General Information of Experiment

Probe Name C261  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 11.9
 LDTP10887  Synaptic vesicle membrane protein VAT-1 homolog (VAT1) 8.4
 LDTP09256  Putative phospholipase B-like 2 (PLBD2) 8.1
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 7.8
 LDTP15988  Probable serine carboxypeptidase CPVL (CPVL) 7.5
Transporter and channel
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 11.4
 LDTP02071  Amyloid-beta precursor protein (APP) 6.8
 LDTP17641  Solute carrier family 35 member F2 (SLC35F2) 5.6
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 5.0
Other
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00105  Protein unc-119 homolog B (UNC119B) 9.3
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 7.4
 LDTP00779  Trans-Golgi network integral membrane protein 2 (TGOLN2) 7.2

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587