Details of the Target

General Information of Target

Target ID LDTP10622
Target Name Zinc finger protein 830 (ZNF830)
Gene Name ZNF830
Gene ID 91603
Synonyms
CCDC16; Zinc finger protein 830; Coiled-coil domain-containing protein 16
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEADLSGFNIDAPRWDQRTFLGRVKHFLNITDPRTVFVSERELDWAKVMVEKSRMGVVPP
GTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGMIITGFMLQFYRTMPAVIFWQ
WVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAVGMNMLTKKAPPLVGRWVP
FAAVAAANCVNIPMMRQQELIKGICVKDRNENEIGHSRRAAAIGITQVVISRITMSAPGM
ILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFLIFMVPVACGLFPQKCELPVSYLEPK
LQDTIKAKYGELEPYVYFNKGL
Target Bioclass
Other
Subcellular location
Nucleus
Function
May play a role in pre-mRNA splicing as component of the spliceosome. Acts as an important regulator of the cell cycle that participates in the maintenance of genome integrity. During cell cycle progression in embryonic fibroblast, prevents replication fork collapse, double-strand break formation and cell cycle checkpoint activation. Controls mitotic cell cycle progression and cell survival in rapidly proliferating intestinal epithelium and embryonic stem cells. During the embryo preimplantation, controls different aspects of M phase. During early oocyte growth, plays a role in oocyte survival by preventing chromosomal breaks formation, activation of TP63 and reduction of transcription.
Uniprot ID
Q96NB3
Ensemble ID
ENST00000361952.5
HGNC ID
HGNC:28291

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 8 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K83(0.26)  LDD0277  [1]
Probe 1
 Probe Info  		Y315(10.84)  LDD3495  [2]
DBIA
 Probe Info  		C314(1.45)  LDD0080  [3]
m-APA
 Probe Info  		H222(0.00); H99(0.00)  LDD2231  [4]
IA-alkyne
 Probe Info  		N.A.  LDD0162  [5]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [6]
IPM
 Probe Info  		N.A.  LDD2156  [7]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [8]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C314(1.12)  LDD0531  [3]
 LDCM0215  AC10 HEK-293T C314(1.02)  LDD1508  [9]
 LDCM0216  AC100 HCT 116 C314(0.80)  LDD0533  [3]
 LDCM0217  AC101 HCT 116 C314(0.94)  LDD0534  [3]
 LDCM0218  AC102 HCT 116 C314(0.97)  LDD0535  [3]
 LDCM0219  AC103 HCT 116 C314(1.62)  LDD0536  [3]
 LDCM0220  AC104 HCT 116 C314(1.33)  LDD0537  [3]
 LDCM0221  AC105 HCT 116 C314(0.95)  LDD0538  [3]
 LDCM0222  AC106 HCT 116 C314(1.07)  LDD0539  [3]
 LDCM0223  AC107 HCT 116 C314(1.16)  LDD0540  [3]
 LDCM0224  AC108 HCT 116 C314(1.26)  LDD0541  [3]
 LDCM0225  AC109 HCT 116 C314(1.36)  LDD0542  [3]
 LDCM0226  AC11 HEK-293T C314(0.96)  LDD1509  [9]
 LDCM0227  AC110 HCT 116 C314(0.84)  LDD0544  [3]
 LDCM0228  AC111 HCT 116 C314(0.82)  LDD0545  [3]
 LDCM0229  AC112 HCT 116 C314(0.88)  LDD0546  [3]
 LDCM0230  AC113 HCT 116 C314(0.98)  LDD0547  [3]
 LDCM0231  AC114 HCT 116 C314(0.96)  LDD0548  [3]
 LDCM0232  AC115 HCT 116 C314(1.14)  LDD0549  [3]
 LDCM0233  AC116 HCT 116 C314(1.51)  LDD0550  [3]
 LDCM0234  AC117 HCT 116 C314(1.24)  LDD0551  [3]
 LDCM0235  AC118 HCT 116 C314(1.00)  LDD0552  [3]
 LDCM0236  AC119 HCT 116 C314(1.25)  LDD0553  [3]
 LDCM0237  AC12 HEK-293T C314(1.05)  LDD1510  [9]
 LDCM0238  AC120 HCT 116 C314(1.44)  LDD0555  [3]
 LDCM0239  AC121 HCT 116 C314(1.16)  LDD0556  [3]
 LDCM0240  AC122 HCT 116 C314(1.21)  LDD0557  [3]
 LDCM0241  AC123 HCT 116 C314(1.17)  LDD0558  [3]
 LDCM0242  AC124 HCT 116 C314(1.14)  LDD0559  [3]
 LDCM0243  AC125 HCT 116 C314(0.95)  LDD0560  [3]
 LDCM0244  AC126 HCT 116 C314(1.31)  LDD0561  [3]
 LDCM0245  AC127 HCT 116 C314(1.44)  LDD0562  [3]
 LDCM0259  AC14 HEK-293T C314(1.02)  LDD1512  [9]
 LDCM0270  AC15 HEK-293T C314(1.02)  LDD1513  [9]
 LDCM0276  AC17 HEK-293T C314(1.00)  LDD1515  [9]
 LDCM0277  AC18 HEK-293T C314(1.11)  LDD1516  [9]
 LDCM0278  AC19 HEK-293T C314(0.85)  LDD1517  [9]
 LDCM0279  AC2 HCT 116 C314(1.04)  LDD0596  [3]
 LDCM0280  AC20 HEK-293T C314(1.02)  LDD1519  [9]
 LDCM0281  AC21 HEK-293T C314(1.08)  LDD1520  [9]
 LDCM0282  AC22 HEK-293T C314(1.04)  LDD1521  [9]
 LDCM0283  AC23 HEK-293T C314(0.95)  LDD1522  [9]
 LDCM0284  AC24 HEK-293T C314(0.96)  LDD1523  [9]
 LDCM0285  AC25 HEK-293T C314(0.99)  LDD1524  [9]
 LDCM0286  AC26 HEK-293T C314(0.97)  LDD1525  [9]
 LDCM0287  AC27 HEK-293T C314(0.90)  LDD1526  [9]
 LDCM0288  AC28 HEK-293T C314(0.97)  LDD1527  [9]
 LDCM0289  AC29 HEK-293T C314(0.98)  LDD1528  [9]
 LDCM0290  AC3 HCT 116 C314(1.18)  LDD0607  [3]
 LDCM0291  AC30 HEK-293T C314(0.98)  LDD1530  [9]
 LDCM0292  AC31 HEK-293T C314(0.90)  LDD1531  [9]
 LDCM0293  AC32 HEK-293T C314(0.99)  LDD1532  [9]
 LDCM0294  AC33 HEK-293T C314(1.14)  LDD1533  [9]
 LDCM0295  AC34 HEK-293T C314(1.07)  LDD1534  [9]
 LDCM0296  AC35 HCT 116 C314(1.03)  LDD0613  [3]
 LDCM0297  AC36 HCT 116 C314(1.20)  LDD0614  [3]
 LDCM0298  AC37 HCT 116 C314(0.96)  LDD0615  [3]
 LDCM0299  AC38 HCT 116 C314(1.01)  LDD0616  [3]
 LDCM0300  AC39 HCT 116 C314(1.13)  LDD0617  [3]
 LDCM0301  AC4 HCT 116 C314(1.15)  LDD0618  [3]
 LDCM0302  AC40 HCT 116 C314(1.09)  LDD0619  [3]
 LDCM0303  AC41 HCT 116 C314(1.06)  LDD0620  [3]
 LDCM0304  AC42 HCT 116 C314(1.10)  LDD0621  [3]
 LDCM0305  AC43 HCT 116 C314(1.48)  LDD0622  [3]
 LDCM0306  AC44 HCT 116 C314(1.15)  LDD0623  [3]
 LDCM0307  AC45 HCT 116 C314(1.17)  LDD0624  [3]
 LDCM0308  AC46 HEK-293T C314(0.93)  LDD0906  [3]
 LDCM0309  AC47 HEK-293T C314(1.31)  LDD0907  [3]
 LDCM0310  AC48 HEK-293T C314(1.14)  LDD0908  [3]
 LDCM0311  AC49 HEK-293T C314(1.03)  LDD0909  [3]
 LDCM0312  AC5 HCT 116 C314(1.12)  LDD0629  [3]
 LDCM0313  AC50 HEK-293T C314(1.37)  LDD0911  [3]
 LDCM0314  AC51 HEK-293T C314(1.08)  LDD0912  [3]
 LDCM0315  AC52 HEK-293T C314(1.29)  LDD0913  [3]
 LDCM0316  AC53 HEK-293T C314(0.97)  LDD0914  [3]
 LDCM0317  AC54 HEK-293T C314(1.10)  LDD0915  [3]
 LDCM0318  AC55 HEK-293T C314(1.09)  LDD0916  [3]
 LDCM0319  AC56 HEK-293T C314(0.88)  LDD0917  [3]
 LDCM0320  AC57 HEK-293T C314(1.05)  LDD1559  [9]
 LDCM0321  AC58 HEK-293T C314(0.99)  LDD1560  [9]
 LDCM0322  AC59 HEK-293T C314(1.03)  LDD1561  [9]
 LDCM0323  AC6 HEK-293T C314(1.00)  LDD1562  [9]
 LDCM0324  AC60 HEK-293T C314(1.06)  LDD1563  [9]
 LDCM0325  AC61 HEK-293T C314(1.02)  LDD1564  [9]
 LDCM0326  AC62 HEK-293T C314(0.98)  LDD1565  [9]
 LDCM0327  AC63 HEK-293T C314(0.89)  LDD1566  [9]
 LDCM0328  AC64 HEK-293T C314(0.97)  LDD1567  [9]
 LDCM0334  AC7 HEK-293T C314(0.90)  LDD1568  [9]
 LDCM0345  AC8 HEK-293T C314(1.00)  LDD1569  [9]
 LDCM0365  AC98 HCT 116 C314(3.32)  LDD0682  [3]
 LDCM0366  AC99 HCT 116 C314(0.70)  LDD0683  [3]
 LDCM0248  AKOS034007472 HEK-293T C314(0.98)  LDD1511  [9]
 LDCM0356  AKOS034007680 HEK-293T C314(1.12)  LDD1570  [9]
 LDCM0275  AKOS034007705 HEK-293T C314(0.89)  LDD1514  [9]
 LDCM0367  CL1 HEK-293T C314(0.92)  LDD1571  [9]
 LDCM0368  CL10 HEK-293T C314(0.91)  LDD1572  [9]
 LDCM0369  CL100 HCT 116 C314(1.16)  LDD0686  [3]
 LDCM0370  CL101 HEK-293T C314(1.02)  LDD1574  [9]
 LDCM0371  CL102 HEK-293T C314(0.93)  LDD1575  [9]
 LDCM0372  CL103 HEK-293T C314(0.97)  LDD1576  [9]
 LDCM0373  CL104 HEK-293T C314(0.92)  LDD1577  [9]
 LDCM0374  CL105 HEK-293T C314(0.91)  LDD1578  [9]
 LDCM0375  CL106 HEK-293T C314(0.98)  LDD1579  [9]
 LDCM0376  CL107 HEK-293T C314(0.96)  LDD1580  [9]
 LDCM0377  CL108 HEK-293T C314(0.97)  LDD1581  [9]
 LDCM0378  CL109 HEK-293T C314(0.95)  LDD1582  [9]
 LDCM0379  CL11 HEK-293T C314(0.95)  LDD1583  [9]
 LDCM0380  CL110 HEK-293T C314(0.82)  LDD1584  [9]
 LDCM0381  CL111 HEK-293T C314(0.95)  LDD1585  [9]
 LDCM0382  CL112 HEK-293T C314(1.03)  LDD1586  [9]
 LDCM0383  CL113 HEK-293T C314(0.97)  LDD1587  [9]
 LDCM0384  CL114 HEK-293T C314(0.95)  LDD1588  [9]
 LDCM0385  CL115 HEK-293T C314(0.96)  LDD1589  [9]
 LDCM0386  CL116 HEK-293T C314(0.96)  LDD1590  [9]
 LDCM0387  CL117 HCT 116 C314(1.14)  LDD0704  [3]
 LDCM0388  CL118 HCT 116 C314(1.14)  LDD0705  [3]
 LDCM0389  CL119 HCT 116 C314(1.43)  LDD0706  [3]
 LDCM0390  CL12 HEK-293T C314(0.95)  LDD1594  [9]
 LDCM0391  CL120 HCT 116 C314(1.32)  LDD0708  [3]
 LDCM0392  CL121 HEK-293T C314(0.93)  LDD0990  [3]
 LDCM0393  CL122 HEK-293T C314(1.02)  LDD0991  [3]
 LDCM0394  CL123 HEK-293T C314(0.98)  LDD0992  [3]
 LDCM0395  CL124 HEK-293T C314(0.88)  LDD0993  [3]
 LDCM0396  CL125 HEK-293T C314(1.16)  LDD1600  [9]
 LDCM0397  CL126 HEK-293T C314(0.95)  LDD1601  [9]
 LDCM0398  CL127 HEK-293T C314(0.92)  LDD1602  [9]
 LDCM0399  CL128 HEK-293T C314(0.98)  LDD1603  [9]
 LDCM0400  CL13 HEK-293T C314(0.93)  LDD1604  [9]
 LDCM0401  CL14 HEK-293T C314(1.09)  LDD1605  [9]
 LDCM0402  CL15 HEK-293T C314(0.95)  LDD1606  [9]
 LDCM0403  CL16 HEK-293T C314(0.95)  LDD1607  [9]
 LDCM0404  CL17 HEK-293T C314(1.03)  LDD1608  [9]
 LDCM0405  CL18 HEK-293T C314(1.05)  LDD1609  [9]
 LDCM0406  CL19 HEK-293T C314(1.03)  LDD1610  [9]
 LDCM0407  CL2 HEK-293T C314(1.00)  LDD1611  [9]
 LDCM0408  CL20 HEK-293T C314(1.09)  LDD1612  [9]
 LDCM0409  CL21 HEK-293T C314(1.03)  LDD1613  [9]
 LDCM0410  CL22 HEK-293T C314(1.02)  LDD1614  [9]
 LDCM0411  CL23 HEK-293T C314(1.02)  LDD1615  [9]
 LDCM0412  CL24 HEK-293T C314(1.01)  LDD1616  [9]
 LDCM0413  CL25 HEK-293T C314(0.94)  LDD1617  [9]
 LDCM0414  CL26 HEK-293T C314(0.97)  LDD1618  [9]
 LDCM0415  CL27 HEK-293T C314(0.90)  LDD1619  [9]
 LDCM0416  CL28 HEK-293T C314(0.97)  LDD1620  [9]
 LDCM0417  CL29 HEK-293T C314(1.06)  LDD1621  [9]
 LDCM0418  CL3 HEK-293T C314(0.87)  LDD1622  [9]
 LDCM0419  CL30 HEK-293T C314(0.96)  LDD1623  [9]
 LDCM0420  CL31 HEK-293T C314(1.16)  LDD1624  [9]
 LDCM0421  CL32 HEK-293T C314(1.09)  LDD1625  [9]
 LDCM0422  CL33 HEK-293T C314(0.96)  LDD1626  [9]
 LDCM0423  CL34 HEK-293T C314(1.09)  LDD1627  [9]
 LDCM0424  CL35 HEK-293T C314(1.02)  LDD1628  [9]
 LDCM0425  CL36 HEK-293T C314(1.02)  LDD1629  [9]
 LDCM0426  CL37 HEK-293T C314(1.05)  LDD1630  [9]
 LDCM0428  CL39 HEK-293T C314(0.99)  LDD1632  [9]
 LDCM0429  CL4 HEK-293T C314(1.04)  LDD1633  [9]
 LDCM0430  CL40 HEK-293T C314(0.97)  LDD1634  [9]
 LDCM0431  CL41 HEK-293T C314(1.14)  LDD1635  [9]
 LDCM0432  CL42 HEK-293T C314(1.04)  LDD1636  [9]
 LDCM0433  CL43 HEK-293T C314(1.02)  LDD1637  [9]
 LDCM0434  CL44 HEK-293T C314(1.03)  LDD1638  [9]
 LDCM0435  CL45 HEK-293T C314(1.00)  LDD1639  [9]
 LDCM0436  CL46 HEK-293T C314(2.34)  LDD1034  [3]
 LDCM0437  CL47 HEK-293T C314(2.70)  LDD1035  [3]
 LDCM0438  CL48 HEK-293T C314(2.23)  LDD1036  [3]
 LDCM0439  CL49 HEK-293T C314(1.40)  LDD1037  [3]
 LDCM0440  CL5 HEK-293T C314(1.18)  LDD1644  [9]
 LDCM0441  CL50 HEK-293T C314(3.14)  LDD1039  [3]
 LDCM0442  CL51 HEK-293T C314(1.80)  LDD1040  [3]
 LDCM0443  CL52 HEK-293T C314(1.07)  LDD1041  [3]
 LDCM0444  CL53 HEK-293T C314(1.01)  LDD1042  [3]
 LDCM0445  CL54 HEK-293T C314(1.32)  LDD1043  [3]
 LDCM0446  CL55 HEK-293T C314(1.98)  LDD1044  [3]
 LDCM0447  CL56 HEK-293T C314(1.38)  LDD1045  [3]
 LDCM0448  CL57 HEK-293T C314(1.55)  LDD1046  [3]
 LDCM0449  CL58 HEK-293T C314(1.52)  LDD1047  [3]
 LDCM0450  CL59 HEK-293T C314(1.66)  LDD1048  [3]
 LDCM0451  CL6 HEK-293T C314(1.09)  LDD1654  [9]
 LDCM0452  CL60 HEK-293T C314(1.79)  LDD1050  [3]
 LDCM0453  CL61 HCT 116 C314(1.52)  LDD0770  [3]
 LDCM0454  CL62 HCT 116 C314(1.19)  LDD0771  [3]
 LDCM0455  CL63 HCT 116 C314(1.21)  LDD0772  [3]
 LDCM0456  CL64 HCT 116 C314(1.38)  LDD0773  [3]
 LDCM0457  CL65 HCT 116 C314(1.32)  LDD0774  [3]
 LDCM0458  CL66 HCT 116 C314(1.22)  LDD0775  [3]
 LDCM0459  CL67 HCT 116 C314(1.18)  LDD0776  [3]
 LDCM0460  CL68 HCT 116 C314(1.26)  LDD0777  [3]
 LDCM0461  CL69 HCT 116 C314(1.42)  LDD0778  [3]
 LDCM0462  CL7 HEK-293T C314(1.09)  LDD1665  [9]
 LDCM0463  CL70 HCT 116 C314(1.40)  LDD0780  [3]
 LDCM0464  CL71 HCT 116 C314(1.36)  LDD0781  [3]
 LDCM0465  CL72 HCT 116 C314(1.53)  LDD0782  [3]
 LDCM0466  CL73 HCT 116 C314(1.41)  LDD0783  [3]
 LDCM0467  CL74 HCT 116 C314(1.15)  LDD0784  [3]
 LDCM0469  CL76 HEK-293T C314(0.99)  LDD1672  [9]
 LDCM0470  CL77 HEK-293T C314(1.02)  LDD1673  [9]
 LDCM0471  CL78 HEK-293T C314(1.06)  LDD1674  [9]
 LDCM0472  CL79 HEK-293T C314(0.95)  LDD1675  [9]
 LDCM0473  CL8 HEK-293T C314(0.86)  LDD1676  [9]
 LDCM0474  CL80 HEK-293T C314(1.05)  LDD1677  [9]
 LDCM0475  CL81 HEK-293T C314(1.05)  LDD1678  [9]
 LDCM0476  CL82 HEK-293T C314(0.94)  LDD1679  [9]
 LDCM0477  CL83 HEK-293T C314(1.00)  LDD1680  [9]
 LDCM0478  CL84 HEK-293T C314(0.99)  LDD1681  [9]
 LDCM0479  CL85 HEK-293T C314(1.02)  LDD1682  [9]
 LDCM0480  CL86 HEK-293T C314(0.98)  LDD1683  [9]
 LDCM0481  CL87 HEK-293T C314(1.06)  LDD1684  [9]
 LDCM0482  CL88 HEK-293T C314(1.05)  LDD1685  [9]
 LDCM0483  CL89 HEK-293T C314(1.11)  LDD1686  [9]
 LDCM0484  CL9 HEK-293T C314(1.16)  LDD1687  [9]
 LDCM0485  CL90 HEK-293T C314(0.86)  LDD1688  [9]
 LDCM0486  CL91 HCT 116 C314(1.03)  LDD0803  [3]
 LDCM0487  CL92 HCT 116 C314(0.89)  LDD0804  [3]
 LDCM0488  CL93 HCT 116 C314(0.98)  LDD0805  [3]
 LDCM0489  CL94 HCT 116 C314(1.01)  LDD0806  [3]
 LDCM0490  CL95 HCT 116 C314(1.09)  LDD0807  [3]
 LDCM0491  CL96 HCT 116 C314(1.13)  LDD0808  [3]
 LDCM0492  CL97 HCT 116 C314(1.13)  LDD0809  [3]
 LDCM0493  CL98 HCT 116 C314(1.12)  LDD0810  [3]
 LDCM0494  CL99 HCT 116 C314(0.98)  LDD0811  [3]
 LDCM0495  E2913 HEK-293T C314(1.01)  LDD1698  [9]
 LDCM0468  Fragment33 HCT 116 C314(1.24)  LDD0785  [3]
 LDCM0427  Fragment51 HEK-293T C314(0.94)  LDD1631  [9]
 LDCM0022  KB02 HCT 116 C314(1.45)  LDD0080  [3]
 LDCM0023  KB03 HCT 116 C314(0.99)  LDD0081  [3]
 LDCM0024  KB05 HCT 116 C314(1.17)  LDD0082  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
RNA helicase aquarius (AQR) CWF11 family O60306
RING-type E3 ubiquitin-protein ligase PPIL2 (PPIL2) Cyclophilin-type PPIase family Q13356
Cytokine and receptor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein Red (IK) RED family Q13123
Other
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
SNW domain-containing protein 1 (SNW1) SNW family Q13573
SEC14 domain and spectrin repeat-containing protein 1 (SESTD1) SOLO family Q86VW0
Poly(rC)-binding protein 1 (PCBP1) . Q15365
Pre-mRNA-processing-splicing factor 8 (PRPF8) . Q6P2Q9
Splicing factor 3B subunit 2 (SF3B2) . Q13435

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
5 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
6 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
7 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
8 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
9 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402