General Information of Experiment

Probe Name C241  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 6 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP06750  Prolyl 3-hydroxylase 1 (P3H1) 22.2
 LDTP00907  Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) 9.6
 LDTP08979  Prostaglandin reductase 2 (PTGR2) 7.4
 LDTP00575  Glutathione S-transferase A4 (GSTA4) 6.4
 LDTP03394  Ceramide synthase 1 (CERS1) 5.8
 LDTP05758  S-methyl-5'-thioadenosine phosphorylase (MTAP) 5.8
Transporter and channel
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00865  Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) 6.7
Other
Click to Show/Hide to Show 6 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 10.9
 LDTP15623  Neuferricin (CYB5D2) 9.3
 LDTP00105  Protein unc-119 homolog B (UNC119B) 9.1
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 5.9
 LDTP04355  Rab GDP dissociation inhibitor beta (GDI2) 5.3
 LDTP19372  Tetratricopeptide repeat protein 38 (TTC38) 4.9

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587