Details of the Target

General Information of Target

Target ID LDTP18904
Target Name Uncharacterized protein CXorf49 (CXorf49; CXorf49B)
Gene Name CXorf49; CXorf49B
Gene ID 100130361
Synonyms
; Uncharacterized protein CXorf49
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MMARRDPKSWAKRLVRAQTLQKQRRAPVGPRSPPPDEEDPRLKCKNCGAFGHTARSTRCP
MKCWKAALVPATLGKKEGKENLKPWKPRAEANPGPLNKDKGEKEERPRQQDPQRKALLHM
FSGKPPEKPLPNGKGSTESSDYLRVASGPMPVHTTSKRPRLDPVLADRSATEMSGRGSVL
ASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSRPEGGCREV
PQAASKTHGLLQAARPQAQDKRPAVTPQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQA
CLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVD
RQPPHSRPCLPTAQACTMSHHPAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKP
GAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE
Target Bioclass
Other
Uniprot ID
A8MYA2
Ensemble ID
ENST00000535490.3
HGNC ID
HGNC:30891

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C340(1.29)  LDD0533  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0216  AC100 HCT 116 C340(1.29)  LDD0533  [1]
 LDCM0217  AC101 HCT 116 C340(1.29)  LDD0534  [1]
 LDCM0218  AC102 HCT 116 C340(1.00)  LDD0535  [1]
 LDCM0219  AC103 HCT 116 C340(1.51)  LDD0536  [1]
 LDCM0220  AC104 HCT 116 C340(1.22)  LDD0537  [1]
 LDCM0221  AC105 HCT 116 C340(1.17)  LDD0538  [1]
 LDCM0222  AC106 HCT 116 C340(0.98)  LDD0539  [1]
 LDCM0223  AC107 HCT 116 C340(0.86)  LDD0540  [1]
 LDCM0224  AC108 HCT 116 C340(1.06)  LDD0541  [1]
 LDCM0225  AC109 HCT 116 C340(1.23)  LDD0542  [1]
 LDCM0227  AC110 HCT 116 C340(0.86)  LDD0544  [1]
 LDCM0228  AC111 HCT 116 C340(0.80)  LDD0545  [1]
 LDCM0229  AC112 HCT 116 C340(0.93)  LDD0546  [1]
 LDCM0296  AC35 HCT 116 C340(1.03)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C340(1.39)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C340(1.06)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C340(1.43)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C340(0.98)  LDD0617  [1]
 LDCM0302  AC40 HCT 116 C340(1.20)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C340(0.97)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C340(0.99)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C340(1.20)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C340(0.68)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C340(0.78)  LDD0624  [1]
 LDCM0320  AC57 HCT 116 C340(1.08)  LDD0637  [1]
 LDCM0321  AC58 HCT 116 C340(0.84)  LDD0638  [1]
 LDCM0322  AC59 HCT 116 C340(0.94)  LDD0639  [1]
 LDCM0324  AC60 HCT 116 C340(1.08)  LDD0641  [1]
 LDCM0325  AC61 HCT 116 C340(1.03)  LDD0642  [1]
 LDCM0326  AC62 HCT 116 C340(1.02)  LDD0643  [1]
 LDCM0327  AC63 HCT 116 C340(0.92)  LDD0644  [1]
 LDCM0328  AC64 HCT 116 C340(0.96)  LDD0645  [1]
 LDCM0329  AC65 HCT 116 C340(1.00)  LDD0646  [1]
 LDCM0330  AC66 HCT 116 C340(1.05)  LDD0647  [1]
 LDCM0331  AC67 HCT 116 C340(1.09)  LDD0648  [1]
 LDCM0349  AC83 HCT 116 C340(1.10)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C340(1.07)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C340(1.14)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C340(0.93)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C340(0.93)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C340(0.84)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C340(1.03)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C340(0.81)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C340(1.09)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C340(0.95)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C340(0.94)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C340(1.47)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C340(0.89)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C340(0.90)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C340(1.10)  LDD0681  [1]
 LDCM0365  AC98 HCT 116 C340(1.78)  LDD0682  [1]
 LDCM0366  AC99 HCT 116 C340(1.51)  LDD0683  [1]
 LDCM0387  CL117 HCT 116 C340(0.79)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C340(1.21)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C340(1.29)  LDD0706  [1]
 LDCM0391  CL120 HCT 116 C340(1.03)  LDD0708  [1]
 LDCM0396  CL125 HCT 116 C340(1.13)  LDD0713  [1]
 LDCM0397  CL126 HCT 116 C340(0.92)  LDD0714  [1]
 LDCM0398  CL127 HCT 116 C340(0.98)  LDD0715  [1]
 LDCM0399  CL128 HCT 116 C340(0.99)  LDD0716  [1]
 LDCM0403  CL16 HCT 116 C340(1.10)  LDD0720  [1]
 LDCM0421  CL32 HCT 116 C340(1.00)  LDD0738  [1]
 LDCM0422  CL33 HCT 116 C340(0.73)  LDD0739  [1]
 LDCM0423  CL34 HCT 116 C340(1.05)  LDD0740  [1]
 LDCM0424  CL35 HCT 116 C340(1.16)  LDD0741  [1]
 LDCM0425  CL36 HCT 116 C340(0.91)  LDD0742  [1]
 LDCM0426  CL37 HCT 116 C340(0.94)  LDD0743  [1]
 LDCM0428  CL39 HCT 116 C340(0.73)  LDD0745  [1]
 LDCM0430  CL40 HCT 116 C340(0.96)  LDD0747  [1]
 LDCM0431  CL41 HCT 116 C340(1.03)  LDD0748  [1]
 LDCM0432  CL42 HCT 116 C340(0.81)  LDD0749  [1]
 LDCM0433  CL43 HCT 116 C340(1.09)  LDD0750  [1]
 LDCM0434  CL44 HCT 116 C340(1.43)  LDD0751  [1]
 LDCM0435  CL45 HCT 116 C340(1.26)  LDD0752  [1]
 LDCM0427  Fragment51 HCT 116 C340(1.05)  LDD0744  [1]
 LDCM0022  KB02 A3-KAW C484(1.44)  LDD2257  [2]
 LDCM0023  KB03 A3-KAW C484(2.46)  LDD2674  [2]
 LDCM0024  KB05 NCI-N87 C487(1.55); C163(1.56); C10(1.91)  LDD3364  [2]

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840