Details of the Target

General Information of Target

Target ID LDTP07322
Target Name Coiled-coil domain-containing protein 102B (CCDC102B)
Gene Name CCDC102B
Gene ID 79839
Synonyms
C18orf14; Coiled-coil domain-containing protein 102B
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MNLDSIHRLIEETQIFQMQQSSIKSRGDMVAPASPPRDTCNTCFPLHGLQSHAAHNFCAH
SYNTNKWDICEELRLRELEEVKARAAQMEKTMRWWSDCTANWREKWSKVRAERNSAREEG
RQLRIKLEMAMKELSTLKKKQSLPPQKEALEAKVTQDLKLPGFVEESCEHTDQFQLSSQM
HESIREYLVKRQFSTKEDTNNKEQGVVIDSLKLSEEMKPNLDGVDLFNNGGSGNGETKTG
LRLKAINLPLENEVTEISALQVHLDEFQKILWKEREMRTALEKEIERLESALSLWKWKYE
ELKESKPKNVKEFDILLGQHNDEMQELSGNIKEESKSQNSKDRVICELRAELERLQAENT
SEWDKREILEREKQGLERENRRLKIQVKEMEELLDKKNRLSANSQSPDFKMSQIDLQEKN
QELLNLQHAYYKLNRQYQANIAELTHANNRVDQNEAEVKKLRLRVEELKQGLNQKEDELD
DSLNQIRKLQRSLDEEKERNENLETELRHLQNW
Target Bioclass
Other
Subcellular location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole
Function
During interphase, forms fibers at the proximal ends of centrioles to maintain centrosome cohesion. During mitosis, dissociates from the centrosome following phosphorylation to allow centrosome separation. Contributes to CROCC/rootletin filament formation.
Uniprot ID
Q68D86
Ensemble ID
ENST00000360242.9
HGNC ID
HGNC:26295

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HDQP1 SNV: p.K273N .
K562 SNV: p.G375V .
MFE319 SNV: p.D415V .
NCIH2172 SNV: p.D222Y .
RPMI7951 SNV: p.E215K .
VCAP SNV: p.K419E .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C98(0.88)  LDD0531  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C98(0.88)  LDD0531  [1]
 LDCM0215  AC10 PaTu 8988t C98(1.24)  LDD1094  [1]
 LDCM0216  AC100 HEK-293T C98(0.93)  LDD0814  [1]
 LDCM0217  AC101 HEK-293T C98(0.82)  LDD0815  [1]
 LDCM0218  AC102 HEK-293T C98(0.86)  LDD0816  [1]
 LDCM0219  AC103 HEK-293T C98(0.88)  LDD0817  [1]
 LDCM0220  AC104 HEK-293T C98(1.01)  LDD0818  [1]
 LDCM0221  AC105 HEK-293T C98(1.07)  LDD0819  [1]
 LDCM0222  AC106 HEK-293T C98(0.94)  LDD0820  [1]
 LDCM0223  AC107 HEK-293T C98(0.78)  LDD0821  [1]
 LDCM0224  AC108 HEK-293T C98(1.00)  LDD0822  [1]
 LDCM0225  AC109 HEK-293T C98(0.94)  LDD0823  [1]
 LDCM0226  AC11 PaTu 8988t C98(1.27)  LDD1105  [1]
 LDCM0227  AC110 HEK-293T C98(0.86)  LDD0825  [1]
 LDCM0228  AC111 HEK-293T C98(1.01)  LDD0826  [1]
 LDCM0229  AC112 HEK-293T C98(0.90)  LDD0827  [1]
 LDCM0230  AC113 HCT 116 C98(1.04)  LDD0547  [1]
 LDCM0231  AC114 HCT 116 C98(1.26)  LDD0548  [1]
 LDCM0232  AC115 HCT 116 C98(1.34)  LDD0549  [1]
 LDCM0233  AC116 HCT 116 C98(1.37)  LDD0550  [1]
 LDCM0234  AC117 HCT 116 C98(1.32)  LDD0551  [1]
 LDCM0235  AC118 HCT 116 C98(1.20)  LDD0552  [1]
 LDCM0236  AC119 HCT 116 C98(1.30)  LDD0553  [1]
 LDCM0237  AC12 PaTu 8988t C98(1.20)  LDD1116  [1]
 LDCM0238  AC120 HCT 116 C98(1.15)  LDD0555  [1]
 LDCM0239  AC121 HCT 116 C98(1.01)  LDD0556  [1]
 LDCM0240  AC122 HCT 116 C98(1.23)  LDD0557  [1]
 LDCM0241  AC123 HCT 116 C98(1.00)  LDD0558  [1]
 LDCM0242  AC124 HCT 116 C98(1.17)  LDD0559  [1]
 LDCM0243  AC125 HCT 116 C98(1.09)  LDD0560  [1]
 LDCM0244  AC126 HCT 116 C98(1.29)  LDD0561  [1]
 LDCM0245  AC127 HCT 116 C98(1.27)  LDD0562  [1]
 LDCM0259  AC14 PaTu 8988t C98(0.87)  LDD1138  [1]
 LDCM0263  AC143 HCT 116 C98(1.18)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C98(1.25)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C98(1.08)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C98(1.35)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C98(1.42)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C98(1.91)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C98(1.42)  LDD0586  [1]
 LDCM0270  AC15 PaTu 8988t C98(0.99)  LDD1149  [1]
 LDCM0271  AC150 HCT 116 C98(1.15)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C98(1.05)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C98(1.33)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C98(1.88)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C98(1.47)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C98(1.40)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C98(1.02)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C98(1.09)  LDD2161  [1]
 LDCM0276  AC17 HEK-293T C98(1.24)  LDD0874  [1]
 LDCM0277  AC18 HEK-293T C98(1.15)  LDD0875  [1]
 LDCM0278  AC19 HEK-293T C98(1.05)  LDD0876  [1]
 LDCM0279  AC2 HCT 116 C98(0.92)  LDD0596  [1]
 LDCM0280  AC20 HEK-293T C98(1.01)  LDD0878  [1]
 LDCM0281  AC21 HEK-293T C98(1.05)  LDD0879  [1]
 LDCM0282  AC22 HEK-293T C98(1.05)  LDD0880  [1]
 LDCM0283  AC23 HEK-293T C98(1.05)  LDD0881  [1]
 LDCM0284  AC24 HEK-293T C98(1.08)  LDD0882  [1]
 LDCM0285  AC25 PaTu 8988t C98(1.65)  LDD1164  [1]
 LDCM0286  AC26 PaTu 8988t C98(1.30)  LDD1165  [1]
 LDCM0287  AC27 PaTu 8988t C98(1.09)  LDD1166  [1]
 LDCM0288  AC28 PaTu 8988t C98(1.80)  LDD1167  [1]
 LDCM0289  AC29 PaTu 8988t C98(1.39)  LDD1168  [1]
 LDCM0290  AC3 HCT 116 C98(0.91)  LDD0607  [1]
 LDCM0291  AC30 PaTu 8988t C98(1.50)  LDD1170  [1]
 LDCM0292  AC31 PaTu 8988t C98(1.25)  LDD1171  [1]
 LDCM0293  AC32 PaTu 8988t C98(1.22)  LDD1172  [1]
 LDCM0294  AC33 PaTu 8988t C98(1.95)  LDD1173  [1]
 LDCM0295  AC34 PaTu 8988t C98(1.31)  LDD1174  [1]
 LDCM0296  AC35 PaTu 8988t C98(1.31)  LDD1175  [1]
 LDCM0297  AC36 PaTu 8988t C98(1.35)  LDD1176  [1]
 LDCM0298  AC37 PaTu 8988t C98(1.47)  LDD1177  [1]
 LDCM0299  AC38 PaTu 8988t C98(1.43)  LDD1178  [1]
 LDCM0300  AC39 PaTu 8988t C98(1.85)  LDD1179  [1]
 LDCM0301  AC4 HCT 116 C98(1.53)  LDD0618  [1]
 LDCM0302  AC40 PaTu 8988t C98(1.94)  LDD1181  [1]
 LDCM0303  AC41 PaTu 8988t C98(1.32)  LDD1182  [1]
 LDCM0304  AC42 PaTu 8988t C98(1.36)  LDD1183  [1]
 LDCM0305  AC43 PaTu 8988t C98(1.31)  LDD1184  [1]
 LDCM0306  AC44 PaTu 8988t C98(1.93)  LDD1185  [1]
 LDCM0307  AC45 PaTu 8988t C98(1.47)  LDD1186  [1]
 LDCM0308  AC46 HEK-293T C98(0.85)  LDD0906  [1]
 LDCM0309  AC47 HEK-293T C98(0.84)  LDD0907  [1]
 LDCM0310  AC48 HEK-293T C98(0.80)  LDD0908  [1]
 LDCM0311  AC49 HEK-293T C98(1.01)  LDD0909  [1]
 LDCM0312  AC5 HCT 116 C98(0.93)  LDD0629  [1]
 LDCM0313  AC50 HEK-293T C98(0.94)  LDD0911  [1]
 LDCM0314  AC51 HEK-293T C98(1.02)  LDD0912  [1]
 LDCM0315  AC52 HEK-293T C98(1.02)  LDD0913  [1]
 LDCM0316  AC53 HEK-293T C98(1.10)  LDD0914  [1]
 LDCM0317  AC54 HEK-293T C98(1.09)  LDD0915  [1]
 LDCM0318  AC55 HEK-293T C98(0.96)  LDD0916  [1]
 LDCM0319  AC56 HEK-293T C98(0.85)  LDD0917  [1]
 LDCM0320  AC57 HEK-293T C98(1.04)  LDD0918  [1]
 LDCM0321  AC58 HEK-293T C98(1.09)  LDD0919  [1]
 LDCM0322  AC59 HEK-293T C98(1.05)  LDD0920  [1]
 LDCM0323  AC6 PaTu 8988t C98(1.05)  LDD1202  [1]
 LDCM0324  AC60 HEK-293T C98(1.23)  LDD0922  [1]
 LDCM0325  AC61 HEK-293T C98(1.12)  LDD0923  [1]
 LDCM0326  AC62 HEK-293T C98(1.21)  LDD0924  [1]
 LDCM0327  AC63 HEK-293T C98(1.06)  LDD0925  [1]
 LDCM0328  AC64 HEK-293T C98(1.07)  LDD0926  [1]
 LDCM0329  AC65 HEK-293T C98(1.04)  LDD0927  [1]
 LDCM0330  AC66 HEK-293T C98(1.09)  LDD0928  [1]
 LDCM0331  AC67 HEK-293T C98(1.03)  LDD0929  [1]
 LDCM0332  AC68 HCT 116 C98(1.07)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C98(1.07)  LDD0650  [1]
 LDCM0334  AC7 PaTu 8988t C98(1.05)  LDD1213  [1]
 LDCM0335  AC70 HCT 116 C98(1.10)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C98(0.96)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C98(1.22)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C98(1.70)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C98(1.68)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C98(1.75)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C98(1.19)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C98(1.18)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C98(1.04)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C98(1.04)  LDD0661  [1]
 LDCM0345  AC8 PaTu 8988t C98(0.90)  LDD1224  [1]
 LDCM0346  AC80 HCT 116 C98(1.13)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C98(0.80)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C98(1.87)  LDD0665  [1]
 LDCM0349  AC83 HCT 116 C98(1.76)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C98(1.45)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C98(1.29)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C98(1.18)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C98(0.93)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C98(1.16)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C98(1.54)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C98(0.87)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C98(1.79)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C98(2.16)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C98(1.21)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C98(0.99)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C98(1.15)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C98(1.40)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C98(1.57)  LDD0681  [1]
 LDCM0365  AC98 HEK-293T C98(0.85)  LDD0963  [1]
 LDCM0366  AC99 HEK-293T C98(1.01)  LDD0964  [1]
 LDCM0248  AKOS034007472 PaTu 8988t C98(0.98)  LDD1127  [1]
 LDCM0356  AKOS034007680 PaTu 8988t C98(1.47)  LDD1235  [1]
 LDCM0275  AKOS034007705 PaTu 8988t C98(1.35)  LDD1154  [1]
 LDCM0367  CL1 HCT 116 C98(1.06)  LDD0684  [1]
 LDCM0368  CL10 HCT 116 C98(1.74)  LDD0685  [1]
 LDCM0369  CL100 HCT 116 C98(0.94)  LDD0686  [1]
 LDCM0370  CL101 PaTu 8988t C98(1.11)  LDD1249  [1]
 LDCM0371  CL102 PaTu 8988t C98(1.22)  LDD1250  [1]
 LDCM0372  CL103 PaTu 8988t C98(1.27)  LDD1251  [1]
 LDCM0373  CL104 PaTu 8988t C98(1.11)  LDD1252  [1]
 LDCM0374  CL105 HEK-293T C98(1.06)  LDD0972  [1]
 LDCM0375  CL106 HEK-293T C98(1.13)  LDD0973  [1]
 LDCM0376  CL107 HEK-293T C98(1.00)  LDD0974  [1]
 LDCM0377  CL108 HEK-293T C98(1.01)  LDD0975  [1]
 LDCM0378  CL109 HEK-293T C98(1.14)  LDD0976  [1]
 LDCM0379  CL11 HCT 116 C98(2.08)  LDD0696  [1]
 LDCM0380  CL110 HEK-293T C98(1.17)  LDD0978  [1]
 LDCM0381  CL111 HEK-293T C98(1.08)  LDD0979  [1]
 LDCM0382  CL112 PaTu 8988t C98(1.15)  LDD1261  [1]
 LDCM0383  CL113 PaTu 8988t C98(1.24)  LDD1262  [1]
 LDCM0384  CL114 PaTu 8988t C98(1.45)  LDD1263  [1]
 LDCM0385  CL115 PaTu 8988t C98(1.25)  LDD1264  [1]
 LDCM0386  CL116 PaTu 8988t C98(1.05)  LDD1265  [1]
 LDCM0387  CL117 PaTu 8988t C98(1.30)  LDD1266  [1]
 LDCM0388  CL118 PaTu 8988t C98(1.36)  LDD1267  [1]
 LDCM0389  CL119 PaTu 8988t C98(1.31)  LDD1268  [1]
 LDCM0390  CL12 HCT 116 C98(1.87)  LDD0707  [1]
 LDCM0391  CL120 PaTu 8988t C98(1.69)  LDD1270  [1]
 LDCM0392  CL121 HEK-293T C98(0.81)  LDD0990  [1]
 LDCM0393  CL122 HEK-293T C98(0.97)  LDD0991  [1]
 LDCM0394  CL123 HEK-293T C98(0.98)  LDD0992  [1]
 LDCM0395  CL124 HEK-293T C98(0.86)  LDD0993  [1]
 LDCM0396  CL125 HEK-293T C98(1.00)  LDD0994  [1]
 LDCM0397  CL126 HEK-293T C98(0.98)  LDD0995  [1]
 LDCM0398  CL127 HEK-293T C98(1.25)  LDD0996  [1]
 LDCM0399  CL128 HEK-293T C98(1.15)  LDD0997  [1]
 LDCM0400  CL13 HCT 116 C98(1.39)  LDD0717  [1]
 LDCM0401  CL14 HCT 116 C98(1.40)  LDD0718  [1]
 LDCM0402  CL15 HCT 116 C98(1.84)  LDD0719  [1]
 LDCM0403  CL16 HEK-293T C98(1.28)  LDD1001  [1]
 LDCM0404  CL17 HEK-293T C98(0.98)  LDD1002  [1]
 LDCM0405  CL18 HEK-293T C98(1.25)  LDD1003  [1]
 LDCM0406  CL19 HEK-293T C98(0.93)  LDD1004  [1]
 LDCM0407  CL2 HCT 116 C98(1.05)  LDD0724  [1]
 LDCM0408  CL20 HEK-293T C98(1.32)  LDD1006  [1]
 LDCM0409  CL21 HEK-293T C98(0.79)  LDD1007  [1]
 LDCM0410  CL22 HEK-293T C98(1.34)  LDD1008  [1]
 LDCM0411  CL23 HEK-293T C98(1.30)  LDD1009  [1]
 LDCM0412  CL24 HEK-293T C98(1.66)  LDD1010  [1]
 LDCM0413  CL25 HEK-293T C98(1.20)  LDD1011  [1]
 LDCM0414  CL26 HEK-293T C98(1.23)  LDD1012  [1]
 LDCM0415  CL27 HEK-293T C98(1.01)  LDD1013  [1]
 LDCM0416  CL28 HEK-293T C98(1.03)  LDD1014  [1]
 LDCM0417  CL29 HEK-293T C98(1.10)  LDD1015  [1]
 LDCM0418  CL3 HCT 116 C98(1.16)  LDD0735  [1]
 LDCM0419  CL30 HEK-293T C98(0.93)  LDD1017  [1]
 LDCM0420  CL31 HEK-293T C98(1.07)  LDD1018  [1]
 LDCM0421  CL32 HEK-293T C98(1.05)  LDD1019  [1]
 LDCM0422  CL33 HEK-293T C98(1.13)  LDD1020  [1]
 LDCM0423  CL34 HEK-293T C98(1.10)  LDD1021  [1]
 LDCM0424  CL35 HEK-293T C98(1.11)  LDD1022  [1]
 LDCM0425  CL36 HEK-293T C98(1.05)  LDD1023  [1]
 LDCM0426  CL37 HEK-293T C98(1.11)  LDD1024  [1]
 LDCM0428  CL39 HEK-293T C98(1.19)  LDD1026  [1]
 LDCM0429  CL4 HCT 116 C98(0.91)  LDD0746  [1]
 LDCM0430  CL40 HEK-293T C98(1.10)  LDD1028  [1]
 LDCM0431  CL41 HEK-293T C98(1.08)  LDD1029  [1]
 LDCM0432  CL42 HEK-293T C98(1.10)  LDD1030  [1]
 LDCM0433  CL43 HEK-293T C98(1.10)  LDD1031  [1]
 LDCM0434  CL44 HEK-293T C98(1.04)  LDD1032  [1]
 LDCM0435  CL45 HEK-293T C98(1.08)  LDD1033  [1]
 LDCM0436  CL46 HEK-293T C98(1.21)  LDD1034  [1]
 LDCM0437  CL47 HEK-293T C98(1.20)  LDD1035  [1]
 LDCM0438  CL48 HEK-293T C98(1.02)  LDD1036  [1]
 LDCM0439  CL49 HEK-293T C98(0.92)  LDD1037  [1]
 LDCM0440  CL5 HCT 116 C98(1.53)  LDD0757  [1]
 LDCM0441  CL50 HEK-293T C98(0.85)  LDD1039  [1]
 LDCM0442  CL51 HEK-293T C98(1.08)  LDD1040  [1]
 LDCM0443  CL52 HEK-293T C98(0.73)  LDD1041  [1]
 LDCM0444  CL53 HEK-293T C98(0.96)  LDD1042  [1]
 LDCM0445  CL54 HEK-293T C98(1.03)  LDD1043  [1]
 LDCM0446  CL55 HEK-293T C98(1.24)  LDD1044  [1]
 LDCM0447  CL56 HEK-293T C98(0.96)  LDD1045  [1]
 LDCM0448  CL57 HEK-293T C98(1.07)  LDD1046  [1]
 LDCM0449  CL58 HEK-293T C98(1.21)  LDD1047  [1]
 LDCM0450  CL59 HEK-293T C98(1.20)  LDD1048  [1]
 LDCM0451  CL6 HCT 116 C98(1.40)  LDD0768  [1]
 LDCM0452  CL60 HEK-293T C98(1.26)  LDD1050  [1]
 LDCM0453  CL61 PaTu 8988t C98(1.11)  LDD1332  [1]
 LDCM0454  CL62 PaTu 8988t C98(0.86)  LDD1333  [1]
 LDCM0455  CL63 PaTu 8988t C98(0.86)  LDD1334  [1]
 LDCM0456  CL64 PaTu 8988t C98(0.90)  LDD1335  [1]
 LDCM0457  CL65 PaTu 8988t C98(1.02)  LDD1336  [1]
 LDCM0458  CL66 PaTu 8988t C98(1.03)  LDD1337  [1]
 LDCM0459  CL67 PaTu 8988t C98(1.36)  LDD1338  [1]
 LDCM0460  CL68 PaTu 8988t C98(2.04)  LDD1339  [1]
 LDCM0461  CL69 PaTu 8988t C98(1.51)  LDD1340  [1]
 LDCM0462  CL7 HCT 116 C98(1.28)  LDD0779  [1]
 LDCM0463  CL70 PaTu 8988t C98(1.51)  LDD1342  [1]
 LDCM0464  CL71 PaTu 8988t C98(0.85)  LDD1343  [1]
 LDCM0465  CL72 PaTu 8988t C98(0.82)  LDD1344  [1]
 LDCM0466  CL73 PaTu 8988t C98(1.75)  LDD1345  [1]
 LDCM0467  CL74 PaTu 8988t C98(0.93)  LDD1346  [1]
 LDCM0469  CL76 PaTu 8988t C98(1.04)  LDD1348  [1]
 LDCM0470  CL77 PaTu 8988t C98(1.78)  LDD1349  [1]
 LDCM0471  CL78 PaTu 8988t C98(1.96)  LDD1350  [1]
 LDCM0472  CL79 PaTu 8988t C98(1.39)  LDD1351  [1]
 LDCM0473  CL8 HCT 116 C98(2.13)  LDD0790  [1]
 LDCM0474  CL80 PaTu 8988t C98(1.60)  LDD1353  [1]
 LDCM0475  CL81 PaTu 8988t C98(1.80)  LDD1354  [1]
 LDCM0476  CL82 PaTu 8988t C98(1.76)  LDD1355  [1]
 LDCM0477  CL83 PaTu 8988t C98(1.62)  LDD1356  [1]
 LDCM0478  CL84 PaTu 8988t C98(1.31)  LDD1357  [1]
 LDCM0479  CL85 PaTu 8988t C98(1.95)  LDD1358  [1]
 LDCM0480  CL86 PaTu 8988t C98(1.07)  LDD1359  [1]
 LDCM0481  CL87 PaTu 8988t C98(1.61)  LDD1360  [1]
 LDCM0482  CL88 PaTu 8988t C98(1.69)  LDD1361  [1]
 LDCM0483  CL89 PaTu 8988t C98(1.36)  LDD1362  [1]
 LDCM0484  CL9 HCT 116 C98(1.27)  LDD0801  [1]
 LDCM0485  CL90 PaTu 8988t C98(1.60)  LDD1364  [1]
 LDCM0486  CL91 HCT 116 C98(1.08)  LDD0803  [1]
 LDCM0487  CL92 HCT 116 C98(1.02)  LDD0804  [1]
 LDCM0488  CL93 HCT 116 C98(0.86)  LDD0805  [1]
 LDCM0489  CL94 HCT 116 C98(1.12)  LDD0806  [1]
 LDCM0490  CL95 HCT 116 C98(1.50)  LDD0807  [1]
 LDCM0491  CL96 HCT 116 C98(1.03)  LDD0808  [1]
 LDCM0492  CL97 HCT 116 C98(0.84)  LDD0809  [1]
 LDCM0493  CL98 HCT 116 C98(0.92)  LDD0810  [1]
 LDCM0494  CL99 HCT 116 C98(1.04)  LDD0811  [1]
 LDCM0468  Fragment33 PaTu 8988t C98(1.10)  LDD1347  [1]
 LDCM0427  Fragment51 HEK-293T C98(0.99)  LDD1025  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 22 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Maspardin (SPG21) AB hydrolase superfamily Q9NZD8
Adenylate kinase 8 (AK8) Adenylate kinase family Q96MA6
Fumarate hydratase, mitochondrial (FH) Class-II fumarase/aspartase family P07954
Peroxisomal bifunctional enzyme (EHHADH) Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase family Q08426
Ribonuclease P/MRP protein subunit POP5 (POP5) Eukaryotic/archaeal RNase P protein component 2 family Q969H6
NIF3-like protein 1 (NIF3L1) GTP cyclohydrolase I type 2/NIF3 family Q9GZT8
Protein mab-21-like 2 (MAB21L2) Mab-21 family Q9Y586
DNA replication licensing factor MCM7 (MCM7) MCM family P33993
Nucleoside diphosphate kinase, mitochondrial (NME4) NDK family O00746
Protein N-terminal glutamine amidohydrolase (NTAQ1) NTAQ1 family Q96HA8
Proteasome subunit alpha type-1 (PSMA1) Peptidase T1A family P25786
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) Phosphoglycerate mutase family Q16877
Cyclin-dependent kinase 18 (CDK18) CMGC Ser/Thr protein kinase family Q07002
Proto-oncogene serine/threonine-protein kinase mos (MOS) Ser/Thr protein kinase family P00540
E3 ubiquitin-protein ligase SH3RF2 (SH3RF2) SH3RF family Q8TEC5
ADP-ribosylation factor-like protein 4A (ARL4A) Arf family P40617
ADP-ribosylation factor-like protein 4D (ARL4D) Arf family P49703
GTP-binding protein GEM (GEM) RGK family P55040
Kinesin-like protein KIFC3 (KIFC3) Kinesin family Q9BVG8
Zinc finger protein RFP (TRIM27) TRIM/RBCC family P14373
E3 ubiquitin-protein ligase LNX (LNX1) . Q8TBB1
Tripartite motif-containing protein 54 (TRIM54) . Q9BYV2
Transporter and channel
Click To Hide/Show 8 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Flotillin-1 (FLOT1) Band 7/mec-2 family O75955
Voltage-dependent L-type calcium channel subunit beta-4 (CACNB4) Calcium channel beta subunit family O00305
Importin subunit alpha-4 (KPNA3) Importin alpha family O00505
Leucine zipper putative tumor suppressor 1 (LZTS1) LZTS family Q9Y250
Exocyst complex component 5 (EXOC5) SEC10 family O00471
SNARE-associated protein Snapin (SNAPIN) SNAPIN family O95295
Golgi-associated PDZ and coiled-coil motif-containing protein (GOPC) . Q9HD26
Syntenin-1 (SDCBP) . O00560
Transcription factor
Click To Hide/Show 11 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
REST corepressor 3 (RCOR3) CoREST family Q9P2K3
Zinc finger protein Aiolos (IKZF3) Ikaros C2H2-type zinc-finger protein family Q9UKT9
Zinc finger protein 20 (ZNF20) Krueppel C2H2-type zinc-finger protein family P17024
Zinc finger protein 572 (ZNF572) Krueppel C2H2-type zinc-finger protein family Q7Z3I7
Zinc finger protein 620 (ZNF620) Krueppel C2H2-type zinc-finger protein family Q6ZNG0
Zinc finger protein 688 (ZNF688) Krueppel C2H2-type zinc-finger protein family P0C7X2
Zinc finger protein 774 (ZNF774) Krueppel C2H2-type zinc-finger protein family Q6NX45
Zinc finger and BTB domain-containing protein 42 (ZBTB42) Krueppel C2H2-type zinc-finger protein family B2RXF5
Homeobox protein MSX-2 (MSX2) Msh homeobox family P35548
Homeobox protein MOX-1 (MEOX1) . P50221
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (HMG20B) . Q9P0W2
Other
Click To Hide/Show 46 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
14-3-3 protein sigma (SFN) 14-3-3 family P31947
Abl interactor 2 (ABI2) ABI family Q9NYB9
Apoptosis-stimulating of p53 protein 1 (PPP1R13B) ASPP family Q96KQ4
Bystin (BYSL) Bystin family Q13895
Centrosomal protein of 19 kDa (CEP19) CEP19 family Q96LK0
CWF19-like protein 2 (CWF19L2) CWF19 family Q2TBE0
Dedicator of cytokinesis protein 10 (DOCK10) DOCK family Q96BY6
Retrotransposon Gag-like protein 8A (RTL8A) FAM127 family Q9BWD3
Retrotransposon Gag-like protein 8B (RTL8B) FAM127 family Q17RB0
Retrotransposon Gag-like protein 8C (RTL8C) FAM127 family A6ZKI3
Protein FAM161A (FAM161A) FAM161 family Q3B820
Protein FAM217B (FAM217B) FAM217 family Q9NTX9
Radial spoke head 14 homolog (RSPH14) Flagellar radial spoke RSP14 family Q9UHP6
Keratin, type II cytoskeletal 75 (KRT75) Intermediate filament family O95678
Protein mago nashi homolog 2 (MAGOHB) Mago nashi family Q96A72
Microfibrillar-associated protein 1 (MFAP1) MFAP1 family P55081
Mitochondria-eating protein (SPATA18) MIEAP family Q8TC71
Phagosome assembly factor 1 (PHAF1) PHAF1 family Q9BSU1
Keratin-associated protein 13-3 (KRTAP13-3) PMG family Q3SY46
Paraneoplastic antigen-like protein 5 (PNMA5) PNMA family Q96PV4
Pro-opiomelanocortin (POMC) POMC family P01189
Pre-mRNA-splicing factor 18 (PRPF18) PRP18 family Q99633
SAGA-associated factor 29 (SGF29) SGF29 family Q96ES7
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (SMARCD1) SMARCD family Q96GM5
Spermatogenesis-associated protein 2 (SPATA2) SPATA2 family Q9UM82
Synaptonemal complex central element protein 1 (SYCE1) SYCE family Q8N0S2
Synaptotagmin-17 (SYT17) Synaptotagmin family Q9BSW7
T-complex protein 10A homolog 1 (TCP10L) TCP10 family Q8TDR4
Tuftelin-interacting protein 11 (TFIP11) TFP11/STIP family Q9UBB9
Troponin I, slow skeletal muscle (TNNI1) Troponin I family P19237
Vacuolar protein sorting-associated protein 52 homolog (VPS52) VPS52 family Q8N1B4
Ankyrin repeat domain-containing protein 23 (ANKRD23) . Q86SG2
Coiled-coil domain-containing protein 120 (CCDC120) . Q96HB5
EF-hand domain-containing family member C2 (EFHC2) . Q5JST6
Enkurin domain-containing protein 1 (ENKD1) . Q9H0I2
Fibronectin type III domain-containing protein 11 (FNDC11) . Q9BVV2
Leukocyte receptor cluster member 1 (LENG1) . Q96BZ8
LIM domain transcription factor LMO4 (LMO4) . P61968
NTF2-related export protein 2 (NXT2) . Q9NPJ8
Phostensin (PPP1R18) . Q6NYC8
PRKCA-binding protein (PICK1) . Q9NRD5
RAS protein activator like-3 (RASAL3) . Q86YV0
SRA stem-loop-interacting RNA-binding protein, mitochondrial (SLIRP) . Q9GZT3
Testis-specific protein 10-interacting protein (TSGA10IP) . Q3SY00
Uncharacterized protein C20orf202 (C20orf202) . A1L168
Vinexin (SORBS3) . O60504

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.