Details of the Target

General Information of Target

Target ID LDTP08174
Target Name Adhesion G-protein coupled receptor G6 (ADGRG6)
Gene Name ADGRG6
Gene ID 57211
Synonyms
DREG; GPR126; VIGR; Adhesion G-protein coupled receptor G6; Developmentally regulated G-protein-coupled receptor; G-protein coupled receptor 126; Vascular inducible G protein-coupled receptor) [Cleaved into: ADGRG6 N-terminal fragment; ADGRG6-NTF; ADGRG6 C-terminal fragment; ADGRG6-CTF)]
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MMFRSDRMWSCHWKWKPSPLLFLFALYIMCVPHSVWGCANCRVVLSNPSGTFTSPCYPND
YPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGLSF
NSSANEMHVSFSSDFSIQKKGFNASYIRVAVSLRNQKVILPQTSDAYQVSVAKSISIPEL
SAFTLCFEATKVGHEDSDWTAFSYSNASFTQLLSFGKAKSGYFLSISDSKCLLNNALPVK
EKEDIFAESFEQLCLVWNNSLGSIGVNFKRNYETVPCDSTISKVIPGNGKLLLGSNQNEI
VSLKGDIYNFRLWNFTMNAKILSNLSCNVKGNVVDWQNDFWNIPNLALKAESNLSCGSYL
IPLPAAELASCADLGTLCQATVNSPSTTPPTVTTNMPVTNRIDKQRNDGIIYRISVVIQN
ILRHPEVKVQSKVAEWLNSTFQNWNYTVYVVNISFHLSAGEDKIKVKRSLEDEPRLVLWA
LLVYNATNNTNLEGKIIQQKLLKNNESLDEGLRLHTVNVRQLGHCLAMEEPKGYYWPSIQ
PSEYVLPCPDKPGFSASRICFYNATNPLVTYWGPVDISNCLKEANEVANQILNLTADGQN
LTSANITNIVEQVKRIVNKEENIDITLGSTLMNIFSNILSSSDSDLLESSSEALKTIDEL
AFKIDLNSTSHVNITTRNLALSVSSLLPGTNAISNFSIGLPSNNESYFQMDFESGQVDPL
ASVILPPNLLENLSPEDSVLVRRAQFTFFNKTGLFQDVGPQRKTLVSYVMACSIGNITIQ
NLKDPVQIKIKHTRTQEVHHPICAFWDLNKNKSFGGWNTSGCVAHRDSDASETVCLCNHF
THFGVLMDLPRSASQLDARNTKVLTFISYIGCGISAIFSAATLLTYVAFEKLRRDYPSKI
LMNLSTALLFLNLLFLLDGWITSFNVDGLCIAVAVLLHFFLLATFTWMGLEAIHMYIALV
KVFNTYIRRYILKFCIIGWGLPALVVSVVLASRNNNEVYGKESYGKEKGDEFCWIQDPVI
FYVTCAGYFGVMFFLNIAMFIVVMVQICGRNGKRSNRTLREEVLRNLRSVVSLTFLLGMT
WGFAFFAWGPLNIPFMYLFSIFNSLQGLFIFIFHCAMKENVQKQWRQHLCCGRFRLADNS
DWSKTATNIIKKSSDNLGKSLSSSSIGSNSTYLTSKSKSSSTTYFKRNSHTDNVSYEHSF
NKSGSLRQCFHGQVLVKTGPC
Target Bioclass
GPCR
Family
G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Subcellular location
Cell membrane
Function
G-protein coupled receptor which is activated by type IV collagen, a major constituent of the basement membrane. Couples to G(i)-proteins as well as G(s)-proteins. Essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons. Regulates neural, cardiac and ear development via G-protein- and/or N-terminus-dependent signaling. May act as a receptor for PRNP which may promote myelin homeostasis.
Uniprot ID
Q86SQ4
Ensemble ID
ENST00000230173.10
HGNC ID
HGNC:13841
ChEMBL ID
CHEMBL4523884

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C1209(0.83)  LDD0531  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C1209(0.83)  LDD0531  [1]
 LDCM0215  AC10 HCT 116 C1209(1.11)  LDD0532  [1]
 LDCM0216  AC100 HCT 116 C1209(0.86)  LDD0533  [1]
 LDCM0217  AC101 HCT 116 C1209(0.78)  LDD0534  [1]
 LDCM0218  AC102 HCT 116 C1209(0.76)  LDD0535  [1]
 LDCM0219  AC103 HCT 116 C1209(1.06)  LDD0536  [1]
 LDCM0220  AC104 HCT 116 C1209(0.87)  LDD0537  [1]
 LDCM0221  AC105 HCT 116 C1209(0.92)  LDD0538  [1]
 LDCM0222  AC106 HCT 116 C1209(0.99)  LDD0539  [1]
 LDCM0223  AC107 HCT 116 C1209(0.93)  LDD0540  [1]
 LDCM0224  AC108 HCT 116 C1209(0.91)  LDD0541  [1]
 LDCM0225  AC109 HCT 116 C1209(0.83)  LDD0542  [1]
 LDCM0226  AC11 HCT 116 C1209(1.21)  LDD0543  [1]
 LDCM0227  AC110 HCT 116 C1209(0.76)  LDD0544  [1]
 LDCM0228  AC111 HCT 116 C1209(0.72)  LDD0545  [1]
 LDCM0229  AC112 HCT 116 C1209(0.83)  LDD0546  [1]
 LDCM0230  AC113 HCT 116 C1209(0.95)  LDD0547  [1]
 LDCM0231  AC114 HCT 116 C1209(0.91)  LDD0548  [1]
 LDCM0232  AC115 HCT 116 C1209(0.93)  LDD0549  [1]
 LDCM0233  AC116 HCT 116 C1209(1.12)  LDD0550  [1]
 LDCM0234  AC117 HCT 116 C1209(0.91)  LDD0551  [1]
 LDCM0235  AC118 HCT 116 C1209(0.80)  LDD0552  [1]
 LDCM0236  AC119 HCT 116 C1209(1.04)  LDD0553  [1]
 LDCM0237  AC12 HCT 116 C1209(1.04)  LDD0554  [1]
 LDCM0238  AC120 HCT 116 C1209(0.92)  LDD0555  [1]
 LDCM0239  AC121 HCT 116 C1209(0.83)  LDD0556  [1]
 LDCM0240  AC122 HCT 116 C1209(1.08)  LDD0557  [1]
 LDCM0241  AC123 HCT 116 C1209(0.87)  LDD0558  [1]
 LDCM0242  AC124 HCT 116 C1209(0.87)  LDD0559  [1]
 LDCM0243  AC125 HCT 116 C1209(0.85)  LDD0560  [1]
 LDCM0244  AC126 HCT 116 C1209(0.93)  LDD0561  [1]
 LDCM0245  AC127 HCT 116 C1209(0.85)  LDD0562  [1]
 LDCM0246  AC128 PaTu 8988t C1209(1.23)  LDD1125  [1]
 LDCM0247  AC129 PaTu 8988t C1209(1.15)  LDD1126  [1]
 LDCM0249  AC130 PaTu 8988t C1209(1.13)  LDD1128  [1]
 LDCM0250  AC131 PaTu 8988t C1209(1.11)  LDD1129  [1]
 LDCM0251  AC132 PaTu 8988t C1209(1.11)  LDD1130  [1]
 LDCM0252  AC133 PaTu 8988t C1209(1.45)  LDD1131  [1]
 LDCM0253  AC134 PaTu 8988t C1209(1.33)  LDD1132  [1]
 LDCM0254  AC135 PaTu 8988t C1209(1.39)  LDD1133  [1]
 LDCM0255  AC136 PaTu 8988t C1209(1.40)  LDD1134  [1]
 LDCM0256  AC137 PaTu 8988t C1209(1.40)  LDD1135  [1]
 LDCM0257  AC138 PaTu 8988t C1209(1.40)  LDD1136  [1]
 LDCM0258  AC139 PaTu 8988t C1209(1.30)  LDD1137  [1]
 LDCM0259  AC14 HCT 116 C1209(1.11)  LDD0576  [1]
 LDCM0260  AC140 PaTu 8988t C1209(1.28)  LDD1139  [1]
 LDCM0261  AC141 PaTu 8988t C1209(1.18)  LDD1140  [1]
 LDCM0262  AC142 PaTu 8988t C1209(1.32)  LDD1141  [1]
 LDCM0263  AC143 HCT 116 C1209(1.22)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C1209(1.23)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C1209(1.27)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C1209(1.43)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C1209(1.32)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C1209(1.63)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C1209(1.50)  LDD0586  [1]
 LDCM0270  AC15 HCT 116 C1209(1.19)  LDD0587  [1]
 LDCM0271  AC150 HCT 116 C1209(1.18)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C1209(1.08)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C1209(1.38)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C1209(1.83)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C1209(1.13)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C1209(1.26)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C1209(1.12)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C1209(1.04)  LDD2161  [1]
 LDCM0276  AC17 HCT 116 C1209(0.90)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C1209(1.16)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C1209(1.01)  LDD0595  [1]
 LDCM0279  AC2 HCT 116 C1209(0.95)  LDD0596  [1]
 LDCM0280  AC20 HCT 116 C1209(0.88)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C1209(0.95)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C1209(0.83)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C1209(0.99)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C1209(0.85)  LDD0601  [1]
 LDCM0290  AC3 HCT 116 C1209(0.88)  LDD0607  [1]
 LDCM0296  AC35 HCT 116 C1209(0.75)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C1209(0.84)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C1209(0.89)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C1209(0.83)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C1209(0.91)  LDD0617  [1]
 LDCM0301  AC4 HCT 116 C1209(0.80)  LDD0618  [1]
 LDCM0302  AC40 HCT 116 C1209(1.01)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C1209(0.81)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C1209(0.91)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C1209(0.85)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C1209(0.94)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C1209(1.08)  LDD0624  [1]
 LDCM0308  AC46 HCT 116 C1209(0.97)  LDD0625  [1]
 LDCM0309  AC47 HCT 116 C1209(1.02)  LDD0626  [1]
 LDCM0310  AC48 HCT 116 C1209(1.12)  LDD0627  [1]
 LDCM0311  AC49 HCT 116 C1209(1.32)  LDD0628  [1]
 LDCM0312  AC5 HCT 116 C1209(0.84)  LDD0629  [1]
 LDCM0313  AC50 HCT 116 C1209(1.26)  LDD0630  [1]
 LDCM0314  AC51 HCT 116 C1209(0.87)  LDD0631  [1]
 LDCM0315  AC52 HCT 116 C1209(0.98)  LDD0632  [1]
 LDCM0316  AC53 HCT 116 C1209(1.29)  LDD0633  [1]
 LDCM0317  AC54 HCT 116 C1209(1.20)  LDD0634  [1]
 LDCM0318  AC55 HCT 116 C1209(1.36)  LDD0635  [1]
 LDCM0319  AC56 HCT 116 C1209(1.76)  LDD0636  [1]
 LDCM0320  AC57 HCT 116 C1209(1.21)  LDD0637  [1]
 LDCM0321  AC58 HCT 116 C1209(1.04)  LDD0638  [1]
 LDCM0322  AC59 HCT 116 C1209(1.27)  LDD0639  [1]
 LDCM0323  AC6 HCT 116 C1209(1.17)  LDD0640  [1]
 LDCM0324  AC60 HCT 116 C1209(1.26)  LDD0641  [1]
 LDCM0325  AC61 HCT 116 C1209(1.15)  LDD0642  [1]
 LDCM0326  AC62 HCT 116 C1209(1.29)  LDD0643  [1]
 LDCM0327  AC63 HCT 116 C1209(1.20)  LDD0644  [1]
 LDCM0328  AC64 HCT 116 C1209(1.28)  LDD0645  [1]
 LDCM0329  AC65 HCT 116 C1209(1.40)  LDD0646  [1]
 LDCM0330  AC66 HCT 116 C1209(1.29)  LDD0647  [1]
 LDCM0331  AC67 HCT 116 C1209(1.37)  LDD0648  [1]
 LDCM0332  AC68 HCT 116 C1209(0.99)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C1209(0.97)  LDD0650  [1]
 LDCM0334  AC7 HCT 116 C1209(1.06)  LDD0651  [1]
 LDCM0335  AC70 HCT 116 C1209(1.04)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C1209(0.93)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C1209(1.22)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C1209(1.56)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C1209(1.64)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C1209(1.40)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C1209(1.07)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C1209(1.11)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C1209(1.02)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C1209(1.01)  LDD0661  [1]
 LDCM0345  AC8 HCT 116 C1209(1.17)  LDD0662  [1]
 LDCM0346  AC80 HCT 116 C1209(1.22)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C1209(0.94)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C1209(1.83)  LDD0665  [1]
 LDCM0349  AC83 HCT 116 C1209(1.53)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C1209(1.38)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C1209(1.60)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C1209(1.51)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C1209(1.33)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C1209(1.32)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C1209(1.54)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C1209(1.62)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C1209(1.33)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C1209(1.53)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C1209(1.34)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C1209(1.35)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C1209(1.50)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C1209(1.22)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C1209(1.85)  LDD0681  [1]
 LDCM0365  AC98 HCT 116 C1209(1.36)  LDD0682  [1]
 LDCM0366  AC99 HCT 116 C1209(0.82)  LDD0683  [1]
 LDCM0248  AKOS034007472 HCT 116 C1209(1.18)  LDD0565  [1]
 LDCM0356  AKOS034007680 HCT 116 C1209(1.21)  LDD0673  [1]
 LDCM0275  AKOS034007705 HCT 116 C1209(1.40)  LDD0592  [1]
 LDCM0367  CL1 HCT 116 C1209(1.28)  LDD0684  [1]
 LDCM0368  CL10 HCT 116 C1209(0.91)  LDD0685  [1]
 LDCM0369  CL100 HCT 116 C1209(0.96)  LDD0686  [1]
 LDCM0370  CL101 HCT 116 C1209(1.23)  LDD0687  [1]
 LDCM0371  CL102 HCT 116 C1209(1.13)  LDD0688  [1]
 LDCM0372  CL103 HCT 116 C1209(1.02)  LDD0689  [1]
 LDCM0373  CL104 HCT 116 C1209(1.04)  LDD0690  [1]
 LDCM0374  CL105 HCT 116 C1209(1.15)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C1209(1.26)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C1209(1.09)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C1209(1.31)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C1209(1.06)  LDD0695  [1]
 LDCM0379  CL11 HCT 116 C1209(1.53)  LDD0696  [1]
 LDCM0380  CL110 HCT 116 C1209(1.28)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C1209(1.13)  LDD0698  [1]
 LDCM0387  CL117 HCT 116 C1209(1.28)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C1209(0.94)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C1209(1.01)  LDD0706  [1]
 LDCM0390  CL12 HCT 116 C1209(0.93)  LDD0707  [1]
 LDCM0391  CL120 HCT 116 C1209(0.87)  LDD0708  [1]
 LDCM0392  CL121 HCT 116 C1209(0.92)  LDD0709  [1]
 LDCM0393  CL122 HCT 116 C1209(1.21)  LDD0710  [1]
 LDCM0394  CL123 HCT 116 C1209(1.40)  LDD0711  [1]
 LDCM0395  CL124 HCT 116 C1209(1.45)  LDD0712  [1]
 LDCM0396  CL125 HCT 116 C1209(1.01)  LDD0713  [1]
 LDCM0397  CL126 HCT 116 C1209(1.01)  LDD0714  [1]
 LDCM0398  CL127 HCT 116 C1209(1.03)  LDD0715  [1]
 LDCM0399  CL128 HCT 116 C1209(1.26)  LDD0716  [1]
 LDCM0400  CL13 HCT 116 C1209(0.79)  LDD0717  [1]
 LDCM0401  CL14 HCT 116 C1209(0.86)  LDD0718  [1]
 LDCM0402  CL15 HCT 116 C1209(0.97)  LDD0719  [1]
 LDCM0404  CL17 HCT 116 C1209(1.18)  LDD0721  [1]
 LDCM0405  CL18 HCT 116 C1209(0.94)  LDD0722  [1]
 LDCM0406  CL19 HCT 116 C1209(0.97)  LDD0723  [1]
 LDCM0407  CL2 HCT 116 C1209(1.13)  LDD0724  [1]
 LDCM0408  CL20 HCT 116 C1209(1.14)  LDD0725  [1]
 LDCM0409  CL21 HCT 116 C1209(1.91)  LDD0726  [1]
 LDCM0410  CL22 HCT 116 C1209(0.83)  LDD0727  [1]
 LDCM0411  CL23 HCT 116 C1209(1.03)  LDD0728  [1]
 LDCM0412  CL24 HCT 116 C1209(0.79)  LDD0729  [1]
 LDCM0413  CL25 HCT 116 C1209(1.05)  LDD0730  [1]
 LDCM0414  CL26 HCT 116 C1209(0.91)  LDD0731  [1]
 LDCM0415  CL27 HCT 116 C1209(0.80)  LDD0732  [1]
 LDCM0416  CL28 HCT 116 C1209(0.85)  LDD0733  [1]
 LDCM0417  CL29 HCT 116 C1209(0.97)  LDD0734  [1]
 LDCM0418  CL3 HCT 116 C1209(1.02)  LDD0735  [1]
 LDCM0419  CL30 HCT 116 C1209(1.02)  LDD0736  [1]
 LDCM0420  CL31 HCT 116 C1209(0.95)  LDD0737  [1]
 LDCM0429  CL4 HCT 116 C1209(1.10)  LDD0746  [1]
 LDCM0436  CL46 HCT 116 C1209(0.70)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C1209(0.78)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C1209(0.59)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C1209(0.84)  LDD0756  [1]
 LDCM0440  CL5 HCT 116 C1209(0.85)  LDD0757  [1]
 LDCM0441  CL50 HCT 116 C1209(0.84)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C1209(0.77)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C1209(0.78)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C1209(0.79)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C1209(0.65)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C1209(0.63)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C1209(0.81)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C1209(0.67)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C1209(0.65)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C1209(0.72)  LDD0767  [1]
 LDCM0451  CL6 HCT 116 C1209(1.18)  LDD0768  [1]
 LDCM0452  CL60 HCT 116 C1209(0.84)  LDD0769  [1]
 LDCM0462  CL7 HCT 116 C1209(0.79)  LDD0779  [1]
 LDCM0469  CL76 PaTu 8988t C1209(1.14)  LDD1348  [1]
 LDCM0470  CL77 PaTu 8988t C1209(1.19)  LDD1349  [1]
 LDCM0471  CL78 PaTu 8988t C1209(1.49)  LDD1350  [1]
 LDCM0472  CL79 PaTu 8988t C1209(1.23)  LDD1351  [1]
 LDCM0473  CL8 HCT 116 C1209(3.10)  LDD0790  [1]
 LDCM0474  CL80 PaTu 8988t C1209(1.39)  LDD1353  [1]
 LDCM0475  CL81 PaTu 8988t C1209(1.20)  LDD1354  [1]
 LDCM0476  CL82 PaTu 8988t C1209(1.55)  LDD1355  [1]
 LDCM0477  CL83 PaTu 8988t C1209(1.30)  LDD1356  [1]
 LDCM0478  CL84 PaTu 8988t C1209(0.99)  LDD1357  [1]
 LDCM0479  CL85 PaTu 8988t C1209(1.05)  LDD1358  [1]
 LDCM0480  CL86 PaTu 8988t C1209(1.38)  LDD1359  [1]
 LDCM0481  CL87 PaTu 8988t C1209(1.24)  LDD1360  [1]
 LDCM0482  CL88 PaTu 8988t C1209(1.51)  LDD1361  [1]
 LDCM0483  CL89 PaTu 8988t C1209(1.04)  LDD1362  [1]
 LDCM0484  CL9 HCT 116 C1209(0.80)  LDD0801  [1]
 LDCM0485  CL90 PaTu 8988t C1209(1.31)  LDD1364  [1]
 LDCM0486  CL91 HCT 116 C1209(0.89)  LDD0803  [1]
 LDCM0487  CL92 HCT 116 C1209(1.03)  LDD0804  [1]
 LDCM0488  CL93 HCT 116 C1209(0.91)  LDD0805  [1]
 LDCM0489  CL94 HCT 116 C1209(1.02)  LDD0806  [1]
 LDCM0490  CL95 HCT 116 C1209(1.16)  LDD0807  [1]
 LDCM0491  CL96 HCT 116 C1209(0.89)  LDD0808  [1]
 LDCM0492  CL97 HCT 116 C1209(0.93)  LDD0809  [1]
 LDCM0493  CL98 HCT 116 C1209(0.93)  LDD0810  [1]
 LDCM0494  CL99 HCT 116 C1209(0.84)  LDD0811  [1]
 LDCM0022  KB02 22RV1 C1209(2.40)  LDD2243  [2]
 LDCM0023  KB03 22RV1 C1209(3.42)  LDD2660  [2]
 LDCM0024  KB05 COLO792 C1209(1.72); C803(1.53)  LDD3310  [2]

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840