Keratin, type I cuticular Ha4 (KRT34) Intermediate filament family O76011
Keratin, type I cuticular Ha5 (KRT35) Intermediate filament family Q92764
Keratin, type I cuticular Ha8 (KRT38) Intermediate filament family O76015
Keratin, type I cytoskeletal 27 (KRT27) Intermediate filament family Q7Z3Y8
Keratin, type I cytoskeletal 39 (KRT39) Intermediate filament family Q6A163
Keratin, type II cytoskeletal 75 (KRT75) Intermediate filament family O95678
Vimentin (VIM) Intermediate filament family P08670
Interleukin-1 receptor-associated kinase 1-binding protein 1 (IRAK1BP1) IRAK1BP1 family Q5VVH5
Janus kinase and microtubule-interacting protein 1 (JAKMIP1) JAKMIP family Q96N16
Keratin-associated protein 1-1 (KRTAP1-1) KRTAP type 1 family Q07627
Keratin-associated protein 10-5 (KRTAP10-5) KRTAP type 10 family P60370
Keratin-associated protein 10-7 (KRTAP10-7) KRTAP type 10 family P60409
Keratin-associated protein 10-8 (KRTAP10-8) KRTAP type 10 family P60410
Keratin-associated protein 10-9 (KRTAP10-9) KRTAP type 10 family P60411
Keratin-associated protein 5-9 (KRTAP5-9) KRTAP type 5 family P26371
Protein LDOC1 (LDOC1) LDOC1 family O95751
Leucine zipper putative tumor suppressor 2 (LZTS2) LZTS2 family Q9BRK4
Harmonin-binding protein USHBP1 (USHBP1) MCC family Q8N6Y0
NGFI-A-binding protein 2 (NAB2) NAB family Q15742
Notch homolog 2 N-terminal-like protein A (NOTCH2NLA) NOTCH family Q7Z3S9
Notch homolog 2 N-terminal-like protein C (NOTCH2NLC) NOTCH family P0DPK4
Nucleosome assembly protein 1-like 2 (NAP1L2) Nucleosome assembly protein (NAP) family Q9ULW6
PIH1 domain-containing protein 1 (PIH1D1) PIH1 family Q9NWS0
Paraneoplastic antigen Ma1 (PNMA1) PNMA family Q8ND90
Paraneoplastic antigen Ma2 (PNMA2) PNMA family Q9UL42
Prefoldin subunit 5 (PFDN5) Prefoldin subunit alpha family Q99471
Proline-rich protein 5-like (PRR5L) PROTOR family Q6MZQ0
RNA-binding protein 48 (RBM48) RBM48 family Q5RL73
RAD50-interacting protein 1 (RINT1) RINT1 family Q6NUQ1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGRIP1) RPGRIP1 family Q96KN7
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (SMARCD1) SMARCD family Q96GM5
Synaptonemal complex central element protein 1 (SYCE1) SYCE family Q8N0S2
Syntaxin-11 (STX11) Syntaxin family O75558
Tuftelin-interacting protein 11 (TFIP11) TFP11/STIP family Q9UBB9
Troponin I, slow skeletal muscle (TNNI1) Troponin I family P19237
Vacuolar protein sorting-associated protein 52 homolog (VPS52) VPS52 family Q8N1B4
TLE family member 5 (TLE5) WD repeat Groucho/TLE family Q08117
Arginine vasopressin-induced protein 1 (AVPI1) . Q5T686
Axin-2 (AXIN2) . Q9Y2T1
Brorin (VWC2) . Q2TAL6
Calcium and integrin-binding family member 3 (CIB3) . Q96Q77
Caspase recruitment domain-containing protein 10 (CARD10) . Q9BWT7
Centrosomal protein of 44 kDa (CEP44) . Q9C0F1
Centrosomal protein of 70 kDa (CEP70) . Q8NHQ1
Cytohesin-interacting protein (CYTIP) . O60759
EZH inhibitory protein (EZHIP) . Q86X51
Fibroblast growth factor receptor substrate 3 (FRS3) . O43559
Fibronectin type III domain-containing protein 11 (FNDC11) . Q9BVV2
Four and a half LIM domains protein 2 (FHL2) . Q14192
Four and a half LIM domains protein 5 (FHL5) . Q5TD97
Heat shock factor 2-binding protein (HSF2BP) . O75031
Huntingtin-associated protein 1 (HAP1) . P54257
KATNB1-like protein 1 (KATNBL1) . Q9H079
KN motif and ankyrin repeat domain-containing protein 2 (KANK2) . Q63ZY3
LRP2-binding protein (LRP2BP) . Q9P2M1
Mirror-image polydactyly gene 1 protein (MIPOL1) . Q8TD10
MORN repeat-containing protein 3 (MORN3) . Q6PF18
Myomegalin (PDE4DIP) . Q5VU43
PDZ and LIM domain protein 7 (PDLIM7) . Q9NR12
PRKCA-binding protein (PICK1) . Q9NRD5
Proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1) . O43586
Protein phosphatase 1 regulatory inhibitor subunit 16B (PPP1R16B) . Q96T49
Protein phosphatase 1 regulatory subunit 16A (PPP1R16A) . Q96I34
Putative protein MSS51 homolog, mitochondrial (MSS51) . Q4VC12
Rab effector Noc2 (RPH3AL) . Q9UNE2
RAD52 motif-containing protein 1 (RDM1) . Q8NG50
Splicing regulator RBM11 (RBM11) . P57052
Sprouty-related, EVH1 domain-containing protein 1 (SPRED1) . Q7Z699
Tax1-binding protein 1 (TAX1BP1) . Q86VP1
Tetratricopeptide repeat protein 23-like (TTC23L) . Q6PF05
TNF receptor-associated factor 1 (TRAF1) . Q13077
UBX domain-containing protein 11 (UBXN11) . Q5T124
Vimentin-type intermediate filament-associated coiled-coil protein (VMAC) . Q2NL98
Vinexin (SORBS3) . O60504
Zinc finger MYND domain-containing protein 12 (ZMYND12) . Q9H0C1

References

1 A Chemical Proteomic Map of Heme-Protein Interactions. J Am Chem Soc. 2022 Aug 24;144(33):15013-15019. doi: 10.1021/jacs.2c06104. Epub 2022 Aug 12.
Mass spectrometry data entry: PXD034651
2 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
5 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
6 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
7 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578