Details of the Target

General Information of Target

Target ID LDTP11610
Target Name Putative Polycomb group protein ASXL3 (ASXL3)
Gene Name ASXL3
Gene ID 80816
Synonyms
KIAA1713; Putative Polycomb group protein ASXL3; Additional sex combs-like protein 3
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MGGLFSRWRTKPSTVEVLESIDKEIQALEEFREKNQRLQKLWVGRLILYSSVLYLFTCLI
VYLWYLPDEFTARLAMTLPFFAFPLIIWSIRTVIIFFFSKRTERNNEALDDLKSQRKKIL
EEVMEKETYKTAKLILERFDPDSKKAKECEPPSAGAAVTARPGQEIRQRTAAQRNLSPTP
ASPNQGPPPQVPVSPGPPKDSSAPGGPPERTVTPALSSNVLPRHLGSPATSVPGMGLHPP
GPPLARPILPRERGALDRIVEYLVGDGPQNRYALICQQCFSHNGMALKEEFEYIAFRCAY
CFFLNPARKTRPQAPRLPEFSFEKRQVVEGSSSVGPLPSGSVLSSDNQFNEESLEHDVLD
DNTEQTDDKIPATEQTNQVIEKASDSEEPEEKQETENEEASVIETNSTVPGADSIPDPEL
SGESLTAE
Target Bioclass
Other
Family
Asx family
Subcellular location
Nucleus
Function
Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility.
Uniprot ID
Q9C0F0
Ensemble ID
ENST00000269197.12
HGNC ID
HGNC:29357

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
22RV1 Insertion: p.V876SfsTer13 .
COLO679 SNV: p.G894E; p.S1261F .
COLO792 SNV: p.E600K .
COLO800 SNV: p.A1078V .
CORL88 SNV: p.S1221T .
DU145 SNV: p.E520Ter .
HCC44 Deletion: p.P1799RfsTer22 DBIA    Probe Info 
HCT116 Deletion: p.P2037HfsTer43 .
HCT15 SNV: p.Q165Ter .
HT1080 SNV: p.I1279K .
HT115 SNV: p.R356M; p.G1378W .
ICC10 SNV: p.L877I .
IPC298 SNV: p.S2077N .
Ishikawa (Heraklio) 02 ER SNV: p.G1756D .
JVM3 SNV: p.P1586T .
K562 SNV: p.P749S .
KMRC3 SNV: p.E2172Q .
L428 SNV: p.Q228K .
LNCaP clone FGC SNV: p.P405S .
MCC13 SNV: p.P749S; p.Q1819Ter; p.P1943L .
MDST8 SNV: p.E821K .
MELHO SNV: p.G217R .
MEWO SNV: p.L392F; p.G1418E .
MIAPACA2 SNV: p.T11S .
MOLT4 SNV: p.C838F .
NB1 SNV: p.L710S .
NB4 SNV: p.H1646N .
NCIH1793 SNV: p.T574K .
NCIH2172 SNV: p.S1490P; p.P2035H .
NCIH2286 SNV: p.E85Ter; p.M1614I .
NCIH2291 SNV: p.P853T .
OPM2 SNV: p.D555A .
PF382 SNV: p.A56V .
SHP77 SNV: p.T153N .
SKNMC SNV: p.K406E .
SW403 SNV: p.E977Ter .
U937 SNV: p.A316E .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		C1738(1.69)  LDD2229  [1]
Acrolein
 Probe Info  		N.A.  LDD0226  [2]
DBIA
 Probe Info  		C2226(0.95); C2230(0.95); C2234(0.95)  LDD0078  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C2230(1.10)  LDD0812  [3]
 LDCM0215  AC10 HEK-293T C2230(0.83); C2234(0.83)  LDD0813  [3]
 LDCM0216  AC100 PaTu 8988t C2226(1.32); C2234(1.32); C2230(1.32)  LDD1095  [3]
 LDCM0217  AC101 PaTu 8988t C2226(1.15); C2234(1.15); C2230(1.15)  LDD1096  [3]
 LDCM0218  AC102 PaTu 8988t C2226(1.03); C2234(1.03); C2230(1.03)  LDD1097  [3]
 LDCM0219  AC103 PaTu 8988t C2226(1.04); C2234(1.04); C2230(1.04)  LDD1098  [3]
 LDCM0220  AC104 PaTu 8988t C2226(1.14); C2234(1.14); C2230(1.14)  LDD1099  [3]
 LDCM0221  AC105 PaTu 8988t C2226(0.75); C2234(0.75); C2230(0.75)  LDD1100  [3]
 LDCM0222  AC106 PaTu 8988t C2226(0.84); C2234(0.84); C2230(0.84)  LDD1101  [3]
 LDCM0223  AC107 PaTu 8988t C2226(0.79); C2234(0.79); C2230(0.79)  LDD1102  [3]
 LDCM0224  AC108 PaTu 8988t C2226(1.08); C2234(1.08); C2230(1.08)  LDD1103  [3]
 LDCM0225  AC109 PaTu 8988t C2226(1.09); C2234(1.09); C2230(1.09)  LDD1104  [3]
 LDCM0226  AC11 HEK-293T C2230(0.55); C2234(0.55)  LDD0824  [3]
 LDCM0227  AC110 PaTu 8988t C2226(1.00); C2234(1.00); C2230(1.00)  LDD1106  [3]
 LDCM0228  AC111 PaTu 8988t C2226(1.08); C2234(1.08); C2230(1.08)  LDD1107  [3]
 LDCM0229  AC112 PaTu 8988t C2226(1.06); C2234(1.06); C2230(1.06)  LDD1108  [3]
 LDCM0230  AC113 HEK-293T C2234(0.92)  LDD0828  [3]
 LDCM0231  AC114 HEK-293T C2234(0.82)  LDD0829  [3]
 LDCM0232  AC115 HEK-293T C2234(0.90)  LDD0830  [3]
 LDCM0233  AC116 HEK-293T C2234(0.82)  LDD0831  [3]
 LDCM0234  AC117 HEK-293T C2234(0.76)  LDD0832  [3]
 LDCM0235  AC118 HEK-293T C2234(0.88)  LDD0833  [3]
 LDCM0236  AC119 HEK-293T C2234(0.89)  LDD0834  [3]
 LDCM0237  AC12 HEK-293T C2230(0.57); C2234(0.57)  LDD0835  [3]
 LDCM0238  AC120 HEK-293T C2234(0.89)  LDD0836  [3]
 LDCM0239  AC121 HEK-293T C2234(0.90)  LDD0837  [3]
 LDCM0240  AC122 HEK-293T C2234(0.80)  LDD0838  [3]
 LDCM0241  AC123 HEK-293T C2234(0.99)  LDD0839  [3]
 LDCM0242  AC124 HEK-293T C2234(1.04)  LDD0840  [3]
 LDCM0243  AC125 HEK-293T C2234(0.91)  LDD0841  [3]
 LDCM0244  AC126 HEK-293T C2234(0.92)  LDD0842  [3]
 LDCM0245  AC127 HEK-293T C2234(0.92)  LDD0843  [3]
 LDCM0259  AC14 HEK-293T C2230(0.88); C2234(0.88)  LDD0857  [3]
 LDCM0263  AC143 PaTu 8988t C2234(0.85); C2230(0.85)  LDD1142  [3]
 LDCM0264  AC144 PaTu 8988t C2234(0.97); C2230(0.97)  LDD1143  [3]
 LDCM0265  AC145 PaTu 8988t C2234(1.16); C2230(1.16)  LDD1144  [3]
 LDCM0266  AC146 PaTu 8988t C2234(1.68); C2230(1.68)  LDD1145  [3]
 LDCM0267  AC147 PaTu 8988t C2234(0.88); C2230(0.88)  LDD1146  [3]
 LDCM0268  AC148 PaTu 8988t C2234(1.09); C2230(1.09)  LDD1147  [3]
 LDCM0269  AC149 PaTu 8988t C2234(1.09); C2230(1.09)  LDD1148  [3]
 LDCM0270  AC15 HEK-293T C2230(0.63); C2234(0.63)  LDD0868  [3]
 LDCM0271  AC150 PaTu 8988t C2234(1.15); C2230(1.15)  LDD1150  [3]
 LDCM0272  AC151 PaTu 8988t C2234(1.44); C2230(1.44)  LDD1151  [3]
 LDCM0273  AC152 PaTu 8988t C2234(1.05); C2230(1.05)  LDD1152  [3]
 LDCM0274  AC153 PaTu 8988t C2234(1.18); C2230(1.18)  LDD1153  [3]
 LDCM0621  AC154 PaTu 8988t C2234(1.35); C2230(1.35)  LDD2166  [3]
 LDCM0622  AC155 PaTu 8988t C2234(1.27); C2230(1.27)  LDD2167  [3]
 LDCM0623  AC156 PaTu 8988t C2234(1.43); C2230(1.43)  LDD2168  [3]
 LDCM0624  AC157 PaTu 8988t C2234(1.71); C2230(1.71)  LDD2169  [3]
 LDCM0276  AC17 HEK-293T C2230(0.68)  LDD0874  [3]
 LDCM0277  AC18 HEK-293T C2230(0.71)  LDD0875  [3]
 LDCM0278  AC19 HEK-293T C2230(0.75)  LDD0876  [3]
 LDCM0279  AC2 HEK-293T C2230(0.87)  LDD0877  [3]
 LDCM0280  AC20 HEK-293T C2230(0.75)  LDD0878  [3]
 LDCM0281  AC21 HEK-293T C2230(0.83)  LDD0879  [3]
 LDCM0282  AC22 HEK-293T C2230(0.68)  LDD0880  [3]
 LDCM0283  AC23 HEK-293T C2230(0.73)  LDD0881  [3]
 LDCM0284  AC24 HEK-293T C2230(0.78)  LDD0882  [3]
 LDCM0285  AC25 PaTu 8988t C2226(0.62); C2234(0.79); C2230(0.79)  LDD1164  [3]
 LDCM0286  AC26 PaTu 8988t C2226(0.82); C2234(0.90); C2230(0.90)  LDD1165  [3]
 LDCM0287  AC27 PaTu 8988t C2226(0.87); C2234(0.87); C2230(0.87)  LDD1166  [3]
 LDCM0288  AC28 PaTu 8988t C2226(0.83); C2234(0.97); C2230(0.97)  LDD1167  [3]
 LDCM0289  AC29 PaTu 8988t C2226(0.78); C2234(0.93); C2230(0.93)  LDD1168  [3]
 LDCM0290  AC3 HEK-293T C2230(1.12)  LDD0888  [3]
 LDCM0291  AC30 PaTu 8988t C2226(0.73); C2234(0.96); C2230(0.96)  LDD1170  [3]
 LDCM0292  AC31 PaTu 8988t C2226(0.51); C2234(0.72); C2230(0.72)  LDD1171  [3]
 LDCM0293  AC32 PaTu 8988t C2226(0.79); C2234(0.90); C2230(0.90)  LDD1172  [3]
 LDCM0294  AC33 PaTu 8988t C2226(0.68); C2234(0.94); C2230(0.94)  LDD1173  [3]
 LDCM0295  AC34 PaTu 8988t C2226(0.79); C2234(0.85); C2230(0.85)  LDD1174  [3]
 LDCM0296  AC35 PaTu 8988t C2234(1.07); C2230(1.07)  LDD1175  [3]
 LDCM0297  AC36 PaTu 8988t C2234(0.87); C2230(0.87)  LDD1176  [3]
 LDCM0298  AC37 PaTu 8988t C2234(1.14); C2230(1.14)  LDD1177  [3]
 LDCM0299  AC38 PaTu 8988t C2234(0.95); C2230(0.95)  LDD1178  [3]
 LDCM0300  AC39 PaTu 8988t C2234(0.99); C2230(0.99)  LDD1179  [3]
 LDCM0301  AC4 HEK-293T C2230(0.85)  LDD0899  [3]
 LDCM0302  AC40 PaTu 8988t C2234(1.07); C2230(1.07)  LDD1181  [3]
 LDCM0303  AC41 PaTu 8988t C2234(0.90); C2230(0.90)  LDD1182  [3]
 LDCM0304  AC42 PaTu 8988t C2234(1.16); C2230(1.16)  LDD1183  [3]
 LDCM0305  AC43 PaTu 8988t C2234(0.85); C2230(0.85)  LDD1184  [3]
 LDCM0306  AC44 PaTu 8988t C2234(1.26); C2230(1.26)  LDD1185  [3]
 LDCM0307  AC45 PaTu 8988t C2234(1.10); C2230(1.10)  LDD1186  [3]
 LDCM0308  AC46 PaTu 8988t C2226(0.93); C2230(0.93)  LDD1187  [3]
 LDCM0309  AC47 PaTu 8988t C2226(1.08); C2230(1.08)  LDD1188  [3]
 LDCM0310  AC48 PaTu 8988t C2226(1.07); C2230(1.07)  LDD1189  [3]
 LDCM0311  AC49 PaTu 8988t C2226(0.96); C2230(0.96)  LDD1190  [3]
 LDCM0312  AC5 HEK-293T C2230(0.95)  LDD0910  [3]
 LDCM0313  AC50 PaTu 8988t C2226(0.97); C2230(0.97)  LDD1192  [3]
 LDCM0314  AC51 PaTu 8988t C2226(0.93); C2230(0.93)  LDD1193  [3]
 LDCM0315  AC52 PaTu 8988t C2226(1.10); C2230(1.10)  LDD1194  [3]
 LDCM0316  AC53 PaTu 8988t C2226(1.21); C2230(1.21)  LDD1195  [3]
 LDCM0317  AC54 PaTu 8988t C2226(1.31); C2230(1.31)  LDD1196  [3]
 LDCM0318  AC55 PaTu 8988t C2226(1.04); C2230(1.04)  LDD1197  [3]
 LDCM0319  AC56 PaTu 8988t C2226(1.45); C2230(1.45)  LDD1198  [3]
 LDCM0320  AC57 PaTu 8988t C2234(0.99); C2230(0.99)  LDD1199  [3]
 LDCM0321  AC58 PaTu 8988t C2234(1.00); C2230(1.00)  LDD1200  [3]
 LDCM0322  AC59 PaTu 8988t C2234(0.87); C2230(0.87)  LDD1201  [3]
 LDCM0323  AC6 HEK-293T C2230(0.72); C2234(0.72)  LDD0921  [3]
 LDCM0324  AC60 PaTu 8988t C2234(1.13); C2230(1.13)  LDD1203  [3]
 LDCM0325  AC61 PaTu 8988t C2234(1.06); C2230(1.06)  LDD1204  [3]
 LDCM0326  AC62 PaTu 8988t C2234(0.98); C2230(0.98)  LDD1205  [3]
 LDCM0327  AC63 PaTu 8988t C2234(1.28); C2230(1.28)  LDD1206  [3]
 LDCM0328  AC64 PaTu 8988t C2234(1.01); C2230(1.01)  LDD1207  [3]
 LDCM0329  AC65 PaTu 8988t C2234(0.98); C2230(0.98)  LDD1208  [3]
 LDCM0330  AC66 PaTu 8988t C2234(0.99); C2230(0.99)  LDD1209  [3]
 LDCM0331  AC67 PaTu 8988t C2234(0.99); C2230(0.99)  LDD1210  [3]
 LDCM0332  AC68 HEK-293T C2230(1.07); C2234(1.03)  LDD0930  [3]
 LDCM0333  AC69 HEK-293T C2230(1.22); C2234(0.96)  LDD0931  [3]
 LDCM0334  AC7 HEK-293T C2230(0.82); C2234(0.82)  LDD0932  [3]
 LDCM0335  AC70 HEK-293T C2230(1.20); C2234(1.00)  LDD0933  [3]
 LDCM0336  AC71 HEK-293T C2230(0.95); C2234(0.96)  LDD0934  [3]
 LDCM0337  AC72 HEK-293T C2230(0.96); C2234(0.94)  LDD0935  [3]
 LDCM0338  AC73 HEK-293T C2230(1.49); C2234(1.23)  LDD0936  [3]
 LDCM0339  AC74 HEK-293T C2230(1.00); C2234(0.84)  LDD0937  [3]
 LDCM0340  AC75 HEK-293T C2230(1.10); C2234(1.08)  LDD0938  [3]
 LDCM0341  AC76 HEK-293T C2230(1.30); C2234(1.06)  LDD0939  [3]
 LDCM0342  AC77 HEK-293T C2230(1.15); C2234(1.17)  LDD0940  [3]
 LDCM0343  AC78 HEK-293T C2230(0.90); C2234(0.83)  LDD0941  [3]
 LDCM0344  AC79 HEK-293T C2230(0.96); C2234(0.98)  LDD0942  [3]
 LDCM0345  AC8 HEK-293T C2230(0.83); C2234(0.83)  LDD0943  [3]
 LDCM0346  AC80 HEK-293T C2230(0.89); C2234(0.83)  LDD0944  [3]
 LDCM0347  AC81 HEK-293T C2230(0.97); C2234(0.79)  LDD0945  [3]
 LDCM0348  AC82 HEK-293T C2230(1.07); C2234(1.22)  LDD0946  [3]
 LDCM0349  AC83 HEK-293T C2230(1.00)  LDD0947  [3]
 LDCM0350  AC84 HEK-293T C2230(0.64)  LDD0948  [3]
 LDCM0351  AC85 HEK-293T C2230(0.62)  LDD0949  [3]
 LDCM0352  AC86 HEK-293T C2230(0.80)  LDD0950  [3]
 LDCM0353  AC87 HEK-293T C2230(0.64)  LDD0951  [3]
 LDCM0354  AC88 HEK-293T C2230(0.93)  LDD0952  [3]
 LDCM0355  AC89 HEK-293T C2230(0.78)  LDD0953  [3]
 LDCM0357  AC90 HEK-293T C2230(0.62)  LDD0955  [3]
 LDCM0358  AC91 HEK-293T C2230(0.62)  LDD0956  [3]
 LDCM0359  AC92 HEK-293T C2230(0.82)  LDD0957  [3]
 LDCM0360  AC93 HEK-293T C2230(0.95)  LDD0958  [3]
 LDCM0361  AC94 HEK-293T C2230(1.31)  LDD0959  [3]
 LDCM0362  AC95 HEK-293T C2230(0.85)  LDD0960  [3]
 LDCM0363  AC96 HEK-293T C2230(0.61)  LDD0961  [3]
 LDCM0364  AC97 HEK-293T C2230(0.70)  LDD0962  [3]
 LDCM0365  AC98 PaTu 8988t C2226(1.24); C2234(1.24); C2230(1.24)  LDD1244  [3]
 LDCM0366  AC99 PaTu 8988t C2226(0.93); C2234(0.93); C2230(0.93)  LDD1245  [3]
 LDCM0248  AKOS034007472 HEK-293T C2230(0.74); C2234(0.74)  LDD0846  [3]
 LDCM0356  AKOS034007680 HEK-293T C2230(0.67); C2234(0.67)  LDD0954  [3]
 LDCM0275  AKOS034007705 HEK-293T C2230(0.87); C2234(0.87)  LDD0873  [3]
 LDCM0020  ARS-1620 HCC44 C2226(0.95); C2230(0.95); C2234(0.95)  LDD0078  [3]
 LDCM0367  CL1 HEK-293T C2230(0.65)  LDD0965  [3]
 LDCM0368  CL10 HEK-293T C2230(0.77)  LDD0966  [3]
 LDCM0369  CL100 HEK-293T C2230(1.16)  LDD0967  [3]
 LDCM0370  CL101 HEK-293T C2230(0.86); C2234(0.86)  LDD0968  [3]
 LDCM0371  CL102 HEK-293T C2230(0.70); C2234(0.70)  LDD0969  [3]
 LDCM0372  CL103 HEK-293T C2230(0.95); C2234(0.95)  LDD0970  [3]
 LDCM0373  CL104 HEK-293T C2230(0.76); C2234(0.76)  LDD0971  [3]
 LDCM0374  CL105 HEK-293T C2230(0.83)  LDD0972  [3]
 LDCM0375  CL106 HEK-293T C2230(0.87)  LDD0973  [3]
 LDCM0376  CL107 HEK-293T C2230(0.91)  LDD0974  [3]
 LDCM0377  CL108 HEK-293T C2230(0.75)  LDD0975  [3]
 LDCM0378  CL109 HEK-293T C2230(0.76)  LDD0976  [3]
 LDCM0379  CL11 HEK-293T C2230(0.72)  LDD0977  [3]
 LDCM0380  CL110 HEK-293T C2230(0.78)  LDD0978  [3]
 LDCM0381  CL111 HEK-293T C2230(0.74)  LDD0979  [3]
 LDCM0382  CL112 PaTu 8988t C2226(0.81); C2234(0.93); C2230(0.93)  LDD1261  [3]
 LDCM0383  CL113 PaTu 8988t C2226(0.72); C2234(0.89); C2230(0.89)  LDD1262  [3]
 LDCM0384  CL114 PaTu 8988t C2226(0.83); C2234(0.89); C2230(0.89)  LDD1263  [3]
 LDCM0385  CL115 PaTu 8988t C2226(0.49); C2234(0.70); C2230(0.70)  LDD1264  [3]
 LDCM0386  CL116 PaTu 8988t C2226(0.92); C2234(1.11); C2230(1.11)  LDD1265  [3]
 LDCM0387  CL117 PaTu 8988t C2234(0.99); C2230(0.99)  LDD1266  [3]
 LDCM0388  CL118 PaTu 8988t C2234(1.51); C2230(1.51)  LDD1267  [3]
 LDCM0389  CL119 PaTu 8988t C2234(1.12); C2230(1.12)  LDD1268  [3]
 LDCM0390  CL12 HEK-293T C2230(0.80)  LDD0988  [3]
 LDCM0391  CL120 PaTu 8988t C2234(0.92); C2230(0.92)  LDD1270  [3]
 LDCM0392  CL121 PaTu 8988t C2226(0.92); C2230(0.92)  LDD1271  [3]
 LDCM0393  CL122 PaTu 8988t C2226(1.47); C2230(1.47)  LDD1272  [3]
 LDCM0394  CL123 PaTu 8988t C2226(1.30); C2230(1.30)  LDD1273  [3]
 LDCM0395  CL124 PaTu 8988t C2226(1.02); C2230(1.02)  LDD1274  [3]
 LDCM0396  CL125 PaTu 8988t C2234(0.98); C2230(0.98)  LDD1275  [3]
 LDCM0397  CL126 PaTu 8988t C2234(0.92); C2230(0.92)  LDD1276  [3]
 LDCM0398  CL127 PaTu 8988t C2234(1.25); C2230(1.25)  LDD1277  [3]
 LDCM0399  CL128 PaTu 8988t C2234(1.04); C2230(1.04)  LDD1278  [3]
 LDCM0400  CL13 HEK-293T C2230(0.66)  LDD0998  [3]
 LDCM0401  CL14 HEK-293T C2230(0.77)  LDD0999  [3]
 LDCM0402  CL15 HEK-293T C2230(0.72)  LDD1000  [3]
 LDCM0403  CL16 HEK-293T C2234(1.15)  LDD1001  [3]
 LDCM0404  CL17 HEK-293T C2234(0.92)  LDD1002  [3]
 LDCM0405  CL18 HEK-293T C2234(0.94)  LDD1003  [3]
 LDCM0406  CL19 HEK-293T C2234(1.15)  LDD1004  [3]
 LDCM0407  CL2 HEK-293T C2230(0.67)  LDD1005  [3]
 LDCM0408  CL20 HEK-293T C2234(0.91)  LDD1006  [3]
 LDCM0409  CL21 HEK-293T C2234(0.84)  LDD1007  [3]
 LDCM0410  CL22 HEK-293T C2234(1.26)  LDD1008  [3]
 LDCM0411  CL23 HEK-293T C2234(1.12)  LDD1009  [3]
 LDCM0412  CL24 HEK-293T C2234(1.12)  LDD1010  [3]
 LDCM0413  CL25 HEK-293T C2234(0.87)  LDD1011  [3]
 LDCM0414  CL26 HEK-293T C2234(1.11)  LDD1012  [3]
 LDCM0415  CL27 HEK-293T C2234(1.33)  LDD1013  [3]
 LDCM0416  CL28 HEK-293T C2234(1.15)  LDD1014  [3]
 LDCM0417  CL29 HEK-293T C2234(1.28)  LDD1015  [3]
 LDCM0418  CL3 HEK-293T C2230(0.64)  LDD1016  [3]
 LDCM0419  CL30 HEK-293T C2234(0.88)  LDD1017  [3]
 LDCM0420  CL31 PaTu 8988t C2230(0.98)  LDD1299  [3]
 LDCM0421  CL32 PaTu 8988t C2230(1.55)  LDD1300  [3]
 LDCM0422  CL33 PaTu 8988t C2230(1.16)  LDD1301  [3]
 LDCM0423  CL34 PaTu 8988t C2230(1.37)  LDD1302  [3]
 LDCM0424  CL35 PaTu 8988t C2230(1.71)  LDD1303  [3]
 LDCM0425  CL36 PaTu 8988t C2230(2.05)  LDD1304  [3]
 LDCM0426  CL37 PaTu 8988t C2230(1.43)  LDD1305  [3]
 LDCM0428  CL39 PaTu 8988t C2230(1.62)  LDD1307  [3]
 LDCM0429  CL4 HEK-293T C2230(0.74)  LDD1027  [3]
 LDCM0430  CL40 PaTu 8988t C2230(1.28)  LDD1309  [3]
 LDCM0431  CL41 PaTu 8988t C2230(1.45)  LDD1310  [3]
 LDCM0432  CL42 PaTu 8988t C2230(1.60)  LDD1311  [3]
 LDCM0433  CL43 PaTu 8988t C2230(2.46)  LDD1312  [3]
 LDCM0434  CL44 PaTu 8988t C2230(1.34)  LDD1313  [3]
 LDCM0435  CL45 PaTu 8988t C2230(1.92)  LDD1314  [3]
 LDCM0436  CL46 PaTu 8988t C2234(1.25); C2230(1.25)  LDD1315  [3]
 LDCM0437  CL47 PaTu 8988t C2234(0.88); C2230(0.88)  LDD1316  [3]
 LDCM0438  CL48 PaTu 8988t C2234(0.98); C2230(0.98)  LDD1317  [3]
 LDCM0439  CL49 PaTu 8988t C2234(1.26); C2230(1.26)  LDD1318  [3]
 LDCM0440  CL5 HEK-293T C2230(0.63)  LDD1038  [3]
 LDCM0441  CL50 PaTu 8988t C2234(1.07); C2230(1.07)  LDD1320  [3]
 LDCM0442  CL51 PaTu 8988t C2234(1.11); C2230(1.11)  LDD1321  [3]
 LDCM0443  CL52 PaTu 8988t C2234(1.15); C2230(1.15)  LDD1322  [3]
 LDCM0444  CL53 PaTu 8988t C2234(1.28); C2230(1.28)  LDD1323  [3]
 LDCM0445  CL54 PaTu 8988t C2234(1.04); C2230(1.04)  LDD1324  [3]
 LDCM0446  CL55 PaTu 8988t C2234(1.08); C2230(1.08)  LDD1325  [3]
 LDCM0447  CL56 PaTu 8988t C2234(0.99); C2230(0.99)  LDD1326  [3]
 LDCM0448  CL57 PaTu 8988t C2234(1.09); C2230(1.09)  LDD1327  [3]
 LDCM0449  CL58 PaTu 8988t C2234(1.16); C2230(1.16)  LDD1328  [3]
 LDCM0450  CL59 PaTu 8988t C2234(1.02); C2230(1.02)  LDD1329  [3]
 LDCM0451  CL6 HEK-293T C2230(0.70)  LDD1049  [3]
 LDCM0452  CL60 PaTu 8988t C2234(0.94); C2230(0.94)  LDD1331  [3]
 LDCM0453  CL61 PaTu 8988t C2226(0.96); C2234(1.02); C2230(1.02)  LDD1332  [3]
 LDCM0454  CL62 PaTu 8988t C2226(1.10); C2234(1.14); C2230(1.14)  LDD1333  [3]
 LDCM0455  CL63 PaTu 8988t C2226(1.21); C2234(1.20); C2230(1.20)  LDD1334  [3]
 LDCM0456  CL64 PaTu 8988t C2226(1.29); C2234(1.30); C2230(1.30)  LDD1335  [3]
 LDCM0457  CL65 PaTu 8988t C2226(0.93); C2234(1.00); C2230(1.00)  LDD1336  [3]
 LDCM0458  CL66 PaTu 8988t C2226(0.93); C2234(1.07); C2230(1.07)  LDD1337  [3]
 LDCM0459  CL67 PaTu 8988t C2226(1.20); C2234(1.28); C2230(1.28)  LDD1338  [3]
 LDCM0460  CL68 PaTu 8988t C2226(2.00); C2234(1.88); C2230(1.88)  LDD1339  [3]
 LDCM0461  CL69 PaTu 8988t C2226(1.47); C2234(1.42); C2230(1.42)  LDD1340  [3]
 LDCM0462  CL7 HEK-293T C2230(0.63)  LDD1060  [3]
 LDCM0463  CL70 PaTu 8988t C2226(1.28); C2234(1.24); C2230(1.24)  LDD1342  [3]
 LDCM0464  CL71 PaTu 8988t C2226(1.28); C2234(1.30); C2230(1.30)  LDD1343  [3]
 LDCM0465  CL72 PaTu 8988t C2226(0.98); C2234(0.98); C2230(0.98)  LDD1344  [3]
 LDCM0466  CL73 PaTu 8988t C2226(1.47); C2234(1.56); C2230(1.56)  LDD1345  [3]
 LDCM0467  CL74 PaTu 8988t C2226(1.20); C2234(1.18); C2230(1.18)  LDD1346  [3]
 LDCM0469  CL76 PaTu 8988t C2226(0.87); C2234(0.83); C2230(0.92)  LDD1348  [3]
 LDCM0470  CL77 PaTu 8988t C2226(0.96); C2234(0.76); C2230(1.17)  LDD1349  [3]
 LDCM0471  CL78 PaTu 8988t C2226(0.92); C2234(0.72); C2230(1.12)  LDD1350  [3]
 LDCM0472  CL79 PaTu 8988t C2226(1.08); C2234(0.92); C2230(1.24)  LDD1351  [3]
 LDCM0473  CL8 HEK-293T C2230(0.88)  LDD1071  [3]
 LDCM0474  CL80 PaTu 8988t C2226(1.01); C2234(0.95); C2230(1.08)  LDD1353  [3]
 LDCM0475  CL81 PaTu 8988t C2226(0.99); C2234(1.08); C2230(0.89)  LDD1354  [3]
 LDCM0476  CL82 PaTu 8988t C2226(0.91); C2234(0.79); C2230(1.02)  LDD1355  [3]
 LDCM0477  CL83 PaTu 8988t C2226(1.07); C2234(0.91); C2230(1.24)  LDD1356  [3]
 LDCM0478  CL84 PaTu 8988t C2226(0.99); C2234(0.90); C2230(1.09)  LDD1357  [3]
 LDCM0479  CL85 PaTu 8988t C2226(0.96); C2234(0.79); C2230(1.13)  LDD1358  [3]
 LDCM0480  CL86 PaTu 8988t C2226(1.05); C2234(0.96); C2230(1.14)  LDD1359  [3]
 LDCM0481  CL87 PaTu 8988t C2226(1.08); C2234(1.15); C2230(1.01)  LDD1360  [3]
 LDCM0482  CL88 PaTu 8988t C2226(1.17); C2234(0.73); C2230(1.60)  LDD1361  [3]
 LDCM0483  CL89 PaTu 8988t C2226(0.96); C2234(0.88); C2230(1.03)  LDD1362  [3]
 LDCM0484  CL9 HEK-293T C2230(1.06)  LDD1082  [3]
 LDCM0485  CL90 PaTu 8988t C2226(0.99); C2234(0.92); C2230(1.07)  LDD1364  [3]
 LDCM0486  CL91 HEK-293T C2230(0.83)  LDD1084  [3]
 LDCM0487  CL92 HEK-293T C2230(1.25)  LDD1085  [3]
 LDCM0488  CL93 HEK-293T C2230(0.78)  LDD1086  [3]
 LDCM0489  CL94 HEK-293T C2230(0.79)  LDD1087  [3]
 LDCM0490  CL95 HEK-293T C2230(0.94)  LDD1088  [3]
 LDCM0491  CL96 HEK-293T C2230(0.99)  LDD1089  [3]
 LDCM0492  CL97 HEK-293T C2230(0.76)  LDD1090  [3]
 LDCM0493  CL98 HEK-293T C2230(0.77)  LDD1091  [3]
 LDCM0494  CL99 HEK-293T C2230(0.94)  LDD1092  [3]
 LDCM0468  Fragment33 PaTu 8988t C2226(1.20); C2234(1.31); C2230(1.31)  LDD1347  [3]
 LDCM0427  Fragment51 PaTu 8988t C2230(1.43)  LDD1306  [3]
 LDCM0109  NEM HeLa N.A.  LDD0226  [2]

References

1 A quantitative thiol reactivity profiling platform to analyze redox and electrophile reactive cysteine proteomes. Nat Protoc. 2020 Sep;15(9):2891-2919. doi: 10.1038/s41596-020-0352-2. Epub 2020 Jul 20.
Mass spectrometry data entry: PXD016048
2 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.