Details of the Target

General Information of Target

Target ID LDTP18308
Target Name CDK5 and ABL1 enzyme substrate 2 (CABLES2)
Gene Name CABLES2
Gene ID 81928
Synonyms
C20orf150; CDK5 and ABL1 enzyme substrate 2; Interactor with CDK3 2; Ik3-2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSEARGEPGSGPEAGARFFCTAGRGLEPFVMREVRARLAATQVEYISGKVFFTTCSDLNM
LKKLKSAERLFLLIKKQFPLIISSVSKGKIFNEMQRLINEDPGSWLNAISIWKNLLELDA
KKEKLSQRDDNQLKRKVGENEIIAKKLKIEQMQKIEENRDCQLEKQIKEETLEQRDFTTK
SEKFQEEEFQNDIEKAIDTHNQNDLTFRVSCRCSGTIGKAFTAQEVGKVIGIAIMKHFGW
KADLRNPQLEIFIHLNDIYSVVGIPVFRVSLASRAYIKTAGLRSTIAWAMASLADIKAGA
FVLDPMCGLGTILLEAAKEWPDVYYVGADVSDSQLLGTWDNLKAAGLEDKIELLKISVIE
LPLPSESVDIIISDIPFGKKFKLGKDIKSILQEMERVLHVGGTIVLLLSEDHHRRLTDCK
ESNIPFNSKDSHTDEPGIKKCLNPEEKTGAFKTASTSFEASNHKFLDRMSPFGSLVPVEC
YKVSLGKTDAFICKYKKSHSSGL
Target Bioclass
Other
Family
Cyclin family
Function Unknown. Probably involved in G1-S cell cycle transition.
Uniprot ID
Q9BTV7
Ensemble ID
ENST00000279101.10
HGNC ID
HGNC:16143

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C129(1.06); C140(1.06)  LDD0078  [1]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [2]
IA-alkyne
 Probe Info  		C773(0.00); C406(0.00)  LDD0161  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C129(1.10); C140(1.10)  LDD0531  [1]
 LDCM0215  AC10 HEK-293T C129(1.10); C140(1.10)  LDD0813  [1]
 LDCM0216  AC100 HCT 116 C129(0.78); C140(0.78)  LDD0533  [1]
 LDCM0217  AC101 HCT 116 C129(0.98); C140(0.98)  LDD0534  [1]
 LDCM0218  AC102 HCT 116 C129(0.63); C140(0.63)  LDD0535  [1]
 LDCM0219  AC103 HCT 116 C129(0.86); C140(0.86)  LDD0536  [1]
 LDCM0220  AC104 HCT 116 C129(0.86); C140(0.86)  LDD0537  [1]
 LDCM0221  AC105 HCT 116 C129(1.00); C140(1.00)  LDD0538  [1]
 LDCM0222  AC106 HCT 116 C129(0.92); C140(0.92)  LDD0539  [1]
 LDCM0223  AC107 HCT 116 C129(0.93); C140(0.93)  LDD0540  [1]
 LDCM0224  AC108 HCT 116 C129(0.58); C140(0.58)  LDD0541  [1]
 LDCM0225  AC109 HCT 116 C129(0.69); C140(0.69)  LDD0542  [1]
 LDCM0226  AC11 HEK-293T C129(1.31); C140(1.31)  LDD0824  [1]
 LDCM0227  AC110 HCT 116 C129(0.62); C140(0.62)  LDD0544  [1]
 LDCM0228  AC111 HCT 116 C129(0.72); C140(0.72)  LDD0545  [1]
 LDCM0229  AC112 HCT 116 C129(0.97); C140(0.97)  LDD0546  [1]
 LDCM0230  AC113 HEK-293T C129(1.37); C140(1.37)  LDD0828  [1]
 LDCM0231  AC114 HEK-293T C129(1.17); C140(1.17)  LDD0829  [1]
 LDCM0232  AC115 HEK-293T C129(1.22); C140(1.22)  LDD0830  [1]
 LDCM0233  AC116 HEK-293T C129(1.01); C140(1.01)  LDD0831  [1]
 LDCM0234  AC117 HEK-293T C129(1.14); C140(1.14)  LDD0832  [1]
 LDCM0235  AC118 HEK-293T C129(0.81); C140(0.81)  LDD0833  [1]
 LDCM0236  AC119 HEK-293T C129(1.39); C140(1.39)  LDD0834  [1]
 LDCM0237  AC12 HEK-293T C129(1.13); C140(1.13)  LDD0835  [1]
 LDCM0238  AC120 HEK-293T C129(1.20); C140(1.20)  LDD0836  [1]
 LDCM0239  AC121 HEK-293T C129(1.36); C140(1.36)  LDD0837  [1]
 LDCM0240  AC122 HEK-293T C129(1.24); C140(1.24)  LDD0838  [1]
 LDCM0241  AC123 HEK-293T C129(1.19); C140(1.19)  LDD0839  [1]
 LDCM0242  AC124 HEK-293T C129(1.46); C140(1.46)  LDD0840  [1]
 LDCM0243  AC125 HEK-293T C129(1.24); C140(1.24)  LDD0841  [1]
 LDCM0244  AC126 HEK-293T C129(1.38); C140(1.38)  LDD0842  [1]
 LDCM0245  AC127 HEK-293T C129(1.23); C140(1.23)  LDD0843  [1]
 LDCM0259  AC14 HEK-293T C129(0.95); C140(0.95)  LDD0857  [1]
 LDCM0263  AC143 HEK-293T C129(0.91); C140(0.91)  LDD0861  [1]
 LDCM0264  AC144 HEK-293T C129(0.90); C140(0.90)  LDD0862  [1]
 LDCM0265  AC145 HEK-293T C129(0.82); C140(0.82)  LDD0863  [1]
 LDCM0266  AC146 HEK-293T C129(0.84); C140(0.84)  LDD0864  [1]
 LDCM0267  AC147 HEK-293T C129(0.76); C140(0.76)  LDD0865  [1]
 LDCM0268  AC148 HEK-293T C129(0.78); C140(0.78)  LDD0866  [1]
 LDCM0269  AC149 HEK-293T C129(1.19); C140(1.19)  LDD0867  [1]
 LDCM0270  AC15 HEK-293T C129(1.04); C140(1.04)  LDD0868  [1]
 LDCM0271  AC150 HEK-293T C129(0.96); C140(0.96)  LDD0869  [1]
 LDCM0272  AC151 HEK-293T C129(1.04); C140(1.04)  LDD0870  [1]
 LDCM0273  AC152 HEK-293T C129(1.04); C140(1.04)  LDD0871  [1]
 LDCM0274  AC153 HEK-293T C129(0.88); C140(0.88)  LDD0872  [1]
 LDCM0621  AC154 HEK-293T C129(0.93); C140(0.93)  LDD2162  [1]
 LDCM0622  AC155 HEK-293T C129(0.94); C140(0.94)  LDD2163  [1]
 LDCM0623  AC156 HEK-293T C129(1.09); C140(1.09)  LDD2164  [1]
 LDCM0624  AC157 HEK-293T C129(0.93); C140(0.93)  LDD2165  [1]
 LDCM0276  AC17 HCT 116 C129(0.81); C140(0.81)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C129(0.76); C140(0.76)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C129(0.86); C140(0.86)  LDD0595  [1]
 LDCM0279  AC2 HCT 116 C129(1.33); C140(1.33)  LDD0596  [1]
 LDCM0280  AC20 HCT 116 C129(0.86); C140(0.86)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C129(0.79); C140(0.79)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C129(0.93); C140(0.93)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C129(0.80); C140(0.80)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C129(0.66); C140(0.66)  LDD0601  [1]
 LDCM0285  AC25 HEK-293T C181(1.10)  LDD1524  [4]
 LDCM0286  AC26 HEK-293T C181(0.97)  LDD1525  [4]
 LDCM0287  AC27 HEK-293T C181(0.99)  LDD1526  [4]
 LDCM0288  AC28 HEK-293T C181(0.91)  LDD1527  [4]
 LDCM0289  AC29 HEK-293T C181(1.08)  LDD1528  [4]
 LDCM0290  AC3 HCT 116 C129(1.21); C140(1.21)  LDD0607  [1]
 LDCM0291  AC30 HEK-293T C181(0.87)  LDD1530  [4]
 LDCM0292  AC31 HEK-293T C181(1.06)  LDD1531  [4]
 LDCM0293  AC32 HEK-293T C181(1.01)  LDD1532  [4]
 LDCM0294  AC33 HEK-293T C181(0.97)  LDD1533  [4]
 LDCM0295  AC34 HEK-293T C181(1.20)  LDD1534  [4]
 LDCM0296  AC35 PaTu 8988t C129(1.43); C140(1.43)  LDD1175  [1]
 LDCM0297  AC36 PaTu 8988t C129(1.51); C140(1.51)  LDD1176  [1]
 LDCM0298  AC37 PaTu 8988t C129(1.74); C140(1.74)  LDD1177  [1]
 LDCM0299  AC38 PaTu 8988t C129(1.43); C140(1.43)  LDD1178  [1]
 LDCM0300  AC39 PaTu 8988t C129(1.42); C140(1.42)  LDD1179  [1]
 LDCM0301  AC4 HCT 116 C129(0.87); C140(0.87)  LDD0618  [1]
 LDCM0302  AC40 PaTu 8988t C129(1.67); C140(1.67)  LDD1181  [1]
 LDCM0303  AC41 PaTu 8988t C129(1.49); C140(1.49)  LDD1182  [1]
 LDCM0304  AC42 PaTu 8988t C129(1.98); C140(1.98)  LDD1183  [1]
 LDCM0305  AC43 PaTu 8988t C129(1.39); C140(1.39)  LDD1184  [1]
 LDCM0306  AC44 PaTu 8988t C129(2.09); C140(2.09)  LDD1185  [1]
 LDCM0307  AC45 PaTu 8988t C129(1.79); C140(1.79)  LDD1186  [1]
 LDCM0308  AC46 PaTu 8988t C129(0.81); C140(0.81)  LDD1187  [1]
 LDCM0309  AC47 PaTu 8988t C129(0.81); C140(0.81)  LDD1188  [1]
 LDCM0310  AC48 PaTu 8988t C129(0.96); C140(0.96)  LDD1189  [1]
 LDCM0311  AC49 PaTu 8988t C129(1.40); C140(1.40)  LDD1190  [1]
 LDCM0312  AC5 HCT 116 C129(1.03); C140(1.03)  LDD0629  [1]
 LDCM0313  AC50 PaTu 8988t C129(1.16); C140(1.16)  LDD1192  [1]
 LDCM0314  AC51 PaTu 8988t C129(0.31); C140(0.31)  LDD1193  [1]
 LDCM0315  AC52 PaTu 8988t C129(0.95); C140(0.95)  LDD1194  [1]
 LDCM0316  AC53 PaTu 8988t C129(1.27); C140(1.27)  LDD1195  [1]
 LDCM0317  AC54 PaTu 8988t C129(1.17); C140(1.17)  LDD1196  [1]
 LDCM0318  AC55 PaTu 8988t C129(0.81); C140(0.81)  LDD1197  [1]
 LDCM0319  AC56 PaTu 8988t C129(0.84); C140(0.84)  LDD1198  [1]
 LDCM0320  AC57 HCT 116 C129(1.17); C140(1.17)  LDD0637  [1]
 LDCM0321  AC58 HCT 116 C129(1.54); C140(1.54)  LDD0638  [1]
 LDCM0322  AC59 HCT 116 C129(1.55); C140(1.55)  LDD0639  [1]
 LDCM0323  AC6 HEK-293T C129(0.97); C140(0.97)  LDD0921  [1]
 LDCM0324  AC60 HCT 116 C129(1.89); C140(1.89)  LDD0641  [1]
 LDCM0325  AC61 HCT 116 C129(1.87); C140(1.87)  LDD0642  [1]
 LDCM0326  AC62 HCT 116 C129(1.56); C140(1.56)  LDD0643  [1]
 LDCM0327  AC63 HCT 116 C129(1.85); C140(1.85)  LDD0644  [1]
 LDCM0328  AC64 HCT 116 C129(2.30); C140(2.30)  LDD0645  [1]
 LDCM0329  AC65 HCT 116 C129(1.87); C140(1.87)  LDD0646  [1]
 LDCM0330  AC66 HCT 116 C129(1.54); C140(1.54)  LDD0647  [1]
 LDCM0331  AC67 HCT 116 C129(1.53); C140(1.53)  LDD0648  [1]
 LDCM0332  AC68 HCT 116 C129(1.11); C140(1.11)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C129(1.14); C140(1.14)  LDD0650  [1]
 LDCM0334  AC7 HEK-293T C129(0.95); C140(0.95)  LDD0932  [1]
 LDCM0335  AC70 HCT 116 C129(0.91); C140(0.91)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C129(1.02); C140(1.02)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C129(1.46); C140(1.46)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C129(1.65); C140(1.65)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C129(1.62); C140(1.62)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C129(1.95); C140(1.95)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C129(1.50); C140(1.50)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C129(1.79); C140(1.79)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C129(1.20); C140(1.20)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C129(1.14); C140(1.14)  LDD0661  [1]
 LDCM0345  AC8 HEK-293T C129(0.84); C140(0.84)  LDD0943  [1]
 LDCM0346  AC80 HCT 116 C129(1.34); C140(1.34)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C129(0.99); C140(0.99)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C129(1.20); C140(1.20)  LDD0665  [1]
 LDCM0349  AC83 HEK-293T C129(0.84)  LDD0947  [1]
 LDCM0350  AC84 HEK-293T C129(0.66)  LDD0948  [1]
 LDCM0351  AC85 HEK-293T C129(0.71)  LDD0949  [1]
 LDCM0352  AC86 HEK-293T C129(0.89)  LDD0950  [1]
 LDCM0353  AC87 HEK-293T C129(0.69)  LDD0951  [1]
 LDCM0354  AC88 HEK-293T C129(0.82)  LDD0952  [1]
 LDCM0355  AC89 HEK-293T C129(1.09)  LDD0953  [1]
 LDCM0357  AC90 HEK-293T C129(0.88)  LDD0955  [1]
 LDCM0358  AC91 HEK-293T C129(1.06)  LDD0956  [1]
 LDCM0359  AC92 HEK-293T C129(0.87)  LDD0957  [1]
 LDCM0360  AC93 HEK-293T C129(1.25)  LDD0958  [1]
 LDCM0361  AC94 HEK-293T C129(1.04)  LDD0959  [1]
 LDCM0362  AC95 HEK-293T C129(0.98)  LDD0960  [1]
 LDCM0363  AC96 HEK-293T C129(1.17)  LDD0961  [1]
 LDCM0364  AC97 HEK-293T C129(1.36)  LDD0962  [1]
 LDCM0365  AC98 HCT 116 C129(1.00); C140(1.00)  LDD0682  [1]
 LDCM0366  AC99 HCT 116 C129(0.56); C140(0.56)  LDD0683  [1]
 LDCM0248  AKOS034007472 HEK-293T C129(0.89); C140(0.89)  LDD0846  [1]
 LDCM0356  AKOS034007680 HEK-293T C129(1.08); C140(1.08)  LDD0954  [1]
 LDCM0275  AKOS034007705 HEK-293T C129(1.39); C140(1.39)  LDD0873  [1]
 LDCM0020  ARS-1620 HCC44 C129(1.06); C140(1.06)  LDD0078  [1]
 LDCM0367  CL1 HCT 116 C129(0.95); C140(0.95)  LDD0684  [1]
 LDCM0368  CL10 HCT 116 C129(1.41); C140(1.41)  LDD0685  [1]
 LDCM0369  CL100 HCT 116 C129(1.29); C140(1.29)  LDD0686  [1]
 LDCM0370  CL101 HEK-293T C129(0.82); C140(0.82)  LDD0968  [1]
 LDCM0371  CL102 HEK-293T C129(1.08); C140(1.08)  LDD0969  [1]
 LDCM0372  CL103 HEK-293T C129(0.86); C140(0.86)  LDD0970  [1]
 LDCM0373  CL104 HEK-293T C129(1.00); C140(1.00)  LDD0971  [1]
 LDCM0374  CL105 HCT 116 C129(0.72); C140(0.72)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C129(0.79); C140(0.79)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C129(0.82); C140(0.82)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C129(0.89); C140(0.89)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C129(0.84); C140(0.84)  LDD0695  [1]
 LDCM0379  CL11 HCT 116 C129(1.38); C140(1.38)  LDD0696  [1]
 LDCM0380  CL110 HCT 116 C129(0.92); C140(0.92)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C129(0.90); C140(0.90)  LDD0698  [1]
 LDCM0382  CL112 HEK-293T C181(0.97)  LDD1586  [4]
 LDCM0383  CL113 HEK-293T C181(1.04)  LDD1587  [4]
 LDCM0384  CL114 HEK-293T C181(0.91)  LDD1588  [4]
 LDCM0385  CL115 HEK-293T C181(1.19)  LDD1589  [4]
 LDCM0386  CL116 HEK-293T C181(1.00)  LDD1590  [4]
 LDCM0387  CL117 PaTu 8988t C129(2.03); C140(2.03)  LDD1266  [1]
 LDCM0388  CL118 PaTu 8988t C129(1.55); C140(1.55)  LDD1267  [1]
 LDCM0389  CL119 PaTu 8988t C129(1.88); C140(1.88)  LDD1268  [1]
 LDCM0390  CL12 HCT 116 C129(1.28); C140(1.28)  LDD0707  [1]
 LDCM0391  CL120 PaTu 8988t C129(1.62); C140(1.62)  LDD1270  [1]
 LDCM0392  CL121 PaTu 8988t C129(1.01); C140(1.01)  LDD1271  [1]
 LDCM0393  CL122 PaTu 8988t C129(1.00); C140(1.00)  LDD1272  [1]
 LDCM0394  CL123 PaTu 8988t C129(0.82); C140(0.82)  LDD1273  [1]
 LDCM0395  CL124 PaTu 8988t C129(0.97); C140(0.97)  LDD1274  [1]
 LDCM0396  CL125 HCT 116 C129(1.40); C140(1.40)  LDD0713  [1]
 LDCM0397  CL126 HCT 116 C129(1.37); C140(1.37)  LDD0714  [1]
 LDCM0398  CL127 HCT 116 C129(1.33); C140(1.33)  LDD0715  [1]
 LDCM0399  CL128 HCT 116 C129(2.03); C140(2.03)  LDD0716  [1]
 LDCM0400  CL13 HCT 116 C129(1.06); C140(1.06)  LDD0717  [1]
 LDCM0401  CL14 HCT 116 C129(1.56); C140(1.56)  LDD0718  [1]
 LDCM0402  CL15 HCT 116 C129(0.94); C140(0.94)  LDD0719  [1]
 LDCM0403  CL16 HCT 116 C129(1.60); C140(1.60)  LDD0720  [1]
 LDCM0404  CL17 HCT 116 C129(0.76); C140(0.76)  LDD0721  [1]
 LDCM0405  CL18 HCT 116 C129(1.17); C140(1.17)  LDD0722  [1]
 LDCM0406  CL19 HCT 116 C129(1.22); C140(1.22)  LDD0723  [1]
 LDCM0407  CL2 HCT 116 C129(0.81); C140(0.81)  LDD0724  [1]
 LDCM0408  CL20 HCT 116 C129(1.13); C140(1.13)  LDD0725  [1]
 LDCM0409  CL21 HCT 116 C129(1.26); C140(1.26)  LDD0726  [1]
 LDCM0410  CL22 HCT 116 C129(0.95); C140(0.95)  LDD0727  [1]
 LDCM0411  CL23 HCT 116 C129(1.10); C140(1.10)  LDD0728  [1]
 LDCM0412  CL24 HCT 116 C129(1.63); C140(1.63)  LDD0729  [1]
 LDCM0413  CL25 HCT 116 C129(1.44); C140(1.44)  LDD0730  [1]
 LDCM0414  CL26 HCT 116 C129(1.24); C140(1.24)  LDD0731  [1]
 LDCM0415  CL27 HCT 116 C129(1.48); C140(1.48)  LDD0732  [1]
 LDCM0416  CL28 HCT 116 C129(1.71); C140(1.71)  LDD0733  [1]
 LDCM0417  CL29 HCT 116 C129(1.39); C140(1.39)  LDD0734  [1]
 LDCM0418  CL3 HCT 116 C129(0.92); C140(0.92)  LDD0735  [1]
 LDCM0419  CL30 HCT 116 C129(1.22); C140(1.22)  LDD0736  [1]
 LDCM0420  CL31 HEK-293T C129(0.94); C140(0.94)  LDD1018  [1]
 LDCM0421  CL32 HEK-293T C129(0.71); C140(0.71)  LDD1019  [1]
 LDCM0422  CL33 HEK-293T C129(1.81); C140(1.81)  LDD1020  [1]
 LDCM0423  CL34 HEK-293T C129(0.80); C140(0.80)  LDD1021  [1]
 LDCM0424  CL35 HEK-293T C129(1.09); C140(1.09)  LDD1022  [1]
 LDCM0425  CL36 HEK-293T C129(0.85); C140(0.85)  LDD1023  [1]
 LDCM0426  CL37 HEK-293T C129(0.86); C140(0.86)  LDD1024  [1]
 LDCM0428  CL39 HEK-293T C129(1.32); C140(1.32)  LDD1026  [1]
 LDCM0429  CL4 HCT 116 C129(1.11); C140(1.11)  LDD0746  [1]
 LDCM0430  CL40 HEK-293T C129(0.70); C140(0.70)  LDD1028  [1]
 LDCM0431  CL41 HEK-293T C129(1.09); C140(1.09)  LDD1029  [1]
 LDCM0432  CL42 HEK-293T C129(0.74); C140(0.74)  LDD1030  [1]
 LDCM0433  CL43 HEK-293T C129(0.70); C140(0.70)  LDD1031  [1]
 LDCM0434  CL44 HEK-293T C129(0.97); C140(0.97)  LDD1032  [1]
 LDCM0435  CL45 HEK-293T C129(0.76); C140(0.76)  LDD1033  [1]
 LDCM0436  CL46 HCT 116 C129(1.04); C140(1.04)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C129(0.97); C140(0.97)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C129(0.82); C140(0.82)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C129(0.99); C140(0.99)  LDD0756  [1]
 LDCM0440  CL5 HCT 116 C129(1.01); C140(1.01)  LDD0757  [1]
 LDCM0441  CL50 HCT 116 C129(1.20); C140(1.20)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C129(1.00); C140(1.00)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C129(1.25); C140(1.25)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C129(0.99); C140(0.99)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C129(0.87); C140(0.87)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C129(0.90); C140(0.90)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C129(1.05); C140(1.05)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C129(1.20); C140(1.20)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C129(1.43); C140(1.43)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C129(1.04); C140(1.04)  LDD0767  [1]
 LDCM0451  CL6 HCT 116 C129(1.12); C140(1.12)  LDD0768  [1]
 LDCM0452  CL60 HCT 116 C129(0.92); C140(0.92)  LDD0769  [1]
 LDCM0453  CL61 HEK-293T C129(0.98); C140(0.98)  LDD1051  [1]
 LDCM0454  CL62 HEK-293T C129(1.00); C140(1.00)  LDD1052  [1]
 LDCM0455  CL63 HEK-293T C129(0.93); C140(0.93)  LDD1053  [1]
 LDCM0456  CL64 HEK-293T C129(1.56); C140(1.56)  LDD1054  [1]
 LDCM0457  CL65 HEK-293T C129(0.91); C140(0.91)  LDD1055  [1]
 LDCM0458  CL66 HEK-293T C129(0.91); C140(0.91)  LDD1056  [1]
 LDCM0459  CL67 HEK-293T C129(0.88); C140(0.88)  LDD1057  [1]
 LDCM0460  CL68 HEK-293T C129(0.95); C140(0.95)  LDD1058  [1]
 LDCM0461  CL69 HEK-293T C129(1.42); C140(1.42)  LDD1059  [1]
 LDCM0462  CL7 HCT 116 C129(1.14); C140(1.14)  LDD0779  [1]
 LDCM0463  CL70 HEK-293T C129(1.17); C140(1.17)  LDD1061  [1]
 LDCM0464  CL71 HEK-293T C129(1.27); C140(1.27)  LDD1062  [1]
 LDCM0465  CL72 HEK-293T C129(1.05); C140(1.05)  LDD1063  [1]
 LDCM0466  CL73 HEK-293T C129(1.05); C140(1.05)  LDD1064  [1]
 LDCM0467  CL74 HEK-293T C129(1.01); C140(1.01)  LDD1065  [1]
 LDCM0469  CL76 PaTu 8988t C129(1.02); C140(1.02)  LDD1348  [1]
 LDCM0470  CL77 PaTu 8988t C129(1.54); C140(1.54)  LDD1349  [1]
 LDCM0471  CL78 PaTu 8988t C129(1.58); C140(1.58)  LDD1350  [1]
 LDCM0472  CL79 PaTu 8988t C129(1.30); C140(1.30)  LDD1351  [1]
 LDCM0473  CL8 HCT 116 C129(2.29); C140(2.29)  LDD0790  [1]
 LDCM0474  CL80 PaTu 8988t C129(1.22); C140(1.22)  LDD1353  [1]
 LDCM0475  CL81 PaTu 8988t C129(1.24); C140(1.24)  LDD1354  [1]
 LDCM0476  CL82 PaTu 8988t C129(1.17); C140(1.17)  LDD1355  [1]
 LDCM0477  CL83 PaTu 8988t C129(1.53); C140(1.53)  LDD1356  [1]
 LDCM0478  CL84 PaTu 8988t C129(0.84); C140(0.84)  LDD1357  [1]
 LDCM0479  CL85 PaTu 8988t C129(1.27); C140(1.27)  LDD1358  [1]
 LDCM0480  CL86 PaTu 8988t C129(1.10); C140(1.10)  LDD1359  [1]
 LDCM0481  CL87 PaTu 8988t C129(1.31); C140(1.31)  LDD1360  [1]
 LDCM0482  CL88 PaTu 8988t C129(1.43); C140(1.43)  LDD1361  [1]
 LDCM0483  CL89 PaTu 8988t C129(1.26); C140(1.26)  LDD1362  [1]
 LDCM0484  CL9 HCT 116 C129(1.01); C140(1.01)  LDD0801  [1]
 LDCM0485  CL90 PaTu 8988t C129(1.71); C140(1.71)  LDD1364  [1]
 LDCM0486  CL91 HCT 116 C129(0.98); C140(0.98)  LDD0803  [1]
 LDCM0487  CL92 HCT 116 C129(0.92); C140(0.92)  LDD0804  [1]
 LDCM0488  CL93 HCT 116 C129(1.05); C140(1.05)  LDD0805  [1]
 LDCM0489  CL94 HCT 116 C129(1.16); C140(1.16)  LDD0806  [1]
 LDCM0490  CL95 HCT 116 C129(1.07); C140(1.07)  LDD0807  [1]
 LDCM0491  CL96 HCT 116 C129(1.00); C140(1.00)  LDD0808  [1]
 LDCM0492  CL97 HCT 116 C129(1.14); C140(1.14)  LDD0809  [1]
 LDCM0493  CL98 HCT 116 C129(0.98); C140(0.98)  LDD0810  [1]
 LDCM0494  CL99 HCT 116 C129(1.16); C140(1.16)  LDD0811  [1]
 LDCM0495  E2913 HEK-293T C181(1.12)  LDD1698  [4]
 LDCM0468  Fragment33 HEK-293T C129(1.08); C140(1.08)  LDD1066  [1]
 LDCM0427  Fragment51 HEK-293T C129(0.73); C140(0.73)  LDD1025  [1]
 LDCM0022  KB02 T cell-activated C129(5.82)  LDD1704  [5]
 LDCM0023  KB03 769-P C181(3.07)  LDD2663  [6]
 LDCM0024  KB05 HMCB C181(4.10)  LDD3312  [6]
 LDCM0021  THZ1 HCT 116 C129(1.21); C140(1.21)  LDD2173  [1]

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
4 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
5 An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.
6 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840