Probe Name	IA-alkyne					Probe Info
Probe concentration	100 uM
Criteria	Quantification: Probe vs (Probe+Competitor)
Quantitative Method	TMT
Competitor Name	EV-97					Competitor Info
Competitor Concentration	5 uM
In Vivo Experiment Model	Model Type			Cell lysate
	Derived Tissue			Peripheral blood
	Disease Model		Normal
	Model Name		Human normal cell lysate (T cell)

Target ID	Target Name				Binding Sites	Binding Ratio
LDTP12040	Prostaglandin E synthase 2 (PTGES2)				C110	20.0
LDTP03540	Heme oxygenase 2 (HMOX2)				C282	16.1
LDTP13219	GTPase IMAP family member 2 (GIMAP2)				C261	8.7
LDTP10320	tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (TRMT61A)				C204, C209	7.5
LDTP00577	Dihydroxyacetone phosphate acyltransferase (GNPAT)				C54	6.4
LDTP00475	Inhibitor of nuclear factor kappa-B kinase subunit beta (IKBKB)				C464	5.8

Target ID	Target Name				Binding Sites	Binding Ratio
LDTP05511	Cytoskeleton-associated protein 4 (CKAP4)				C100	7.5
LDTP10378	Nuclear envelope pore membrane protein POM 121 (POM121)				C28	4.9

Target ID	Target Name				Binding Sites	Binding Ratio
LDTP11193	Metastasis-associated protein MTA3 (MTA3)				C532	5.5

Target ID	Target Name				Binding Sites	Binding Ratio
LDTP08248	NLR family member X1 (NLRX1)				C331	18.9
LDTP09399	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (PREX1)				C1266	16.5
LDTP13090	UV radiation resistance-associated gene protein (UVRAG)				C239	15.1
LDTP06684	Sister chromatid cohesion protein PDS5 homolog A (PDS5A)				C532	8.8
LDTP07598	BRCA1-associated ATM activator 1 (BRAT1)				C28	8.1
LDTP06281	Condensin complex subunit 1 (NCAPD2)				C767	4.8

1	An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.