Details of the Target

General Information of Target

Target ID LDTP16230
Target Name CCR4-NOT transcription complex subunit 11 (CNOT11)
Gene Name CNOT11
Gene ID 55571
Synonyms
C2orf29; CCR4-NOT transcription complex subunit 11
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MWLPALVLATLAASAAWAGHLSSPPLVDTLHGKVLGKFVSLEGFAQPVAVFLGIPFAKPP
LGPLRFTLPQPAEPWNFVKNATSYPPMFTQDPKAGQLISELFTNRKENIPLKLSEDCLYL
NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS
TGDEHSPGNWGHLDQLAALHWVQDNIASFGGNPGSVTIFGGSVGGESVSVLVLSPLAKNL
FHRAISESGVALTSVLVKKGDVKPLAEVGLRLVRLRLDTPTSLALCS
Target Bioclass
Other
Family
CNOT11 family
Subcellular location
Cytoplasm
Function
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function.
Uniprot ID
Q9UKZ1
Ensemble ID
ENST00000289382.8
HGNC ID
HGNC:25217
ChEMBL ID
CHEMBL4105958

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 7 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K495(1.72)  LDD0277  [1]
IA-alkyne
 Probe Info  		C453(1.23)  LDD2187  [2]
DBIA
 Probe Info  		C453(0.94)  LDD1093  [3]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [4]
IPM
 Probe Info  		C436(0.00); C453(0.00)  LDD2156  [5]
1c-yne
 Probe Info  		N.A.  LDD0228  [6]
AOyne
 Probe Info  		15.00  LDD0443  [7]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 PaTu 8988t C453(0.94)  LDD1093  [3]
 LDCM0215  AC10 PaTu 8988t C453(1.16)  LDD1094  [3]
 LDCM0216  AC100 PaTu 8988t C453(0.93)  LDD1095  [3]
 LDCM0217  AC101 PaTu 8988t C453(0.85)  LDD1096  [3]
 LDCM0218  AC102 PaTu 8988t C453(0.72)  LDD1097  [3]
 LDCM0219  AC103 PaTu 8988t C453(0.88)  LDD1098  [3]
 LDCM0220  AC104 PaTu 8988t C453(1.09)  LDD1099  [3]
 LDCM0221  AC105 PaTu 8988t C453(0.84)  LDD1100  [3]
 LDCM0222  AC106 PaTu 8988t C453(0.92)  LDD1101  [3]
 LDCM0223  AC107 PaTu 8988t C453(1.00)  LDD1102  [3]
 LDCM0224  AC108 PaTu 8988t C453(0.85)  LDD1103  [3]
 LDCM0225  AC109 PaTu 8988t C453(0.96)  LDD1104  [3]
 LDCM0226  AC11 PaTu 8988t C453(1.01)  LDD1105  [3]
 LDCM0227  AC110 PaTu 8988t C453(0.82)  LDD1106  [3]
 LDCM0228  AC111 PaTu 8988t C453(0.68)  LDD1107  [3]
 LDCM0229  AC112 PaTu 8988t C453(0.88)  LDD1108  [3]
 LDCM0230  AC113 PaTu 8988t C453(0.89)  LDD1109  [3]
 LDCM0231  AC114 PaTu 8988t C453(0.85)  LDD1110  [3]
 LDCM0232  AC115 PaTu 8988t C453(1.06)  LDD1111  [3]
 LDCM0233  AC116 PaTu 8988t C453(0.78)  LDD1112  [3]
 LDCM0234  AC117 PaTu 8988t C453(1.31)  LDD1113  [3]
 LDCM0235  AC118 PaTu 8988t C453(1.02)  LDD1114  [3]
 LDCM0236  AC119 PaTu 8988t C453(0.89)  LDD1115  [3]
 LDCM0237  AC12 PaTu 8988t C453(1.00)  LDD1116  [3]
 LDCM0238  AC120 PaTu 8988t C453(1.13)  LDD1117  [3]
 LDCM0239  AC121 PaTu 8988t C453(1.04)  LDD1118  [3]
 LDCM0240  AC122 PaTu 8988t C453(1.02)  LDD1119  [3]
 LDCM0241  AC123 PaTu 8988t C453(1.08)  LDD1120  [3]
 LDCM0242  AC124 PaTu 8988t C453(1.09)  LDD1121  [3]
 LDCM0243  AC125 PaTu 8988t C453(0.84)  LDD1122  [3]
 LDCM0244  AC126 PaTu 8988t C453(0.97)  LDD1123  [3]
 LDCM0245  AC127 PaTu 8988t C453(1.01)  LDD1124  [3]
 LDCM0246  AC128 PaTu 8988t C453(0.96)  LDD1125  [3]
 LDCM0247  AC129 PaTu 8988t C453(0.78)  LDD1126  [3]
 LDCM0249  AC130 PaTu 8988t C453(0.97)  LDD1128  [3]
 LDCM0250  AC131 PaTu 8988t C453(1.32)  LDD1129  [3]
 LDCM0251  AC132 PaTu 8988t C453(0.86)  LDD1130  [3]
 LDCM0252  AC133 PaTu 8988t C453(0.69)  LDD1131  [3]
 LDCM0253  AC134 PaTu 8988t C453(0.90)  LDD1132  [3]
 LDCM0254  AC135 PaTu 8988t C453(1.10)  LDD1133  [3]
 LDCM0255  AC136 PaTu 8988t C453(0.84)  LDD1134  [3]
 LDCM0256  AC137 PaTu 8988t C453(0.75)  LDD1135  [3]
 LDCM0257  AC138 PaTu 8988t C453(0.72)  LDD1136  [3]
 LDCM0258  AC139 PaTu 8988t C453(1.02)  LDD1137  [3]
 LDCM0259  AC14 PaTu 8988t C453(1.07)  LDD1138  [3]
 LDCM0260  AC140 PaTu 8988t C453(0.95)  LDD1139  [3]
 LDCM0261  AC141 PaTu 8988t C453(0.84)  LDD1140  [3]
 LDCM0262  AC142 PaTu 8988t C453(0.84)  LDD1141  [3]
 LDCM0270  AC15 PaTu 8988t C453(1.03)  LDD1149  [3]
 LDCM0276  AC17 PaTu 8988t C453(0.88)  LDD1155  [3]
 LDCM0277  AC18 PaTu 8988t C453(0.85)  LDD1156  [3]
 LDCM0278  AC19 PaTu 8988t C453(1.07)  LDD1157  [3]
 LDCM0279  AC2 PaTu 8988t C453(0.85)  LDD1158  [3]
 LDCM0280  AC20 PaTu 8988t C453(1.35)  LDD1159  [3]
 LDCM0281  AC21 PaTu 8988t C453(1.08)  LDD1160  [3]
 LDCM0282  AC22 PaTu 8988t C453(1.16)  LDD1161  [3]
 LDCM0283  AC23 PaTu 8988t C453(1.02)  LDD1162  [3]
 LDCM0284  AC24 PaTu 8988t C453(1.13)  LDD1163  [3]
 LDCM0285  AC25 HEK-293T C453(0.95); C436(1.11)  LDD1524  [8]
 LDCM0286  AC26 HEK-293T C453(0.98)  LDD1525  [8]
 LDCM0287  AC27 HEK-293T C436(1.03)  LDD1526  [8]
 LDCM0288  AC28 HEK-293T C453(0.86)  LDD1527  [8]
 LDCM0289  AC29 HEK-293T C453(0.93)  LDD1528  [8]
 LDCM0290  AC3 PaTu 8988t C453(0.95)  LDD1169  [3]
 LDCM0291  AC30 HEK-293T C453(0.91)  LDD1530  [8]
 LDCM0292  AC31 HEK-293T C453(0.95); C436(1.00)  LDD1531  [8]
 LDCM0293  AC32 HEK-293T C453(1.09); C436(1.07)  LDD1532  [8]
 LDCM0294  AC33 HEK-293T C453(0.92); C436(1.01)  LDD1533  [8]
 LDCM0295  AC34 HEK-293T C453(0.94)  LDD1534  [8]
 LDCM0296  AC35 PaTu 8988t C453(0.82)  LDD1175  [3]
 LDCM0297  AC36 PaTu 8988t C453(0.85)  LDD1176  [3]
 LDCM0298  AC37 PaTu 8988t C453(0.81)  LDD1177  [3]
 LDCM0299  AC38 PaTu 8988t C453(0.81)  LDD1178  [3]
 LDCM0300  AC39 PaTu 8988t C453(0.91)  LDD1179  [3]
 LDCM0301  AC4 PaTu 8988t C453(0.96)  LDD1180  [3]
 LDCM0302  AC40 PaTu 8988t C453(0.90)  LDD1181  [3]
 LDCM0303  AC41 PaTu 8988t C453(0.81)  LDD1182  [3]
 LDCM0304  AC42 PaTu 8988t C453(0.76)  LDD1183  [3]
 LDCM0305  AC43 PaTu 8988t C453(0.84)  LDD1184  [3]
 LDCM0306  AC44 PaTu 8988t C453(0.84)  LDD1185  [3]
 LDCM0307  AC45 PaTu 8988t C453(0.80)  LDD1186  [3]
 LDCM0308  AC46 PaTu 8988t C453(0.67)  LDD1187  [3]
 LDCM0309  AC47 PaTu 8988t C453(0.77)  LDD1188  [3]
 LDCM0310  AC48 PaTu 8988t C453(0.99)  LDD1189  [3]
 LDCM0311  AC49 PaTu 8988t C453(0.79)  LDD1190  [3]
 LDCM0312  AC5 PaTu 8988t C453(1.13)  LDD1191  [3]
 LDCM0313  AC50 PaTu 8988t C453(1.39)  LDD1192  [3]
 LDCM0314  AC51 PaTu 8988t C453(1.07)  LDD1193  [3]
 LDCM0315  AC52 PaTu 8988t C453(0.87)  LDD1194  [3]
 LDCM0316  AC53 PaTu 8988t C453(0.94)  LDD1195  [3]
 LDCM0317  AC54 PaTu 8988t C453(0.95)  LDD1196  [3]
 LDCM0318  AC55 PaTu 8988t C453(0.94)  LDD1197  [3]
 LDCM0319  AC56 PaTu 8988t C453(1.29)  LDD1198  [3]
 LDCM0320  AC57 PaTu 8988t C453(1.02)  LDD1199  [3]
 LDCM0321  AC58 PaTu 8988t C453(0.83)  LDD1200  [3]
 LDCM0322  AC59 PaTu 8988t C453(0.91)  LDD1201  [3]
 LDCM0323  AC6 PaTu 8988t C453(0.94)  LDD1202  [3]
 LDCM0324  AC60 PaTu 8988t C453(0.93)  LDD1203  [3]
 LDCM0325  AC61 PaTu 8988t C453(1.04)  LDD1204  [3]
 LDCM0326  AC62 PaTu 8988t C453(1.02)  LDD1205  [3]
 LDCM0327  AC63 PaTu 8988t C453(0.80)  LDD1206  [3]
 LDCM0328  AC64 PaTu 8988t C453(0.86)  LDD1207  [3]
 LDCM0329  AC65 PaTu 8988t C453(0.96)  LDD1208  [3]
 LDCM0330  AC66 PaTu 8988t C453(1.03)  LDD1209  [3]
 LDCM0331  AC67 PaTu 8988t C453(0.98)  LDD1210  [3]
 LDCM0334  AC7 PaTu 8988t C453(1.04)  LDD1213  [3]
 LDCM0345  AC8 PaTu 8988t C453(1.05)  LDD1224  [3]
 LDCM0365  AC98 PaTu 8988t C453(0.79)  LDD1244  [3]
 LDCM0366  AC99 PaTu 8988t C453(1.29)  LDD1245  [3]
 LDCM0248  AKOS034007472 PaTu 8988t C453(1.05)  LDD1127  [3]
 LDCM0356  AKOS034007680 PaTu 8988t C453(1.11)  LDD1235  [3]
 LDCM0275  AKOS034007705 PaTu 8988t C453(0.99)  LDD1154  [3]
 LDCM0367  CL1 HEK-293T C453(0.95); C436(0.84)  LDD1571  [8]
 LDCM0368  CL10 HEK-293T C453(1.30)  LDD1572  [8]
 LDCM0369  CL100 PaTu 8988t C453(0.91)  LDD1248  [3]
 LDCM0370  CL101 PaTu 8988t C453(1.03)  LDD1249  [3]
 LDCM0371  CL102 PaTu 8988t C453(0.98)  LDD1250  [3]
 LDCM0372  CL103 PaTu 8988t C453(1.03)  LDD1251  [3]
 LDCM0373  CL104 PaTu 8988t C453(1.02)  LDD1252  [3]
 LDCM0374  CL105 PaTu 8988t C453(1.05)  LDD1253  [3]
 LDCM0375  CL106 PaTu 8988t C453(0.92)  LDD1254  [3]
 LDCM0376  CL107 PaTu 8988t C453(0.72)  LDD1255  [3]
 LDCM0377  CL108 PaTu 8988t C453(0.84)  LDD1256  [3]
 LDCM0378  CL109 PaTu 8988t C453(0.97)  LDD1257  [3]
 LDCM0379  CL11 HEK-293T C453(1.38); C436(1.30)  LDD1583  [8]
 LDCM0380  CL110 PaTu 8988t C453(0.96)  LDD1259  [3]
 LDCM0381  CL111 PaTu 8988t C453(1.20)  LDD1260  [3]
 LDCM0382  CL112 HEK-293T C453(0.81)  LDD1586  [8]
 LDCM0383  CL113 HEK-293T C453(1.03); C436(0.89)  LDD1587  [8]
 LDCM0384  CL114 HEK-293T C453(0.98); C436(1.19)  LDD1588  [8]
 LDCM0385  CL115 HEK-293T C453(1.01)  LDD1589  [8]
 LDCM0386  CL116 HEK-293T C453(0.86)  LDD1590  [8]
 LDCM0387  CL117 PaTu 8988t C453(0.77)  LDD1266  [3]
 LDCM0388  CL118 PaTu 8988t C453(0.77)  LDD1267  [3]
 LDCM0389  CL119 PaTu 8988t C453(0.73)  LDD1268  [3]
 LDCM0390  CL12 HEK-293T C453(1.08); C436(1.20)  LDD1594  [8]
 LDCM0391  CL120 PaTu 8988t C453(0.77)  LDD1270  [3]
 LDCM0392  CL121 PaTu 8988t C453(1.01)  LDD1271  [3]
 LDCM0393  CL122 PaTu 8988t C453(1.10)  LDD1272  [3]
 LDCM0394  CL123 PaTu 8988t C453(1.62)  LDD1273  [3]
 LDCM0395  CL124 PaTu 8988t C453(0.86)  LDD1274  [3]
 LDCM0396  CL125 PaTu 8988t C453(0.99)  LDD1275  [3]
 LDCM0397  CL126 PaTu 8988t C453(0.84)  LDD1276  [3]
 LDCM0398  CL127 PaTu 8988t C453(0.80)  LDD1277  [3]
 LDCM0399  CL128 PaTu 8988t C453(0.97)  LDD1278  [3]
 LDCM0400  CL13 HEK-293T C453(1.12); C436(0.86)  LDD1604  [8]
 LDCM0401  CL14 HEK-293T C453(0.98); C436(1.05)  LDD1605  [8]
 LDCM0402  CL15 HEK-293T C453(1.13)  LDD1606  [8]
 LDCM0403  CL16 HEK-293T C453(0.84)  LDD1607  [8]
 LDCM0404  CL17 HEK-293T C453(1.02); C436(1.23)  LDD1608  [8]
 LDCM0405  CL18 HEK-293T C453(1.01)  LDD1609  [8]
 LDCM0406  CL19 HEK-293T C436(1.12)  LDD1610  [8]
 LDCM0407  CL2 HEK-293T C453(1.00); C436(1.13)  LDD1611  [8]
 LDCM0408  CL20 HEK-293T C453(0.91)  LDD1612  [8]
 LDCM0409  CL21 HEK-293T C453(0.94)  LDD1613  [8]
 LDCM0410  CL22 HEK-293T C453(1.15)  LDD1614  [8]
 LDCM0411  CL23 HEK-293T C453(1.19); C436(1.12)  LDD1615  [8]
 LDCM0412  CL24 HEK-293T C453(1.07); C436(1.23)  LDD1616  [8]
 LDCM0413  CL25 HEK-293T C453(1.13); C436(1.06)  LDD1617  [8]
 LDCM0414  CL26 HEK-293T C453(0.94); C436(0.96)  LDD1618  [8]
 LDCM0415  CL27 HEK-293T C453(0.94)  LDD1619  [8]
 LDCM0416  CL28 HEK-293T C453(0.87)  LDD1620  [8]
 LDCM0417  CL29 HEK-293T C453(1.04); C436(0.97)  LDD1621  [8]
 LDCM0418  CL3 HEK-293T C453(1.10)  LDD1622  [8]
 LDCM0419  CL30 HEK-293T C453(1.00)  LDD1623  [8]
 LDCM0420  CL31 HEK-293T C436(1.13)  LDD1624  [8]
 LDCM0421  CL32 HEK-293T C453(0.90)  LDD1625  [8]
 LDCM0422  CL33 HEK-293T C453(1.07)  LDD1626  [8]
 LDCM0423  CL34 HEK-293T C453(1.31)  LDD1627  [8]
 LDCM0424  CL35 HEK-293T C453(1.25); C436(1.17)  LDD1628  [8]
 LDCM0425  CL36 HEK-293T C453(1.32); C436(1.11)  LDD1629  [8]
 LDCM0426  CL37 HEK-293T C453(1.04); C436(0.88)  LDD1630  [8]
 LDCM0428  CL39 HEK-293T C453(0.98)  LDD1632  [8]
 LDCM0429  CL4 HEK-293T C453(0.93)  LDD1633  [8]
 LDCM0430  CL40 HEK-293T C453(0.93)  LDD1634  [8]
 LDCM0431  CL41 HEK-293T C453(0.98); C436(0.95)  LDD1635  [8]
 LDCM0432  CL42 HEK-293T C453(1.04)  LDD1636  [8]
 LDCM0433  CL43 HEK-293T C436(0.95)  LDD1637  [8]
 LDCM0434  CL44 HEK-293T C453(0.99)  LDD1638  [8]
 LDCM0435  CL45 HEK-293T C453(0.92)  LDD1639  [8]
 LDCM0436  CL46 HEK-293T C453(1.24)  LDD1640  [8]
 LDCM0437  CL47 HEK-293T C453(1.07); C436(1.26)  LDD1641  [8]
 LDCM0438  CL48 HEK-293T C453(1.18); C436(1.19)  LDD1642  [8]
 LDCM0439  CL49 HEK-293T C453(1.15); C436(0.87)  LDD1643  [8]
 LDCM0440  CL5 HEK-293T C453(0.95); C436(0.97)  LDD1644  [8]
 LDCM0441  CL50 HEK-293T C453(1.01); C436(1.15)  LDD1645  [8]
 LDCM0443  CL52 HEK-293T C453(0.84)  LDD1646  [8]
 LDCM0444  CL53 HEK-293T C453(0.99); C436(0.98)  LDD1647  [8]
 LDCM0445  CL54 HEK-293T C453(1.25)  LDD1648  [8]
 LDCM0446  CL55 HEK-293T C436(1.09)  LDD1649  [8]
 LDCM0447  CL56 HEK-293T C453(0.96)  LDD1650  [8]
 LDCM0448  CL57 HEK-293T C453(0.95)  LDD1651  [8]
 LDCM0449  CL58 HEK-293T C453(1.38)  LDD1652  [8]
 LDCM0450  CL59 HEK-293T C453(1.16); C436(1.11)  LDD1653  [8]
 LDCM0451  CL6 HEK-293T C453(1.15)  LDD1654  [8]
 LDCM0452  CL60 HEK-293T C453(1.01); C436(1.05)  LDD1655  [8]
 LDCM0453  CL61 PaTu 8988t C453(1.22)  LDD1332  [3]
 LDCM0454  CL62 PaTu 8988t C453(1.25)  LDD1333  [3]
 LDCM0455  CL63 PaTu 8988t C453(1.19)  LDD1334  [3]
 LDCM0456  CL64 PaTu 8988t C453(1.18)  LDD1335  [3]
 LDCM0457  CL65 PaTu 8988t C453(0.97)  LDD1336  [3]
 LDCM0458  CL66 PaTu 8988t C453(1.11)  LDD1337  [3]
 LDCM0459  CL67 PaTu 8988t C453(1.06)  LDD1338  [3]
 LDCM0460  CL68 PaTu 8988t C453(0.92)  LDD1339  [3]
 LDCM0461  CL69 PaTu 8988t C453(0.87)  LDD1340  [3]
 LDCM0462  CL7 HEK-293T C436(1.11)  LDD1665  [8]
 LDCM0463  CL70 PaTu 8988t C453(0.87)  LDD1342  [3]
 LDCM0464  CL71 PaTu 8988t C453(1.12)  LDD1343  [3]
 LDCM0465  CL72 PaTu 8988t C453(0.94)  LDD1344  [3]
 LDCM0466  CL73 PaTu 8988t C453(1.01)  LDD1345  [3]
 LDCM0467  CL74 PaTu 8988t C453(0.99)  LDD1346  [3]
 LDCM0469  CL76 HEK-293T C453(0.90)  LDD1672  [8]
 LDCM0470  CL77 HEK-293T C453(0.98); C436(1.01)  LDD1673  [8]
 LDCM0471  CL78 HEK-293T C453(1.06)  LDD1674  [8]
 LDCM0472  CL79 HEK-293T C436(1.02)  LDD1675  [8]
 LDCM0473  CL8 HEK-293T C453(1.82)  LDD1676  [8]
 LDCM0474  CL80 HEK-293T C453(0.95)  LDD1677  [8]
 LDCM0475  CL81 HEK-293T C453(1.04)  LDD1678  [8]
 LDCM0476  CL82 HEK-293T C453(1.13)  LDD1679  [8]
 LDCM0477  CL83 HEK-293T C453(1.04); C436(1.01)  LDD1680  [8]
 LDCM0478  CL84 HEK-293T C453(1.22); C436(1.05)  LDD1681  [8]
 LDCM0479  CL85 HEK-293T C453(1.21); C436(0.87)  LDD1682  [8]
 LDCM0480  CL86 HEK-293T C453(1.17); C436(1.28)  LDD1683  [8]
 LDCM0481  CL87 HEK-293T C453(0.95)  LDD1684  [8]
 LDCM0482  CL88 HEK-293T C453(1.02)  LDD1685  [8]
 LDCM0483  CL89 HEK-293T C453(1.16); C436(1.15)  LDD1686  [8]
 LDCM0484  CL9 HEK-293T C453(0.98)  LDD1687  [8]
 LDCM0485  CL90 HEK-293T C453(1.20)  LDD1688  [8]
 LDCM0486  CL91 PaTu 8988t C453(0.84)  LDD1365  [3]
 LDCM0487  CL92 PaTu 8988t C453(0.77)  LDD1366  [3]
 LDCM0488  CL93 PaTu 8988t C453(0.83)  LDD1367  [3]
 LDCM0489  CL94 PaTu 8988t C453(0.89)  LDD1368  [3]
 LDCM0490  CL95 PaTu 8988t C453(0.83)  LDD1369  [3]
 LDCM0491  CL96 PaTu 8988t C453(0.77)  LDD1370  [3]
 LDCM0492  CL97 PaTu 8988t C453(0.93)  LDD1371  [3]
 LDCM0493  CL98 PaTu 8988t C453(0.88)  LDD1372  [3]
 LDCM0494  CL99 PaTu 8988t C453(0.87)  LDD1373  [3]
 LDCM0495  E2913 HEK-293T C453(1.02)  LDD1698  [8]
 LDCM0625  F8 Ramos C453(1.23)  LDD2187  [2]
 LDCM0573  Fragment11 Ramos C453(6.16)  LDD2190  [2]
 LDCM0576  Fragment14 Ramos C453(4.69)  LDD2193  [2]
 LDCM0468  Fragment33 PaTu 8988t C453(0.87)  LDD1347  [3]
 LDCM0427  Fragment51 HEK-293T C453(0.89); C436(0.98)  LDD1631  [8]
 LDCM0022  KB02 HEK-293T C453(0.83)  LDD1492  [8]
 LDCM0023  KB03 HEK-293T C453(0.92)  LDD1497  [8]
 LDCM0024  KB05 HEK-293T C453(0.94)  LDD1502  [8]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein MOX-1 (MEOX1) . P50221
Other
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
CCR4-NOT transcription complex subunit 1 (CNOT1) CNOT1 family A5YKK6
CCR4-NOT transcription complex subunit 10 (CNOT10) CNOT10 family Q9H9A5
Protein FAM193B (FAM193B) FAM193 family Q96PV7
Vasculin-like protein 1 (GPBP1L1) Vasculin family Q9HC44
Cation channel sperm-associated targeting subunit tau (C2CD6) . Q53TS8

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
5 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
6 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
7 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
8 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402