Details of the Target

General Information of Target

Target ID LDTP18168
Target Name Oxidoreductase NAD-binding domain-containing protein 1 (OXNAD1)
Gene Name OXNAD1
Gene ID 92106
Synonyms
Oxidoreductase NAD-binding domain-containing protein 1; EC 1.-.-.-
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MALRHLALLAGLLVGVASKSMENTVTRNSTAVINTQAEGTLSPPGLSSLPVVREWALTHT
AQLPECCVDVVGVNASCPGASLCGPGCYRRWNADGSASCVRCGNGTLPAYNGSECRSFAG
PGAPFPMNRSSGTPGRPHPGAPRVAASLFLGTFFISSGLILSVAGFFYLKRSSKLPRACY
RRNKAPALQPGEAAAMIPPPQSSGNSSCRIPLWGFPSLGQSQGALWVCPQTGLPGSGSRP
PLPGSPGDPPTRQGQGRIWLVPPALDLSWIWPAPPARPPLIPVTSMLFPVPETWGLQERR
THHDRADPQYLLLLEVQLHPRTDAAGLRQALLSSHRFSGAGSGGPKSQPVRKPRYVRRER
PLDRATDPAAFPGEARISNV
Target Bioclass
Enzyme
Uniprot ID
Q96HP4
Ensemble ID
ENST00000285083.10
HGNC ID
HGNC:25128

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 10 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
ONAyne
 Probe Info  		K268(0.75)  LDD0274  [1]
IPM
 Probe Info  		N.A.  LDD0241  [2]
DBIA
 Probe Info  		C69(1.08)  LDD0080  [3]
ATP probe
 Probe Info  		N.A.  LDD0199  [4]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [5]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [5]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [5]
TFBX
 Probe Info  		N.A.  LDD0027  [6]
Acrolein
 Probe Info  		N.A.  LDD0217  [7]
NAIA_5
 Probe Info  		N.A.  LDD2223  [8]
PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STS-1
 Probe Info  		N.A.  LDD0137  [9]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C69(0.90); C283(0.96); C114(1.01); C307(1.05)  LDD1507  [10]
 LDCM0215  AC10 HEK-293T C69(0.98); C283(1.00); C114(0.76); C307(1.06)  LDD1508  [10]
 LDCM0226  AC11 HEK-293T C69(0.87); C241(1.03); C283(1.12); C307(1.15)  LDD1509  [10]
 LDCM0237  AC12 HEK-293T C69(1.12); C283(1.00); C114(1.03); C307(1.05)  LDD1510  [10]
 LDCM0259  AC14 HEK-293T C69(1.39); C241(1.26); C283(0.98); C114(1.15)  LDD1512  [10]
 LDCM0270  AC15 HEK-293T C69(1.12); C283(1.08); C114(0.95); C307(0.99)  LDD1513  [10]
 LDCM0276  AC17 PaTu 8988t C307(0.70)  LDD1155  [3]
 LDCM0277  AC18 PaTu 8988t C307(0.68)  LDD1156  [3]
 LDCM0278  AC19 PaTu 8988t C307(0.72)  LDD1157  [3]
 LDCM0279  AC2 HEK-293T C69(0.93); C283(0.91); C114(0.93); C307(0.98)  LDD1518  [10]
 LDCM0280  AC20 PaTu 8988t C307(0.75)  LDD1159  [3]
 LDCM0281  AC21 PaTu 8988t C307(0.66)  LDD1160  [3]
 LDCM0282  AC22 PaTu 8988t C307(0.70)  LDD1161  [3]
 LDCM0283  AC23 PaTu 8988t C307(0.69)  LDD1162  [3]
 LDCM0284  AC24 PaTu 8988t C307(0.58)  LDD1163  [3]
 LDCM0285  AC25 PaTu 8988t C307(1.52)  LDD1164  [3]
 LDCM0286  AC26 PaTu 8988t C307(1.30)  LDD1165  [3]
 LDCM0287  AC27 PaTu 8988t C307(1.11)  LDD1166  [3]
 LDCM0288  AC28 PaTu 8988t C307(1.15)  LDD1167  [3]
 LDCM0289  AC29 PaTu 8988t C307(1.21)  LDD1168  [3]
 LDCM0290  AC3 HEK-293T C69(0.86); C241(1.05); C283(1.09); C307(1.02)  LDD1529  [10]
 LDCM0291  AC30 PaTu 8988t C307(1.19)  LDD1170  [3]
 LDCM0292  AC31 PaTu 8988t C307(1.56)  LDD1171  [3]
 LDCM0293  AC32 PaTu 8988t C307(1.08)  LDD1172  [3]
 LDCM0294  AC33 PaTu 8988t C307(0.93)  LDD1173  [3]
 LDCM0295  AC34 PaTu 8988t C307(0.83)  LDD1174  [3]
 LDCM0296  AC35 HEK-293T C69(1.02); C241(1.05); C283(1.04); C307(1.14)  LDD1535  [10]
 LDCM0297  AC36 HEK-293T C69(1.08); C283(1.11); C114(0.97); C307(1.06)  LDD1536  [10]
 LDCM0298  AC37 HEK-293T C69(0.85); C283(0.88); C114(0.97); C307(0.94)  LDD1537  [10]
 LDCM0299  AC38 HEK-293T C69(0.95); C241(1.29); C283(0.95); C114(0.86)  LDD1538  [10]
 LDCM0300  AC39 HEK-293T C69(1.37); C283(1.12); C114(1.00); C307(0.92)  LDD1539  [10]
 LDCM0301  AC4 HEK-293T C69(1.08); C283(1.26); C114(1.11); C307(1.05)  LDD1540  [10]
 LDCM0302  AC40 HEK-293T C69(1.02); C283(0.90); C307(1.11)  LDD1541  [10]
 LDCM0303  AC41 HEK-293T C69(0.91); C283(0.93); C114(1.02); C307(1.12)  LDD1542  [10]
 LDCM0304  AC42 HEK-293T C69(0.85); C283(1.00); C114(1.03); C307(1.02)  LDD1543  [10]
 LDCM0305  AC43 HEK-293T C69(1.07); C241(1.17); C283(1.11); C307(1.14)  LDD1544  [10]
 LDCM0306  AC44 HEK-293T C69(1.15); C283(0.92); C114(1.06); C307(1.05)  LDD1545  [10]
 LDCM0307  AC45 HEK-293T C69(0.87); C283(0.91); C114(1.07); C307(1.05)  LDD1546  [10]
 LDCM0308  AC46 PaTu 8988t C307(1.36)  LDD1187  [3]
 LDCM0309  AC47 PaTu 8988t C307(1.26)  LDD1188  [3]
 LDCM0310  AC48 PaTu 8988t C307(1.30)  LDD1189  [3]
 LDCM0311  AC49 PaTu 8988t C307(0.98)  LDD1190  [3]
 LDCM0312  AC5 HEK-293T C69(0.85); C283(0.96); C114(1.00); C307(1.01)  LDD1551  [10]
 LDCM0313  AC50 PaTu 8988t C307(0.98)  LDD1192  [3]
 LDCM0314  AC51 PaTu 8988t C307(0.24)  LDD1193  [3]
 LDCM0315  AC52 PaTu 8988t C307(1.08)  LDD1194  [3]
 LDCM0316  AC53 PaTu 8988t C307(0.92)  LDD1195  [3]
 LDCM0317  AC54 PaTu 8988t C307(0.94)  LDD1196  [3]
 LDCM0318  AC55 PaTu 8988t C307(0.95)  LDD1197  [3]
 LDCM0319  AC56 PaTu 8988t C307(0.79)  LDD1198  [3]
 LDCM0320  AC57 HEK-293T C69(0.94); C283(0.91); C114(0.83); C307(0.98)  LDD1559  [10]
 LDCM0321  AC58 HEK-293T C69(0.92); C283(1.10); C114(1.05); C307(1.13)  LDD1560  [10]
 LDCM0322  AC59 HEK-293T C69(0.97); C241(0.95); C283(1.15); C307(1.12)  LDD1561  [10]
 LDCM0323  AC6 HEK-293T C69(1.15); C241(1.21); C283(0.94); C114(0.93)  LDD1562  [10]
 LDCM0324  AC60 HEK-293T C69(1.10); C283(1.40); C114(0.96); C307(0.99)  LDD1563  [10]
 LDCM0325  AC61 HEK-293T C69(1.10); C283(1.06); C114(1.07); C307(0.97)  LDD1564  [10]
 LDCM0326  AC62 HEK-293T C69(1.18); C241(1.18); C283(1.04); C114(0.94)  LDD1565  [10]
 LDCM0327  AC63 HEK-293T C69(1.13); C283(1.08); C114(1.10); C307(1.01)  LDD1566  [10]
 LDCM0328  AC64 HEK-293T C69(1.04); C283(1.02); C307(0.97)  LDD1567  [10]
 LDCM0334  AC7 HEK-293T C69(0.87); C283(0.94); C114(1.03); C307(0.92)  LDD1568  [10]
 LDCM0345  AC8 HEK-293T C69(1.00); C283(1.03); C307(0.96)  LDD1569  [10]
 LDCM0248  AKOS034007472 HEK-293T C69(0.88); C283(0.97); C114(1.04); C307(0.95)  LDD1511  [10]
 LDCM0356  AKOS034007680 HEK-293T C69(0.85); C283(1.09); C114(1.06); C307(1.01)  LDD1570  [10]
 LDCM0275  AKOS034007705 HEK-293T C69(1.09); C283(1.06); C307(1.00)  LDD1514  [10]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [7]
 LDCM0367  CL1 HEK-293T C69(1.04); C241(1.17); C283(0.94); C114(0.57)  LDD1571  [10]
 LDCM0368  CL10 HEK-293T C69(0.88); C241(1.34); C283(0.59); C114(0.77)  LDD1572  [10]
 LDCM0369  CL100 HEK-293T C69(0.98); C241(1.09); C283(1.13); C307(1.02)  LDD1573  [10]
 LDCM0370  CL101 HEK-293T C69(0.90); C241(1.09); C283(0.94); C114(0.93)  LDD1574  [10]
 LDCM0371  CL102 HEK-293T C69(0.82); C241(1.01); C283(0.78); C307(0.96)  LDD1575  [10]
 LDCM0372  CL103 HEK-293T C69(1.00); C241(1.22); C283(0.91); C114(1.09)  LDD1576  [10]
 LDCM0373  CL104 HEK-293T C69(0.92); C241(1.09); C283(1.08); C307(1.04)  LDD1577  [10]
 LDCM0374  CL105 PaTu 8988t C307(1.04)  LDD1253  [3]
 LDCM0375  CL106 PaTu 8988t C307(0.72)  LDD1254  [3]
 LDCM0376  CL107 PaTu 8988t C307(0.87)  LDD1255  [3]
 LDCM0377  CL108 PaTu 8988t C307(0.73)  LDD1256  [3]
 LDCM0378  CL109 PaTu 8988t C307(0.77)  LDD1257  [3]
 LDCM0379  CL11 HEK-293T C69(1.10); C283(0.91); C114(1.01); C307(1.11)  LDD1583  [10]
 LDCM0380  CL110 PaTu 8988t C307(0.73)  LDD1259  [3]
 LDCM0381  CL111 PaTu 8988t C307(0.62)  LDD1260  [3]
 LDCM0382  CL112 PaTu 8988t C307(1.32)  LDD1261  [3]
 LDCM0383  CL113 PaTu 8988t C307(1.60)  LDD1262  [3]
 LDCM0384  CL114 PaTu 8988t C307(1.34)  LDD1263  [3]
 LDCM0385  CL115 PaTu 8988t C307(1.57)  LDD1264  [3]
 LDCM0386  CL116 PaTu 8988t C307(0.98)  LDD1265  [3]
 LDCM0387  CL117 HEK-293T C69(1.02); C241(1.20); C283(1.10); C114(1.03)  LDD1591  [10]
 LDCM0388  CL118 HEK-293T C69(1.15); C241(1.10); C283(0.81); C307(0.99)  LDD1592  [10]
 LDCM0389  CL119 HEK-293T C69(1.02); C241(1.16); C283(1.04); C114(0.87)  LDD1593  [10]
 LDCM0390  CL12 HEK-293T C69(1.14); C283(1.11); C307(1.00)  LDD1594  [10]
 LDCM0391  CL120 HEK-293T C69(1.00); C241(1.05); C283(1.29); C307(1.03)  LDD1595  [10]
 LDCM0392  CL121 PaTu 8988t C307(1.09)  LDD1271  [3]
 LDCM0393  CL122 PaTu 8988t C307(1.20)  LDD1272  [3]
 LDCM0394  CL123 PaTu 8988t C307(1.23)  LDD1273  [3]
 LDCM0395  CL124 PaTu 8988t C307(1.05)  LDD1274  [3]
 LDCM0396  CL125 HEK-293T C69(0.97); C241(0.75); C283(0.95); C114(0.88)  LDD1600  [10]
 LDCM0397  CL126 HEK-293T C69(0.86); C241(0.85); C283(0.89); C307(0.93)  LDD1601  [10]
 LDCM0398  CL127 HEK-293T C69(1.00); C241(0.95); C283(0.94); C114(1.09)  LDD1602  [10]
 LDCM0399  CL128 HEK-293T C69(1.03); C241(0.87); C283(1.12); C307(1.03)  LDD1603  [10]
 LDCM0400  CL13 HEK-293T C69(1.12); C241(1.01); C283(0.90); C114(1.22)  LDD1604  [10]
 LDCM0401  CL14 HEK-293T C69(1.09); C241(1.28); C283(0.84); C307(1.04)  LDD1605  [10]
 LDCM0402  CL15 HEK-293T C69(1.04); C241(1.10); C283(0.95); C114(0.96)  LDD1606  [10]
 LDCM0403  CL16 PaTu 8988t C307(0.90)  LDD1282  [3]
 LDCM0404  CL17 PaTu 8988t C307(1.34)  LDD1283  [3]
 LDCM0405  CL18 PaTu 8988t C307(1.04)  LDD1284  [3]
 LDCM0406  CL19 PaTu 8988t C307(0.93)  LDD1285  [3]
 LDCM0407  CL2 HEK-293T C69(1.28); C241(1.14); C283(1.07); C307(1.18)  LDD1611  [10]
 LDCM0408  CL20 PaTu 8988t C307(0.96)  LDD1287  [3]
 LDCM0409  CL21 PaTu 8988t C307(1.26)  LDD1288  [3]
 LDCM0410  CL22 PaTu 8988t C307(1.16)  LDD1289  [3]
 LDCM0411  CL23 PaTu 8988t C307(0.83)  LDD1290  [3]
 LDCM0412  CL24 PaTu 8988t C307(0.85)  LDD1291  [3]
 LDCM0413  CL25 PaTu 8988t C307(1.48)  LDD1292  [3]
 LDCM0414  CL26 PaTu 8988t C307(1.22)  LDD1293  [3]
 LDCM0415  CL27 PaTu 8988t C307(1.08)  LDD1294  [3]
 LDCM0416  CL28 PaTu 8988t C307(1.00)  LDD1295  [3]
 LDCM0417  CL29 PaTu 8988t C307(0.86)  LDD1296  [3]
 LDCM0418  CL3 HEK-293T C69(1.02); C241(1.29); C283(1.03); C114(0.96)  LDD1622  [10]
 LDCM0419  CL30 PaTu 8988t C307(0.89)  LDD1298  [3]
 LDCM0420  CL31 HEK-293T C69(1.07); C241(1.05); C283(1.14); C307(1.12)  LDD1624  [10]
 LDCM0421  CL32 HEK-293T C69(0.95); C283(1.03); C114(1.12); C307(1.11)  LDD1625  [10]
 LDCM0422  CL33 HEK-293T C69(1.01); C283(0.94); C114(0.94); C307(0.99)  LDD1626  [10]
 LDCM0423  CL34 HEK-293T C69(0.94); C241(1.23); C283(0.98); C114(1.16)  LDD1627  [10]
 LDCM0424  CL35 HEK-293T C69(1.08); C283(1.10); C114(1.35); C307(1.02)  LDD1628  [10]
 LDCM0425  CL36 HEK-293T C69(1.09); C283(0.95); C307(0.99)  LDD1629  [10]
 LDCM0426  CL37 HEK-293T C69(1.19); C241(1.07); C283(1.01); C114(0.58)  LDD1630  [10]
 LDCM0428  CL39 HEK-293T C69(1.00); C241(1.26); C283(0.85); C114(1.09)  LDD1632  [10]
 LDCM0429  CL4 HEK-293T C69(1.00); C241(0.86); C283(1.24); C307(1.07)  LDD1633  [10]
 LDCM0430  CL40 HEK-293T C69(1.07); C241(1.26); C283(1.14); C307(1.04)  LDD1634  [10]
 LDCM0431  CL41 HEK-293T C69(0.93); C283(0.93); C114(0.92); C307(1.05)  LDD1635  [10]
 LDCM0432  CL42 HEK-293T C69(0.97); C283(1.19); C114(0.96); C307(1.03)  LDD1636  [10]
 LDCM0433  CL43 HEK-293T C69(0.97); C241(1.24); C283(1.18); C307(1.16)  LDD1637  [10]
 LDCM0434  CL44 HEK-293T C69(1.18); C283(1.28); C114(0.95); C307(1.15)  LDD1638  [10]
 LDCM0435  CL45 HEK-293T C69(1.13); C283(0.96); C114(1.05); C307(1.00)  LDD1639  [10]
 LDCM0436  CL46 PaTu 8988t C307(0.83)  LDD1315  [3]
 LDCM0437  CL47 PaTu 8988t C307(0.76)  LDD1316  [3]
 LDCM0438  CL48 PaTu 8988t C307(0.87)  LDD1317  [3]
 LDCM0439  CL49 PaTu 8988t C307(0.86)  LDD1318  [3]
 LDCM0440  CL5 HEK-293T C69(0.88); C283(1.08); C114(0.94); C307(1.14)  LDD1644  [10]
 LDCM0441  CL50 PaTu 8988t C307(0.85)  LDD1320  [3]
 LDCM0442  CL51 PaTu 8988t C307(0.85)  LDD1321  [3]
 LDCM0443  CL52 PaTu 8988t C307(0.78)  LDD1322  [3]
 LDCM0444  CL53 PaTu 8988t C307(0.67)  LDD1323  [3]
 LDCM0445  CL54 PaTu 8988t C307(0.73)  LDD1324  [3]
 LDCM0446  CL55 PaTu 8988t C307(0.74)  LDD1325  [3]
 LDCM0447  CL56 PaTu 8988t C307(0.15)  LDD1326  [3]
 LDCM0448  CL57 PaTu 8988t C307(0.74)  LDD1327  [3]
 LDCM0449  CL58 PaTu 8988t C307(0.66)  LDD1328  [3]
 LDCM0450  CL59 PaTu 8988t C307(0.71)  LDD1329  [3]
 LDCM0451  CL6 HEK-293T C69(0.84); C283(1.12); C114(1.30); C307(1.26)  LDD1654  [10]
 LDCM0452  CL60 PaTu 8988t C307(0.64)  LDD1331  [3]
 LDCM0453  CL61 PaTu 8988t C307(0.97)  LDD1332  [3]
 LDCM0454  CL62 PaTu 8988t C307(0.70)  LDD1333  [3]
 LDCM0455  CL63 PaTu 8988t C307(0.87)  LDD1334  [3]
 LDCM0456  CL64 PaTu 8988t C307(0.81)  LDD1335  [3]
 LDCM0457  CL65 PaTu 8988t C307(0.90)  LDD1336  [3]
 LDCM0458  CL66 PaTu 8988t C307(0.74)  LDD1337  [3]
 LDCM0459  CL67 PaTu 8988t C307(0.76)  LDD1338  [3]
 LDCM0460  CL68 PaTu 8988t C307(0.83)  LDD1339  [3]
 LDCM0461  CL69 PaTu 8988t C307(0.64)  LDD1340  [3]
 LDCM0462  CL7 HEK-293T C69(0.96); C241(0.88); C283(0.94); C307(1.11)  LDD1665  [10]
 LDCM0463  CL70 PaTu 8988t C307(0.92)  LDD1342  [3]
 LDCM0464  CL71 PaTu 8988t C307(0.88)  LDD1343  [3]
 LDCM0465  CL72 PaTu 8988t C307(0.86)  LDD1344  [3]
 LDCM0466  CL73 PaTu 8988t C307(0.47)  LDD1345  [3]
 LDCM0467  CL74 PaTu 8988t C307(0.89)  LDD1346  [3]
 LDCM0469  CL76 PaTu 8988t C307(0.90)  LDD1348  [3]
 LDCM0470  CL77 PaTu 8988t C307(0.85)  LDD1349  [3]
 LDCM0471  CL78 PaTu 8988t C307(0.64)  LDD1350  [3]
 LDCM0472  CL79 PaTu 8988t C307(0.69)  LDD1351  [3]
 LDCM0473  CL8 HEK-293T C69(0.90); C283(0.74); C114(0.92); C307(0.91)  LDD1676  [10]
 LDCM0474  CL80 PaTu 8988t C307(0.78)  LDD1353  [3]
 LDCM0475  CL81 PaTu 8988t C307(0.71)  LDD1354  [3]
 LDCM0476  CL82 PaTu 8988t C307(0.77)  LDD1355  [3]
 LDCM0477  CL83 PaTu 8988t C307(0.59)  LDD1356  [3]
 LDCM0478  CL84 PaTu 8988t C307(0.91)  LDD1357  [3]
 LDCM0479  CL85 PaTu 8988t C307(0.80)  LDD1358  [3]
 LDCM0480  CL86 PaTu 8988t C307(0.68)  LDD1359  [3]
 LDCM0481  CL87 PaTu 8988t C307(0.67)  LDD1360  [3]
 LDCM0482  CL88 PaTu 8988t C307(0.63)  LDD1361  [3]
 LDCM0483  CL89 PaTu 8988t C307(0.83)  LDD1362  [3]
 LDCM0484  CL9 HEK-293T C69(1.64); C283(0.85); C114(1.05); C307(1.02)  LDD1687  [10]
 LDCM0485  CL90 PaTu 8988t C307(0.58)  LDD1364  [3]
 LDCM0486  CL91 HEK-293T C69(0.92); C241(0.87); C283(1.11); C307(1.17)  LDD1689  [10]
 LDCM0487  CL92 HEK-293T C69(1.25); C283(1.08); C114(0.90); C307(1.03)  LDD1690  [10]
 LDCM0488  CL93 HEK-293T C69(1.23); C283(0.93); C114(1.00); C307(1.03)  LDD1691  [10]
 LDCM0489  CL94 HEK-293T C69(1.06); C241(1.39); C283(0.84); C114(1.07)  LDD1692  [10]
 LDCM0490  CL95 HEK-293T C69(0.93); C283(0.85); C114(1.09); C307(0.99)  LDD1693  [10]
 LDCM0491  CL96 HEK-293T C69(0.99); C283(1.09); C307(1.02)  LDD1694  [10]
 LDCM0492  CL97 HEK-293T C69(0.94); C241(0.99); C283(1.16); C114(0.80)  LDD1695  [10]
 LDCM0493  CL98 HEK-293T C69(1.15); C241(1.13); C283(0.82); C307(0.98)  LDD1696  [10]
 LDCM0494  CL99 HEK-293T C69(0.86); C241(1.08); C283(0.79); C114(1.06)  LDD1697  [10]
 LDCM0495  E2913 HEK-293T C69(1.02); C241(1.24); C283(0.98); C114(1.22)  LDD1698  [10]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C307(4.63)  LDD1702  [11]
 LDCM0625  F8 Ramos C69(1.58)  LDD2187  [12]
 LDCM0572  Fragment10 Ramos C69(1.11)  LDD2189  [12]
 LDCM0573  Fragment11 Ramos C69(0.04)  LDD2190  [12]
 LDCM0574  Fragment12 Ramos C69(0.78)  LDD2191  [12]
 LDCM0575  Fragment13 Ramos C69(0.93)  LDD2192  [12]
 LDCM0576  Fragment14 Ramos C69(0.98)  LDD2193  [12]
 LDCM0579  Fragment20 Ramos C69(0.71)  LDD2194  [12]
 LDCM0580  Fragment21 Ramos C69(1.02)  LDD2195  [12]
 LDCM0582  Fragment23 Ramos C69(0.62)  LDD2196  [12]
 LDCM0578  Fragment27 Ramos C69(0.97)  LDD2197  [12]
 LDCM0586  Fragment28 Ramos C69(0.76)  LDD2198  [12]
 LDCM0588  Fragment30 Ramos C69(1.05)  LDD2199  [12]
 LDCM0589  Fragment31 Ramos C69(1.00)  LDD2200  [12]
 LDCM0590  Fragment32 Ramos C69(0.68)  LDD2201  [12]
 LDCM0468  Fragment33 PaTu 8988t C307(0.76)  LDD1347  [3]
 LDCM0596  Fragment38 Ramos C69(0.99)  LDD2203  [12]
 LDCM0566  Fragment4 Ramos C69(1.20)  LDD2184  [12]
 LDCM0427  Fragment51 HEK-293T C69(1.07); C241(1.26); C283(1.10); C307(1.00)  LDD1631  [10]
 LDCM0610  Fragment52 Ramos C69(1.21)  LDD2204  [12]
 LDCM0614  Fragment56 Ramos C69(1.52)  LDD2205  [12]
 LDCM0569  Fragment7 Ramos C69(0.85)  LDD2186  [12]
 LDCM0571  Fragment9 Ramos C69(1.13)  LDD2188  [12]
 LDCM0022  KB02 HCT 116 C69(1.08)  LDD0080  [3]
 LDCM0023  KB03 HCT 116 C69(0.96)  LDD0081  [3]
 LDCM0024  KB05 HCT 116 C69(1.05)  LDD0082  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Fibronectin type III and SPRY domain-containing protein 2 (FSD2) . A1L4K1
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) . Q9Y680
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Calpain small subunit 2 (CAPNS2) . Q96L46

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
5 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
6 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
7 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
8 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
9 Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8551-6. doi: 10.1002/anie.201300683. Epub 2013 Jun 10.
10 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
11 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
12 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578