Details of the Target

General Information of Target

Target ID LDTP07029
Target Name Sterile alpha motif domain-containing protein 9 (SAMD9)
Gene Name SAMD9
Gene ID 54809
Synonyms
C7orf5; DRIF1; KIAA2004; OEF1; Sterile alpha motif domain-containing protein 9; SAM domain-containing protein 9
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAKQLNLPENTDDWTKEDVNQWLESHKIDQKHREILTEQDVNGAVLKWLKKEHLVDMGIT
HGPAIQIEELFKELRKTAIEDSIQTSKMGKPSKNAPKDQTVSQKERRETSKQKQKGKENP
DMANPSAMSTTAKGSKSLKVELIEDKIDYTKERQPSIDLTCVSYPFDEFSNPYRYKLDFS
LQPETGPGNLIDPIHEFKAFTNTATATEEDVKMKFSNEVFRFASACMNSRTNGTIHFGVK
DKPHGKIVGIKVTNDTKEALINHFNLMINKYFEDHQVQQAKKCIREPRFVEVLLPNSTLS
DRFVIEVDIIPQFSECQYDYFQIKMQNYNNKIWEQSKKFSLFVRDGTSSKDITKNKVDFR
AFKADFKTLAESRKAAEEKFRAKTNKKEREGPKLVKLLTGNQDLLDNSYYEQYILVTNKC
HPDQTKHLDFLKEIKWFAVLEFDPESNINGVVKAYKESRVANLHFPSVYVEQKTTPNETI
STLNLYHQPSWIFCNGRLDLDSEKYKPFDPSSWQRERASDVRKLISFLTHEDIMPRGKFL
VVFLLLSSVDDPRDPLIETFCAFYQDLKGMENILCICVHPHIFQGWKDLLEARLIKHQDE
ISSQCISALSLEEINGTILKLKSVTQSSKRLLPSIGLSTVLLKKEEDIMTALEIICENEC
EGTLLEKDKNKFLEFKASKEEDFYRGGKVSWWNFYFSSESYSSPFVKRDKYERLEAMIQN
CADSSKPTSTKIIHLYHHPGCGGTTLAMHILWELRKKFRCAVLKNKTVDFSEIGEQVTSL
ITYGAMNRQEYVPVLLLVDDFEEQDNVYLLQYSIQTAIAKKYIRYEKPLVIILNCMRSQN
PEKSARIPDSIAVIQQLSPKEQRAFELKLKEIKEQHKNFEDFYSFMIMKTNFNKEYIENV
VRNILKGQNIFTKEAKLFSFLALLNSYVPDTTISLSQCEKFLGIGNKKAFWGTEKFEDKM
GTYSTILIKTEVIECGNYCGVRIIHSLIAEFSLEELKKSYHLNKSQIMLDMLTENLFFDT
GMGKSKFLQDMHTLLLTRHRDEHEGETGNWFSPFIEALHKDEGNEAVEAVLLESIHRFNP
NAFICQALARHFYIKKKDFGNALNWAKQAKIIEPDNSYISDTLGQVYKSKIRWWIEENGG
NGNISVDDLIALLDLAEHASSAFKESQQQSEDREYEVKERLYPKSKRRYDTYNIAGYQGE
IEVGLYTIQILQLIPFFDNKNELSKRYMVNFVSGSSDIPGDPNNEYKLALKNYIPYLTKL
KFSLKKSFDFFDEYFVLLKPRNNIKQNEEAKTRRKVAGYFKKYVDIFCLLEESQNNTGLG
SKFSEPLQVERCRRNLVALKADKFSGLLEYLIKSQEDAISTMKCIVNEYTFLLEQCTVKI
QSKEKLNFILANIILSCIQPTSRLVKPVEKLKDQLREVLQPIGLTYQFSEPYFLASLLFW
PENQQLDQHSEQMKEYAQALKNSFKGQYKHMHRTKQPIAYFFLGKGKRLERLVHKGKIDQ
CFKKTPDINSLWQSGDVWKEEKVQELLLRLQGRAENNCLYIEYGINEKITIPITPAFLGQ
LRSGRSIEKVSFYLGFSIGGPLAYDIEIV
Target Bioclass
Other
Subcellular location
Cytoplasm
Function
Double-stranded nucleic acid binding that acts as an antiviral factor by playing an essential role in the formation of cytoplasmic antiviral granules. May play a role in the inflammatory response to tissue injury and the control of extra-osseous calcification, acting as a downstream target of TNF-alpha signaling. Involved in the regulation of EGR1, in coordination with RGL2. May be involved in endosome fusion.
Uniprot ID
Q5K651
Ensemble ID
ENST00000379958.3
HGNC ID
HGNC:1348

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 6 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		C721(2.09)  LDD1702  [1]
DBIA
 Probe Info  		C975(1.19); C979(1.19); C161(1.15); C1538(1.10)  LDD0078  [2]
4-Iodoacetamidophenylacetylene
 Probe Info  		C605(0.00); C721(0.00); C494(0.00); C1308(0.00)  LDD0038  [3]
IA-alkyne
 Probe Info  		C721(0.00); C938(0.00); C835(0.00); C1085(0.00)  LDD0036  [3]
Lodoacetamide azide
 Probe Info  		C226(0.00); C605(0.00); C721(0.00); C494(0.00)  LDD0037  [3]
STPyne
 Probe Info  		N.A.  LDD0009  [4]
PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STS-2
 Probe Info  		N.A.  LDD0139  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C1364(1.09); C1376(1.09)  LDD0531  [2]
 LDCM0246  AC128 HCT 116 C1364(1.48); C1376(1.48)  LDD0563  [2]
 LDCM0247  AC129 HCT 116 C1364(0.58); C1376(0.58)  LDD0564  [2]
 LDCM0249  AC130 HCT 116 C1364(1.01); C1376(1.01)  LDD0566  [2]
 LDCM0250  AC131 HCT 116 C1364(0.65); C1376(0.65)  LDD0567  [2]
 LDCM0251  AC132 HCT 116 C1364(0.91); C1376(0.91)  LDD0568  [2]
 LDCM0252  AC133 HCT 116 C1364(0.62); C1376(0.62)  LDD0569  [2]
 LDCM0253  AC134 HCT 116 C1364(0.78); C1376(0.78)  LDD0570  [2]
 LDCM0254  AC135 HCT 116 C1364(0.97); C1376(0.97)  LDD0571  [2]
 LDCM0255  AC136 HCT 116 C1364(0.71); C1376(0.71)  LDD0572  [2]
 LDCM0256  AC137 HCT 116 C1364(0.86); C1376(0.86)  LDD0573  [2]
 LDCM0257  AC138 HCT 116 C1364(0.82); C1376(0.82)  LDD0574  [2]
 LDCM0258  AC139 HCT 116 C1364(0.86); C1376(0.86)  LDD0575  [2]
 LDCM0260  AC140 HCT 116 C1364(0.90); C1376(0.90)  LDD0577  [2]
 LDCM0261  AC141 HCT 116 C1364(0.97); C1376(0.97)  LDD0578  [2]
 LDCM0262  AC142 HCT 116 C1364(0.89); C1376(0.89)  LDD0579  [2]
 LDCM0263  AC143 HCT 116 C1364(0.90); C1376(0.90); C226(1.00)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C226(0.85); C1364(1.03); C1376(1.03)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C1364(0.91); C1376(0.91); C226(0.94)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C226(0.97); C1364(1.52); C1376(1.52)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C226(0.94); C1364(1.26); C1376(1.26)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C226(1.14); C1364(1.58); C1376(1.58)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C226(0.97); C1364(1.07); C1376(1.07)  LDD0586  [2]
 LDCM0271  AC150 HCT 116 C1364(0.67); C1376(0.67); C226(1.58)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C1364(0.79); C1376(0.79); C226(1.00)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C226(0.71); C1364(1.65); C1376(1.65)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C226(1.01); C1364(1.24); C1376(1.24)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C1364(1.19); C1376(1.19); C226(0.88)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C1364(1.86); C1376(1.86); C226(0.53)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C1364(0.87); C1376(0.87); C226(0.82)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C1364(0.87); C1376(0.87); C226(0.63)  LDD2161  [2]
 LDCM0279  AC2 HCT 116 C1364(0.95); C1376(0.95)  LDD0596  [2]
 LDCM0285  AC25 HCT 116 C1364(0.61); C1376(0.61)  LDD0602  [2]
 LDCM0286  AC26 HCT 116 C1364(0.58); C1376(0.58)  LDD0603  [2]
 LDCM0287  AC27 HCT 116 C1364(0.59); C1376(0.59)  LDD0604  [2]
 LDCM0288  AC28 HCT 116 C1364(0.76); C1376(0.76)  LDD0605  [2]
 LDCM0289  AC29 HCT 116 C1364(0.53); C1376(0.53)  LDD0606  [2]
 LDCM0290  AC3 HCT 116 C1364(1.00); C1376(1.00)  LDD0607  [2]
 LDCM0291  AC30 HCT 116 C1364(0.75); C1376(0.75)  LDD0608  [2]
 LDCM0292  AC31 HCT 116 C1364(0.67); C1376(0.67)  LDD0609  [2]
 LDCM0293  AC32 HCT 116 C1364(0.84); C1376(0.84)  LDD0610  [2]
 LDCM0294  AC33 HCT 116 C1364(1.07); C1376(1.07)  LDD0611  [2]
 LDCM0295  AC34 HCT 116 C1364(0.71); C1376(0.71)  LDD0612  [2]
 LDCM0296  AC35 HCT 116 C226(1.67)  LDD0613  [2]
 LDCM0297  AC36 HCT 116 C226(1.70)  LDD0614  [2]
 LDCM0298  AC37 HCT 116 C226(1.58)  LDD0615  [2]
 LDCM0299  AC38 HCT 116 C226(1.26)  LDD0616  [2]
 LDCM0300  AC39 HCT 116 C226(1.42)  LDD0617  [2]
 LDCM0301  AC4 HCT 116 C1364(1.03); C1376(1.03)  LDD0618  [2]
 LDCM0302  AC40 HCT 116 C226(1.20)  LDD0619  [2]
 LDCM0303  AC41 HCT 116 C226(1.09)  LDD0620  [2]
 LDCM0304  AC42 HCT 116 C226(1.53)  LDD0621  [2]
 LDCM0305  AC43 HCT 116 C226(1.21)  LDD0622  [2]
 LDCM0306  AC44 HCT 116 C226(1.56)  LDD0623  [2]
 LDCM0307  AC45 HCT 116 C226(1.51)  LDD0624  [2]
 LDCM0308  AC46 HCT 116 C1538(0.85); C226(1.13)  LDD0625  [2]
 LDCM0309  AC47 HCT 116 C226(0.89); C1538(0.95)  LDD0626  [2]
 LDCM0310  AC48 HCT 116 C1538(0.87); C226(1.26)  LDD0627  [2]
 LDCM0311  AC49 HCT 116 C1538(0.99); C226(1.09)  LDD0628  [2]
 LDCM0312  AC5 HCT 116 C1364(1.03); C1376(1.03)  LDD0629  [2]
 LDCM0313  AC50 HCT 116 C1538(0.73); C226(1.28)  LDD0630  [2]
 LDCM0314  AC51 HCT 116 C1538(0.94); C226(1.18)  LDD0631  [2]
 LDCM0315  AC52 HCT 116 C1538(0.85); C226(1.01)  LDD0632  [2]
 LDCM0316  AC53 HCT 116 C1538(0.85); C226(1.21)  LDD0633  [2]
 LDCM0317  AC54 HCT 116 C1538(0.82); C226(0.99)  LDD0634  [2]
 LDCM0318  AC55 HCT 116 C226(1.01); C1538(1.14)  LDD0635  [2]
 LDCM0319  AC56 HCT 116 C1538(1.09); C226(1.27)  LDD0636  [2]
 LDCM0320  AC57 HCT 116 C226(1.08); C1538(1.42); C1364(1.77); C1376(1.77)  LDD0637  [2]
 LDCM0321  AC58 HCT 116 C226(0.81); C1364(1.42); C1376(1.42); C1538(1.71)  LDD0638  [2]
 LDCM0322  AC59 HCT 116 C226(0.99); C1364(1.53); C1376(1.53); C1538(1.57)  LDD0639  [2]
 LDCM0324  AC60 HCT 116 C226(1.07); C1538(1.56); C1364(1.75); C1376(1.75)  LDD0641  [2]
 LDCM0325  AC61 HCT 116 C1364(1.26); C1376(1.26); C226(1.37); C1538(1.54)  LDD0642  [2]
 LDCM0326  AC62 HCT 116 C226(0.76); C1538(1.65); C1364(1.89); C1376(1.89)  LDD0643  [2]
 LDCM0327  AC63 HCT 116 C226(1.07); C1538(1.44); C1364(1.48); C1376(1.48)  LDD0644  [2]
 LDCM0328  AC64 HCT 116 C226(1.05); C1364(1.70); C1376(1.70); C1538(1.87)  LDD0645  [2]
 LDCM0329  AC65 HCT 116 C226(0.83); C1538(1.76); C1364(2.15); C1376(2.15)  LDD0646  [2]
 LDCM0330  AC66 HCT 116 C226(0.90); C1538(1.74); C1364(1.87); C1376(1.87)  LDD0647  [2]
 LDCM0331  AC67 HCT 116 C226(0.73); C1538(1.52); C1364(1.78); C1376(1.78)  LDD0648  [2]
 LDCM0332  AC68 HCT 116 C226(0.87); C1364(1.15); C1376(1.15)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C226(1.04); C1364(1.20); C1376(1.20)  LDD0650  [2]
 LDCM0335  AC70 HCT 116 C226(0.88); C1364(1.10); C1376(1.10)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C1364(1.01); C1376(1.01); C226(1.11)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C1364(1.02); C1376(1.02); C226(1.09)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C226(1.28); C1364(1.91); C1376(1.91)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C1364(1.20); C1376(1.20); C226(1.53)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C1364(1.30); C1376(1.30); C226(1.44)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C226(0.95); C1364(1.25); C1376(1.25)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C1364(1.01); C1376(1.01); C226(1.08)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C1364(1.22); C1376(1.22); C226(1.32)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C226(0.97); C1364(1.11); C1376(1.11)  LDD0661  [2]
 LDCM0346  AC80 HCT 116 C1364(0.97); C1376(0.97); C226(1.25)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C1364(0.66); C1376(0.66); C226(1.42)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C1364(1.38); C1376(1.38); C226(1.47)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C1364(1.43); C1376(1.43)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C1364(1.33); C1376(1.33)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C1364(1.33); C1376(1.33)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C1364(1.31); C1376(1.31)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C1364(0.99); C1376(0.99)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C1364(1.42); C1376(1.42)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C1364(1.30); C1376(1.30)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C1364(1.41); C1376(1.41)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C1364(1.61); C1376(1.61)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C1364(1.79); C1376(1.79)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C1364(1.53); C1376(1.53)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C1364(1.78); C1376(1.78)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C1364(1.76); C1376(1.76)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C1364(1.85); C1376(1.85)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C1364(1.17); C1376(1.17)  LDD0681  [2]
 LDCM0020  ARS-1620 HCC44 C975(1.19); C979(1.19); C161(1.15); C1538(1.10)  LDD0078  [2]
 LDCM0367  CL1 HCT 116 C1364(0.72); C1376(0.72)  LDD0684  [2]
 LDCM0368  CL10 HCT 116 C1364(0.81); C1376(0.81)  LDD0685  [2]
 LDCM0369  CL100 HCT 116 C1364(1.04); C1376(1.04)  LDD0686  [2]
 LDCM0379  CL11 HCT 116 C1364(0.74); C1376(0.74)  LDD0696  [2]
 LDCM0382  CL112 HCT 116 C1364(0.52); C1376(0.52)  LDD0699  [2]
 LDCM0383  CL113 HCT 116 C1364(0.72); C1376(0.72)  LDD0700  [2]
 LDCM0384  CL114 HCT 116 C1364(0.56); C1376(0.56)  LDD0701  [2]
 LDCM0385  CL115 HCT 116 C1364(0.75); C1376(0.75)  LDD0702  [2]
 LDCM0386  CL116 HCT 116 C1364(0.61); C1376(0.61)  LDD0703  [2]
 LDCM0387  CL117 HCT 116 C226(1.51)  LDD0704  [2]
 LDCM0388  CL118 HCT 116 C226(1.11)  LDD0705  [2]
 LDCM0389  CL119 HCT 116 C226(1.07)  LDD0706  [2]
 LDCM0390  CL12 HCT 116 C1364(0.86); C1376(0.86)  LDD0707  [2]
 LDCM0391  CL120 HCT 116 C226(1.22)  LDD0708  [2]
 LDCM0392  CL121 HCT 116 C1538(0.96); C226(1.09)  LDD0709  [2]
 LDCM0393  CL122 HCT 116 C1538(1.20); C226(1.30)  LDD0710  [2]
 LDCM0394  CL123 HCT 116 C1538(0.53); C226(0.89)  LDD0711  [2]
 LDCM0395  CL124 HCT 116 C1538(0.82); C226(1.19)  LDD0712  [2]
 LDCM0396  CL125 HCT 116 C226(0.77); C1364(0.96); C1376(0.96); C1538(1.27)  LDD0713  [2]
 LDCM0397  CL126 HCT 116 C226(1.20); C1364(1.40); C1376(1.40); C1538(1.63)  LDD0714  [2]
 LDCM0398  CL127 HCT 116 C226(0.79); C1364(1.14); C1376(1.14); C1538(1.26)  LDD0715  [2]
 LDCM0399  CL128 HCT 116 C226(0.68); C1538(1.51); C1364(2.46); C1376(2.46)  LDD0716  [2]
 LDCM0400  CL13 HCT 116 C1364(1.28); C1376(1.28)  LDD0717  [2]
 LDCM0401  CL14 HCT 116 C1364(0.74); C1376(0.74)  LDD0718  [2]
 LDCM0402  CL15 HCT 116 C1364(0.97); C1376(0.97)  LDD0719  [2]
 LDCM0403  CL16 HCT 116 C1538(1.53)  LDD0720  [2]
 LDCM0404  CL17 HCT 116 C1538(0.93)  LDD0721  [2]
 LDCM0405  CL18 HCT 116 C1538(1.12)  LDD0722  [2]
 LDCM0406  CL19 HCT 116 C1538(0.98)  LDD0723  [2]
 LDCM0407  CL2 HCT 116 C1364(0.58); C1376(0.58)  LDD0724  [2]
 LDCM0408  CL20 HCT 116 C1538(1.05)  LDD0725  [2]
 LDCM0409  CL21 HCT 116 C1538(1.01)  LDD0726  [2]
 LDCM0410  CL22 HCT 116 C1538(1.27)  LDD0727  [2]
 LDCM0411  CL23 HCT 116 C1538(1.35)  LDD0728  [2]
 LDCM0412  CL24 HCT 116 C1538(1.40)  LDD0729  [2]
 LDCM0413  CL25 HCT 116 C1538(1.22)  LDD0730  [2]
 LDCM0414  CL26 HCT 116 C1538(1.02)  LDD0731  [2]
 LDCM0415  CL27 HCT 116 C1538(1.19)  LDD0732  [2]
 LDCM0416  CL28 HCT 116 C1538(1.29)  LDD0733  [2]
 LDCM0417  CL29 HCT 116 C1538(1.50)  LDD0734  [2]
 LDCM0418  CL3 HCT 116 C1364(0.70); C1376(0.70)  LDD0735  [2]
 LDCM0419  CL30 HCT 116 C1538(1.32)  LDD0736  [2]
 LDCM0420  CL31 HCT 116 C1364(1.02); C1376(1.02); C226(0.59)  LDD0737  [2]
 LDCM0421  CL32 HCT 116 C1364(1.07); C1376(1.07); C226(0.59)  LDD0738  [2]
 LDCM0422  CL33 HCT 116 C1364(0.92); C1376(0.92); C226(0.56)  LDD0739  [2]
 LDCM0423  CL34 HCT 116 C1364(0.96); C1376(0.96); C226(0.57)  LDD0740  [2]
 LDCM0424  CL35 HCT 116 C1364(1.24); C1376(1.24); C226(0.42)  LDD0741  [2]
 LDCM0425  CL36 HCT 116 C1364(1.11); C1376(1.11); C226(0.49)  LDD0742  [2]
 LDCM0426  CL37 HCT 116 C1364(1.23); C1376(1.23); C226(0.53)  LDD0743  [2]
 LDCM0428  CL39 HCT 116 C1364(1.36); C1376(1.36); C226(0.51)  LDD0745  [2]
 LDCM0429  CL4 HCT 116 C1364(1.45); C1376(1.45)  LDD0746  [2]
 LDCM0430  CL40 HCT 116 C1364(1.07); C1376(1.07); C226(0.43)  LDD0747  [2]
 LDCM0431  CL41 HCT 116 C1364(0.97); C1376(0.97); C226(0.71)  LDD0748  [2]
 LDCM0432  CL42 HCT 116 C1364(1.57); C1376(1.57); C226(0.65)  LDD0749  [2]
 LDCM0433  CL43 HCT 116 C1364(1.22); C1376(1.22); C226(0.69)  LDD0750  [2]
 LDCM0434  CL44 HCT 116 C1364(1.05); C1376(1.05); C226(0.74)  LDD0751  [2]
 LDCM0435  CL45 HCT 116 C1364(1.85); C1376(1.85); C226(0.71)  LDD0752  [2]
 LDCM0440  CL5 HCT 116 C1364(0.71); C1376(0.71)  LDD0757  [2]
 LDCM0451  CL6 HCT 116 C1364(0.96); C1376(0.96)  LDD0768  [2]
 LDCM0453  CL61 HCT 116 C1538(0.86)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C1538(0.88)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C1538(0.90)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C1538(2.03)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C1538(1.04)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C1538(0.96)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C1538(0.92)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C1538(0.91)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C1538(1.07)  LDD0778  [2]
 LDCM0462  CL7 HCT 116 C1364(0.97); C1376(0.97)  LDD0779  [2]
 LDCM0463  CL70 HCT 116 C1538(1.23)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C1538(1.47)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C1538(1.12)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C1538(0.87)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C1538(1.10)  LDD0784  [2]
 LDCM0473  CL8 HCT 116 C1364(0.84); C1376(0.84)  LDD0790  [2]
 LDCM0484  CL9 HCT 116 C1364(0.74); C1376(0.74)  LDD0801  [2]
 LDCM0486  CL91 HCT 116 C1364(1.04); C1376(1.04)  LDD0803  [2]
 LDCM0487  CL92 HCT 116 C1364(0.98); C1376(0.98)  LDD0804  [2]
 LDCM0488  CL93 HCT 116 C1364(0.89); C1376(0.89)  LDD0805  [2]
 LDCM0489  CL94 HCT 116 C1364(1.06); C1376(1.06)  LDD0806  [2]
 LDCM0490  CL95 HCT 116 C1364(1.14); C1376(1.14)  LDD0807  [2]
 LDCM0491  CL96 HCT 116 C1364(1.19); C1376(1.19)  LDD0808  [2]
 LDCM0492  CL97 HCT 116 C1364(1.22); C1376(1.22)  LDD0809  [2]
 LDCM0493  CL98 HCT 116 C1364(1.07); C1376(1.07)  LDD0810  [2]
 LDCM0494  CL99 HCT 116 C1364(1.14); C1376(1.14)  LDD0811  [2]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C721(2.09)  LDD1702  [1]
 LDCM0468  Fragment33 HCT 116 C1538(1.17)  LDD0785  [2]
 LDCM0427  Fragment51 HCT 116 C1364(1.40); C1376(1.40); C226(0.58)  LDD0744  [2]
 LDCM0022  KB02 42-MG-BA C1538(1.51)  LDD2244  [6]
 LDCM0023  KB03 42-MG-BA C1538(2.20)  LDD2661  [6]
 LDCM0024  KB05 G361 C1538(1.16); C1085(2.70)  LDD3311  [6]
 LDCM0021  THZ1 HCT 116 C1364(1.21); C1376(1.21)  LDD2173  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Early endosome antigen 1 (EEA1) . Q15075

References

1 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
4 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
5 Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8551-6. doi: 10.1002/anie.201300683. Epub 2013 Jun 10.
6 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840