Details of the Target

General Information of Target

Target ID LDTP08189
Target Name Protein hinderin (KIAA1328)
Gene Name KIAA1328
Gene ID 57536
Synonyms
Protein hinderin
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT
DASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE
ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL
SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI
AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP
TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK
QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGW
LLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKD
ASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWN
HGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI
Target Bioclass
Other
Function Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes.
Uniprot ID
Q86T90
Ensemble ID
ENST00000280020.10
HGNC ID
HGNC:29248

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
A2058 SNV: p.S170L .
EGI1 Deletion: p.I106KfsTer6 .
J82 SNV: p.R18W .
JURKAT SNV: p.T282I .
KYM1 SNV: p.A14V .
MCC13 SNV: p.P532L .
MEWO SNV: p.K554R .
NCIH716 SNV: p.K394T .
RH30 SNV: p.H541P .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K53(5.56)  LDD0277  [1]
DBIA
 Probe Info  		C82(0.53)  LDD0814  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0215  AC10 HEK-293T C467(0.86)  LDD1508  [3]
 LDCM0216  AC100 HEK-293T C82(0.53)  LDD0814  [2]
 LDCM0217  AC101 HEK-293T C82(0.65)  LDD0815  [2]
 LDCM0218  AC102 HEK-293T C82(0.59)  LDD0816  [2]
 LDCM0219  AC103 HEK-293T C82(0.54)  LDD0817  [2]
 LDCM0220  AC104 HEK-293T C82(0.59)  LDD0818  [2]
 LDCM0221  AC105 HEK-293T C82(1.47)  LDD0819  [2]
 LDCM0222  AC106 HEK-293T C82(1.63)  LDD0820  [2]
 LDCM0223  AC107 HEK-293T C82(0.53)  LDD0821  [2]
 LDCM0224  AC108 HEK-293T C82(1.43)  LDD0822  [2]
 LDCM0225  AC109 HEK-293T C82(0.97)  LDD0823  [2]
 LDCM0227  AC110 HEK-293T C82(0.53)  LDD0825  [2]
 LDCM0228  AC111 HEK-293T C82(0.75)  LDD0826  [2]
 LDCM0229  AC112 HEK-293T C82(0.58)  LDD0827  [2]
 LDCM0230  AC113 HEK-293T C82(1.09)  LDD0828  [2]
 LDCM0231  AC114 HEK-293T C82(0.84)  LDD0829  [2]
 LDCM0232  AC115 HEK-293T C82(0.68)  LDD0830  [2]
 LDCM0233  AC116 HEK-293T C82(0.80)  LDD0831  [2]
 LDCM0234  AC117 HEK-293T C82(0.44)  LDD0832  [2]
 LDCM0235  AC118 HEK-293T C82(0.39)  LDD0833  [2]
 LDCM0236  AC119 HEK-293T C82(0.36)  LDD0834  [2]
 LDCM0238  AC120 HEK-293T C82(0.55)  LDD0836  [2]
 LDCM0239  AC121 HEK-293T C82(0.35)  LDD0837  [2]
 LDCM0240  AC122 HEK-293T C82(0.38)  LDD0838  [2]
 LDCM0241  AC123 HEK-293T C82(0.35)  LDD0839  [2]
 LDCM0242  AC124 HEK-293T C82(0.38)  LDD0840  [2]
 LDCM0243  AC125 HEK-293T C82(0.33)  LDD0841  [2]
 LDCM0244  AC126 HEK-293T C82(0.44)  LDD0842  [2]
 LDCM0245  AC127 HEK-293T C82(0.44)  LDD0843  [2]
 LDCM0246  AC128 HEK-293T C82(1.58)  LDD0844  [2]
 LDCM0247  AC129 HEK-293T C82(0.43)  LDD0845  [2]
 LDCM0249  AC130 HEK-293T C82(0.43)  LDD0847  [2]
 LDCM0250  AC131 HEK-293T C82(0.94)  LDD0848  [2]
 LDCM0251  AC132 HEK-293T C82(0.55)  LDD0849  [2]
 LDCM0252  AC133 HEK-293T C82(0.33)  LDD0850  [2]
 LDCM0253  AC134 HEK-293T C82(0.34)  LDD0851  [2]
 LDCM0254  AC135 HEK-293T C82(0.45)  LDD0852  [2]
 LDCM0255  AC136 HEK-293T C82(0.47)  LDD0853  [2]
 LDCM0256  AC137 HEK-293T C82(0.37)  LDD0854  [2]
 LDCM0257  AC138 HEK-293T C82(0.38)  LDD0855  [2]
 LDCM0258  AC139 HEK-293T C82(0.41)  LDD0856  [2]
 LDCM0259  AC14 HEK-293T C467(1.03)  LDD1512  [3]
 LDCM0260  AC140 HEK-293T C82(0.32)  LDD0858  [2]
 LDCM0261  AC141 HEK-293T C82(0.33)  LDD0859  [2]
 LDCM0262  AC142 HEK-293T C82(0.34)  LDD0860  [2]
 LDCM0270  AC15 HEK-293T C467(1.00)  LDD1513  [3]
 LDCM0277  AC18 HEK-293T C467(0.86)  LDD1516  [3]
 LDCM0279  AC2 HEK-293T C467(0.84)  LDD1518  [3]
 LDCM0281  AC21 HEK-293T C467(1.00); C95(1.04)  LDD1520  [3]
 LDCM0282  AC22 HEK-293T C467(0.93)  LDD1521  [3]
 LDCM0283  AC23 HEK-293T C467(0.98)  LDD1522  [3]
 LDCM0284  AC24 HEK-293T C467(0.95); C95(1.10); C335(0.98)  LDD1523  [3]
 LDCM0286  AC26 HEK-293T C467(0.88)  LDD1525  [3]
 LDCM0289  AC29 HEK-293T C467(1.00); C95(1.00)  LDD1528  [3]
 LDCM0291  AC30 HEK-293T C467(1.07)  LDD1530  [3]
 LDCM0292  AC31 HEK-293T C467(0.99)  LDD1531  [3]
 LDCM0293  AC32 HEK-293T C467(0.96); C95(1.03); C335(0.96)  LDD1532  [3]
 LDCM0295  AC34 HEK-293T C467(0.91)  LDD1534  [3]
 LDCM0296  AC35 PaTu 8988t C82(1.41)  LDD1175  [2]
 LDCM0297  AC36 PaTu 8988t C82(1.20)  LDD1176  [2]
 LDCM0298  AC37 PaTu 8988t C82(0.86)  LDD1177  [2]
 LDCM0299  AC38 PaTu 8988t C82(1.17)  LDD1178  [2]
 LDCM0300  AC39 PaTu 8988t C82(1.52)  LDD1179  [2]
 LDCM0302  AC40 PaTu 8988t C82(1.44)  LDD1181  [2]
 LDCM0303  AC41 PaTu 8988t C82(1.07)  LDD1182  [2]
 LDCM0304  AC42 PaTu 8988t C82(1.02)  LDD1183  [2]
 LDCM0305  AC43 PaTu 8988t C82(1.03)  LDD1184  [2]
 LDCM0306  AC44 PaTu 8988t C82(1.02)  LDD1185  [2]
 LDCM0307  AC45 PaTu 8988t C82(1.00)  LDD1186  [2]
 LDCM0308  AC46 HEK-293T C467(1.04)  LDD1547  [3]
 LDCM0309  AC47 HEK-293T C467(1.06)  LDD1548  [3]
 LDCM0310  AC48 HEK-293T C467(1.03); C95(1.03); C335(1.05)  LDD1549  [3]
 LDCM0312  AC5 HEK-293T C467(0.99); C95(0.98)  LDD1551  [3]
 LDCM0313  AC50 HEK-293T C467(0.98)  LDD1552  [3]
 LDCM0316  AC53 HEK-293T C467(1.01); C95(1.07)  LDD1555  [3]
 LDCM0317  AC54 HEK-293T C467(1.05)  LDD1556  [3]
 LDCM0318  AC55 HEK-293T C467(1.01)  LDD1557  [3]
 LDCM0319  AC56 HEK-293T C467(1.05); C95(1.01); C335(1.00)  LDD1558  [3]
 LDCM0320  AC57 HEK-293T C82(1.03)  LDD0918  [2]
 LDCM0321  AC58 HEK-293T C82(1.25)  LDD0919  [2]
 LDCM0322  AC59 HEK-293T C82(1.17)  LDD0920  [2]
 LDCM0323  AC6 HEK-293T C467(1.15)  LDD1562  [3]
 LDCM0324  AC60 HEK-293T C82(1.36)  LDD0922  [2]
 LDCM0325  AC61 HEK-293T C82(0.59)  LDD0923  [2]
 LDCM0326  AC62 HEK-293T C82(0.92)  LDD0924  [2]
 LDCM0327  AC63 HEK-293T C82(0.62)  LDD0925  [2]
 LDCM0328  AC64 HEK-293T C82(0.88)  LDD0926  [2]
 LDCM0329  AC65 HEK-293T C82(0.56)  LDD0927  [2]
 LDCM0330  AC66 HEK-293T C82(0.98)  LDD0928  [2]
 LDCM0331  AC67 HEK-293T C82(0.81)  LDD0929  [2]
 LDCM0334  AC7 HEK-293T C467(1.00)  LDD1568  [3]
 LDCM0345  AC8 HEK-293T C467(1.05); C95(0.99); C335(0.90)  LDD1569  [3]
 LDCM0365  AC98 HEK-293T C82(0.93)  LDD0963  [2]
 LDCM0366  AC99 HEK-293T C82(3.08)  LDD0964  [2]
 LDCM0248  AKOS034007472 HEK-293T C467(0.99); C95(1.04)  LDD1511  [3]
 LDCM0275  AKOS034007705 HEK-293T C467(0.95); C95(1.08); C335(0.84)  LDD1514  [3]
 LDCM0367  CL1 HEK-293T C467(0.99)  LDD1571  [3]
 LDCM0368  CL10 HEK-293T C467(1.11)  LDD1572  [3]
 LDCM0370  CL101 HEK-293T C467(1.03)  LDD1574  [3]
 LDCM0371  CL102 HEK-293T C467(0.99)  LDD1575  [3]
 LDCM0372  CL103 HEK-293T C467(1.06); C95(1.08)  LDD1576  [3]
 LDCM0374  CL105 HEK-293T C467(1.02)  LDD1578  [3]
 LDCM0375  CL106 HEK-293T C467(0.92)  LDD1579  [3]
 LDCM0376  CL107 HEK-293T C467(1.01); C95(0.99)  LDD1580  [3]
 LDCM0378  CL109 HEK-293T C467(0.96)  LDD1582  [3]
 LDCM0379  CL11 HEK-293T C467(0.98)  LDD1583  [3]
 LDCM0380  CL110 HEK-293T C467(0.98)  LDD1584  [3]
 LDCM0381  CL111 HEK-293T C467(0.99); C95(0.95)  LDD1585  [3]
 LDCM0383  CL113 HEK-293T C467(1.06)  LDD1587  [3]
 LDCM0384  CL114 HEK-293T C467(1.12)  LDD1588  [3]
 LDCM0385  CL115 HEK-293T C467(1.03); C95(1.01)  LDD1589  [3]
 LDCM0387  CL117 PaTu 8988t C82(0.95)  LDD1266  [2]
 LDCM0388  CL118 PaTu 8988t C82(0.86)  LDD1267  [2]
 LDCM0389  CL119 PaTu 8988t C82(1.24)  LDD1268  [2]
 LDCM0390  CL12 HEK-293T C467(1.09); C95(1.09); C335(1.03)  LDD1594  [3]
 LDCM0391  CL120 PaTu 8988t C82(1.55)  LDD1270  [2]
 LDCM0392  CL121 HEK-293T C467(1.06)  LDD1596  [3]
 LDCM0393  CL122 HEK-293T C467(0.89)  LDD1597  [3]
 LDCM0394  CL123 HEK-293T C467(0.97); C95(1.11)  LDD1598  [3]
 LDCM0396  CL125 HEK-293T C82(1.01)  LDD0994  [2]
 LDCM0397  CL126 HEK-293T C82(0.91)  LDD0995  [2]
 LDCM0398  CL127 HEK-293T C82(1.22)  LDD0996  [2]
 LDCM0399  CL128 HEK-293T C82(1.22)  LDD0997  [2]
 LDCM0400  CL13 HEK-293T C467(1.08)  LDD1604  [3]
 LDCM0401  CL14 HEK-293T C467(0.91)  LDD1605  [3]
 LDCM0402  CL15 HEK-293T C467(0.98); C95(1.01)  LDD1606  [3]
 LDCM0403  CL16 HEK-293T C82(1.17)  LDD1001  [2]
 LDCM0404  CL17 HEK-293T C82(0.87)  LDD1002  [2]
 LDCM0405  CL18 HEK-293T C82(0.46)  LDD1003  [2]
 LDCM0406  CL19 HEK-293T C82(0.72)  LDD1004  [2]
 LDCM0407  CL2 HEK-293T C467(0.85)  LDD1611  [3]
 LDCM0408  CL20 HEK-293T C82(0.72)  LDD1006  [2]
 LDCM0409  CL21 HEK-293T C82(0.52)  LDD1007  [2]
 LDCM0410  CL22 HEK-293T C82(0.53)  LDD1008  [2]
 LDCM0411  CL23 HEK-293T C82(0.84)  LDD1009  [2]
 LDCM0412  CL24 HEK-293T C82(0.67)  LDD1010  [2]
 LDCM0413  CL25 HEK-293T C82(0.59)  LDD1011  [2]
 LDCM0414  CL26 HEK-293T C82(0.76)  LDD1012  [2]
 LDCM0415  CL27 HEK-293T C82(0.78)  LDD1013  [2]
 LDCM0416  CL28 HEK-293T C82(0.95)  LDD1014  [2]
 LDCM0417  CL29 HEK-293T C82(1.02)  LDD1015  [2]
 LDCM0418  CL3 HEK-293T C467(0.98); C95(1.06)  LDD1622  [3]
 LDCM0419  CL30 HEK-293T C82(0.44)  LDD1017  [2]
 LDCM0420  CL31 HEK-293T C82(0.85)  LDD1018  [2]
 LDCM0421  CL32 HEK-293T C82(0.60)  LDD1019  [2]
 LDCM0422  CL33 HEK-293T C82(0.41)  LDD1020  [2]
 LDCM0423  CL34 HEK-293T C82(1.03)  LDD1021  [2]
 LDCM0424  CL35 HEK-293T C82(0.64)  LDD1022  [2]
 LDCM0425  CL36 HEK-293T C82(0.68)  LDD1023  [2]
 LDCM0426  CL37 HEK-293T C82(0.59)  LDD1024  [2]
 LDCM0428  CL39 HEK-293T C82(0.17)  LDD1026  [2]
 LDCM0430  CL40 HEK-293T C82(0.40)  LDD1028  [2]
 LDCM0431  CL41 HEK-293T C82(0.17)  LDD1029  [2]
 LDCM0432  CL42 HEK-293T C82(0.18)  LDD1030  [2]
 LDCM0433  CL43 HEK-293T C82(0.20)  LDD1031  [2]
 LDCM0434  CL44 HEK-293T C82(0.53)  LDD1032  [2]
 LDCM0435  CL45 HEK-293T C82(0.19)  LDD1033  [2]
 LDCM0436  CL46 HEK-293T C82(0.34)  LDD1034  [2]
 LDCM0437  CL47 HEK-293T C82(0.59)  LDD1035  [2]
 LDCM0438  CL48 HEK-293T C82(0.61)  LDD1036  [2]
 LDCM0439  CL49 HEK-293T C82(0.50)  LDD1037  [2]
 LDCM0441  CL50 HEK-293T C82(0.26)  LDD1039  [2]
 LDCM0442  CL51 HEK-293T C82(0.55)  LDD1040  [2]
 LDCM0443  CL52 HEK-293T C82(1.74)  LDD1041  [2]
 LDCM0444  CL53 HEK-293T C82(1.15)  LDD1042  [2]
 LDCM0445  CL54 HEK-293T C82(0.45)  LDD1043  [2]
 LDCM0446  CL55 HEK-293T C82(0.47)  LDD1044  [2]
 LDCM0447  CL56 HEK-293T C82(0.92)  LDD1045  [2]
 LDCM0448  CL57 HEK-293T C82(0.80)  LDD1046  [2]
 LDCM0449  CL58 HEK-293T C82(0.77)  LDD1047  [2]
 LDCM0450  CL59 HEK-293T C82(0.30)  LDD1048  [2]
 LDCM0451  CL6 HEK-293T C467(0.97)  LDD1654  [3]
 LDCM0452  CL60 HEK-293T C82(0.23)  LDD1050  [2]
 LDCM0453  CL61 HEK-293T C82(0.65)  LDD1051  [2]
 LDCM0454  CL62 HEK-293T C82(0.63)  LDD1052  [2]
 LDCM0455  CL63 HEK-293T C82(0.55)  LDD1053  [2]
 LDCM0456  CL64 HEK-293T C82(0.76)  LDD1054  [2]
 LDCM0457  CL65 HEK-293T C82(0.50)  LDD1055  [2]
 LDCM0458  CL66 HEK-293T C82(0.82)  LDD1056  [2]
 LDCM0459  CL67 HEK-293T C82(0.94)  LDD1057  [2]
 LDCM0460  CL68 HEK-293T C82(0.57)  LDD1058  [2]
 LDCM0461  CL69 HEK-293T C82(0.81)  LDD1059  [2]
 LDCM0463  CL70 HEK-293T C82(0.65)  LDD1061  [2]
 LDCM0464  CL71 HEK-293T C82(0.53)  LDD1062  [2]
 LDCM0465  CL72 HEK-293T C82(0.66)  LDD1063  [2]
 LDCM0466  CL73 HEK-293T C82(0.59)  LDD1064  [2]
 LDCM0467  CL74 HEK-293T C82(0.27)  LDD1065  [2]
 LDCM0471  CL78 HEK-293T C467(0.90)  LDD1674  [3]
 LDCM0475  CL81 HEK-293T C467(1.05); C95(1.17)  LDD1678  [3]
 LDCM0476  CL82 HEK-293T C467(1.04)  LDD1679  [3]
 LDCM0477  CL83 HEK-293T C467(1.10)  LDD1680  [3]
 LDCM0478  CL84 HEK-293T C467(1.03); C95(1.24); C335(0.91)  LDD1681  [3]
 LDCM0479  CL85 HEK-293T C467(1.00)  LDD1682  [3]
 LDCM0480  CL86 HEK-293T C467(1.03)  LDD1683  [3]
 LDCM0481  CL87 HEK-293T C467(0.98); C95(1.06)  LDD1684  [3]
 LDCM0484  CL9 HEK-293T C467(1.04); C95(1.19)  LDD1687  [3]
 LDCM0485  CL90 HEK-293T C467(1.04)  LDD1688  [3]
 LDCM0488  CL93 HEK-293T C467(1.04); C95(1.19)  LDD1691  [3]
 LDCM0489  CL94 HEK-293T C467(1.13)  LDD1692  [3]
 LDCM0490  CL95 HEK-293T C467(1.05)  LDD1693  [3]
 LDCM0491  CL96 HEK-293T C467(1.04); C95(1.08); C335(0.93)  LDD1694  [3]
 LDCM0492  CL97 HEK-293T C467(0.94)  LDD1695  [3]
 LDCM0493  CL98 HEK-293T C467(1.06)  LDD1696  [3]
 LDCM0494  CL99 HEK-293T C467(1.05); C95(0.98)  LDD1697  [3]
 LDCM0495  E2913 HEK-293T C467(0.96); C95(1.00)  LDD1698  [3]
 LDCM0468  Fragment33 HEK-293T C82(0.35)  LDD1066  [2]
 LDCM0427  Fragment51 HEK-293T C82(0.78)  LDD1025  [2]
 LDCM0022  KB02 HEK-293T C95(0.89); C467(1.06)  LDD1492  [3]
 LDCM0023  KB03 HEK-293T C95(0.88); C467(1.01)  LDD1497  [3]
 LDCM0024  KB05 HEK-293T C95(0.89); C467(1.00)  LDD1502  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 7 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein-lysine N-methyltransferase EEF2KMT (EEF2KMT) EEF2KMT family Q96G04
Serine/threonine-protein kinase N1 (PKN1) AGC Ser/Thr protein kinase family Q16512
5'-AMP-activated protein kinase catalytic subunit alpha-2 (PRKAA2) CAMK Ser/Thr protein kinase family P54646
Myotubularin-related protein 9 (MTMR9) Protein-tyrosine phosphatase family Q96QG7
Tumor susceptibility gene 101 protein (TSG101) Ubiquitin-conjugating enzyme family Q99816
E3 ubiquitin-protein ligase LNX (LNX1) . Q8TBB1
Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 (TSTD2) . Q5T7W7
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Zinc finger protein 417 (ZNF417) Krueppel C2H2-type zinc-finger protein family Q8TAU3
Other
Click To Hide/Show 20 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Autophagy protein 5 (ATG5) ATG5 family Q9H1Y0
Bystin (BYSL) Bystin family Q13895
Centromere protein P (CENPP) CENP-P/CTF19 family Q6IPU0
Testis-specific gene 10 protein (TSGA10) CEP135/TSGA10 family Q9BZW7
Cilia- and flagella-associated protein 206 (CFAP206) CFAP206 family Q8IYR0
ELL-associated factor 1 (EAF1) EAF family Q96JC9
Protein FAM161A (FAM161A) FAM161 family Q3B820
Protein FAM161B (FAM161B) FAM161 family Q96MY7
Alpha-taxilin (TXLNA) Taxilin family P40222
Beta-taxilin (TXLNB) Taxilin family Q8N3L3
Centrosomal protein of 290 kDa (CEP290) . O15078
Coatomer subunit beta (COPB1) . P53618
Coiled-coil domain-containing protein 13 (CCDC13) . Q8IYE1
Cytohesin-4 (CYTH4) . Q9UIA0
Differentially expressed in FDCP 6 homolog (DEF6) . Q9H4E7
Enkurin domain-containing protein 1 (ENKD1) . Q9H0I2
Golgin subfamily A member 1 (GOLGA1) . Q92805
Mirror-image polydactyly gene 1 protein (MIPOL1) . Q8TD10
PRKCA-binding protein (PICK1) . Q9NRD5
Rhombotin-1 (LMO1) . P25800

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402