Details of the Target

General Information of Target

Target ID LDTP08507
Target Name Coiled-coil domain-containing protein 50 (CCDC50)
Gene Name CCDC50
Gene ID 152137
Synonyms
C3orf6; Coiled-coil domain-containing protein 50; Protein Ymer
3D Structure
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2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAK
QLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKE
LQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIAR
KLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPK
TAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHK
GFHYKH
Target Bioclass
Other
Subcellular location
Cytoplasm
Function Involved in EGFR signaling.
Uniprot ID
Q8IVM0
Ensemble ID
ENST00000392455.9
HGNC ID
HGNC:18111

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 14 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
STPyne
 Probe Info  		K129(10.00); K294(10.00); K305(3.19)  LDD0277  [2]
DBIA
 Probe Info  		C85(0.67)  LDD3342  [3]
BTD
 Probe Info  		C85(0.95)  LDD2098  [4]
AHL-Pu-1
 Probe Info  		C85(5.48)  LDD0168  [5]
HHS-475
 Probe Info  		Y140(0.46); Y144(1.03); Y145(1.11)  LDD0264  [6]
5E-2FA
 Probe Info  		N.A.  LDD2235  [7]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [8]
IPM
 Probe Info  		N.A.  LDD0025  [9]
NAIA_4
 Probe Info  		N.A.  LDD2226  [10]
NAIA_5
 Probe Info  		N.A.  LDD2224  [10]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [11]
Acrolein
 Probe Info  		N.A.  LDD0217  [12]
HHS-465
 Probe Info  		N.A.  LDD2240  [13]
PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
VE-P
 Probe Info  		N.A.  LDD0396  [14]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C85(5.48)  LDD0168  [5]
 LDCM0215  AC10 HEK-293T C85(0.99)  LDD1508  [15]
 LDCM0226  AC11 HEK-293T C85(1.02)  LDD1509  [15]
 LDCM0237  AC12 HEK-293T C85(1.09)  LDD1510  [15]
 LDCM0259  AC14 HEK-293T C85(0.92)  LDD1512  [15]
 LDCM0270  AC15 HEK-293T C85(1.01)  LDD1513  [15]
 LDCM0277  AC18 HEK-293T C85(1.03)  LDD1516  [15]
 LDCM0278  AC19 HEK-293T C85(1.22)  LDD1517  [15]
 LDCM0279  AC2 HEK-293T C85(1.01)  LDD1518  [15]
 LDCM0280  AC20 HEK-293T C85(0.88)  LDD1519  [15]
 LDCM0281  AC21 HEK-293T C85(0.97)  LDD1520  [15]
 LDCM0282  AC22 HEK-293T C85(0.94)  LDD1521  [15]
 LDCM0283  AC23 HEK-293T C85(1.09)  LDD1522  [15]
 LDCM0284  AC24 HEK-293T C85(0.98)  LDD1523  [15]
 LDCM0286  AC26 HEK-293T C85(0.97)  LDD1525  [15]
 LDCM0287  AC27 HEK-293T C85(1.12)  LDD1526  [15]
 LDCM0288  AC28 HEK-293T C85(0.86)  LDD1527  [15]
 LDCM0289  AC29 HEK-293T C85(1.04)  LDD1528  [15]
 LDCM0290  AC3 HEK-293T C85(1.05)  LDD1529  [15]
 LDCM0291  AC30 HEK-293T C85(0.99)  LDD1530  [15]
 LDCM0292  AC31 HEK-293T C85(1.10)  LDD1531  [15]
 LDCM0293  AC32 HEK-293T C85(0.86)  LDD1532  [15]
 LDCM0295  AC34 HEK-293T C85(0.99)  LDD1534  [15]
 LDCM0296  AC35 HEK-293T C85(1.01)  LDD1535  [15]
 LDCM0297  AC36 HEK-293T C85(0.96)  LDD1536  [15]
 LDCM0298  AC37 HEK-293T C85(1.06)  LDD1537  [15]
 LDCM0299  AC38 HEK-293T C85(0.90)  LDD1538  [15]
 LDCM0300  AC39 HEK-293T C85(1.14)  LDD1539  [15]
 LDCM0301  AC4 HEK-293T C85(1.09)  LDD1540  [15]
 LDCM0302  AC40 HEK-293T C85(0.92)  LDD1541  [15]
 LDCM0304  AC42 HEK-293T C85(1.00)  LDD1543  [15]
 LDCM0305  AC43 HEK-293T C85(1.05)  LDD1544  [15]
 LDCM0306  AC44 HEK-293T C85(1.10)  LDD1545  [15]
 LDCM0307  AC45 HEK-293T C85(1.04)  LDD1546  [15]
 LDCM0308  AC46 HEK-293T C85(0.94)  LDD1547  [15]
 LDCM0309  AC47 HEK-293T C85(1.07)  LDD1548  [15]
 LDCM0310  AC48 HEK-293T C85(0.97)  LDD1549  [15]
 LDCM0312  AC5 HEK-293T C85(1.03)  LDD1551  [15]
 LDCM0313  AC50 HEK-293T C85(0.93)  LDD1552  [15]
 LDCM0314  AC51 HEK-293T C85(1.05)  LDD1553  [15]
 LDCM0315  AC52 HEK-293T C85(1.08)  LDD1554  [15]
 LDCM0316  AC53 HEK-293T C85(1.01)  LDD1555  [15]
 LDCM0317  AC54 HEK-293T C85(0.97)  LDD1556  [15]
 LDCM0318  AC55 HEK-293T C85(1.04)  LDD1557  [15]
 LDCM0319  AC56 HEK-293T C85(0.88)  LDD1558  [15]
 LDCM0321  AC58 HEK-293T C85(1.00)  LDD1560  [15]
 LDCM0322  AC59 HEK-293T C85(1.04)  LDD1561  [15]
 LDCM0323  AC6 HEK-293T C85(0.89)  LDD1562  [15]
 LDCM0324  AC60 HEK-293T C85(0.85)  LDD1563  [15]
 LDCM0325  AC61 HEK-293T C85(1.07)  LDD1564  [15]
 LDCM0326  AC62 HEK-293T C85(0.98)  LDD1565  [15]
 LDCM0327  AC63 HEK-293T C85(1.05)  LDD1566  [15]
 LDCM0328  AC64 HEK-293T C85(0.94)  LDD1567  [15]
 LDCM0334  AC7 HEK-293T C85(0.97)  LDD1568  [15]
 LDCM0345  AC8 HEK-293T C85(0.91)  LDD1569  [15]
 LDCM0248  AKOS034007472 HEK-293T C85(1.00)  LDD1511  [15]
 LDCM0275  AKOS034007705 HEK-293T C85(0.93)  LDD1514  [15]
 LDCM0156  Aniline NCI-H1299 14.17  LDD0403  [1]
 LDCM0630  CCW28-3 231MFP C85(2.39)  LDD2214  [16]
 LDCM0632  CL-Sc Hep-G2 C85(0.97)  LDD2227  [10]
 LDCM0367  CL1 HEK-293T C85(1.08)  LDD1571  [15]
 LDCM0368  CL10 HEK-293T C85(0.86)  LDD1572  [15]
 LDCM0369  CL100 HEK-293T C85(0.99)  LDD1573  [15]
 LDCM0370  CL101 HEK-293T C85(0.97)  LDD1574  [15]
 LDCM0371  CL102 HEK-293T C85(0.91)  LDD1575  [15]
 LDCM0372  CL103 HEK-293T C85(1.00)  LDD1576  [15]
 LDCM0373  CL104 HEK-293T C85(0.85)  LDD1577  [15]
 LDCM0374  CL105 HEK-293T C85(1.00)  LDD1578  [15]
 LDCM0375  CL106 HEK-293T C85(0.90)  LDD1579  [15]
 LDCM0376  CL107 HEK-293T C85(0.97)  LDD1580  [15]
 LDCM0377  CL108 HEK-293T C85(0.93)  LDD1581  [15]
 LDCM0378  CL109 HEK-293T C85(1.07)  LDD1582  [15]
 LDCM0379  CL11 HEK-293T C85(0.96)  LDD1583  [15]
 LDCM0380  CL110 HEK-293T C85(0.89)  LDD1584  [15]
 LDCM0381  CL111 HEK-293T C85(0.97)  LDD1585  [15]
 LDCM0382  CL112 HEK-293T C85(0.98)  LDD1586  [15]
 LDCM0383  CL113 HEK-293T C85(1.02)  LDD1587  [15]
 LDCM0384  CL114 HEK-293T C85(1.05)  LDD1588  [15]
 LDCM0385  CL115 HEK-293T C85(1.05)  LDD1589  [15]
 LDCM0386  CL116 HEK-293T C85(1.00)  LDD1590  [15]
 LDCM0387  CL117 HEK-293T C85(1.03)  LDD1591  [15]
 LDCM0388  CL118 HEK-293T C85(1.02)  LDD1592  [15]
 LDCM0389  CL119 HEK-293T C85(0.96)  LDD1593  [15]
 LDCM0390  CL12 HEK-293T C85(0.91)  LDD1594  [15]
 LDCM0391  CL120 HEK-293T C85(0.85)  LDD1595  [15]
 LDCM0392  CL121 HEK-293T C85(1.00)  LDD1596  [15]
 LDCM0393  CL122 HEK-293T C85(1.07)  LDD1597  [15]
 LDCM0394  CL123 HEK-293T C85(0.98)  LDD1598  [15]
 LDCM0395  CL124 HEK-293T C85(0.91)  LDD1599  [15]
 LDCM0396  CL125 HEK-293T C85(1.00)  LDD1600  [15]
 LDCM0397  CL126 HEK-293T C85(0.94)  LDD1601  [15]
 LDCM0398  CL127 HEK-293T C85(1.06)  LDD1602  [15]
 LDCM0399  CL128 HEK-293T C85(1.03)  LDD1603  [15]
 LDCM0400  CL13 HEK-293T C85(1.07)  LDD1604  [15]
 LDCM0401  CL14 HEK-293T C85(0.93)  LDD1605  [15]
 LDCM0402  CL15 HEK-293T C85(0.95)  LDD1606  [15]
 LDCM0403  CL16 HEK-293T C85(0.84)  LDD1607  [15]
 LDCM0405  CL18 HEK-293T C85(1.11)  LDD1609  [15]
 LDCM0406  CL19 HEK-293T C85(1.17)  LDD1610  [15]
 LDCM0407  CL2 HEK-293T C85(0.97)  LDD1611  [15]
 LDCM0408  CL20 HEK-293T C85(0.96)  LDD1612  [15]
 LDCM0409  CL21 HEK-293T C85(1.02)  LDD1613  [15]
 LDCM0410  CL22 HEK-293T C85(1.02)  LDD1614  [15]
 LDCM0411  CL23 HEK-293T C85(1.08)  LDD1615  [15]
 LDCM0412  CL24 HEK-293T C85(0.85)  LDD1616  [15]
 LDCM0413  CL25 HEK-293T C85(0.95)  LDD1617  [15]
 LDCM0414  CL26 HEK-293T C85(0.94)  LDD1618  [15]
 LDCM0415  CL27 HEK-293T C85(1.00)  LDD1619  [15]
 LDCM0416  CL28 HEK-293T C85(0.95)  LDD1620  [15]
 LDCM0418  CL3 HEK-293T C85(1.11)  LDD1622  [15]
 LDCM0419  CL30 HEK-293T C85(1.04)  LDD1623  [15]
 LDCM0420  CL31 HEK-293T C85(1.04)  LDD1624  [15]
 LDCM0421  CL32 HEK-293T C85(0.86)  LDD1625  [15]
 LDCM0422  CL33 HEK-293T C85(0.93)  LDD1626  [15]
 LDCM0423  CL34 HEK-293T C85(1.02)  LDD1627  [15]
 LDCM0424  CL35 HEK-293T C85(1.05)  LDD1628  [15]
 LDCM0425  CL36 HEK-293T C85(0.92)  LDD1629  [15]
 LDCM0426  CL37 HEK-293T C85(0.95)  LDD1630  [15]
 LDCM0428  CL39 HEK-293T C85(1.16)  LDD1632  [15]
 LDCM0429  CL4 HEK-293T C85(0.88)  LDD1633  [15]
 LDCM0430  CL40 HEK-293T C85(1.01)  LDD1634  [15]
 LDCM0432  CL42 HEK-293T C85(0.94)  LDD1636  [15]
 LDCM0433  CL43 HEK-293T C85(1.02)  LDD1637  [15]
 LDCM0434  CL44 HEK-293T C85(1.05)  LDD1638  [15]
 LDCM0435  CL45 HEK-293T C85(1.09)  LDD1639  [15]
 LDCM0436  CL46 HEK-293T C85(1.06)  LDD1640  [15]
 LDCM0437  CL47 HEK-293T C85(1.03)  LDD1641  [15]
 LDCM0438  CL48 HEK-293T C85(0.92)  LDD1642  [15]
 LDCM0439  CL49 HEK-293T C85(1.05)  LDD1643  [15]
 LDCM0441  CL50 HEK-293T C85(0.97)  LDD1645  [15]
 LDCM0443  CL52 HEK-293T C85(0.98)  LDD1646  [15]
 LDCM0445  CL54 HEK-293T C85(1.03)  LDD1648  [15]
 LDCM0446  CL55 HEK-293T C85(1.09)  LDD1649  [15]
 LDCM0447  CL56 HEK-293T C85(1.02)  LDD1650  [15]
 LDCM0448  CL57 HEK-293T C85(1.00)  LDD1651  [15]
 LDCM0449  CL58 HEK-293T C85(0.94)  LDD1652  [15]
 LDCM0450  CL59 HEK-293T C85(1.14)  LDD1653  [15]
 LDCM0451  CL6 HEK-293T C85(0.99)  LDD1654  [15]
 LDCM0452  CL60 HEK-293T C85(0.88)  LDD1655  [15]
 LDCM0453  CL61 HEK-293T C85(1.09)  LDD1656  [15]
 LDCM0454  CL62 HEK-293T C85(0.99)  LDD1657  [15]
 LDCM0455  CL63 HEK-293T C85(0.96)  LDD1658  [15]
 LDCM0456  CL64 HEK-293T C85(0.87)  LDD1659  [15]
 LDCM0458  CL66 HEK-293T C85(0.99)  LDD1661  [15]
 LDCM0459  CL67 HEK-293T C85(1.11)  LDD1662  [15]
 LDCM0460  CL68 HEK-293T C85(0.92)  LDD1663  [15]
 LDCM0461  CL69 HEK-293T C85(1.07)  LDD1664  [15]
 LDCM0462  CL7 HEK-293T C85(1.08)  LDD1665  [15]
 LDCM0463  CL70 HEK-293T C85(0.96)  LDD1666  [15]
 LDCM0464  CL71 HEK-293T C85(1.03)  LDD1667  [15]
 LDCM0465  CL72 HEK-293T C85(0.93)  LDD1668  [15]
 LDCM0466  CL73 HEK-293T C85(0.87)  LDD1669  [15]
 LDCM0467  CL74 HEK-293T C85(0.93)  LDD1670  [15]
 LDCM0469  CL76 HEK-293T C85(0.94)  LDD1672  [15]
 LDCM0471  CL78 HEK-293T C85(1.00)  LDD1674  [15]
 LDCM0472  CL79 HEK-293T C85(1.02)  LDD1675  [15]
 LDCM0473  CL8 HEK-293T C85(0.81)  LDD1676  [15]
 LDCM0474  CL80 HEK-293T C85(1.00)  LDD1677  [15]
 LDCM0475  CL81 HEK-293T C85(1.08)  LDD1678  [15]
 LDCM0476  CL82 HEK-293T C85(0.90)  LDD1679  [15]
 LDCM0477  CL83 HEK-293T C85(1.01)  LDD1680  [15]
 LDCM0478  CL84 HEK-293T C85(0.86)  LDD1681  [15]
 LDCM0479  CL85 HEK-293T C85(1.17)  LDD1682  [15]
 LDCM0480  CL86 HEK-293T C85(0.98)  LDD1683  [15]
 LDCM0481  CL87 HEK-293T C85(1.00)  LDD1684  [15]
 LDCM0482  CL88 HEK-293T C85(0.85)  LDD1685  [15]
 LDCM0484  CL9 HEK-293T C85(1.01)  LDD1687  [15]
 LDCM0485  CL90 HEK-293T C85(0.86)  LDD1688  [15]
 LDCM0486  CL91 HEK-293T C85(1.14)  LDD1689  [15]
 LDCM0487  CL92 HEK-293T C85(1.05)  LDD1690  [15]
 LDCM0488  CL93 HEK-293T C85(1.00)  LDD1691  [15]
 LDCM0489  CL94 HEK-293T C85(0.97)  LDD1692  [15]
 LDCM0490  CL95 HEK-293T C85(0.92)  LDD1693  [15]
 LDCM0491  CL96 HEK-293T C85(0.93)  LDD1694  [15]
 LDCM0492  CL97 HEK-293T C85(0.98)  LDD1695  [15]
 LDCM0493  CL98 HEK-293T C85(0.99)  LDD1696  [15]
 LDCM0494  CL99 HEK-293T C85(1.01)  LDD1697  [15]
 LDCM0495  E2913 HEK-293T C85(1.11)  LDD1698  [15]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C85(0.78)  LDD1702  [4]
 LDCM0468  Fragment33 HEK-293T C85(1.03)  LDD1671  [15]
 LDCM0427  Fragment51 HEK-293T C85(1.01)  LDD1631  [15]
 LDCM0116  HHS-0101 DM93 Y140(0.46); Y144(1.03); Y145(1.11)  LDD0264  [6]
 LDCM0117  HHS-0201 DM93 Y145(0.54); Y140(0.96); Y144(1.07)  LDD0265  [6]
 LDCM0118  HHS-0301 DM93 Y140(0.16); Y145(0.57); Y144(0.95)  LDD0266  [6]
 LDCM0119  HHS-0401 DM93 Y140(0.55); Y145(0.86); Y144(1.18)  LDD0267  [6]
 LDCM0120  HHS-0701 DM93 Y145(0.90); Y144(1.12)  LDD0268  [6]
 LDCM0022  KB02 HEK-293T C85(1.03)  LDD1492  [15]
 LDCM0023  KB03 HEK-293T C85(1.00)  LDD1497  [15]
 LDCM0024  KB05 NCI-H1155 C85(0.67)  LDD3342  [3]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C85(0.95)  LDD2098  [4]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C85(0.85)  LDD2120  [4]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C85(0.94)  LDD2126  [4]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C85(0.83)  LDD2141  [4]
 LDCM0131  RA190 MM1.R C85(1.30)  LDD0304  [17]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
OTU domain-containing protein 7B (OTUD7B) Peptidase C64 family Q6GQQ9
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) TKL Ser/Thr protein kinase family Q13546
E3 ubiquitin-protein ligase RNF8 (RNF8) RNF8 family O76064
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Arrestin domain-containing protein 3 (ARRDC3) Arrestin family Q96B67
Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Endophilin-A2 (SH3GL1) Endophilin family Q99961
Polyubiquitin-B (UBB) Ubiquitin family P0CG47

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
3 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
4 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
5 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
6 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
7 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
8 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
9 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
10 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
11 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
12 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
13 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010
14 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
15 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
16 Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.
17 Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.