Details of the Target

General Information of Target

Target ID LDTP07055
Target Name RNA-binding protein 48 (RBM48)
Gene Name RBM48
Gene ID 84060
Synonyms
C7orf64; RNA-binding protein 48
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MASSGGELGSLFDHHVQRAVCDTRAKYREGRRPRAVKVYTINLESQYLLIQGVPAVGVMK
ELVERFALYGAIEQYNALDEYPAEDFTEVYLIKFMNLQSARTAKRKMDEQSFFGGLLHVC
YAPEFETVEETRKKLQMRKAYVVKTTENKDHYVTKKKLVTEHKDTEDFRQDFHSEMSGFC
KAALNTSAGNSNPYLPYSCELPLCYFSSKCMCSSGGPVDRAPDSSKDGRNHHKTMGHYNH
NDSLRKTQINSLKNSVACPGAQKAITSSEAVDRFMPRTTQLQERKRRREDDRKLGTFLQT
NPTGNEIMIGPLLPDISKVDMHDDSLNTTANLIRHKLKEVISSVPKPPEDKPEDVHTSHP
LKQRRRI
Target Bioclass
Other
Family
RBM48 family
Function As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
Uniprot ID
Q5RL73
Ensemble ID
ENST00000265732.10
HGNC ID
HGNC:21785

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CMK SNV: p.I307N .
U87MG SNV: p.H356Y .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C258(20.00)  LDD1704  [1]
DBIA
 Probe Info  		C258(2.83)  LDD0080  [2]
IPM
 Probe Info  		N.A.  LDD0147  [3]
TFBX
 Probe Info  		N.A.  LDD0148  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C210(1.03)  LDD0812  [2]
 LDCM0215  AC10 HEK-293T C210(1.17)  LDD0813  [2]
 LDCM0216  AC100 HEK-293T C210(1.90)  LDD0814  [2]
 LDCM0217  AC101 HEK-293T C210(1.96)  LDD0815  [2]
 LDCM0218  AC102 HEK-293T C210(1.98)  LDD0816  [2]
 LDCM0219  AC103 HEK-293T C210(2.19)  LDD0817  [2]
 LDCM0220  AC104 HEK-293T C210(1.31)  LDD0818  [2]
 LDCM0221  AC105 HEK-293T C210(1.63)  LDD0819  [2]
 LDCM0222  AC106 HEK-293T C210(1.06)  LDD0820  [2]
 LDCM0223  AC107 HEK-293T C210(1.36)  LDD0821  [2]
 LDCM0224  AC108 HEK-293T C210(1.14)  LDD0822  [2]
 LDCM0225  AC109 HEK-293T C210(1.58)  LDD0823  [2]
 LDCM0226  AC11 HEK-293T C210(1.12)  LDD0824  [2]
 LDCM0227  AC110 HEK-293T C210(1.77)  LDD0825  [2]
 LDCM0228  AC111 HEK-293T C210(1.70)  LDD0826  [2]
 LDCM0229  AC112 HEK-293T C210(2.30)  LDD0827  [2]
 LDCM0230  AC113 HEK-293T C210(0.91)  LDD0828  [2]
 LDCM0231  AC114 HEK-293T C210(0.75)  LDD0829  [2]
 LDCM0232  AC115 HEK-293T C210(0.86)  LDD0830  [2]
 LDCM0233  AC116 HEK-293T C210(1.10)  LDD0831  [2]
 LDCM0234  AC117 HEK-293T C210(1.13)  LDD0832  [2]
 LDCM0235  AC118 HEK-293T C210(1.17)  LDD0833  [2]
 LDCM0236  AC119 HEK-293T C210(1.27)  LDD0834  [2]
 LDCM0237  AC12 HEK-293T C210(1.07)  LDD0835  [2]
 LDCM0238  AC120 HEK-293T C210(0.74)  LDD0836  [2]
 LDCM0239  AC121 HEK-293T C210(1.01)  LDD0837  [2]
 LDCM0240  AC122 HEK-293T C210(1.01)  LDD0838  [2]
 LDCM0241  AC123 HEK-293T C210(0.93)  LDD0839  [2]
 LDCM0242  AC124 HEK-293T C210(0.95)  LDD0840  [2]
 LDCM0243  AC125 HEK-293T C210(1.31)  LDD0841  [2]
 LDCM0244  AC126 HEK-293T C210(0.97)  LDD0842  [2]
 LDCM0245  AC127 HEK-293T C210(1.13)  LDD0843  [2]
 LDCM0246  AC128 HEK-293T C210(0.79)  LDD0844  [2]
 LDCM0247  AC129 HEK-293T C210(0.82)  LDD0845  [2]
 LDCM0249  AC130 HEK-293T C210(1.04)  LDD0847  [2]
 LDCM0250  AC131 HEK-293T C210(0.80)  LDD0848  [2]
 LDCM0251  AC132 HEK-293T C210(1.14)  LDD0849  [2]
 LDCM0252  AC133 HEK-293T C210(1.19)  LDD0850  [2]
 LDCM0253  AC134 HEK-293T C210(1.26)  LDD0851  [2]
 LDCM0254  AC135 HEK-293T C210(1.05)  LDD0852  [2]
 LDCM0255  AC136 HEK-293T C210(1.01)  LDD0853  [2]
 LDCM0256  AC137 HEK-293T C210(1.14)  LDD0854  [2]
 LDCM0257  AC138 HEK-293T C210(1.06)  LDD0855  [2]
 LDCM0258  AC139 HEK-293T C210(0.88)  LDD0856  [2]
 LDCM0259  AC14 HEK-293T C210(1.32)  LDD0857  [2]
 LDCM0260  AC140 HEK-293T C210(1.30)  LDD0858  [2]
 LDCM0261  AC141 HEK-293T C210(1.40)  LDD0859  [2]
 LDCM0262  AC142 HEK-293T C210(1.13)  LDD0860  [2]
 LDCM0263  AC143 HEK-293T C210(0.80)  LDD0861  [2]
 LDCM0264  AC144 HEK-293T C210(1.05)  LDD0862  [2]
 LDCM0265  AC145 HEK-293T C210(1.09)  LDD0863  [2]
 LDCM0266  AC146 HEK-293T C210(1.43)  LDD0864  [2]
 LDCM0267  AC147 HEK-293T C210(1.53)  LDD0865  [2]
 LDCM0268  AC148 HEK-293T C210(1.34)  LDD0866  [2]
 LDCM0269  AC149 HEK-293T C210(1.03)  LDD0867  [2]
 LDCM0270  AC15 HEK-293T C210(1.23)  LDD0868  [2]
 LDCM0271  AC150 HEK-293T C210(1.19)  LDD0869  [2]
 LDCM0272  AC151 HEK-293T C210(1.32)  LDD0870  [2]
 LDCM0273  AC152 HEK-293T C210(1.67)  LDD0871  [2]
 LDCM0274  AC153 HEK-293T C210(1.13)  LDD0872  [2]
 LDCM0621  AC154 HEK-293T C210(0.94)  LDD2162  [2]
 LDCM0622  AC155 HEK-293T C210(1.08)  LDD2163  [2]
 LDCM0623  AC156 HEK-293T C210(1.45)  LDD2164  [2]
 LDCM0624  AC157 HEK-293T C210(1.25)  LDD2165  [2]
 LDCM0276  AC17 HEK-293T C210(1.17)  LDD0874  [2]
 LDCM0277  AC18 HEK-293T C210(0.87)  LDD0875  [2]
 LDCM0278  AC19 HEK-293T C210(0.98)  LDD0876  [2]
 LDCM0279  AC2 HEK-293T C210(1.31)  LDD0877  [2]
 LDCM0280  AC20 HEK-293T C210(0.92)  LDD0878  [2]
 LDCM0281  AC21 HEK-293T C210(1.30)  LDD0879  [2]
 LDCM0282  AC22 HEK-293T C210(0.96)  LDD0880  [2]
 LDCM0283  AC23 HEK-293T C210(1.27)  LDD0881  [2]
 LDCM0284  AC24 HEK-293T C210(1.04)  LDD0882  [2]
 LDCM0285  AC25 HEK-293T C210(0.99)  LDD0883  [2]
 LDCM0286  AC26 HEK-293T C210(0.79)  LDD0884  [2]
 LDCM0287  AC27 HEK-293T C210(0.95)  LDD0885  [2]
 LDCM0288  AC28 HEK-293T C210(1.90)  LDD0886  [2]
 LDCM0289  AC29 HEK-293T C210(0.77)  LDD0887  [2]
 LDCM0290  AC3 HEK-293T C210(1.05)  LDD0888  [2]
 LDCM0291  AC30 HEK-293T C210(0.72)  LDD0889  [2]
 LDCM0292  AC31 HEK-293T C210(0.70)  LDD0890  [2]
 LDCM0293  AC32 HEK-293T C210(0.70)  LDD0891  [2]
 LDCM0294  AC33 HEK-293T C210(0.69)  LDD0892  [2]
 LDCM0295  AC34 HEK-293T C210(0.61)  LDD0893  [2]
 LDCM0296  AC35 HEK-293T C258(0.96); C210(0.91)  LDD1535  [4]
 LDCM0298  AC37 HEK-293T C212(0.87)  LDD1537  [4]
 LDCM0300  AC39 HEK-293T C210(0.96)  LDD1539  [4]
 LDCM0301  AC4 HEK-293T C210(1.14)  LDD0899  [2]
 LDCM0302  AC40 HEK-293T C258(1.02); C210(0.98)  LDD1541  [4]
 LDCM0303  AC41 HEK-293T C180(1.10); C212(0.98)  LDD1542  [4]
 LDCM0304  AC42 HEK-293T C210(1.05)  LDD1543  [4]
 LDCM0305  AC43 HEK-293T C258(0.98); C210(1.00)  LDD1544  [4]
 LDCM0307  AC45 HEK-293T C212(0.81)  LDD1546  [4]
 LDCM0308  AC46 HEK-293T C210(1.43)  LDD0906  [2]
 LDCM0309  AC47 HEK-293T C210(1.59)  LDD0907  [2]
 LDCM0310  AC48 HEK-293T C210(1.31)  LDD0908  [2]
 LDCM0311  AC49 HEK-293T C210(1.22)  LDD0909  [2]
 LDCM0312  AC5 HEK-293T C210(1.20)  LDD0910  [2]
 LDCM0313  AC50 HEK-293T C210(0.94)  LDD0911  [2]
 LDCM0314  AC51 HEK-293T C210(1.01)  LDD0912  [2]
 LDCM0315  AC52 HEK-293T C210(1.24)  LDD0913  [2]
 LDCM0316  AC53 HEK-293T C210(1.34)  LDD0914  [2]
 LDCM0317  AC54 HEK-293T C210(1.17)  LDD0915  [2]
 LDCM0318  AC55 HEK-293T C210(2.09)  LDD0916  [2]
 LDCM0319  AC56 HEK-293T C210(1.95)  LDD0917  [2]
 LDCM0320  AC57 HEK-293T C210(0.79)  LDD0918  [2]
 LDCM0321  AC58 HEK-293T C210(0.78)  LDD0919  [2]
 LDCM0322  AC59 HEK-293T C210(0.50)  LDD0920  [2]
 LDCM0323  AC6 HEK-293T C210(0.91)  LDD0921  [2]
 LDCM0324  AC60 HEK-293T C210(1.15)  LDD0922  [2]
 LDCM0325  AC61 HEK-293T C210(0.73)  LDD0923  [2]
 LDCM0326  AC62 HEK-293T C210(0.65)  LDD0924  [2]
 LDCM0327  AC63 HEK-293T C210(0.74)  LDD0925  [2]
 LDCM0328  AC64 HEK-293T C210(0.74)  LDD0926  [2]
 LDCM0329  AC65 HEK-293T C210(0.96)  LDD0927  [2]
 LDCM0330  AC66 HEK-293T C210(0.79)  LDD0928  [2]
 LDCM0331  AC67 HEK-293T C210(0.83)  LDD0929  [2]
 LDCM0332  AC68 HEK-293T C210(1.04)  LDD0930  [2]
 LDCM0333  AC69 HEK-293T C210(0.88)  LDD0931  [2]
 LDCM0334  AC7 HEK-293T C210(1.05)  LDD0932  [2]
 LDCM0335  AC70 HEK-293T C210(1.44)  LDD0933  [2]
 LDCM0336  AC71 HEK-293T C210(1.11)  LDD0934  [2]
 LDCM0337  AC72 HEK-293T C210(1.04)  LDD0935  [2]
 LDCM0338  AC73 HEK-293T C210(1.06)  LDD0936  [2]
 LDCM0339  AC74 HEK-293T C210(1.67)  LDD0937  [2]
 LDCM0340  AC75 HEK-293T C210(1.68)  LDD0938  [2]
 LDCM0341  AC76 HEK-293T C210(1.22)  LDD0939  [2]
 LDCM0342  AC77 HEK-293T C210(1.45)  LDD0940  [2]
 LDCM0343  AC78 HEK-293T C210(1.08)  LDD0941  [2]
 LDCM0344  AC79 HEK-293T C210(1.50)  LDD0942  [2]
 LDCM0345  AC8 HEK-293T C210(1.11)  LDD0943  [2]
 LDCM0346  AC80 HEK-293T C210(1.82)  LDD0944  [2]
 LDCM0347  AC81 HEK-293T C210(1.96)  LDD0945  [2]
 LDCM0348  AC82 HEK-293T C210(2.12)  LDD0946  [2]
 LDCM0349  AC83 HEK-293T C210(0.69)  LDD0947  [2]
 LDCM0350  AC84 HEK-293T C210(0.99)  LDD0948  [2]
 LDCM0351  AC85 HEK-293T C210(0.94)  LDD0949  [2]
 LDCM0352  AC86 HEK-293T C210(0.97)  LDD0950  [2]
 LDCM0353  AC87 HEK-293T C210(1.17)  LDD0951  [2]
 LDCM0354  AC88 HEK-293T C210(1.06)  LDD0952  [2]
 LDCM0355  AC89 HEK-293T C210(1.16)  LDD0953  [2]
 LDCM0357  AC90 HEK-293T C210(0.88)  LDD0955  [2]
 LDCM0358  AC91 HEK-293T C210(0.77)  LDD0956  [2]
 LDCM0359  AC92 HEK-293T C210(0.72)  LDD0957  [2]
 LDCM0360  AC93 HEK-293T C210(0.82)  LDD0958  [2]
 LDCM0361  AC94 HEK-293T C210(1.28)  LDD0959  [2]
 LDCM0362  AC95 HEK-293T C210(1.09)  LDD0960  [2]
 LDCM0363  AC96 HEK-293T C210(1.03)  LDD0961  [2]
 LDCM0364  AC97 HEK-293T C210(1.47)  LDD0962  [2]
 LDCM0365  AC98 HEK-293T C210(1.55)  LDD0963  [2]
 LDCM0366  AC99 HEK-293T C210(1.36)  LDD0964  [2]
 LDCM0248  AKOS034007472 HEK-293T C210(1.38)  LDD0846  [2]
 LDCM0356  AKOS034007680 HEK-293T C210(1.41)  LDD0954  [2]
 LDCM0275  AKOS034007705 HEK-293T C210(1.27)  LDD0873  [2]
 LDCM0369  CL100 HEK-293T C210(1.08)  LDD0967  [2]
 LDCM0370  CL101 HEK-293T C210(0.98)  LDD0968  [2]
 LDCM0371  CL102 HEK-293T C210(1.11)  LDD0969  [2]
 LDCM0372  CL103 HEK-293T C210(0.98)  LDD0970  [2]
 LDCM0373  CL104 HEK-293T C210(1.08)  LDD0971  [2]
 LDCM0374  CL105 HEK-293T C210(0.68)  LDD0972  [2]
 LDCM0375  CL106 HEK-293T C210(0.71)  LDD0973  [2]
 LDCM0376  CL107 HEK-293T C210(1.01)  LDD0974  [2]
 LDCM0377  CL108 HEK-293T C210(1.22)  LDD0975  [2]
 LDCM0378  CL109 HEK-293T C210(1.12)  LDD0976  [2]
 LDCM0379  CL11 HEK-293T C210(0.97)  LDD1583  [4]
 LDCM0380  CL110 HEK-293T C210(1.07)  LDD0978  [2]
 LDCM0381  CL111 HEK-293T C210(0.98)  LDD0979  [2]
 LDCM0382  CL112 HEK-293T C210(0.69)  LDD0980  [2]
 LDCM0383  CL113 HEK-293T C210(0.65)  LDD0981  [2]
 LDCM0384  CL114 HEK-293T C210(0.77)  LDD0982  [2]
 LDCM0385  CL115 HEK-293T C210(1.00)  LDD0983  [2]
 LDCM0386  CL116 HEK-293T C210(0.90)  LDD0984  [2]
 LDCM0389  CL119 HEK-293T C258(0.97)  LDD1593  [4]
 LDCM0390  CL12 HEK-293T C258(1.29); C210(0.90)  LDD1594  [4]
 LDCM0391  CL120 HEK-293T C258(1.03); C210(0.79)  LDD1595  [4]
 LDCM0392  CL121 HEK-293T C210(1.60)  LDD0990  [2]
 LDCM0393  CL122 HEK-293T C210(1.62)  LDD0991  [2]
 LDCM0394  CL123 HEK-293T C210(1.60)  LDD0992  [2]
 LDCM0395  CL124 HEK-293T C210(1.90)  LDD0993  [2]
 LDCM0396  CL125 HEK-293T C210(0.78)  LDD0994  [2]
 LDCM0397  CL126 HEK-293T C210(0.68)  LDD0995  [2]
 LDCM0398  CL127 HEK-293T C210(0.90)  LDD0996  [2]
 LDCM0399  CL128 HEK-293T C210(0.87)  LDD0997  [2]
 LDCM0402  CL15 HEK-293T C258(0.83)  LDD1606  [4]
 LDCM0403  CL16 HEK-293T C210(0.54)  LDD1001  [2]
 LDCM0404  CL17 HEK-293T C210(0.79)  LDD1002  [2]
 LDCM0405  CL18 HEK-293T C210(0.69)  LDD1003  [2]
 LDCM0406  CL19 HEK-293T C210(1.02)  LDD1004  [2]
 LDCM0408  CL20 HEK-293T C210(1.09)  LDD1006  [2]
 LDCM0409  CL21 HEK-293T C210(1.76)  LDD1007  [2]
 LDCM0410  CL22 HEK-293T C210(0.58)  LDD1008  [2]
 LDCM0411  CL23 HEK-293T C210(0.73)  LDD1009  [2]
 LDCM0412  CL24 HEK-293T C210(0.83)  LDD1010  [2]
 LDCM0413  CL25 HEK-293T C210(0.72)  LDD1011  [2]
 LDCM0414  CL26 HEK-293T C210(0.69)  LDD1012  [2]
 LDCM0415  CL27 HEK-293T C210(1.28)  LDD1013  [2]
 LDCM0416  CL28 HEK-293T C210(1.00)  LDD1014  [2]
 LDCM0417  CL29 HEK-293T C210(0.94)  LDD1015  [2]
 LDCM0418  CL3 HEK-293T C258(1.10)  LDD1622  [4]
 LDCM0419  CL30 HEK-293T C210(0.70)  LDD1017  [2]
 LDCM0420  CL31 HEK-293T C258(1.27); C210(0.90)  LDD1624  [4]
 LDCM0422  CL33 HEK-293T C212(0.81)  LDD1626  [4]
 LDCM0424  CL35 HEK-293T C210(0.91)  LDD1628  [4]
 LDCM0425  CL36 HEK-293T C258(1.37); C210(1.03)  LDD1629  [4]
 LDCM0428  CL39 HEK-293T C258(1.01)  LDD1632  [4]
 LDCM0429  CL4 HEK-293T C258(1.02); C210(0.92)  LDD1633  [4]
 LDCM0430  CL40 HEK-293T C258(1.09); C210(0.89)  LDD1634  [4]
 LDCM0431  CL41 HEK-293T C180(1.16); C212(1.01)  LDD1635  [4]
 LDCM0432  CL42 HEK-293T C210(1.03)  LDD1636  [4]
 LDCM0433  CL43 HEK-293T C258(1.17); C210(0.94)  LDD1637  [4]
 LDCM0435  CL45 HEK-293T C212(0.85)  LDD1639  [4]
 LDCM0437  CL47 HEK-293T C210(0.93)  LDD1641  [4]
 LDCM0438  CL48 HEK-293T C258(1.27); C210(0.98)  LDD1642  [4]
 LDCM0440  CL5 HEK-293T C180(1.21); C212(1.17)  LDD1644  [4]
 LDCM0443  CL52 HEK-293T C258(1.03); C210(1.01)  LDD1646  [4]
 LDCM0444  CL53 HEK-293T C180(1.06); C212(2.01)  LDD1647  [4]
 LDCM0445  CL54 HEK-293T C210(1.15)  LDD1648  [4]
 LDCM0446  CL55 HEK-293T C258(1.07); C210(1.00)  LDD1649  [4]
 LDCM0448  CL57 HEK-293T C212(0.85)  LDD1651  [4]
 LDCM0450  CL59 HEK-293T C210(1.09)  LDD1653  [4]
 LDCM0451  CL6 HEK-293T C210(1.12)  LDD1654  [4]
 LDCM0452  CL60 HEK-293T C258(1.33); C210(1.13)  LDD1655  [4]
 LDCM0455  CL63 HEK-293T C258(1.12)  LDD1658  [4]
 LDCM0456  CL64 HEK-293T C258(1.01); C210(0.92)  LDD1659  [4]
 LDCM0457  CL65 HEK-293T C180(0.98); C212(1.11)  LDD1660  [4]
 LDCM0458  CL66 HEK-293T C210(0.94)  LDD1661  [4]
 LDCM0459  CL67 HEK-293T C258(1.12); C210(1.18)  LDD1662  [4]
 LDCM0461  CL69 HEK-293T C212(1.04)  LDD1664  [4]
 LDCM0462  CL7 HEK-293T C258(1.06); C210(0.96)  LDD1665  [4]
 LDCM0464  CL71 HEK-293T C210(1.16)  LDD1667  [4]
 LDCM0465  CL72 HEK-293T C258(1.40); C210(1.00)  LDD1668  [4]
 LDCM0469  CL76 HEK-293T C210(0.97)  LDD1067  [2]
 LDCM0470  CL77 HEK-293T C210(1.13)  LDD1068  [2]
 LDCM0471  CL78 HEK-293T C210(0.88)  LDD1069  [2]
 LDCM0472  CL79 HEK-293T C210(0.96)  LDD1070  [2]
 LDCM0474  CL80 HEK-293T C210(0.88)  LDD1072  [2]
 LDCM0475  CL81 HEK-293T C210(1.01)  LDD1073  [2]
 LDCM0476  CL82 HEK-293T C210(0.83)  LDD1074  [2]
 LDCM0477  CL83 HEK-293T C210(0.91)  LDD1075  [2]
 LDCM0478  CL84 HEK-293T C210(0.98)  LDD1076  [2]
 LDCM0479  CL85 HEK-293T C210(1.03)  LDD1077  [2]
 LDCM0480  CL86 HEK-293T C210(0.90)  LDD1078  [2]
 LDCM0481  CL87 HEK-293T C210(1.03)  LDD1079  [2]
 LDCM0482  CL88 HEK-293T C210(1.04)  LDD1080  [2]
 LDCM0483  CL89 HEK-293T C210(1.02)  LDD1081  [2]
 LDCM0484  CL9 HEK-293T C212(1.09)  LDD1687  [4]
 LDCM0485  CL90 HEK-293T C210(1.36)  LDD1083  [2]
 LDCM0486  CL91 HEK-293T C210(0.87)  LDD1084  [2]
 LDCM0487  CL92 HEK-293T C210(0.99)  LDD1085  [2]
 LDCM0488  CL93 HEK-293T C210(0.85)  LDD1086  [2]
 LDCM0489  CL94 HEK-293T C210(0.98)  LDD1087  [2]
 LDCM0490  CL95 HEK-293T C210(1.36)  LDD1088  [2]
 LDCM0491  CL96 HEK-293T C210(0.97)  LDD1089  [2]
 LDCM0492  CL97 HEK-293T C210(1.12)  LDD1090  [2]
 LDCM0493  CL98 HEK-293T C210(1.11)  LDD1091  [2]
 LDCM0494  CL99 HEK-293T C210(1.18)  LDD1092  [2]
 LDCM0495  E2913 HEK-293T C258(0.97)  LDD1698  [4]
 LDCM0625  F8 Ramos C258(1.47)  LDD2187  [5]
 LDCM0572  Fragment10 Ramos C258(1.55)  LDD2189  [5]
 LDCM0573  Fragment11 Ramos C258(5.21)  LDD2190  [5]
 LDCM0574  Fragment12 Ramos C258(0.83)  LDD2191  [5]
 LDCM0575  Fragment13 Ramos C258(1.13)  LDD2192  [5]
 LDCM0576  Fragment14 Ramos C258(1.02)  LDD2193  [5]
 LDCM0579  Fragment20 Ramos C258(0.82)  LDD2194  [5]
 LDCM0580  Fragment21 Ramos C258(1.27)  LDD2195  [5]
 LDCM0582  Fragment23 Ramos C258(0.58)  LDD2196  [5]
 LDCM0578  Fragment27 Ramos C258(1.14)  LDD2197  [5]
 LDCM0586  Fragment28 Ramos C258(1.51)  LDD2198  [5]
 LDCM0588  Fragment30 Ramos C258(1.19)  LDD2199  [5]
 LDCM0589  Fragment31 Ramos C258(0.71)  LDD2200  [5]
 LDCM0590  Fragment32 Ramos C258(2.72)  LDD2201  [5]
 LDCM0468  Fragment33 HEK-293T C258(0.93)  LDD1671  [4]
 LDCM0596  Fragment38 Ramos C258(1.39)  LDD2203  [5]
 LDCM0566  Fragment4 Ramos C258(1.34)  LDD2184  [5]
 LDCM0610  Fragment52 Ramos C258(1.33)  LDD2204  [5]
 LDCM0614  Fragment56 Ramos C258(1.08)  LDD2205  [5]
 LDCM0569  Fragment7 Ramos C258(1.42)  LDD2186  [5]
 LDCM0571  Fragment9 Ramos C258(0.95)  LDD2188  [5]
 LDCM0022  KB02 HCT 116 C258(2.83)  LDD0080  [2]
 LDCM0023  KB03 HCT 116 C258(1.34)  LDD0081  [2]
 LDCM0024  KB05 HCT 116 C258(1.35)  LDD0082  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2) 5'-AMP-activated protein kinase beta subunit family O43741
DNA-directed RNA polymerases I and III subunit RPAC1 (POLR1C) Archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family O15160
Glycogen [starch] synthase, muscle (GYS1) Glycosyltransferase 3 family P13807
Protein N-terminal glutamine amidohydrolase (NTAQ1) NTAQ1 family Q96HA8
Kinesin-like protein KIF9 (KIF9) Kinesin family Q9HAQ2
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cytochrome c oxidase subunit 5B, mitochondrial (COX5B) Cytochrome c oxidase subunit 5B family P10606
Sodium channel modifier 1 (SCNM1) . Q9BWG6
Other
Click To Hide/Show 12 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
ATP synthase mitochondrial F1 complex assembly factor 2 (ATPAF2) ATP12 family Q8N5M1
DNA mismatch repair protein Mlh1 (MLH1) DNA mismatch repair MutL/HexB family P40692
Probable RNA-binding protein EIF1AD (EIF1AD) EIF1AD family Q8N9N8
Protein FAM90A1 (FAM90A1) FAM90 family Q86YD7
DNA repair protein RAD51 homolog 4 (RAD51D) RecA family O75771
Protein S100-Z (S100Z) S-100 family Q8WXG8
Tektin-4 (TEKT4) Tektin family Q8WW24
Pre-rRNA-processing protein TSR2 homolog (TSR2) TSR2 family Q969E8
Armadillo repeat-containing protein 7 (ARMC7) . Q9H6L4
Heat shock factor 2-binding protein (HSF2BP) . O75031
Sprouty-related, EVH1 domain-containing protein 2 (SPRED2) . Q7Z698
TBC1 domain family member 22B (TBC1D22B) . Q9NU19

References

1 An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
4 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
5 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578