Details of the Target

General Information of Target

Target ID LDTP19227
Target Name Transmembrane protein 267 (TMEM267)
Gene Name TMEM267
Gene ID 64417
Synonyms
C5orf28; Transmembrane protein 267
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
Download
Sequence
MSPLRPLLLALALASVPCAQGACPASADLKHSDGTRTCAKLYDKSDPYYENCCGGAELSL
ESGADLPYLPSNWANTASSLVVAPRCELTVWSRQGKAGKTHKFSAGTYPRLEEYRRGILG
DWSNAISALYCRCS
Target Bioclass
Other
Subcellular location
Membrane
Uniprot ID
Q0VDI3
Ensemble ID
ENST00000397080.8
HGNC ID
HGNC:26139

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C168(0.97)  LDD0531  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C168(0.97)  LDD0531  [1]
 LDCM0230  AC113 HCT 116 C168(0.84)  LDD0547  [1]
 LDCM0231  AC114 HCT 116 C168(0.72)  LDD0548  [1]
 LDCM0232  AC115 HCT 116 C168(0.84)  LDD0549  [1]
 LDCM0233  AC116 HCT 116 C168(0.70)  LDD0550  [1]
 LDCM0234  AC117 HCT 116 C168(0.68)  LDD0551  [1]
 LDCM0235  AC118 HCT 116 C168(0.74)  LDD0552  [1]
 LDCM0236  AC119 HCT 116 C168(0.74)  LDD0553  [1]
 LDCM0238  AC120 HCT 116 C168(1.02)  LDD0555  [1]
 LDCM0239  AC121 HCT 116 C168(0.73)  LDD0556  [1]
 LDCM0240  AC122 HCT 116 C168(0.69)  LDD0557  [1]
 LDCM0241  AC123 HCT 116 C168(0.72)  LDD0558  [1]
 LDCM0242  AC124 HCT 116 C168(0.63)  LDD0559  [1]
 LDCM0243  AC125 HCT 116 C168(0.90)  LDD0560  [1]
 LDCM0244  AC126 HCT 116 C168(0.84)  LDD0561  [1]
 LDCM0245  AC127 HCT 116 C168(0.81)  LDD0562  [1]
 LDCM0263  AC143 HCT 116 C168(0.96)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C168(0.96)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C168(1.02)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C168(0.85)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C168(1.00)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C168(0.96)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C168(1.01)  LDD0586  [1]
 LDCM0271  AC150 HCT 116 C168(0.93)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C168(1.25)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C168(1.00)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C168(0.79)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C168(0.91)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C168(0.92)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C168(0.88)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C168(0.83)  LDD2161  [1]
 LDCM0276  AC17 HCT 116 C168(1.20)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C168(1.30)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C168(1.41)  LDD0595  [1]
 LDCM0279  AC2 HCT 116 C168(0.99)  LDD0596  [1]
 LDCM0280  AC20 HCT 116 C168(1.54)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C168(1.51)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C168(1.25)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C168(1.88)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C168(1.39)  LDD0601  [1]
 LDCM0285  AC25 HCT 116 C168(0.86)  LDD0602  [1]
 LDCM0286  AC26 HCT 116 C168(0.81)  LDD0603  [1]
 LDCM0287  AC27 HCT 116 C168(0.85)  LDD0604  [1]
 LDCM0288  AC28 HCT 116 C168(1.00)  LDD0605  [1]
 LDCM0289  AC29 HCT 116 C168(0.91)  LDD0606  [1]
 LDCM0290  AC3 HCT 116 C168(0.95)  LDD0607  [1]
 LDCM0291  AC30 HCT 116 C168(1.02)  LDD0608  [1]
 LDCM0292  AC31 HCT 116 C168(0.91)  LDD0609  [1]
 LDCM0293  AC32 HCT 116 C168(0.97)  LDD0610  [1]
 LDCM0294  AC33 HCT 116 C168(0.95)  LDD0611  [1]
 LDCM0295  AC34 HCT 116 C168(0.91)  LDD0612  [1]
 LDCM0296  AC35 HCT 116 C168(0.66)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C168(0.74)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C168(0.70)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C168(0.80)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C168(0.74)  LDD0617  [1]
 LDCM0301  AC4 HCT 116 C168(1.02)  LDD0618  [1]
 LDCM0302  AC40 HCT 116 C168(0.80)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C168(1.04)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C168(1.13)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C168(1.03)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C168(0.86)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C168(0.91)  LDD0624  [1]
 LDCM0312  AC5 HCT 116 C168(1.02)  LDD0629  [1]
 LDCM0332  AC68 HCT 116 C168(1.10)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C168(1.10)  LDD0650  [1]
 LDCM0335  AC70 HCT 116 C168(0.93)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C168(1.02)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C168(0.94)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C168(0.97)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C168(1.07)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C168(1.00)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C168(1.05)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C168(1.23)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C168(1.07)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C168(0.94)  LDD0661  [1]
 LDCM0346  AC80 HCT 116 C168(1.13)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C168(0.95)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C168(1.19)  LDD0665  [1]
 LDCM0349  AC83 HCT 116 C168(1.32)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C168(1.35)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C168(1.07)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C168(1.28)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C168(1.03)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C168(1.02)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C168(1.12)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C168(1.16)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C168(1.01)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C168(1.11)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C168(1.11)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C168(1.01)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C168(1.00)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C168(1.00)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C168(1.08)  LDD0681  [1]
 LDCM0367  CL1 HCT 116 C168(1.64)  LDD0684  [1]
 LDCM0368  CL10 HCT 116 C168(1.16)  LDD0685  [1]
 LDCM0369  CL100 HCT 116 C168(0.99)  LDD0686  [1]
 LDCM0374  CL105 HCT 116 C168(1.91)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C168(2.18)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C168(1.13)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C168(1.50)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C168(2.07)  LDD0695  [1]
 LDCM0379  CL11 HCT 116 C168(1.39)  LDD0696  [1]
 LDCM0380  CL110 HCT 116 C168(1.45)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C168(1.97)  LDD0698  [1]
 LDCM0382  CL112 HCT 116 C168(1.14)  LDD0699  [1]
 LDCM0383  CL113 HCT 116 C168(1.16)  LDD0700  [1]
 LDCM0384  CL114 HCT 116 C168(1.43)  LDD0701  [1]
 LDCM0385  CL115 HCT 116 C168(1.06)  LDD0702  [1]
 LDCM0386  CL116 HCT 116 C168(0.89)  LDD0703  [1]
 LDCM0387  CL117 HCT 116 C168(1.43)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C168(0.96)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C168(0.91)  LDD0706  [1]
 LDCM0390  CL12 HCT 116 C168(0.94)  LDD0707  [1]
 LDCM0391  CL120 HCT 116 C168(0.84)  LDD0708  [1]
 LDCM0400  CL13 HCT 116 C168(1.17)  LDD0717  [1]
 LDCM0401  CL14 HCT 116 C168(1.29)  LDD0718  [1]
 LDCM0402  CL15 HCT 116 C168(1.74)  LDD0719  [1]
 LDCM0403  CL16 HCT 116 C168(1.19)  LDD0720  [1]
 LDCM0404  CL17 HCT 116 C168(1.75)  LDD0721  [1]
 LDCM0405  CL18 HCT 116 C168(0.95)  LDD0722  [1]
 LDCM0406  CL19 HCT 116 C168(1.04)  LDD0723  [1]
 LDCM0407  CL2 HCT 116 C168(1.11)  LDD0724  [1]
 LDCM0408  CL20 HCT 116 C168(0.95)  LDD0725  [1]
 LDCM0409  CL21 HCT 116 C168(1.99)  LDD0726  [1]
 LDCM0410  CL22 HCT 116 C168(1.65)  LDD0727  [1]
 LDCM0411  CL23 HCT 116 C168(1.08)  LDD0728  [1]
 LDCM0412  CL24 HCT 116 C168(0.96)  LDD0729  [1]
 LDCM0413  CL25 HCT 116 C168(1.81)  LDD0730  [1]
 LDCM0414  CL26 HCT 116 C168(1.20)  LDD0731  [1]
 LDCM0415  CL27 HCT 116 C168(1.04)  LDD0732  [1]
 LDCM0416  CL28 HCT 116 C168(1.49)  LDD0733  [1]
 LDCM0417  CL29 HCT 116 C168(1.00)  LDD0734  [1]
 LDCM0418  CL3 HCT 116 C168(1.67)  LDD0735  [1]
 LDCM0419  CL30 HCT 116 C168(1.10)  LDD0736  [1]
 LDCM0420  CL31 HCT 116 C168(1.02)  LDD0737  [1]
 LDCM0429  CL4 HCT 116 C168(1.63)  LDD0746  [1]
 LDCM0436  CL46 HCT 116 C168(1.61)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C168(1.31)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C168(1.39)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C168(1.20)  LDD0756  [1]
 LDCM0440  CL5 HCT 116 C168(0.82)  LDD0757  [1]
 LDCM0441  CL50 HCT 116 C168(1.33)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C168(1.34)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C168(1.61)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C168(1.15)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C168(1.69)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C168(1.45)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C168(1.05)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C168(1.24)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C168(1.45)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C168(1.02)  LDD0767  [1]
 LDCM0451  CL6 HCT 116 C168(1.67)  LDD0768  [1]
 LDCM0452  CL60 HCT 116 C168(1.31)  LDD0769  [1]
 LDCM0453  CL61 HCT 116 C168(1.32)  LDD0770  [1]
 LDCM0454  CL62 HCT 116 C168(1.41)  LDD0771  [1]
 LDCM0455  CL63 HCT 116 C168(2.92)  LDD0772  [1]
 LDCM0456  CL64 HCT 116 C168(1.19)  LDD0773  [1]
 LDCM0457  CL65 HCT 116 C168(1.24)  LDD0774  [1]
 LDCM0458  CL66 HCT 116 C168(1.60)  LDD0775  [1]
 LDCM0459  CL67 HCT 116 C168(1.26)  LDD0776  [1]
 LDCM0460  CL68 HCT 116 C168(2.45)  LDD0777  [1]
 LDCM0461  CL69 HCT 116 C168(2.45)  LDD0778  [1]
 LDCM0462  CL7 HCT 116 C168(0.90)  LDD0779  [1]
 LDCM0463  CL70 HCT 116 C168(1.33)  LDD0780  [1]
 LDCM0464  CL71 HCT 116 C168(1.72)  LDD0781  [1]
 LDCM0465  CL72 HCT 116 C168(1.22)  LDD0782  [1]
 LDCM0466  CL73 HCT 116 C168(2.48)  LDD0783  [1]
 LDCM0467  CL74 HCT 116 C168(1.38)  LDD0784  [1]
 LDCM0469  CL76 HCT 116 C168(1.00)  LDD0786  [1]
 LDCM0470  CL77 HCT 116 C168(1.03)  LDD0787  [1]
 LDCM0471  CL78 HCT 116 C168(1.48)  LDD0788  [1]
 LDCM0472  CL79 HCT 116 C168(1.00)  LDD0789  [1]
 LDCM0473  CL8 HCT 116 C168(2.05)  LDD0790  [1]
 LDCM0474  CL80 HCT 116 C168(0.85)  LDD0791  [1]
 LDCM0475  CL81 HCT 116 C168(0.92)  LDD0792  [1]
 LDCM0476  CL82 HCT 116 C168(0.87)  LDD0793  [1]
 LDCM0477  CL83 HCT 116 C168(1.10)  LDD0794  [1]
 LDCM0478  CL84 HCT 116 C168(1.31)  LDD0795  [1]
 LDCM0479  CL85 HCT 116 C168(0.90)  LDD0796  [1]
 LDCM0480  CL86 HCT 116 C168(0.95)  LDD0797  [1]
 LDCM0481  CL87 HCT 116 C168(1.06)  LDD0798  [1]
 LDCM0482  CL88 HCT 116 C168(1.04)  LDD0799  [1]
 LDCM0483  CL89 HCT 116 C168(1.05)  LDD0800  [1]
 LDCM0484  CL9 HCT 116 C168(1.51)  LDD0801  [1]
 LDCM0485  CL90 HCT 116 C168(1.28)  LDD0802  [1]
 LDCM0486  CL91 HCT 116 C168(1.07)  LDD0803  [1]
 LDCM0487  CL92 HCT 116 C168(1.25)  LDD0804  [1]
 LDCM0488  CL93 HCT 116 C168(1.24)  LDD0805  [1]
 LDCM0489  CL94 HCT 116 C168(1.12)  LDD0806  [1]
 LDCM0490  CL95 HCT 116 C168(1.57)  LDD0807  [1]
 LDCM0491  CL96 HCT 116 C168(1.30)  LDD0808  [1]
 LDCM0492  CL97 HCT 116 C168(1.48)  LDD0809  [1]
 LDCM0493  CL98 HCT 116 C168(1.25)  LDD0810  [1]
 LDCM0494  CL99 HCT 116 C168(0.99)  LDD0811  [1]
 LDCM0468  Fragment33 HCT 116 C168(1.80)  LDD0785  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
GTP-binding protein SAR1a (SAR1A) SAR1 family Q9NR31
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Transmembrane protein 14B (TMEM14B) TMEM14 family Q9NUH8
Other
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Complexin-4 (CPLX4) Complexin/synaphin family Q7Z7G2
Syntaxin-7 (STX7) Syntaxin family O15400
Receptor-transporting protein 2 (RTP2) TMEM7 family Q5QGT7
Transmembrane protein 52B (TMEM52B) . Q4KMG9

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.