Details of the Target

General Information of Target

Target ID LDTP08065
Target Name Nephrocystin-3 (NPHP3)
Gene Name NPHP3
Gene ID 27031
Synonyms
KIAA2000; Nephrocystin-3
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MGTASSLVSPAGGEVIEDTYGAGGGEACEIPVEVKPKARLLRNSFRRGAGAAAGAGPGSL
PRGVGAGGLLGASFKSTGSSVPELEYAAAEYERLRKEYEIFRVSKNQELLSMGRREAKLD
TENKRLRAELQALQKTYQKILREKESALEAKYQAMERAATFEHDRDKVKRQFKIFRETKE
NEIQDLLRAKRELESKLQRLQAQGIQVFDPGESDSDDNCTDVTAAGTQCEYWTGGALGSE
PSIGSMIQLQQSFRGPEFAHSSIDVEGPFANVNRDDWDIAVASLLQVTPLFSHSLWSNTV
RCYLIYTDETQPEMDLFLKDYSPKLKRMCETMGYFFHAVYFPIDVENQYLTVRKWEIEKS
SLVILFIHLTLPSLLLEDCEEAFLKNPEGKPRLIFHRLEDGKVSSDSVQQLIDQVSNLNK
TSKAKIIDHSGDPAEGVYKTYICVEKIIKQDILGFENTDLETKDLGSEDSIPEEDDFGDV
LWDIHDEQEQMETFQQASNSAHELGFEKYYQRLNDLVAAPAPIPPLLVSGGPGSGKSLLL
SKWIQLQQKNSPNTLILSHFVGRPMSTSSESSLIIKRLTLKLMQHSWSVSALTLDPAKLL
EEFPRWLEKLSARHQGSIIIVIDSIDQVQQVEKHMKWLIDPLPVNVRVIVSVNVETCPPA
WRLWPTLHLDPLSPKDAKSIIIAECHSVDIKLSKEQEKKLERHCRSATTCNALYVTLFGK
MIARAGRAGNLDKILHQCFQCQDTLSLYRLVLHSIRESMANDVDKELMKQILCLVNVSHN
GVSESELMELYPEMSWTFLTSLIHSLYKMCLLTYGCGLLRFQHLQAWETVRLEYLEGPTV
TSSYRQKLINYFTLQLSQDRVTWRSADELPWLFQQQGSKQKLHDCLLNLFVSQNLYKRGH
FAELLSYWQFVGKDKSAMATEYFDSLKQYEKNCEGEDNMSCLADLYETLGRFLKDLGLLS
QAIVPLQRSLEIRETALDPDHPRVAQSLHQLASVYVQWKKFGNAEQLYKQALEISENAYG
ADHPYTARELEALATLYQKQNKYEQAEHFRKKSFKIHQKAIKKKGNLYGFALLRRRALQL
EELTLGKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLNN
LAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKMGKLDKAVPLY
ELAVEIRQKSFGPKHPSVATALVNLAVLYSQMKKHVEALPLYERALKIYEDSLGRMHPRV
GETLKNLAVLSYEGGDFEKAAELYKRAMEIKEAETSLLGGKAPSRHSSSGDTFSLKTAHS
PNVFLQQGQR
Target Bioclass
Other
Subcellular location
Cell projection, cilium
Function
Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.
Uniprot ID
Q7Z494
Ensemble ID
ENST00000337331.10
HGNC ID
HGNC:7907

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AN3CA Deletion: p.G1065AfsTer16 .
CAL62 SNV: p.N1107S .
COLO792 SNV: p.L110Ter .
CORL88 SNV: p.E489G .
DU145 SNV: p.G238Ter .
HCT116 SNV: p.Y1178C .
KPNYN SNV: p.V81G .
MFE319 SNV: p.S422N .
NCIH1792 SNV: p.P342T .
NCIH2172 SNV: p.D640H .
PF382 SNV: p.R756Q .
SSP25 SNV: p.M635L .
TE8 SNV: p.K446N .
TF1 SNV: p.R47Q .
TOV21G SNV: p.K425R .
YSCCC SNV: p.K190N .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C933(2.31); C941(2.31)  LDD0080  [1]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C741(1.06)  LDD0812  [1]
 LDCM0215  AC10 HEK-293T C738(0.84); C741(0.97)  LDD0813  [1]
 LDCM0216  AC100 HEK-293T C738(1.35); C741(1.07)  LDD0814  [1]
 LDCM0217  AC101 HEK-293T C738(1.32); C741(0.94)  LDD0815  [1]
 LDCM0218  AC102 HEK-293T C738(1.38); C741(0.98)  LDD0816  [1]
 LDCM0219  AC103 HEK-293T C738(1.20); C741(0.91)  LDD0817  [1]
 LDCM0220  AC104 HEK-293T C738(1.32); C741(1.04)  LDD0818  [1]
 LDCM0221  AC105 HEK-293T C738(1.37); C741(1.12)  LDD0819  [1]
 LDCM0222  AC106 HEK-293T C738(1.28); C741(1.17)  LDD0820  [1]
 LDCM0223  AC107 HEK-293T C738(1.21); C741(1.02)  LDD0821  [1]
 LDCM0224  AC108 HEK-293T C738(1.59); C741(1.00)  LDD0822  [1]
 LDCM0225  AC109 HEK-293T C738(1.24); C741(1.03)  LDD0823  [1]
 LDCM0226  AC11 HEK-293T C738(0.97); C741(0.99)  LDD0824  [1]
 LDCM0227  AC110 HEK-293T C738(1.53); C741(1.22)  LDD0825  [1]
 LDCM0228  AC111 HEK-293T C738(1.78); C741(1.30)  LDD0826  [1]
 LDCM0229  AC112 HEK-293T C738(1.83); C741(1.18)  LDD0827  [1]
 LDCM0230  AC113 HEK-293T C738(1.05); C741(0.90)  LDD0828  [1]
 LDCM0231  AC114 HEK-293T C738(0.76); C741(0.78)  LDD0829  [1]
 LDCM0232  AC115 HEK-293T C738(0.78); C741(0.81)  LDD0830  [1]
 LDCM0233  AC116 HEK-293T C738(1.18); C741(1.03)  LDD0831  [1]
 LDCM0234  AC117 HEK-293T C738(1.09); C741(0.86)  LDD0832  [1]
 LDCM0235  AC118 HEK-293T C738(1.21); C741(1.20)  LDD0833  [1]
 LDCM0236  AC119 HEK-293T C738(1.16); C741(0.87)  LDD0834  [1]
 LDCM0237  AC12 HEK-293T C738(0.92); C741(1.06)  LDD0835  [1]
 LDCM0238  AC120 HEK-293T C738(1.03); C741(0.93)  LDD0836  [1]
 LDCM0239  AC121 HEK-293T C738(1.50); C741(1.09)  LDD0837  [1]
 LDCM0240  AC122 HEK-293T C738(1.35); C741(0.90)  LDD0838  [1]
 LDCM0241  AC123 HEK-293T C738(1.26); C741(0.91)  LDD0839  [1]
 LDCM0242  AC124 HEK-293T C738(1.35); C741(0.82)  LDD0840  [1]
 LDCM0243  AC125 HEK-293T C738(1.08); C741(0.90)  LDD0841  [1]
 LDCM0244  AC126 HEK-293T C738(1.53); C741(0.97)  LDD0842  [1]
 LDCM0245  AC127 HEK-293T C738(1.32); C741(1.02)  LDD0843  [1]
 LDCM0246  AC128 HEK-293T C741(0.96)  LDD0844  [1]
 LDCM0247  AC129 HEK-293T C741(0.89)  LDD0845  [1]
 LDCM0249  AC130 HEK-293T C741(0.88)  LDD0847  [1]
 LDCM0250  AC131 HEK-293T C741(0.92)  LDD0848  [1]
 LDCM0251  AC132 HEK-293T C741(0.99)  LDD0849  [1]
 LDCM0252  AC133 HEK-293T C741(1.08)  LDD0850  [1]
 LDCM0253  AC134 HEK-293T C741(0.94)  LDD0851  [1]
 LDCM0254  AC135 HEK-293T C741(1.09)  LDD0852  [1]
 LDCM0255  AC136 HEK-293T C741(1.01)  LDD0853  [1]
 LDCM0256  AC137 HEK-293T C741(1.17)  LDD0854  [1]
 LDCM0257  AC138 HEK-293T C741(1.35)  LDD0855  [1]
 LDCM0258  AC139 HEK-293T C741(1.13)  LDD0856  [1]
 LDCM0259  AC14 HEK-293T C738(1.04); C741(1.01)  LDD0857  [1]
 LDCM0260  AC140 HEK-293T C741(1.03)  LDD0858  [1]
 LDCM0261  AC141 HEK-293T C741(1.16)  LDD0859  [1]
 LDCM0262  AC142 HEK-293T C741(0.97)  LDD0860  [1]
 LDCM0263  AC143 HEK-293T C741(1.16)  LDD0861  [1]
 LDCM0264  AC144 HEK-293T C741(1.22)  LDD0862  [1]
 LDCM0265  AC145 HEK-293T C741(1.35)  LDD0863  [1]
 LDCM0266  AC146 HEK-293T C741(1.37)  LDD0864  [1]
 LDCM0267  AC147 HEK-293T C741(1.37)  LDD0865  [1]
 LDCM0268  AC148 HEK-293T C741(1.31)  LDD0866  [1]
 LDCM0269  AC149 HEK-293T C741(0.87)  LDD0867  [1]
 LDCM0270  AC15 HEK-293T C738(0.94); C741(0.93)  LDD0868  [1]
 LDCM0271  AC150 HEK-293T C741(1.09)  LDD0869  [1]
 LDCM0272  AC151 HEK-293T C741(1.11)  LDD0870  [1]
 LDCM0273  AC152 HEK-293T C741(1.13)  LDD0871  [1]
 LDCM0274  AC153 HEK-293T C741(1.19)  LDD0872  [1]
 LDCM0621  AC154 HEK-293T C741(1.23)  LDD2162  [1]
 LDCM0622  AC155 HEK-293T C741(0.88)  LDD2163  [1]
 LDCM0623  AC156 HEK-293T C741(1.06)  LDD2164  [1]
 LDCM0624  AC157 HEK-293T C741(1.16)  LDD2165  [1]
 LDCM0276  AC17 HEK-293T C741(0.62)  LDD0874  [1]
 LDCM0277  AC18 HEK-293T C741(0.66)  LDD0875  [1]
 LDCM0278  AC19 HEK-293T C741(0.63)  LDD0876  [1]
 LDCM0279  AC2 HEK-293T C741(0.87)  LDD0877  [1]
 LDCM0280  AC20 HEK-293T C741(0.64)  LDD0878  [1]
 LDCM0281  AC21 HEK-293T C741(0.73)  LDD0879  [1]
 LDCM0282  AC22 HEK-293T C741(0.41)  LDD0880  [1]
 LDCM0283  AC23 HEK-293T C741(0.52)  LDD0881  [1]
 LDCM0284  AC24 HEK-293T C741(0.64)  LDD0882  [1]
 LDCM0285  AC25 HEK-293T C738(1.05); C741(0.82)  LDD0883  [1]
 LDCM0286  AC26 HEK-293T C738(1.19); C741(0.78)  LDD0884  [1]
 LDCM0287  AC27 HEK-293T C738(1.30); C741(0.76)  LDD0885  [1]
 LDCM0288  AC28 HEK-293T C738(0.89); C741(0.98)  LDD0886  [1]
 LDCM0289  AC29 HEK-293T C738(1.19); C741(0.68)  LDD0887  [1]
 LDCM0290  AC3 HEK-293T C741(0.95)  LDD0888  [1]
 LDCM0291  AC30 HEK-293T C738(1.30); C741(0.62)  LDD0889  [1]
 LDCM0292  AC31 HEK-293T C738(1.03); C741(0.83)  LDD0890  [1]
 LDCM0293  AC32 HEK-293T C738(1.31); C741(0.77)  LDD0891  [1]
 LDCM0294  AC33 HEK-293T C738(1.04); C741(0.62)  LDD0892  [1]
 LDCM0295  AC34 HEK-293T C738(0.96); C741(0.65)  LDD0893  [1]
 LDCM0296  AC35 HEK-293T C741(1.05)  LDD0894  [1]
 LDCM0297  AC36 HEK-293T C741(1.01)  LDD0895  [1]
 LDCM0298  AC37 HEK-293T C741(1.01)  LDD0896  [1]
 LDCM0299  AC38 HEK-293T C741(0.86)  LDD0897  [1]
 LDCM0300  AC39 HEK-293T C741(0.95)  LDD0898  [1]
 LDCM0301  AC4 HEK-293T C741(1.05)  LDD0899  [1]
 LDCM0302  AC40 HEK-293T C741(0.96)  LDD0900  [1]
 LDCM0303  AC41 HEK-293T C741(1.17)  LDD0901  [1]
 LDCM0304  AC42 HEK-293T C741(1.03)  LDD0902  [1]
 LDCM0305  AC43 HEK-293T C741(0.95)  LDD0903  [1]
 LDCM0306  AC44 HEK-293T C741(0.99)  LDD0904  [1]
 LDCM0307  AC45 HEK-293T C741(1.03)  LDD0905  [1]
 LDCM0308  AC46 HEK-293T C738(1.07); C741(1.09)  LDD0906  [1]
 LDCM0309  AC47 HEK-293T C738(1.17); C741(1.03)  LDD0907  [1]
 LDCM0310  AC48 HEK-293T C738(0.75); C741(0.78)  LDD0908  [1]
 LDCM0311  AC49 HEK-293T C738(1.02); C741(0.88)  LDD0909  [1]
 LDCM0312  AC5 HEK-293T C741(0.83)  LDD0910  [1]
 LDCM0313  AC50 HEK-293T C738(0.85); C741(0.80)  LDD0911  [1]
 LDCM0314  AC51 HEK-293T C738(1.00); C741(0.95)  LDD0912  [1]
 LDCM0315  AC52 HEK-293T C738(1.01); C741(0.88)  LDD0913  [1]
 LDCM0316  AC53 HEK-293T C738(0.66); C741(0.77)  LDD0914  [1]
 LDCM0317  AC54 HEK-293T C738(1.27); C741(1.03)  LDD0915  [1]
 LDCM0318  AC55 HEK-293T C738(0.83); C741(0.85)  LDD0916  [1]
 LDCM0319  AC56 HEK-293T C738(1.14); C741(0.98)  LDD0917  [1]
 LDCM0320  AC57 HEK-293T C741(1.01)  LDD0918  [1]
 LDCM0321  AC58 HEK-293T C741(0.76)  LDD0919  [1]
 LDCM0322  AC59 HEK-293T C741(1.39)  LDD0920  [1]
 LDCM0323  AC6 HEK-293T C738(1.05); C741(1.14)  LDD0921  [1]
 LDCM0324  AC60 HEK-293T C741(0.86)  LDD0922  [1]
 LDCM0325  AC61 HEK-293T C741(1.14)  LDD0923  [1]
 LDCM0326  AC62 HEK-293T C741(0.86)  LDD0924  [1]
 LDCM0327  AC63 HEK-293T C741(0.79)  LDD0925  [1]
 LDCM0328  AC64 HEK-293T C741(1.02)  LDD0926  [1]
 LDCM0329  AC65 HEK-293T C741(0.78)  LDD0927  [1]
 LDCM0330  AC66 HEK-293T C741(0.62)  LDD0928  [1]
 LDCM0331  AC67 HEK-293T C741(0.84)  LDD0929  [1]
 LDCM0332  AC68 HEK-293T C738(0.43); C741(0.95)  LDD0930  [1]
 LDCM0333  AC69 HEK-293T C738(0.63); C741(0.95)  LDD0931  [1]
 LDCM0334  AC7 HEK-293T C738(1.05); C741(1.01)  LDD0932  [1]
 LDCM0335  AC70 HEK-293T C738(0.78); C741(0.91)  LDD0933  [1]
 LDCM0336  AC71 HEK-293T C738(20.00); C741(1.06)  LDD0934  [1]
 LDCM0337  AC72 HEK-293T C738(0.49); C741(0.98)  LDD0935  [1]
 LDCM0338  AC73 HEK-293T C738(0.72); C741(1.06)  LDD0936  [1]
 LDCM0339  AC74 HEK-293T C738(0.72); C741(1.53)  LDD0937  [1]
 LDCM0340  AC75 HEK-293T C738(0.57); C741(0.88)  LDD0938  [1]
 LDCM0341  AC76 HEK-293T C738(0.56); C741(1.13)  LDD0939  [1]
 LDCM0342  AC77 HEK-293T C738(0.52); C741(0.92)  LDD0940  [1]
 LDCM0343  AC78 HEK-293T C738(0.54); C741(0.90)  LDD0941  [1]
 LDCM0344  AC79 HEK-293T C738(0.83); C741(1.01)  LDD0942  [1]
 LDCM0345  AC8 HEK-293T C738(0.91); C741(1.02)  LDD0943  [1]
 LDCM0346  AC80 HEK-293T C738(0.99); C741(0.95)  LDD0944  [1]
 LDCM0347  AC81 HEK-293T C738(0.53); C741(0.93)  LDD0945  [1]
 LDCM0348  AC82 HEK-293T C738(0.74); C741(0.91)  LDD0946  [1]
 LDCM0349  AC83 HEK-293T C738(0.95); C741(0.74)  LDD0947  [1]
 LDCM0350  AC84 HEK-293T C738(0.82); C741(0.41)  LDD0948  [1]
 LDCM0351  AC85 HEK-293T C738(1.14); C741(0.44)  LDD0949  [1]
 LDCM0352  AC86 HEK-293T C738(1.34); C741(0.45)  LDD0950  [1]
 LDCM0353  AC87 HEK-293T C738(1.43); C741(0.85)  LDD0951  [1]
 LDCM0354  AC88 HEK-293T C738(1.29); C741(0.78)  LDD0952  [1]
 LDCM0355  AC89 HEK-293T C738(1.17); C741(0.68)  LDD0953  [1]
 LDCM0357  AC90 HEK-293T C738(1.30); C741(0.46)  LDD0955  [1]
 LDCM0358  AC91 HEK-293T C738(1.42); C741(0.59)  LDD0956  [1]
 LDCM0359  AC92 HEK-293T C738(1.33); C741(0.49)  LDD0957  [1]
 LDCM0360  AC93 HEK-293T C738(1.08); C741(0.92)  LDD0958  [1]
 LDCM0361  AC94 HEK-293T C738(1.34); C741(0.64)  LDD0959  [1]
 LDCM0362  AC95 HEK-293T C738(1.37); C741(0.49)  LDD0960  [1]
 LDCM0363  AC96 HEK-293T C738(1.17); C741(0.53)  LDD0961  [1]
 LDCM0364  AC97 HEK-293T C738(2.45); C741(0.65)  LDD0962  [1]
 LDCM0365  AC98 HEK-293T C738(1.19); C741(1.11)  LDD0963  [1]
 LDCM0366  AC99 HEK-293T C738(1.35); C741(1.03)  LDD0964  [1]
 LDCM0248  AKOS034007472 HEK-293T C738(0.93); C741(1.02)  LDD0846  [1]
 LDCM0356  AKOS034007680 HEK-293T C738(1.41); C741(1.20)  LDD0954  [1]
 LDCM0275  AKOS034007705 HEK-293T C738(0.94); C741(0.91)  LDD0873  [1]
 LDCM0367  CL1 HEK-293T C741(0.81)  LDD0965  [1]
 LDCM0368  CL10 HEK-293T C741(1.03)  LDD0966  [1]
 LDCM0369  CL100 HEK-293T C741(0.77)  LDD0967  [1]
 LDCM0370  CL101 HEK-293T C738(1.30); C741(1.05)  LDD0968  [1]
 LDCM0371  CL102 HEK-293T C738(1.07); C741(1.00)  LDD0969  [1]
 LDCM0372  CL103 HEK-293T C738(0.91); C741(0.97)  LDD0970  [1]
 LDCM0373  CL104 HEK-293T C738(1.04); C741(1.01)  LDD0971  [1]
 LDCM0374  CL105 HEK-293T C741(0.58)  LDD0972  [1]
 LDCM0375  CL106 HEK-293T C741(0.58)  LDD0973  [1]
 LDCM0376  CL107 HEK-293T C741(0.91)  LDD0974  [1]
 LDCM0377  CL108 HEK-293T C741(0.68)  LDD0975  [1]
 LDCM0378  CL109 HEK-293T C741(0.47)  LDD0976  [1]
 LDCM0379  CL11 HEK-293T C741(1.13)  LDD0977  [1]
 LDCM0380  CL110 HEK-293T C741(0.48)  LDD0978  [1]
 LDCM0381  CL111 HEK-293T C741(0.62)  LDD0979  [1]
 LDCM0382  CL112 HEK-293T C738(1.15); C741(0.74)  LDD0980  [1]
 LDCM0383  CL113 HEK-293T C738(1.08); C741(0.82)  LDD0981  [1]
 LDCM0384  CL114 HEK-293T C738(1.42); C741(0.75)  LDD0982  [1]
 LDCM0385  CL115 HEK-293T C738(1.36); C741(0.62)  LDD0983  [1]
 LDCM0386  CL116 HEK-293T C738(1.01); C741(0.69)  LDD0984  [1]
 LDCM0387  CL117 HEK-293T C741(0.90)  LDD0985  [1]
 LDCM0388  CL118 HEK-293T C741(0.99)  LDD0986  [1]
 LDCM0389  CL119 HEK-293T C741(0.99)  LDD0987  [1]
 LDCM0390  CL12 HEK-293T C741(0.77)  LDD0988  [1]
 LDCM0391  CL120 HEK-293T C741(1.11)  LDD0989  [1]
 LDCM0392  CL121 HEK-293T C738(0.65); C741(0.74)  LDD0990  [1]
 LDCM0393  CL122 HEK-293T C738(0.85); C741(0.76)  LDD0991  [1]
 LDCM0394  CL123 HEK-293T C738(0.97); C741(0.89)  LDD0992  [1]
 LDCM0395  CL124 HEK-293T C738(1.17); C741(0.98)  LDD0993  [1]
 LDCM0396  CL125 HEK-293T C741(0.93)  LDD0994  [1]
 LDCM0397  CL126 HEK-293T C741(1.37)  LDD0995  [1]
 LDCM0398  CL127 HEK-293T C741(0.99)  LDD0996  [1]
 LDCM0399  CL128 HEK-293T C741(0.80)  LDD0997  [1]
 LDCM0400  CL13 HEK-293T C741(0.82)  LDD0998  [1]
 LDCM0401  CL14 HEK-293T C741(0.68)  LDD0999  [1]
 LDCM0402  CL15 HEK-293T C741(0.79)  LDD1000  [1]
 LDCM0403  CL16 HEK-293T C741(1.33)  LDD1001  [1]
 LDCM0404  CL17 HEK-293T C741(0.79)  LDD1002  [1]
 LDCM0405  CL18 HEK-293T C741(1.02)  LDD1003  [1]
 LDCM0406  CL19 HEK-293T C741(1.11)  LDD1004  [1]
 LDCM0407  CL2 HEK-293T C741(0.82)  LDD1005  [1]
 LDCM0408  CL20 HEK-293T C741(1.17)  LDD1006  [1]
 LDCM0409  CL21 HEK-293T C741(1.05)  LDD1007  [1]
 LDCM0410  CL22 HEK-293T C741(0.93)  LDD1008  [1]
 LDCM0411  CL23 HEK-293T C741(1.14)  LDD1009  [1]
 LDCM0412  CL24 HEK-293T C741(1.08)  LDD1010  [1]
 LDCM0413  CL25 HEK-293T C741(0.96)  LDD1011  [1]
 LDCM0414  CL26 HEK-293T C741(1.51)  LDD1012  [1]
 LDCM0415  CL27 HEK-293T C741(1.04)  LDD1013  [1]
 LDCM0416  CL28 HEK-293T C741(0.81)  LDD1014  [1]
 LDCM0417  CL29 HEK-293T C741(0.95)  LDD1015  [1]
 LDCM0418  CL3 HEK-293T C741(1.10)  LDD1016  [1]
 LDCM0419  CL30 HEK-293T C741(1.05)  LDD1017  [1]
 LDCM0420  CL31 PaTu 8988t C810(0.69); C816(0.69); C1134(0.96); C1145(0.96)  LDD1299  [1]
 LDCM0421  CL32 PaTu 8988t C810(0.74); C816(0.74); C1134(0.67); C1145(0.67)  LDD1300  [1]
 LDCM0422  CL33 PaTu 8988t C810(0.62); C816(0.62); C1134(0.71); C1145(0.71)  LDD1301  [1]
 LDCM0423  CL34 PaTu 8988t C810(0.75); C816(0.75); C1134(0.62); C1145(0.62)  LDD1302  [1]
 LDCM0424  CL35 PaTu 8988t C810(0.76); C816(0.76); C1134(0.62); C1145(0.62)  LDD1303  [1]
 LDCM0425  CL36 PaTu 8988t C810(0.61); C816(0.61); C1134(0.65); C1145(0.65)  LDD1304  [1]
 LDCM0426  CL37 PaTu 8988t C810(0.87); C816(0.87); C1134(0.61); C1145(0.61)  LDD1305  [1]
 LDCM0428  CL39 PaTu 8988t C810(0.67); C816(0.67); C1134(0.66); C1145(0.66)  LDD1307  [1]
 LDCM0429  CL4 HEK-293T C741(0.95)  LDD1027  [1]
 LDCM0430  CL40 PaTu 8988t C810(0.65); C816(0.65); C1134(0.74); C1145(0.74)  LDD1309  [1]
 LDCM0431  CL41 PaTu 8988t C810(0.61); C816(0.61); C1134(0.63); C1145(0.63)  LDD1310  [1]
 LDCM0432  CL42 PaTu 8988t C810(0.75); C816(0.75); C1134(0.60); C1145(0.60)  LDD1311  [1]
 LDCM0433  CL43 PaTu 8988t C810(0.88); C816(0.88); C1134(0.75); C1145(0.75)  LDD1312  [1]
 LDCM0434  CL44 PaTu 8988t C810(0.66); C816(0.66); C1134(0.61); C1145(0.61)  LDD1313  [1]
 LDCM0435  CL45 PaTu 8988t C810(0.63); C816(0.63); C1134(0.60); C1145(0.60)  LDD1314  [1]
 LDCM0436  CL46 HEK-293T C741(1.07)  LDD1034  [1]
 LDCM0437  CL47 HEK-293T C741(1.03)  LDD1035  [1]
 LDCM0438  CL48 HEK-293T C741(1.09)  LDD1036  [1]
 LDCM0439  CL49 HEK-293T C741(0.96)  LDD1037  [1]
 LDCM0440  CL5 HEK-293T C741(0.80)  LDD1038  [1]
 LDCM0441  CL50 HEK-293T C741(1.30)  LDD1039  [1]
 LDCM0442  CL51 HEK-293T C741(1.06)  LDD1040  [1]
 LDCM0443  CL52 HEK-293T C741(1.04)  LDD1041  [1]
 LDCM0444  CL53 HEK-293T C741(1.08)  LDD1042  [1]
 LDCM0445  CL54 HEK-293T C741(1.22)  LDD1043  [1]
 LDCM0446  CL55 HEK-293T C741(1.02)  LDD1044  [1]
 LDCM0447  CL56 HEK-293T C741(1.18)  LDD1045  [1]
 LDCM0448  CL57 HEK-293T C741(0.93)  LDD1046  [1]
 LDCM0449  CL58 HEK-293T C741(1.13)  LDD1047  [1]
 LDCM0450  CL59 HEK-293T C741(1.01)  LDD1048  [1]
 LDCM0451  CL6 HEK-293T C741(0.75)  LDD1049  [1]
 LDCM0452  CL60 HEK-293T C741(1.10)  LDD1050  [1]
 LDCM0453  CL61 HEK-293T C741(1.20)  LDD1051  [1]
 LDCM0454  CL62 HEK-293T C741(0.72)  LDD1052  [1]
 LDCM0455  CL63 HEK-293T C741(0.91)  LDD1053  [1]
 LDCM0456  CL64 HEK-293T C741(1.33)  LDD1054  [1]
 LDCM0457  CL65 HEK-293T C741(0.90)  LDD1055  [1]
 LDCM0458  CL66 HEK-293T C741(0.83)  LDD1056  [1]
 LDCM0459  CL67 HEK-293T C741(0.96)  LDD1057  [1]
 LDCM0460  CL68 HEK-293T C741(0.91)  LDD1058  [1]
 LDCM0461  CL69 HEK-293T C741(0.77)  LDD1059  [1]
 LDCM0462  CL7 HEK-293T C741(0.99)  LDD1060  [1]
 LDCM0463  CL70 HEK-293T C741(0.88)  LDD1061  [1]
 LDCM0464  CL71 HEK-293T C741(0.79)  LDD1062  [1]
 LDCM0465  CL72 HEK-293T C741(1.01)  LDD1063  [1]
 LDCM0466  CL73 HEK-293T C741(0.88)  LDD1064  [1]
 LDCM0467  CL74 HEK-293T C741(0.96)  LDD1065  [1]
 LDCM0469  CL76 HEK-293T C738(1.14); C741(0.97)  LDD1067  [1]
 LDCM0470  CL77 HEK-293T C738(1.57); C741(1.13)  LDD1068  [1]
 LDCM0471  CL78 HEK-293T C738(0.95); C741(0.83)  LDD1069  [1]
 LDCM0472  CL79 HEK-293T C738(1.31); C741(0.89)  LDD1070  [1]
 LDCM0473  CL8 PaTu 8988t C738(0.97); C741(0.97); C933(0.63); C941(0.63)  LDD1352  [1]
 LDCM0474  CL80 HEK-293T C738(1.20); C741(0.91)  LDD1072  [1]
 LDCM0475  CL81 HEK-293T C738(1.07); C741(0.79)  LDD1073  [1]
 LDCM0476  CL82 HEK-293T C738(1.22); C741(0.95)  LDD1074  [1]
 LDCM0477  CL83 HEK-293T C738(1.15); C741(1.01)  LDD1075  [1]
 LDCM0478  CL84 HEK-293T C738(0.95); C741(0.82)  LDD1076  [1]
 LDCM0479  CL85 HEK-293T C738(0.96); C741(0.84)  LDD1077  [1]
 LDCM0480  CL86 HEK-293T C738(1.24); C741(0.86)  LDD1078  [1]
 LDCM0481  CL87 HEK-293T C738(1.09); C741(0.89)  LDD1079  [1]
 LDCM0482  CL88 HEK-293T C738(1.21); C741(0.87)  LDD1080  [1]
 LDCM0483  CL89 HEK-293T C738(1.14); C741(0.83)  LDD1081  [1]
 LDCM0484  CL9 PaTu 8988t C738(0.83); C741(0.83); C933(0.65); C941(0.65)  LDD1363  [1]
 LDCM0485  CL90 HEK-293T C738(2.11); C741(0.90)  LDD1083  [1]
 LDCM0486  CL91 HEK-293T C741(0.94)  LDD1084  [1]
 LDCM0487  CL92 HEK-293T C741(0.91)  LDD1085  [1]
 LDCM0488  CL93 HEK-293T C741(0.72)  LDD1086  [1]
 LDCM0489  CL94 HEK-293T C741(0.88)  LDD1087  [1]
 LDCM0490  CL95 HEK-293T C741(0.80)  LDD1088  [1]
 LDCM0491  CL96 HEK-293T C741(0.79)  LDD1089  [1]
 LDCM0492  CL97 HEK-293T C741(0.78)  LDD1090  [1]
 LDCM0493  CL98 HEK-293T C741(0.83)  LDD1091  [1]
 LDCM0494  CL99 HEK-293T C741(0.88)  LDD1092  [1]
 LDCM0468  Fragment33 HEK-293T C741(0.92)  LDD1066  [1]
 LDCM0427  Fragment51 PaTu 8988t C810(0.67); C816(0.67); C1134(0.75); C1145(0.75)  LDD1306  [1]
 LDCM0022  KB02 HCT 116 C933(2.31); C941(2.31)  LDD0080  [1]
 LDCM0023  KB03 HCT 116 C933(1.74); C941(1.74)  LDD0081  [1]
 LDCM0024  KB05 HCT 116 C933(6.17); C941(6.17)  LDD0082  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
RuvB-like 1 (RUVBL1) RuvB family Q9Y265
Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein unc-119 homolog A (UNC119) PDE6D/unc-119 family Q13432
Centrosomal protein of 164 kDa (CEP164) . Q9UPV0

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060