Details of the Target

General Information of Target

Target ID LDTP10174
Target Name ELL-associated factor 2 (EAF2)
Gene Name EAF2
Gene ID 55840
Synonyms
TRAITS; ELL-associated factor 2; Testosterone-regulated apoptosis inducer and tumor suppressor protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MRPQGPAASPQRLRGLLLLLLLQLPAPSSASEIPKGKQKAQLRQREVVDLYNGMCLQGPA
GVPGRDGSPGANGIPGTPGIPGRDGFKGEKGECLRESFEESWTPNYKQCSWSSLNYGIDL
GKIAECTFTKMRSNSALRVLFSGSLRLKCRNACCQRWYFTFNGAECSGPLPIEAIIYLDQ
GSPEMNSTINIHRTSSVEGLCEGIGAGLVDVAIWVGTCSDYPKGDASTGWNSVSRIIIEE
LPK
Target Bioclass
Other
Family
EAF family
Subcellular location
Nucleus speckle
Function
Acts as a transcriptional transactivator of TCEA1 elongation activity. Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo.
Uniprot ID
Q96CJ1
Ensemble ID
ENST00000273668.7
HGNC ID
HGNC:23115

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
MOLM13 SNV: p.T137A .
SNU1079 SNV: p.R13S .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C29(0.92)  LDD0532  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C87(0.90); C98(0.98)  LDD0812  [1]
 LDCM0215  AC10 HCT 116 C29(0.92)  LDD0532  [1]
 LDCM0216  AC100 HEK-293T C29(0.79); C87(0.94); C98(1.09)  LDD0814  [1]
 LDCM0217  AC101 HEK-293T C29(0.90); C87(0.91); C98(0.92)  LDD0815  [1]
 LDCM0218  AC102 HEK-293T C29(1.04); C87(0.95); C98(0.92)  LDD0816  [1]
 LDCM0219  AC103 HEK-293T C29(0.98); C87(0.92); C98(0.99)  LDD0817  [1]
 LDCM0220  AC104 HEK-293T C29(1.07); C87(1.02); C98(1.02)  LDD0818  [1]
 LDCM0221  AC105 HEK-293T C29(1.11); C87(1.14); C98(1.10)  LDD0819  [1]
 LDCM0222  AC106 HEK-293T C29(1.00); C87(1.04); C98(1.12)  LDD0820  [1]
 LDCM0223  AC107 HEK-293T C29(1.05); C87(1.03); C98(1.08)  LDD0821  [1]
 LDCM0224  AC108 HEK-293T C29(0.76); C87(0.88); C98(1.00)  LDD0822  [1]
 LDCM0225  AC109 HEK-293T C29(0.93); C87(0.94); C98(0.98)  LDD0823  [1]
 LDCM0226  AC11 HCT 116 C29(0.96)  LDD0543  [1]
 LDCM0227  AC110 HEK-293T C29(1.09); C87(1.02); C98(1.14)  LDD0825  [1]
 LDCM0228  AC111 HEK-293T C29(1.11); C87(1.06); C98(1.27)  LDD0826  [1]
 LDCM0229  AC112 HEK-293T C29(1.11); C87(1.09); C98(1.21)  LDD0827  [1]
 LDCM0230  AC113 HEK-293T C29(0.91); C87(0.91); C98(0.89)  LDD0828  [1]
 LDCM0231  AC114 HEK-293T C29(1.25); C87(1.25); C98(0.86)  LDD0829  [1]
 LDCM0232  AC115 HEK-293T C29(0.79); C87(0.79); C98(0.88)  LDD0830  [1]
 LDCM0233  AC116 HEK-293T C29(0.96); C87(0.96); C98(0.80)  LDD0831  [1]
 LDCM0234  AC117 HEK-293T C29(0.99); C87(0.99); C98(0.89)  LDD0832  [1]
 LDCM0235  AC118 HEK-293T C29(1.06); C87(1.06); C98(0.82)  LDD0833  [1]
 LDCM0236  AC119 HEK-293T C29(0.93); C87(0.93); C98(0.88)  LDD0834  [1]
 LDCM0237  AC12 HCT 116 C29(0.94)  LDD0554  [1]
 LDCM0238  AC120 HEK-293T C29(1.03); C87(1.03); C98(0.89)  LDD0836  [1]
 LDCM0239  AC121 HEK-293T C29(1.02); C87(1.02); C98(0.96)  LDD0837  [1]
 LDCM0240  AC122 HEK-293T C29(0.90); C87(0.90); C98(1.03)  LDD0838  [1]
 LDCM0241  AC123 HEK-293T C29(0.89); C87(0.89); C98(1.02)  LDD0839  [1]
 LDCM0242  AC124 HEK-293T C29(1.03); C87(1.03); C98(0.89)  LDD0840  [1]
 LDCM0243  AC125 HEK-293T C29(0.95); C87(0.95); C98(0.98)  LDD0841  [1]
 LDCM0244  AC126 HEK-293T C29(1.23); C87(1.23); C98(1.15)  LDD0842  [1]
 LDCM0245  AC127 HEK-293T C29(1.04); C87(1.04); C98(1.30)  LDD0843  [1]
 LDCM0246  AC128 HEK-293T C29(0.92); C87(1.18); C98(1.05)  LDD0844  [1]
 LDCM0247  AC129 HEK-293T C29(1.01); C87(1.22); C98(1.04)  LDD0845  [1]
 LDCM0249  AC130 HEK-293T C29(0.79); C87(1.13); C98(0.97)  LDD0847  [1]
 LDCM0250  AC131 HEK-293T C29(0.85); C87(1.18); C98(1.03)  LDD0848  [1]
 LDCM0251  AC132 HEK-293T C29(1.17); C87(1.13); C98(0.97)  LDD0849  [1]
 LDCM0252  AC133 HEK-293T C29(0.92); C87(1.32); C98(1.10)  LDD0850  [1]
 LDCM0253  AC134 HEK-293T C29(0.85); C87(1.18); C98(1.02)  LDD0851  [1]
 LDCM0254  AC135 HEK-293T C29(0.98); C87(1.01); C98(1.00)  LDD0852  [1]
 LDCM0255  AC136 HEK-293T C29(1.08); C87(1.41); C98(1.16)  LDD0853  [1]
 LDCM0256  AC137 HEK-293T C29(1.29); C87(1.23); C98(1.15)  LDD0854  [1]
 LDCM0257  AC138 HEK-293T C29(0.91); C87(1.12); C98(1.16)  LDD0855  [1]
 LDCM0258  AC139 HEK-293T C29(1.02); C87(1.18); C98(1.15)  LDD0856  [1]
 LDCM0259  AC14 HCT 116 C29(0.64)  LDD0576  [1]
 LDCM0260  AC140 HEK-293T C29(0.98); C87(1.50); C98(1.21)  LDD0858  [1]
 LDCM0261  AC141 HEK-293T C29(1.10); C87(1.08); C98(1.06)  LDD0859  [1]
 LDCM0262  AC142 HEK-293T C29(1.06); C87(1.26); C98(1.10)  LDD0860  [1]
 LDCM0263  AC143 HCT 116 C29(1.23)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C29(1.08)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C29(1.02)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C29(1.35)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C29(1.12)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C29(1.43)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C29(1.13)  LDD0586  [1]
 LDCM0270  AC15 HCT 116 C29(1.18)  LDD0587  [1]
 LDCM0271  AC150 HCT 116 C29(1.26)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C29(1.10)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C29(1.01)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C29(1.30)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C29(1.23)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C29(1.04)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C29(1.00)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C29(0.99)  LDD2161  [1]
 LDCM0279  AC2 HEK-293T C87(1.79); C98(1.33)  LDD0877  [1]
 LDCM0285  AC25 HEK-293T C87(1.03); C98(1.03)  LDD0883  [1]
 LDCM0286  AC26 HEK-293T C87(0.73); C98(0.73)  LDD0884  [1]
 LDCM0287  AC27 HEK-293T C87(0.81); C98(0.81)  LDD0885  [1]
 LDCM0288  AC28 HEK-293T C87(1.12); C98(1.12)  LDD0886  [1]
 LDCM0289  AC29 HEK-293T C87(0.72); C98(0.72)  LDD0887  [1]
 LDCM0290  AC3 HEK-293T C87(1.08); C98(1.08)  LDD0888  [1]
 LDCM0291  AC30 HEK-293T C87(0.77); C98(0.77)  LDD0889  [1]
 LDCM0292  AC31 HEK-293T C87(0.80); C98(0.80)  LDD0890  [1]
 LDCM0293  AC32 HEK-293T C87(0.83); C98(0.83)  LDD0891  [1]
 LDCM0294  AC33 HEK-293T C87(0.96); C98(0.96)  LDD0892  [1]
 LDCM0295  AC34 HEK-293T C87(1.01); C98(1.01)  LDD0893  [1]
 LDCM0296  AC35 HCT 116 C29(0.47)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C29(0.88)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C29(0.99)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C29(0.77)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C29(0.90)  LDD0617  [1]
 LDCM0301  AC4 HEK-293T C87(0.86); C98(0.93)  LDD0899  [1]
 LDCM0302  AC40 HCT 116 C29(0.62)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C29(1.00)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C29(0.88)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C29(0.92)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C29(1.14)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C29(1.22)  LDD0624  [1]
 LDCM0308  AC46 HCT 116 C29(0.98)  LDD0625  [1]
 LDCM0309  AC47 HCT 116 C29(0.93)  LDD0626  [1]
 LDCM0310  AC48 HCT 116 C29(0.99)  LDD0627  [1]
 LDCM0311  AC49 HCT 116 C29(0.93)  LDD0628  [1]
 LDCM0312  AC5 HEK-293T C87(1.16); C98(1.02)  LDD0910  [1]
 LDCM0313  AC50 HCT 116 C29(0.92)  LDD0630  [1]
 LDCM0314  AC51 HCT 116 C29(0.84)  LDD0631  [1]
 LDCM0315  AC52 HCT 116 C29(0.81)  LDD0632  [1]
 LDCM0316  AC53 HCT 116 C29(0.92)  LDD0633  [1]
 LDCM0317  AC54 HCT 116 C29(1.07)  LDD0634  [1]
 LDCM0318  AC55 HCT 116 C29(1.06)  LDD0635  [1]
 LDCM0319  AC56 HCT 116 C29(0.89)  LDD0636  [1]
 LDCM0320  AC57 HCT 116 C29(1.73)  LDD0637  [1]
 LDCM0321  AC58 HCT 116 C29(1.79)  LDD0638  [1]
 LDCM0322  AC59 HCT 116 C29(1.55)  LDD0639  [1]
 LDCM0323  AC6 HCT 116 C29(0.87)  LDD0640  [1]
 LDCM0324  AC60 HCT 116 C29(1.58)  LDD0641  [1]
 LDCM0325  AC61 HCT 116 C29(1.44)  LDD0642  [1]
 LDCM0326  AC62 HCT 116 C29(1.59)  LDD0643  [1]
 LDCM0327  AC63 HCT 116 C29(1.57)  LDD0644  [1]
 LDCM0328  AC64 HCT 116 C29(1.90)  LDD0645  [1]
 LDCM0329  AC65 HCT 116 C29(2.46)  LDD0646  [1]
 LDCM0330  AC66 HCT 116 C29(1.99)  LDD0647  [1]
 LDCM0331  AC67 HCT 116 C29(2.21)  LDD0648  [1]
 LDCM0332  AC68 HCT 116 C29(1.06)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C29(0.97)  LDD0650  [1]
 LDCM0334  AC7 HCT 116 C29(0.92)  LDD0651  [1]
 LDCM0335  AC70 HCT 116 C29(0.95)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C29(1.16)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C29(1.33)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C29(1.29)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C29(1.06)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C29(1.23)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C29(1.19)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C29(0.99)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C29(0.91)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C29(1.04)  LDD0661  [1]
 LDCM0345  AC8 HCT 116 C29(1.12)  LDD0662  [1]
 LDCM0346  AC80 HCT 116 C29(1.19)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C29(1.17)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C29(1.10)  LDD0665  [1]
 LDCM0349  AC83 HCT 116 C29(1.58)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C29(1.41)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C29(1.45)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C29(1.50)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C29(1.44)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C29(1.62)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C29(1.44)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C29(1.63)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C29(0.99)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C29(1.32)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C29(1.36)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C29(1.09)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C29(1.35)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C29(0.98)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C29(1.43)  LDD0681  [1]
 LDCM0365  AC98 HEK-293T C29(1.03); C87(0.97); C98(0.94)  LDD0963  [1]
 LDCM0366  AC99 HEK-293T C29(0.98); C87(1.07); C98(1.06)  LDD0964  [1]
 LDCM0248  AKOS034007472 HCT 116 C29(1.11)  LDD0565  [1]
 LDCM0356  AKOS034007680 HCT 116 C29(1.12)  LDD0673  [1]
 LDCM0275  AKOS034007705 HCT 116 C29(1.13)  LDD0592  [1]
 LDCM0369  CL100 HEK-293T C87(1.11); C98(0.97)  LDD0967  [1]
 LDCM0370  CL101 HCT 116 C29(0.50)  LDD0687  [1]
 LDCM0371  CL102 HCT 116 C29(0.52)  LDD0688  [1]
 LDCM0372  CL103 HCT 116 C29(0.85)  LDD0689  [1]
 LDCM0373  CL104 HCT 116 C29(0.75)  LDD0690  [1]
 LDCM0382  CL112 HEK-293T C87(0.60); C98(0.60)  LDD0980  [1]
 LDCM0383  CL113 HEK-293T C87(0.73); C98(0.73)  LDD0981  [1]
 LDCM0384  CL114 HEK-293T C87(0.78); C98(0.78)  LDD0982  [1]
 LDCM0385  CL115 HEK-293T C87(0.62); C98(0.62)  LDD0983  [1]
 LDCM0386  CL116 HEK-293T C87(0.69); C98(0.69)  LDD0984  [1]
 LDCM0387  CL117 HCT 116 C29(0.89)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C29(0.99)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C29(0.68)  LDD0706  [1]
 LDCM0391  CL120 HCT 116 C29(0.71)  LDD0708  [1]
 LDCM0392  CL121 HCT 116 C29(0.98)  LDD0709  [1]
 LDCM0393  CL122 HCT 116 C29(0.91)  LDD0710  [1]
 LDCM0394  CL123 HCT 116 C29(0.84)  LDD0711  [1]
 LDCM0395  CL124 HCT 116 C29(0.96)  LDD0712  [1]
 LDCM0396  CL125 HCT 116 C29(1.35)  LDD0713  [1]
 LDCM0397  CL126 HCT 116 C29(1.40)  LDD0714  [1]
 LDCM0398  CL127 HCT 116 C29(1.51)  LDD0715  [1]
 LDCM0399  CL128 HCT 116 C29(1.69)  LDD0716  [1]
 LDCM0403  CL16 HEK-293T C29(1.52); C87(1.24); C98(1.06)  LDD1001  [1]
 LDCM0404  CL17 HEK-293T C29(0.90); C87(0.76); C98(0.81)  LDD1002  [1]
 LDCM0405  CL18 HEK-293T C29(1.20); C87(1.10); C98(1.04)  LDD1003  [1]
 LDCM0406  CL19 HEK-293T C29(0.97); C87(1.03); C98(1.07)  LDD1004  [1]
 LDCM0408  CL20 HEK-293T C29(1.03); C87(1.02); C98(1.06)  LDD1006  [1]
 LDCM0409  CL21 HEK-293T C29(0.76); C87(0.76); C98(0.96)  LDD1007  [1]
 LDCM0410  CL22 HEK-293T C29(1.12); C87(1.23); C98(1.21)  LDD1008  [1]
 LDCM0411  CL23 HEK-293T C29(0.90); C87(0.89); C98(1.01)  LDD1009  [1]
 LDCM0412  CL24 HEK-293T C29(1.01); C87(0.96); C98(0.96)  LDD1010  [1]
 LDCM0413  CL25 HEK-293T C29(0.78); C87(0.74); C98(0.91)  LDD1011  [1]
 LDCM0414  CL26 HEK-293T C29(1.19); C87(1.01); C98(0.93)  LDD1012  [1]
 LDCM0415  CL27 HEK-293T C29(1.03); C87(1.20); C98(1.19)  LDD1013  [1]
 LDCM0416  CL28 HEK-293T C29(0.85); C87(0.80); C98(0.87)  LDD1014  [1]
 LDCM0417  CL29 HEK-293T C29(0.94); C87(0.98); C98(1.03)  LDD1015  [1]
 LDCM0419  CL30 HEK-293T C29(0.87); C87(0.93); C98(1.18)  LDD1017  [1]
 LDCM0420  CL31 HEK-293T C29(1.07); C87(1.07); C98(0.97)  LDD1018  [1]
 LDCM0421  CL32 HEK-293T C29(1.31); C87(1.31); C98(0.83)  LDD1019  [1]
 LDCM0422  CL33 HEK-293T C29(1.08); C87(1.08); C98(0.74)  LDD1020  [1]
 LDCM0423  CL34 HEK-293T C29(1.11); C87(1.11); C98(1.01)  LDD1021  [1]
 LDCM0424  CL35 HEK-293T C29(1.10); C87(1.10); C98(0.75)  LDD1022  [1]
 LDCM0425  CL36 HEK-293T C29(0.98); C87(0.98); C98(0.83)  LDD1023  [1]
 LDCM0426  CL37 HEK-293T C29(1.19); C87(1.19); C98(0.76)  LDD1024  [1]
 LDCM0428  CL39 HEK-293T C29(1.43); C87(1.43); C98(1.02)  LDD1026  [1]
 LDCM0430  CL40 HEK-293T C29(1.62); C87(1.62); C98(0.85)  LDD1028  [1]
 LDCM0431  CL41 HEK-293T C29(1.14); C87(1.14); C98(0.84)  LDD1029  [1]
 LDCM0432  CL42 HEK-293T C29(0.93); C87(0.93); C98(0.81)  LDD1030  [1]
 LDCM0433  CL43 HEK-293T C29(0.90); C87(0.90); C98(0.93)  LDD1031  [1]
 LDCM0434  CL44 HEK-293T C29(1.51); C87(1.51); C98(0.73)  LDD1032  [1]
 LDCM0435  CL45 HEK-293T C29(0.99); C87(0.99); C98(0.78)  LDD1033  [1]
 LDCM0436  CL46 HEK-293T C29(3.06); C87(3.06); C98(1.08)  LDD1034  [1]
 LDCM0437  CL47 HEK-293T C29(1.19); C87(1.19); C98(0.97)  LDD1035  [1]
 LDCM0438  CL48 HEK-293T C29(1.36); C87(1.36); C98(1.07)  LDD1036  [1]
 LDCM0439  CL49 HEK-293T C29(1.04); C87(1.04); C98(1.01)  LDD1037  [1]
 LDCM0441  CL50 HEK-293T C29(1.50); C87(1.50); C98(1.30)  LDD1039  [1]
 LDCM0442  CL51 HEK-293T C29(1.19); C87(1.19); C98(1.01)  LDD1040  [1]
 LDCM0443  CL52 HEK-293T C29(2.17); C87(2.17); C98(1.23)  LDD1041  [1]
 LDCM0444  CL53 HEK-293T C29(0.80); C87(0.80); C98(1.15)  LDD1042  [1]
 LDCM0445  CL54 HEK-293T C29(1.03); C87(1.03); C98(1.11)  LDD1043  [1]
 LDCM0446  CL55 HEK-293T C29(1.61); C87(1.61); C98(0.98)  LDD1044  [1]
 LDCM0447  CL56 HEK-293T C29(1.56); C87(1.56); C98(1.08)  LDD1045  [1]
 LDCM0448  CL57 HEK-293T C29(1.15); C87(1.15); C98(0.94)  LDD1046  [1]
 LDCM0449  CL58 HEK-293T C29(1.46); C87(1.46); C98(1.10)  LDD1047  [1]
 LDCM0450  CL59 HEK-293T C29(1.47); C87(1.47); C98(1.13)  LDD1048  [1]
 LDCM0452  CL60 HEK-293T C29(1.48); C87(1.48); C98(1.21)  LDD1050  [1]
 LDCM0453  CL61 HCT 116 C29(1.08)  LDD0770  [1]
 LDCM0454  CL62 HCT 116 C29(1.01)  LDD0771  [1]
 LDCM0455  CL63 HCT 116 C29(1.22)  LDD0772  [1]
 LDCM0456  CL64 HCT 116 C29(1.38)  LDD0773  [1]
 LDCM0457  CL65 HCT 116 C29(1.16)  LDD0774  [1]
 LDCM0458  CL66 HCT 116 C29(1.50)  LDD0775  [1]
 LDCM0459  CL67 HCT 116 C29(1.19)  LDD0776  [1]
 LDCM0460  CL68 HCT 116 C29(1.46)  LDD0777  [1]
 LDCM0461  CL69 HCT 116 C29(1.11)  LDD0778  [1]
 LDCM0463  CL70 HCT 116 C29(1.20)  LDD0780  [1]
 LDCM0464  CL71 HCT 116 C29(1.18)  LDD0781  [1]
 LDCM0465  CL72 HCT 116 C29(1.29)  LDD0782  [1]
 LDCM0466  CL73 HCT 116 C29(1.18)  LDD0783  [1]
 LDCM0467  CL74 HCT 116 C29(1.22)  LDD0784  [1]
 LDCM0486  CL91 HEK-293T C87(1.29); C98(1.13)  LDD1084  [1]
 LDCM0487  CL92 HEK-293T C87(1.27); C98(1.16)  LDD1085  [1]
 LDCM0488  CL93 HEK-293T C87(0.79); C98(0.90)  LDD1086  [1]
 LDCM0489  CL94 HEK-293T C87(0.95); C98(0.89)  LDD1087  [1]
 LDCM0490  CL95 HEK-293T C87(2.05); C98(1.41)  LDD1088  [1]
 LDCM0491  CL96 HEK-293T C87(1.19); C98(0.98)  LDD1089  [1]
 LDCM0492  CL97 HEK-293T C87(1.36); C98(1.08)  LDD1090  [1]
 LDCM0493  CL98 HEK-293T C87(1.13); C98(1.03)  LDD1091  [1]
 LDCM0494  CL99 HEK-293T C87(1.34); C98(1.15)  LDD1092  [1]
 LDCM0468  Fragment33 HCT 116 C29(1.20)  LDD0785  [1]
 LDCM0427  Fragment51 HEK-293T C29(1.13); C87(1.13); C98(0.85)  LDD1025  [1]
 LDCM0022  KB02 Karpas-422 C29(2.22)  LDD2413  [2]
 LDCM0023  KB03 Karpas-422 C29(2.98)  LDD2830  [2]
 LDCM0024  KB05 OPM-2 C29(2.12)  LDD3377  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Baculoviral IAP repeat-containing protein 2 (BIRC2) IAP family Q13490
E3 ubiquitin-protein ligase TRIM23 (TRIM23) Arf family P36406
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Hypoxia-inducible factor 1-alpha (HIF1A) . Q16665
Other
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Proteasome activator complex subunit 3 (PSME3) PA28 family P61289
Transcription elongation factor A protein 2 (TCEA2) TFS-II family Q15560
TCF3 fusion partner (TFPT) . P0C1Z6

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840