Details of the Target

General Information of Target

Target ID LDTP19998
Target Name PI-PLC X domain-containing protein 1 (PLCXD1)
Gene Name PLCXD1
Gene ID 55344
Synonyms
PI-PLC X domain-containing protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAHVLQKPKHSGTHSIVQEFQVPDYVPWQQSKQETKPSTLPPVQQANSLHTSKMKTLTRV
QPVFHFKPTTVVTSCQPKNPRELHRRRKLDPGKMHAKIWLMKTSLRSGRAALRELRSREN
FLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWE
EKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQ
QDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQ
RFREIIDQFEENMPVLRAEVEELQAQTREPREVIFEDVLLRRPKCTPDMDVILNIPVEEP
LPF
Target Bioclass
Other
Subcellular location
Cytoplasm
Uniprot ID
Q9NUJ7
Ensemble ID
ENST00000381657.8
HGNC ID
HGNC:23148

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 6 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		N.A.  LDD0241  [1]
DBIA
 Probe Info  		C288(1.67)  LDD3330  [2]
IA-alkyne
 Probe Info  		N.A.  LDD0167  [3]
TFBX
 Probe Info  		N.A.  LDD0148  [4]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [5]
W1
 Probe Info  		N.A.  LDD0236  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 PaTu 8988t C28(0.83)  LDD1093  [6]
 LDCM0215  AC10 HEK-293T C288(1.02); C153(1.06); C170(1.14)  LDD1508  [7]
 LDCM0216  AC100 PaTu 8988t C28(0.87)  LDD1095  [6]
 LDCM0217  AC101 PaTu 8988t C28(0.86)  LDD1096  [6]
 LDCM0218  AC102 PaTu 8988t C28(0.73)  LDD1097  [6]
 LDCM0219  AC103 PaTu 8988t C28(0.97)  LDD1098  [6]
 LDCM0220  AC104 PaTu 8988t C28(0.73)  LDD1099  [6]
 LDCM0221  AC105 PaTu 8988t C28(0.60)  LDD1100  [6]
 LDCM0222  AC106 PaTu 8988t C28(0.90)  LDD1101  [6]
 LDCM0223  AC107 PaTu 8988t C28(0.89)  LDD1102  [6]
 LDCM0224  AC108 PaTu 8988t C28(0.74)  LDD1103  [6]
 LDCM0225  AC109 PaTu 8988t C28(0.94)  LDD1104  [6]
 LDCM0226  AC11 HEK-293T C288(0.97); C170(1.12); C180(0.98)  LDD1509  [7]
 LDCM0227  AC110 PaTu 8988t C28(0.81)  LDD1106  [6]
 LDCM0228  AC111 PaTu 8988t C28(0.86)  LDD1107  [6]
 LDCM0229  AC112 PaTu 8988t C28(0.83)  LDD1108  [6]
 LDCM0230  AC113 PaTu 8988t C28(0.95)  LDD1109  [6]
 LDCM0231  AC114 PaTu 8988t C28(1.01)  LDD1110  [6]
 LDCM0232  AC115 PaTu 8988t C28(1.12)  LDD1111  [6]
 LDCM0233  AC116 PaTu 8988t C28(1.11)  LDD1112  [6]
 LDCM0234  AC117 PaTu 8988t C28(1.51)  LDD1113  [6]
 LDCM0235  AC118 PaTu 8988t C28(1.12)  LDD1114  [6]
 LDCM0236  AC119 PaTu 8988t C28(1.02)  LDD1115  [6]
 LDCM0237  AC12 HEK-293T C288(1.08); C153(1.06); C170(0.94)  LDD1510  [7]
 LDCM0238  AC120 PaTu 8988t C28(0.90)  LDD1117  [6]
 LDCM0239  AC121 PaTu 8988t C28(0.94)  LDD1118  [6]
 LDCM0240  AC122 PaTu 8988t C28(0.95)  LDD1119  [6]
 LDCM0241  AC123 PaTu 8988t C28(0.83)  LDD1120  [6]
 LDCM0242  AC124 PaTu 8988t C28(1.07)  LDD1121  [6]
 LDCM0243  AC125 PaTu 8988t C28(1.14)  LDD1122  [6]
 LDCM0244  AC126 PaTu 8988t C28(1.05)  LDD1123  [6]
 LDCM0245  AC127 PaTu 8988t C28(0.81)  LDD1124  [6]
 LDCM0259  AC14 HEK-293T C288(0.94); C153(1.05); C170(1.08)  LDD1512  [7]
 LDCM0270  AC15 HEK-293T C288(0.95); C75(1.22); C153(1.03); C170(0.87)  LDD1513  [7]
 LDCM0276  AC17 HEK-293T C180(0.88)  LDD0874  [6]
 LDCM0277  AC18 HEK-293T C180(0.78)  LDD0875  [6]
 LDCM0278  AC19 HEK-293T C180(0.85)  LDD0876  [6]
 LDCM0279  AC2 PaTu 8988t C28(0.84)  LDD1158  [6]
 LDCM0280  AC20 HEK-293T C180(0.85)  LDD0878  [6]
 LDCM0281  AC21 HEK-293T C180(0.78)  LDD0879  [6]
 LDCM0282  AC22 HEK-293T C180(0.81)  LDD0880  [6]
 LDCM0283  AC23 HEK-293T C180(0.84)  LDD0881  [6]
 LDCM0284  AC24 HEK-293T C180(0.85)  LDD0882  [6]
 LDCM0285  AC25 HEK-293T C180(0.83)  LDD0883  [6]
 LDCM0286  AC26 HEK-293T C180(0.87)  LDD0884  [6]
 LDCM0287  AC27 HEK-293T C180(0.94)  LDD0885  [6]
 LDCM0288  AC28 HEK-293T C180(0.97)  LDD0886  [6]
 LDCM0289  AC29 HEK-293T C180(0.84)  LDD0887  [6]
 LDCM0290  AC3 PaTu 8988t C28(0.82)  LDD1169  [6]
 LDCM0291  AC30 HEK-293T C180(0.82)  LDD0889  [6]
 LDCM0292  AC31 HEK-293T C180(1.01)  LDD0890  [6]
 LDCM0293  AC32 HEK-293T C180(0.94)  LDD0891  [6]
 LDCM0294  AC33 HEK-293T C180(0.89)  LDD0892  [6]
 LDCM0295  AC34 HEK-293T C180(0.83)  LDD0893  [6]
 LDCM0296  AC35 HEK-293T C288(1.03); C170(1.06); C180(1.06)  LDD1535  [7]
 LDCM0297  AC36 HEK-293T C288(1.01); C153(1.02); C170(0.88)  LDD1536  [7]
 LDCM0298  AC37 HEK-293T C288(1.05); C75(1.09); C153(0.90); C170(1.04)  LDD1537  [7]
 LDCM0299  AC38 HEK-293T C288(1.01); C153(1.02); C170(1.22)  LDD1538  [7]
 LDCM0300  AC39 HEK-293T C288(0.98); C75(1.17); C153(1.14); C170(0.94)  LDD1539  [7]
 LDCM0301  AC4 PaTu 8988t C28(0.83)  LDD1180  [6]
 LDCM0302  AC40 HEK-293T C288(1.01); C75(1.26); C153(1.09); C170(1.24)  LDD1541  [7]
 LDCM0303  AC41 HEK-293T C288(0.80); C75(1.26); C153(1.05); C170(1.04)  LDD1542  [7]
 LDCM0304  AC42 HEK-293T C288(1.10); C153(0.98); C170(1.32)  LDD1543  [7]
 LDCM0305  AC43 HEK-293T C288(1.05); C170(1.00); C180(1.08)  LDD1544  [7]
 LDCM0306  AC44 HEK-293T C288(1.09); C153(0.96); C170(0.91)  LDD1545  [7]
 LDCM0307  AC45 HEK-293T C288(1.00); C75(1.15); C153(1.11); C170(1.11)  LDD1546  [7]
 LDCM0308  AC46 HEK-293T C180(1.03)  LDD0906  [6]
 LDCM0309  AC47 HEK-293T C180(1.01)  LDD0907  [6]
 LDCM0310  AC48 HEK-293T C180(0.95)  LDD0908  [6]
 LDCM0311  AC49 HEK-293T C180(0.85)  LDD0909  [6]
 LDCM0312  AC5 PaTu 8988t C28(0.79)  LDD1191  [6]
 LDCM0313  AC50 HEK-293T C180(0.92)  LDD0911  [6]
 LDCM0314  AC51 HEK-293T C180(0.91)  LDD0912  [6]
 LDCM0315  AC52 HEK-293T C180(0.88)  LDD0913  [6]
 LDCM0316  AC53 HEK-293T C180(0.95)  LDD0914  [6]
 LDCM0317  AC54 HEK-293T C180(0.89)  LDD0915  [6]
 LDCM0318  AC55 HEK-293T C180(0.87)  LDD0916  [6]
 LDCM0319  AC56 HEK-293T C180(0.87)  LDD0917  [6]
 LDCM0320  AC57 HEK-293T C288(0.93); C75(0.96); C153(0.95); C170(0.89)  LDD1559  [7]
 LDCM0321  AC58 HEK-293T C288(1.12); C153(1.11); C170(0.94)  LDD1560  [7]
 LDCM0322  AC59 HEK-293T C288(0.93); C170(1.03); C180(0.99)  LDD1561  [7]
 LDCM0323  AC6 HEK-293T C288(0.95); C153(1.00); C170(1.09)  LDD1562  [7]
 LDCM0324  AC60 HEK-293T C288(1.10); C153(1.12); C170(0.85)  LDD1563  [7]
 LDCM0325  AC61 HEK-293T C288(1.07); C75(1.00); C153(1.00); C170(1.10)  LDD1564  [7]
 LDCM0326  AC62 HEK-293T C288(1.03); C153(1.05); C170(1.13)  LDD1565  [7]
 LDCM0327  AC63 HEK-293T C288(0.93); C75(0.98); C153(1.04); C170(1.08)  LDD1566  [7]
 LDCM0328  AC64 HEK-293T C288(1.01); C75(1.15); C153(0.98); C170(1.28)  LDD1567  [7]
 LDCM0334  AC7 HEK-293T C288(0.95); C75(1.14); C153(0.98); C170(1.03)  LDD1568  [7]
 LDCM0345  AC8 HEK-293T C288(1.03); C75(1.08); C153(1.03); C170(1.37)  LDD1569  [7]
 LDCM0349  AC83 HEK-293T C180(0.89)  LDD0947  [6]
 LDCM0350  AC84 HEK-293T C180(0.87)  LDD0948  [6]
 LDCM0351  AC85 HEK-293T C180(1.00)  LDD0949  [6]
 LDCM0352  AC86 HEK-293T C180(0.96)  LDD0950  [6]
 LDCM0353  AC87 HEK-293T C180(0.91)  LDD0951  [6]
 LDCM0354  AC88 HEK-293T C180(0.84)  LDD0952  [6]
 LDCM0355  AC89 HEK-293T C180(0.96)  LDD0953  [6]
 LDCM0357  AC90 HEK-293T C180(0.85)  LDD0955  [6]
 LDCM0358  AC91 HEK-293T C180(0.87)  LDD0956  [6]
 LDCM0359  AC92 HEK-293T C180(0.91)  LDD0957  [6]
 LDCM0360  AC93 HEK-293T C180(1.05)  LDD0958  [6]
 LDCM0361  AC94 HEK-293T C180(0.96)  LDD0959  [6]
 LDCM0362  AC95 HEK-293T C180(0.96)  LDD0960  [6]
 LDCM0363  AC96 HEK-293T C180(0.95)  LDD0961  [6]
 LDCM0364  AC97 HEK-293T C180(0.93)  LDD0962  [6]
 LDCM0365  AC98 PaTu 8988t C28(1.05)  LDD1244  [6]
 LDCM0366  AC99 PaTu 8988t C28(0.85)  LDD1245  [6]
 LDCM0248  AKOS034007472 HEK-293T C288(1.01); C75(1.17); C153(1.09); C170(1.06)  LDD1511  [7]
 LDCM0356  AKOS034007680 HEK-293T C288(0.80); C75(1.09); C153(1.06); C170(0.90)  LDD1570  [7]
 LDCM0275  AKOS034007705 HEK-293T C288(0.99); C75(1.39); C153(1.15); C170(1.08)  LDD1514  [7]
 LDCM0367  CL1 PaTu 8988t C28(0.96)  LDD1246  [6]
 LDCM0368  CL10 PaTu 8988t C28(1.54)  LDD1247  [6]
 LDCM0369  CL100 PaTu 8988t C28(0.68)  LDD1248  [6]
 LDCM0370  CL101 HEK-293T C288(1.04); C75(0.97); C170(1.19)  LDD1574  [7]
 LDCM0371  CL102 HEK-293T C288(0.99); C75(1.45); C170(1.02)  LDD1575  [7]
 LDCM0372  CL103 HEK-293T C288(0.99); C75(0.96); C153(1.11); C170(1.05)  LDD1576  [7]
 LDCM0373  CL104 HEK-293T C288(0.92); C153(0.97)  LDD1577  [7]
 LDCM0374  CL105 HEK-293T C180(0.94)  LDD0972  [6]
 LDCM0375  CL106 HEK-293T C180(0.89)  LDD0973  [6]
 LDCM0376  CL107 HEK-293T C180(0.88)  LDD0974  [6]
 LDCM0377  CL108 HEK-293T C180(0.85)  LDD0975  [6]
 LDCM0378  CL109 HEK-293T C180(0.85)  LDD0976  [6]
 LDCM0379  CL11 PaTu 8988t C28(0.87)  LDD1258  [6]
 LDCM0380  CL110 HEK-293T C180(0.86)  LDD0978  [6]
 LDCM0381  CL111 HEK-293T C180(0.86)  LDD0979  [6]
 LDCM0382  CL112 HEK-293T C180(0.76)  LDD0980  [6]
 LDCM0383  CL113 HEK-293T C180(0.91)  LDD0981  [6]
 LDCM0384  CL114 HEK-293T C180(0.88)  LDD0982  [6]
 LDCM0385  CL115 HEK-293T C180(0.77)  LDD0983  [6]
 LDCM0386  CL116 HEK-293T C180(0.81)  LDD0984  [6]
 LDCM0387  CL117 HEK-293T C288(1.08); C75(1.02); C170(1.00)  LDD1591  [7]
 LDCM0388  CL118 HEK-293T C288(1.02); C75(1.02); C170(0.95)  LDD1592  [7]
 LDCM0389  CL119 HEK-293T C288(1.01); C75(1.14); C153(1.17); C170(0.98)  LDD1593  [7]
 LDCM0390  CL12 PaTu 8988t C28(1.15)  LDD1269  [6]
 LDCM0391  CL120 HEK-293T C288(1.11); C153(1.04)  LDD1595  [7]
 LDCM0392  CL121 HEK-293T C180(0.90)  LDD0990  [6]
 LDCM0393  CL122 HEK-293T C180(0.92)  LDD0991  [6]
 LDCM0394  CL123 HEK-293T C180(0.93)  LDD0992  [6]
 LDCM0395  CL124 HEK-293T C180(0.87)  LDD0993  [6]
 LDCM0396  CL125 HEK-293T C288(0.94); C75(0.75); C170(1.12)  LDD1600  [7]
 LDCM0397  CL126 HEK-293T C288(1.00); C75(1.43); C170(0.96)  LDD1601  [7]
 LDCM0398  CL127 HEK-293T C288(1.07); C75(1.17); C153(1.02); C170(1.15)  LDD1602  [7]
 LDCM0399  CL128 HEK-293T C288(1.05); C153(1.06)  LDD1603  [7]
 LDCM0400  CL13 PaTu 8988t C28(1.91)  LDD1279  [6]
 LDCM0401  CL14 PaTu 8988t C28(1.63)  LDD1280  [6]
 LDCM0402  CL15 PaTu 8988t C28(1.18)  LDD1281  [6]
 LDCM0403  CL16 HEK-293T C288(0.90); C153(0.99)  LDD1607  [7]
 LDCM0404  CL17 HEK-293T C288(0.84); C75(2.39); C153(1.05); C170(0.88)  LDD1608  [7]
 LDCM0405  CL18 HEK-293T C288(1.07); C153(1.05); C170(1.08)  LDD1609  [7]
 LDCM0406  CL19 HEK-293T C288(0.95); C170(1.04); C180(0.94)  LDD1610  [7]
 LDCM0407  CL2 PaTu 8988t C28(0.91)  LDD1286  [6]
 LDCM0408  CL20 HEK-293T C288(1.07); C153(0.99); C170(0.97)  LDD1612  [7]
 LDCM0409  CL21 HEK-293T C288(1.15); C75(2.81); C153(1.08); C170(1.43)  LDD1613  [7]
 LDCM0410  CL22 HEK-293T C288(1.06); C153(1.24); C170(1.27)  LDD1614  [7]
 LDCM0411  CL23 HEK-293T C288(1.04); C75(2.01); C153(1.12); C170(1.08)  LDD1615  [7]
 LDCM0412  CL24 HEK-293T C288(1.11); C75(2.35); C153(1.22); C170(1.12)  LDD1616  [7]
 LDCM0413  CL25 HEK-293T C288(1.11); C75(2.07); C170(0.76)  LDD1617  [7]
 LDCM0414  CL26 HEK-293T C288(0.99); C75(1.01); C170(0.93)  LDD1618  [7]
 LDCM0415  CL27 HEK-293T C288(1.05); C75(0.99); C153(1.07); C170(1.18)  LDD1619  [7]
 LDCM0416  CL28 HEK-293T C288(1.03); C153(1.05)  LDD1620  [7]
 LDCM0417  CL29 HEK-293T C288(0.78); C75(1.27); C153(1.02); C170(1.04)  LDD1621  [7]
 LDCM0418  CL3 PaTu 8988t C28(1.24)  LDD1297  [6]
 LDCM0419  CL30 HEK-293T C288(1.10); C153(0.97); C170(0.99)  LDD1623  [7]
 LDCM0420  CL31 PaTu 8988t C28(1.12)  LDD1299  [6]
 LDCM0421  CL32 PaTu 8988t C28(1.41)  LDD1300  [6]
 LDCM0422  CL33 PaTu 8988t C28(1.32)  LDD1301  [6]
 LDCM0423  CL34 PaTu 8988t C28(1.20)  LDD1302  [6]
 LDCM0424  CL35 PaTu 8988t C28(1.45)  LDD1303  [6]
 LDCM0425  CL36 PaTu 8988t C28(0.67)  LDD1304  [6]
 LDCM0426  CL37 PaTu 8988t C28(1.35)  LDD1305  [6]
 LDCM0428  CL39 PaTu 8988t C28(1.30)  LDD1307  [6]
 LDCM0429  CL4 PaTu 8988t C28(1.12)  LDD1308  [6]
 LDCM0430  CL40 PaTu 8988t C28(1.20)  LDD1309  [6]
 LDCM0431  CL41 PaTu 8988t C28(1.16)  LDD1310  [6]
 LDCM0432  CL42 PaTu 8988t C28(1.20)  LDD1311  [6]
 LDCM0433  CL43 PaTu 8988t C28(1.33)  LDD1312  [6]
 LDCM0434  CL44 PaTu 8988t C28(1.68)  LDD1313  [6]
 LDCM0435  CL45 PaTu 8988t C28(1.96)  LDD1314  [6]
 LDCM0436  CL46 HEK-293T C288(1.04); C153(1.22); C170(1.08)  LDD1640  [7]
 LDCM0437  CL47 HEK-293T C288(1.02); C75(2.34); C153(1.08); C170(1.06)  LDD1641  [7]
 LDCM0438  CL48 HEK-293T C288(1.11); C75(2.00); C153(1.27); C170(1.28)  LDD1642  [7]
 LDCM0439  CL49 HEK-293T C288(1.08); C75(0.83); C170(1.21)  LDD1643  [7]
 LDCM0440  CL5 PaTu 8988t C28(1.91)  LDD1319  [6]
 LDCM0441  CL50 HEK-293T C288(0.97); C75(1.14); C170(1.01)  LDD1645  [7]
 LDCM0443  CL52 HEK-293T C288(0.89); C153(1.12)  LDD1646  [7]
 LDCM0444  CL53 HEK-293T C288(1.05); C75(1.45); C153(1.06); C170(0.90)  LDD1647  [7]
 LDCM0445  CL54 HEK-293T C288(1.05); C153(1.20); C170(0.97)  LDD1648  [7]
 LDCM0446  CL55 HEK-293T C288(0.95); C170(0.97); C180(1.00)  LDD1649  [7]
 LDCM0447  CL56 HEK-293T C288(1.12); C153(1.12); C170(0.96)  LDD1650  [7]
 LDCM0448  CL57 HEK-293T C288(1.14); C75(2.11); C153(1.01); C170(1.04)  LDD1651  [7]
 LDCM0449  CL58 HEK-293T C288(1.04); C153(1.21); C170(1.19)  LDD1652  [7]
 LDCM0450  CL59 HEK-293T C288(1.27); C75(1.90); C153(1.15); C170(1.12)  LDD1653  [7]
 LDCM0451  CL6 PaTu 8988t C28(1.22)  LDD1330  [6]
 LDCM0452  CL60 HEK-293T C288(1.12); C75(2.12); C153(1.14); C170(1.32)  LDD1655  [7]
 LDCM0453  CL61 PaTu 8988t C28(0.86)  LDD1332  [6]
 LDCM0454  CL62 PaTu 8988t C28(0.96)  LDD1333  [6]
 LDCM0455  CL63 PaTu 8988t C28(1.00)  LDD1334  [6]
 LDCM0456  CL64 PaTu 8988t C28(1.23)  LDD1335  [6]
 LDCM0457  CL65 PaTu 8988t C28(1.10)  LDD1336  [6]
 LDCM0458  CL66 PaTu 8988t C28(1.12)  LDD1337  [6]
 LDCM0459  CL67 PaTu 8988t C28(1.27)  LDD1338  [6]
 LDCM0460  CL68 PaTu 8988t C28(1.52)  LDD1339  [6]
 LDCM0461  CL69 PaTu 8988t C28(1.26)  LDD1340  [6]
 LDCM0462  CL7 PaTu 8988t C28(1.30)  LDD1341  [6]
 LDCM0463  CL70 PaTu 8988t C28(1.36)  LDD1342  [6]
 LDCM0464  CL71 PaTu 8988t C28(0.96)  LDD1343  [6]
 LDCM0465  CL72 PaTu 8988t C28(1.06)  LDD1344  [6]
 LDCM0466  CL73 PaTu 8988t C28(1.38)  LDD1345  [6]
 LDCM0467  CL74 PaTu 8988t C28(1.08)  LDD1346  [6]
 LDCM0469  CL76 PaTu 8988t C28(0.94)  LDD1348  [6]
 LDCM0470  CL77 PaTu 8988t C28(0.91)  LDD1349  [6]
 LDCM0471  CL78 PaTu 8988t C28(1.26)  LDD1350  [6]
 LDCM0472  CL79 PaTu 8988t C28(1.16)  LDD1351  [6]
 LDCM0473  CL8 PaTu 8988t C28(1.36)  LDD1352  [6]
 LDCM0474  CL80 PaTu 8988t C28(1.25)  LDD1353  [6]
 LDCM0475  CL81 PaTu 8988t C28(1.30)  LDD1354  [6]
 LDCM0476  CL82 PaTu 8988t C28(1.26)  LDD1355  [6]
 LDCM0477  CL83 PaTu 8988t C28(1.37)  LDD1356  [6]
 LDCM0478  CL84 PaTu 8988t C28(1.14)  LDD1357  [6]
 LDCM0479  CL85 PaTu 8988t C28(1.06)  LDD1358  [6]
 LDCM0480  CL86 PaTu 8988t C28(1.06)  LDD1359  [6]
 LDCM0481  CL87 PaTu 8988t C28(1.22)  LDD1360  [6]
 LDCM0482  CL88 PaTu 8988t C28(1.26)  LDD1361  [6]
 LDCM0483  CL89 PaTu 8988t C28(1.04)  LDD1362  [6]
 LDCM0484  CL9 PaTu 8988t C28(1.23)  LDD1363  [6]
 LDCM0485  CL90 PaTu 8988t C28(1.33)  LDD1364  [6]
 LDCM0486  CL91 PaTu 8988t C28(0.66)  LDD1365  [6]
 LDCM0487  CL92 PaTu 8988t C28(0.78)  LDD1366  [6]
 LDCM0488  CL93 PaTu 8988t C28(0.68)  LDD1367  [6]
 LDCM0489  CL94 PaTu 8988t C28(0.75)  LDD1368  [6]
 LDCM0490  CL95 PaTu 8988t C28(0.86)  LDD1369  [6]
 LDCM0491  CL96 PaTu 8988t C28(0.62)  LDD1370  [6]
 LDCM0492  CL97 PaTu 8988t C28(0.74)  LDD1371  [6]
 LDCM0493  CL98 PaTu 8988t C28(0.88)  LDD1372  [6]
 LDCM0494  CL99 PaTu 8988t C28(0.76)  LDD1373  [6]
 LDCM0495  E2913 HEK-293T C288(1.11); C75(0.95); C153(1.02); C170(1.04)  LDD1698  [7]
 LDCM0468  Fragment33 PaTu 8988t C28(1.08)  LDD1347  [6]
 LDCM0427  Fragment51 PaTu 8988t C28(1.23)  LDD1306  [6]
 LDCM0022  KB02 HEK-293T C288(0.98)  LDD1492  [7]
 LDCM0023  KB03 HEK-293T C288(1.00)  LDD1497  [7]
 LDCM0024  KB05 MIA PaCa-2 C288(1.67)  LDD3330  [2]

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
4 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
5 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
6 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
7 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402