Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | IA-alkyne | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 100 uM | |||||
| Criteria | Quantification: Probe vs (Probe+Competitor) | |||||
| Quantitative Method |
TMT
|
|||||
| Competitor Name | EV-99 | Competitor Info | ||||
| Competitor Concentration | 20 uM | |||||
| In Vivo Experiment Model | Model Type |
|
Cell lysate | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cell lysate (T cell) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP13219 | GTPase IMAP family member 2 (GIMAP2) | C261 | 20.0 | |||
| LDTP03540 | Heme oxygenase 2 (HMOX2) | C282 | 20.0 | |||
| LDTP04414 | Tyrosine-protein kinase Blk (BLK) | C319 | 20.0 | |||
| LDTP05128 | Glutathione S-transferase omega-1 (GSTO1) | C32 | 17.7 | |||
| LDTP08564 | E3 ubiquitin-protein ligase UBR1 (UBR1) | C1603 | 15.7 | |||
| LDTP11617 | Myotubularin-related protein 12 (MTMR12) | C152 | 15.4 | |||
| LDTP09598 | Mitochondrial coenzyme A diphosphatase NUDT8 (NUDT8) | C207 | 14.2 | |||
| LDTP12040 | Prostaglandin E synthase 2 (PTGES2) | C110 | 10.6 | |||
| LDTP00577 | Dihydroxyacetone phosphate acyltransferase (GNPAT) | C54 | 8.5 | |||
| LDTP03458 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38) | C296 | 6.5 | |||
| LDTP07640 | NAD(+) hydrolase SARM1 (SARM1) | C311 | 5.4 | |||
| LDTP04573 | LIM domain kinase 1 (LIMK1) | C349 | 4.5 | |||
Transporter and channel
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP10378 | Nuclear envelope pore membrane protein POM 121 (POM121) | C28 | 9.1 | |||
| LDTP14173 | Sorting nexin-8 (SNX8) | C192, C200 | 6.9 | |||
Other
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP14047 | Plexin-D1 (PLXND1) | C1363 | 20.0 | |||
| LDTP05257 | Receptor expression-enhancing protein 5 (REEP5) | C18 | 11.3 | |||
| LDTP13402 | Dynactin subunit 4 (DCTN4) | C258 | 8.1 | |||
| LDTP00941 | Zinc finger C3H1 domain-containing protein (ZFC3H1) | C1778 | 8.0 | |||
| LDTP03994 | Condensin-2 complex subunit D3 (NCAPD3) | C631 | 6.3 | |||
| LDTP08248 | NLR family member X1 (NLRX1) | C331 | 5.3 | |||
| LDTP13721 | TBC1 domain family member 2B (TBC1D2B) | C726 | 4.1 | |||