Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C024  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 6 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03198  Ferrochelatase, mitochondrial (FECH) 17.5
 LDTP12253  Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) 6.1
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 6.1
 LDTP03560  Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) 6.1
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 5.9
 LDTP01419  Retinal dehydrogenase 2 (ALDH1A2) 5.5
Transporter and channel
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 11.0
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 5.7
 LDTP07462  MFS-type transporter SLC18B1 (SLC18B1) 5.1
 LDTP17641  Solute carrier family 35 member F2 (SLC35F2) 4.9
Other
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP19372  Tetratricopeptide repeat protein 38 (TTC38) 13.4
 LDTP04094  Large proline-rich protein BAG6 (BAG6) 7.7
 LDTP08000  Dymeclin (DYM) 5.1

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587