General Information of Experiment

Probe Name C111  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 7 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP05029  Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) 10.4
 LDTP06618  ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) 6.6
 LDTP03374  Peptidyl-prolyl cis-trans isomerase FKBP2 (FKBP2) 6.4
 LDTP03417  Proteasome subunit beta type-4 (PSMB4) 6.2
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 5.9
 LDTP04185  Glutamate--cysteine ligase catalytic subunit (GCLC) 5.7
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 5.2
Transporter and channel
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 13.1
 LDTP16201  B-cell receptor-associated protein 29 (BCAP29) 7.0
 LDTP16069  Peroxisomal membrane protein 2 (PXMP2) 5.4
 LDTP06945  Sigma intracellular receptor 2 (TMEM97) 5.1
 LDTP17641  Solute carrier family 35 member F2 (SLC35F2) 5.0
Other
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 8.8
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 5.9

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587