Details of the Target

General Information of Target

Target ID LDTP04950
Target Name LIM domain transcription factor LMO4 (LMO4)
Gene Name LMO4
Gene ID 8543
Synonyms
LIM domain transcription factor LMO4; Breast tumor autoantigen; LIM domain only protein 4; LMO-4
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
Target Bioclass
Other
Function
Transcription cofactor. Plays a role in establishing motor neuron identity, in concert with MNX1, acting, at least in part, to disrupt LDB1-LHX3 complexes thereby negatively modulating interneuron genes in motor neurons.
Uniprot ID
P61968
Ensemble ID
ENST00000370542.1
HGNC ID
HGNC:6644

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C115(1.57); C118(1.57)  LDD0080  [1]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [2]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [3]
AOyne
 Probe Info  		15.00  LDD0443  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C112(1.25); C50(1.15)  LDD0812  [1]
 LDCM0215  AC10 HEK-293T C64(0.79)  LDD0813  [1]
 LDCM0226  AC11 HEK-293T C64(0.82)  LDD0824  [1]
 LDCM0230  AC113 HEK-293T C64(0.99)  LDD0828  [1]
 LDCM0231  AC114 HEK-293T C64(1.21)  LDD0829  [1]
 LDCM0232  AC115 HEK-293T C64(1.56)  LDD0830  [1]
 LDCM0233  AC116 HEK-293T C64(0.84)  LDD0831  [1]
 LDCM0234  AC117 HEK-293T C64(1.19)  LDD0832  [1]
 LDCM0235  AC118 HEK-293T C64(0.96)  LDD0833  [1]
 LDCM0236  AC119 HEK-293T C64(1.28)  LDD0834  [1]
 LDCM0237  AC12 HEK-293T C64(1.01)  LDD0835  [1]
 LDCM0238  AC120 HEK-293T C64(1.32)  LDD0836  [1]
 LDCM0239  AC121 HEK-293T C64(1.36)  LDD0837  [1]
 LDCM0240  AC122 HEK-293T C64(1.25)  LDD0838  [1]
 LDCM0241  AC123 HEK-293T C64(1.44)  LDD0839  [1]
 LDCM0242  AC124 HEK-293T C64(1.72)  LDD0840  [1]
 LDCM0243  AC125 HEK-293T C64(1.69)  LDD0841  [1]
 LDCM0244  AC126 HEK-293T C64(2.02)  LDD0842  [1]
 LDCM0245  AC127 HEK-293T C64(1.67)  LDD0843  [1]
 LDCM0246  AC128 HEK-293T C64(0.66)  LDD0844  [1]
 LDCM0247  AC129 HEK-293T C64(1.20)  LDD0845  [1]
 LDCM0249  AC130 HEK-293T C64(1.08)  LDD0847  [1]
 LDCM0250  AC131 HEK-293T C64(1.00)  LDD0848  [1]
 LDCM0251  AC132 HEK-293T C64(0.83)  LDD0849  [1]
 LDCM0252  AC133 HEK-293T C64(1.02)  LDD0850  [1]
 LDCM0253  AC134 HEK-293T C64(1.13)  LDD0851  [1]
 LDCM0254  AC135 HEK-293T C64(0.78)  LDD0852  [1]
 LDCM0255  AC136 HEK-293T C64(1.15)  LDD0853  [1]
 LDCM0256  AC137 HEK-293T C64(1.20)  LDD0854  [1]
 LDCM0257  AC138 HEK-293T C64(1.07)  LDD0855  [1]
 LDCM0258  AC139 HEK-293T C64(1.41)  LDD0856  [1]
 LDCM0259  AC14 HEK-293T C64(0.78)  LDD0857  [1]
 LDCM0260  AC140 HEK-293T C64(1.13)  LDD0858  [1]
 LDCM0261  AC141 HEK-293T C64(1.24)  LDD0859  [1]
 LDCM0262  AC142 HEK-293T C64(1.48)  LDD0860  [1]
 LDCM0263  AC143 HEK-293T C112(1.40); C64(0.66)  LDD0861  [1]
 LDCM0264  AC144 HEK-293T C112(1.58); C64(0.87)  LDD0862  [1]
 LDCM0265  AC145 HEK-293T C112(1.62); C64(1.30)  LDD0863  [1]
 LDCM0266  AC146 HEK-293T C112(1.67); C64(0.93)  LDD0864  [1]
 LDCM0267  AC147 HEK-293T C112(1.86); C64(0.74)  LDD0865  [1]
 LDCM0268  AC148 HEK-293T C112(2.09); C64(0.72)  LDD0866  [1]
 LDCM0269  AC149 HEK-293T C112(1.35); C64(0.65)  LDD0867  [1]
 LDCM0270  AC15 HEK-293T C64(0.89)  LDD0868  [1]
 LDCM0271  AC150 HEK-293T C112(1.81); C64(0.71)  LDD0869  [1]
 LDCM0272  AC151 HEK-293T C112(1.66); C64(0.96)  LDD0870  [1]
 LDCM0273  AC152 HEK-293T C112(1.83); C64(0.68)  LDD0871  [1]
 LDCM0274  AC153 HEK-293T C112(1.38); C64(0.89)  LDD0872  [1]
 LDCM0621  AC154 HEK-293T C112(1.08); C64(0.71)  LDD2162  [1]
 LDCM0622  AC155 HEK-293T C112(1.57); C64(1.07)  LDD2163  [1]
 LDCM0623  AC156 HEK-293T C112(2.03); C64(1.02)  LDD2164  [1]
 LDCM0624  AC157 HEK-293T C112(2.14); C64(1.07)  LDD2165  [1]
 LDCM0276  AC17 HEK-293T C64(1.62)  LDD0874  [1]
 LDCM0277  AC18 HEK-293T C64(1.42)  LDD0875  [1]
 LDCM0278  AC19 HEK-293T C64(1.33)  LDD0876  [1]
 LDCM0279  AC2 HEK-293T C112(1.23); C50(0.92)  LDD0877  [1]
 LDCM0280  AC20 HEK-293T C64(1.71)  LDD0878  [1]
 LDCM0281  AC21 HEK-293T C64(1.46)  LDD0879  [1]
 LDCM0282  AC22 HEK-293T C64(1.26)  LDD0880  [1]
 LDCM0283  AC23 HEK-293T C64(2.28)  LDD0881  [1]
 LDCM0284  AC24 HEK-293T C64(1.33)  LDD0882  [1]
 LDCM0285  AC25 HEK-293T C112(0.91); C64(1.74)  LDD0883  [1]
 LDCM0286  AC26 HEK-293T C112(0.90); C64(1.76)  LDD0884  [1]
 LDCM0287  AC27 HEK-293T C112(1.29); C64(1.86)  LDD0885  [1]
 LDCM0288  AC28 HEK-293T C112(1.06); C64(1.79)  LDD0886  [1]
 LDCM0289  AC29 HEK-293T C112(1.30); C64(1.92)  LDD0887  [1]
 LDCM0290  AC3 HEK-293T C112(1.13); C50(0.83)  LDD0888  [1]
 LDCM0291  AC30 HEK-293T C112(1.32); C64(1.79)  LDD0889  [1]
 LDCM0292  AC31 HEK-293T C112(1.23); C64(3.26)  LDD0890  [1]
 LDCM0293  AC32 HEK-293T C112(1.14); C64(1.98)  LDD0891  [1]
 LDCM0294  AC33 HEK-293T C112(1.40); C64(1.88)  LDD0892  [1]
 LDCM0295  AC34 HEK-293T C112(1.37); C64(2.24)  LDD0893  [1]
 LDCM0296  AC35 HEK-293T C64(1.05)  LDD0894  [1]
 LDCM0297  AC36 HEK-293T C64(1.19)  LDD0895  [1]
 LDCM0298  AC37 HEK-293T C64(0.87)  LDD0896  [1]
 LDCM0299  AC38 HEK-293T C64(1.24)  LDD0897  [1]
 LDCM0300  AC39 HEK-293T C64(1.25)  LDD0898  [1]
 LDCM0301  AC4 HEK-293T C112(1.01); C50(0.82)  LDD0899  [1]
 LDCM0302  AC40 HEK-293T C64(1.12)  LDD0900  [1]
 LDCM0303  AC41 HEK-293T C64(1.26)  LDD0901  [1]
 LDCM0304  AC42 HEK-293T C64(1.02)  LDD0902  [1]
 LDCM0305  AC43 HEK-293T C64(1.22)  LDD0903  [1]
 LDCM0306  AC44 HEK-293T C64(1.09)  LDD0904  [1]
 LDCM0307  AC45 HEK-293T C64(1.17)  LDD0905  [1]
 LDCM0308  AC46 HEK-293T C64(0.99)  LDD0906  [1]
 LDCM0309  AC47 HEK-293T C64(0.78)  LDD0907  [1]
 LDCM0310  AC48 HEK-293T C64(1.07)  LDD0908  [1]
 LDCM0311  AC49 HEK-293T C64(1.13)  LDD0909  [1]
 LDCM0312  AC5 HEK-293T C112(1.30); C50(1.25)  LDD0910  [1]
 LDCM0313  AC50 HEK-293T C64(0.96)  LDD0911  [1]
 LDCM0314  AC51 HEK-293T C64(1.40)  LDD0912  [1]
 LDCM0315  AC52 HEK-293T C64(1.42)  LDD0913  [1]
 LDCM0316  AC53 HEK-293T C64(1.24)  LDD0914  [1]
 LDCM0317  AC54 HEK-293T C64(1.09)  LDD0915  [1]
 LDCM0318  AC55 HEK-293T C64(1.02)  LDD0916  [1]
 LDCM0319  AC56 HEK-293T C64(1.13)  LDD0917  [1]
 LDCM0320  AC57 HEK-293T C112(1.11); C64(1.16)  LDD0918  [1]
 LDCM0321  AC58 HEK-293T C112(0.81); C64(1.27)  LDD0919  [1]
 LDCM0322  AC59 HEK-293T C112(0.91); C64(1.54)  LDD0920  [1]
 LDCM0323  AC6 HEK-293T C64(0.90)  LDD0921  [1]
 LDCM0324  AC60 HEK-293T C112(0.78); C64(1.14)  LDD0922  [1]
 LDCM0325  AC61 HEK-293T C112(1.56); C64(1.63)  LDD0923  [1]
 LDCM0326  AC62 HEK-293T C112(1.23); C64(1.49)  LDD0924  [1]
 LDCM0327  AC63 HEK-293T C112(1.76); C64(1.88)  LDD0925  [1]
 LDCM0328  AC64 HEK-293T C112(1.38); C64(1.86)  LDD0926  [1]
 LDCM0329  AC65 HEK-293T C112(1.60); C64(1.89)  LDD0927  [1]
 LDCM0330  AC66 HEK-293T C112(1.06); C64(1.75)  LDD0928  [1]
 LDCM0331  AC67 HEK-293T C112(1.20); C64(2.16)  LDD0929  [1]
 LDCM0332  AC68 HEK-293T C112(0.96)  LDD0930  [1]
 LDCM0333  AC69 HEK-293T C112(1.40)  LDD0931  [1]
 LDCM0334  AC7 HEK-293T C64(1.00)  LDD0932  [1]
 LDCM0335  AC70 HEK-293T C112(1.27)  LDD0933  [1]
 LDCM0336  AC71 HEK-293T C112(1.44)  LDD0934  [1]
 LDCM0337  AC72 HEK-293T C112(1.27)  LDD0935  [1]
 LDCM0338  AC73 HEK-293T C112(1.29)  LDD0936  [1]
 LDCM0339  AC74 HEK-293T C112(1.24)  LDD0937  [1]
 LDCM0340  AC75 HEK-293T C112(0.91)  LDD0938  [1]
 LDCM0341  AC76 HEK-293T C112(0.95)  LDD0939  [1]
 LDCM0342  AC77 HEK-293T C112(1.06)  LDD0940  [1]
 LDCM0343  AC78 HEK-293T C112(1.37)  LDD0941  [1]
 LDCM0344  AC79 HEK-293T C112(1.17)  LDD0942  [1]
 LDCM0345  AC8 HEK-293T C64(1.23)  LDD0943  [1]
 LDCM0346  AC80 HEK-293T C112(1.38)  LDD0944  [1]
 LDCM0347  AC81 HEK-293T C112(1.07)  LDD0945  [1]
 LDCM0348  AC82 HEK-293T C112(1.55)  LDD0946  [1]
 LDCM0349  AC83 HEK-293T C50(0.78)  LDD0947  [1]
 LDCM0350  AC84 HEK-293T C50(0.97)  LDD0948  [1]
 LDCM0351  AC85 HEK-293T C50(1.03)  LDD0949  [1]
 LDCM0352  AC86 HEK-293T C50(0.93)  LDD0950  [1]
 LDCM0353  AC87 HEK-293T C50(1.39)  LDD0951  [1]
 LDCM0354  AC88 HEK-293T C50(1.08)  LDD0952  [1]
 LDCM0355  AC89 HEK-293T C50(1.33)  LDD0953  [1]
 LDCM0357  AC90 HEK-293T C50(1.32)  LDD0955  [1]
 LDCM0358  AC91 HEK-293T C50(0.82)  LDD0956  [1]
 LDCM0359  AC92 HEK-293T C50(1.06)  LDD0957  [1]
 LDCM0360  AC93 HEK-293T C50(1.11)  LDD0958  [1]
 LDCM0361  AC94 HEK-293T C50(0.93)  LDD0959  [1]
 LDCM0362  AC95 HEK-293T C50(1.04)  LDD0960  [1]
 LDCM0363  AC96 HEK-293T C50(1.68)  LDD0961  [1]
 LDCM0364  AC97 HEK-293T C50(1.57)  LDD0962  [1]
 LDCM0248  AKOS034007472 HEK-293T C64(0.93)  LDD0846  [1]
 LDCM0356  AKOS034007680 HEK-293T C64(0.87)  LDD0954  [1]
 LDCM0275  AKOS034007705 HEK-293T C64(1.05)  LDD0873  [1]
 LDCM0367  CL1 HEK-293T C50(0.97); C64(2.28)  LDD0965  [1]
 LDCM0368  CL10 HEK-293T C50(2.21); C64(1.65)  LDD0966  [1]
 LDCM0369  CL100 HEK-293T C112(1.43); C50(0.90)  LDD0967  [1]
 LDCM0370  CL101 HEK-293T C64(1.27)  LDD0968  [1]
 LDCM0371  CL102 HEK-293T C64(0.93)  LDD0969  [1]
 LDCM0372  CL103 HEK-293T C64(1.02)  LDD0970  [1]
 LDCM0373  CL104 HEK-293T C64(0.90)  LDD0971  [1]
 LDCM0374  CL105 HEK-293T C64(1.34)  LDD0972  [1]
 LDCM0375  CL106 HEK-293T C64(1.31)  LDD0973  [1]
 LDCM0376  CL107 HEK-293T C64(1.13)  LDD0974  [1]
 LDCM0377  CL108 HEK-293T C64(0.93)  LDD0975  [1]
 LDCM0378  CL109 HEK-293T C64(1.32)  LDD0976  [1]
 LDCM0379  CL11 HEK-293T C50(1.27); C64(0.73)  LDD0977  [1]
 LDCM0380  CL110 HEK-293T C64(1.40)  LDD0978  [1]
 LDCM0381  CL111 HEK-293T C64(2.03)  LDD0979  [1]
 LDCM0382  CL112 HEK-293T C112(1.36); C64(2.17)  LDD0980  [1]
 LDCM0383  CL113 HEK-293T C112(1.40); C64(1.59)  LDD0981  [1]
 LDCM0384  CL114 HEK-293T C112(1.34); C64(1.95)  LDD0982  [1]
 LDCM0385  CL115 HEK-293T C112(1.35); C64(2.68)  LDD0983  [1]
 LDCM0386  CL116 HEK-293T C112(1.66); C64(2.03)  LDD0984  [1]
 LDCM0387  CL117 HEK-293T C64(1.49)  LDD0985  [1]
 LDCM0388  CL118 HEK-293T C64(0.86)  LDD0986  [1]
 LDCM0389  CL119 HEK-293T C64(1.11)  LDD0987  [1]
 LDCM0390  CL12 HEK-293T C50(1.13); C64(1.09)  LDD0988  [1]
 LDCM0391  CL120 HEK-293T C64(1.34)  LDD0989  [1]
 LDCM0392  CL121 HEK-293T C64(1.05)  LDD0990  [1]
 LDCM0393  CL122 HEK-293T C64(0.97)  LDD0991  [1]
 LDCM0394  CL123 HEK-293T C64(0.87)  LDD0992  [1]
 LDCM0395  CL124 HEK-293T C64(0.92)  LDD0993  [1]
 LDCM0396  CL125 HEK-293T C112(0.99); C64(1.26)  LDD0994  [1]
 LDCM0397  CL126 HEK-293T C112(0.89); C64(1.16)  LDD0995  [1]
 LDCM0398  CL127 HEK-293T C112(0.93); C64(1.05)  LDD0996  [1]
 LDCM0399  CL128 HEK-293T C112(0.74); C64(1.11)  LDD0997  [1]
 LDCM0400  CL13 HEK-293T C50(1.13); C64(1.07)  LDD0998  [1]
 LDCM0401  CL14 HEK-293T C50(1.00); C64(1.33)  LDD0999  [1]
 LDCM0402  CL15 HEK-293T C50(0.62); C64(1.42)  LDD1000  [1]
 LDCM0403  CL16 HEK-293T C50(1.29)  LDD1001  [1]
 LDCM0404  CL17 HEK-293T C50(0.58)  LDD1002  [1]
 LDCM0405  CL18 HEK-293T C50(0.98)  LDD1003  [1]
 LDCM0406  CL19 HEK-293T C50(1.10)  LDD1004  [1]
 LDCM0407  CL2 HEK-293T C50(0.98); C64(1.05)  LDD1005  [1]
 LDCM0408  CL20 HEK-293T C50(1.27)  LDD1006  [1]
 LDCM0409  CL21 HEK-293T C50(0.61)  LDD1007  [1]
 LDCM0410  CL22 HEK-293T C50(1.04)  LDD1008  [1]
 LDCM0411  CL23 HEK-293T C50(0.83)  LDD1009  [1]
 LDCM0412  CL24 HEK-293T C50(1.09)  LDD1010  [1]
 LDCM0413  CL25 HEK-293T C50(0.78)  LDD1011  [1]
 LDCM0414  CL26 HEK-293T C50(0.94)  LDD1012  [1]
 LDCM0415  CL27 HEK-293T C50(0.98)  LDD1013  [1]
 LDCM0416  CL28 HEK-293T C50(0.62)  LDD1014  [1]
 LDCM0417  CL29 HEK-293T C50(0.86)  LDD1015  [1]
 LDCM0418  CL3 HEK-293T C50(1.51); C64(0.86)  LDD1016  [1]
 LDCM0419  CL30 HEK-293T C50(0.71)  LDD1017  [1]
 LDCM0420  CL31 HEK-293T C64(1.22)  LDD1018  [1]
 LDCM0421  CL32 HEK-293T C64(1.26)  LDD1019  [1]
 LDCM0422  CL33 HEK-293T C64(1.29)  LDD1020  [1]
 LDCM0423  CL34 HEK-293T C64(1.22)  LDD1021  [1]
 LDCM0424  CL35 HEK-293T C64(1.41)  LDD1022  [1]
 LDCM0425  CL36 HEK-293T C64(1.53)  LDD1023  [1]
 LDCM0426  CL37 HEK-293T C64(1.40)  LDD1024  [1]
 LDCM0428  CL39 HEK-293T C64(1.86)  LDD1026  [1]
 LDCM0429  CL4 HEK-293T C50(1.12); C64(1.13)  LDD1027  [1]
 LDCM0430  CL40 HEK-293T C64(1.19)  LDD1028  [1]
 LDCM0431  CL41 HEK-293T C64(1.16)  LDD1029  [1]
 LDCM0432  CL42 HEK-293T C64(1.20)  LDD1030  [1]
 LDCM0433  CL43 HEK-293T C64(1.47)  LDD1031  [1]
 LDCM0434  CL44 HEK-293T C64(1.57)  LDD1032  [1]
 LDCM0435  CL45 HEK-293T C64(1.13)  LDD1033  [1]
 LDCM0436  CL46 HEK-293T C112(1.03); C50(1.45); C64(1.66)  LDD1034  [1]
 LDCM0437  CL47 HEK-293T C112(1.12); C50(1.14); C64(0.98)  LDD1035  [1]
 LDCM0438  CL48 HEK-293T C112(1.08); C50(1.23); C64(1.57)  LDD1036  [1]
 LDCM0439  CL49 HEK-293T C112(1.00); C50(1.04); C64(1.02)  LDD1037  [1]
 LDCM0440  CL5 HEK-293T C50(1.44); C64(1.41)  LDD1038  [1]
 LDCM0441  CL50 HEK-293T C112(1.08); C50(0.85); C64(1.02)  LDD1039  [1]
 LDCM0442  CL51 HEK-293T C112(1.16); C50(0.79); C64(0.95)  LDD1040  [1]
 LDCM0443  CL52 HEK-293T C112(1.07); C50(0.79); C64(0.77)  LDD1041  [1]
 LDCM0444  CL53 HEK-293T C112(1.48); C50(0.70); C64(0.67)  LDD1042  [1]
 LDCM0445  CL54 HEK-293T C112(1.04); C50(0.60); C64(0.90)  LDD1043  [1]
 LDCM0446  CL55 HEK-293T C112(1.12); C50(1.44); C64(1.15)  LDD1044  [1]
 LDCM0447  CL56 HEK-293T C112(1.28); C50(0.79); C64(1.23)  LDD1045  [1]
 LDCM0448  CL57 HEK-293T C112(1.37); C50(0.79); C64(0.76)  LDD1046  [1]
 LDCM0449  CL58 HEK-293T C112(1.25); C50(0.90); C64(0.66)  LDD1047  [1]
 LDCM0450  CL59 HEK-293T C112(1.05); C50(1.07); C64(1.25)  LDD1048  [1]
 LDCM0451  CL6 HEK-293T C50(0.85); C64(0.86)  LDD1049  [1]
 LDCM0452  CL60 HEK-293T C112(1.02); C50(1.31); C64(1.50)  LDD1050  [1]
 LDCM0459  CL67 HEK-293T C73(1.05)  LDD1662  [5]
 LDCM0462  CL7 HEK-293T C50(2.13); C64(1.05)  LDD1060  [1]
 LDCM0469  CL76 HEK-293T C112(1.06); C64(1.17)  LDD1067  [1]
 LDCM0470  CL77 HEK-293T C112(0.96); C64(0.93)  LDD1068  [1]
 LDCM0471  CL78 HEK-293T C112(0.95); C64(0.92)  LDD1069  [1]
 LDCM0472  CL79 HEK-293T C112(1.10); C64(0.79)  LDD1070  [1]
 LDCM0473  CL8 HEK-293T C50(0.85)  LDD1071  [1]
 LDCM0474  CL80 HEK-293T C112(0.98); C64(1.12)  LDD1072  [1]
 LDCM0475  CL81 HEK-293T C112(0.92); C64(1.35)  LDD1073  [1]
 LDCM0476  CL82 HEK-293T C112(0.93); C64(0.88)  LDD1074  [1]
 LDCM0477  CL83 HEK-293T C112(0.89); C64(0.82)  LDD1075  [1]
 LDCM0478  CL84 HEK-293T C112(0.92); C64(1.27)  LDD1076  [1]
 LDCM0479  CL85 HEK-293T C112(0.87); C64(1.02)  LDD1077  [1]
 LDCM0480  CL86 HEK-293T C112(0.90); C64(1.07)  LDD1078  [1]
 LDCM0481  CL87 HEK-293T C112(0.76); C64(1.09)  LDD1079  [1]
 LDCM0482  CL88 HEK-293T C112(0.84); C64(1.10)  LDD1080  [1]
 LDCM0483  CL89 HEK-293T C112(0.90); C64(1.05)  LDD1081  [1]
 LDCM0484  CL9 HEK-293T C50(1.09)  LDD1082  [1]
 LDCM0485  CL90 HEK-293T C112(0.84); C64(1.01)  LDD1083  [1]
 LDCM0486  CL91 HEK-293T C112(1.04); C50(1.19)  LDD1084  [1]
 LDCM0487  CL92 HEK-293T C112(1.47); C50(0.81)  LDD1085  [1]
 LDCM0488  CL93 HEK-293T C112(1.20); C50(0.83)  LDD1086  [1]
 LDCM0489  CL94 HEK-293T C112(1.30); C50(0.93)  LDD1087  [1]
 LDCM0490  CL95 HEK-293T C112(1.48); C50(0.78)  LDD1088  [1]
 LDCM0491  CL96 HEK-293T C112(1.00); C50(1.00)  LDD1089  [1]
 LDCM0492  CL97 HEK-293T C112(0.96); C50(0.92)  LDD1090  [1]
 LDCM0493  CL98 HEK-293T C112(1.44); C50(0.86)  LDD1091  [1]
 LDCM0494  CL99 HEK-293T C112(1.54); C50(0.73)  LDD1092  [1]
 LDCM0427  Fragment51 HEK-293T C64(1.21)  LDD1025  [1]
 LDCM0022  KB02 HCT 116 C115(1.57); C118(1.57)  LDD0080  [1]
 LDCM0023  KB03 HCT 116 C115(1.87); C118(1.87)  LDD0081  [1]
 LDCM0024  KB05 HCT 116 C115(1.73); C118(1.73)  LDD0082  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 9 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Baculoviral IAP repeat-containing protein 7 (BIRC7) IAP family Q96CA5
Nucleoside diphosphate kinase, mitochondrial (NME4) NDK family O00746
Exosome complex component RRP43 (EXOSC8) RNase PH family Q96B26
E3 ubiquitin-protein ligase RNF8 (RNF8) RNF8 family O76064
DNA excision repair protein ERCC-6-like (ERCC6L) SNF2/RAD54 helicase family Q2NKX8
Zinc finger protein RFP (TRIM27) TRIM/RBCC family P14373
Methyltransferase-like protein 27 (METTL27) . Q8N6F8
Sulfite oxidase, mitochondrial (SUOX) . P51687
Tripartite motif-containing protein 54 (TRIM54) . Q9BYV2
Transporter and channel
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Leucine zipper putative tumor suppressor 1 (LZTS1) LZTS family Q9Y250
Solute carrier family 15 member 2 (SLC15A2) Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family Q16348
Inactive serine/threonine-protein kinase TEX14 (TEX14) Protein kinase superfamily Q8IWB6
Bardet-Biedl syndrome 2 protein (BBS2) . Q9BXC9
Transcription factor
Click To Hide/Show 17 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Mothers against decapentaplegic homolog 4 (SMAD4) Dwarfin/SMAD family Q13485
Grainyhead-like protein 2 homolog (GRHL2) Grh/CP2 family Q6ISB3
Zinc finger protein Aiolos (IKZF3) Ikaros C2H2-type zinc-finger protein family Q9UKT9
RB-associated KRAB zinc finger protein (RBAK) Krueppel C2H2-type zinc-finger protein family Q9NYW8
Zinc finger and BTB domain-containing protein 43 (ZBTB43) Krueppel C2H2-type zinc-finger protein family O43298
Zinc finger protein 135 (ZNF135) Krueppel C2H2-type zinc-finger protein family P52742
Zinc finger protein 213 (ZNF213) Krueppel C2H2-type zinc-finger protein family O14771
Zinc finger protein 397 (ZNF397) Krueppel C2H2-type zinc-finger protein family Q8NF99
Zinc finger protein 467 (ZNF467) Krueppel C2H2-type zinc-finger protein family Q7Z7K2
NF-kappa-B inhibitor delta (NFKBID) NF-kappa-B inhibitor family Q8NI38
Signal transducer and activator of transcription 5B (STAT5B) Transcription factor STAT family P51692
Aryl hydrocarbon receptor nuclear translocator 2 (ARNT2) . Q9HBZ2
DNA-binding protein inhibitor ID-3 (ID3) . Q02535
Myoblast determination protein 1 (MYOD1) . P15172
Transcription factor 4 (TCF4) . P15884
Transcriptional regulator QRICH1 (QRICH1) . Q2TAL8
Zinc finger protein 202 (ZNF202) . O95125
Other
Click To Hide/Show 55 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein BANP (BANP) BANP/SMAR1 family Q8N9N5
Beta-crystallin B2 (CRYBB2) Beta/gamma-crystallin family P43320
Calcium-binding and coiled-coil domain-containing protein 2 (CALCOCO2) CALCOCO family Q13137
Cep170-like protein (CEP170P1) CEP170 family Q96L14
Conserved oligomeric Golgi complex subunit 6 (COG6) COG6 family Q9Y2V7
Reticulocalbin-1 (RCN1) CREC family Q15293
Cysteine-rich tail protein 1 (CYSRT1) CYSRT1 family A8MQ03
Protein pelota homolog (PELO) Eukaryotic release factor 1 family Q9BRX2
Protein FAM228A (FAM228A) FAM228 family Q86W67
Radial spoke head protein 6 homolog A (RSPH6A) Flagellar radial spoke RSP4/6 family Q9H0K4
Golgin subfamily A member 2 (GOLGA2) GOLGA2 family Q08379
Golgin subfamily A member 6-like protein 9 (GOLGA6L9) GOLGA6 family A6NEM1
Desmin (DES) Intermediate filament family P17661
Keratin, type I cuticular Ha1 (KRT31) Intermediate filament family Q15323
Keratin, type I cuticular Ha3-II (KRT33B) Intermediate filament family Q14525
Keratin, type I cuticular Ha4 (KRT34) Intermediate filament family O76011
Keratin, type I cuticular Ha8 (KRT38) Intermediate filament family O76015
Keratin, type I cytoskeletal 15 (KRT15) Intermediate filament family P19012
Keratin, type I cytoskeletal 39 (KRT39) Intermediate filament family Q6A163
Keratin, type I cytoskeletal 40 (KRT40) Intermediate filament family Q6A162
Keratin, type II cytoskeletal 2 oral (KRT76) Intermediate filament family Q01546
Keratin, type II cytoskeletal 74 (KRT74) Intermediate filament family Q7RTS7
Keratin, type II cytoskeletal 75 (KRT75) Intermediate filament family O95678
Keratin-associated protein 3-1 (KRTAP3-1) KRTAP type 3 family Q9BYR8
LIM domain-binding protein 1 (LDB1) LDB family Q86U70
LIM domain-binding protein 2 (LDB2) LDB family O43679
Myozenin-3 (MYOZ3) Myozenin family Q8TDC0
NEDD4-binding protein 3 (N4BP3) N4BP3 family O15049
Keratin-associated protein 11-1 (KRTAP11-1) PMG family Q8IUC1
Ropporin-1A (ROPN1) Ropporin family Q9HAT0
Cornulin (CRNN) S100-fused protein family Q9UBG3
Pre-mRNA-splicing factor SPF27 (BCAS2) SPF27 family O75934
Tuftelin-interacting protein 11 (TFIP11) TFP11/STIP family Q9UBB9
TNF receptor-associated factor 5 (TRAF5) TNF receptor-associated factor family O00463
Vacuolar protein sorting-associated protein 52 homolog (VPS52) VPS52 family Q8N1B4
TLE family member 5 (TLE5) WD repeat Groucho/TLE family Q08117
Alanine and arginine-rich domain-containing protein (AARD) . Q4LEZ3
Coiled-coil domain-containing protein 102B (CCDC102B) . Q68D86
Coiled-coil domain-containing protein 120 (CCDC120) . Q96HB5
Extracellular matrix protein 1 (ECM1) . Q16610
Four and a half LIM domains protein 3 (FHL3) . Q13643
GA-binding protein subunit beta-1 (GABPB1) . Q06547
Heat shock factor 2-binding protein (HSF2BP) . O75031
Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) . O14964
KATNB1-like protein 1 (KATNBL1) . Q9H079
KN motif and ankyrin repeat domain-containing protein 2 (KANK2) . Q63ZY3
Mitochondrial coiled-coil domain protein 1 (MCCD1) . P59942
Myomegalin (PDE4DIP) . Q5VU43
Period circadian protein homolog 2 (PER2) . O15055
Regulator of DNA class I crossover intermediates 1 (REDIC1) . Q86WS4
RNA-binding protein with multiple splicing (RBPMS) . Q93062
Ubiquilin-2 (UBQLN2) . Q9UHD9
Uncharacterized protein KIAA1958 (KIAA1958) . Q8N8K9
Vimentin-type intermediate filament-associated coiled-coil protein (VMAC) . Q2NL98
Zinc finger MYND domain-containing protein 12 (ZMYND12) . Q9H0C1

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
3 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
4 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
5 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402