Details of the Target

General Information of Target

Target ID LDTP14344
Target Name Trafficking protein particle complex subunit 13 (TRAPPC13)
Gene Name TRAPPC13
Gene ID 80006
Synonyms
C5orf44; Trafficking protein particle complex subunit 13
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MERGPVVGAGLGAGARIQALLGCLLKVLLWVASALLYFGSEQAARLLGSPCLRRLYHAWL
AAVVIFGPLLQFHVNPRTIFASHGNFFNIKFVNSAWGWTCTFLGGFVLLVVFLATRRVAV
TARHLSRLVVGAAVWRGAGRAFLLIEDLTGSCFEPLPQGLLLHELPDRRSCLAAGHQWRG
YTVSSHTFLLTFCCLLMAEEAAVFAKYLAHGLPAGAPLRLVFLLNVLLLGLWNFLLLCTV
IYFHQYTHKVVGAAVGTFAWYLTYGSWYHQPWSPGSPGHGLFPRPHSSRKHN
Target Bioclass
Other
Family
TRAPPC13 family
Uniprot ID
A5PLN9
Ensemble ID
ENST00000231526.8
HGNC ID
HGNC:25828

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HCT15 SNV: p.N54S .
OZ SNV: p.E209A .
SW837 SNV: p.L41F .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 10 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
DBIA
 Probe Info  		C32(1.99)  LDD3312  [2]
AHL-Pu-1
 Probe Info  		C233(2.17)  LDD0170  [3]
N1
 Probe Info  		Q295(0.00); Q297(0.00)  LDD0245  [4]
4-Iodoacetamidophenylacetylene
 Probe Info  		C32(0.00); C332(0.00)  LDD0038  [5]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [5]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [5]
NAIA_4
 Probe Info  		N.A.  LDD2226  [6]
TFBX
 Probe Info  		N.A.  LDD0148  [7]
NAIA_5
 Probe Info  		N.A.  LDD2223  [6]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA DM93 C233(2.17)  LDD0170  [3]
 LDCM0214  AC1 HEK-293T C332(1.44)  LDD0812  [8]
 LDCM0215  AC10 HEK-293T C332(0.57)  LDD0813  [8]
 LDCM0226  AC11 HEK-293T C332(0.64)  LDD0824  [8]
 LDCM0237  AC12 HEK-293T C332(0.93)  LDD0835  [8]
 LDCM0259  AC14 HEK-293T C332(1.03)  LDD0857  [8]
 LDCM0263  AC143 HEK-293T C332(1.45)  LDD0861  [8]
 LDCM0264  AC144 HEK-293T C332(1.39)  LDD0862  [8]
 LDCM0265  AC145 HEK-293T C332(1.09)  LDD0863  [8]
 LDCM0266  AC146 HEK-293T C332(1.19)  LDD0864  [8]
 LDCM0267  AC147 HEK-293T C332(1.27)  LDD0865  [8]
 LDCM0268  AC148 HEK-293T C332(2.24)  LDD0866  [8]
 LDCM0269  AC149 HEK-293T C332(1.56)  LDD0867  [8]
 LDCM0270  AC15 HEK-293T C332(0.69)  LDD0868  [8]
 LDCM0271  AC150 HEK-293T C332(1.18)  LDD0869  [8]
 LDCM0272  AC151 HEK-293T C332(1.09)  LDD0870  [8]
 LDCM0273  AC152 HEK-293T C332(0.89)  LDD0871  [8]
 LDCM0274  AC153 HEK-293T C332(1.68)  LDD0872  [8]
 LDCM0621  AC154 HEK-293T C332(2.24)  LDD2162  [8]
 LDCM0622  AC155 HEK-293T C332(1.45)  LDD2163  [8]
 LDCM0623  AC156 HEK-293T C332(2.44)  LDD2164  [8]
 LDCM0624  AC157 HEK-293T C332(1.69)  LDD2165  [8]
 LDCM0276  AC17 HEK-293T C32(1.11); C233(1.06); C254(0.93); C126(0.79)  LDD1515  [9]
 LDCM0277  AC18 HEK-293T C32(1.11); C233(1.12); C407(0.91); C254(1.07)  LDD1516  [9]
 LDCM0278  AC19 HEK-293T C32(1.15); C233(1.09); C407(0.90); C254(1.18)  LDD1517  [9]
 LDCM0279  AC2 HEK-293T C332(1.04)  LDD0877  [8]
 LDCM0280  AC20 HEK-293T C32(1.04); C233(0.97); C407(0.81); C254(1.01)  LDD1519  [9]
 LDCM0281  AC21 HEK-293T C32(1.20); C233(1.16); C407(1.02)  LDD1520  [9]
 LDCM0282  AC22 HEK-293T C32(1.00); C233(1.24); C407(1.10); C254(1.04)  LDD1521  [9]
 LDCM0283  AC23 HEK-293T C32(1.08); C233(1.01); C407(1.04); C254(1.03)  LDD1522  [9]
 LDCM0284  AC24 HEK-293T C32(1.11); C233(1.00); C407(0.99); C254(1.04)  LDD1523  [9]
 LDCM0285  AC25 HEK-293T C32(1.08); C233(1.12); C254(0.91); C126(0.86)  LDD1524  [9]
 LDCM0286  AC26 HEK-293T C32(1.10); C233(0.96); C407(0.92); C254(0.88)  LDD1525  [9]
 LDCM0287  AC27 HEK-293T C32(1.07); C233(0.80); C407(0.85); C254(0.90)  LDD1526  [9]
 LDCM0288  AC28 HEK-293T C32(1.07); C233(0.87); C407(0.91); C254(1.11)  LDD1527  [9]
 LDCM0289  AC29 HEK-293T C32(1.08); C233(1.30); C407(1.05)  LDD1528  [9]
 LDCM0290  AC3 HEK-293T C332(1.25)  LDD0888  [8]
 LDCM0291  AC30 HEK-293T C32(1.08); C233(1.08); C407(1.01); C254(1.06)  LDD1530  [9]
 LDCM0292  AC31 HEK-293T C32(1.11); C233(1.08); C407(0.93); C254(1.10)  LDD1531  [9]
 LDCM0293  AC32 HEK-293T C32(1.12); C233(0.99); C407(1.04); C254(0.96)  LDD1532  [9]
 LDCM0294  AC33 HEK-293T C32(1.14); C233(1.20); C254(0.98); C126(0.88)  LDD1533  [9]
 LDCM0295  AC34 HEK-293T C32(1.06); C233(1.01); C407(0.96); C254(0.91)  LDD1534  [9]
 LDCM0296  AC35 HEK-293T C32(1.03); C233(1.16); C407(0.96); C254(1.01)  LDD1535  [9]
 LDCM0297  AC36 HEK-293T C32(1.09); C233(0.92); C407(0.73); C254(1.08)  LDD1536  [9]
 LDCM0298  AC37 HEK-293T C32(1.13); C233(1.01); C407(1.15)  LDD1537  [9]
 LDCM0299  AC38 HEK-293T C32(1.00); C233(1.17); C407(1.01); C254(1.01)  LDD1538  [9]
 LDCM0300  AC39 HEK-293T C32(1.11); C233(1.16); C407(1.05); C254(1.18)  LDD1539  [9]
 LDCM0301  AC4 HEK-293T C332(1.03)  LDD0899  [8]
 LDCM0302  AC40 HEK-293T C32(1.04); C233(1.02); C407(1.00); C254(0.92)  LDD1541  [9]
 LDCM0303  AC41 HEK-293T C32(1.17); C233(1.16); C254(1.00); C126(0.91)  LDD1542  [9]
 LDCM0304  AC42 HEK-293T C32(1.10); C233(1.11); C407(1.03); C254(0.97)  LDD1543  [9]
 LDCM0305  AC43 HEK-293T C32(1.04); C233(1.01); C407(1.04); C254(0.96)  LDD1544  [9]
 LDCM0306  AC44 HEK-293T C32(1.11); C233(0.81); C407(0.84); C254(0.98)  LDD1545  [9]
 LDCM0307  AC45 HEK-293T C32(0.94); C233(1.35); C407(0.98)  LDD1546  [9]
 LDCM0308  AC46 HEK-293T C332(1.05)  LDD0906  [8]
 LDCM0309  AC47 HEK-293T C332(1.58)  LDD0907  [8]
 LDCM0310  AC48 HEK-293T C332(1.01)  LDD0908  [8]
 LDCM0311  AC49 HEK-293T C332(1.15)  LDD0909  [8]
 LDCM0312  AC5 HEK-293T C332(1.48)  LDD0910  [8]
 LDCM0313  AC50 HEK-293T C332(0.92)  LDD0911  [8]
 LDCM0314  AC51 HEK-293T C332(1.56)  LDD0912  [8]
 LDCM0315  AC52 HEK-293T C332(1.64)  LDD0913  [8]
 LDCM0316  AC53 HEK-293T C332(1.17)  LDD0914  [8]
 LDCM0317  AC54 HEK-293T C332(1.95)  LDD0915  [8]
 LDCM0318  AC55 HEK-293T C332(1.29)  LDD0916  [8]
 LDCM0319  AC56 HEK-293T C332(1.41)  LDD0917  [8]
 LDCM0320  AC57 HEK-293T C332(1.01)  LDD0918  [8]
 LDCM0321  AC58 HEK-293T C332(1.32)  LDD0919  [8]
 LDCM0322  AC59 HEK-293T C332(1.70)  LDD0920  [8]
 LDCM0323  AC6 HEK-293T C332(0.86)  LDD0921  [8]
 LDCM0324  AC60 HEK-293T C332(2.11)  LDD0922  [8]
 LDCM0325  AC61 HEK-293T C332(1.46)  LDD0923  [8]
 LDCM0326  AC62 HEK-293T C332(1.72)  LDD0924  [8]
 LDCM0327  AC63 HEK-293T C332(2.46)  LDD0925  [8]
 LDCM0328  AC64 HEK-293T C332(1.72)  LDD0926  [8]
 LDCM0329  AC65 HEK-293T C332(1.90)  LDD0927  [8]
 LDCM0330  AC66 HEK-293T C332(1.18)  LDD0928  [8]
 LDCM0331  AC67 HEK-293T C332(1.32)  LDD0929  [8]
 LDCM0332  AC68 HEK-293T C332(1.27)  LDD0930  [8]
 LDCM0333  AC69 HEK-293T C332(1.58)  LDD0931  [8]
 LDCM0334  AC7 HEK-293T C332(0.98)  LDD0932  [8]
 LDCM0335  AC70 HEK-293T C332(1.17)  LDD0933  [8]
 LDCM0336  AC71 HEK-293T C332(1.22)  LDD0934  [8]
 LDCM0337  AC72 HEK-293T C332(1.46)  LDD0935  [8]
 LDCM0338  AC73 HEK-293T C332(1.54)  LDD0936  [8]
 LDCM0339  AC74 HEK-293T C332(1.25)  LDD0937  [8]
 LDCM0340  AC75 HEK-293T C332(1.16)  LDD0938  [8]
 LDCM0341  AC76 HEK-293T C332(0.94)  LDD0939  [8]
 LDCM0342  AC77 HEK-293T C332(1.19)  LDD0940  [8]
 LDCM0343  AC78 HEK-293T C332(2.13)  LDD0941  [8]
 LDCM0344  AC79 HEK-293T C332(1.66)  LDD0942  [8]
 LDCM0345  AC8 HEK-293T C332(1.08)  LDD0943  [8]
 LDCM0346  AC80 HEK-293T C332(1.48)  LDD0944  [8]
 LDCM0347  AC81 HEK-293T C332(1.26)  LDD0945  [8]
 LDCM0348  AC82 HEK-293T C332(1.40)  LDD0946  [8]
 LDCM0248  AKOS034007472 HEK-293T C332(0.74)  LDD0846  [8]
 LDCM0356  AKOS034007680 HEK-293T C332(0.70)  LDD0954  [8]
 LDCM0275  AKOS034007705 HEK-293T C332(0.90)  LDD0873  [8]
 LDCM0156  Aniline NCI-H1299 11.89  LDD0403  [1]
 LDCM0632  CL-Sc Hep-G2 C254(1.93)  LDD2227  [6]
 LDCM0367  CL1 HEK-293T C32(1.04); C233(1.18); C407(1.20); C344(0.97)  LDD1571  [9]
 LDCM0368  CL10 HEK-293T C32(0.72); C233(0.97); C407(0.99); C254(1.09)  LDD1572  [9]
 LDCM0369  CL100 HEK-293T C332(1.25)  LDD0967  [8]
 LDCM0370  CL101 HEK-293T C332(1.50)  LDD0968  [8]
 LDCM0371  CL102 HEK-293T C332(1.13)  LDD0969  [8]
 LDCM0372  CL103 HEK-293T C332(0.88)  LDD0970  [8]
 LDCM0373  CL104 HEK-293T C332(0.78)  LDD0971  [8]
 LDCM0374  CL105 HEK-293T C32(1.08); C233(0.85); C407(1.04); C344(0.94)  LDD1578  [9]
 LDCM0375  CL106 HEK-293T C32(1.14); C233(0.91); C407(1.01); C254(1.04)  LDD1579  [9]
 LDCM0376  CL107 HEK-293T C32(0.94); C233(1.12); C407(0.98)  LDD1580  [9]
 LDCM0377  CL108 HEK-293T C32(0.99); C233(1.00); C407(0.91); C126(0.89)  LDD1581  [9]
 LDCM0378  CL109 HEK-293T C32(1.01); C233(1.00); C407(0.78); C344(0.97)  LDD1582  [9]
 LDCM0379  CL11 HEK-293T C32(0.72); C233(0.95); C407(1.24); C254(1.04)  LDD1583  [9]
 LDCM0380  CL110 HEK-293T C32(0.93); C233(0.89); C407(0.85); C254(0.91)  LDD1584  [9]
 LDCM0381  CL111 HEK-293T C32(0.88); C233(1.01); C407(0.88)  LDD1585  [9]
 LDCM0382  CL112 HEK-293T C32(1.03); C233(0.98); C407(1.05); C126(0.80)  LDD1586  [9]
 LDCM0383  CL113 HEK-293T C32(1.43); C233(0.93); C407(1.12); C344(1.01)  LDD1587  [9]
 LDCM0384  CL114 HEK-293T C32(1.11); C233(1.23); C407(0.96); C254(0.86)  LDD1588  [9]
 LDCM0385  CL115 HEK-293T C32(0.96); C233(1.17); C407(0.99)  LDD1589  [9]
 LDCM0386  CL116 HEK-293T C32(1.07); C233(1.06); C407(1.18); C126(0.98)  LDD1590  [9]
 LDCM0387  CL117 HEK-293T C32(1.05); C233(1.02); C407(1.15); C344(1.21)  LDD1591  [9]
 LDCM0388  CL118 HEK-293T C32(1.16); C233(1.01); C407(1.01); C254(1.00)  LDD1592  [9]
 LDCM0389  CL119 HEK-293T C32(0.83); C233(1.26); C407(1.08)  LDD1593  [9]
 LDCM0390  CL12 HEK-293T C32(0.85); C233(0.89); C407(1.17); C254(1.02)  LDD1594  [9]
 LDCM0391  CL120 HEK-293T C32(1.04); C233(0.91); C407(1.06); C126(0.84)  LDD1595  [9]
 LDCM0392  CL121 HEK-293T C332(1.33)  LDD0990  [8]
 LDCM0393  CL122 HEK-293T C332(1.32)  LDD0991  [8]
 LDCM0394  CL123 HEK-293T C332(1.47)  LDD0992  [8]
 LDCM0395  CL124 HEK-293T C332(1.45)  LDD0993  [8]
 LDCM0396  CL125 HEK-293T C332(0.99)  LDD0994  [8]
 LDCM0397  CL126 HEK-293T C332(1.30)  LDD0995  [8]
 LDCM0398  CL127 HEK-293T C332(1.10)  LDD0996  [8]
 LDCM0399  CL128 HEK-293T C332(0.90)  LDD0997  [8]
 LDCM0400  CL13 HEK-293T C32(1.12); C233(1.12); C407(1.06); C344(0.97)  LDD1604  [9]
 LDCM0401  CL14 HEK-293T C32(1.03); C233(1.05); C407(1.09); C254(0.99)  LDD1605  [9]
 LDCM0402  CL15 HEK-293T C32(0.81); C233(0.80); C407(0.88)  LDD1606  [9]
 LDCM0403  CL16 HEK-293T C32(1.01); C233(1.06); C407(1.17); C126(0.95)  LDD1607  [9]
 LDCM0404  CL17 HEK-293T C32(0.80); C233(1.08); C254(0.84); C126(0.76)  LDD1608  [9]
 LDCM0405  CL18 HEK-293T C32(0.94); C233(1.06); C407(1.06); C254(0.98)  LDD1609  [9]
 LDCM0406  CL19 HEK-293T C32(0.72); C233(0.92); C407(1.32); C254(0.92)  LDD1610  [9]
 LDCM0407  CL2 HEK-293T C32(1.17); C233(1.14); C407(0.92); C254(1.00)  LDD1611  [9]
 LDCM0408  CL20 HEK-293T C32(0.82); C233(1.09); C407(0.93); C254(1.06)  LDD1612  [9]
 LDCM0409  CL21 HEK-293T C32(0.77); C233(0.95); C407(1.31)  LDD1613  [9]
 LDCM0410  CL22 HEK-293T C32(0.77); C233(1.08); C407(1.02); C254(1.12)  LDD1614  [9]
 LDCM0411  CL23 HEK-293T C32(0.77); C233(1.00); C407(1.22); C254(1.10)  LDD1615  [9]
 LDCM0412  CL24 HEK-293T C32(0.89); C233(0.95); C407(1.15); C254(0.99)  LDD1616  [9]
 LDCM0413  CL25 HEK-293T C32(1.00); C233(1.09); C407(0.95); C344(0.88)  LDD1617  [9]
 LDCM0414  CL26 HEK-293T C32(1.22); C233(1.06); C407(0.86); C254(1.00)  LDD1618  [9]
 LDCM0415  CL27 HEK-293T C32(0.91); C233(0.95); C407(1.01)  LDD1619  [9]
 LDCM0416  CL28 HEK-293T C32(1.02); C233(1.04); C407(0.96); C126(0.83)  LDD1620  [9]
 LDCM0417  CL29 HEK-293T C32(0.87); C233(1.20); C254(1.05); C126(0.98)  LDD1621  [9]
 LDCM0418  CL3 HEK-293T C32(0.86); C233(0.99); C407(1.18)  LDD1622  [9]
 LDCM0419  CL30 HEK-293T C32(0.94); C233(1.05); C407(1.16); C254(0.98)  LDD1623  [9]
 LDCM0420  CL31 HEK-293T C32(0.81); C233(1.06); C407(0.95); C254(0.85)  LDD1624  [9]
 LDCM0421  CL32 HEK-293T C32(0.81); C233(0.85); C407(0.89); C254(0.97)  LDD1625  [9]
 LDCM0422  CL33 HEK-293T C32(0.71); C233(1.00); C407(0.94)  LDD1626  [9]
 LDCM0423  CL34 HEK-293T C32(0.74); C233(0.77); C407(1.13); C254(1.11)  LDD1627  [9]
 LDCM0424  CL35 HEK-293T C32(0.78); C233(1.02); C407(1.03); C254(1.32)  LDD1628  [9]
 LDCM0425  CL36 HEK-293T C32(0.85); C233(0.88); C407(1.06); C254(1.12)  LDD1629  [9]
 LDCM0426  CL37 HEK-293T C32(0.99); C233(1.02); C407(1.00); C344(0.90)  LDD1630  [9]
 LDCM0428  CL39 HEK-293T C32(0.85); C233(0.97); C407(1.05)  LDD1632  [9]
 LDCM0429  CL4 HEK-293T C32(1.05); C233(1.18); C407(1.08); C126(0.97)  LDD1633  [9]
 LDCM0430  CL40 HEK-293T C32(0.96); C233(1.32); C407(1.06); C126(0.97)  LDD1634  [9]
 LDCM0431  CL41 HEK-293T C32(0.94); C233(1.17); C254(0.93); C126(0.92)  LDD1635  [9]
 LDCM0432  CL42 HEK-293T C32(0.94); C233(0.93); C407(0.99); C254(1.28)  LDD1636  [9]
 LDCM0433  CL43 HEK-293T C32(0.85); C233(0.83); C407(1.07); C254(0.88)  LDD1637  [9]
 LDCM0434  CL44 HEK-293T C32(0.83); C233(0.83); C407(1.02); C254(0.96)  LDD1638  [9]
 LDCM0435  CL45 HEK-293T C32(0.83); C233(1.23); C407(1.01)  LDD1639  [9]
 LDCM0436  CL46 HEK-293T C32(0.83); C233(1.04); C407(1.07); C254(1.17)  LDD1640  [9]
 LDCM0437  CL47 HEK-293T C32(0.81); C233(1.07); C407(1.15); C254(1.16)  LDD1641  [9]
 LDCM0438  CL48 HEK-293T C32(0.78); C233(0.97); C407(1.06); C254(1.12)  LDD1642  [9]
 LDCM0439  CL49 HEK-293T C32(1.04); C233(1.03); C407(1.23); C344(1.15)  LDD1643  [9]
 LDCM0440  CL5 HEK-293T C32(0.97); C233(1.33); C254(0.97); C126(1.04)  LDD1644  [9]
 LDCM0441  CL50 HEK-293T C32(1.07); C233(0.86); C407(0.91); C254(0.95)  LDD1645  [9]
 LDCM0443  CL52 HEK-293T C32(0.98); C233(1.03); C407(1.07); C126(0.94)  LDD1646  [9]
 LDCM0444  CL53 HEK-293T C32(0.86); C233(0.95); C254(0.81); C126(0.90)  LDD1647  [9]
 LDCM0445  CL54 HEK-293T C32(0.92); C233(0.84); C407(0.98); C254(1.07)  LDD1648  [9]
 LDCM0446  CL55 HEK-293T C32(0.83); C233(0.85); C407(0.90); C254(0.98)  LDD1649  [9]
 LDCM0447  CL56 HEK-293T C32(0.87); C233(1.02); C407(0.95); C254(1.09)  LDD1650  [9]
 LDCM0448  CL57 HEK-293T C32(0.85); C233(0.84); C407(1.12)  LDD1651  [9]
 LDCM0449  CL58 HEK-293T C32(0.71); C233(0.93); C407(1.16); C254(1.41)  LDD1652  [9]
 LDCM0450  CL59 HEK-293T C32(0.72); C233(1.00); C407(1.15); C254(1.17)  LDD1653  [9]
 LDCM0451  CL6 HEK-293T C32(0.93); C233(1.02); C407(0.95); C254(0.96)  LDD1654  [9]
 LDCM0452  CL60 HEK-293T C32(0.79); C233(0.99); C407(1.16); C254(0.96)  LDD1655  [9]
 LDCM0453  CL61 HEK-293T C332(1.16)  LDD1051  [8]
 LDCM0454  CL62 HEK-293T C332(0.81)  LDD1052  [8]
 LDCM0455  CL63 HEK-293T C332(0.80)  LDD1053  [8]
 LDCM0456  CL64 HEK-293T C332(0.79)  LDD1054  [8]
 LDCM0457  CL65 HEK-293T C332(0.87)  LDD1055  [8]
 LDCM0458  CL66 HEK-293T C332(0.94)  LDD1056  [8]
 LDCM0459  CL67 HEK-293T C332(0.92)  LDD1057  [8]
 LDCM0460  CL68 HEK-293T C332(0.77)  LDD1058  [8]
 LDCM0461  CL69 HEK-293T C332(0.85)  LDD1059  [8]
 LDCM0462  CL7 HEK-293T C32(0.82); C233(0.92); C407(1.08); C254(0.86)  LDD1665  [9]
 LDCM0463  CL70 HEK-293T C332(0.70)  LDD1061  [8]
 LDCM0464  CL71 HEK-293T C332(0.98)  LDD1062  [8]
 LDCM0465  CL72 HEK-293T C332(1.49)  LDD1063  [8]
 LDCM0466  CL73 HEK-293T C332(0.81)  LDD1064  [8]
 LDCM0467  CL74 HEK-293T C332(1.54)  LDD1065  [8]
 LDCM0469  CL76 HEK-293T C32(1.00); C233(1.17); C407(1.15); C126(0.90)  LDD1672  [9]
 LDCM0470  CL77 HEK-293T C32(1.01); C233(1.01); C254(1.00); C126(0.86)  LDD1673  [9]
 LDCM0471  CL78 HEK-293T C32(0.99); C233(0.95); C407(1.07); C254(1.03)  LDD1674  [9]
 LDCM0472  CL79 HEK-293T C32(0.86); C233(0.84); C407(1.10); C254(1.11)  LDD1675  [9]
 LDCM0473  CL8 HEK-293T C32(0.74); C233(0.70); C407(0.77); C254(0.91)  LDD1676  [9]
 LDCM0474  CL80 HEK-293T C32(0.86); C233(1.04); C407(0.84); C254(1.06)  LDD1677  [9]
 LDCM0475  CL81 HEK-293T C32(0.81); C233(1.16); C407(1.04)  LDD1678  [9]
 LDCM0476  CL82 HEK-293T C32(0.78); C233(1.06); C407(1.01); C254(1.03)  LDD1679  [9]
 LDCM0477  CL83 HEK-293T C32(0.89); C233(0.94); C407(1.22); C254(1.12)  LDD1680  [9]
 LDCM0478  CL84 HEK-293T C32(0.86); C233(1.08); C407(0.95); C254(0.94)  LDD1681  [9]
 LDCM0479  CL85 HEK-293T C32(1.22); C233(0.93); C407(1.09); C344(1.18)  LDD1682  [9]
 LDCM0480  CL86 HEK-293T C32(1.39); C233(0.93); C407(1.06); C254(1.25)  LDD1683  [9]
 LDCM0481  CL87 HEK-293T C32(0.95); C233(1.01); C407(0.84)  LDD1684  [9]
 LDCM0482  CL88 HEK-293T C32(1.21); C233(1.13); C407(1.03); C126(0.90)  LDD1685  [9]
 LDCM0483  CL89 HEK-293T C32(0.85); C233(0.97); C254(1.09); C126(0.89)  LDD1686  [9]
 LDCM0484  CL9 HEK-293T C32(0.84); C233(1.13); C407(1.09)  LDD1687  [9]
 LDCM0485  CL90 HEK-293T C32(0.81); C233(0.19); C407(0.86); C254(0.92)  LDD1688  [9]
 LDCM0486  CL91 HEK-293T C332(0.74)  LDD1084  [8]
 LDCM0487  CL92 HEK-293T C332(0.74)  LDD1085  [8]
 LDCM0488  CL93 HEK-293T C332(1.30)  LDD1086  [8]
 LDCM0489  CL94 HEK-293T C332(0.74)  LDD1087  [8]
 LDCM0490  CL95 HEK-293T C332(1.23)  LDD1088  [8]
 LDCM0491  CL96 HEK-293T C332(1.09)  LDD1089  [8]
 LDCM0492  CL97 HEK-293T C332(1.17)  LDD1090  [8]
 LDCM0493  CL98 HEK-293T C332(0.71)  LDD1091  [8]
 LDCM0494  CL99 HEK-293T C332(0.88)  LDD1092  [8]
 LDCM0495  E2913 HEK-293T C32(0.91); C233(1.10); C407(1.09)  LDD1698  [9]
 LDCM0468  Fragment33 HEK-293T C332(1.34)  LDD1066  [8]
 LDCM0427  Fragment51 HEK-293T C32(1.25); C233(0.89); C407(1.05); C254(1.08)  LDD1631  [9]
 LDCM0022  KB02 A101D C32(2.42)  LDD2250  [2]
 LDCM0023  KB03 A101D C32(3.05)  LDD2667  [2]
 LDCM0024  KB05 HMCB C32(1.99)  LDD3312  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Trafficking protein particle complex subunit 3 (TRAPPC3) TRAPP small subunits family O43617
Trafficking protein particle complex subunit 8 (TRAPPC8) TRS85 family Q9Y2L5

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
3 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
4 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.
5 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
6 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
7 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
8 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
9 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402