Details of the Target

General Information of Target

Target ID LDTP10945
Target Name Pituitary homeobox 2 (PITX2)
Gene Name PITX2
Gene ID 5308
Synonyms
ARP1; RGS; RIEG; RIEG1; Pituitary homeobox 2; ALL1-responsive protein ARP1; Homeobox protein PITX2; Paired-like homeodomain transcription factor 2; RIEG bicoid-related homeobox transcription factor; Solurshin
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME
DLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSED
WRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPD
PEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVE
GAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQ
SSRIEKGNQMPLKRFSMEGISNILQSGIRQTFGSSGTDKQYLNTVIPYEKKASPPSVEDL
QMLTNILFAMKEDNEKVPTLLTDYILKVLCPT
Target Bioclass
Transcription factor
Family
Paired homeobox family, Bicoid subfamily
Subcellular location
Nucleus
Function
May play a role in myoblast differentiation. When unphosphorylated, associates with an ELAVL1-containing complex, which stabilizes cyclin mRNA and ensuring cell proliferation. Phosphorylation by AKT2 impairs this association, leading to CCND1 mRNA destabilization and progression towards differentiation.; [Isoform PTX2C]: Involved in the establishment of left-right asymmetry in the developing embryo.
Uniprot ID
Q99697
Ensemble ID
ENST00000354925.6
HGNC ID
HGNC:9005

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 9 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C152(10.00)  LDD2157  [1]
IPM
 Probe Info  		C152(5.78)  LDD2230  [2]
HPAP
 Probe Info  		3.63  LDD0062  [3]
DBIA
 Probe Info  		C277(29.06)  LDD0209  [4]
Acrolein
 Probe Info  		N.A.  LDD0222  [5]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [6]
TFBX
 Probe Info  		N.A.  LDD0027  [6]
VSF
 Probe Info  		N.A.  LDD0007  [7]
Methacrolein
 Probe Info  		N.A.  LDD0218  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C277(1.01); C152(1.01)  LDD1507  [8]
 LDCM0215  AC10 HEK-293T C277(1.04); C152(0.98)  LDD1508  [8]
 LDCM0226  AC11 HEK-293T C277(0.95); C152(1.08)  LDD1509  [8]
 LDCM0237  AC12 HEK-293T C277(1.06)  LDD1510  [8]
 LDCM0259  AC14 HEK-293T C277(0.92); C152(1.05)  LDD1512  [8]
 LDCM0270  AC15 HEK-293T C277(1.00)  LDD1513  [8]
 LDCM0276  AC17 HEK-293T C277(0.98); C152(0.98)  LDD1515  [8]
 LDCM0277  AC18 HEK-293T C277(1.02); C152(1.03)  LDD1516  [8]
 LDCM0278  AC19 HEK-293T C277(1.49); C152(1.09)  LDD1517  [8]
 LDCM0279  AC2 HEK-293T C277(1.00); C152(0.97)  LDD1518  [8]
 LDCM0280  AC20 HEK-293T C277(0.95)  LDD1519  [8]
 LDCM0281  AC21 HEK-293T C277(1.02); C152(0.95)  LDD1520  [8]
 LDCM0282  AC22 HEK-293T C277(0.98); C152(1.11)  LDD1521  [8]
 LDCM0283  AC23 HEK-293T C277(1.02)  LDD1522  [8]
 LDCM0284  AC24 HEK-293T C277(1.05)  LDD1523  [8]
 LDCM0285  AC25 HEK-293T C277(1.01); C152(1.04)  LDD1524  [8]
 LDCM0286  AC26 HEK-293T C277(1.01); C152(1.04)  LDD1525  [8]
 LDCM0287  AC27 HEK-293T C277(0.98); C152(1.18)  LDD1526  [8]
 LDCM0288  AC28 HEK-293T C277(0.95)  LDD1527  [8]
 LDCM0289  AC29 HEK-293T C277(1.62); C152(0.94)  LDD1528  [8]
 LDCM0290  AC3 HEK-293T C277(0.96); C152(1.07)  LDD1529  [8]
 LDCM0291  AC30 HEK-293T C277(0.98); C152(1.03)  LDD1530  [8]
 LDCM0292  AC31 HEK-293T C277(1.03)  LDD1531  [8]
 LDCM0293  AC32 HEK-293T C277(1.00)  LDD1532  [8]
 LDCM0294  AC33 HEK-293T C277(1.02); C152(1.00)  LDD1533  [8]
 LDCM0295  AC34 HEK-293T C277(0.99); C152(1.00)  LDD1534  [8]
 LDCM0296  AC35 HEK-293T C277(1.08); C152(0.97)  LDD1535  [8]
 LDCM0297  AC36 HEK-293T C277(0.97)  LDD1536  [8]
 LDCM0298  AC37 HEK-293T C277(1.06); C152(0.98)  LDD1537  [8]
 LDCM0299  AC38 HEK-293T C277(1.01); C152(0.95)  LDD1538  [8]
 LDCM0300  AC39 HEK-293T C277(0.95)  LDD1539  [8]
 LDCM0301  AC4 HEK-293T C277(0.96)  LDD1540  [8]
 LDCM0302  AC40 HEK-293T C277(1.01)  LDD1541  [8]
 LDCM0303  AC41 HEK-293T C277(0.96); C152(1.08)  LDD1542  [8]
 LDCM0304  AC42 HEK-293T C277(1.02); C152(0.98)  LDD1543  [8]
 LDCM0305  AC43 HEK-293T C277(0.95); C152(1.00)  LDD1544  [8]
 LDCM0306  AC44 HEK-293T C277(1.09)  LDD1545  [8]
 LDCM0307  AC45 HEK-293T C277(1.30); C152(0.98)  LDD1546  [8]
 LDCM0308  AC46 HEK-293T C277(0.90); C152(1.07)  LDD1547  [8]
 LDCM0309  AC47 HEK-293T C277(1.02)  LDD1548  [8]
 LDCM0310  AC48 HEK-293T C277(1.13)  LDD1549  [8]
 LDCM0311  AC49 HEK-293T C277(0.90); C152(1.06)  LDD1550  [8]
 LDCM0312  AC5 HEK-293T C277(1.29); C152(0.97)  LDD1551  [8]
 LDCM0313  AC50 HEK-293T C277(1.08); C152(0.92)  LDD1552  [8]
 LDCM0314  AC51 HEK-293T C277(0.99); C152(1.06)  LDD1553  [8]
 LDCM0315  AC52 HEK-293T C277(0.95)  LDD1554  [8]
 LDCM0316  AC53 HEK-293T C277(1.20); C152(1.00)  LDD1555  [8]
 LDCM0317  AC54 HEK-293T C277(0.92); C152(0.98)  LDD1556  [8]
 LDCM0318  AC55 HEK-293T C277(1.04)  LDD1557  [8]
 LDCM0319  AC56 HEK-293T C277(1.15)  LDD1558  [8]
 LDCM0320  AC57 HEK-293T C277(1.08); C152(0.97)  LDD1559  [8]
 LDCM0321  AC58 HEK-293T C277(1.04); C152(0.88)  LDD1560  [8]
 LDCM0322  AC59 HEK-293T C277(1.14); C152(0.90)  LDD1561  [8]
 LDCM0323  AC6 HEK-293T C277(0.96); C152(1.01)  LDD1562  [8]
 LDCM0324  AC60 HEK-293T C277(0.97)  LDD1563  [8]
 LDCM0325  AC61 HEK-293T C277(1.35); C152(1.00)  LDD1564  [8]
 LDCM0326  AC62 HEK-293T C277(0.96); C152(0.84)  LDD1565  [8]
 LDCM0327  AC63 HEK-293T C277(1.07)  LDD1566  [8]
 LDCM0328  AC64 HEK-293T C277(0.91)  LDD1567  [8]
 LDCM0334  AC7 HEK-293T C277(0.97)  LDD1568  [8]
 LDCM0345  AC8 HEK-293T C277(0.96)  LDD1569  [8]
 LDCM0248  AKOS034007472 HEK-293T C277(1.27); C152(1.04)  LDD1511  [8]
 LDCM0356  AKOS034007680 HEK-293T C277(0.90); C152(1.08)  LDD1570  [8]
 LDCM0275  AKOS034007705 HEK-293T C277(1.06)  LDD1514  [8]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [5]
 LDCM0367  CL1 HEK-293T C277(0.96); C152(0.96)  LDD1571  [8]
 LDCM0368  CL10 HEK-293T C277(1.07); C152(1.10)  LDD1572  [8]
 LDCM0369  CL100 HEK-293T C277(1.01); C152(1.02)  LDD1573  [8]
 LDCM0370  CL101 HEK-293T C277(1.16); C152(1.02)  LDD1574  [8]
 LDCM0371  CL102 HEK-293T C152(1.15)  LDD1575  [8]
 LDCM0372  CL103 HEK-293T C277(1.08); C152(1.04)  LDD1576  [8]
 LDCM0373  CL104 HEK-293T C277(1.07); C152(1.11)  LDD1577  [8]
 LDCM0374  CL105 HEK-293T C277(0.76); C152(1.00)  LDD1578  [8]
 LDCM0375  CL106 HEK-293T C152(1.04)  LDD1579  [8]
 LDCM0376  CL107 HEK-293T C277(1.00); C152(1.01)  LDD1580  [8]
 LDCM0377  CL108 HEK-293T C277(1.13); C152(1.04)  LDD1581  [8]
 LDCM0378  CL109 HEK-293T C277(1.02); C152(0.97)  LDD1582  [8]
 LDCM0379  CL11 HEK-293T C277(1.02)  LDD1583  [8]
 LDCM0380  CL110 HEK-293T C152(0.96)  LDD1584  [8]
 LDCM0381  CL111 HEK-293T C277(1.13); C152(1.02)  LDD1585  [8]
 LDCM0382  CL112 HEK-293T C277(1.02); C152(1.11)  LDD1586  [8]
 LDCM0383  CL113 HEK-293T C277(1.13); C152(0.94)  LDD1587  [8]
 LDCM0384  CL114 HEK-293T C152(0.95)  LDD1588  [8]
 LDCM0385  CL115 HEK-293T C277(1.11); C152(1.02)  LDD1589  [8]
 LDCM0386  CL116 HEK-293T C277(0.99); C152(1.02)  LDD1590  [8]
 LDCM0387  CL117 HEK-293T C277(1.04); C152(0.98)  LDD1591  [8]
 LDCM0388  CL118 HEK-293T C152(1.13)  LDD1592  [8]
 LDCM0389  CL119 HEK-293T C277(1.10); C152(1.14)  LDD1593  [8]
 LDCM0390  CL12 HEK-293T C277(1.07)  LDD1594  [8]
 LDCM0391  CL120 HEK-293T C277(1.03); C152(1.07)  LDD1595  [8]
 LDCM0392  CL121 HEK-293T C277(1.07); C152(1.10)  LDD1596  [8]
 LDCM0393  CL122 HEK-293T C152(1.07)  LDD1597  [8]
 LDCM0394  CL123 HEK-293T C277(1.17); C152(1.03)  LDD1598  [8]
 LDCM0395  CL124 HEK-293T C277(1.09); C152(1.13)  LDD1599  [8]
 LDCM0396  CL125 HEK-293T C277(0.94); C152(0.99)  LDD1600  [8]
 LDCM0397  CL126 HEK-293T C152(1.05)  LDD1601  [8]
 LDCM0398  CL127 HEK-293T C277(1.03); C152(0.99)  LDD1602  [8]
 LDCM0399  CL128 HEK-293T C277(1.02); C152(0.97)  LDD1603  [8]
 LDCM0400  CL13 HEK-293T C277(1.48); C152(1.07)  LDD1604  [8]
 LDCM0401  CL14 HEK-293T C152(1.10)  LDD1605  [8]
 LDCM0402  CL15 HEK-293T C277(1.19); C152(1.07)  LDD1606  [8]
 LDCM0403  CL16 HEK-293T C277(1.03); C152(1.14)  LDD1607  [8]
 LDCM0404  CL17 HEK-293T C277(0.90); C152(1.13)  LDD1608  [8]
 LDCM0405  CL18 HEK-293T C277(0.97); C152(1.01)  LDD1609  [8]
 LDCM0406  CL19 HEK-293T C277(1.08); C152(1.17)  LDD1610  [8]
 LDCM0407  CL2 HEK-293T C152(1.03)  LDD1611  [8]
 LDCM0408  CL20 HEK-293T C277(1.09)  LDD1612  [8]
 LDCM0409  CL21 HEK-293T C277(1.04); C152(0.97)  LDD1613  [8]
 LDCM0410  CL22 HEK-293T C277(1.00); C152(1.16)  LDD1614  [8]
 LDCM0411  CL23 HEK-293T C277(1.10)  LDD1615  [8]
 LDCM0412  CL24 HEK-293T C277(1.05)  LDD1616  [8]
 LDCM0413  CL25 HEK-293T C277(1.10); C152(0.96)  LDD1617  [8]
 LDCM0414  CL26 HEK-293T C152(1.05)  LDD1618  [8]
 LDCM0415  CL27 HEK-293T C277(0.96); C152(1.00)  LDD1619  [8]
 LDCM0416  CL28 HEK-293T C277(1.06); C152(1.21)  LDD1620  [8]
 LDCM0417  CL29 HEK-293T C277(0.96); C152(1.08)  LDD1621  [8]
 LDCM0418  CL3 HEK-293T C277(1.17); C152(0.99)  LDD1622  [8]
 LDCM0419  CL30 HEK-293T C277(0.91); C152(1.04)  LDD1623  [8]
 LDCM0420  CL31 HEK-293T C277(1.06); C152(1.06)  LDD1624  [8]
 LDCM0421  CL32 HEK-293T C277(1.03)  LDD1625  [8]
 LDCM0422  CL33 HEK-293T C277(1.20); C152(1.12)  LDD1626  [8]
 LDCM0423  CL34 HEK-293T C277(0.96); C152(1.04)  LDD1627  [8]
 LDCM0424  CL35 HEK-293T C277(0.97)  LDD1628  [8]
 LDCM0425  CL36 HEK-293T C277(1.06)  LDD1629  [8]
 LDCM0426  CL37 HEK-293T C277(0.97); C152(0.98)  LDD1630  [8]
 LDCM0428  CL39 HEK-293T C277(0.91); C152(1.05)  LDD1632  [8]
 LDCM0429  CL4 HEK-293T C277(1.08); C152(1.06)  LDD1633  [8]
 LDCM0430  CL40 HEK-293T C277(1.04); C152(0.99)  LDD1634  [8]
 LDCM0431  CL41 HEK-293T C277(0.95); C152(1.06)  LDD1635  [8]
 LDCM0432  CL42 HEK-293T C277(1.01); C152(0.95)  LDD1636  [8]
 LDCM0433  CL43 HEK-293T C277(0.98); C152(1.12)  LDD1637  [8]
 LDCM0434  CL44 HEK-293T C277(1.00)  LDD1638  [8]
 LDCM0435  CL45 HEK-293T C277(1.54); C152(1.14)  LDD1639  [8]
 LDCM0436  CL46 HEK-293T C277(1.00); C152(1.11)  LDD1640  [8]
 LDCM0437  CL47 HEK-293T C277(1.11)  LDD1641  [8]
 LDCM0438  CL48 HEK-293T C277(0.90)  LDD1642  [8]
 LDCM0439  CL49 HEK-293T C277(0.89); C152(1.00)  LDD1643  [8]
 LDCM0440  CL5 HEK-293T C277(1.14); C152(1.03)  LDD1644  [8]
 LDCM0441  CL50 HEK-293T C152(1.02)  LDD1645  [8]
 LDCM0443  CL52 HEK-293T C277(1.19); C152(1.04)  LDD1646  [8]
 LDCM0444  CL53 HEK-293T C277(1.00); C152(1.04)  LDD1647  [8]
 LDCM0445  CL54 HEK-293T C277(1.11); C152(1.04)  LDD1648  [8]
 LDCM0446  CL55 HEK-293T C277(1.13); C152(1.17)  LDD1649  [8]
 LDCM0447  CL56 HEK-293T C277(1.06)  LDD1650  [8]
 LDCM0448  CL57 HEK-293T C277(1.46); C152(1.07)  LDD1651  [8]
 LDCM0449  CL58 HEK-293T C277(0.99); C152(1.11)  LDD1652  [8]
 LDCM0450  CL59 HEK-293T C277(1.02)  LDD1653  [8]
 LDCM0451  CL6 HEK-293T C277(1.01); C152(0.95)  LDD1654  [8]
 LDCM0452  CL60 HEK-293T C277(1.13)  LDD1655  [8]
 LDCM0453  CL61 HEK-293T C277(0.95); C152(0.99)  LDD1656  [8]
 LDCM0454  CL62 HEK-293T C152(1.02)  LDD1657  [8]
 LDCM0455  CL63 HEK-293T C277(1.24); C152(1.00)  LDD1658  [8]
 LDCM0456  CL64 HEK-293T C277(1.03); C152(0.99)  LDD1659  [8]
 LDCM0457  CL65 HEK-293T C277(1.04); C152(1.02)  LDD1660  [8]
 LDCM0458  CL66 HEK-293T C277(1.04); C152(1.06)  LDD1661  [8]
 LDCM0459  CL67 HEK-293T C277(0.89); C152(1.20)  LDD1662  [8]
 LDCM0460  CL68 HEK-293T C277(1.02)  LDD1663  [8]
 LDCM0461  CL69 HEK-293T C277(1.10); C152(1.07)  LDD1664  [8]
 LDCM0462  CL7 HEK-293T C277(0.96); C152(1.14)  LDD1665  [8]
 LDCM0463  CL70 HEK-293T C277(1.09); C152(1.05)  LDD1666  [8]
 LDCM0464  CL71 HEK-293T C277(1.06)  LDD1667  [8]
 LDCM0465  CL72 HEK-293T C277(1.28)  LDD1668  [8]
 LDCM0466  CL73 HEK-293T C277(1.03); C152(1.00)  LDD1669  [8]
 LDCM0467  CL74 HEK-293T C152(0.98)  LDD1670  [8]
 LDCM0469  CL76 HEK-293T C277(1.02); C152(1.05)  LDD1672  [8]
 LDCM0470  CL77 HEK-293T C277(0.96); C152(1.12)  LDD1673  [8]
 LDCM0471  CL78 HEK-293T C277(1.02); C152(1.02)  LDD1674  [8]
 LDCM0472  CL79 HEK-293T C277(0.98); C152(1.03)  LDD1675  [8]
 LDCM0473  CL8 HEK-293T C277(1.13)  LDD1676  [8]
 LDCM0474  CL80 HEK-293T C277(0.90)  LDD1677  [8]
 LDCM0475  CL81 HEK-293T C277(1.29); C152(1.02)  LDD1678  [8]
 LDCM0476  CL82 HEK-293T C277(0.99); C152(1.05)  LDD1679  [8]
 LDCM0477  CL83 HEK-293T C277(1.08)  LDD1680  [8]
 LDCM0478  CL84 HEK-293T C277(0.93)  LDD1681  [8]
 LDCM0479  CL85 HEK-293T C277(0.95); C152(1.02)  LDD1682  [8]
 LDCM0480  CL86 HEK-293T C152(0.98)  LDD1683  [8]
 LDCM0481  CL87 HEK-293T C277(1.00); C152(0.98)  LDD1684  [8]
 LDCM0482  CL88 HEK-293T C277(1.06); C152(0.97)  LDD1685  [8]
 LDCM0483  CL89 HEK-293T C277(1.02); C152(1.04)  LDD1686  [8]
 LDCM0484  CL9 HEK-293T C277(1.15); C152(1.06)  LDD1687  [8]
 LDCM0485  CL90 HEK-293T C277(1.15); C152(1.03)  LDD1688  [8]
 LDCM0486  CL91 HEK-293T C277(1.15); C152(1.01)  LDD1689  [8]
 LDCM0487  CL92 HEK-293T C277(0.99)  LDD1690  [8]
 LDCM0488  CL93 HEK-293T C277(1.10); C152(0.99)  LDD1691  [8]
 LDCM0489  CL94 HEK-293T C277(0.94); C152(1.06)  LDD1692  [8]
 LDCM0490  CL95 HEK-293T C277(1.35)  LDD1693  [8]
 LDCM0491  CL96 HEK-293T C277(1.01)  LDD1694  [8]
 LDCM0492  CL97 HEK-293T C277(1.05); C152(1.05)  LDD1695  [8]
 LDCM0493  CL98 HEK-293T C152(1.02)  LDD1696  [8]
 LDCM0494  CL99 HEK-293T C277(0.99); C152(0.99)  LDD1697  [8]
 LDCM0495  E2913 HEK-293T C277(0.94); C152(1.01)  LDD1698  [8]
 LDCM0468  Fragment33 HEK-293T C277(1.05); C152(1.05)  LDD1671  [8]
 LDCM0427  Fragment51 HEK-293T C152(1.07)  LDD1631  [8]
 LDCM0022  KB02 A673 C159(2.33)  LDD2261  [9]
 LDCM0023  KB03 Jurkat C277(29.06)  LDD0209  [4]
 LDCM0024  KB05 NCI-N87 C159(1.56)  LDD3364  [9]
 LDCM0014  Panhematin HEK-293T 3.63  LDD0062  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Tubulointerstitial nephritis antigen-like (TINAGL1) Peptidase C1 family Q9GZM7
Inactive Ufm1-specific protease 1 (UFSP1) Peptidase C78 family Q6NVU6
Proteasome subunit beta type-4 (PSMB4) Peptidase T1B family P28070
Tribbles homolog 3 (TRIB3) CAMK Ser/Thr protein kinase family Q96RU7
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1) HEY family Q9Y5J3
Transcription factor
Click To Hide/Show 6 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein Hox-A1 (HOXA1) Antp homeobox family P49639
Myocyte-specific enhancer factor 2A (MEF2A) MEF2 family Q02078
POU domain class 2-associating factor 1 (POU2AF1) POU2AF family Q16633
Y-box-binding protein 1 (YBX1) YBX1 family P67809
Forkhead box protein C1 (FOXC1) . Q12948
T-box transcription factor TBX22 (TBX22) . Q9Y458
Other
Click To Hide/Show 15 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cysteine-rich tail protein 1 (CYSRT1) CYSRT1 family A8MQ03
DNA damage-inducible transcript 4-like protein (DDIT4L) DDIT4 family Q96D03
Dynein light chain Tctex-type 1 (DYNLT1) Dynein light chain Tctex-type family P63172
Keratin, type I cuticular Ha4 (KRT34) Intermediate filament family O76011
Keratin-associated protein 19-5 (KRTAP19-5) KRTAP type 19 family Q3LI72
Keratin-associated protein 19-7 (KRTAP19-7) KRTAP type 19 family Q3SYF9
Keratin-associated protein 3-3 (KRTAP3-3) KRTAP type 3 family Q9BYR6
Keratin-associated protein 6-1 (KRTAP6-1) KRTAP type 6 family Q3LI64
Keratin-associated protein 7-1 (KRTAP7-1) KRTAP type 7 family Q8IUC3
Protein Mis18-beta (OIP5) Mis18 family O43482
Keratin-associated protein 15-1 (KRTAP15-1) PMG family Q3LI76
Prefoldin subunit 5 (PFDN5) Prefoldin subunit alpha family Q99471
DAZ-associated protein 2 (DAZAP2) . Q15038
Protein SPMIP9 (SPMIP9) . Q96LM6
TNF receptor-associated factor 1 (TRAF1) . Q13077

References

1 From chemoproteomic-detected amino acids to genomic coordinates: insights into precise multi-omic data integration. Mol Syst Biol. 2021 Feb;17(2):e9840. doi: 10.15252/msb.20209840.
Mass spectrometry data entry: PXD022151
2 A quantitative thiol reactivity profiling platform to analyze redox and electrophile reactive cysteine proteomes. Nat Protoc. 2020 Sep;15(9):2891-2919. doi: 10.1038/s41596-020-0352-2. Epub 2020 Jul 20.
Mass spectrometry data entry: PXD016048
3 A Chemical Proteomic Map of Heme-Protein Interactions. J Am Chem Soc. 2022 Aug 24;144(33):15013-15019. doi: 10.1021/jacs.2c06104. Epub 2022 Aug 12.
Mass spectrometry data entry: PXD034651
4 Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.
5 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
6 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
7 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
8 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
9 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840