Details of the Target

General Information of Target

Target ID LDTP16564
Target Name Zinc finger protein 320 (ZNF320)
Gene Name ZNF320
Gene ID 162967
Synonyms
Zinc finger protein 320
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MRLPAQLLGLLMLWIPGSSADIVMTQTPLSLSVTPGQPASISCKSSQSLLHSDGKTYLYW
YLQKPGQSPQLLIYEVSSRFSGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQGIHLP
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
A2RRD8
Ensemble ID
ENST00000391781.6
HGNC ID
HGNC:13842

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Probe 1
 Probe Info  		Y41(17.56)  LDD3495  [1]
DBIA
 Probe Info  		C496(1.22)  LDD0531  [2]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [3]
TFBX
 Probe Info  		N.A.  LDD0148  [4]
HHS-465
 Probe Info  		K159(0.00); K162(0.00); K271(0.00); K274(0.00)  LDD2240  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C496(1.22)  LDD0531  [2]
 LDCM0215  AC10 HCT 116 C496(1.14)  LDD0532  [2]
 LDCM0226  AC11 HCT 116 C496(1.03)  LDD0543  [2]
 LDCM0230  AC113 HCT 116 C496(1.03)  LDD0547  [2]
 LDCM0231  AC114 HCT 116 C496(1.18)  LDD0548  [2]
 LDCM0232  AC115 HCT 116 C496(1.32)  LDD0549  [2]
 LDCM0233  AC116 HCT 116 C496(1.27)  LDD0550  [2]
 LDCM0234  AC117 HCT 116 C496(1.06)  LDD0551  [2]
 LDCM0235  AC118 HCT 116 C496(1.12)  LDD0552  [2]
 LDCM0236  AC119 HCT 116 C496(1.13)  LDD0553  [2]
 LDCM0237  AC12 HCT 116 C496(0.99)  LDD0554  [2]
 LDCM0238  AC120 HCT 116 C496(1.14)  LDD0555  [2]
 LDCM0239  AC121 HCT 116 C496(1.05)  LDD0556  [2]
 LDCM0240  AC122 HCT 116 C496(1.09)  LDD0557  [2]
 LDCM0241  AC123 HCT 116 C496(1.06)  LDD0558  [2]
 LDCM0242  AC124 HCT 116 C496(0.98)  LDD0559  [2]
 LDCM0243  AC125 HCT 116 C496(1.10)  LDD0560  [2]
 LDCM0244  AC126 HCT 116 C496(1.22)  LDD0561  [2]
 LDCM0245  AC127 HCT 116 C496(1.17)  LDD0562  [2]
 LDCM0259  AC14 HCT 116 C496(1.06)  LDD0576  [2]
 LDCM0270  AC15 HCT 116 C496(1.14)  LDD0587  [2]
 LDCM0276  AC17 HCT 116 C496(1.08)  LDD0593  [2]
 LDCM0277  AC18 HCT 116 C496(1.23)  LDD0594  [2]
 LDCM0278  AC19 HCT 116 C496(1.20)  LDD0595  [2]
 LDCM0279  AC2 HCT 116 C496(1.07)  LDD0596  [2]
 LDCM0280  AC20 HCT 116 C496(1.22)  LDD0597  [2]
 LDCM0281  AC21 HCT 116 C496(1.18)  LDD0598  [2]
 LDCM0282  AC22 HCT 116 C496(1.18)  LDD0599  [2]
 LDCM0283  AC23 HCT 116 C496(1.14)  LDD0600  [2]
 LDCM0284  AC24 HCT 116 C496(1.05)  LDD0601  [2]
 LDCM0285  AC25 HCT 116 C496(1.14)  LDD0602  [2]
 LDCM0286  AC26 HCT 116 C496(1.18)  LDD0603  [2]
 LDCM0287  AC27 HCT 116 C496(1.22)  LDD0604  [2]
 LDCM0288  AC28 HCT 116 C496(1.10)  LDD0605  [2]
 LDCM0289  AC29 HCT 116 C496(1.07)  LDD0606  [2]
 LDCM0290  AC3 HCT 116 C496(1.04)  LDD0607  [2]
 LDCM0291  AC30 HCT 116 C496(1.20)  LDD0608  [2]
 LDCM0292  AC31 HCT 116 C496(1.28)  LDD0609  [2]
 LDCM0293  AC32 HCT 116 C496(1.24)  LDD0610  [2]
 LDCM0294  AC33 HCT 116 C496(1.19)  LDD0611  [2]
 LDCM0295  AC34 HCT 116 C496(1.21)  LDD0612  [2]
 LDCM0296  AC35 HCT 116 C496(1.04)  LDD0613  [2]
 LDCM0297  AC36 HCT 116 C496(1.08)  LDD0614  [2]
 LDCM0298  AC37 HCT 116 C496(1.09)  LDD0615  [2]
 LDCM0299  AC38 HCT 116 C496(1.06)  LDD0616  [2]
 LDCM0300  AC39 HCT 116 C496(1.15)  LDD0617  [2]
 LDCM0301  AC4 HCT 116 C496(1.05)  LDD0618  [2]
 LDCM0302  AC40 HCT 116 C496(1.29)  LDD0619  [2]
 LDCM0303  AC41 HCT 116 C496(1.15)  LDD0620  [2]
 LDCM0304  AC42 HCT 116 C496(0.99)  LDD0621  [2]
 LDCM0305  AC43 HCT 116 C496(1.22)  LDD0622  [2]
 LDCM0306  AC44 HCT 116 C496(1.33)  LDD0623  [2]
 LDCM0307  AC45 HCT 116 C496(1.37)  LDD0624  [2]
 LDCM0312  AC5 HCT 116 C496(1.05)  LDD0629  [2]
 LDCM0320  AC57 HCT 116 C496(1.56)  LDD0637  [2]
 LDCM0321  AC58 HCT 116 C496(1.51)  LDD0638  [2]
 LDCM0322  AC59 HCT 116 C496(1.70)  LDD0639  [2]
 LDCM0323  AC6 HCT 116 C496(1.14)  LDD0640  [2]
 LDCM0324  AC60 HCT 116 C496(1.54)  LDD0641  [2]
 LDCM0325  AC61 HCT 116 C496(1.39)  LDD0642  [2]
 LDCM0326  AC62 HCT 116 C496(1.72)  LDD0643  [2]
 LDCM0327  AC63 HCT 116 C496(1.41)  LDD0644  [2]
 LDCM0328  AC64 HCT 116 C496(1.55)  LDD0645  [2]
 LDCM0329  AC65 HCT 116 C496(1.69)  LDD0646  [2]
 LDCM0330  AC66 HCT 116 C496(1.70)  LDD0647  [2]
 LDCM0331  AC67 HCT 116 C496(1.94)  LDD0648  [2]
 LDCM0332  AC68 HCT 116 C496(0.88)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C496(0.92)  LDD0650  [2]
 LDCM0334  AC7 HCT 116 C496(1.00)  LDD0651  [2]
 LDCM0335  AC70 HCT 116 C496(1.00)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C496(0.88)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C496(0.91)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C496(1.10)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C496(0.93)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C496(0.91)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C496(0.90)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C496(0.94)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C496(1.04)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C496(1.00)  LDD0661  [2]
 LDCM0345  AC8 HCT 116 C496(1.11)  LDD0662  [2]
 LDCM0346  AC80 HCT 116 C496(0.98)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C496(0.84)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C496(0.92)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C496(1.49)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C496(1.32)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C496(1.22)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C496(1.24)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C496(1.05)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C496(1.19)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C496(1.28)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C496(1.00)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C496(1.42)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C496(1.38)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C496(1.28)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C496(1.27)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C496(1.08)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C496(1.24)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C496(1.32)  LDD0681  [2]
 LDCM0248  AKOS034007472 HCT 116 C496(1.01)  LDD0565  [2]
 LDCM0356  AKOS034007680 HCT 116 C496(1.05)  LDD0673  [2]
 LDCM0275  AKOS034007705 HCT 116 C496(1.48)  LDD0592  [2]
 LDCM0369  CL100 HCT 116 C496(1.13)  LDD0686  [2]
 LDCM0370  CL101 HCT 116 C496(1.14)  LDD0687  [2]
 LDCM0371  CL102 HCT 116 C496(0.93)  LDD0688  [2]
 LDCM0372  CL103 HCT 116 C496(0.91)  LDD0689  [2]
 LDCM0373  CL104 HCT 116 C496(1.04)  LDD0690  [2]
 LDCM0374  CL105 HCT 116 C496(1.19)  LDD0691  [2]
 LDCM0375  CL106 HCT 116 C496(1.18)  LDD0692  [2]
 LDCM0376  CL107 HCT 116 C496(1.10)  LDD0693  [2]
 LDCM0377  CL108 HCT 116 C496(1.11)  LDD0694  [2]
 LDCM0378  CL109 HCT 116 C496(1.23)  LDD0695  [2]
 LDCM0380  CL110 HCT 116 C496(1.07)  LDD0697  [2]
 LDCM0381  CL111 HCT 116 C496(1.09)  LDD0698  [2]
 LDCM0382  CL112 HCT 116 C496(1.19)  LDD0699  [2]
 LDCM0383  CL113 HCT 116 C496(1.13)  LDD0700  [2]
 LDCM0384  CL114 HCT 116 C496(1.13)  LDD0701  [2]
 LDCM0385  CL115 HCT 116 C496(1.12)  LDD0702  [2]
 LDCM0386  CL116 HCT 116 C496(1.23)  LDD0703  [2]
 LDCM0387  CL117 HCT 116 C496(1.12)  LDD0704  [2]
 LDCM0388  CL118 HCT 116 C496(1.00)  LDD0705  [2]
 LDCM0389  CL119 HCT 116 C496(1.03)  LDD0706  [2]
 LDCM0391  CL120 HCT 116 C496(1.15)  LDD0708  [2]
 LDCM0396  CL125 HCT 116 C496(1.10)  LDD0713  [2]
 LDCM0397  CL126 HCT 116 C496(1.11)  LDD0714  [2]
 LDCM0398  CL127 HCT 116 C496(1.15)  LDD0715  [2]
 LDCM0399  CL128 HCT 116 C496(1.53)  LDD0716  [2]
 LDCM0403  CL16 HCT 116 C496(1.02)  LDD0720  [2]
 LDCM0404  CL17 HCT 116 C496(0.93)  LDD0721  [2]
 LDCM0405  CL18 HCT 116 C496(1.08)  LDD0722  [2]
 LDCM0406  CL19 HCT 116 C496(1.13)  LDD0723  [2]
 LDCM0408  CL20 HCT 116 C496(1.18)  LDD0725  [2]
 LDCM0409  CL21 HCT 116 C496(1.16)  LDD0726  [2]
 LDCM0410  CL22 HCT 116 C496(1.49)  LDD0727  [2]
 LDCM0411  CL23 HCT 116 C496(1.15)  LDD0728  [2]
 LDCM0412  CL24 HCT 116 C496(1.21)  LDD0729  [2]
 LDCM0413  CL25 HCT 116 C496(1.14)  LDD0730  [2]
 LDCM0414  CL26 HCT 116 C496(1.13)  LDD0731  [2]
 LDCM0415  CL27 HCT 116 C496(1.18)  LDD0732  [2]
 LDCM0416  CL28 HCT 116 C496(1.14)  LDD0733  [2]
 LDCM0417  CL29 HCT 116 C496(1.18)  LDD0734  [2]
 LDCM0419  CL30 HCT 116 C496(1.04)  LDD0736  [2]
 LDCM0420  CL31 HCT 116 C496(0.97)  LDD0737  [2]
 LDCM0436  CL46 HCT 116 C496(0.77)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C496(0.84)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C496(0.75)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C496(0.86)  LDD0756  [2]
 LDCM0441  CL50 HCT 116 C496(0.81)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C496(0.87)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C496(0.87)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C496(0.81)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C496(0.74)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C496(0.75)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C496(0.92)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C496(0.86)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C496(0.84)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C496(0.99)  LDD0767  [2]
 LDCM0452  CL60 HCT 116 C496(0.84)  LDD0769  [2]
 LDCM0453  CL61 HCT 116 C496(1.09)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C496(1.13)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C496(1.33)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C496(1.31)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C496(1.24)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C496(1.64)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C496(1.46)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C496(1.35)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C496(1.09)  LDD0778  [2]
 LDCM0463  CL70 HCT 116 C496(1.26)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C496(1.49)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C496(1.21)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C496(1.31)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C496(1.31)  LDD0784  [2]
 LDCM0486  CL91 HCT 116 C496(1.03)  LDD0803  [2]
 LDCM0487  CL92 HCT 116 C496(0.90)  LDD0804  [2]
 LDCM0488  CL93 HCT 116 C496(0.93)  LDD0805  [2]
 LDCM0489  CL94 HCT 116 C496(1.14)  LDD0806  [2]
 LDCM0490  CL95 HCT 116 C496(0.96)  LDD0807  [2]
 LDCM0491  CL96 HCT 116 C496(1.04)  LDD0808  [2]
 LDCM0492  CL97 HCT 116 C496(0.93)  LDD0809  [2]
 LDCM0493  CL98 HCT 116 C496(1.08)  LDD0810  [2]
 LDCM0494  CL99 HCT 116 C496(1.09)  LDD0811  [2]
 LDCM0468  Fragment33 HCT 116 C496(1.22)  LDD0785  [2]
 LDCM0022  KB02 697 C496(1.38)  LDD2245  [6]
 LDCM0023  KB03 697 C496(1.58)  LDD2662  [6]
 LDCM0024  KB05 MEWO C496(1.63)  LDD3319  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Keratin-associated protein 10-5 (KRTAP10-5) KRTAP type 10 family P60370
Keratin-associated protein 10-7 (KRTAP10-7) KRTAP type 10 family P60409

References

1 An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
4 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
5 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010
6 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840