Details of the Target

General Information of Target

Target ID LDTP04383
Target Name Ras association domain-containing protein 2 (RASSF2)
Gene Name RASSF2
Gene ID 9770
Synonyms
CENP-34; KIAA0168; Ras association domain-containing protein 2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MDYSHQTSLVPCGQDKYISKNELLLHLKTYNLYYEGQNLQLRHREEEDEFIVEGLLNISW
GLRRPIRLQMQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAPPEGDQ
MPSSTDSRGLKPLQEDTPQLMRTRSDVGVRRRGNVRTPSDQRRIRRHRFSINGHFYNHKT
SVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKATDY
PLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKK
LMRKYTVLRLMIRQRLEEIAETPATI
Target Bioclass
Other
Subcellular location
Nucleus
Function Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
Uniprot ID
P50749
Ensemble ID
ENST00000379376.2
HGNC ID
HGNC:9883

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HL60 SNV: p.I58V .
NCIH2052 SNV: p.E294Ter .
RPMI7951 SNV: p.R152C .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 12 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C251(2.62)  LDD3338  [1]
HHS-475
 Probe Info  		Y270(1.51)  LDD0264  [2]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [3]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [3]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [3]
WYneN
 Probe Info  		N.A.  LDD0021  [4]
WYneO
 Probe Info  		N.A.  LDD0022  [4]
Compound 10
 Probe Info  		C251(0.00); C90(0.00)  LDD2216  [5]
Compound 11
 Probe Info  		N.A.  LDD2213  [5]
IPM
 Probe Info  		N.A.  LDD0005  [4]
YN-1
 Probe Info  		N.A.  LDD0446  [6]
AOyne
 Probe Info  		15.00  LDD0443  [7]
PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
VE-P
 Probe Info  		N.A.  LDD0396  [8]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C251(1.02)  LDD1507  [9]
 LDCM0215  AC10 HEK-293T C251(0.98)  LDD1508  [9]
 LDCM0237  AC12 HEK-293T C251(0.99)  LDD1510  [9]
 LDCM0259  AC14 HEK-293T C251(0.96)  LDD1512  [9]
 LDCM0270  AC15 HEK-293T C251(0.93)  LDD1513  [9]
 LDCM0276  AC17 HEK-293T C251(0.95)  LDD1515  [9]
 LDCM0277  AC18 HEK-293T C251(1.03)  LDD1516  [9]
 LDCM0279  AC2 HEK-293T C251(0.98)  LDD1518  [9]
 LDCM0280  AC20 HEK-293T C251(0.96)  LDD1519  [9]
 LDCM0281  AC21 HEK-293T C251(0.98)  LDD1520  [9]
 LDCM0282  AC22 HEK-293T C251(1.00)  LDD1521  [9]
 LDCM0283  AC23 HEK-293T C251(0.93)  LDD1522  [9]
 LDCM0284  AC24 HEK-293T C251(1.02)  LDD1523  [9]
 LDCM0285  AC25 HEK-293T C251(0.96)  LDD1524  [9]
 LDCM0286  AC26 HEK-293T C251(1.00)  LDD1525  [9]
 LDCM0288  AC28 HEK-293T C251(0.98)  LDD1527  [9]
 LDCM0289  AC29 HEK-293T C251(0.97)  LDD1528  [9]
 LDCM0291  AC30 HEK-293T C251(0.96)  LDD1530  [9]
 LDCM0292  AC31 HEK-293T C251(0.97)  LDD1531  [9]
 LDCM0293  AC32 HEK-293T C251(0.95)  LDD1532  [9]
 LDCM0294  AC33 HEK-293T C251(0.91)  LDD1533  [9]
 LDCM0295  AC34 HEK-293T C251(0.95)  LDD1534  [9]
 LDCM0297  AC36 HEK-293T C251(0.94)  LDD1536  [9]
 LDCM0298  AC37 HEK-293T C251(0.90)  LDD1537  [9]
 LDCM0299  AC38 HEK-293T C251(0.98)  LDD1538  [9]
 LDCM0300  AC39 HEK-293T C251(0.94)  LDD1539  [9]
 LDCM0301  AC4 HEK-293T C251(0.97)  LDD1540  [9]
 LDCM0302  AC40 HEK-293T C251(0.93)  LDD1541  [9]
 LDCM0303  AC41 HEK-293T C251(1.02)  LDD1542  [9]
 LDCM0304  AC42 HEK-293T C251(1.05)  LDD1543  [9]
 LDCM0306  AC44 HEK-293T C251(1.00)  LDD1545  [9]
 LDCM0307  AC45 HEK-293T C251(1.03)  LDD1546  [9]
 LDCM0308  AC46 HEK-293T C251(1.04)  LDD1547  [9]
 LDCM0309  AC47 HEK-293T C251(0.94)  LDD1548  [9]
 LDCM0310  AC48 HEK-293T C251(0.95)  LDD1549  [9]
 LDCM0311  AC49 HEK-293T C251(1.02)  LDD1550  [9]
 LDCM0312  AC5 HEK-293T C251(0.91)  LDD1551  [9]
 LDCM0313  AC50 HEK-293T C251(1.04)  LDD1552  [9]
 LDCM0315  AC52 HEK-293T C251(1.00)  LDD1554  [9]
 LDCM0316  AC53 HEK-293T C251(0.92)  LDD1555  [9]
 LDCM0317  AC54 HEK-293T C251(0.98)  LDD1556  [9]
 LDCM0318  AC55 HEK-293T C251(0.90)  LDD1557  [9]
 LDCM0319  AC56 HEK-293T C251(0.89)  LDD1558  [9]
 LDCM0320  AC57 HEK-293T C251(1.05)  LDD1559  [9]
 LDCM0321  AC58 HEK-293T C251(1.00)  LDD1560  [9]
 LDCM0323  AC6 HEK-293T C251(1.11)  LDD1562  [9]
 LDCM0324  AC60 HEK-293T C251(1.06)  LDD1563  [9]
 LDCM0325  AC61 HEK-293T C251(0.98)  LDD1564  [9]
 LDCM0326  AC62 HEK-293T C251(0.98)  LDD1565  [9]
 LDCM0327  AC63 HEK-293T C251(0.97)  LDD1566  [9]
 LDCM0328  AC64 HEK-293T C251(0.97)  LDD1567  [9]
 LDCM0334  AC7 HEK-293T C251(0.93)  LDD1568  [9]
 LDCM0345  AC8 HEK-293T C251(0.93)  LDD1569  [9]
 LDCM0248  AKOS034007472 HEK-293T C251(0.96)  LDD1511  [9]
 LDCM0356  AKOS034007680 HEK-293T C251(0.99)  LDD1570  [9]
 LDCM0275  AKOS034007705 HEK-293T C251(0.92)  LDD1514  [9]
 LDCM0367  CL1 HEK-293T C251(1.04)  LDD1571  [9]
 LDCM0368  CL10 HEK-293T C251(1.79)  LDD1572  [9]
 LDCM0369  CL100 HEK-293T C251(1.02)  LDD1573  [9]
 LDCM0370  CL101 HEK-293T C251(1.01)  LDD1574  [9]
 LDCM0371  CL102 HEK-293T C251(1.04)  LDD1575  [9]
 LDCM0372  CL103 HEK-293T C251(0.97)  LDD1576  [9]
 LDCM0373  CL104 HEK-293T C251(0.99)  LDD1577  [9]
 LDCM0374  CL105 HEK-293T C251(1.02)  LDD1578  [9]
 LDCM0375  CL106 HEK-293T C251(0.96)  LDD1579  [9]
 LDCM0376  CL107 HEK-293T C251(0.92)  LDD1580  [9]
 LDCM0377  CL108 HEK-293T C251(0.97)  LDD1581  [9]
 LDCM0378  CL109 HEK-293T C251(1.11)  LDD1582  [9]
 LDCM0379  CL11 HEK-293T C251(0.92)  LDD1583  [9]
 LDCM0380  CL110 HEK-293T C251(0.89)  LDD1584  [9]
 LDCM0381  CL111 HEK-293T C251(1.00)  LDD1585  [9]
 LDCM0382  CL112 HEK-293T C251(1.01)  LDD1586  [9]
 LDCM0383  CL113 HEK-293T C251(1.05)  LDD1587  [9]
 LDCM0384  CL114 HEK-293T C251(1.02)  LDD1588  [9]
 LDCM0385  CL115 HEK-293T C251(0.98)  LDD1589  [9]
 LDCM0386  CL116 HEK-293T C251(0.95)  LDD1590  [9]
 LDCM0387  CL117 HEK-293T C251(1.10)  LDD1591  [9]
 LDCM0388  CL118 HEK-293T C251(1.04)  LDD1592  [9]
 LDCM0389  CL119 HEK-293T C251(0.96)  LDD1593  [9]
 LDCM0390  CL12 HEK-293T C251(1.00)  LDD1594  [9]
 LDCM0391  CL120 HEK-293T C251(1.00)  LDD1595  [9]
 LDCM0392  CL121 HEK-293T C251(1.01)  LDD1596  [9]
 LDCM0393  CL122 HEK-293T C251(0.97)  LDD1597  [9]
 LDCM0394  CL123 HEK-293T C251(0.90)  LDD1598  [9]
 LDCM0395  CL124 HEK-293T C251(0.98)  LDD1599  [9]
 LDCM0396  CL125 HEK-293T C251(1.04)  LDD1600  [9]
 LDCM0397  CL126 HEK-293T C251(0.97)  LDD1601  [9]
 LDCM0398  CL127 HEK-293T C251(0.98)  LDD1602  [9]
 LDCM0399  CL128 HEK-293T C251(0.97)  LDD1603  [9]
 LDCM0400  CL13 HEK-293T C251(1.09)  LDD1604  [9]
 LDCM0401  CL14 HEK-293T C251(0.91)  LDD1605  [9]
 LDCM0402  CL15 HEK-293T C251(1.07)  LDD1606  [9]
 LDCM0403  CL16 HEK-293T C251(0.95)  LDD1607  [9]
 LDCM0404  CL17 HEK-293T C251(1.05)  LDD1608  [9]
 LDCM0405  CL18 HEK-293T C251(1.04)  LDD1609  [9]
 LDCM0407  CL2 HEK-293T C251(1.16)  LDD1611  [9]
 LDCM0408  CL20 HEK-293T C251(0.97)  LDD1612  [9]
 LDCM0409  CL21 HEK-293T C251(1.12)  LDD1613  [9]
 LDCM0410  CL22 HEK-293T C251(1.09)  LDD1614  [9]
 LDCM0411  CL23 HEK-293T C251(1.01)  LDD1615  [9]
 LDCM0412  CL24 HEK-293T C251(1.02)  LDD1616  [9]
 LDCM0413  CL25 HEK-293T C251(0.99)  LDD1617  [9]
 LDCM0414  CL26 HEK-293T C251(0.89)  LDD1618  [9]
 LDCM0415  CL27 HEK-293T C251(0.95)  LDD1619  [9]
 LDCM0416  CL28 HEK-293T C251(0.98)  LDD1620  [9]
 LDCM0417  CL29 HEK-293T C251(0.92)  LDD1621  [9]
 LDCM0418  CL3 HEK-293T C251(1.00)  LDD1622  [9]
 LDCM0419  CL30 HEK-293T C251(1.02)  LDD1623  [9]
 LDCM0421  CL32 HEK-293T C251(0.95)  LDD1625  [9]
 LDCM0422  CL33 HEK-293T C251(1.19)  LDD1626  [9]
 LDCM0423  CL34 HEK-293T C251(1.16)  LDD1627  [9]
 LDCM0424  CL35 HEK-293T C251(1.14)  LDD1628  [9]
 LDCM0425  CL36 HEK-293T C251(1.02)  LDD1629  [9]
 LDCM0426  CL37 HEK-293T C251(0.85)  LDD1630  [9]
 LDCM0428  CL39 HEK-293T C251(1.10)  LDD1632  [9]
 LDCM0429  CL4 HEK-293T C251(0.98)  LDD1633  [9]
 LDCM0430  CL40 HEK-293T C251(0.96)  LDD1634  [9]
 LDCM0431  CL41 HEK-293T C251(0.97)  LDD1635  [9]
 LDCM0432  CL42 HEK-293T C251(1.03)  LDD1636  [9]
 LDCM0434  CL44 HEK-293T C251(0.94)  LDD1638  [9]
 LDCM0435  CL45 HEK-293T C251(1.11)  LDD1639  [9]
 LDCM0436  CL46 HEK-293T C251(1.12)  LDD1640  [9]
 LDCM0437  CL47 HEK-293T C251(1.15)  LDD1641  [9]
 LDCM0438  CL48 HEK-293T C251(1.00)  LDD1642  [9]
 LDCM0439  CL49 HEK-293T C251(0.98)  LDD1643  [9]
 LDCM0440  CL5 HEK-293T C251(1.03)  LDD1644  [9]
 LDCM0441  CL50 HEK-293T C251(0.96)  LDD1645  [9]
 LDCM0443  CL52 HEK-293T C251(0.98)  LDD1646  [9]
 LDCM0444  CL53 HEK-293T C251(1.12)  LDD1647  [9]
 LDCM0445  CL54 HEK-293T C251(0.98)  LDD1648  [9]
 LDCM0447  CL56 HEK-293T C251(0.98)  LDD1650  [9]
 LDCM0448  CL57 HEK-293T C251(1.48)  LDD1651  [9]
 LDCM0449  CL58 HEK-293T C251(1.22)  LDD1652  [9]
 LDCM0450  CL59 HEK-293T C251(0.97)  LDD1653  [9]
 LDCM0451  CL6 HEK-293T C251(1.06)  LDD1654  [9]
 LDCM0452  CL60 HEK-293T C251(1.00)  LDD1655  [9]
 LDCM0453  CL61 HEK-293T C251(0.96)  LDD1656  [9]
 LDCM0454  CL62 HEK-293T C251(1.06)  LDD1657  [9]
 LDCM0455  CL63 HEK-293T C251(0.96)  LDD1658  [9]
 LDCM0456  CL64 HEK-293T C251(1.05)  LDD1659  [9]
 LDCM0457  CL65 HEK-293T C251(0.94)  LDD1660  [9]
 LDCM0458  CL66 HEK-293T C251(1.11)  LDD1661  [9]
 LDCM0460  CL68 HEK-293T C251(0.93)  LDD1663  [9]
 LDCM0461  CL69 HEK-293T C251(0.97)  LDD1664  [9]
 LDCM0463  CL70 HEK-293T C251(1.00)  LDD1666  [9]
 LDCM0464  CL71 HEK-293T C251(1.07)  LDD1667  [9]
 LDCM0465  CL72 HEK-293T C251(0.99)  LDD1668  [9]
 LDCM0466  CL73 HEK-293T C251(1.22)  LDD1669  [9]
 LDCM0467  CL74 HEK-293T C251(0.96)  LDD1670  [9]
 LDCM0469  CL76 HEK-293T C251(1.02)  LDD1672  [9]
 LDCM0470  CL77 HEK-293T C251(0.95)  LDD1673  [9]
 LDCM0471  CL78 HEK-293T C251(1.04)  LDD1674  [9]
 LDCM0473  CL8 HEK-293T C251(1.74)  LDD1676  [9]
 LDCM0474  CL80 HEK-293T C251(0.99)  LDD1677  [9]
 LDCM0475  CL81 HEK-293T C251(0.90)  LDD1678  [9]
 LDCM0476  CL82 HEK-293T C251(0.97)  LDD1679  [9]
 LDCM0477  CL83 HEK-293T C251(0.97)  LDD1680  [9]
 LDCM0478  CL84 HEK-293T C251(1.04)  LDD1681  [9]
 LDCM0479  CL85 HEK-293T C251(1.11)  LDD1682  [9]
 LDCM0480  CL86 HEK-293T C251(0.98)  LDD1683  [9]
 LDCM0481  CL87 HEK-293T C251(0.92)  LDD1684  [9]
 LDCM0482  CL88 HEK-293T C251(1.06)  LDD1685  [9]
 LDCM0483  CL89 HEK-293T C251(1.05)  LDD1686  [9]
 LDCM0484  CL9 HEK-293T C251(0.93)  LDD1687  [9]
 LDCM0485  CL90 HEK-293T C251(1.24)  LDD1688  [9]
 LDCM0487  CL92 HEK-293T C251(1.03)  LDD1690  [9]
 LDCM0488  CL93 HEK-293T C251(1.00)  LDD1691  [9]
 LDCM0489  CL94 HEK-293T C251(1.08)  LDD1692  [9]
 LDCM0490  CL95 HEK-293T C251(1.18)  LDD1693  [9]
 LDCM0491  CL96 HEK-293T C251(1.04)  LDD1694  [9]
 LDCM0492  CL97 HEK-293T C251(1.15)  LDD1695  [9]
 LDCM0493  CL98 HEK-293T C251(0.97)  LDD1696  [9]
 LDCM0494  CL99 HEK-293T C251(1.06)  LDD1697  [9]
 LDCM0495  E2913 HEK-293T C251(1.09)  LDD1698  [9]
 LDCM0625  F8 Ramos C251(1.16); C90(2.89)  LDD2187  [10]
 LDCM0572  Fragment10 Ramos C251(8.33)  LDD2189  [10]
 LDCM0573  Fragment11 Ramos C251(0.43)  LDD2190  [10]
 LDCM0574  Fragment12 Ramos C251(1.80); C90(1.73)  LDD2191  [10]
 LDCM0575  Fragment13 Ramos C251(1.01); C90(0.62)  LDD2192  [10]
 LDCM0576  Fragment14 Ramos C251(1.16); C90(0.93)  LDD2193  [10]
 LDCM0579  Fragment20 Ramos C251(1.82)  LDD2194  [10]
 LDCM0580  Fragment21 Ramos C251(1.03); C90(0.61)  LDD2195  [10]
 LDCM0582  Fragment23 Ramos C251(1.07); C90(1.70)  LDD2196  [10]
 LDCM0578  Fragment27 Ramos C251(0.86); C90(1.33)  LDD2197  [10]
 LDCM0586  Fragment28 Ramos C251(1.91); C90(1.07)  LDD2198  [10]
 LDCM0588  Fragment30 Ramos C251(1.46); C90(8.99)  LDD2199  [10]
 LDCM0589  Fragment31 Ramos C251(0.90); C90(0.70)  LDD2200  [10]
 LDCM0590  Fragment32 Ramos C251(11.10)  LDD2201  [10]
 LDCM0468  Fragment33 HEK-293T C251(0.82)  LDD1671  [9]
 LDCM0596  Fragment38 Ramos C251(1.06)  LDD2203  [10]
 LDCM0566  Fragment4 Ramos C251(2.70); C90(1.33)  LDD2184  [10]
 LDCM0427  Fragment51 HEK-293T C251(0.93)  LDD1631  [9]
 LDCM0610  Fragment52 Ramos C251(1.90); C90(2.13)  LDD2204  [10]
 LDCM0614  Fragment56 Ramos C251(1.34); C90(0.95)  LDD2205  [10]
 LDCM0569  Fragment7 Ramos C251(1.86); C90(2.65)  LDD2186  [10]
 LDCM0571  Fragment9 Ramos C251(2.25); C90(1.31)  LDD2188  [10]
 LDCM0116  HHS-0101 DM93 Y270(1.51)  LDD0264  [2]
 LDCM0117  HHS-0201 DM93 Y270(1.84)  LDD0265  [2]
 LDCM0118  HHS-0301 DM93 Y270(1.40)  LDD0266  [2]
 LDCM0119  HHS-0401 DM93 Y270(1.33)  LDD0267  [2]
 LDCM0120  HHS-0701 DM93 Y270(12.49)  LDD0268  [2]
 LDCM0022  KB02 HEK-293T C251(0.91)  LDD1492  [9]
 LDCM0023  KB03 HEK-293T C251(0.96)  LDD1497  [9]
 LDCM0024  KB05 MV4-11 C251(2.62)  LDD3338  [1]
 LDCM0131  RA190 MM1.R C251(1.16)  LDD0304  [11]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 8 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (DLST) 2-oxoacid dehydrogenase family P36957
Protein arginine N-methyltransferase 6 (PRMT6) Protein arginine N-methyltransferase family Q96LA8
Histone-lysine N-methyltransferase SUV39H1 (SUV39H1) Histone-lysine methyltransferase family O43463
Lysine-specific histone demethylase 1A (KDM1A) Flavin monoamine oxidase family O60341
Serine/threonine-protein kinase Nek7 (NEK7) NEK Ser/Thr protein kinase family Q8TDX7
Serine/threonine-protein kinase 3 (STK3) STE Ser/Thr protein kinase family Q13188
Serine/threonine-protein kinase 4 (STK4) STE Ser/Thr protein kinase family Q13043
GTPase KRas (KRAS) Ras family P01116
Transporter and channel
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Calreticulin (CALR) Calreticulin family P27797
Huntingtin (HTT) Huntingtin family P42858
Junctophilin-3 (JPH3) Junctophilin family Q8WXH2
Optineurin (OPTN) . Q96CV9
Other
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Glial fibrillary acidic protein (GFAP) Intermediate filament family P14136
Protein S100-Z (S100Z) S-100 family Q8WXG8
Ras association domain-containing protein 5 (RASSF5) . Q8WWW0

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
3 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
4 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
5 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
6 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
7 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
8 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
9 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
10 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
11 Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.