Details of the Target

General Information of Target

Target ID LDTP13435
Target Name F-box only protein 9 (FBXO9)
Gene Name FBXO9
Gene ID 26268
Synonyms
FBX9; VCIA1; F-box only protein 9; Cross-immune reaction antigen 1; Renal carcinoma antigen NY-REN-57
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEAGGLPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCLGCTECRHPNW
PNQPDVEPESWREAFKQHYLASKTWTKNALDLESSICFSLFRRRRERRTLSVGPGREFDS
LGSALAMASLYDRIVLFPGVYEEQGEIILKVPVEIVGQGKLGEVALLASIDQHCSTTRLC
NLVFTPAWFSPIMYKTTSGHVQFDNCNFENGHIQVHGPGTCQVKFCTFKNTHIFLHNVPL
CVLENCEFVGSENNSVTVEGHPSADKNWAYKYLLGLIKSSPTFLPTEDSDFLMSLDLESR
DQAWSPKTCDIVIEGSQSPTSPASSSPKPGSKAGSQEAEVGSDGERVAQTPDSSDGGLSP
SGEDEDEDQLMYRLSYQVQGPRPVLGGSFLGPPLPGASIQLPSCLVLNSLQQELQKDKEA
MALANSVQGCLIRKCLFRDGKGGVFVCSHGRAKMEGNIFRNLTYAVRCIHNSKIIMLRND
IYRCRASGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGN
GKGIIRNNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQ
WGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHV
TSNHVSYNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILWETELEKEDDPLRRPIT
IALVESNSINHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANNSISCNR
QSGVKVEAQCKVELRGNGIYDNRGHGIITKGDSTIVIENDIIGNRGSGLQLLPRSDTKVI
KNRIHSFRAYGIAVRGRAKALVQENIIFQGKTSKTIFQQISNNRECIMQNNKFLVFKKKS
DTWRLVNPPARPHLENSLRRPSAAHNGQKVTAMATRITARVEGGYHSNRSVFCTIL
Target Bioclass
Other
Subcellular location
Cytoplasm
Function
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability. Ubiquitinates mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is the activated due to the relief of feedback inhibition by mTORC1. Plays a role in maintaining epithelial cell survival by regulating the turn-over of chromatin modulator PRMT4 through ubiquitination and degradation by the proteasomal pathway. Regulates also PPARgamma stability by facilitating PPARgamma/PPARG ubiquitination and thereby plays a role in adipocyte differentiation.
Uniprot ID
Q9UK97
Ensemble ID
ENST00000244426.10
HGNC ID
HGNC:13588

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C226(1.11)  LDD0532  [1]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [2]
IPM
 Probe Info  		N.A.  LDD2156  [3]
m-APA
 Probe Info  		N.A.  LDD0404  [4]
AOyne
 Probe Info  		15.00  LDD0443  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C226(0.59)  LDD1507  [6]
 LDCM0215  AC10 HCT 116 C226(1.11)  LDD0532  [1]
 LDCM0216  AC100 HEK-293T C226(1.06)  LDD0814  [1]
 LDCM0217  AC101 HEK-293T C226(1.00)  LDD0815  [1]
 LDCM0218  AC102 HEK-293T C226(1.00)  LDD0816  [1]
 LDCM0219  AC103 HEK-293T C226(1.51)  LDD0817  [1]
 LDCM0220  AC104 HEK-293T C226(1.06)  LDD0818  [1]
 LDCM0221  AC105 HEK-293T C226(1.22)  LDD0819  [1]
 LDCM0222  AC106 HEK-293T C226(1.31)  LDD0820  [1]
 LDCM0223  AC107 HEK-293T C226(1.13)  LDD0821  [1]
 LDCM0224  AC108 HEK-293T C226(0.87)  LDD0822  [1]
 LDCM0225  AC109 HEK-293T C226(0.95)  LDD0823  [1]
 LDCM0226  AC11 HCT 116 C226(1.16)  LDD0543  [1]
 LDCM0227  AC110 HEK-293T C226(1.27)  LDD0825  [1]
 LDCM0228  AC111 HEK-293T C226(1.28)  LDD0826  [1]
 LDCM0229  AC112 HEK-293T C226(0.93)  LDD0827  [1]
 LDCM0230  AC113 HEK-293T C226(0.89)  LDD0828  [1]
 LDCM0231  AC114 HEK-293T C226(1.20)  LDD0829  [1]
 LDCM0232  AC115 HEK-293T C226(1.49)  LDD0830  [1]
 LDCM0233  AC116 HEK-293T C226(2.08)  LDD0831  [1]
 LDCM0234  AC117 HEK-293T C226(1.12)  LDD0832  [1]
 LDCM0235  AC118 HEK-293T C226(1.56)  LDD0833  [1]
 LDCM0236  AC119 HEK-293T C226(1.34)  LDD0834  [1]
 LDCM0237  AC12 HCT 116 C226(1.03)  LDD0554  [1]
 LDCM0238  AC120 HEK-293T C226(1.09)  LDD0836  [1]
 LDCM0239  AC121 HEK-293T C226(0.87)  LDD0837  [1]
 LDCM0240  AC122 HEK-293T C226(1.01)  LDD0838  [1]
 LDCM0241  AC123 HEK-293T C226(1.35)  LDD0839  [1]
 LDCM0242  AC124 HEK-293T C226(1.34)  LDD0840  [1]
 LDCM0243  AC125 HEK-293T C226(1.10)  LDD0841  [1]
 LDCM0244  AC126 HEK-293T C226(1.19)  LDD0842  [1]
 LDCM0245  AC127 HEK-293T C226(1.21)  LDD0843  [1]
 LDCM0259  AC14 HCT 116 C226(1.19)  LDD0576  [1]
 LDCM0270  AC15 HCT 116 C226(1.09)  LDD0587  [1]
 LDCM0276  AC17 HEK-293T C226(0.71)  LDD1515  [6]
 LDCM0277  AC18 HEK-293T C226(1.05)  LDD1516  [6]
 LDCM0279  AC2 HEK-293T C226(1.05)  LDD1518  [6]
 LDCM0280  AC20 HEK-293T C68(1.07); C226(0.98)  LDD1519  [6]
 LDCM0281  AC21 HEK-293T C226(0.93)  LDD1520  [6]
 LDCM0282  AC22 HEK-293T C226(1.08)  LDD1521  [6]
 LDCM0283  AC23 HEK-293T C68(1.03); C226(0.68)  LDD1522  [6]
 LDCM0284  AC24 HEK-293T C68(1.02); C226(1.25)  LDD1523  [6]
 LDCM0285  AC25 HCT 116 C226(1.22)  LDD0602  [1]
 LDCM0286  AC26 HCT 116 C226(0.94)  LDD0603  [1]
 LDCM0287  AC27 HCT 116 C226(1.04)  LDD0604  [1]
 LDCM0288  AC28 HCT 116 C226(1.11)  LDD0605  [1]
 LDCM0289  AC29 HCT 116 C226(0.83)  LDD0606  [1]
 LDCM0291  AC30 HCT 116 C226(0.80)  LDD0608  [1]
 LDCM0292  AC31 HCT 116 C226(1.07)  LDD0609  [1]
 LDCM0293  AC32 HCT 116 C226(0.88)  LDD0610  [1]
 LDCM0294  AC33 HCT 116 C226(0.89)  LDD0611  [1]
 LDCM0295  AC34 HCT 116 C226(1.00)  LDD0612  [1]
 LDCM0297  AC36 HEK-293T C68(1.24); C226(0.94)  LDD1536  [6]
 LDCM0298  AC37 HEK-293T C226(1.29)  LDD1537  [6]
 LDCM0299  AC38 HEK-293T C226(1.36)  LDD1538  [6]
 LDCM0300  AC39 HEK-293T C68(1.31); C226(0.68)  LDD1539  [6]
 LDCM0301  AC4 HEK-293T C68(1.14); C226(0.87)  LDD1540  [6]
 LDCM0302  AC40 HEK-293T C68(0.99); C226(1.53)  LDD1541  [6]
 LDCM0303  AC41 HEK-293T C226(0.88)  LDD1542  [6]
 LDCM0304  AC42 HEK-293T C226(0.87)  LDD1543  [6]
 LDCM0306  AC44 HEK-293T C68(1.07); C226(1.02)  LDD1545  [6]
 LDCM0307  AC45 HEK-293T C226(1.07)  LDD1546  [6]
 LDCM0308  AC46 HCT 116 C226(0.86)  LDD0625  [1]
 LDCM0309  AC47 HCT 116 C226(0.88)  LDD0626  [1]
 LDCM0310  AC48 HCT 116 C226(0.98)  LDD0627  [1]
 LDCM0311  AC49 HCT 116 C226(0.92)  LDD0628  [1]
 LDCM0312  AC5 HEK-293T C226(1.11)  LDD1551  [6]
 LDCM0313  AC50 HCT 116 C226(0.83)  LDD0630  [1]
 LDCM0314  AC51 HCT 116 C226(0.92)  LDD0631  [1]
 LDCM0315  AC52 HCT 116 C226(0.94)  LDD0632  [1]
 LDCM0316  AC53 HCT 116 C226(0.93)  LDD0633  [1]
 LDCM0317  AC54 HCT 116 C226(1.04)  LDD0634  [1]
 LDCM0318  AC55 HCT 116 C226(1.00)  LDD0635  [1]
 LDCM0319  AC56 HCT 116 C226(0.88)  LDD0636  [1]
 LDCM0320  AC57 HEK-293T C226(0.90)  LDD0918  [1]
 LDCM0321  AC58 HEK-293T C226(1.00)  LDD0919  [1]
 LDCM0322  AC59 HEK-293T C226(1.07)  LDD0920  [1]
 LDCM0323  AC6 HCT 116 C226(0.92)  LDD0640  [1]
 LDCM0324  AC60 HEK-293T C226(1.02)  LDD0922  [1]
 LDCM0325  AC61 HEK-293T C226(1.07)  LDD0923  [1]
 LDCM0326  AC62 HEK-293T C226(1.02)  LDD0924  [1]
 LDCM0327  AC63 HEK-293T C226(0.91)  LDD0925  [1]
 LDCM0328  AC64 HEK-293T C226(0.85)  LDD0926  [1]
 LDCM0329  AC65 HEK-293T C226(1.04)  LDD0927  [1]
 LDCM0330  AC66 HEK-293T C226(1.13)  LDD0928  [1]
 LDCM0331  AC67 HEK-293T C226(0.88)  LDD0929  [1]
 LDCM0334  AC7 HCT 116 C226(0.96)  LDD0651  [1]
 LDCM0345  AC8 HCT 116 C226(1.05)  LDD0662  [1]
 LDCM0365  AC98 HEK-293T C226(1.20)  LDD0963  [1]
 LDCM0366  AC99 HEK-293T C226(1.19)  LDD0964  [1]
 LDCM0248  AKOS034007472 HCT 116 C226(1.20)  LDD0565  [1]
 LDCM0356  AKOS034007680 HCT 116 C226(1.18)  LDD0673  [1]
 LDCM0275  AKOS034007705 HCT 116 C226(0.87)  LDD0592  [1]
 LDCM0156  Aniline NCI-H1299 N.A.  LDD0404  [4]
 LDCM0367  CL1 HCT 116 C226(0.89)  LDD0684  [1]
 LDCM0368  CL10 HCT 116 C226(0.93)  LDD0685  [1]
 LDCM0370  CL101 HCT 116 C226(1.15)  LDD0687  [1]
 LDCM0371  CL102 HCT 116 C226(1.20)  LDD0688  [1]
 LDCM0372  CL103 HCT 116 C226(1.11)  LDD0689  [1]
 LDCM0373  CL104 HCT 116 C226(1.02)  LDD0690  [1]
 LDCM0376  CL107 HEK-293T C68(1.05)  LDD1580  [6]
 LDCM0379  CL11 HCT 116 C226(1.09)  LDD0696  [1]
 LDCM0381  CL111 HEK-293T C68(1.01)  LDD1585  [6]
 LDCM0382  CL112 HCT 116 C226(1.03)  LDD0699  [1]
 LDCM0383  CL113 HCT 116 C226(0.85)  LDD0700  [1]
 LDCM0384  CL114 HCT 116 C226(0.87)  LDD0701  [1]
 LDCM0385  CL115 HCT 116 C226(1.02)  LDD0702  [1]
 LDCM0386  CL116 HCT 116 C226(0.93)  LDD0703  [1]
 LDCM0389  CL119 HEK-293T C68(0.92)  LDD1593  [6]
 LDCM0390  CL12 HCT 116 C226(0.86)  LDD0707  [1]
 LDCM0392  CL121 HCT 116 C226(0.95)  LDD0709  [1]
 LDCM0393  CL122 HCT 116 C226(0.86)  LDD0710  [1]
 LDCM0394  CL123 HCT 116 C226(0.91)  LDD0711  [1]
 LDCM0395  CL124 HCT 116 C226(0.89)  LDD0712  [1]
 LDCM0396  CL125 HEK-293T C226(0.87)  LDD0994  [1]
 LDCM0397  CL126 HEK-293T C226(1.14)  LDD0995  [1]
 LDCM0398  CL127 HEK-293T C226(1.01)  LDD0996  [1]
 LDCM0399  CL128 HEK-293T C226(0.95)  LDD0997  [1]
 LDCM0400  CL13 HCT 116 C226(1.10)  LDD0717  [1]
 LDCM0401  CL14 HCT 116 C226(0.97)  LDD0718  [1]
 LDCM0402  CL15 HCT 116 C226(1.06)  LDD0719  [1]
 LDCM0403  CL16 HEK-293T C226(1.12)  LDD1001  [1]
 LDCM0404  CL17 HEK-293T C226(1.14)  LDD1002  [1]
 LDCM0405  CL18 HEK-293T C226(1.23)  LDD1003  [1]
 LDCM0406  CL19 HEK-293T C226(1.12)  LDD1004  [1]
 LDCM0407  CL2 HCT 116 C226(0.77)  LDD0724  [1]
 LDCM0408  CL20 HEK-293T C226(1.09)  LDD1006  [1]
 LDCM0409  CL21 HEK-293T C226(1.07)  LDD1007  [1]
 LDCM0410  CL22 HEK-293T C226(1.09)  LDD1008  [1]
 LDCM0411  CL23 HEK-293T C226(0.90)  LDD1009  [1]
 LDCM0412  CL24 HEK-293T C226(0.97)  LDD1010  [1]
 LDCM0413  CL25 HEK-293T C226(1.05)  LDD1011  [1]
 LDCM0414  CL26 HEK-293T C226(0.97)  LDD1012  [1]
 LDCM0415  CL27 HEK-293T C226(1.07)  LDD1013  [1]
 LDCM0416  CL28 HEK-293T C226(0.87)  LDD1014  [1]
 LDCM0417  CL29 HEK-293T C226(1.03)  LDD1015  [1]
 LDCM0418  CL3 HCT 116 C226(0.76)  LDD0735  [1]
 LDCM0419  CL30 HEK-293T C226(1.19)  LDD1017  [1]
 LDCM0420  CL31 HEK-293T C226(1.14)  LDD1018  [1]
 LDCM0421  CL32 HEK-293T C226(0.96)  LDD1019  [1]
 LDCM0422  CL33 HEK-293T C226(0.77)  LDD1020  [1]
 LDCM0423  CL34 HEK-293T C226(0.87)  LDD1021  [1]
 LDCM0424  CL35 HEK-293T C226(0.84)  LDD1022  [1]
 LDCM0425  CL36 HEK-293T C226(0.99)  LDD1023  [1]
 LDCM0426  CL37 HEK-293T C226(1.02)  LDD1024  [1]
 LDCM0428  CL39 HEK-293T C226(0.82)  LDD1026  [1]
 LDCM0429  CL4 HCT 116 C226(0.80)  LDD0746  [1]
 LDCM0430  CL40 HEK-293T C226(1.13)  LDD1028  [1]
 LDCM0431  CL41 HEK-293T C226(0.82)  LDD1029  [1]
 LDCM0432  CL42 HEK-293T C226(0.97)  LDD1030  [1]
 LDCM0433  CL43 HEK-293T C226(0.95)  LDD1031  [1]
 LDCM0434  CL44 HEK-293T C226(0.79)  LDD1032  [1]
 LDCM0435  CL45 HEK-293T C226(1.30)  LDD1033  [1]
 LDCM0436  CL46 HEK-293T C226(1.53)  LDD1640  [6]
 LDCM0437  CL47 HEK-293T C68(1.29); C226(0.63)  LDD1641  [6]
 LDCM0438  CL48 HEK-293T C68(1.14); C226(1.00)  LDD1642  [6]
 LDCM0440  CL5 HCT 116 C226(0.91)  LDD0757  [1]
 LDCM0444  CL53 HEK-293T C226(0.61)  LDD1647  [6]
 LDCM0445  CL54 HEK-293T C226(1.47)  LDD1648  [6]
 LDCM0447  CL56 HEK-293T C68(1.16); C226(1.15)  LDD1650  [6]
 LDCM0448  CL57 HEK-293T C226(1.58)  LDD1651  [6]
 LDCM0449  CL58 HEK-293T C226(1.73)  LDD1652  [6]
 LDCM0450  CL59 HEK-293T C68(1.18); C226(0.88)  LDD1653  [6]
 LDCM0451  CL6 HCT 116 C226(0.79)  LDD0768  [1]
 LDCM0452  CL60 HEK-293T C68(1.25); C226(1.36)  LDD1655  [6]
 LDCM0455  CL63 HEK-293T C68(1.48)  LDD1658  [6]
 LDCM0457  CL65 HEK-293T C226(0.82)  LDD1660  [6]
 LDCM0458  CL66 HEK-293T C226(1.13)  LDD1661  [6]
 LDCM0460  CL68 HEK-293T C68(1.25); C226(1.01)  LDD1663  [6]
 LDCM0461  CL69 HEK-293T C226(1.75)  LDD1664  [6]
 LDCM0462  CL7 HCT 116 C226(1.11)  LDD0779  [1]
 LDCM0463  CL70 HEK-293T C226(1.58)  LDD1666  [6]
 LDCM0464  CL71 HEK-293T C68(1.18); C226(0.69)  LDD1667  [6]
 LDCM0465  CL72 HEK-293T C68(1.13); C226(1.30)  LDD1668  [6]
 LDCM0470  CL77 HEK-293T C226(1.08)  LDD1673  [6]
 LDCM0471  CL78 HEK-293T C226(1.06)  LDD1674  [6]
 LDCM0473  CL8 HCT 116 C226(0.78)  LDD0790  [1]
 LDCM0474  CL80 HEK-293T C68(0.97); C226(0.95)  LDD1677  [6]
 LDCM0475  CL81 HEK-293T C226(1.18)  LDD1678  [6]
 LDCM0476  CL82 HEK-293T C226(1.81)  LDD1679  [6]
 LDCM0477  CL83 HEK-293T C68(1.29); C226(0.71)  LDD1680  [6]
 LDCM0478  CL84 HEK-293T C68(1.03); C226(1.26)  LDD1681  [6]
 LDCM0481  CL87 HEK-293T C68(1.02)  LDD1684  [6]
 LDCM0483  CL89 HEK-293T C226(0.75)  LDD1686  [6]
 LDCM0484  CL9 HCT 116 C226(0.90)  LDD0801  [1]
 LDCM0485  CL90 HEK-293T C226(1.14)  LDD1688  [6]
 LDCM0487  CL92 HEK-293T C68(1.21); C226(1.00)  LDD1690  [6]
 LDCM0488  CL93 HEK-293T C226(0.94)  LDD1691  [6]
 LDCM0489  CL94 HEK-293T C226(1.77)  LDD1692  [6]
 LDCM0490  CL95 HEK-293T C68(1.17); C226(0.82)  LDD1693  [6]
 LDCM0491  CL96 HEK-293T C68(1.26); C226(1.26)  LDD1694  [6]
 LDCM0494  CL99 HEK-293T C68(1.13)  LDD1697  [6]
 LDCM0495  E2913 HEK-293T C68(1.13)  LDD1698  [6]
 LDCM0625  F8 Ramos C68(2.17)  LDD2187  [7]
 LDCM0573  Fragment11 Ramos C68(1.22)  LDD2190  [7]
 LDCM0574  Fragment12 Ramos C68(1.62)  LDD2191  [7]
 LDCM0576  Fragment14 Ramos C68(0.64)  LDD2193  [7]
 LDCM0582  Fragment23 Ramos C68(1.24)  LDD2196  [7]
 LDCM0578  Fragment27 Ramos C68(1.17)  LDD2197  [7]
 LDCM0586  Fragment28 Ramos C68(0.94)  LDD2198  [7]
 LDCM0588  Fragment30 Ramos C68(0.81)  LDD2199  [7]
 LDCM0589  Fragment31 Ramos C68(0.85)  LDD2200  [7]
 LDCM0468  Fragment33 HEK-293T C68(1.03)  LDD1671  [6]
 LDCM0596  Fragment38 Ramos C68(1.18)  LDD2203  [7]
 LDCM0427  Fragment51 HEK-293T C226(1.26)  LDD1025  [1]
 LDCM0610  Fragment52 Ramos C68(0.98)  LDD2204  [7]
 LDCM0614  Fragment56 Ramos C68(7.91)  LDD2205  [7]
 LDCM0569  Fragment7 Ramos C68(0.61)  LDD2186  [7]
 LDCM0022  KB02 HEK-293T C68(0.92)  LDD1492  [6]
 LDCM0023  KB03 HEK-293T C68(0.96)  LDD1497  [6]
 LDCM0024  KB05 MKN45 C226(3.46)  LDD3332  [8]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
S-phase kinase-associated protein 1 (SKP1) SKP1 family P63208
Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Telomere length regulation protein TEL2 homolog (TELO2) TEL2 family Q9Y4R8
TELO2-interacting protein 1 homolog (TTI1) Tti1 family O43156

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
3 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
4 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
5 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
6 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
7 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
8 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840