Details of the Target

General Information of Target

Target ID LDTP07321
Target Name Natural cytotoxicity triggering receptor 3 ligand 1 (NCR3LG1)
Gene Name NCR3LG1
Gene ID 374383
Synonyms
B7H6; Natural cytotoxicity triggering receptor 3 ligand 1; B7 homolog 6; B7-H6
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MTWRAAASTCAALLILLWALTTEGDLKVEMMAGGTQITPLNDNVTIFCNIFYSQPLNITS
MGITWFWKSLTFDKEVKVFEFFGDHQEAFRPGAIVSPWRLKSGDASLRLPGIQLEEAGEY
RCEVVVTPLKAQGTVQLEVVASPASRLLLDQVGMKENEDKYMCESSGFYPEAINITWEKQ
TQKFPHPIEISEDVITGPTIKNMDGTFNVTSCLKLNSSQEDPGTVYQCVVRHASLHTPLR
SNFTLTAARHSLSETEKTDNFSIHWWPISFIGVGLVLLIVLIPWKKICNKSSSAYTPLKC
ILKHWNSFDTQTLKKEHLIFFCTRAWPSYQLQDGEAWPPEGSVNINTIQQLDVFCRQEGK
WSEVPYVQAFFALRDNPDLCQCCRIDPALLTVTSGKSIDDNSTKSEKQTPREHSDAVPDA
PILPVSPIWEPPPATTSTTPVLSSQPPTLLLPLQ
Target Bioclass
Immunoglobulin
Subcellular location
Cell membrane
Function Triggers NCR3-dependent natural killer cell activation.
Uniprot ID
Q68D85
Ensemble ID
ENST00000338965.9
HGNC ID
HGNC:42400

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 6 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
OPA-S-S-alkyne
 Probe Info  		K101(2.58)  LDD3494  [1]
BTD
 Probe Info  		C300(0.30)  LDD2134  [2]
DBIA
 Probe Info  		C380(2.66); C383(3.41); C382(3.41)  LDD0080  [3]
IA-alkyne
 Probe Info  		C122(0.00); C322(0.00)  LDD0165  [4]
IPM
 Probe Info  		C382(0.00); C322(0.00)  LDD2156  [5]
AOyne
 Probe Info  		14.70  LDD0443  [6]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C380(0.90); C382(0.90); C383(0.86)  LDD0812  [3]
 LDCM0215  AC10 HEK-293T C380(1.16); C382(1.04); C383(1.04)  LDD0813  [3]
 LDCM0216  AC100 HEK-293T C380(1.02); C382(0.96); C383(1.25)  LDD0814  [3]
 LDCM0217  AC101 HEK-293T C380(0.97); C382(0.87); C383(1.09)  LDD0815  [3]
 LDCM0218  AC102 HEK-293T C380(1.06); C382(1.00); C383(1.28)  LDD0816  [3]
 LDCM0219  AC103 HEK-293T C380(0.97); C382(0.77); C383(1.42)  LDD0817  [3]
 LDCM0220  AC104 HEK-293T C380(1.16); C382(1.15); C383(1.37)  LDD0818  [3]
 LDCM0221  AC105 HEK-293T C380(0.99); C382(0.97); C383(1.13)  LDD0819  [3]
 LDCM0222  AC106 HEK-293T C380(0.91); C382(1.02); C383(0.88)  LDD0820  [3]
 LDCM0223  AC107 HEK-293T C380(1.12); C382(1.08); C383(1.20)  LDD0821  [3]
 LDCM0224  AC108 HEK-293T C380(0.94); C382(0.94); C383(1.08)  LDD0822  [3]
 LDCM0225  AC109 HEK-293T C380(1.02); C382(1.04); C383(1.10)  LDD0823  [3]
 LDCM0226  AC11 HEK-293T C380(1.23); C382(0.99); C383(0.99)  LDD0824  [3]
 LDCM0227  AC110 HEK-293T C380(1.20); C382(0.88); C383(1.65)  LDD0825  [3]
 LDCM0228  AC111 HEK-293T C380(1.41); C382(0.96); C383(2.21)  LDD0826  [3]
 LDCM0229  AC112 HEK-293T C380(1.33); C382(1.04); C383(1.83)  LDD0827  [3]
 LDCM0230  AC113 HEK-293T C380(0.98); C382(1.10); C383(1.09)  LDD0828  [3]
 LDCM0231  AC114 HEK-293T C380(1.00); C382(0.99); C383(1.03)  LDD0829  [3]
 LDCM0232  AC115 HEK-293T C380(1.03); C382(0.99); C383(0.91)  LDD0830  [3]
 LDCM0233  AC116 HEK-293T C380(1.20); C382(1.16); C383(1.40)  LDD0831  [3]
 LDCM0234  AC117 HEK-293T C380(1.12); C382(1.07); C383(1.29)  LDD0832  [3]
 LDCM0235  AC118 HEK-293T C380(0.97); C382(1.12); C383(0.85)  LDD0833  [3]
 LDCM0236  AC119 HEK-293T C380(1.06); C382(1.14); C383(0.87)  LDD0834  [3]
 LDCM0237  AC12 HEK-293T C380(1.63); C382(1.12); C383(1.12)  LDD0835  [3]
 LDCM0238  AC120 HEK-293T C380(1.14); C382(1.10); C383(0.91)  LDD0836  [3]
 LDCM0239  AC121 HEK-293T C380(1.21); C382(1.21); C383(1.14)  LDD0837  [3]
 LDCM0240  AC122 HEK-293T C380(1.30); C382(1.55); C383(1.15)  LDD0838  [3]
 LDCM0241  AC123 HEK-293T C380(1.22); C382(1.25); C383(0.91)  LDD0839  [3]
 LDCM0242  AC124 HEK-293T C380(1.00); C382(1.23); C383(0.86)  LDD0840  [3]
 LDCM0243  AC125 HEK-293T C380(1.28); C382(1.51); C383(1.13)  LDD0841  [3]
 LDCM0244  AC126 HEK-293T C380(1.50); C382(1.76); C383(1.33)  LDD0842  [3]
 LDCM0245  AC127 HEK-293T C380(1.44); C382(2.13); C383(1.08)  LDD0843  [3]
 LDCM0246  AC128 HEK-293T C380(1.09); C382(1.09); C383(1.02)  LDD0844  [3]
 LDCM0247  AC129 HEK-293T C380(1.14); C382(1.14); C383(1.16)  LDD0845  [3]
 LDCM0249  AC130 HEK-293T C380(0.91); C382(0.91); C383(1.03)  LDD0847  [3]
 LDCM0250  AC131 HEK-293T C380(1.06); C382(1.06); C383(0.90)  LDD0848  [3]
 LDCM0251  AC132 HEK-293T C380(1.18); C382(1.18); C383(1.11)  LDD0849  [3]
 LDCM0252  AC133 HEK-293T C380(1.00); C382(1.00); C383(1.50)  LDD0850  [3]
 LDCM0253  AC134 HEK-293T C380(1.17); C382(1.17); C383(1.23)  LDD0851  [3]
 LDCM0254  AC135 HEK-293T C380(1.00); C382(1.00); C383(1.29)  LDD0852  [3]
 LDCM0255  AC136 HEK-293T C380(1.09); C382(1.09); C383(1.19)  LDD0853  [3]
 LDCM0256  AC137 HEK-293T C380(1.26); C382(1.26); C383(1.61)  LDD0854  [3]
 LDCM0257  AC138 HEK-293T C380(1.11); C382(1.11); C383(1.62)  LDD0855  [3]
 LDCM0258  AC139 HEK-293T C380(1.16); C382(1.16); C383(1.46)  LDD0856  [3]
 LDCM0259  AC14 HEK-293T C380(1.23); C382(1.46); C383(1.46)  LDD0857  [3]
 LDCM0260  AC140 HEK-293T C380(1.11); C382(1.11); C383(1.22)  LDD0858  [3]
 LDCM0261  AC141 HEK-293T C380(1.09); C382(1.09); C383(1.41)  LDD0859  [3]
 LDCM0262  AC142 HEK-293T C380(1.20); C382(1.20); C383(1.29)  LDD0860  [3]
 LDCM0263  AC143 HEK-293T C380(0.94); C382(0.68); C383(1.10)  LDD0861  [3]
 LDCM0264  AC144 HEK-293T C380(1.17); C382(0.95); C383(1.53)  LDD0862  [3]
 LDCM0265  AC145 HEK-293T C380(1.17); C382(1.09); C383(1.63)  LDD0863  [3]
 LDCM0266  AC146 HEK-293T C380(1.10); C382(0.98); C383(1.51)  LDD0864  [3]
 LDCM0267  AC147 HEK-293T C380(1.12); C382(0.82); C383(1.65)  LDD0865  [3]
 LDCM0268  AC148 HEK-293T C380(0.97); C382(0.77); C383(1.37)  LDD0866  [3]
 LDCM0269  AC149 HEK-293T C380(0.97); C382(0.95); C383(0.98)  LDD0867  [3]
 LDCM0270  AC15 HEK-293T C380(1.69); C382(1.03); C383(1.03)  LDD0868  [3]
 LDCM0271  AC150 HEK-293T C380(0.96); C382(0.61); C383(1.21)  LDD0869  [3]
 LDCM0272  AC151 HEK-293T C380(1.12); C382(1.07); C383(1.34)  LDD0870  [3]
 LDCM0273  AC152 HEK-293T C380(1.04); C382(0.88); C383(1.21)  LDD0871  [3]
 LDCM0274  AC153 HEK-293T C380(1.00); C382(0.75); C383(1.29)  LDD0872  [3]
 LDCM0621  AC154 HEK-293T C380(0.98); C382(0.84); C383(1.07)  LDD2162  [3]
 LDCM0622  AC155 HEK-293T C380(0.97); C382(0.82); C383(1.12)  LDD2163  [3]
 LDCM0623  AC156 HEK-293T C380(1.18); C382(0.93); C383(1.66)  LDD2164  [3]
 LDCM0624  AC157 HEK-293T C380(1.13); C382(0.80); C383(2.04)  LDD2165  [3]
 LDCM0276  AC17 HEK-293T C380(1.08); C382(1.20); C383(1.88)  LDD0874  [3]
 LDCM0277  AC18 HEK-293T C380(1.18); C382(1.13); C383(1.29)  LDD0875  [3]
 LDCM0278  AC19 HEK-293T C380(1.00); C382(1.05); C383(1.19)  LDD0876  [3]
 LDCM0279  AC2 HEK-293T C380(1.05); C382(1.05); C383(0.94)  LDD0877  [3]
 LDCM0280  AC20 HEK-293T C380(0.96); C382(1.02); C383(2.02)  LDD0878  [3]
 LDCM0281  AC21 HEK-293T C380(1.16); C382(1.08); C383(1.62)  LDD0879  [3]
 LDCM0282  AC22 HEK-293T C380(1.00); C382(0.99); C383(1.69)  LDD0880  [3]
 LDCM0283  AC23 HEK-293T C380(1.39); C382(1.23); C383(2.21)  LDD0881  [3]
 LDCM0284  AC24 HEK-293T C380(0.88); C382(1.03); C383(1.25)  LDD0882  [3]
 LDCM0285  AC25 HEK-293T C380(1.02); C382(0.89); C383(0.96)  LDD0883  [3]
 LDCM0286  AC26 HEK-293T C380(1.16); C382(1.11); C383(1.02)  LDD0884  [3]
 LDCM0287  AC27 HEK-293T C380(1.02); C382(1.06); C383(1.06)  LDD0885  [3]
 LDCM0288  AC28 HEK-293T C380(0.88); C382(0.89); C383(1.02)  LDD0886  [3]
 LDCM0289  AC29 HEK-293T C380(1.03); C382(1.09); C383(0.98)  LDD0887  [3]
 LDCM0290  AC3 HEK-293T C380(0.90); C382(0.90); C383(0.88)  LDD0888  [3]
 LDCM0291  AC30 HEK-293T C380(1.06); C382(1.19); C383(1.08)  LDD0889  [3]
 LDCM0292  AC31 HEK-293T C380(0.92); C382(0.91); C383(0.77)  LDD0890  [3]
 LDCM0293  AC32 HEK-293T C380(0.98); C382(0.97); C383(0.94)  LDD0891  [3]
 LDCM0294  AC33 HEK-293T C380(0.96); C382(1.03); C383(0.93)  LDD0892  [3]
 LDCM0295  AC34 HEK-293T C380(1.08); C382(0.97); C383(0.93)  LDD0893  [3]
 LDCM0296  AC35 HEK-293T C380(0.95); C382(0.95)  LDD0894  [3]
 LDCM0297  AC36 HEK-293T C380(1.14); C382(1.14)  LDD0895  [3]
 LDCM0298  AC37 HEK-293T C380(1.00); C382(1.00)  LDD0896  [3]
 LDCM0299  AC38 HEK-293T C380(1.15); C382(1.15)  LDD0897  [3]
 LDCM0300  AC39 HEK-293T C380(1.19); C382(1.19)  LDD0898  [3]
 LDCM0301  AC4 HEK-293T C380(0.95); C382(0.95); C383(0.96)  LDD0899  [3]
 LDCM0302  AC40 HEK-293T C380(1.00); C382(1.00)  LDD0900  [3]
 LDCM0303  AC41 HEK-293T C380(1.12); C382(1.12)  LDD0901  [3]
 LDCM0304  AC42 HEK-293T C380(0.98); C382(0.98)  LDD0902  [3]
 LDCM0305  AC43 HEK-293T C380(1.23); C382(1.23)  LDD0903  [3]
 LDCM0306  AC44 HEK-293T C380(1.12); C382(1.12)  LDD0904  [3]
 LDCM0307  AC45 HEK-293T C380(1.28); C382(1.28)  LDD0905  [3]
 LDCM0308  AC46 HEK-293T C380(1.03); C382(1.03); C383(0.99)  LDD0906  [3]
 LDCM0309  AC47 HEK-293T C380(1.10); C382(1.10); C383(1.07)  LDD0907  [3]
 LDCM0310  AC48 HEK-293T C380(1.00); C382(1.00); C383(1.11)  LDD0908  [3]
 LDCM0311  AC49 HEK-293T C380(1.08); C382(1.08); C383(1.09)  LDD0909  [3]
 LDCM0312  AC5 HEK-293T C380(0.87); C382(0.87); C383(0.85)  LDD0910  [3]
 LDCM0313  AC50 HEK-293T C380(1.13); C382(1.13); C383(1.27)  LDD0911  [3]
 LDCM0314  AC51 HEK-293T C380(1.22); C382(1.22); C383(1.31)  LDD0912  [3]
 LDCM0315  AC52 HEK-293T C380(1.05); C382(1.05); C383(1.39)  LDD0913  [3]
 LDCM0316  AC53 HEK-293T C380(1.14); C382(1.14); C383(1.12)  LDD0914  [3]
 LDCM0317  AC54 HEK-293T C380(1.19); C382(1.19); C383(1.29)  LDD0915  [3]
 LDCM0318  AC55 HEK-293T C380(1.23); C382(1.23); C383(1.21)  LDD0916  [3]
 LDCM0319  AC56 HEK-293T C380(1.06); C382(1.06); C383(1.14)  LDD0917  [3]
 LDCM0320  AC57 HEK-293T C383(1.12)  LDD0918  [3]
 LDCM0321  AC58 HEK-293T C383(0.95)  LDD0919  [3]
 LDCM0322  AC59 HEK-293T C383(0.99)  LDD0920  [3]
 LDCM0323  AC6 HEK-293T C380(1.29); C382(1.10); C383(1.10)  LDD0921  [3]
 LDCM0324  AC60 HEK-293T C383(0.77)  LDD0922  [3]
 LDCM0325  AC61 HEK-293T C383(1.16)  LDD0923  [3]
 LDCM0326  AC62 HEK-293T C383(1.00)  LDD0924  [3]
 LDCM0327  AC63 HEK-293T C383(1.04)  LDD0925  [3]
 LDCM0328  AC64 HEK-293T C383(0.92)  LDD0926  [3]
 LDCM0329  AC65 HEK-293T C383(1.07)  LDD0927  [3]
 LDCM0330  AC66 HEK-293T C383(1.00)  LDD0928  [3]
 LDCM0331  AC67 HEK-293T C383(1.08)  LDD0929  [3]
 LDCM0332  AC68 HEK-293T C380(1.00); C382(1.07); C383(1.11)  LDD0930  [3]
 LDCM0333  AC69 HEK-293T C380(1.03); C382(1.16); C383(1.16)  LDD0931  [3]
 LDCM0334  AC7 HEK-293T C380(1.43); C382(1.13); C383(1.13)  LDD0932  [3]
 LDCM0335  AC70 HEK-293T C380(1.37); C382(1.18); C383(1.14)  LDD0933  [3]
 LDCM0336  AC71 HEK-293T C380(1.17); C382(1.07); C383(1.05)  LDD0934  [3]
 LDCM0337  AC72 HEK-293T C380(0.99); C382(1.14); C383(1.16)  LDD0935  [3]
 LDCM0338  AC73 HEK-293T C380(1.14); C382(1.16); C383(0.97)  LDD0936  [3]
 LDCM0339  AC74 HEK-293T C380(1.15); C382(1.42); C383(1.26)  LDD0937  [3]
 LDCM0340  AC75 HEK-293T C380(0.81); C382(1.08); C383(1.04)  LDD0938  [3]
 LDCM0341  AC76 HEK-293T C380(1.05); C382(1.15); C383(1.10)  LDD0939  [3]
 LDCM0342  AC77 HEK-293T C380(1.00); C382(1.00); C383(1.10)  LDD0940  [3]
 LDCM0343  AC78 HEK-293T C380(0.94); C382(1.18); C383(1.13)  LDD0941  [3]
 LDCM0344  AC79 HEK-293T C380(0.97); C382(1.14); C383(1.15)  LDD0942  [3]
 LDCM0345  AC8 HEK-293T C380(1.55); C382(1.16); C383(1.16)  LDD0943  [3]
 LDCM0346  AC80 HEK-293T C380(0.98); C382(1.10); C383(1.13)  LDD0944  [3]
 LDCM0347  AC81 HEK-293T C380(0.99); C382(1.05); C383(1.20)  LDD0945  [3]
 LDCM0348  AC82 HEK-293T C380(1.15); C382(1.34); C383(1.46)  LDD0946  [3]
 LDCM0349  AC83 HEK-293T C380(1.03); C382(0.97); C383(1.02)  LDD0947  [3]
 LDCM0350  AC84 HEK-293T C380(1.13); C382(1.03); C383(1.18)  LDD0948  [3]
 LDCM0351  AC85 HEK-293T C380(1.05); C382(0.91); C383(1.07)  LDD0949  [3]
 LDCM0352  AC86 HEK-293T C380(1.09); C382(1.04); C383(1.00)  LDD0950  [3]
 LDCM0353  AC87 HEK-293T C380(1.10); C382(1.08); C383(1.19)  LDD0951  [3]
 LDCM0354  AC88 HEK-293T C380(1.13); C382(0.98); C383(1.15)  LDD0952  [3]
 LDCM0355  AC89 HEK-293T C380(1.24); C382(1.11); C383(1.23)  LDD0953  [3]
 LDCM0357  AC90 HEK-293T C380(1.07); C382(1.00); C383(1.22)  LDD0955  [3]
 LDCM0358  AC91 HEK-293T C380(1.15); C382(0.98); C383(1.15)  LDD0956  [3]
 LDCM0359  AC92 HEK-293T C380(1.12); C382(0.91); C383(1.00)  LDD0957  [3]
 LDCM0360  AC93 HEK-293T C380(1.11); C382(1.00); C383(1.18)  LDD0958  [3]
 LDCM0361  AC94 HEK-293T C380(1.16); C382(1.03); C383(1.27)  LDD0959  [3]
 LDCM0362  AC95 HEK-293T C380(1.17); C382(0.97); C383(1.16)  LDD0960  [3]
 LDCM0363  AC96 HEK-293T C380(1.15); C382(1.02); C383(1.16)  LDD0961  [3]
 LDCM0364  AC97 HEK-293T C380(1.59); C382(0.97); C383(1.98)  LDD0962  [3]
 LDCM0365  AC98 HEK-293T C380(0.95); C382(0.91); C383(1.18)  LDD0963  [3]
 LDCM0366  AC99 HEK-293T C380(0.91); C382(0.87); C383(1.08)  LDD0964  [3]
 LDCM0248  AKOS034007472 HEK-293T C380(1.22); C382(1.27); C383(1.27)  LDD0846  [3]
 LDCM0356  AKOS034007680 HEK-293T C380(1.88); C382(1.25); C383(1.25)  LDD0954  [3]
 LDCM0275  AKOS034007705 HEK-293T C380(1.48); C382(1.71); C383(1.71)  LDD0873  [3]
 LDCM0367  CL1 HEK-293T C380(1.30); C382(1.51)  LDD0965  [3]
 LDCM0368  CL10 HEK-293T C380(2.43); C382(2.61)  LDD0966  [3]
 LDCM0369  CL100 HEK-293T C380(1.25); C382(1.25); C383(1.14)  LDD0967  [3]
 LDCM0370  CL101 HEK-293T C380(1.31); C382(0.99); C383(0.99)  LDD0968  [3]
 LDCM0371  CL102 HEK-293T C380(2.34); C382(1.01); C383(1.01)  LDD0969  [3]
 LDCM0372  CL103 HEK-293T C380(1.62); C382(1.23); C383(1.23)  LDD0970  [3]
 LDCM0373  CL104 HEK-293T C380(1.31); C382(1.14); C383(1.14)  LDD0971  [3]
 LDCM0374  CL105 HEK-293T C380(1.43); C382(1.20); C383(1.15)  LDD0972  [3]
 LDCM0375  CL106 HEK-293T C380(1.78); C382(1.32); C383(1.34)  LDD0973  [3]
 LDCM0376  CL107 HEK-293T C380(1.12); C382(0.98); C383(1.63)  LDD0974  [3]
 LDCM0377  CL108 HEK-293T C380(1.18); C382(1.12); C383(1.16)  LDD0975  [3]
 LDCM0378  CL109 HEK-293T C380(3.19); C382(2.14); C383(1.27)  LDD0976  [3]
 LDCM0379  CL11 HEK-293T C380(1.56); C382(1.93)  LDD0977  [3]
 LDCM0380  CL110 HEK-293T C380(1.69); C382(1.48); C383(1.39)  LDD0978  [3]
 LDCM0381  CL111 HEK-293T C380(1.87); C382(1.39); C383(1.39)  LDD0979  [3]
 LDCM0382  CL112 HEK-293T C380(1.28); C382(1.33); C383(1.19)  LDD0980  [3]
 LDCM0383  CL113 HEK-293T C380(1.02); C382(0.91); C383(1.02)  LDD0981  [3]
 LDCM0384  CL114 HEK-293T C380(1.82); C382(1.51); C383(1.38)  LDD0982  [3]
 LDCM0385  CL115 HEK-293T C380(1.09); C382(1.25); C383(1.03)  LDD0983  [3]
 LDCM0386  CL116 HEK-293T C380(1.11); C382(1.15); C383(1.02)  LDD0984  [3]
 LDCM0387  CL117 HEK-293T C380(1.18); C382(1.18)  LDD0985  [3]
 LDCM0388  CL118 HEK-293T C380(1.04); C382(1.04)  LDD0986  [3]
 LDCM0389  CL119 HEK-293T C380(1.05); C382(1.05)  LDD0987  [3]
 LDCM0390  CL12 HEK-293T C380(1.17); C382(1.29)  LDD0988  [3]
 LDCM0391  CL120 HEK-293T C380(1.10); C382(1.10)  LDD0989  [3]
 LDCM0392  CL121 HEK-293T C380(1.72); C382(1.72); C383(1.42)  LDD0990  [3]
 LDCM0393  CL122 HEK-293T C380(1.46); C382(1.46); C383(1.15)  LDD0991  [3]
 LDCM0394  CL123 HEK-293T C380(1.57); C382(1.57); C383(1.00)  LDD0992  [3]
 LDCM0395  CL124 HEK-293T C380(1.56); C382(1.56); C383(1.10)  LDD0993  [3]
 LDCM0396  CL125 HEK-293T C383(1.13)  LDD0994  [3]
 LDCM0397  CL126 HEK-293T C383(0.93)  LDD0995  [3]
 LDCM0398  CL127 HEK-293T C383(0.86)  LDD0996  [3]
 LDCM0399  CL128 HEK-293T C383(1.04)  LDD0997  [3]
 LDCM0400  CL13 HEK-293T C380(1.12); C382(1.11)  LDD0998  [3]
 LDCM0401  CL14 HEK-293T C380(1.62); C382(1.54)  LDD0999  [3]
 LDCM0402  CL15 HEK-293T C380(2.25); C382(2.35)  LDD1000  [3]
 LDCM0403  CL16 HEK-293T C380(0.99); C382(0.82); C383(1.70)  LDD1001  [3]
 LDCM0404  CL17 HEK-293T C380(1.51); C382(1.09); C383(0.94)  LDD1002  [3]
 LDCM0405  CL18 HEK-293T C380(1.02); C382(1.11); C383(1.61)  LDD1003  [3]
 LDCM0406  CL19 HEK-293T C380(1.07); C382(0.97); C383(0.77)  LDD1004  [3]
 LDCM0407  CL2 HEK-293T C380(1.26); C382(1.43)  LDD1005  [3]
 LDCM0408  CL20 HEK-293T C380(1.24); C382(1.12); C383(1.31)  LDD1006  [3]
 LDCM0409  CL21 HEK-293T C380(1.99); C382(1.42); C383(1.11)  LDD1007  [3]
 LDCM0410  CL22 HEK-293T C380(1.01); C382(1.13); C383(1.37)  LDD1008  [3]
 LDCM0411  CL23 HEK-293T C380(0.87); C382(1.00); C383(0.58)  LDD1009  [3]
 LDCM0412  CL24 HEK-293T C380(0.95); C382(0.97); C383(0.85)  LDD1010  [3]
 LDCM0413  CL25 HEK-293T C380(1.43); C382(0.91); C383(1.31)  LDD1011  [3]
 LDCM0414  CL26 HEK-293T C380(0.96); C382(0.95); C383(1.11)  LDD1012  [3]
 LDCM0415  CL27 HEK-293T C380(1.04); C382(1.03); C383(0.95)  LDD1013  [3]
 LDCM0416  CL28 HEK-293T C380(1.19); C382(0.91); C383(0.82)  LDD1014  [3]
 LDCM0417  CL29 HEK-293T C380(1.06); C382(0.99); C383(0.79)  LDD1015  [3]
 LDCM0418  CL3 HEK-293T C380(1.24); C382(1.25)  LDD1016  [3]
 LDCM0419  CL30 HEK-293T C380(1.50); C382(1.39); C383(1.42)  LDD1017  [3]
 LDCM0420  CL31 HEK-293T C382(0.96); C383(1.53)  LDD1018  [3]
 LDCM0421  CL32 HEK-293T C382(1.10); C383(1.15)  LDD1019  [3]
 LDCM0422  CL33 HEK-293T C382(1.49); C383(1.20)  LDD1020  [3]
 LDCM0423  CL34 HEK-293T C382(1.84); C383(1.17)  LDD1021  [3]
 LDCM0424  CL35 HEK-293T C382(1.08); C383(1.30)  LDD1022  [3]
 LDCM0425  CL36 HEK-293T C382(0.91); C383(1.09)  LDD1023  [3]
 LDCM0426  CL37 HEK-293T C382(1.03); C383(1.25)  LDD1024  [3]
 LDCM0428  CL39 HEK-293T C382(1.45); C383(2.88)  LDD1026  [3]
 LDCM0429  CL4 HEK-293T C380(1.76); C382(1.58)  LDD1027  [3]
 LDCM0430  CL40 HEK-293T C382(1.26); C383(1.32)  LDD1028  [3]
 LDCM0431  CL41 HEK-293T C382(1.65); C383(1.69)  LDD1029  [3]
 LDCM0432  CL42 HEK-293T C382(1.54); C383(2.38)  LDD1030  [3]
 LDCM0433  CL43 HEK-293T C382(1.16); C383(2.25)  LDD1031  [3]
 LDCM0434  CL44 HEK-293T C382(1.28); C383(1.27)  LDD1032  [3]
 LDCM0435  CL45 HEK-293T C382(1.46); C383(2.15)  LDD1033  [3]
 LDCM0436  CL46 HEK-293T C383(1.91)  LDD1034  [3]
 LDCM0437  CL47 HEK-293T C383(1.28)  LDD1035  [3]
 LDCM0438  CL48 HEK-293T C383(1.17)  LDD1036  [3]
 LDCM0439  CL49 HEK-293T C383(1.28)  LDD1037  [3]
 LDCM0440  CL5 HEK-293T C380(1.22); C382(1.29)  LDD1038  [3]
 LDCM0441  CL50 HEK-293T C383(1.32)  LDD1039  [3]
 LDCM0442  CL51 HEK-293T C383(1.03)  LDD1040  [3]
 LDCM0443  CL52 HEK-293T C383(0.81)  LDD1041  [3]
 LDCM0444  CL53 HEK-293T C383(0.57)  LDD1042  [3]
 LDCM0445  CL54 HEK-293T C383(0.74)  LDD1043  [3]
 LDCM0446  CL55 HEK-293T C383(1.14)  LDD1044  [3]
 LDCM0447  CL56 HEK-293T C383(0.72)  LDD1045  [3]
 LDCM0448  CL57 HEK-293T C383(0.87)  LDD1046  [3]
 LDCM0449  CL58 HEK-293T C383(0.66)  LDD1047  [3]
 LDCM0450  CL59 HEK-293T C383(1.11)  LDD1048  [3]
 LDCM0451  CL6 HEK-293T C380(1.68); C382(1.83)  LDD1049  [3]
 LDCM0452  CL60 HEK-293T C383(1.39)  LDD1050  [3]
 LDCM0453  CL61 HEK-293T C380(0.89); C383(1.80)  LDD1051  [3]
 LDCM0454  CL62 HEK-293T C380(1.08); C383(1.13)  LDD1052  [3]
 LDCM0455  CL63 HEK-293T C380(1.18); C383(1.24)  LDD1053  [3]
 LDCM0456  CL64 HEK-293T C380(1.66); C383(0.98)  LDD1054  [3]
 LDCM0457  CL65 HEK-293T C380(1.14); C383(1.01)  LDD1055  [3]
 LDCM0458  CL66 HEK-293T C380(1.23); C383(1.02)  LDD1056  [3]
 LDCM0459  CL67 HEK-293T C380(1.18); C383(0.83)  LDD1057  [3]
 LDCM0460  CL68 HEK-293T C380(1.14); C383(1.05)  LDD1058  [3]
 LDCM0461  CL69 HEK-293T C380(1.07); C383(0.93)  LDD1059  [3]
 LDCM0462  CL7 HEK-293T C380(1.22); C382(1.56)  LDD1060  [3]
 LDCM0463  CL70 HEK-293T C380(1.09); C383(0.96)  LDD1061  [3]
 LDCM0464  CL71 HEK-293T C380(1.07); C383(1.06)  LDD1062  [3]
 LDCM0465  CL72 HEK-293T C380(0.89); C383(1.29)  LDD1063  [3]
 LDCM0466  CL73 HEK-293T C380(1.29); C383(1.21)  LDD1064  [3]
 LDCM0467  CL74 HEK-293T C380(1.65); C383(2.11)  LDD1065  [3]
 LDCM0469  CL76 HEK-293T C383(0.93)  LDD1067  [3]
 LDCM0470  CL77 HEK-293T C383(1.00)  LDD1068  [3]
 LDCM0471  CL78 HEK-293T C383(0.64)  LDD1069  [3]
 LDCM0472  CL79 HEK-293T C383(0.99)  LDD1070  [3]
 LDCM0473  CL8 HEK-293T C382(1.38)  LDD1071  [3]
 LDCM0474  CL80 HEK-293T C383(0.88)  LDD1072  [3]
 LDCM0475  CL81 HEK-293T C383(0.92)  LDD1073  [3]
 LDCM0476  CL82 HEK-293T C383(1.32)  LDD1074  [3]
 LDCM0477  CL83 HEK-293T C383(1.13)  LDD1075  [3]
 LDCM0478  CL84 HEK-293T C383(0.86)  LDD1076  [3]
 LDCM0479  CL85 HEK-293T C383(0.89)  LDD1077  [3]
 LDCM0480  CL86 HEK-293T C383(0.83)  LDD1078  [3]
 LDCM0481  CL87 HEK-293T C383(0.90)  LDD1079  [3]
 LDCM0482  CL88 HEK-293T C383(1.04)  LDD1080  [3]
 LDCM0483  CL89 HEK-293T C383(0.83)  LDD1081  [3]
 LDCM0484  CL9 HEK-293T C382(1.18)  LDD1082  [3]
 LDCM0485  CL90 HEK-293T C383(1.05)  LDD1083  [3]
 LDCM0486  CL91 HEK-293T C380(1.20); C382(1.20); C383(1.06)  LDD1084  [3]
 LDCM0487  CL92 HEK-293T C380(1.58); C382(1.58); C383(1.66)  LDD1085  [3]
 LDCM0488  CL93 HEK-293T C380(1.33); C382(1.33); C383(1.36)  LDD1086  [3]
 LDCM0489  CL94 HEK-293T C380(1.36); C382(1.36); C383(1.30)  LDD1087  [3]
 LDCM0490  CL95 HEK-293T C380(1.94); C382(1.94); C383(1.59)  LDD1088  [3]
 LDCM0491  CL96 HEK-293T C380(1.35); C382(1.35); C383(1.28)  LDD1089  [3]
 LDCM0492  CL97 HEK-293T C380(1.83); C382(1.83); C383(1.49)  LDD1090  [3]
 LDCM0493  CL98 HEK-293T C380(1.53); C382(1.53); C383(1.49)  LDD1091  [3]
 LDCM0494  CL99 HEK-293T C380(1.42); C382(1.42); C383(1.40)  LDD1092  [3]
 LDCM0495  E2913 HEK-293T C322(0.57); C122(1.09); C163(1.03); C382(1.07)  LDD1698  [7]
 LDCM0468  Fragment33 HEK-293T C380(1.47); C383(1.60)  LDD1066  [3]
 LDCM0427  Fragment51 HEK-293T C382(1.49); C383(1.21)  LDD1025  [3]
 LDCM0022  KB02 HCT 116 C380(2.66); C383(3.41); C382(3.41)  LDD0080  [3]
 LDCM0023  KB03 HCT 116 C380(2.83); C383(2.56); C382(2.56)  LDD0081  [3]
 LDCM0024  KB05 HCT 116 C380(3.82); C383(3.24); C382(3.24)  LDD0082  [3]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C300(0.30)  LDD2134  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 (PLPP6) PA-phosphatase related phosphoesterase family Q8IY26
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Transmembrane protein 14C (TMEM14C) TMEM14 family Q9P0S9
Translocator protein (TSPO) TspO/BZRP family P30536
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Natural cytotoxicity triggering receptor 3 (NCR3) Natural cytotoxicity receptor (NCR) family O14931
Other
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ergosterol biosynthetic protein 28 homolog (ERG28) ERG28 family Q9UKR5
Syntaxin-8 (STX8) Syntaxin family Q9UNK0
Nutritionally-regulated adipose and cardiac enriched protein homolog (NRAC) . Q8N912
TPA-induced transmembrane protein (TTMP) . Q5BVD1
Transmembrane protein 222 (TMEM222) . Q9H0R3

References

1 A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell. Nat Commun. 2024 Apr 8;15(1):2997. doi: 10.1038/s41467-024-47033-w.
Mass spectrometry data entry: PXD042888
2 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
5 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
6 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
7 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402