Details of the Target

General Information of Target

Target ID LDTP00460
Target Name Probable proton-coupled zinc antiporter SLC30A4 (SLC30A4)
Gene Name SLC30A4
Gene ID 7782
Synonyms
ZNT4; Probable proton-coupled zinc antiporter SLC30A4; Solute carrier family 30 member 4; Zinc transporter 4; ZnT-4
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAGSGAWKRLKSMLRKDDAPLFLNDTSAFDFSDEAGDEGLSRFNKLRVVVADDGSEAPER
PVNGAHPTLQADDDSLLDQDLPLTNSQLSLKVDSCDNCSKQREILKQRKVKARLTIAAVL
YLLFMIGELVGGYIANSLAIMTDALHMLTDLSAIILTLLALWLSSKSPTKRFTFGFHRLE
VLSAMISVLLVYILMGFLLYEAVQRTIHMNYEINGDIMLITAAVGVAVNVIMGFLLNQSG
HRHSHSHSLPSNSPTRGSGCERNHGQDSLAVRAAFVHALGDLVQSVGVLIAAYIIRFKPE
YKIADPICTYVFSLLVAFTTFRIIWDTVVIILEGVPSHLNVDYIKEALMKIEDVYSVEDL
NIWSLTSGKSTAIVHIQLIPGSSSKWEEVQSKANHLLLNTFGMYRCTIQLQSYRQEVDRT
CANCQSSSP
Target Bioclass
Transporter and channel
Family
Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family, SLC30A subfamily
Subcellular location
Endosome membrane
Function Probable proton-coupled zinc ion antiporter mediating zinc import from cytoplasm potentially into the endocytic compartment. Controls zinc deposition in milk.
Uniprot ID
O14863
Ensemble ID
ENST00000261867.5
HGNC ID
HGNC:11015

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C95(0.94); C98(0.83)  LDD0812  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C95(0.94); C98(0.83)  LDD0812  [1]
 LDCM0215  AC10 HEK-293T C98(0.50)  LDD0813  [1]
 LDCM0216  AC100 HEK-293T C98(0.68)  LDD0814  [1]
 LDCM0217  AC101 HEK-293T C98(1.16)  LDD0815  [1]
 LDCM0218  AC102 HEK-293T C98(0.55)  LDD0816  [1]
 LDCM0219  AC103 HEK-293T C98(1.06)  LDD0817  [1]
 LDCM0220  AC104 HEK-293T C98(1.97)  LDD0818  [1]
 LDCM0221  AC105 HEK-293T C98(0.97)  LDD0819  [1]
 LDCM0222  AC106 HEK-293T C98(0.57)  LDD0820  [1]
 LDCM0223  AC107 HEK-293T C98(0.81)  LDD0821  [1]
 LDCM0224  AC108 HEK-293T C98(1.25)  LDD0822  [1]
 LDCM0225  AC109 HEK-293T C98(0.84)  LDD0823  [1]
 LDCM0226  AC11 HEK-293T C98(0.64)  LDD0824  [1]
 LDCM0227  AC110 HEK-293T C98(0.55)  LDD0825  [1]
 LDCM0228  AC111 HEK-293T C98(0.60)  LDD0826  [1]
 LDCM0229  AC112 HEK-293T C98(0.77)  LDD0827  [1]
 LDCM0230  AC113 HEK-293T C98(0.92)  LDD0828  [1]
 LDCM0231  AC114 HEK-293T C98(0.83)  LDD0829  [1]
 LDCM0232  AC115 HEK-293T C98(0.64)  LDD0830  [1]
 LDCM0233  AC116 HEK-293T C98(0.66)  LDD0831  [1]
 LDCM0234  AC117 HEK-293T C98(0.65)  LDD0832  [1]
 LDCM0235  AC118 HEK-293T C98(0.72)  LDD0833  [1]
 LDCM0236  AC119 HEK-293T C98(0.68)  LDD0834  [1]
 LDCM0237  AC12 HEK-293T C98(0.76)  LDD0835  [1]
 LDCM0238  AC120 HEK-293T C98(1.22)  LDD0836  [1]
 LDCM0239  AC121 HEK-293T C98(1.03)  LDD0837  [1]
 LDCM0240  AC122 HEK-293T C98(1.04)  LDD0838  [1]
 LDCM0241  AC123 HEK-293T C98(0.88)  LDD0839  [1]
 LDCM0242  AC124 HEK-293T C98(0.70)  LDD0840  [1]
 LDCM0243  AC125 HEK-293T C98(0.87)  LDD0841  [1]
 LDCM0244  AC126 HEK-293T C98(1.60)  LDD0842  [1]
 LDCM0245  AC127 HEK-293T C98(0.80)  LDD0843  [1]
 LDCM0246  AC128 HEK-293T C95(1.06); C98(1.09)  LDD0844  [1]
 LDCM0247  AC129 HEK-293T C95(1.14); C98(0.89)  LDD0845  [1]
 LDCM0249  AC130 HEK-293T C95(0.98); C98(0.91)  LDD0847  [1]
 LDCM0250  AC131 HEK-293T C95(1.02); C98(0.85)  LDD0848  [1]
 LDCM0251  AC132 HEK-293T C95(1.34); C98(1.00)  LDD0849  [1]
 LDCM0252  AC133 HEK-293T C95(1.10); C98(0.88)  LDD0850  [1]
 LDCM0253  AC134 HEK-293T C95(1.05); C98(0.86)  LDD0851  [1]
 LDCM0254  AC135 HEK-293T C95(1.01); C98(0.83)  LDD0852  [1]
 LDCM0255  AC136 HEK-293T C95(1.01); C98(0.84)  LDD0853  [1]
 LDCM0256  AC137 HEK-293T C95(1.32); C98(1.13)  LDD0854  [1]
 LDCM0257  AC138 HEK-293T C95(1.15); C98(0.99)  LDD0855  [1]
 LDCM0258  AC139 HEK-293T C95(1.09); C98(0.91)  LDD0856  [1]
 LDCM0259  AC14 HEK-293T C98(0.49)  LDD0857  [1]
 LDCM0260  AC140 HEK-293T C95(1.03); C98(0.82)  LDD0858  [1]
 LDCM0261  AC141 HEK-293T C95(1.06); C98(0.87)  LDD0859  [1]
 LDCM0262  AC142 HEK-293T C95(1.14); C98(1.00)  LDD0860  [1]
 LDCM0263  AC143 PaTu 8988t C95(1.22); C98(1.22)  LDD1142  [1]
 LDCM0264  AC144 PaTu 8988t C95(1.08); C98(1.08)  LDD1143  [1]
 LDCM0265  AC145 PaTu 8988t C95(1.16); C98(1.16)  LDD1144  [1]
 LDCM0266  AC146 PaTu 8988t C95(1.09); C98(1.09)  LDD1145  [1]
 LDCM0267  AC147 PaTu 8988t C95(1.18); C98(1.18)  LDD1146  [1]
 LDCM0268  AC148 PaTu 8988t C95(1.16); C98(1.16)  LDD1147  [1]
 LDCM0269  AC149 PaTu 8988t C95(1.37); C98(1.37)  LDD1148  [1]
 LDCM0270  AC15 HEK-293T C98(0.44)  LDD0868  [1]
 LDCM0271  AC150 PaTu 8988t C95(1.31); C98(1.31)  LDD1150  [1]
 LDCM0272  AC151 PaTu 8988t C95(1.34); C98(1.34)  LDD1151  [1]
 LDCM0273  AC152 PaTu 8988t C95(1.51); C98(1.51)  LDD1152  [1]
 LDCM0274  AC153 PaTu 8988t C95(1.27); C98(1.27)  LDD1153  [1]
 LDCM0621  AC154 PaTu 8988t C95(1.28); C98(1.28)  LDD2166  [1]
 LDCM0622  AC155 PaTu 8988t C95(1.25); C98(1.25)  LDD2167  [1]
 LDCM0623  AC156 PaTu 8988t C95(1.34); C98(1.34)  LDD2168  [1]
 LDCM0624  AC157 PaTu 8988t C95(1.29); C98(1.29)  LDD2169  [1]
 LDCM0276  AC17 HEK-293T C95(1.49); C98(1.10)  LDD0874  [1]
 LDCM0277  AC18 HEK-293T C95(1.41); C98(1.12)  LDD0875  [1]
 LDCM0278  AC19 HEK-293T C95(1.38); C98(1.22)  LDD0876  [1]
 LDCM0279  AC2 HEK-293T C95(1.12); C98(1.03)  LDD0877  [1]
 LDCM0280  AC20 HEK-293T C95(1.20); C98(1.13)  LDD0878  [1]
 LDCM0281  AC21 HEK-293T C95(1.66); C98(1.28)  LDD0879  [1]
 LDCM0282  AC22 HEK-293T C95(1.29); C98(1.19)  LDD0880  [1]
 LDCM0283  AC23 HEK-293T C95(1.43); C98(1.16)  LDD0881  [1]
 LDCM0284  AC24 HEK-293T C95(1.63); C98(1.09)  LDD0882  [1]
 LDCM0290  AC3 HEK-293T C95(1.01); C98(1.00)  LDD0888  [1]
 LDCM0301  AC4 HEK-293T C95(0.97); C98(0.89)  LDD0899  [1]
 LDCM0308  AC46 HEK-293T C98(0.72)  LDD0906  [1]
 LDCM0309  AC47 HEK-293T C98(0.74)  LDD0907  [1]
 LDCM0310  AC48 HEK-293T C98(0.52)  LDD0908  [1]
 LDCM0311  AC49 HEK-293T C98(0.73)  LDD0909  [1]
 LDCM0312  AC5 HEK-293T C95(0.96); C98(0.88)  LDD0910  [1]
 LDCM0313  AC50 HEK-293T C98(0.74)  LDD0911  [1]
 LDCM0314  AC51 HEK-293T C98(0.98)  LDD0912  [1]
 LDCM0315  AC52 HEK-293T C98(0.83)  LDD0913  [1]
 LDCM0316  AC53 HEK-293T C98(0.83)  LDD0914  [1]
 LDCM0317  AC54 HEK-293T C98(0.64)  LDD0915  [1]
 LDCM0318  AC55 HEK-293T C98(0.64)  LDD0916  [1]
 LDCM0319  AC56 HEK-293T C98(0.76)  LDD0917  [1]
 LDCM0320  AC57 HEK-293T C95(0.84); C98(0.84)  LDD0918  [1]
 LDCM0321  AC58 HEK-293T C95(0.74); C98(0.74)  LDD0919  [1]
 LDCM0322  AC59 HEK-293T C95(0.98); C98(0.98)  LDD0920  [1]
 LDCM0323  AC6 HEK-293T C98(0.65)  LDD0921  [1]
 LDCM0324  AC60 HEK-293T C95(0.89); C98(0.89)  LDD0922  [1]
 LDCM0325  AC61 HEK-293T C95(0.86); C98(0.86)  LDD0923  [1]
 LDCM0326  AC62 HEK-293T C95(1.00); C98(1.00)  LDD0924  [1]
 LDCM0327  AC63 HEK-293T C95(0.99); C98(0.99)  LDD0925  [1]
 LDCM0328  AC64 HEK-293T C95(0.94); C98(0.94)  LDD0926  [1]
 LDCM0329  AC65 HEK-293T C95(0.97); C98(0.97)  LDD0927  [1]
 LDCM0330  AC66 HEK-293T C95(0.95); C98(0.95)  LDD0928  [1]
 LDCM0331  AC67 HEK-293T C95(0.92); C98(0.92)  LDD0929  [1]
 LDCM0332  AC68 HEK-293T C98(0.70)  LDD0930  [1]
 LDCM0333  AC69 HEK-293T C98(0.67)  LDD0931  [1]
 LDCM0334  AC7 HEK-293T C98(0.68)  LDD0932  [1]
 LDCM0335  AC70 HEK-293T C98(0.49)  LDD0933  [1]
 LDCM0336  AC71 HEK-293T C98(0.63)  LDD0934  [1]
 LDCM0337  AC72 HEK-293T C98(0.53)  LDD0935  [1]
 LDCM0338  AC73 HEK-293T C98(0.47)  LDD0936  [1]
 LDCM0339  AC74 HEK-293T C98(0.40)  LDD0937  [1]
 LDCM0340  AC75 HEK-293T C98(0.46)  LDD0938  [1]
 LDCM0341  AC76 HEK-293T C98(0.56)  LDD0939  [1]
 LDCM0342  AC77 HEK-293T C98(0.54)  LDD0940  [1]
 LDCM0343  AC78 HEK-293T C98(0.63)  LDD0941  [1]
 LDCM0344  AC79 HEK-293T C98(0.66)  LDD0942  [1]
 LDCM0345  AC8 HEK-293T C98(0.47)  LDD0943  [1]
 LDCM0346  AC80 HEK-293T C98(0.35)  LDD0944  [1]
 LDCM0347  AC81 HEK-293T C98(0.40)  LDD0945  [1]
 LDCM0348  AC82 HEK-293T C98(0.35)  LDD0946  [1]
 LDCM0365  AC98 HEK-293T C98(1.23)  LDD0963  [1]
 LDCM0366  AC99 HEK-293T C98(0.99)  LDD0964  [1]
 LDCM0248  AKOS034007472 HEK-293T C98(0.73)  LDD0846  [1]
 LDCM0356  AKOS034007680 HEK-293T C98(0.49)  LDD0954  [1]
 LDCM0275  AKOS034007705 HEK-293T C98(0.56)  LDD0873  [1]
 LDCM0367  CL1 HEK-293T C95(1.25); C98(1.25)  LDD0965  [1]
 LDCM0368  CL10 HEK-293T C95(1.47); C98(1.47)  LDD0966  [1]
 LDCM0369  CL100 HEK-293T C95(0.79); C98(0.77)  LDD0967  [1]
 LDCM0370  CL101 HEK-293T C98(0.66)  LDD0968  [1]
 LDCM0371  CL102 HEK-293T C98(0.53)  LDD0969  [1]
 LDCM0372  CL103 HEK-293T C98(0.58)  LDD0970  [1]
 LDCM0373  CL104 HEK-293T C98(0.50)  LDD0971  [1]
 LDCM0374  CL105 HEK-293T C95(1.06); C98(0.97)  LDD0972  [1]
 LDCM0375  CL106 HEK-293T C95(1.27); C98(1.29)  LDD0973  [1]
 LDCM0376  CL107 HEK-293T C95(1.37); C98(1.30)  LDD0974  [1]
 LDCM0377  CL108 HEK-293T C95(1.24); C98(1.15)  LDD0975  [1]
 LDCM0378  CL109 HEK-293T C95(1.41); C98(1.34)  LDD0976  [1]
 LDCM0379  CL11 HEK-293T C95(0.84); C98(0.84)  LDD0977  [1]
 LDCM0380  CL110 HEK-293T C95(1.48); C98(1.22)  LDD0978  [1]
 LDCM0381  CL111 HEK-293T C95(1.28); C98(1.08)  LDD0979  [1]
 LDCM0390  CL12 HEK-293T C95(1.00); C98(1.00)  LDD0988  [1]
 LDCM0392  CL121 HEK-293T C98(0.74)  LDD0990  [1]
 LDCM0393  CL122 HEK-293T C98(0.63)  LDD0991  [1]
 LDCM0394  CL123 HEK-293T C98(0.85)  LDD0992  [1]
 LDCM0395  CL124 HEK-293T C98(0.68)  LDD0993  [1]
 LDCM0396  CL125 HEK-293T C95(0.82); C98(0.82)  LDD0994  [1]
 LDCM0397  CL126 HEK-293T C95(0.98); C98(0.98)  LDD0995  [1]
 LDCM0398  CL127 HEK-293T C95(0.74); C98(0.74)  LDD0996  [1]
 LDCM0399  CL128 HEK-293T C95(1.19); C98(1.19)  LDD0997  [1]
 LDCM0400  CL13 HEK-293T C95(0.95); C98(0.95)  LDD0998  [1]
 LDCM0401  CL14 HEK-293T C95(1.07); C98(1.07)  LDD0999  [1]
 LDCM0402  CL15 HEK-293T C95(1.03); C98(1.03)  LDD1000  [1]
 LDCM0403  CL16 HEK-293T C98(1.19)  LDD1001  [1]
 LDCM0404  CL17 HEK-293T C98(1.44)  LDD1002  [1]
 LDCM0405  CL18 HEK-293T C98(1.28)  LDD1003  [1]
 LDCM0406  CL19 HEK-293T C98(0.89)  LDD1004  [1]
 LDCM0407  CL2 HEK-293T C95(0.82); C98(0.82)  LDD1005  [1]
 LDCM0408  CL20 HEK-293T C98(1.47)  LDD1006  [1]
 LDCM0409  CL21 HEK-293T C98(1.26)  LDD1007  [1]
 LDCM0410  CL22 HEK-293T C98(2.23)  LDD1008  [1]
 LDCM0411  CL23 HEK-293T C98(2.76)  LDD1009  [1]
 LDCM0412  CL24 HEK-293T C98(1.89)  LDD1010  [1]
 LDCM0413  CL25 HEK-293T C98(1.71)  LDD1011  [1]
 LDCM0414  CL26 HEK-293T C98(1.69)  LDD1012  [1]
 LDCM0415  CL27 HEK-293T C98(1.61)  LDD1013  [1]
 LDCM0416  CL28 HEK-293T C98(1.46)  LDD1014  [1]
 LDCM0417  CL29 HEK-293T C98(1.56)  LDD1015  [1]
 LDCM0418  CL3 HEK-293T C95(1.00); C98(1.00)  LDD1016  [1]
 LDCM0419  CL30 HEK-293T C98(2.41)  LDD1017  [1]
 LDCM0420  CL31 HEK-293T C95(1.00); C98(1.00)  LDD1018  [1]
 LDCM0421  CL32 HEK-293T C95(0.92); C98(0.92)  LDD1019  [1]
 LDCM0422  CL33 HEK-293T C95(1.23); C98(1.23)  LDD1020  [1]
 LDCM0423  CL34 HEK-293T C95(0.96); C98(0.96)  LDD1021  [1]
 LDCM0424  CL35 HEK-293T C95(0.91); C98(0.91)  LDD1022  [1]
 LDCM0425  CL36 HEK-293T C95(0.98); C98(0.98)  LDD1023  [1]
 LDCM0426  CL37 HEK-293T C95(0.96); C98(0.96)  LDD1024  [1]
 LDCM0428  CL39 HEK-293T C95(1.04); C98(1.04)  LDD1026  [1]
 LDCM0429  CL4 HEK-293T C95(1.07); C98(1.07)  LDD1027  [1]
 LDCM0430  CL40 HEK-293T C95(0.96); C98(0.96)  LDD1028  [1]
 LDCM0431  CL41 HEK-293T C95(1.02); C98(1.02)  LDD1029  [1]
 LDCM0432  CL42 HEK-293T C95(0.87); C98(0.87)  LDD1030  [1]
 LDCM0433  CL43 HEK-293T C95(0.81); C98(0.81)  LDD1031  [1]
 LDCM0434  CL44 HEK-293T C95(0.90); C98(0.90)  LDD1032  [1]
 LDCM0435  CL45 HEK-293T C95(0.92); C98(0.92)  LDD1033  [1]
 LDCM0436  CL46 HEK-293T C95(1.04); C98(0.89)  LDD1034  [1]
 LDCM0437  CL47 HEK-293T C95(1.05); C98(0.87)  LDD1035  [1]
 LDCM0438  CL48 HEK-293T C95(1.09); C98(0.98)  LDD1036  [1]
 LDCM0439  CL49 HEK-293T C95(1.04); C98(0.99)  LDD1037  [1]
 LDCM0440  CL5 HEK-293T C95(0.99); C98(0.99)  LDD1038  [1]
 LDCM0441  CL50 HEK-293T C95(0.97); C98(0.90)  LDD1039  [1]
 LDCM0442  CL51 HEK-293T C95(1.22); C98(1.04)  LDD1040  [1]
 LDCM0443  CL52 HEK-293T C95(1.10); C98(1.07)  LDD1041  [1]
 LDCM0444  CL53 HEK-293T C95(1.45); C98(1.13)  LDD1042  [1]
 LDCM0445  CL54 HEK-293T C95(1.03); C98(0.90)  LDD1043  [1]
 LDCM0446  CL55 HEK-293T C95(0.92); C98(0.74)  LDD1044  [1]
 LDCM0447  CL56 HEK-293T C95(1.21); C98(1.01)  LDD1045  [1]
 LDCM0448  CL57 HEK-293T C95(1.14); C98(1.06)  LDD1046  [1]
 LDCM0449  CL58 HEK-293T C95(1.10); C98(0.86)  LDD1047  [1]
 LDCM0450  CL59 HEK-293T C95(1.29); C98(1.17)  LDD1048  [1]
 LDCM0451  CL6 HEK-293T C95(1.18); C98(1.18)  LDD1049  [1]
 LDCM0452  CL60 HEK-293T C95(1.11); C98(0.97)  LDD1050  [1]
 LDCM0453  CL61 HEK-293T C95(1.04); C98(1.04)  LDD1051  [1]
 LDCM0454  CL62 HEK-293T C95(1.09); C98(1.09)  LDD1052  [1]
 LDCM0455  CL63 HEK-293T C95(1.08); C98(1.08)  LDD1053  [1]
 LDCM0456  CL64 HEK-293T C95(1.72); C98(1.72)  LDD1054  [1]
 LDCM0457  CL65 HEK-293T C95(1.05); C98(1.05)  LDD1055  [1]
 LDCM0458  CL66 HEK-293T C95(0.96); C98(0.96)  LDD1056  [1]
 LDCM0459  CL67 HEK-293T C95(1.02); C98(1.02)  LDD1057  [1]
 LDCM0460  CL68 HEK-293T C95(1.14); C98(1.14)  LDD1058  [1]
 LDCM0461  CL69 HEK-293T C95(1.23); C98(1.23)  LDD1059  [1]
 LDCM0462  CL7 HEK-293T C95(1.07); C98(1.07)  LDD1060  [1]
 LDCM0463  CL70 HEK-293T C95(1.06); C98(1.06)  LDD1061  [1]
 LDCM0464  CL71 HEK-293T C95(1.05); C98(1.05)  LDD1062  [1]
 LDCM0465  CL72 HEK-293T C95(1.07); C98(1.07)  LDD1063  [1]
 LDCM0466  CL73 HEK-293T C95(1.19); C98(1.19)  LDD1064  [1]
 LDCM0467  CL74 HEK-293T C95(1.01); C98(1.01)  LDD1065  [1]
 LDCM0469  CL76 HEK-293T C95(0.93); C98(0.93)  LDD1067  [1]
 LDCM0470  CL77 HEK-293T C95(1.20); C98(1.20)  LDD1068  [1]
 LDCM0471  CL78 HEK-293T C95(1.04); C98(1.04)  LDD1069  [1]
 LDCM0472  CL79 HEK-293T C95(0.98); C98(0.98)  LDD1070  [1]
 LDCM0473  CL8 HEK-293T C95(1.21); C98(1.74)  LDD1071  [1]
 LDCM0474  CL80 HEK-293T C95(0.92); C98(0.92)  LDD1072  [1]
 LDCM0475  CL81 HEK-293T C95(1.05); C98(1.05)  LDD1073  [1]
 LDCM0476  CL82 HEK-293T C95(0.95); C98(0.95)  LDD1074  [1]
 LDCM0477  CL83 HEK-293T C95(0.93); C98(0.93)  LDD1075  [1]
 LDCM0478  CL84 HEK-293T C95(0.96); C98(0.96)  LDD1076  [1]
 LDCM0479  CL85 HEK-293T C95(1.10); C98(1.10)  LDD1077  [1]
 LDCM0480  CL86 HEK-293T C95(1.12); C98(1.12)  LDD1078  [1]
 LDCM0481  CL87 HEK-293T C95(0.91); C98(0.91)  LDD1079  [1]
 LDCM0482  CL88 HEK-293T C95(1.12); C98(1.12)  LDD1080  [1]
 LDCM0483  CL89 HEK-293T C95(0.98); C98(0.98)  LDD1081  [1]
 LDCM0484  CL9 HEK-293T C95(1.17); C98(1.10)  LDD1082  [1]
 LDCM0485  CL90 HEK-293T C95(1.48); C98(1.48)  LDD1083  [1]
 LDCM0486  CL91 HEK-293T C95(1.00); C98(1.02)  LDD1084  [1]
 LDCM0487  CL92 HEK-293T C95(1.04); C98(0.93)  LDD1085  [1]
 LDCM0488  CL93 HEK-293T C95(0.91); C98(0.98)  LDD1086  [1]
 LDCM0489  CL94 HEK-293T C95(0.96); C98(0.83)  LDD1087  [1]
 LDCM0490  CL95 HEK-293T C95(1.12); C98(0.90)  LDD1088  [1]
 LDCM0491  CL96 HEK-293T C95(0.93); C98(0.86)  LDD1089  [1]
 LDCM0492  CL97 HEK-293T C95(1.22); C98(1.01)  LDD1090  [1]
 LDCM0493  CL98 HEK-293T C95(1.06); C98(0.92)  LDD1091  [1]
 LDCM0494  CL99 HEK-293T C95(1.11); C98(0.92)  LDD1092  [1]
 LDCM0468  Fragment33 HEK-293T C95(1.64); C98(1.64)  LDD1066  [1]
 LDCM0427  Fragment51 HEK-293T C95(1.01); C98(1.01)  LDD1025  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transporter and channel
Click To Hide/Show 6 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Calcium/manganese antiporter SLC30A10 (SLC30A10) Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family Q6XR72
Probable proton-coupled zinc antiporter SLC30A3 (SLC30A3) Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family Q99726
Proton-coupled zinc antiporter SLC30A2 (SLC30A2) Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family Q9BRI3
Ceroid-lipofuscinosis neuronal protein 6 (CLN6) . Q9NWW5
Transmembrane protein 100 (TMEM100) . Q9NV29
Transmembrane protein 60 (TMEM60) . Q9H2L4
GPCR
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Frizzled-7 (FZD7) G-protein coupled receptor Fz/Smo family O75084
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Butyrophilin subfamily 2 member A2 (BTN2A2) BTN/MOG family Q8WVV5
Cytokine and receptor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Tumor necrosis factor (TNF) Tumor necrosis factor family P01375
Tumor necrosis factor receptor superfamily member 10C (TNFRSF10C) . O14798
Other
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Neuronal vesicle trafficking-associated protein 1 (NSG1) NSG family P42857
Leptin receptor overlapping transcript-like 1 (LEPROTL1) OB-RGRP/VPS55 family O95214
Stress-associated endoplasmic reticulum protein 2 (SERP2) RAMP4 family Q8N6R1
Protein YIPF6 (YIPF6) YIP1 family Q96EC8
Immediate early response 3-interacting protein 1 (IER3IP1) YOS1 family Q9Y5U9

The Drug(s) Related To This Target

Approved
Click To Hide/Show 2 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Zinc Chloride . DB14533
Zinc Sulfate Unspecified Form . DB14548

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.