Details of the Target

General Information of Target

Target ID LDTP15024
Target Name Protein FAM72A (FAM72A)
Gene Name FAM72A
Gene ID 729533
Synonyms
UGENE; Protein FAM72A; Latent membrane protein 1-induced protein; LMP1-induced protein; LMPIP
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MNENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVME
HTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEED
EEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQLVDLEVPPLEDTTTFKNYFENER
NMFGKLSQLCISNDFGQEDVLLSLTNGSCEENKDRTILVERDGKFELLNLQDIASQGFLP
PINNANSTENDPQQLLPRSSNSSVSGTKKEDSTAKIHAVTHSSTGEPLAYIAQPPLNRKT
CPSSAVNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEKREKLKREEERR
KIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRQENRDPQQAFRLWLK
KKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQL
RLEAKRSKQLQHHLYMSEAKPFRFTDHYN
Target Bioclass
Other
Family
FAM72 family
Subcellular location
Cytoplasm
Function May play a role in the regulation of cellular reactive oxygen species metabolism. May participate in cell growth regulation.
Uniprot ID
Q5TYM5
Ensemble ID
ENST00000341209.9
HGNC ID
HGNC:24044

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C12(0.88)  LDD0532  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0215  AC10 HCT 116 C12(0.88)  LDD0532  [1]
 LDCM0226  AC11 HCT 116 C12(0.86)  LDD0543  [1]
 LDCM0230  AC113 HCT 116 C12(0.66)  LDD0547  [1]
 LDCM0231  AC114 HCT 116 C12(0.70)  LDD0548  [1]
 LDCM0232  AC115 HCT 116 C12(1.05)  LDD0549  [1]
 LDCM0233  AC116 HCT 116 C12(0.95)  LDD0550  [1]
 LDCM0234  AC117 HCT 116 C12(0.63)  LDD0551  [1]
 LDCM0235  AC118 HCT 116 C12(0.61)  LDD0552  [1]
 LDCM0236  AC119 HCT 116 C12(1.05)  LDD0553  [1]
 LDCM0237  AC12 HCT 116 C12(0.71)  LDD0554  [1]
 LDCM0238  AC120 HCT 116 C12(0.51)  LDD0555  [1]
 LDCM0239  AC121 HCT 116 C12(0.54)  LDD0556  [1]
 LDCM0240  AC122 HCT 116 C12(0.77)  LDD0557  [1]
 LDCM0241  AC123 HCT 116 C12(0.48)  LDD0558  [1]
 LDCM0242  AC124 HCT 116 C12(0.75)  LDD0559  [1]
 LDCM0243  AC125 HCT 116 C12(0.59)  LDD0560  [1]
 LDCM0244  AC126 HCT 116 C12(0.70)  LDD0561  [1]
 LDCM0245  AC127 HCT 116 C12(0.74)  LDD0562  [1]
 LDCM0246  AC128 HEK-293T C12(0.90); C17(0.90); C18(0.90)  LDD0844  [1]
 LDCM0247  AC129 HEK-293T C12(1.07); C17(1.07); C18(1.07)  LDD0845  [1]
 LDCM0249  AC130 HEK-293T C12(1.14); C17(1.14); C18(1.14)  LDD0847  [1]
 LDCM0250  AC131 HEK-293T C12(1.01); C17(1.01); C18(1.01)  LDD0848  [1]
 LDCM0251  AC132 HEK-293T C12(0.94); C17(0.94); C18(0.94)  LDD0849  [1]
 LDCM0252  AC133 HEK-293T C12(1.01); C17(1.01); C18(1.01)  LDD0850  [1]
 LDCM0253  AC134 HEK-293T C12(1.26); C17(1.26); C18(1.26)  LDD0851  [1]
 LDCM0254  AC135 HEK-293T C12(1.13); C17(1.13); C18(1.13)  LDD0852  [1]
 LDCM0255  AC136 HEK-293T C12(1.01); C17(1.01); C18(1.01)  LDD0853  [1]
 LDCM0256  AC137 HEK-293T C12(1.10); C17(1.10); C18(1.10)  LDD0854  [1]
 LDCM0257  AC138 HEK-293T C12(0.92); C17(0.92); C18(0.92)  LDD0855  [1]
 LDCM0258  AC139 HEK-293T C12(1.22); C17(1.22); C18(1.22)  LDD0856  [1]
 LDCM0259  AC14 HCT 116 C12(0.66)  LDD0576  [1]
 LDCM0260  AC140 HEK-293T C12(1.23); C17(1.23); C18(1.23)  LDD0858  [1]
 LDCM0261  AC141 HEK-293T C12(1.07); C17(1.07); C18(1.07)  LDD0859  [1]
 LDCM0262  AC142 HEK-293T C12(0.99); C17(0.99); C18(0.99)  LDD0860  [1]
 LDCM0270  AC15 HCT 116 C12(0.92)  LDD0587  [1]
 LDCM0276  AC17 HEK-293T C12(1.01); C17(1.01); C18(1.01)  LDD0874  [1]
 LDCM0277  AC18 HEK-293T C12(1.19); C17(1.19); C18(1.19)  LDD0875  [1]
 LDCM0278  AC19 HEK-293T C12(1.03); C17(1.03); C18(1.03)  LDD0876  [1]
 LDCM0280  AC20 HEK-293T C12(1.35); C17(1.35); C18(1.35)  LDD0878  [1]
 LDCM0281  AC21 HEK-293T C12(1.13); C17(1.13); C18(1.13)  LDD0879  [1]
 LDCM0282  AC22 HEK-293T C12(1.08); C17(1.08); C18(1.08)  LDD0880  [1]
 LDCM0283  AC23 HEK-293T C12(1.06); C17(1.06); C18(1.06)  LDD0881  [1]
 LDCM0284  AC24 HEK-293T C12(1.22); C17(1.22); C18(1.22)  LDD0882  [1]
 LDCM0296  AC35 HEK-293T C12(1.03); C17(1.03); C18(1.03)  LDD0894  [1]
 LDCM0297  AC36 HEK-293T C12(1.01); C17(1.01); C18(1.01)  LDD0895  [1]
 LDCM0298  AC37 HEK-293T C12(0.81); C17(0.81); C18(0.81)  LDD0896  [1]
 LDCM0299  AC38 HEK-293T C12(1.24); C17(1.24); C18(1.24)  LDD0897  [1]
 LDCM0300  AC39 HEK-293T C12(1.37); C17(1.37); C18(1.37)  LDD0898  [1]
 LDCM0302  AC40 HEK-293T C12(0.97); C17(0.97); C18(0.97)  LDD0900  [1]
 LDCM0303  AC41 HEK-293T C12(1.18); C17(1.18); C18(1.18)  LDD0901  [1]
 LDCM0304  AC42 HEK-293T C12(1.07); C17(1.07); C18(1.07)  LDD0902  [1]
 LDCM0305  AC43 HEK-293T C12(1.21); C17(1.21); C18(1.21)  LDD0903  [1]
 LDCM0306  AC44 HEK-293T C12(1.18); C17(1.18); C18(1.18)  LDD0904  [1]
 LDCM0307  AC45 HEK-293T C12(1.19); C17(1.19); C18(1.19)  LDD0905  [1]
 LDCM0308  AC46 HEK-293T C12(0.88); C17(0.88); C18(0.88)  LDD0906  [1]
 LDCM0309  AC47 HEK-293T C12(1.04); C17(1.04); C18(1.04)  LDD0907  [1]
 LDCM0310  AC48 HEK-293T C12(0.99); C17(0.99); C18(0.99)  LDD0908  [1]
 LDCM0311  AC49 HEK-293T C12(0.94); C17(0.94); C18(0.94)  LDD0909  [1]
 LDCM0313  AC50 HEK-293T C12(0.90); C17(0.90); C18(0.90)  LDD0911  [1]
 LDCM0314  AC51 HEK-293T C12(1.02); C17(1.02); C18(1.02)  LDD0912  [1]
 LDCM0315  AC52 HEK-293T C12(0.96); C17(0.96); C18(0.96)  LDD0913  [1]
 LDCM0316  AC53 HEK-293T C12(0.93); C17(0.93); C18(0.93)  LDD0914  [1]
 LDCM0317  AC54 HEK-293T C12(1.04); C17(1.04); C18(1.04)  LDD0915  [1]
 LDCM0318  AC55 HEK-293T C12(1.00); C17(1.00); C18(1.00)  LDD0916  [1]
 LDCM0319  AC56 HEK-293T C12(1.08); C17(1.08); C18(1.08)  LDD0917  [1]
 LDCM0323  AC6 HCT 116 C12(0.80)  LDD0640  [1]
 LDCM0334  AC7 HCT 116 C12(0.81)  LDD0651  [1]
 LDCM0345  AC8 HCT 116 C12(0.74)  LDD0662  [1]
 LDCM0248  AKOS034007472 HCT 116 C12(0.93)  LDD0565  [1]
 LDCM0356  AKOS034007680 HCT 116 C12(0.88)  LDD0673  [1]
 LDCM0275  AKOS034007705 HCT 116 C12(0.87)  LDD0592  [1]
 LDCM0370  CL101 HCT 116 C12(0.85)  LDD0687  [1]
 LDCM0371  CL102 HCT 116 C12(1.02)  LDD0688  [1]
 LDCM0372  CL103 HCT 116 C12(0.70)  LDD0689  [1]
 LDCM0373  CL104 HCT 116 C12(0.76)  LDD0690  [1]
 LDCM0374  CL105 HEK-293T C12(1.27); C17(1.27); C18(1.27)  LDD0972  [1]
 LDCM0375  CL106 HEK-293T C12(1.29); C17(1.29); C18(1.29)  LDD0973  [1]
 LDCM0376  CL107 HEK-293T C12(1.20); C17(1.20); C18(1.20)  LDD0974  [1]
 LDCM0377  CL108 HEK-293T C12(1.16); C17(1.16); C18(1.16)  LDD0975  [1]
 LDCM0378  CL109 HEK-293T C12(1.41); C17(1.41); C18(1.41)  LDD0976  [1]
 LDCM0380  CL110 HEK-293T C12(1.59); C17(1.59); C18(1.59)  LDD0978  [1]
 LDCM0381  CL111 HEK-293T C12(1.52); C17(1.52); C18(1.52)  LDD0979  [1]
 LDCM0387  CL117 HEK-293T C12(1.13); C17(1.13); C18(1.13)  LDD0985  [1]
 LDCM0388  CL118 HEK-293T C12(1.00); C17(1.00); C18(1.00)  LDD0986  [1]
 LDCM0389  CL119 HEK-293T C12(1.07); C17(1.07); C18(1.07)  LDD0987  [1]
 LDCM0391  CL120 HEK-293T C12(1.02); C17(1.02); C18(1.02)  LDD0989  [1]
 LDCM0392  CL121 HEK-293T C12(1.03); C17(1.03); C18(1.03)  LDD0990  [1]
 LDCM0393  CL122 HEK-293T C12(0.87); C17(0.87); C18(0.87)  LDD0991  [1]
 LDCM0394  CL123 HEK-293T C12(1.25); C17(1.25); C18(1.25)  LDD0992  [1]
 LDCM0395  CL124 HEK-293T C12(1.02); C17(1.02); C18(1.02)  LDD0993  [1]
 LDCM0436  CL46 HCT 116 C12(0.95)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C12(0.99)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C12(0.95)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C12(0.98)  LDD0756  [1]
 LDCM0441  CL50 HCT 116 C12(0.90)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C12(0.91)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C12(1.41)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C12(0.93)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C12(1.04)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C12(0.84)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C12(0.82)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C12(0.91)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C12(1.06)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C12(0.90)  LDD0767  [1]
 LDCM0452  CL60 HCT 116 C12(0.97)  LDD0769  [1]
 LDCM0469  CL76 HCT 116 C12(0.81)  LDD0786  [1]
 LDCM0470  CL77 HCT 116 C12(0.72)  LDD0787  [1]
 LDCM0471  CL78 HCT 116 C12(1.03)  LDD0788  [1]
 LDCM0472  CL79 HCT 116 C12(0.80)  LDD0789  [1]
 LDCM0474  CL80 HCT 116 C12(0.74)  LDD0791  [1]
 LDCM0475  CL81 HCT 116 C12(0.70)  LDD0792  [1]
 LDCM0476  CL82 HCT 116 C12(0.73)  LDD0793  [1]
 LDCM0477  CL83 HCT 116 C12(0.85)  LDD0794  [1]
 LDCM0478  CL84 HCT 116 C12(0.83)  LDD0795  [1]
 LDCM0479  CL85 HCT 116 C12(0.87)  LDD0796  [1]
 LDCM0480  CL86 HCT 116 C12(0.70)  LDD0797  [1]
 LDCM0481  CL87 HCT 116 C12(0.69)  LDD0798  [1]
 LDCM0482  CL88 HCT 116 C12(0.67)  LDD0799  [1]
 LDCM0483  CL89 HCT 116 C12(0.80)  LDD0800  [1]
 LDCM0485  CL90 HCT 116 C12(0.81)  LDD0802  [1]

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.