Details of the Target

General Information of Target

Target ID LDTP09600
Target Name AFG1-like ATPase (AFG1L)
Gene Name AFG1L
Gene ID 246269
Synonyms
AFG1; LACE1; AFG1-like ATPase; Lactation elevated protein 1; EC 3.6.-.-; Protein AFG1 homolog
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAASWSLLVTLRPLAQSPLRGRCVGCGAWAAALAPLATAPGKPFWKAYTVQTSESMTPTA
TSETYLKALAVCHGPLDHYDFLIKAHELKDDEHQRRVIQCLQKLHEDLKGYNIEAEGLFS
KLFSRSKPPRGLYVYGDVGTGKTMVMDMFYAYVEMKRKKRVHFHGFMLDVHKRIHRLKQS
LPKRKPGFMAKSYDPIAPIAEEISEEACLLCFDEFQVTDIADAMILKQLFENLFKNGVVV
VATSNRPPEDLYKNGLQRANFVPFIAVLKEYCNTVQLDSGIDYRKRELPAAGKLYYLTSE
ADVEAVMDKLFDELAQKQNDLTRPRILKVQGRELRLNKACGTVADCTFEELCERPLGASD
YLELSKNFDTIFLRNIPQFTLANRTQGRRFITLIDNFYDLKVRIICSASTPISSLFLHQH
HDSELEQSRILMDDLGLSQDSAEGLSMFTGEEEIFAFQRTISRLTEMQTEQYWNEGDRTK
K
Target Bioclass
Enzyme
Family
AFG1 ATPase family
Subcellular location
Mitochondrion membrane
Function
Putative mitochondrial ATPase. Plays a role in mitochondrial morphology and mitochondrial protein metabolism. Promotes degradation of excess nuclear-encoded complex IV subunits (COX4I1, COX5A and COX6A1) and normal activity of complexes III and IV of the respiratory chain. Mediates mitochondrial translocation of TP53 and its transcription-independent apoptosis in response to genotoxic stress.
Uniprot ID
Q8WV93
Ensemble ID
ENST00000368977.9
HGNC ID
HGNC:16411

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K178(8.33)  LDD0277  [1]
IPM
 Probe Info  		N.A.  LDD0241  [2]
DBIA
 Probe Info  		C100(28.51)  LDD0209  [3]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [4]
TFBX
 Probe Info  		N.A.  LDD0148  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C340(1.23); C352(1.05)  LDD0812  [6]
 LDCM0215  AC10 HEK-293T C340(0.87); C352(1.05)  LDD0813  [6]
 LDCM0216  AC100 PaTu 8988t C352(0.89); C340(0.89); C346(0.89)  LDD1095  [6]
 LDCM0217  AC101 PaTu 8988t C352(0.89); C340(0.89); C346(0.89)  LDD1096  [6]
 LDCM0218  AC102 PaTu 8988t C352(1.20); C340(1.20); C346(1.20)  LDD1097  [6]
 LDCM0219  AC103 PaTu 8988t C352(0.67); C340(0.67); C346(0.67)  LDD1098  [6]
 LDCM0220  AC104 PaTu 8988t C352(1.15); C340(1.15); C346(1.15)  LDD1099  [6]
 LDCM0221  AC105 PaTu 8988t C352(0.93); C340(0.93); C346(0.93)  LDD1100  [6]
 LDCM0222  AC106 PaTu 8988t C352(0.89); C340(0.89); C346(0.89)  LDD1101  [6]
 LDCM0223  AC107 PaTu 8988t C352(1.35); C340(1.35); C346(1.35)  LDD1102  [6]
 LDCM0224  AC108 PaTu 8988t C352(0.79); C340(0.79); C346(0.79)  LDD1103  [6]
 LDCM0225  AC109 PaTu 8988t C352(0.90); C340(0.90); C346(0.90)  LDD1104  [6]
 LDCM0226  AC11 HEK-293T C340(0.93); C352(1.05)  LDD0824  [6]
 LDCM0227  AC110 PaTu 8988t C352(0.84); C340(0.84); C346(0.84)  LDD1106  [6]
 LDCM0228  AC111 PaTu 8988t C352(0.86); C340(0.86); C346(0.86)  LDD1107  [6]
 LDCM0229  AC112 PaTu 8988t C352(1.02); C340(1.02); C346(1.02)  LDD1108  [6]
 LDCM0237  AC12 HEK-293T C340(0.98); C352(1.01)  LDD0835  [6]
 LDCM0259  AC14 HEK-293T C340(1.32); C352(1.04)  LDD0857  [6]
 LDCM0263  AC143 HEK-293T C352(1.11)  LDD0861  [6]
 LDCM0264  AC144 HEK-293T C352(1.31)  LDD0862  [6]
 LDCM0265  AC145 HEK-293T C352(1.37)  LDD0863  [6]
 LDCM0266  AC146 HEK-293T C352(1.47)  LDD0864  [6]
 LDCM0267  AC147 HEK-293T C352(1.60)  LDD0865  [6]
 LDCM0268  AC148 HEK-293T C352(2.04)  LDD0866  [6]
 LDCM0269  AC149 HEK-293T C352(1.18)  LDD0867  [6]
 LDCM0270  AC15 HEK-293T C340(1.14); C352(1.21)  LDD0868  [6]
 LDCM0271  AC150 HEK-293T C352(1.32)  LDD0869  [6]
 LDCM0272  AC151 HEK-293T C352(1.35)  LDD0870  [6]
 LDCM0273  AC152 HEK-293T C352(1.26)  LDD0871  [6]
 LDCM0274  AC153 HEK-293T C352(1.35)  LDD0872  [6]
 LDCM0621  AC154 HEK-293T C352(1.13)  LDD2162  [6]
 LDCM0622  AC155 HEK-293T C352(1.34)  LDD2163  [6]
 LDCM0623  AC156 HEK-293T C352(1.64)  LDD2164  [6]
 LDCM0624  AC157 HEK-293T C352(2.16)  LDD2165  [6]
 LDCM0276  AC17 HEK-293T C352(0.97)  LDD0874  [6]
 LDCM0277  AC18 HEK-293T C352(0.94)  LDD0875  [6]
 LDCM0278  AC19 HEK-293T C352(0.92)  LDD0876  [6]
 LDCM0279  AC2 HEK-293T C340(1.26); C352(1.12)  LDD0877  [6]
 LDCM0280  AC20 HEK-293T C352(0.89)  LDD0878  [6]
 LDCM0281  AC21 HEK-293T C352(0.99)  LDD0879  [6]
 LDCM0282  AC22 HEK-293T C352(0.88)  LDD0880  [6]
 LDCM0283  AC23 HEK-293T C352(1.07)  LDD0881  [6]
 LDCM0284  AC24 HEK-293T C352(0.85)  LDD0882  [6]
 LDCM0285  AC25 HEK-293T C352(0.77)  LDD0883  [6]
 LDCM0286  AC26 HEK-293T C352(0.81)  LDD0884  [6]
 LDCM0287  AC27 HEK-293T C352(0.91)  LDD0885  [6]
 LDCM0288  AC28 HEK-293T C352(0.83)  LDD0886  [6]
 LDCM0289  AC29 HEK-293T C352(0.86)  LDD0887  [6]
 LDCM0290  AC3 HEK-293T C340(0.92); C352(1.12)  LDD0888  [6]
 LDCM0291  AC30 HEK-293T C352(0.83)  LDD0889  [6]
 LDCM0292  AC31 HEK-293T C352(0.72)  LDD0890  [6]
 LDCM0293  AC32 HEK-293T C352(0.83)  LDD0891  [6]
 LDCM0294  AC33 HEK-293T C352(0.80)  LDD0892  [6]
 LDCM0295  AC34 HEK-293T C352(0.74)  LDD0893  [6]
 LDCM0296  AC35 HEK-293T C352(1.23)  LDD0894  [6]
 LDCM0297  AC36 HEK-293T C352(1.05)  LDD0895  [6]
 LDCM0298  AC37 HEK-293T C352(1.16)  LDD0896  [6]
 LDCM0299  AC38 HEK-293T C352(1.18)  LDD0897  [6]
 LDCM0300  AC39 HEK-293T C352(1.01)  LDD0898  [6]
 LDCM0301  AC4 HEK-293T C340(1.48); C352(1.11)  LDD0899  [6]
 LDCM0302  AC40 HEK-293T C352(1.05)  LDD0900  [6]
 LDCM0303  AC41 HEK-293T C352(1.14)  LDD0901  [6]
 LDCM0304  AC42 HEK-293T C352(1.11)  LDD0902  [6]
 LDCM0305  AC43 HEK-293T C352(1.14)  LDD0903  [6]
 LDCM0306  AC44 HEK-293T C352(1.04)  LDD0904  [6]
 LDCM0307  AC45 HEK-293T C352(1.01)  LDD0905  [6]
 LDCM0308  AC46 HEK-293T C340(1.22); C352(1.04)  LDD0906  [6]
 LDCM0309  AC47 HEK-293T C340(1.28); C352(1.25)  LDD0907  [6]
 LDCM0310  AC48 HEK-293T C340(0.87); C352(1.09)  LDD0908  [6]
 LDCM0311  AC49 HEK-293T C340(1.27); C352(1.01)  LDD0909  [6]
 LDCM0312  AC5 HEK-293T C340(1.47); C352(1.02)  LDD0910  [6]
 LDCM0313  AC50 HEK-293T C340(1.08); C352(1.06)  LDD0911  [6]
 LDCM0314  AC51 HEK-293T C340(1.14); C352(1.09)  LDD0912  [6]
 LDCM0315  AC52 HEK-293T C340(1.38); C352(1.09)  LDD0913  [6]
 LDCM0316  AC53 HEK-293T C340(1.17); C352(0.99)  LDD0914  [6]
 LDCM0317  AC54 HEK-293T C340(1.09); C352(1.08)  LDD0915  [6]
 LDCM0318  AC55 HEK-293T C340(1.10); C352(1.08)  LDD0916  [6]
 LDCM0319  AC56 HEK-293T C340(0.88); C352(1.03)  LDD0917  [6]
 LDCM0320  AC57 HEK-293T C352(1.10)  LDD0918  [6]
 LDCM0321  AC58 HEK-293T C352(1.13)  LDD0919  [6]
 LDCM0322  AC59 HEK-293T C352(1.03)  LDD0920  [6]
 LDCM0323  AC6 HEK-293T C340(0.67); C352(0.76)  LDD0921  [6]
 LDCM0324  AC60 HEK-293T C352(0.99)  LDD0922  [6]
 LDCM0325  AC61 HEK-293T C352(1.15)  LDD0923  [6]
 LDCM0326  AC62 HEK-293T C352(1.16)  LDD0924  [6]
 LDCM0327  AC63 HEK-293T C352(1.12)  LDD0925  [6]
 LDCM0328  AC64 HEK-293T C352(1.03)  LDD0926  [6]
 LDCM0329  AC65 HEK-293T C352(1.13)  LDD0927  [6]
 LDCM0330  AC66 HEK-293T C352(1.09)  LDD0928  [6]
 LDCM0331  AC67 HEK-293T C352(1.05)  LDD0929  [6]
 LDCM0332  AC68 HEK-293T C352(0.94)  LDD0930  [6]
 LDCM0333  AC69 HEK-293T C352(1.00)  LDD0931  [6]
 LDCM0334  AC7 HEK-293T C340(0.77); C352(0.93)  LDD0932  [6]
 LDCM0335  AC70 HEK-293T C352(1.09)  LDD0933  [6]
 LDCM0336  AC71 HEK-293T C352(1.07)  LDD0934  [6]
 LDCM0337  AC72 HEK-293T C352(1.17)  LDD0935  [6]
 LDCM0338  AC73 HEK-293T C352(1.01)  LDD0936  [6]
 LDCM0339  AC74 HEK-293T C352(1.05)  LDD0937  [6]
 LDCM0340  AC75 HEK-293T C352(1.03)  LDD0938  [6]
 LDCM0341  AC76 HEK-293T C352(1.22)  LDD0939  [6]
 LDCM0342  AC77 HEK-293T C352(1.16)  LDD0940  [6]
 LDCM0343  AC78 HEK-293T C352(1.10)  LDD0941  [6]
 LDCM0344  AC79 HEK-293T C352(1.06)  LDD0942  [6]
 LDCM0345  AC8 HEK-293T C340(0.85); C352(0.98)  LDD0943  [6]
 LDCM0346  AC80 HEK-293T C352(1.06)  LDD0944  [6]
 LDCM0347  AC81 HEK-293T C352(1.08)  LDD0945  [6]
 LDCM0348  AC82 HEK-293T C352(1.16)  LDD0946  [6]
 LDCM0349  AC83 HEK-293T C352(0.90)  LDD0947  [6]
 LDCM0350  AC84 HEK-293T C352(0.89)  LDD0948  [6]
 LDCM0351  AC85 HEK-293T C352(0.85)  LDD0949  [6]
 LDCM0352  AC86 HEK-293T C352(0.88)  LDD0950  [6]
 LDCM0353  AC87 HEK-293T C352(0.88)  LDD0951  [6]
 LDCM0354  AC88 HEK-293T C352(0.89)  LDD0952  [6]
 LDCM0355  AC89 HEK-293T C352(1.00)  LDD0953  [6]
 LDCM0357  AC90 HEK-293T C352(0.94)  LDD0955  [6]
 LDCM0358  AC91 HEK-293T C352(0.96)  LDD0956  [6]
 LDCM0359  AC92 HEK-293T C352(0.77)  LDD0957  [6]
 LDCM0360  AC93 HEK-293T C352(0.91)  LDD0958  [6]
 LDCM0361  AC94 HEK-293T C352(0.96)  LDD0959  [6]
 LDCM0362  AC95 HEK-293T C352(0.89)  LDD0960  [6]
 LDCM0363  AC96 HEK-293T C352(0.90)  LDD0961  [6]
 LDCM0364  AC97 HEK-293T C352(1.11)  LDD0962  [6]
 LDCM0365  AC98 PaTu 8988t C352(0.80); C340(0.80); C346(0.80)  LDD1244  [6]
 LDCM0366  AC99 PaTu 8988t C352(1.23); C340(1.23); C346(1.23)  LDD1245  [6]
 LDCM0248  AKOS034007472 HEK-293T C340(1.22); C352(1.12)  LDD0846  [6]
 LDCM0356  AKOS034007680 HEK-293T C340(0.85); C352(1.15)  LDD0954  [6]
 LDCM0275  AKOS034007705 HEK-293T C340(1.27); C352(1.07)  LDD0873  [6]
 LDCM0367  CL1 PaTu 8988t C352(0.88); C340(0.88); C346(0.88)  LDD1246  [6]
 LDCM0368  CL10 PaTu 8988t C352(0.74); C340(0.74); C346(0.74)  LDD1247  [6]
 LDCM0369  CL100 HEK-293T C340(1.15); C352(1.11)  LDD0967  [6]
 LDCM0370  CL101 HEK-293T C340(0.79); C352(0.88)  LDD0968  [6]
 LDCM0371  CL102 HEK-293T C340(0.74); C352(0.95)  LDD0969  [6]
 LDCM0372  CL103 HEK-293T C340(0.77); C352(1.02)  LDD0970  [6]
 LDCM0373  CL104 HEK-293T C340(0.94); C352(0.97)  LDD0971  [6]
 LDCM0374  CL105 HEK-293T C352(0.80)  LDD0972  [6]
 LDCM0375  CL106 HEK-293T C352(0.91)  LDD0973  [6]
 LDCM0376  CL107 HEK-293T C352(0.85)  LDD0974  [6]
 LDCM0377  CL108 HEK-293T C352(0.81)  LDD0975  [6]
 LDCM0378  CL109 HEK-293T C352(0.95)  LDD0976  [6]
 LDCM0379  CL11 PaTu 8988t C352(1.01); C340(1.01); C346(1.01)  LDD1258  [6]
 LDCM0380  CL110 HEK-293T C352(0.89)  LDD0978  [6]
 LDCM0381  CL111 HEK-293T C352(0.80)  LDD0979  [6]
 LDCM0382  CL112 HEK-293T C352(0.81)  LDD0980  [6]
 LDCM0383  CL113 HEK-293T C352(0.87)  LDD0981  [6]
 LDCM0384  CL114 HEK-293T C352(0.88)  LDD0982  [6]
 LDCM0385  CL115 HEK-293T C352(0.77)  LDD0983  [6]
 LDCM0386  CL116 HEK-293T C352(0.79)  LDD0984  [6]
 LDCM0387  CL117 HEK-293T C352(1.14)  LDD0985  [6]
 LDCM0388  CL118 HEK-293T C352(1.01)  LDD0986  [6]
 LDCM0389  CL119 HEK-293T C352(0.96)  LDD0987  [6]
 LDCM0390  CL12 PaTu 8988t C352(0.72); C340(0.72); C346(0.72)  LDD1269  [6]
 LDCM0391  CL120 HEK-293T C352(1.05)  LDD0989  [6]
 LDCM0392  CL121 HEK-293T C340(1.20); C352(0.97)  LDD0990  [6]
 LDCM0393  CL122 HEK-293T C340(1.14); C352(1.01)  LDD0991  [6]
 LDCM0394  CL123 HEK-293T C340(0.95); C352(1.01)  LDD0992  [6]
 LDCM0395  CL124 HEK-293T C340(1.17); C352(0.90)  LDD0993  [6]
 LDCM0396  CL125 HEK-293T C352(1.07)  LDD0994  [6]
 LDCM0397  CL126 HEK-293T C352(1.21)  LDD0995  [6]
 LDCM0398  CL127 HEK-293T C352(1.11)  LDD0996  [6]
 LDCM0399  CL128 HEK-293T C352(1.14)  LDD0997  [6]
 LDCM0400  CL13 PaTu 8988t C352(0.88); C340(0.88); C346(0.88)  LDD1279  [6]
 LDCM0401  CL14 PaTu 8988t C352(1.07); C340(1.07); C346(1.07)  LDD1280  [6]
 LDCM0402  CL15 PaTu 8988t C352(0.74); C340(0.74); C346(0.74)  LDD1281  [6]
 LDCM0403  CL16 HEK-293T C352(0.85)  LDD1001  [6]
 LDCM0404  CL17 HEK-293T C352(0.98)  LDD1002  [6]
 LDCM0405  CL18 HEK-293T C352(1.06)  LDD1003  [6]
 LDCM0406  CL19 HEK-293T C352(1.09)  LDD1004  [6]
 LDCM0407  CL2 PaTu 8988t C352(0.82); C340(0.82); C346(0.82)  LDD1286  [6]
 LDCM0408  CL20 HEK-293T C352(1.02)  LDD1006  [6]
 LDCM0409  CL21 HEK-293T C352(1.19)  LDD1007  [6]
 LDCM0410  CL22 HEK-293T C352(0.94)  LDD1008  [6]
 LDCM0411  CL23 HEK-293T C352(1.03)  LDD1009  [6]
 LDCM0412  CL24 HEK-293T C352(1.00)  LDD1010  [6]
 LDCM0413  CL25 HEK-293T C352(1.08)  LDD1011  [6]
 LDCM0414  CL26 HEK-293T C352(1.08)  LDD1012  [6]
 LDCM0415  CL27 HEK-293T C352(1.11)  LDD1013  [6]
 LDCM0416  CL28 HEK-293T C352(1.12)  LDD1014  [6]
 LDCM0417  CL29 HEK-293T C352(1.11)  LDD1015  [6]
 LDCM0418  CL3 PaTu 8988t C352(0.75); C340(0.75); C346(0.75)  LDD1297  [6]
 LDCM0419  CL30 HEK-293T C352(1.09)  LDD1017  [6]
 LDCM0420  CL31 HEK-293T C352(0.77)  LDD1018  [6]
 LDCM0421  CL32 HEK-293T C352(0.89)  LDD1019  [6]
 LDCM0422  CL33 HEK-293T C352(0.82)  LDD1020  [6]
 LDCM0423  CL34 HEK-293T C352(0.90)  LDD1021  [6]
 LDCM0424  CL35 HEK-293T C352(0.97)  LDD1022  [6]
 LDCM0425  CL36 HEK-293T C352(1.16)  LDD1023  [6]
 LDCM0426  CL37 HEK-293T C352(0.89)  LDD1024  [6]
 LDCM0428  CL39 HEK-293T C352(1.25)  LDD1026  [6]
 LDCM0429  CL4 PaTu 8988t C352(0.61); C340(0.61); C346(0.61)  LDD1308  [6]
 LDCM0430  CL40 HEK-293T C352(1.04)  LDD1028  [6]
 LDCM0431  CL41 HEK-293T C352(1.14)  LDD1029  [6]
 LDCM0432  CL42 HEK-293T C352(1.33)  LDD1030  [6]
 LDCM0433  CL43 HEK-293T C352(1.35)  LDD1031  [6]
 LDCM0434  CL44 HEK-293T C352(1.04)  LDD1032  [6]
 LDCM0435  CL45 HEK-293T C352(1.16)  LDD1033  [6]
 LDCM0436  CL46 HEK-293T C352(0.85)  LDD1034  [6]
 LDCM0437  CL47 HEK-293T C352(0.94)  LDD1035  [6]
 LDCM0438  CL48 HEK-293T C352(0.94)  LDD1036  [6]
 LDCM0439  CL49 HEK-293T C352(1.05)  LDD1037  [6]
 LDCM0440  CL5 PaTu 8988t C352(0.84); C340(0.84); C346(0.84)  LDD1319  [6]
 LDCM0441  CL50 HEK-293T C352(1.26)  LDD1039  [6]
 LDCM0442  CL51 HEK-293T C352(1.17)  LDD1040  [6]
 LDCM0443  CL52 HEK-293T C352(1.05)  LDD1041  [6]
 LDCM0444  CL53 HEK-293T C352(1.01)  LDD1042  [6]
 LDCM0445  CL54 HEK-293T C352(1.18)  LDD1043  [6]
 LDCM0446  CL55 HEK-293T C352(0.94)  LDD1044  [6]
 LDCM0447  CL56 HEK-293T C352(1.00)  LDD1045  [6]
 LDCM0448  CL57 HEK-293T C352(0.89)  LDD1046  [6]
 LDCM0449  CL58 HEK-293T C352(1.16)  LDD1047  [6]
 LDCM0450  CL59 HEK-293T C352(1.12)  LDD1048  [6]
 LDCM0451  CL6 PaTu 8988t C352(0.92); C340(0.92); C346(0.92)  LDD1330  [6]
 LDCM0452  CL60 HEK-293T C352(1.37)  LDD1050  [6]
 LDCM0453  CL61 HEK-293T C340(0.39); C352(0.79)  LDD1051  [6]
 LDCM0454  CL62 HEK-293T C340(0.73); C352(0.91)  LDD1052  [6]
 LDCM0455  CL63 HEK-293T C340(0.54); C352(0.80)  LDD1053  [6]
 LDCM0456  CL64 HEK-293T C340(0.47); C352(0.80)  LDD1054  [6]
 LDCM0457  CL65 HEK-293T C340(0.58); C352(0.88)  LDD1055  [6]
 LDCM0458  CL66 HEK-293T C340(0.49); C352(0.93)  LDD1056  [6]
 LDCM0459  CL67 HEK-293T C340(0.68); C352(1.00)  LDD1057  [6]
 LDCM0460  CL68 HEK-293T C340(0.61); C352(1.19)  LDD1058  [6]
 LDCM0461  CL69 HEK-293T C340(0.82); C352(1.00)  LDD1059  [6]
 LDCM0462  CL7 PaTu 8988t C352(0.88); C340(0.88); C346(0.88)  LDD1341  [6]
 LDCM0463  CL70 HEK-293T C340(0.88); C352(1.15)  LDD1061  [6]
 LDCM0464  CL71 HEK-293T C340(0.74); C352(1.12)  LDD1062  [6]
 LDCM0465  CL72 HEK-293T C340(0.76); C352(0.85)  LDD1063  [6]
 LDCM0466  CL73 HEK-293T C340(0.78); C352(1.19)  LDD1064  [6]
 LDCM0467  CL74 HEK-293T C340(0.62); C352(1.40)  LDD1065  [6]
 LDCM0469  CL76 HEK-293T C352(0.86)  LDD1067  [6]
 LDCM0470  CL77 HEK-293T C352(0.92)  LDD1068  [6]
 LDCM0471  CL78 HEK-293T C352(0.68)  LDD1069  [6]
 LDCM0472  CL79 HEK-293T C352(0.67)  LDD1070  [6]
 LDCM0473  CL8 PaTu 8988t C352(0.74); C340(0.74); C346(0.74)  LDD1352  [6]
 LDCM0474  CL80 HEK-293T C352(0.93)  LDD1072  [6]
 LDCM0475  CL81 HEK-293T C352(0.94)  LDD1073  [6]
 LDCM0476  CL82 HEK-293T C352(1.07)  LDD1074  [6]
 LDCM0477  CL83 HEK-293T C352(0.99)  LDD1075  [6]
 LDCM0478  CL84 HEK-293T C352(0.71)  LDD1076  [6]
 LDCM0479  CL85 HEK-293T C352(0.82)  LDD1077  [6]
 LDCM0480  CL86 HEK-293T C352(0.76)  LDD1078  [6]
 LDCM0481  CL87 HEK-293T C352(0.82)  LDD1079  [6]
 LDCM0482  CL88 HEK-293T C352(0.97)  LDD1080  [6]
 LDCM0483  CL89 HEK-293T C352(0.83)  LDD1081  [6]
 LDCM0484  CL9 PaTu 8988t C352(0.92); C340(0.92); C346(0.92)  LDD1363  [6]
 LDCM0485  CL90 HEK-293T C352(0.86)  LDD1083  [6]
 LDCM0486  CL91 HEK-293T C340(0.97); C352(0.77)  LDD1084  [6]
 LDCM0487  CL92 HEK-293T C340(0.85); C352(0.90)  LDD1085  [6]
 LDCM0488  CL93 HEK-293T C340(0.67); C352(0.86)  LDD1086  [6]
 LDCM0489  CL94 HEK-293T C340(0.72); C352(0.81)  LDD1087  [6]
 LDCM0490  CL95 HEK-293T C340(0.98); C352(0.90)  LDD1088  [6]
 LDCM0491  CL96 HEK-293T C340(0.80); C352(0.83)  LDD1089  [6]
 LDCM0492  CL97 HEK-293T C340(0.67); C352(0.86)  LDD1090  [6]
 LDCM0493  CL98 HEK-293T C340(1.04); C352(0.97)  LDD1091  [6]
 LDCM0494  CL99 HEK-293T C340(1.04); C352(1.02)  LDD1092  [6]
 LDCM0495  E2913 HEK-293T C272(1.06); C100(0.95)  LDD1698  [7]
 LDCM0468  Fragment33 HEK-293T C340(0.92); C352(1.05)  LDD1066  [6]
 LDCM0427  Fragment51 HEK-293T C352(0.97)  LDD1025  [6]
 LDCM0022  KB02 AN3-CA C72(1.24)  LDD2264  [8]
 LDCM0023  KB03 Jurkat C100(28.51)  LDD0209  [3]
 LDCM0024  KB05 PaTu 8988t C72(2.91)  LDD3393  [8]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein BANP (BANP) BANP/SMAR1 family Q8N9N5
Lipid transferase CIDEB (CIDEB) CIDE family Q9UHD4

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
3 Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.
4 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
5 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
6 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
7 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
8 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840