General Information of Experiment

Probe Name C279  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 7 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 79.3
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 41.9
 LDTP04211  Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) 20.0
 LDTP01333  Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) 14.4
 LDTP13058  Thioredoxin domain-containing protein 16 (TXNDC16) 6.7
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 6.5
 LDTP05493  Sulfotransferase 2A1 (SULT2A1) 5.8
Transporter and channel
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04502  Importin subunit alpha-5 (KPNA1) 7.5
 LDTP00865  Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) 6.6
 LDTP02010  Annexin A1 (ANXA1) 6.1
Other
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP05960  Trophoblast glycoprotein (TPBG) 18.1
 LDTP15623  Neuferricin (CYB5D2) 16.4
 LDTP00105  Protein unc-119 homolog B (UNC119B) 13.5
 LDTP01075  Protein CutA (CUTA) 7.1

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587